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bivalirudin [extracellular region]
Stable Identifier
R-ALL-9603269
Type
ProteinDrug
Compartment
extracellular region
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Hemostasis (Bos taurus)
Formation of Fibrin Clot (Clotting Cascade) (Bos taurus)
Common Pathway of Fibrin Clot Formation (Bos taurus)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Bos taurus)
Factor IIa inhibitors:IIa [extracellular region] (Bos taurus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Bos taurus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Intrinsic Pathway of Fibrin Clot Formation (Bos taurus)
Factor IIa inhibitors (peptide) binds IIa (Bos taurus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Factor IIa inhibitors (peptide):IIa [extracellular region] (Bos taurus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Bos taurus)
Factor IIa inhibitors:IIa [extracellular region] (Bos taurus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Bos taurus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Bos taurus)
Factor IIa inhibitors:IIa [extracellular region] (Bos taurus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Bos taurus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Hemostasis (Canis familiaris)
Formation of Fibrin Clot (Clotting Cascade) (Canis familiaris)
Common Pathway of Fibrin Clot Formation (Canis familiaris)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Canis familiaris)
Factor IIa inhibitors:IIa [extracellular region] (Canis familiaris)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Canis familiaris)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Intrinsic Pathway of Fibrin Clot Formation (Canis familiaris)
Factor IIa inhibitors (peptide) binds IIa (Canis familiaris)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Factor IIa inhibitors (peptide):IIa [extracellular region] (Canis familiaris)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Hemostasis (Gallus gallus)
Formation of Fibrin Clot (Clotting Cascade) (Gallus gallus)
Common Pathway of Fibrin Clot Formation (Gallus gallus)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Gallus gallus)
Factor IIa inhibitors:IIa [extracellular region] (Gallus gallus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Gallus gallus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B (Gallus gallus)
Factor IIa inhibitors:IIa [extracellular region] (Gallus gallus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Gallus gallus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Intrinsic Pathway of Fibrin Clot Formation (Gallus gallus)
Factor IIa inhibitors (peptide) binds IIa (Gallus gallus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Factor IIa inhibitors (peptide):IIa [extracellular region] (Gallus gallus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Gallus gallus)
Factor IIa inhibitors:IIa [extracellular region] (Gallus gallus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Gallus gallus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Gallus gallus)
Factor IIa inhibitors:IIa [extracellular region] (Gallus gallus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Gallus gallus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Hemostasis (Homo sapiens)
Formation of Fibrin Clot (Clotting Cascade) (Homo sapiens)
Common Pathway of Fibrin Clot Formation (Homo sapiens)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Homo sapiens)
Factor IIa inhibitors:IIa [extracellular region] (Homo sapiens)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Homo sapiens)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B (Homo sapiens)
Factor IIa inhibitors:IIa [extracellular region] (Homo sapiens)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Homo sapiens)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Intrinsic Pathway of Fibrin Clot Formation (Homo sapiens)
Factor IIa inhibitors (peptide) binds IIa (Homo sapiens)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Factor IIa inhibitors (peptide):IIa [extracellular region] (Homo sapiens)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Homo sapiens)
Factor IIa inhibitors:IIa [extracellular region] (Homo sapiens)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Homo sapiens)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Homo sapiens)
Factor IIa inhibitors:IIa [extracellular region] (Homo sapiens)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Homo sapiens)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Hemostasis (Mus musculus)
Formation of Fibrin Clot (Clotting Cascade) (Mus musculus)
Common Pathway of Fibrin Clot Formation (Mus musculus)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Mus musculus)
Factor IIa inhibitors:IIa [extracellular region] (Mus musculus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Mus musculus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B (Mus musculus)
Factor IIa inhibitors:IIa [extracellular region] (Mus musculus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Mus musculus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Intrinsic Pathway of Fibrin Clot Formation (Mus musculus)
Factor IIa inhibitors (peptide) binds IIa (Mus musculus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Factor IIa inhibitors (peptide):IIa [extracellular region] (Mus musculus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Mus musculus)
Factor IIa inhibitors:IIa [extracellular region] (Mus musculus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Mus musculus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Mus musculus)
Factor IIa inhibitors:IIa [extracellular region] (Mus musculus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Mus musculus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Hemostasis (Rattus norvegicus)
Formation of Fibrin Clot (Clotting Cascade) (Rattus norvegicus)
Common Pathway of Fibrin Clot Formation (Rattus norvegicus)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Rattus norvegicus)
Factor IIa inhibitors:IIa [extracellular region] (Rattus norvegicus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Rattus norvegicus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B (Rattus norvegicus)
Factor IIa inhibitors:IIa [extracellular region] (Rattus norvegicus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Rattus norvegicus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Intrinsic Pathway of Fibrin Clot Formation (Rattus norvegicus)
Factor IIa inhibitors (peptide) binds IIa (Rattus norvegicus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Factor IIa inhibitors (peptide):IIa [extracellular region] (Rattus norvegicus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Rattus norvegicus)
Factor IIa inhibitors:IIa [extracellular region] (Rattus norvegicus)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Rattus norvegicus)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Hemostasis (Sus scrofa)
Formation of Fibrin Clot (Clotting Cascade) (Sus scrofa)
Common Pathway of Fibrin Clot Formation (Sus scrofa)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Sus scrofa)
Factor IIa inhibitors:IIa [extracellular region] (Sus scrofa)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Sus scrofa)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B (Sus scrofa)
Factor IIa inhibitors:IIa [extracellular region] (Sus scrofa)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Sus scrofa)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Intrinsic Pathway of Fibrin Clot Formation (Sus scrofa)
Factor IIa inhibitors (peptide) binds IIa (Sus scrofa)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Factor IIa inhibitors (peptide):IIa [extracellular region] (Sus scrofa)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Sus scrofa)
Factor IIa inhibitors:IIa [extracellular region] (Sus scrofa)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Sus scrofa)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Hemostasis (Xenopus tropicalis)
Formation of Fibrin Clot (Clotting Cascade) (Xenopus tropicalis)
Common Pathway of Fibrin Clot Formation (Xenopus tropicalis)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Xenopus tropicalis)
Factor IIa inhibitors:IIa [extracellular region] (Xenopus tropicalis)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Xenopus tropicalis)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Intrinsic Pathway of Fibrin Clot Formation (Xenopus tropicalis)
Factor IIa inhibitors (peptide) binds IIa (Xenopus tropicalis)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Factor IIa inhibitors (peptide):IIa [extracellular region] (Xenopus tropicalis)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Xenopus tropicalis)
Factor IIa inhibitors:IIa [extracellular region] (Xenopus tropicalis)
Factor IIa inhibitors (peptide):IIa [extracellular region] (Xenopus tropicalis)
Factor IIa inhibitors (peptide) [extracellular region]
bivalirudin [extracellular region]
Literature References
PubMed ID
Title
Journal
Year
11833835
Bivalirudin: a direct thrombin inhibitor
Gladwell, TD
Clin Ther
2002
External Reference Information
External Reference
bivalirudin [Guide to Pharmacology:6470]
Participates
as a member of
Factor IIa inhibitors (peptide) [extracellular region]
Disease
Name
Identifier
Synonyms
pulmonary embolism
DOID:9477
pulmonary embolus, pulmonary artery embolism
Cross References
ChEBI
59173
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