Reactome | OPRD1 [plasma membrane]

OPRD1 [plasma membrane]

Stable Identifier

R-BTA-374265

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

plasma membrane

Synonyms

OPRD1, F1N083

Locations in the PathwayBrowser

Expand all

Signal Transduction (Bos taurus)

- Signaling by GPCR (Bos taurus)
  - GPCR downstream signalling (Bos taurus)
    - G alpha (i) signalling events (Bos taurus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Opioid receptor:opioid ligand [plasma membrane] (Bos taurus)
        
        Opioid receptors [plasma membrane] (Bos taurus)
        
        OPRD1 [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Opioid receptor:opioid ligand [plasma membrane] (Bos taurus)
        
        Opioid receptors [plasma membrane] (Bos taurus)
        
        OPRD1 [plasma membrane] (Bos taurus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Opioid receptor:opioid ligand [plasma membrane] (Bos taurus)
        
        Opioid receptors [plasma membrane] (Bos taurus)
        
        OPRD1 [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Opioid receptor:opioid ligand [plasma membrane] (Bos taurus)
        
        Opioid receptors [plasma membrane] (Bos taurus)
        
        OPRD1 [plasma membrane] (Bos taurus)
      - The Ligand:GPCR:Gi complex dissociates (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Opioid receptor:opioid ligand [plasma membrane] (Bos taurus)
        
        Opioid receptors [plasma membrane] (Bos taurus)
        
        OPRD1 [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
        
        Opioid receptor:opioid ligand [plasma membrane] (Bos taurus)
        
        Opioid receptors [plasma membrane] (Bos taurus)
        
        OPRD1 [plasma membrane] (Bos taurus)
  - GPCR ligand binding (Bos taurus)
    - Class A/1 (Rhodopsin-like receptors) (Bos taurus)
      - Peptide ligand-binding receptors (Bos taurus)
        
        Opioid receptors bind opioid peptides (Bos taurus)
        
        Opioid receptor:opioid ligand [plasma membrane] (Bos taurus)
        
        Opioid receptors [plasma membrane] (Bos taurus)
        
        OPRD1 [plasma membrane] (Bos taurus)
        
        Opioid receptors [plasma membrane] (Bos taurus)
        
        OPRD1 [plasma membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:F1N083

Gene Names

OPRD1

Reference Genes

BioGPS Gene:781956 OPRD1

ENSEMBL:ENSBTAG00000003202.6

KEGG:bta:781956 OPRD1

Monarch:781956 OPRD1

NCBI Gene:781956 OPRD1

UCSC:F1N083 OPRD1

Reference Transcript

RefSeq:NM_001191148.1 OPRD1

Other Identifiers

781956

GO:0004930

GO:0004985

GO:0005886

GO:0007186

GO:0007193

GO:0007218

GO:0008344

GO:0010629

GO:0016020

GO:0031333

GO:0038003

GO:0038046

GO:0051881

GO:0071456

GO:0097237

GO:0098992

Participates

as a member of

Opioid receptors [plasma membrane] (Bos taurus)

Inferred From

OPRD1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001178077.1

ENSEMBL

ENSBTAG00000003202, ENSBTAP00000004157, ENSBTAT00000004157

ZINC - Substances

F1N083_BOVIN

ZINC target

F1N083

VGNC

50539

ZINC - Predictions - Purchasable

F1N083_BOVIN