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felodipine [extracellular region]
Stable Identifier
R-ALL-9614123
Type
ChemicalDrug
Compartment
extracellular region
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Muscle contraction (Bos taurus)
Cardiac conduction (Bos taurus)
Phase 2 - plateau phase (Bos taurus)
Class IV antihypertensives bind LTCC multimer (Bos taurus)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Bos taurus)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Smooth Muscle Contraction (Bos taurus)
T-type VDCC bind T-type VDCC blockers (Bos taurus)
T-type VDCC blockers [extracellular region]
felodipine [extracellular region]
T-type VDCC:T-type VDCC blockers [plasma membrane] (Bos taurus)
T-type VDCC blockers [extracellular region]
felodipine [extracellular region]
Muscle contraction (Caenorhabditis elegans)
Cardiac conduction (Caenorhabditis elegans)
Phase 2 - plateau phase (Caenorhabditis elegans)
Class IV antihypertensives bind LTCC multimer (Caenorhabditis elegans)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Caenorhabditis elegans)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Muscle contraction (Canis familiaris)
Cardiac conduction (Canis familiaris)
Phase 2 - plateau phase (Canis familiaris)
Class IV antihypertensives bind LTCC multimer (Canis familiaris)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Canis familiaris)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Muscle contraction (Drosophila melanogaster)
Cardiac conduction (Drosophila melanogaster)
Phase 2 - plateau phase (Drosophila melanogaster)
Class IV antihypertensives bind LTCC multimer (Drosophila melanogaster)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Drosophila melanogaster)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Muscle contraction (Gallus gallus)
Cardiac conduction (Gallus gallus)
Phase 2 - plateau phase (Gallus gallus)
Class IV antihypertensives bind LTCC multimer (Gallus gallus)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Gallus gallus)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Phase 2 - plateau phase (Homo sapiens)
Class IV antihypertensives bind LTCC multimer (Homo sapiens)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Homo sapiens)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Smooth Muscle Contraction (Homo sapiens)
T-type VDCC bind T-type VDCC blockers (Homo sapiens)
T-type VDCC blockers [extracellular region]
felodipine [extracellular region]
T-type VDCC:T-type VDCC blockers [plasma membrane] (Homo sapiens)
T-type VDCC blockers [extracellular region]
felodipine [extracellular region]
Muscle contraction (Mus musculus)
Cardiac conduction (Mus musculus)
Phase 2 - plateau phase (Mus musculus)
Class IV antihypertensives bind LTCC multimer (Mus musculus)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Mus musculus)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Muscle contraction (Rattus norvegicus)
Cardiac conduction (Rattus norvegicus)
Phase 2 - plateau phase (Rattus norvegicus)
Class IV antihypertensives bind LTCC multimer (Rattus norvegicus)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Rattus norvegicus)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Muscle contraction (Saccharomyces cerevisiae)
Smooth Muscle Contraction (Saccharomyces cerevisiae)
T-type VDCC bind T-type VDCC blockers (Saccharomyces cerevisiae)
T-type VDCC blockers [extracellular region]
felodipine [extracellular region]
T-type VDCC:T-type VDCC blockers [plasma membrane] (Saccharomyces cerevisiae)
T-type VDCC blockers [extracellular region]
felodipine [extracellular region]
Muscle contraction (Schizosaccharomyces pombe)
Smooth Muscle Contraction (Schizosaccharomyces pombe)
T-type VDCC bind T-type VDCC blockers (Schizosaccharomyces pombe)
T-type VDCC blockers [extracellular region]
felodipine [extracellular region]
T-type VDCC:T-type VDCC blockers [plasma membrane] (Schizosaccharomyces pombe)
T-type VDCC blockers [extracellular region]
felodipine [extracellular region]
Muscle contraction (Sus scrofa)
Cardiac conduction (Sus scrofa)
Phase 2 - plateau phase (Sus scrofa)
Class IV antihypertensives bind LTCC multimer (Sus scrofa)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Sus scrofa)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Smooth Muscle Contraction (Sus scrofa)
T-type VDCC bind T-type VDCC blockers (Sus scrofa)
T-type VDCC blockers [extracellular region]
felodipine [extracellular region]
T-type VDCC:T-type VDCC blockers [plasma membrane] (Sus scrofa)
T-type VDCC blockers [extracellular region]
felodipine [extracellular region]
Muscle contraction (Xenopus tropicalis)
Cardiac conduction (Xenopus tropicalis)
Phase 2 - plateau phase (Xenopus tropicalis)
Class IV antihypertensives bind LTCC multimer (Xenopus tropicalis)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Xenopus tropicalis)
Class IV antihypertensives [extracellular region]
felodipine [extracellular region]
Literature References
PubMed ID
Title
Journal
Year
9916609
Amlodipine, felodipine, and isradipine in the treatment of Chinese patients with mild-to-moderate hypertension
Wu, BZ
,
Cheung, BM
,
Lau, CP
Clin Ther
1998
3327673
The use of felodipine in the treatment of severe hypertension
Wathen, CG
,
Muir, AL
Drugs
1987
8458178
Felodipine and isradipine: new calcium-channel-blocking agents for the treatment of hypertension
Walton, T
,
Symes, LR
Clin Pharm
1993
External Reference Information
External Reference
felodipine [Guide to Pharmacology:4190]
Participates
as a member of
Class IV antihypertensives [extracellular region]
T-type VDCC blockers [extracellular region]
Disease
Name
Identifier
Synonyms
intermediate coronary syndrome
DOID:8805
Unstable angina, Angina at rest, Worsening angina, Impending infarction, Preinfarction angina, Anginal chest pain at rest
hypertension
DOID:10763
High blood pressure (& [essential hypertension]), HTN, hypertensive disease, hyperpiesia, vascular hypertensive disorder
Cross References
ChEBI
585948
Pharos - Ligands
ZNJM1AZL7TDK
PharmacoDB
PDBC00619
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