Reactome | REL [cytosol]

REL [cytosol]

Stable Identifier

R-BTA-1168579

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

REL, F1MJH6

Locations in the PathwayBrowser

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Immune System (Bos taurus)

- Adaptive Immune System (Bos taurus)
  - Signaling by the B Cell Receptor (BCR) (Bos taurus)
    - Downstream signaling events of B Cell Receptor (BCR) (Bos taurus)
      - Activation of NF-kappaB in B cells (Bos taurus)
        
        Activated IKK phosphorylates I-kappaB (Bos taurus)
        
        NF-kappa-B p50,p65,c-Rel:IKB [cytosol] (Bos taurus)
        
        NF-kappaB p50:c-Rel:IkB [cytosol] (Bos taurus)
        
        NF-kappaB p50:c-Rel [cytosol] (Bos taurus)
        
        REL [cytosol] (Bos taurus)
        
        NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Bos taurus)
        
        NF-kappaB p50:c-Rel:p-IKB [cytosol] (Bos taurus)
        
        NF-kappaB p50:c-Rel [cytosol] (Bos taurus)
        
        REL [cytosol] (Bos taurus)
        
        NF-kappaB translocates from the cytosol to the nucleus (Bos taurus)
        
        NF-kappaB p50,p65,c-Rel dimer [cytosol] (Bos taurus)
        
        NF-kappaB p50:c-Rel [cytosol] (Bos taurus)
        
        REL [cytosol] (Bos taurus)
        
        Ubiquitinated IkB is degraded (Bos taurus)
        
        NF-kappaB p50,p65,c-Rel dimer [cytosol] (Bos taurus)
        
        NF-kappaB p50:c-Rel [cytosol] (Bos taurus)
        
        REL [cytosol] (Bos taurus)
        
        NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Bos taurus)
        
        NF-kappaB p50:c-Rel:ub-p-IKB [cytosol] (Bos taurus)
        
        NF-kappaB p50:c-Rel [cytosol] (Bos taurus)
        
        REL [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:F1MJH6

Gene Names

REL

Reference Genes

BioGPS Gene:509135 REL

ENSEMBL:ENSBTAG00000015386.6

KEGG:bta:509135 REL

Monarch:509135 REL

NCBI Gene:509135 REL

UCSC:F1MJH6 REL

Reference Transcript

RefSeq:NM_001192970.1 REL

Other Identifiers

509135

GO:0000978

GO:0001228

GO:0003677

GO:0003700

GO:0005634

GO:0005737

GO:0006355

GO:0010629

GO:0032688

GO:0043123

GO:0045944

Participates

as a component of

NF-kappaB p50:c-Rel [cytosol] (Bos taurus)

Other forms of this molecule

REL [nucleoplasm]

Inferred From

REL [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001179899.1

ENSEMBL

ENSBTAP00000020447, ENSBTAG00000015386, ENSBTAT00000020447

VGNC

33857

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