Reactome | fremanezumab [extracellular region]

fremanezumab [extracellular region]

Stable Identifier

R-ALL-9702389

Type

ProteinDrug

Compartment

extracellular region

Locations in the PathwayBrowser

for Species:

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class B/2 (Secretin family receptors) (Canis familiaris)
      - Calcitonin-like ligand receptors (Canis familiaris)
        
        CALCA(83-119) binds CALCA antibodies (Canis familiaris)
        
        CALCA antibodies [extracellular region]
        
        fremanezumab [extracellular region]
        
        CALCA(83-119):CALCA antibodies [extracellular region] (Canis familiaris)
        
        CALCA antibodies [extracellular region]
        
        fremanezumab [extracellular region]

Signal Transduction (Gallus gallus)

- Signaling by GPCR (Gallus gallus)
  - GPCR ligand binding (Gallus gallus)
    - Class B/2 (Secretin family receptors) (Gallus gallus)
      - Calcitonin-like ligand receptors (Gallus gallus)
        
        CALCA(83-119) binds CALCA antibodies (Gallus gallus)
        
        CALCA antibodies [extracellular region]
        
        fremanezumab [extracellular region]
        
        CALCA(83-119):CALCA antibodies [extracellular region] (Gallus gallus)
        
        CALCA antibodies [extracellular region]
        
        fremanezumab [extracellular region]

Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR ligand binding (Homo sapiens)
    - Class B/2 (Secretin family receptors) (Homo sapiens)
      - Calcitonin-like ligand receptors (Homo sapiens)
        
        CALCA(83-119) binds CALCA antibodies (Homo sapiens)
        
        CALCA antibodies [extracellular region]
        
        fremanezumab [extracellular region]
        
        CALCA(83-119):CALCA antibodies [extracellular region] (Homo sapiens)
        
        CALCA antibodies [extracellular region]
        
        fremanezumab [extracellular region]

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class B/2 (Secretin family receptors) (Mus musculus)
      - Calcitonin-like ligand receptors (Mus musculus)
        
        CALCA(83-119) binds CALCA antibodies (Mus musculus)
        
        CALCA antibodies [extracellular region]
        
        fremanezumab [extracellular region]
        
        CALCA(83-119):CALCA antibodies [extracellular region] (Mus musculus)
        
        CALCA antibodies [extracellular region]
        
        fremanezumab [extracellular region]

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class B/2 (Secretin family receptors) (Rattus norvegicus)
      - Calcitonin-like ligand receptors (Rattus norvegicus)
        
        CALCA(83-119) binds CALCA antibodies (Rattus norvegicus)
        
        CALCA antibodies [extracellular region]
        
        fremanezumab [extracellular region]
        
        CALCA(83-119):CALCA antibodies [extracellular region] (Rattus norvegicus)
        
        CALCA antibodies [extracellular region]
        
        fremanezumab [extracellular region]

Signal Transduction (Xenopus tropicalis)

- Signaling by GPCR (Xenopus tropicalis)
  - GPCR ligand binding (Xenopus tropicalis)
    - Class B/2 (Secretin family receptors) (Xenopus tropicalis)
      - Calcitonin-like ligand receptors (Xenopus tropicalis)
        
        CALCA(83-119) binds CALCA antibodies (Xenopus tropicalis)
        
        CALCA antibodies [extracellular region]
        
        fremanezumab [extracellular region]
        
        CALCA(83-119):CALCA antibodies [extracellular region] (Xenopus tropicalis)
        
        CALCA antibodies [extracellular region]
        
        fremanezumab [extracellular region]

External Reference Information

External Reference

fremanezumab [Guide to Pharmacology:9208]

Participates

as a member of

CALCA antibodies [extracellular region]

Disease

Name	Identifier	Synonyms
migraine	DOID:6364	migraine variant, migraine disorder, migraine with or without aura

Cross References

Mondo

0005277

© 2026 Reactome

Cite Us!