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C4A [extracellular region]
Stable Identifier
R-BTA-166731
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
extracellular region
Synonyms
C4A(1454-1744), E1BH06
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
Complement cascade (Bos taurus)
Activation of C3 and C5 (Bos taurus)
Activation of C5 (Bos taurus)
C5 convertases [plasma membrane] (Bos taurus)
C4b:C2a:C3b [plasma membrane] (Bos taurus)
Cell surface:C4b:C2a [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Cleavage of C3 by C3 convertases (Bos taurus)
C3 convertases [plasma membrane] (Bos taurus)
C4b:C2a:C3b [plasma membrane] (Bos taurus)
Cell surface:C4b:C2a [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Cell surface:C4b:C2a [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Formation of classic pathway C5 convertase (Bos taurus)
C4b:C2a:C3b [plasma membrane] (Bos taurus)
Cell surface:C4b:C2a [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Cell surface:C4b:C2a [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Initial triggering of complement (Bos taurus)
C4b binds to cell surface (Bos taurus)
C4b [extracellular region] (Bos taurus)
C4A(20-675):C4A(1454-1744):S-(L-isoglutamyl)-L-cysteine-C4A(757-1446) [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
C4B(1454-1744):C4B(20-675):S-(L-isoglutamyl)-L-cysteine-C4B(757-1446) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Formation of Classical C3 convertase (C4b:C2a complex) (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Cell surface:C4b:C2a [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Regulation of Complement cascade (Bos taurus)
C3 convertases spontaneously dissociate (Bos taurus)
C3 convertases [plasma membrane] (Bos taurus)
C4b:C2a:C3b [plasma membrane] (Bos taurus)
Cell surface:C4b:C2a [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Cell surface:C4b:C2a [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Cell surface:C4b:C2a [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
CD46 binds C4b (Bos taurus)
CD46:Cell surface:C4b [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
CD55 (DAF) binds C3bBb, C4bC2a (Bos taurus)
C4bC2a, C3bBb [plasma membrane] (Bos taurus)
Cell surface:C4b:C2a [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
CD55:C3 convertase complexes [plasma membrane] (Bos taurus)
CD55:C4bC2a [plasma membrane] (Bos taurus)
Cell surface:C4b:C2a [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Bos taurus)
CD55:C3 convertase complexes [plasma membrane] (Bos taurus)
CD55:C4bC2a [plasma membrane] (Bos taurus)
Cell surface:C4b:C2a [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
CD55:C4b [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Complement factor I binds to MCP, CR1:C4b, C3b (Bos taurus)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Bos taurus)
CD46:Cell surface:C4b [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Bos taurus)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Bos taurus)
CD46:Cell surface:C4b [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Factor I inactivates MCP/CR1-bound C4b/C3b (Bos taurus)
C4c, C3f [extracellular region] (Bos taurus)
C4c [extracellular region] (Bos taurus)
C4A-derived C4c [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
C4B-derived C4c [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Bos taurus)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Bos taurus)
CD46:Cell surface:C4b [plasma membrane] (Bos taurus)
Cell surface:C4b [plasma membrane] (Bos taurus)
C4b [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
Hydrolysis of internal thioester in C4b (Bos taurus)
C4b [extracellular region] (Bos taurus)
C4A(20-675):C4A(1454-1744):S-(L-isoglutamyl)-L-cysteine-C4A(757-1446) [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
C4B(1454-1744):C4B(20-675):S-(L-isoglutamyl)-L-cysteine-C4B(757-1446) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
C4b with hydrolysed thioester [extracellular region] (Bos taurus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Bos taurus)
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
deamidated-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4A [extracellular region] (Bos taurus)
External Reference Information
External Reference
UniProt:E1BH06
Gene Names
C4A
Reference Genes
ENSEMBL:ENSBTAG00000037533.3
UCSC:E1BH06 C4A
Other Identifiers
280678
Bt.4507.1.S1_at
GO:0002376
GO:0004866
GO:0005515
GO:0005576
GO:0005615
GO:0006954
GO:0006956
GO:0006958
GO:0030424
GO:0030425
GO:0042995
GO:0045087
GO:0045202
GO:0098542
GO:0098772
Participates
as a component of
deamidated-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
C4B-derived C4c [extracellular region] (Bos taurus)
C4B(1454-1744):C4B(20-675):S-(L-isoglutamyl)-L-cysteine-C4B(757-1446) [extracellular region] (Bos taurus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Bos taurus)
as a member of
Homologues of C4A(1454-1744) [extracellular region] (Bos taurus)
Other forms of this molecule
phospho-C4A [endoplasmic reticulum lumen]
C4A [endoplasmic reticulum lumen]
C4A [extracellular region]
C4A [extracellular region]
C4A [plasma membrane]
C4A [extracellular region]
C4A [extracellular region]
C4A [extracellular region]
C4A [extracellular region]
Inferred From
C4B(1454-1744) [extracellular region]
(Homo sapiens)
C4A(1454-1744) [extracellular region]
(Homo sapiens)
Cross References
ENSEMBL
ENSBTAT00000009019
,
ENSBTAP00000009019
,
ENSBTAG00000037533
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