Reactome | AHCTF1 [cytosol]

AHCTF1 [cytosol]

Stable Identifier

R-BTA-376244

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

AHCTF1, A0A3Q1MMV9

Locations in the PathwayBrowser

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Cell Cycle (Bos taurus)

- Cell Cycle Checkpoints (Bos taurus)
  - Mitotic Spindle Checkpoint (Bos taurus)
    - Amplification of signal from the kinetochores (Bos taurus)
      - Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Bos taurus)
        
        MAD2 associates with the Mad1 kinetochore complex (Bos taurus)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Bos taurus)
        
        Mad1:kinetochore complex [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Mad1:kinetochore complex [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        MAD2 converted to an inhibitory state via interaction with Mad1 (Bos taurus)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Bos taurus)
        
        Mad1:kinetochore complex [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Mad1 binds kinetochore (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Mad1:kinetochore complex [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Release of activated MAD2 from kinetochores (Bos taurus)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Bos taurus)
        
        Mad1:kinetochore complex [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Mad1:kinetochore complex [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
- Cell Cycle, Mitotic (Bos taurus)
  - M Phase (Bos taurus)
    - Mitotic Metaphase and Anaphase (Bos taurus)
      - Mitotic Anaphase (Bos taurus)
        
        Nuclear Envelope (NE) Reassembly (Bos taurus)
        
        Postmitotic nuclear pore complex (NPC) reformation (Bos taurus)
        
        AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        POM121 and NDC1 bind the Nup93 complex (Bos taurus)
        
        Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin [nuclear envelope] (Bos taurus)
        
        POM121:Nup107-160 complex:AHCTF1:Chromatin [nuclear envelope] (Bos taurus)
        
        Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        POM121:Nup107-160 complex:AHCTF1:Chromatin [nuclear envelope] (Bos taurus)
        
        Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        POM121 binds the Nup107-Nup160 complex (Bos taurus)
        
        Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        POM121:Nup107-160 complex:AHCTF1:Chromatin [nuclear envelope] (Bos taurus)
        
        Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Separation of Sister Chromatids (Bos taurus)
        
        ESPL1 (Separase) cleaves centromeric cohesin (Bos taurus)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
        
        Microtubule-bound kinetochore [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Separation of sister chromatids (Bos taurus)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Sister Centromere:Kinetochore:Microtubules [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
    - Mitotic Prometaphase (Bos taurus)
      - EML4 and NUDC in mitotic spindle formation (Bos taurus)
        
        EML4 recruits NUDC to mitotic spindle (Bos taurus)
        
        Microtubule-bound kinetochore [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Bos taurus)
        
        Microtubule-bound kinetochore [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
      - Resolution of Sister Chromatid Cohesion (Bos taurus)
        
        CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
        
        Microtubule-bound kinetochore [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Kinetochore assembly (Bos taurus)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Microtubule-bound kinetochore [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        PP2A-B56 dephosphorylates centromeric cohesin (Bos taurus)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
        
        Microtubule-bound kinetochore [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
        
        Microtubule-bound kinetochore [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        Phosphorylation of cohesin by PLK1 at centromeres (Bos taurus)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
        
        Microtubule-bound kinetochore [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
        
        Microtubule-bound kinetochore [cytosol] (Bos taurus)
        
        Kinetochore [cytosol] (Bos taurus)
        
        AHCTF1 [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:A0A3Q1MMV9

Gene Names

AHCTF1

Reference Genes

ENSEMBL:ENSBTAG00000013949.6

KEGG:bta:504716 AHCTF1

UCSC:A0A3Q1MMV9 AHCTF1

Other Identifiers

504716

Bt.13722.1.S1_at

Bt.13722.2.A1_at

GO:0005737

GO:0016363

Participates

as a component of

as an input of

AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex (Bos taurus)

Inferred From

AHCTF1 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSBTAT00000077376, ENSBTAP00000073178, ENSBTAG00000013949

VGNC

25749

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