Reactome | cinacalcet [extracellular region]

cinacalcet [extracellular region]

Stable Identifier

R-ALL-9703891

Type

ChemicalDrug

Compartment

extracellular region

Locations in the PathwayBrowser

for Species:

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Canis familiaris)
      - CASR binds CASR agonists (Canis familiaris)
        
        CASR agonists [extracellular region]
        
        cinacalcet [extracellular region]
        
        CASR:CASR agonists [plasma membrane] (Canis familiaris)
        
        CASR agonists [extracellular region]
        
        cinacalcet [extracellular region]

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Rattus norvegicus)
      - CASR binds CASR agonists (Rattus norvegicus)
        
        CASR agonists [extracellular region]
        
        cinacalcet [extracellular region]
        
        CASR:CASR agonists [plasma membrane] (Rattus norvegicus)
        
        CASR agonists [extracellular region]
        
        cinacalcet [extracellular region]

Signal Transduction (Xenopus tropicalis)

- Signaling by GPCR (Xenopus tropicalis)
  - GPCR ligand binding (Xenopus tropicalis)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Xenopus tropicalis)
      - CASR binds CASR agonists (Xenopus tropicalis)
        
        CASR agonists [extracellular region]
        
        cinacalcet [extracellular region]
        
        CASR:CASR agonists [plasma membrane] (Xenopus tropicalis)
        
        CASR agonists [extracellular region]
        
        cinacalcet [extracellular region]

External Reference Information

External Reference

cinacalcet [Guide to Pharmacology:3308]

Participates

as a member of

CASR agonists [extracellular region]

Disease

Name	Identifier	Synonyms
secondary hyperparathyroidism	DOID:12466

Cross References

Mondo

0006964

ChEBI

48390

Pharos - Ligands

QVAZDS6A5DRX

PharmacoDB

PDBC02823

© 2026 Reactome

Cite Us!