pimasertib [cytosol]

Stable Identifier
R-ALL-9657523
Type
ChemicalDrug
Compartment
cytosol
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Literature References
PubMed ID Title Journal Year
21118963 MEK1/2 inhibitors AS703026 and AZD6244 may be potential therapies for KRAS mutated colorectal cancer that is resistant to EGFR monoclonal antibody therapy

Yoon, J, Koo, KH, Choi, KY

Cancer Res. 2011
20331454 Blockade of the MEK/ERK signalling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti-myeloma activity in vitro and in vivo

Kim, K, Kong, SY, Fulciniti, M, Li, X, Song, W, Nahar, S, Burger, P, Rumizen, MJ, Podar, K, Chauhan, D, Hideshima, T, Munshi, NC, Richardson, P, Clark, A, Ogden, J, Goutopoulos, A, Rastelli, L, Anderson, KC, Tai, YT

Br. J. Haematol. 2010
External Reference Information
External Reference
pimasertib [Guide to Pharmacology:7872]
Participates
as a candidate of
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
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ChEBI
PharmacoDB
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