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About
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SH3KBP1 [cytosol]
Stable Identifier
R-BTA-182957
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
F1MVN9
Locations in the PathwayBrowser
Expand all
Developmental Biology (Bos taurus)
Axon guidance (Bos taurus)
Reelin signalling pathway (Bos taurus)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Bos taurus)
RELN:VLDLR:DAB1:SH3KBP1 [plasma membrane] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
RELN:VLDLR:p-Y198,220,232-DAB1:SH3KBP1 [plasma membrane] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by EGFR (Bos taurus)
EGFR downregulation (Bos taurus)
Assembly of EGFR complex in clathrin-coated vesicles (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
CBL-mediated ubiquitination of CIN85 (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
EGFR binds EPS15, EPN1, EPS15L1 (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
EGFR non-clathrin mediated endocytosis (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
EGFR phosphorylates EPS15 (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
PTPN3 dephosphorylates EPS15 (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
Sprouty sequesters CBL away from active EGFR (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:SPRY1/2:Endophilin:Epsin:Eps15L1:EPS15 [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
Vesicle-mediated transport (Bos taurus)
Membrane Trafficking (Bos taurus)
Clathrin-mediated endocytosis (Bos taurus)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
BAR domain proteins recruit dynamin (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
Cargo recognition for clathrin-mediated endocytosis (Bos taurus)
Epsin family proteins bind ubiquitinated cargo (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
Clathrin recruits PIK3C2A (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
Clathrin recruits auxilins to the clathrin-coated vesicle (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Bos taurus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Bos taurus)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
Dissociation of clathrin-associated proteins (Bos taurus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Bos taurus)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
Endophilins recruit synaptojanins to the clathrin-coated pit (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
F- and N- BAR domain proteins bind the clathrin-coated pit (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
RAB5 and GAPVD1 bind AP-2 (Bos taurus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
SNX9 recruits components of the actin polymerizing machinery (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Bos taurus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Bos taurus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Bos taurus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Bos taurus)
CLASP proteins:cargo [plasma membrane] (Bos taurus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Bos taurus)
ubiquitinated cargo [plasma membrane] (Bos taurus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Bos taurus)
CIN85:endophilin [cytosol] (Bos taurus)
SH3KBP1 tetramer [cytosol] (Bos taurus)
SH3KBP1 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:F1MVN9
Reference Genes
ENSEMBL:ENSBTAG00000003727
Other Identifiers
510489
DAAA02074544
ENSBTAG00000003727
ENSBTAP00000004853
ENSBTAT00000004853
EntrezGene:510489
GO:0003674
GO:0005515
IPR001452
IPR035771
IPR035772
IPR036028
PF14604
PR00452
PR01887
SH3KBP1
SH3KBP1-205
SM00326
UPI00005C0AAE
VGNC:34577
XM_024987859
XM_024987862
XM_024987866
XM_024987867
XP_024843627
XP_024843630
XP_024843634
XP_024843635
Participant Of
hasComponent
RELN:VLDLR:DAB1:SH3KBP1 [plasma membrane]
RELN:VLDLR:p-Y198,220,232-DAB1:SH3KBP1 [plasma membrane]
SH3KBP1 tetramer [cytosol]
Other forms of this molecule
Ub-SH3KBP1 [cytosol]
SH3KBP1 [plasma membrane]
Inferred From
SH3KBP1 [cytosol] (Homo sapiens)
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