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haloperidol [extracellular region]
Stable Identifier
R-ALL-9654039
Type
ChemicalDrug
Compartment
extracellular region
Synonyms
Haldol®, MCN-JR-1625, R-1625, Serenace®
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Sensory Perception (Bos taurus)
Sensory perception of taste (Bos taurus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Bos taurus)
Bitter compound binds bitter taste receptor (TAS2R) (Bos taurus)
Ligand of TAS2R (non-orphan) [extracellular region]
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
TAS2R (non-orphan):ligand [plasma membrane] (Bos taurus)
TAS2R10:ligand [plasma membrane] (Bos taurus)
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
TAS2R14:ligand [plasma membrane] (Bos taurus)
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR ligand binding (Bos taurus)
Class A/1 (Rhodopsin-like receptors) (Bos taurus)
Amine ligand-binding receptors (Bos taurus)
Dopamine receptors (Bos taurus)
DRD2 antagonist drugs bind to DRD2 (Bos taurus)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
DRD2:DRD2 antagonists [plasma membrane] (Bos taurus)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
Serotonin receptors (Bos taurus)
HTR1A binds HTR1A antagonists (Bos taurus)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
HTR1A:HTR1A Antagonist drugs [plasma membrane] (Bos taurus)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
Signal Transduction (Caenorhabditis elegans)
Signaling by GPCR (Caenorhabditis elegans)
GPCR ligand binding (Caenorhabditis elegans)
Class A/1 (Rhodopsin-like receptors) (Caenorhabditis elegans)
Amine ligand-binding receptors (Caenorhabditis elegans)
Dopamine receptors (Caenorhabditis elegans)
DRD2 antagonist drugs bind to DRD2 (Caenorhabditis elegans)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
DRD2:DRD2 antagonists [plasma membrane] (Caenorhabditis elegans)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
Histamine receptors (Caenorhabditis elegans)
HRH1 binds HRH1 inverse agonists (Caenorhabditis elegans)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
HRH1:HRH1 inverse agonists [plasma membrane] (Caenorhabditis elegans)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
Serotonin receptors (Caenorhabditis elegans)
HTR1A binds HTR1A antagonists (Caenorhabditis elegans)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
HTR1A:HTR1A Antagonist drugs [plasma membrane] (Caenorhabditis elegans)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
Sensory Perception (Canis familiaris)
Sensory perception of taste (Canis familiaris)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Canis familiaris)
Bitter compound binds bitter taste receptor (TAS2R) (Canis familiaris)
Ligand of TAS2R (non-orphan) [extracellular region]
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
TAS2R (non-orphan):ligand [plasma membrane] (Canis familiaris)
TAS2R10:ligand [plasma membrane] (Canis familiaris)
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
Signal Transduction (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR ligand binding (Canis familiaris)
Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
Amine ligand-binding receptors (Canis familiaris)
Dopamine receptors (Canis familiaris)
DRD2 antagonist drugs bind to DRD2 (Canis familiaris)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
DRD2:DRD2 antagonists [plasma membrane] (Canis familiaris)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
Histamine receptors (Canis familiaris)
HRH1 binds HRH1 inverse agonists (Canis familiaris)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
HRH1:HRH1 inverse agonists [plasma membrane] (Canis familiaris)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
Serotonin receptors (Canis familiaris)
HTR1A binds HTR1A antagonists (Canis familiaris)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
HTR1A:HTR1A Antagonist drugs [plasma membrane] (Canis familiaris)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
Sensory Perception (Danio rerio)
Sensory perception of taste (Danio rerio)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Danio rerio)
Bitter compound binds bitter taste receptor (TAS2R) (Danio rerio)
Ligand of TAS2R (non-orphan) [extracellular region]
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
TAS2R (non-orphan):ligand [plasma membrane] (Danio rerio)
TAS2R10:ligand [plasma membrane] (Danio rerio)
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
TAS2R14:ligand [plasma membrane] (Danio rerio)
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
Signal Transduction (Danio rerio)
Signaling by GPCR (Danio rerio)
GPCR ligand binding (Danio rerio)
Class A/1 (Rhodopsin-like receptors) (Danio rerio)
Amine ligand-binding receptors (Danio rerio)
Dopamine receptors (Danio rerio)
DRD2 antagonist drugs bind to DRD2 (Danio rerio)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
DRD2:DRD2 antagonists [plasma membrane] (Danio rerio)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
Serotonin receptors (Danio rerio)
HTR1A binds HTR1A antagonists (Danio rerio)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
HTR1A:HTR1A Antagonist drugs [plasma membrane] (Danio rerio)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
Signal Transduction (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR ligand binding (Drosophila melanogaster)
Class A/1 (Rhodopsin-like receptors) (Drosophila melanogaster)
Amine ligand-binding receptors (Drosophila melanogaster)
Dopamine receptors (Drosophila melanogaster)
DRD2 antagonist drugs bind to DRD2 (Drosophila melanogaster)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
DRD2:DRD2 antagonists [plasma membrane] (Drosophila melanogaster)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
Serotonin receptors (Drosophila melanogaster)
HTR1A binds HTR1A antagonists (Drosophila melanogaster)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
HTR1A:HTR1A Antagonist drugs [plasma membrane] (Drosophila melanogaster)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
Sensory Perception (Gallus gallus)
Sensory perception of taste (Gallus gallus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Gallus gallus)
Bitter compound binds bitter taste receptor (TAS2R) (Gallus gallus)
Ligand of TAS2R (non-orphan) [extracellular region]
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Gallus gallus)
TAS2R (non-orphan):ligand [plasma membrane] (Gallus gallus)
TAS2R10:ligand [plasma membrane] (Gallus gallus)
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
TAS2R14:ligand [plasma membrane] (Gallus gallus)
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
Signal Transduction (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR ligand binding (Gallus gallus)
Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
Amine ligand-binding receptors (Gallus gallus)
Dopamine receptors (Gallus gallus)
DRD2 antagonist drugs bind to DRD2 (Gallus gallus)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
DRD2:DRD2 antagonists [plasma membrane] (Gallus gallus)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
Histamine receptors (Gallus gallus)
HRH1 binds HRH1 inverse agonists (Gallus gallus)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
HRH1:HRH1 inverse agonists [plasma membrane] (Gallus gallus)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
Serotonin receptors (Gallus gallus)
HTR1A binds HTR1A antagonists (Gallus gallus)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
HTR1A:HTR1A Antagonist drugs [plasma membrane] (Gallus gallus)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
Sensory Perception (Homo sapiens)
Sensory perception of taste (Homo sapiens)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Homo sapiens)
Bitter compound binds bitter taste receptor (TAS2R) (Homo sapiens)
Ligand of TAS2R (non-orphan) [extracellular region]
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS2R (non-orphan):ligand [plasma membrane] (Homo sapiens)
TAS2R10:ligand [plasma membrane] (Homo sapiens)
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
TAS2R14:ligand [plasma membrane] (Homo sapiens)
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS2R (non-orphan):ligand [plasma membrane] (Homo sapiens)
TAS2R10:ligand [plasma membrane] (Homo sapiens)
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
TAS2R14:ligand [plasma membrane] (Homo sapiens)
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
TAS2R:ligand:GNAT3:GTP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS2R (non-orphan):ligand [plasma membrane] (Homo sapiens)
TAS2R10:ligand [plasma membrane] (Homo sapiens)
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
TAS2R14:ligand [plasma membrane] (Homo sapiens)
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding (Homo sapiens)
TAS2R (non-orphan):ligand [plasma membrane] (Homo sapiens)
TAS2R10:ligand [plasma membrane] (Homo sapiens)
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
TAS2R14:ligand [plasma membrane] (Homo sapiens)
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
TAS2R:ligand:GNAT3:GTP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS2R (non-orphan):ligand [plasma membrane] (Homo sapiens)
TAS2R10:ligand [plasma membrane] (Homo sapiens)
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
TAS2R14:ligand [plasma membrane] (Homo sapiens)
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Amine ligand-binding receptors (Homo sapiens)
Dopamine receptors (Homo sapiens)
DRD2 antagonist drugs bind to DRD2 (Homo sapiens)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
DRD2:DRD2 antagonists [plasma membrane] (Homo sapiens)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
Histamine receptors (Homo sapiens)
HRH1 binds HRH1 inverse agonists (Homo sapiens)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
HRH1:HRH1 inverse agonists [plasma membrane] (Homo sapiens)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
Serotonin receptors (Homo sapiens)
HTR1A binds HTR1A antagonists (Homo sapiens)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
HTR1A:HTR1A Antagonist drugs [plasma membrane] (Homo sapiens)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
Sensory Perception (Mus musculus)
Sensory perception of taste (Mus musculus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Mus musculus)
Bitter compound binds bitter taste receptor (TAS2R) (Mus musculus)
Ligand of TAS2R (non-orphan) [extracellular region]
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
TAS2R (non-orphan):ligand [plasma membrane] (Mus musculus)
TAS2R10:ligand [plasma membrane] (Mus musculus)
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
TAS2R14:ligand [plasma membrane] (Mus musculus)
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR ligand binding (Mus musculus)
Class A/1 (Rhodopsin-like receptors) (Mus musculus)
Amine ligand-binding receptors (Mus musculus)
Dopamine receptors (Mus musculus)
DRD2 antagonist drugs bind to DRD2 (Mus musculus)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
DRD2:DRD2 antagonists [plasma membrane] (Mus musculus)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
Histamine receptors (Mus musculus)
HRH1 binds HRH1 inverse agonists (Mus musculus)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
HRH1:HRH1 inverse agonists [plasma membrane] (Mus musculus)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
Serotonin receptors (Mus musculus)
HTR1A binds HTR1A antagonists (Mus musculus)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
HTR1A:HTR1A Antagonist drugs [plasma membrane] (Mus musculus)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
Sensory Perception (Rattus norvegicus)
Sensory perception of taste (Rattus norvegicus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Rattus norvegicus)
Bitter compound binds bitter taste receptor (TAS2R) (Rattus norvegicus)
Ligand of TAS2R (non-orphan) [extracellular region]
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Rattus norvegicus)
TAS2R (non-orphan):ligand [plasma membrane] (Rattus norvegicus)
TAS2R10:ligand [plasma membrane] (Rattus norvegicus)
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
TAS2R14:ligand [plasma membrane] (Rattus norvegicus)
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
Signal Transduction (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR ligand binding (Rattus norvegicus)
Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
Amine ligand-binding receptors (Rattus norvegicus)
Dopamine receptors (Rattus norvegicus)
DRD2 antagonist drugs bind to DRD2 (Rattus norvegicus)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
DRD2:DRD2 antagonists [plasma membrane] (Rattus norvegicus)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
Histamine receptors (Rattus norvegicus)
HRH1 binds HRH1 inverse agonists (Rattus norvegicus)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
HRH1:HRH1 inverse agonists [plasma membrane] (Rattus norvegicus)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
Serotonin receptors (Rattus norvegicus)
HTR1A binds HTR1A antagonists (Rattus norvegicus)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
HTR1A:HTR1A Antagonist drugs [plasma membrane] (Rattus norvegicus)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
Sensory Perception (Sus scrofa)
Sensory perception of taste (Sus scrofa)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Sus scrofa)
Bitter compound binds bitter taste receptor (TAS2R) (Sus scrofa)
Ligand of TAS2R (non-orphan) [extracellular region]
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Sus scrofa)
TAS2R (non-orphan):ligand [plasma membrane] (Sus scrofa)
TAS2R10:ligand [plasma membrane] (Sus scrofa)
Ligand of TAS2R10 [extracellular region]
haloperidol [extracellular region]
TAS2R14:ligand [plasma membrane] (Sus scrofa)
Ligand of TAS2R14 [extracellular region]
haloperidol [extracellular region]
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR ligand binding (Sus scrofa)
Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
Amine ligand-binding receptors (Sus scrofa)
Dopamine receptors (Sus scrofa)
DRD2 antagonist drugs bind to DRD2 (Sus scrofa)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
DRD2:DRD2 antagonists [plasma membrane] (Sus scrofa)
DRD2 antagonists [extracellular region]
haloperidol [extracellular region]
Histamine receptors (Sus scrofa)
HRH1 binds HRH1 inverse agonists (Sus scrofa)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
HRH1:HRH1 inverse agonists [plasma membrane] (Sus scrofa)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
Signal Transduction (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR ligand binding (Xenopus tropicalis)
Class A/1 (Rhodopsin-like receptors) (Xenopus tropicalis)
Amine ligand-binding receptors (Xenopus tropicalis)
Histamine receptors (Xenopus tropicalis)
HRH1 binds HRH1 inverse agonists (Xenopus tropicalis)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
HRH1:HRH1 inverse agonists [plasma membrane] (Xenopus tropicalis)
HRH1 inverse agonists [extracellular region]
haloperidol [extracellular region]
Serotonin receptors (Xenopus tropicalis)
HTR1A binds HTR1A antagonists (Xenopus tropicalis)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
HTR1A:HTR1A Antagonist drugs [plasma membrane] (Xenopus tropicalis)
HTR1A antagonists [extracellular region]
haloperidol [extracellular region]
External Reference Information
External Reference
haloperidol [Guide to Pharmacology:86]
Participates
as a member of
Ligand of TAS2R14 [extracellular region]
Ligand of TAS2R10 [extracellular region]
HTR1A antagonists [extracellular region]
HRH1 inverse agonists [extracellular region]
DRD2 antagonists [extracellular region]
Disease
Name
Identifier
Synonyms
psychotic disorder
DOID:2468
mental or behavioural disorder
schizophrenia
DOID:5419
schizophrenia-1
Gilles de la Tourette syndrome
DOID:11119
Psychogenic tics, Guinon's disease, Tourette syndrome, motor-verbal tic disorder
Cross References
Pharos - Ligands
GKRULT6FAR97
PharmacoDB
PDBC00577
PubChem Compound
135650345
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