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XPO1 [cytosol]
Stable Identifier
R-BTA-165539
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
XPO1, E1BE98
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle Checkpoints (Bos taurus)
Mitotic Spindle Checkpoint (Bos taurus)
Amplification of signal from the kinetochores (Bos taurus)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Bos taurus)
MAD2 associates with the Mad1 kinetochore complex (Bos taurus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
MAD2 converted to an inhibitory state via interaction with Mad1 (Bos taurus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Mad1 binds kinetochore (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Release of activated MAD2 from kinetochores (Bos taurus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Mad1:kinetochore complex [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Separation of Sister Chromatids (Bos taurus)
ESPL1 (Separase) cleaves centromeric cohesin (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Separation of sister chromatids (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Mitotic Prometaphase (Bos taurus)
EML4 and NUDC in mitotic spindle formation (Bos taurus)
EML4 recruits NUDC to mitotic spindle (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Kinetochore capture of astral microtubules (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Resolution of Sister Chromatid Cohesion (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Kinetochore assembly (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
PP2A-B56 dephosphorylates centromeric cohesin (Bos taurus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Phosphorylation of cohesin by PLK1 at centromeres (Bos taurus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Heme signaling (Bos taurus)
XPO1:BACH1:Hemes are transported out of the nucleus (Bos taurus)
XPO1:BACH1:Hemes [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Developmental Biology (Bos taurus)
MITF-M-regulated melanocyte development (Bos taurus)
Transcriptional and post-translational regulation of MITF-M expression and activity (Bos taurus)
XPO1-dependent export of p-S69,S73 MITF-M (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases Activate Formins (Bos taurus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Bos taurus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
CDC42:GTP recruits DIAPH2-2 to kinetochores (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
Signaling by WNT (Bos taurus)
TCF dependent signaling in response to WNT (Bos taurus)
Deactivation of the beta-catenin transactivating complex (Bos taurus)
YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Bos taurus)
XPO1:YWHAZ:p-S20-CBY1:CTNNB1 [cytosol] (Bos taurus)
XPO1 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:E1BE98
Gene Names
XPO1
Reference Genes
BioGPS Gene:510568 XPO1
ENSEMBL:ENSBTAG00000013254.6
ENSEMBL:ENSBTAG00000013254.7 XPO1
KEGG Gene (Bos taurus):510568 XPO1
Monarch:510568 XPO1
NCBI Gene:510568 XPO1
Reference Transcript
RefSeq:XM_005212773.3 XPO1
RefSeq:XM_015473481.1 XPO1
RefSeq:XM_005212772.3 XPO1
RefSeq:XM_005212771.3 XPO1
RefSeq:NM_001192261.1 XPO1
Other Identifiers
510568
GO:0000054
GO:0000055
GO:0000056
GO:0000776
GO:0005049
GO:0005634
GO:0005635
GO:0005642
GO:0005654
GO:0005694
GO:0005730
GO:0005737
GO:0005829
GO:0006406
GO:0006611
GO:0006886
GO:0006913
GO:0007010
GO:0010824
GO:0030163
GO:0031965
GO:0032434
GO:0032991
GO:0034504
GO:0042176
GO:0042254
GO:0043226
GO:0043231
GO:0046825
GO:0140104
GO:1990904
Participates
as an output of
XPO1-dependent export of p-S69,S73 MITF-M (Bos taurus)
as a component of
XPO1:BACH1:Hemes [cytosol] (Bos taurus)
XPO1:YWHAZ:p-S20-CBY1:CTNNB1 [cytosol] (Bos taurus)
Kinetochore [cytosol] (Bos taurus)
Other forms of this molecule
XPO1 [nucleoplasm]
Inferred From
XPO1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001179190.1
,
XP_005212830.1
,
XP_005212829.1
,
XP_005212828.1
,
XP_015328967.1
OpenTargets
ENSG00000082898
Ensembl
ENSBTAT00000017629
,
ENSBTAP00000017629
,
ENSBTAG00000013254
VGNC
36997
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