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Go!
isradipine [extracellular region]
Stable Identifier
R-ALL-9614112
Type
ChemicalDrug
Compartment
extracellular region
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Muscle contraction (Bos taurus)
Cardiac conduction (Bos taurus)
Phase 0 - rapid depolarisation (Bos taurus)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Bos taurus)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Bos taurus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Phase 2 - plateau phase (Bos taurus)
Class IV antihypertensives bind LTCC multimer (Bos taurus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Bos taurus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
LTCC multimer transports Ca2+ from extracellular region to cytosol (Bos taurus)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Bos taurus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Muscle contraction (Caenorhabditis elegans)
Cardiac conduction (Caenorhabditis elegans)
Phase 0 - rapid depolarisation (Caenorhabditis elegans)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Caenorhabditis elegans)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Caenorhabditis elegans)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Phase 2 - plateau phase (Caenorhabditis elegans)
Class IV antihypertensives bind LTCC multimer (Caenorhabditis elegans)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Caenorhabditis elegans)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
LTCC multimer transports Ca2+ from extracellular region to cytosol (Caenorhabditis elegans)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Caenorhabditis elegans)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Muscle contraction (Canis familiaris)
Cardiac conduction (Canis familiaris)
Phase 0 - rapid depolarisation (Canis familiaris)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Canis familiaris)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Canis familiaris)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Phase 2 - plateau phase (Canis familiaris)
Class IV antihypertensives bind LTCC multimer (Canis familiaris)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Canis familiaris)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
LTCC multimer transports Ca2+ from extracellular region to cytosol (Canis familiaris)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Canis familiaris)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Muscle contraction (Drosophila melanogaster)
Cardiac conduction (Drosophila melanogaster)
Phase 0 - rapid depolarisation (Drosophila melanogaster)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Drosophila melanogaster)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Drosophila melanogaster)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Phase 2 - plateau phase (Drosophila melanogaster)
Class IV antihypertensives bind LTCC multimer (Drosophila melanogaster)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Drosophila melanogaster)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
LTCC multimer transports Ca2+ from extracellular region to cytosol (Drosophila melanogaster)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Drosophila melanogaster)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Muscle contraction (Gallus gallus)
Cardiac conduction (Gallus gallus)
Phase 0 - rapid depolarisation (Gallus gallus)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Gallus gallus)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Gallus gallus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Phase 2 - plateau phase (Gallus gallus)
Class IV antihypertensives bind LTCC multimer (Gallus gallus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Gallus gallus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
LTCC multimer transports Ca2+ from extracellular region to cytosol (Gallus gallus)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Gallus gallus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Phase 0 - rapid depolarisation (Homo sapiens)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Homo sapiens)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Homo sapiens)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Phase 2 - plateau phase (Homo sapiens)
Class IV antihypertensives bind LTCC multimer (Homo sapiens)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Homo sapiens)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
LTCC multimer transports Ca2+ from extracellular region to cytosol (Homo sapiens)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Homo sapiens)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Muscle contraction (Mus musculus)
Cardiac conduction (Mus musculus)
Phase 0 - rapid depolarisation (Mus musculus)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Mus musculus)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Mus musculus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Phase 2 - plateau phase (Mus musculus)
Class IV antihypertensives bind LTCC multimer (Mus musculus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Mus musculus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
LTCC multimer transports Ca2+ from extracellular region to cytosol (Mus musculus)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Mus musculus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Muscle contraction (Rattus norvegicus)
Cardiac conduction (Rattus norvegicus)
Phase 0 - rapid depolarisation (Rattus norvegicus)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Rattus norvegicus)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Rattus norvegicus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Phase 2 - plateau phase (Rattus norvegicus)
Class IV antihypertensives bind LTCC multimer (Rattus norvegicus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Rattus norvegicus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
LTCC multimer transports Ca2+ from extracellular region to cytosol (Rattus norvegicus)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Rattus norvegicus)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Muscle contraction (Sus scrofa)
Cardiac conduction (Sus scrofa)
Phase 0 - rapid depolarisation (Sus scrofa)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Sus scrofa)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Sus scrofa)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Phase 2 - plateau phase (Sus scrofa)
Class IV antihypertensives bind LTCC multimer (Sus scrofa)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Sus scrofa)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
LTCC multimer transports Ca2+ from extracellular region to cytosol (Sus scrofa)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Sus scrofa)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Muscle contraction (Xenopus tropicalis)
Cardiac conduction (Xenopus tropicalis)
Phase 0 - rapid depolarisation (Xenopus tropicalis)
LTCC multimer transports Ca2+ from extracellular region to cytosol (Xenopus tropicalis)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Xenopus tropicalis)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Phase 2 - plateau phase (Xenopus tropicalis)
Class IV antihypertensives bind LTCC multimer (Xenopus tropicalis)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Class IV antihypertensives:LTCC multimer [plasma membrane] (Xenopus tropicalis)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
LTCC multimer transports Ca2+ from extracellular region to cytosol (Xenopus tropicalis)
Class IV antihypertensives:LTCC multimer [plasma membrane] (Xenopus tropicalis)
Class IV antihypertensives [extracellular region]
isradipine [extracellular region]
Literature References
PubMed ID
Title
Journal
Year
9916609
Amlodipine, felodipine, and isradipine in the treatment of Chinese patients with mild-to-moderate hypertension
Cheung, BM
,
Lau, CP
,
Wu, BZ
Clin Ther
1998
8458178
Felodipine and isradipine: new calcium-channel-blocking agents for the treatment of hypertension
Walton, T
,
Symes, LR
Clin Pharm
1993
External Reference Information
External Reference
isradipine [Guide to Pharmacology:4488]
Participates
as a member of
Class IV antihypertensives [extracellular region]
Disease
Name
Identifier
Synonyms
hypertension
DOID:10763
High blood pressure (& [essential hypertension]), HTN, hypertensive disease, hyperpiesia, vascular hypertensive disorder
Cross References
Mondo
0005044
ChEBI
6073
,
6073
Pharos - Ligands
ZC55D4516PJZ
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