Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Integrin alphaVbeta3 [plasma membrane]
Stable Identifier
R-BTA-210216
Type
Complex
Species
Bos taurus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to mechanical stimuli (Bos taurus)
Response of endothelial cells to shear stress (Bos taurus)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Bos taurus)
Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Extracellular matrix organization (Bos taurus)
ECM proteoglycans (Bos taurus)
Dentin matrix protein 1 binds integrin alphaVbeta3 (Bos taurus)
DMP1:Integrin alphVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Bos taurus)
Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
TNC:Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 (Bos taurus)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
VTN:Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Bos taurus)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Elastic fibre formation (Bos taurus)
Fibrillin-1 binds integrins (Bos taurus)
Fibrilin-1:Fibrilin-binding integrins [plasma membrane] (Bos taurus)
Fibrilin-binding integrins [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Fibrilin-binding integrins [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Molecules associated with elastic fibres (Bos taurus)
Latent TGF-beta-1 binds integrins (Bos taurus)
LAP1 binding-integrins [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Bos taurus)
LAP1 binding-integrins [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Latent TGF-beta-3 binds integrins (Bos taurus)
LAP3-binding integrins [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Bos taurus)
LAP3-binding integrins [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin cell surface interactions (Bos taurus)
COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Bos taurus)
COMP pentamer:Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Bos taurus)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Canstatin binds integrins alphaVbeta3, alphaVbeta5 (Bos taurus)
Canstatin:Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Bos taurus)
Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 (Bos taurus)
Endostatin:Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Bos taurus)
Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Bos taurus)
Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alpha4beta1, alpha8beta1, alphaVbeta6:Fibronectin matrix [plasma membrane] (Bos taurus)
Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Interaction of integrin alphaVbeta3 with Fibrillin (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3:Fibrillin-1 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3:IBSP [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Interaction of integrin alphaVbeta3 with PECAM1 (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3:PECAM1 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Interaction of integrin alphaVbeta3 with Tenascin (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3:Tenascin [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Interaction of integrin alphaVbeta3 with von Willbrand Factor (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3:VWF multimer [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Tumstatin binds integrin alphaVbeta 3, alpha3beta1 (Bos taurus)
Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Tumstatin:Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Bos taurus)
Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Bos taurus)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
VTN:Integrin alphaVbeta3, 5, 8 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Non-integrin membrane-ECM interactions (Bos taurus)
Syndecan interactions (Bos taurus)
Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) (Bos taurus)
Integrin alpha2beta1, (alpha6beta4) [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Syndecan-1:Integrin alpha2beta1 (alpha6beta4) [plasma membrane] (Bos taurus)
Integrin alpha2beta1, (alpha6beta4) [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Hemostasis (Bos taurus)
Cell surface interactions at the vascular wall (Bos taurus)
PECAM1 interactions (Bos taurus)
Interaction of integrin alphaVbeta3 with PECAM1 (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3:PECAM1 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
PTK2beta binds alphaVbeta3 (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
SRC-1 phosphorylates PTK2-beta (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:p-Y402-PTK2B [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:p-Y402-PTK2B [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Signaling by TGFB family members (Bos taurus)
Signaling by TGF-beta Receptor Complex (Bos taurus)
TGF-beta receptor signaling activates SMADs (Bos taurus)
Latent TGF-beta-1 binds integrins (Bos taurus)
LAP1 binding-integrins [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Bos taurus)
LAP1 binding-integrins [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
Latent TGF-beta-3 binds integrins (Bos taurus)
LAP3-binding integrins [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Bos taurus)
LAP3-binding integrins [plasma membrane] (Bos taurus)
Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
ITGAV [plasma membrane]
(Bos taurus)
ITGB3 [plasma membrane]
(Bos taurus)
Participates
as a member of
Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Bos taurus)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Bos taurus)
Integrin alpha2beta1, (alpha6beta4) [plasma membrane] (Bos taurus)
Fibrilin-binding integrins [plasma membrane] (Bos taurus)
Integrins [plasma membrane] (Bos taurus)
Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Bos taurus)
Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Bos taurus)
Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Bos taurus)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Bos taurus)
Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Bos taurus)
LAP1 binding-integrins [plasma membrane] (Bos taurus)
LAP3-binding integrins [plasma membrane] (Bos taurus)
as an input of
Dentin matrix protein 1 binds integrin alphaVbeta3 (Bos taurus)
Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Bos taurus)
Interaction of integrin alphaVbeta3 with Tenascin (Bos taurus)
Interaction of integrin alphaVbeta3 with Fibrillin (Bos taurus)
Interaction of integrin alphaVbeta3 with PECAM1 (Bos taurus)
Interaction of integrin alphaVbeta3 with von Willbrand Factor (Bos taurus)
Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Bos taurus)
as a component of
DMP1:Integrin alphVbeta3 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3:IBSP [plasma membrane] (Bos taurus)
Integrin alphaVbeta3:Tenascin [plasma membrane] (Bos taurus)
Integrin alphaVbeta3:Fibrillin-1 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3:PECAM1 [plasma membrane] (Bos taurus)
Integrin alphaVbeta3:VWF multimer [plasma membrane] (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Bos taurus)
This entity regulates
Positively
Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow
(Bos taurus)
Inferred From
Integrin alphaVbeta3 [plasma membrane]
(Homo sapiens)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
