Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
(3Fe-4S)(1+) [mitochondrial matrix]
Stable Identifier
R-ALL-9854362
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
Fe3S4 iron-sulfur cluster
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Citric acid cycle (TCA cycle) (Bos taurus)
ACO2 isomerizes citrate (Bos taurus)
ACO2:3Fe-4S [mitochondrial matrix] (Bos taurus)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Bos taurus)
Frataxin transfers Fe2+ to ACO2 (Bos taurus)
ACO2:3Fe-4S [mitochondrial matrix] (Bos taurus)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Bos taurus)
ACO2:3Fe-4S [mitochondrial matrix] (Bos taurus)
(3Fe-4S)(1+) [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Citric acid cycle (TCA cycle) (Caenorhabditis elegans)
ACO2 isomerizes citrate (Caenorhabditis elegans)
ACO2:3Fe-4S [mitochondrial matrix] (Caenorhabditis elegans)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Caenorhabditis elegans)
Frataxin transfers Fe2+ to ACO2 (Caenorhabditis elegans)
ACO2:3Fe-4S [mitochondrial matrix] (Caenorhabditis elegans)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Caenorhabditis elegans)
ACO2:3Fe-4S [mitochondrial matrix] (Caenorhabditis elegans)
(3Fe-4S)(1+) [mitochondrial matrix]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Citric acid cycle (TCA cycle) (Canis familiaris)
ACO2 isomerizes citrate (Canis familiaris)
ACO2:3Fe-4S [mitochondrial matrix] (Canis familiaris)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Canis familiaris)
Frataxin transfers Fe2+ to ACO2 (Canis familiaris)
ACO2:3Fe-4S [mitochondrial matrix] (Canis familiaris)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Canis familiaris)
ACO2:3Fe-4S [mitochondrial matrix] (Canis familiaris)
(3Fe-4S)(1+) [mitochondrial matrix]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Citric acid cycle (TCA cycle) (Danio rerio)
ACO2 isomerizes citrate (Danio rerio)
ACO2:3Fe-4S [mitochondrial matrix] (Danio rerio)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Danio rerio)
Frataxin transfers Fe2+ to ACO2 (Danio rerio)
ACO2:3Fe-4S [mitochondrial matrix] (Danio rerio)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Danio rerio)
ACO2:3Fe-4S [mitochondrial matrix] (Danio rerio)
(3Fe-4S)(1+) [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Aerobic respiration and respiratory electron transport (Dictyostelium discoideum)
Citric acid cycle (TCA cycle) (Dictyostelium discoideum)
ACO2 isomerizes citrate (Dictyostelium discoideum)
ACO2:3Fe-4S [mitochondrial matrix] (Dictyostelium discoideum)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Dictyostelium discoideum)
Frataxin transfers Fe2+ to ACO2 (Dictyostelium discoideum)
ACO2:3Fe-4S [mitochondrial matrix] (Dictyostelium discoideum)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Dictyostelium discoideum)
ACO2:3Fe-4S [mitochondrial matrix] (Dictyostelium discoideum)
(3Fe-4S)(1+) [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Citric acid cycle (TCA cycle) (Drosophila melanogaster)
ACO2 isomerizes citrate (Drosophila melanogaster)
ACO2:3Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Drosophila melanogaster)
Frataxin transfers Fe2+ to ACO2 (Drosophila melanogaster)
ACO2:3Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Drosophila melanogaster)
ACO2:3Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
(3Fe-4S)(1+) [mitochondrial matrix]
Metabolism (Gallus gallus)
Aerobic respiration and respiratory electron transport (Gallus gallus)
Citric acid cycle (TCA cycle) (Gallus gallus)
ACO2 isomerizes citrate (Gallus gallus)
ACO2:3Fe-4S [mitochondrial matrix] (Gallus gallus)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Gallus gallus)
Frataxin transfers Fe2+ to ACO2 (Gallus gallus)
ACO2:3Fe-4S [mitochondrial matrix] (Gallus gallus)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Gallus gallus)
ACO2:3Fe-4S [mitochondrial matrix] (Gallus gallus)
(3Fe-4S)(1+) [mitochondrial matrix]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
ACO2 isomerizes citrate (Homo sapiens)
ACO2:3Fe-4S [mitochondrial matrix] (Homo sapiens)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Homo sapiens)
Frataxin transfers Fe2+ to ACO2 (Homo sapiens)
ACO2:3Fe-4S [mitochondrial matrix] (Homo sapiens)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Homo sapiens)
ACO2:3Fe-4S [mitochondrial matrix] (Homo sapiens)
(3Fe-4S)(1+) [mitochondrial matrix]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Citric acid cycle (TCA cycle) (Mus musculus)
ACO2 isomerizes citrate (Mus musculus)
ACO2:3Fe-4S [mitochondrial matrix] (Mus musculus)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Mus musculus)
Frataxin transfers Fe2+ to ACO2 (Mus musculus)
ACO2:3Fe-4S [mitochondrial matrix] (Mus musculus)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Mus musculus)
ACO2:3Fe-4S [mitochondrial matrix] (Mus musculus)
(3Fe-4S)(1+) [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Citric acid cycle (TCA cycle) (Rattus norvegicus)
ACO2 isomerizes citrate (Rattus norvegicus)
ACO2:3Fe-4S [mitochondrial matrix] (Rattus norvegicus)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Rattus norvegicus)
Frataxin transfers Fe2+ to ACO2 (Rattus norvegicus)
ACO2:3Fe-4S [mitochondrial matrix] (Rattus norvegicus)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Rattus norvegicus)
ACO2:3Fe-4S [mitochondrial matrix] (Rattus norvegicus)
(3Fe-4S)(1+) [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Aerobic respiration and respiratory electron transport (Saccharomyces cerevisiae)
Citric acid cycle (TCA cycle) (Saccharomyces cerevisiae)
ACO2 isomerizes citrate (Saccharomyces cerevisiae)
ACO2:3Fe-4S [mitochondrial matrix] (Saccharomyces cerevisiae)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Saccharomyces cerevisiae)
Frataxin transfers Fe2+ to ACO2 (Saccharomyces cerevisiae)
ACO2:3Fe-4S [mitochondrial matrix] (Saccharomyces cerevisiae)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Saccharomyces cerevisiae)
ACO2:3Fe-4S [mitochondrial matrix] (Saccharomyces cerevisiae)
(3Fe-4S)(1+) [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Aerobic respiration and respiratory electron transport (Schizosaccharomyces pombe)
Citric acid cycle (TCA cycle) (Schizosaccharomyces pombe)
ACO2 isomerizes citrate (Schizosaccharomyces pombe)
ACO2:3Fe-4S [mitochondrial matrix] (Schizosaccharomyces pombe)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Schizosaccharomyces pombe)
Frataxin transfers Fe2+ to ACO2 (Schizosaccharomyces pombe)
ACO2:3Fe-4S [mitochondrial matrix] (Schizosaccharomyces pombe)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Schizosaccharomyces pombe)
ACO2:3Fe-4S [mitochondrial matrix] (Schizosaccharomyces pombe)
(3Fe-4S)(1+) [mitochondrial matrix]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Citric acid cycle (TCA cycle) (Sus scrofa)
ACO2 isomerizes citrate (Sus scrofa)
ACO2:3Fe-4S [mitochondrial matrix] (Sus scrofa)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Sus scrofa)
Frataxin transfers Fe2+ to ACO2 (Sus scrofa)
ACO2:3Fe-4S [mitochondrial matrix] (Sus scrofa)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Sus scrofa)
ACO2:3Fe-4S [mitochondrial matrix] (Sus scrofa)
(3Fe-4S)(1+) [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Citric acid cycle (TCA cycle) (Xenopus tropicalis)
ACO2 isomerizes citrate (Xenopus tropicalis)
ACO2:3Fe-4S [mitochondrial matrix] (Xenopus tropicalis)
(3Fe-4S)(1+) [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Xenopus tropicalis)
Frataxin transfers Fe2+ to ACO2 (Xenopus tropicalis)
ACO2:3Fe-4S [mitochondrial matrix] (Xenopus tropicalis)
(3Fe-4S)(1+) [mitochondrial matrix]
ROS,RNS oxidize ACO2:4Fe-4S (Xenopus tropicalis)
ACO2:3Fe-4S [mitochondrial matrix] (Xenopus tropicalis)
(3Fe-4S)(1+) [mitochondrial matrix]
External Reference Information
External Reference
Fe3S4 iron-sulfur cluster [ChEBI:64606]
Participates
as a component of
ACO2:3Fe-4S [mitochondrial matrix] (Schizosaccharomyces pombe)
ACO2:3Fe-4S [mitochondrial matrix] (Sus scrofa)
ACO2:3Fe-4S [mitochondrial matrix] (Dictyostelium discoideum)
ACO2:3Fe-4S [mitochondrial matrix] (Xenopus tropicalis)
ACO2:3Fe-4S [mitochondrial matrix] (Canis familiaris)
ACO2:3Fe-4S [mitochondrial matrix] (Danio rerio)
ACO2:3Fe-4S [mitochondrial matrix] (Bos taurus)
ACO2:3Fe-4S [mitochondrial matrix] (Drosophila melanogaster)
ACO2:3Fe-4S [mitochondrial matrix] (Saccharomyces cerevisiae)
ACO2:3Fe-4S [mitochondrial matrix] (Gallus gallus)
ACO2:3Fe-4S [mitochondrial matrix] (Mus musculus)
ACO2:3Fe-4S [mitochondrial matrix] (Caenorhabditis elegans)
ACO2:3Fe-4S [mitochondrial matrix] (Rattus norvegicus)
ACO2:3Fe-4S [mitochondrial matrix] (Homo sapiens)
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
