Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
PRKACA [nucleoplasm]
Stable Identifier
R-BTA-111936
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
P00517
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
C-type lectin receptors (CLRs) (Bos taurus)
CD209 (DC-SIGN) signaling (Bos taurus)
Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit (Bos taurus)
RPS6KA5(MSK1/SAPK1):PKA catalytic subunits [nucleoplasm] (Bos taurus)
PRKACA [nucleoplasm] (Bos taurus)
Signal Transduction (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK6/MAPK4 signaling (Bos taurus)
PKA phosphorylates MAPKAPK5 (Bos taurus)
PRKACA [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:P00517
Reference Genes
BioGPS Gene:282322
ENSEMBL:ENSBTAG00000006642
KEGG:bta:282322
Monarch:282322
NCBI Gene:282322
UCSC:P00517
Reference Transcript
RefSeq:NM_174584.3
Other Identifiers
282322
Bt.4420.1.S1_at
GO:0000166
GO:0000287
GO:0001669
GO:0001707
GO:0001843
GO:0003824
GO:0004672
GO:0004674
GO:0004691
GO:0004712
GO:0005524
GO:0005634
GO:0005737
GO:0005739
GO:0005813
GO:0005815
GO:0005829
GO:0005886
GO:0005930
GO:0005952
GO:0006397
GO:0006468
GO:0006611
GO:0006886
GO:0006913
GO:0007189
GO:0007193
GO:0016020
GO:0016071
GO:0016301
GO:0016607
GO:0016740
GO:0019901
GO:0019904
GO:0021904
GO:0022414
GO:0030007
GO:0030145
GO:0031594
GO:0031625
GO:0031669
GO:0032024
GO:0034237
GO:0034605
GO:0036126
GO:0038110
GO:0038202
GO:0044853
GO:0045542
GO:0045667
GO:0045722
GO:0045879
GO:0046827
GO:0048240
GO:0048471
GO:0050766
GO:0050804
GO:0051726
GO:0061136
GO:0070417
GO:0070613
GO:0071333
GO:0071374
GO:0071377
GO:0097546
GO:0098794
GO:0098978
GO:0099170
GO:0106310
GO:0140096
GO:1904262
GO:1904539
GO:1990044
GO:2000810
Participates
as a member of
RPS6KA5(MSK1/SAPK1):PKA catalytic subunits [nucleoplasm] (Bos taurus)
Other forms of this molecule
PRKACA [cytosol]
PRKACA [ciliary base]
PRKACA [mitochondrial matrix]
Inferred From
Protein Kinase A, catalytic subunits [nucleoplasm]
(Homo sapiens)
PRKACA [nucleoplasm]
(Homo sapiens)
PRKACG [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_777009.1
ENSEMBL
ENSBTAT00000008727
,
ENSBTAG00000006642
,
ENSBTAP00000008727
IntEnz
2.7.11.11
ZINC - Substances
KAPCA_BOVIN
ZINC - Biogenic
KAPCA_BOVIN
ZINC target
P00517
PRO
P00517
VGNC
50250
ZINC - Predictions - Purchasable
KAPCA_BOVIN
PDB
9FQR
,
1Q8T
,
1Q8U
,
4YXR
,
3ZO3
,
4IJ9
,
8SF8
,
5VI9
,
2JDV
,
2UVZ
,
2UVY
,
1STC
,
2VO6
,
2UW0
,
4Z84
,
1XH9
,
1Q62
,
4C35
,
2GNH
,
2UZT
,
2UZU
,
4C37
,
4AXA
,
2UW3
,
9DW5
,
4C33
,
6E99
,
1YDT
,
1Q24
,
2OH0
,
4YXS
,
2UW4
,
9DW4
,
3DNE
,
1SZM
,
2UW6
,
1XH8
,
2GNG
,
1SVE
,
1XH4
,
1XH5
,
2F7E
,
3KKV
,
6E9L
,
2F7Z
,
2F7X
,
5VHB
,
1VEB
,
5VIB
,
1Q8W
,
1SMH
,
3ZO1
,
3BWJ
,
3ZO2
,
3ZO4
,
4Z83
,
2VO3
,
9DW9
,
2JDT
,
4C34
,
9DW8
,
4C36
,
2VO7
,
3DND
,
3E8C
,
1Q61
,
4C38
,
2VO0
,
3E8E
,
2VNW
,
9DW7
,
2UZV
,
2OJF
,
2VNY
,
1XHA
,
2UZW
,
1XH7
,
2UW5
,
1SVH
,
2JDS
,
1XH6
,
2GNF
,
2UW8
,
1SVG
,
2C1A
,
2UW7
,
2GNL
,
1YDS
,
2C1B
,
4IE9
,
2UVX
,
2GNJ
,
1YDR
,
2GFC
,
3AG9
,
2GNI
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text