Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
SARM1 [cytosol]
Stable Identifier
R-BTA-2559572
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
SARM-1, E1BIR9
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 4 (TLR4) Cascade (Bos taurus)
MyD88-independent TLR4 cascade (Bos taurus)
SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 (Bos taurus)
SARM1 [cytosol] (Bos taurus)
SARM:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
SARM1 [cytosol] (Bos taurus)
TRIF (TICAM1)-mediated TLR4 signaling (Bos taurus)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Bos taurus)
TRAF3 binds TICAM1:activated TLR4 complex (Bos taurus)
SARM:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
SARM1 [cytosol] (Bos taurus)
IKK complex recruitment mediated by RIP1 (Bos taurus)
TRIF:activated TLR3/TLR4 complex recruits RIP1 (Bos taurus)
SARM:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
SARM1 [cytosol] (Bos taurus)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Bos taurus)
Activated TLR4:TICAM1 recruits TRAF6 (Bos taurus)
SARM:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
SARM1 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:E1BIR9
Gene Names
SARM1
Reference Genes
BioGPS Gene:536256 SARM1
ENSEMBL:ENSBTAG00000002816.6
Monarch:536256 SARM1
NCBI Gene:536256 SARM1
UCSC:E1BIR9 SARM1
Reference Transcript
RefSeq:NM_001435053.1 SARM1
Other Identifiers
536256
GO:0003953
GO:0005515
GO:0005737
GO:0005739
GO:0005741
GO:0005856
GO:0005874
GO:0007165
GO:0009749
GO:0009986
GO:0015630
GO:0016787
GO:0019677
GO:0030425
GO:0031594
GO:0032991
GO:0034128
GO:0035591
GO:0043523
GO:0045202
GO:0048678
GO:0048814
GO:0050877
GO:0055086
GO:0060090
GO:0061809
GO:0070585
GO:1905806
Participates
as an input of
SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 (Bos taurus)
as a component of
SARM:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Inferred From
SARM-1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001421982.1
ENSEMBL
ENSBTAG00000002816
,
ENSBTAT00000003645
,
ENSBTAP00000003645
VGNC
34290
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text