BEZ235

Stable Identifier
R-ALL-2399744
Type
ChemicalDrug
Compartment
Synonyms
NVP-BEZ235, dactolisib
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
18829560 NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations

Serra, V, Markman, B, Scaltriti, M, Eichhorn, PJ, Valero, V, Guzman, M, Botero, ML, Llonch, E, Atzori, F, Di Cosimo, S, Maira, M, Garcia-Echeverria, C, Parra, JL, Arribas, J, Baselga, J

Cancer Res. 2008
18606717 Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

Maira, SM, Stauffer, F, Brueggen, J, Furet, P, Schnell, C, Fritsch, C, Brachmann, S, Chène, P, De Pover, A, Schoemaker, K, Fabbro, D, Gabriel, D, Simonen, M, Murphy, L, Finan, P, Sellers, W, García-Echeverría, C

Mol. Cancer Ther. 2008
Participant Of
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
Cross References
ChEBI