Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
NSL1 [cytosol]
Stable Identifier
R-BTA-375309
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
NSL1, A6QQ16
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle Checkpoints (Bos taurus)
Mitotic Spindle Checkpoint (Bos taurus)
Amplification of signal from the kinetochores (Bos taurus)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Bos taurus)
MAD2 associates with the Mad1 kinetochore complex (Bos taurus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
MAD2 converted to an inhibitory state via interaction with Mad1 (Bos taurus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Mad1 binds kinetochore (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Release of activated MAD2 from kinetochores (Bos taurus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Separation of Sister Chromatids (Bos taurus)
ESPL1 (Separase) cleaves centromeric cohesin (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Separation of sister chromatids (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Mitotic Prometaphase (Bos taurus)
EML4 and NUDC in mitotic spindle formation (Bos taurus)
EML4 recruits NUDC to mitotic spindle (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Resolution of Sister Chromatid Cohesion (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Kinetochore assembly (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
PP2A-B56 dephosphorylates centromeric cohesin (Bos taurus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Phosphorylation of cohesin by PLK1 at centromeres (Bos taurus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases Activate Formins (Bos taurus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Bos taurus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
CDC42:GTP recruits DIAPH2-2 to kinetochores (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
KMN network [cytosol] (Bos taurus)
Mis12 complex [cytosol] (Bos taurus)
NSL1 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:A6QQ16
Gene Names
NSL1
Reference Genes
BioGPS Gene:506867 NSL1
ENSEMBL:ENSBTAG00000011340.6
KEGG:bta:506867 NSL1
Monarch:506867 NSL1
NCBI Gene:506867 NSL1
UCSC:A6QQ16 NSL1
Reference Transcript
RefSeq:NM_001101876.1 NSL1
Participates
as a component of
Mis12 complex [cytosol] (Bos taurus)
Inferred From
NSL1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001095346.1
VGNC
32277
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
