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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
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How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
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TDP [mitochondrial matrix]
Stable Identifier
R-ALL-113547
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
Thiamin diphosphate, thiamine(1+) diphosphate chloride, Thiamine diphosphate, Thiamin pyrophosphate, TPP, ThPP
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Branched-chain amino acid catabolism (Bos taurus)
BCKDH transfers CoA group from CoA-SH to BCAAs (Bos taurus)
lipo-BCKDH [mitochondrial matrix] (Bos taurus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
BCKDK phosphorylates BCKDH (Bos taurus)
lipo-BCKDH [mitochondrial matrix] (Bos taurus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Bos taurus)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
PPM1K dephosphorylates p-BCKDH (Bos taurus)
lipo-BCKDH [mitochondrial matrix] (Bos taurus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Bos taurus)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Bos taurus)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Bos taurus)
DHs [mitochondrial matrix] (Bos taurus)
BCKDH [mitochondrial matrix] (Bos taurus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
PDH [mitochondrial matrix] (Bos taurus)
PDH E1 [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
aKGDH [mitochondrial matrix] (Bos taurus)
aKGDH E1 dimer [mitochondrial matrix] (Bos taurus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
lipoylated DHs [mitochondrial matrix] (Bos taurus)
lipo-BCKDH [mitochondrial matrix] (Bos taurus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
lipo-PDH [mitochondrial matrix] (Bos taurus)
PDH E1 [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
lipo-aKGDH [mitochondrial matrix] (Bos taurus)
aKGDH E1 dimer [mitochondrial matrix] (Bos taurus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
Lysine catabolism (Bos taurus)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Bos taurus)
lipo-aKGDH [mitochondrial matrix] (Bos taurus)
aKGDH E1 dimer [mitochondrial matrix] (Bos taurus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Bos taurus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Bos taurus)
Citric acid cycle (TCA cycle) (Bos taurus)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Bos taurus)
lipo-aKGDH [mitochondrial matrix] (Bos taurus)
aKGDH E1 dimer [mitochondrial matrix] (Bos taurus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
Pyruvate metabolism (Bos taurus)
Regulation of pyruvate dehydrogenase (PDH) complex (Bos taurus)
PDK isoforms phosphorylate lipo-PDH (Bos taurus)
lipo-PDH [mitochondrial matrix] (Bos taurus)
PDH E1 [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Bos taurus)
PDH E1 [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
PDP dephosphorylates p-lipo-PDH (Bos taurus)
lipo-PDH [mitochondrial matrix] (Bos taurus)
PDH E1 [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Bos taurus)
PDH E1 [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Bos taurus)
lipo-PDH [mitochondrial matrix] (Bos taurus)
PDH E1 [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
Signal Transduction (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
Signaling by Retinoic Acid (Bos taurus)
PDK isoforms phosphorylate lipo-PDH (Bos taurus)
lipo-PDH [mitochondrial matrix] (Bos taurus)
PDH E1 [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Bos taurus)
PDH E1 [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Bos taurus)
TDP [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Branched-chain amino acid catabolism (Caenorhabditis elegans)
BCKDH transfers CoA group from CoA-SH to BCAAs (Caenorhabditis elegans)
lipo-BCKDH [mitochondrial matrix] (Caenorhabditis elegans)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Caenorhabditis elegans)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Caenorhabditis elegans)
DHs [mitochondrial matrix] (Caenorhabditis elegans)
BCKDH [mitochondrial matrix] (Caenorhabditis elegans)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
PDH [mitochondrial matrix] (Caenorhabditis elegans)
PDH E1 [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
aKGDH [mitochondrial matrix] (Caenorhabditis elegans)
aKGDH E1 dimer [mitochondrial matrix] (Caenorhabditis elegans)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
lipoylated DHs [mitochondrial matrix] (Caenorhabditis elegans)
lipo-BCKDH [mitochondrial matrix] (Caenorhabditis elegans)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
lipo-PDH [mitochondrial matrix] (Caenorhabditis elegans)
PDH E1 [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
lipo-aKGDH [mitochondrial matrix] (Caenorhabditis elegans)
aKGDH E1 dimer [mitochondrial matrix] (Caenorhabditis elegans)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
Lysine catabolism (Caenorhabditis elegans)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Caenorhabditis elegans)
lipo-aKGDH [mitochondrial matrix] (Caenorhabditis elegans)
aKGDH E1 dimer [mitochondrial matrix] (Caenorhabditis elegans)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Caenorhabditis elegans)
Pyruvate metabolism and Citric Acid (TCA) cycle (Caenorhabditis elegans)
Citric acid cycle (TCA cycle) (Caenorhabditis elegans)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Caenorhabditis elegans)
lipo-aKGDH [mitochondrial matrix] (Caenorhabditis elegans)
aKGDH E1 dimer [mitochondrial matrix] (Caenorhabditis elegans)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
Pyruvate metabolism (Caenorhabditis elegans)
Regulation of pyruvate dehydrogenase (PDH) complex (Caenorhabditis elegans)
PDK isoforms phosphorylate lipo-PDH (Caenorhabditis elegans)
lipo-PDH [mitochondrial matrix] (Caenorhabditis elegans)
PDH E1 [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Caenorhabditis elegans)
PDH E1 [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
PDP dephosphorylates p-lipo-PDH (Caenorhabditis elegans)
lipo-PDH [mitochondrial matrix] (Caenorhabditis elegans)
PDH E1 [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Caenorhabditis elegans)
PDH E1 [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Caenorhabditis elegans)
lipo-PDH [mitochondrial matrix] (Caenorhabditis elegans)
PDH E1 [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
Signal Transduction (Caenorhabditis elegans)
Signaling by Nuclear Receptors (Caenorhabditis elegans)
Signaling by Retinoic Acid (Caenorhabditis elegans)
PDK isoforms phosphorylate lipo-PDH (Caenorhabditis elegans)
lipo-PDH [mitochondrial matrix] (Caenorhabditis elegans)
PDH E1 [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Caenorhabditis elegans)
PDH E1 [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Caenorhabditis elegans)
TDP [mitochondrial matrix]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Branched-chain amino acid catabolism (Canis familiaris)
BCKDH transfers CoA group from CoA-SH to BCAAs (Canis familiaris)
lipo-BCKDH [mitochondrial matrix] (Canis familiaris)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
BCKDK phosphorylates BCKDH (Canis familiaris)
lipo-BCKDH [mitochondrial matrix] (Canis familiaris)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Canis familiaris)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
PPM1K dephosphorylates p-BCKDH (Canis familiaris)
lipo-BCKDH [mitochondrial matrix] (Canis familiaris)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Canis familiaris)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Canis familiaris)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Canis familiaris)
DHs [mitochondrial matrix] (Canis familiaris)
BCKDH [mitochondrial matrix] (Canis familiaris)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
PDH [mitochondrial matrix] (Canis familiaris)
PDH E1 [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
aKGDH [mitochondrial matrix] (Canis familiaris)
aKGDH E1 dimer [mitochondrial matrix] (Canis familiaris)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
lipoylated DHs [mitochondrial matrix] (Canis familiaris)
lipo-BCKDH [mitochondrial matrix] (Canis familiaris)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
lipo-PDH [mitochondrial matrix] (Canis familiaris)
PDH E1 [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
lipo-aKGDH [mitochondrial matrix] (Canis familiaris)
aKGDH E1 dimer [mitochondrial matrix] (Canis familiaris)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
Lysine catabolism (Canis familiaris)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Canis familiaris)
lipo-aKGDH [mitochondrial matrix] (Canis familiaris)
aKGDH E1 dimer [mitochondrial matrix] (Canis familiaris)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Canis familiaris)
Pyruvate metabolism and Citric Acid (TCA) cycle (Canis familiaris)
Citric acid cycle (TCA cycle) (Canis familiaris)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Canis familiaris)
lipo-aKGDH [mitochondrial matrix] (Canis familiaris)
aKGDH E1 dimer [mitochondrial matrix] (Canis familiaris)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
Pyruvate metabolism (Canis familiaris)
Regulation of pyruvate dehydrogenase (PDH) complex (Canis familiaris)
PDK isoforms phosphorylate lipo-PDH (Canis familiaris)
lipo-PDH [mitochondrial matrix] (Canis familiaris)
PDH E1 [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Canis familiaris)
PDH E1 [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
PDP dephosphorylates p-lipo-PDH (Canis familiaris)
lipo-PDH [mitochondrial matrix] (Canis familiaris)
PDH E1 [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Canis familiaris)
PDH E1 [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Canis familiaris)
lipo-PDH [mitochondrial matrix] (Canis familiaris)
PDH E1 [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
Signaling by Retinoic Acid (Canis familiaris)
PDK isoforms phosphorylate lipo-PDH (Canis familiaris)
lipo-PDH [mitochondrial matrix] (Canis familiaris)
PDH E1 [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Canis familiaris)
PDH E1 [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Canis familiaris)
TDP [mitochondrial matrix]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Branched-chain amino acid catabolism (Danio rerio)
BCKDH transfers CoA group from CoA-SH to BCAAs (Danio rerio)
lipo-BCKDH [mitochondrial matrix] (Danio rerio)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
BCKDK phosphorylates BCKDH (Danio rerio)
lipo-BCKDH [mitochondrial matrix] (Danio rerio)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Danio rerio)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
PPM1K dephosphorylates p-BCKDH (Danio rerio)
lipo-BCKDH [mitochondrial matrix] (Danio rerio)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Danio rerio)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Danio rerio)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Danio rerio)
DHs [mitochondrial matrix] (Danio rerio)
BCKDH [mitochondrial matrix] (Danio rerio)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
PDH [mitochondrial matrix] (Danio rerio)
PDH E1 [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
aKGDH [mitochondrial matrix] (Danio rerio)
aKGDH E1 dimer [mitochondrial matrix] (Danio rerio)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
lipoylated DHs [mitochondrial matrix] (Danio rerio)
lipo-BCKDH [mitochondrial matrix] (Danio rerio)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
lipo-PDH [mitochondrial matrix] (Danio rerio)
PDH E1 [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
lipo-aKGDH [mitochondrial matrix] (Danio rerio)
aKGDH E1 dimer [mitochondrial matrix] (Danio rerio)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
Lysine catabolism (Danio rerio)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Danio rerio)
lipo-aKGDH [mitochondrial matrix] (Danio rerio)
aKGDH E1 dimer [mitochondrial matrix] (Danio rerio)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Danio rerio)
Pyruvate metabolism and Citric Acid (TCA) cycle (Danio rerio)
Citric acid cycle (TCA cycle) (Danio rerio)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Danio rerio)
lipo-aKGDH [mitochondrial matrix] (Danio rerio)
aKGDH E1 dimer [mitochondrial matrix] (Danio rerio)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
Pyruvate metabolism (Danio rerio)
Regulation of pyruvate dehydrogenase (PDH) complex (Danio rerio)
PDK isoforms phosphorylate lipo-PDH (Danio rerio)
lipo-PDH [mitochondrial matrix] (Danio rerio)
PDH E1 [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Danio rerio)
PDH E1 [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
PDP dephosphorylates p-lipo-PDH (Danio rerio)
lipo-PDH [mitochondrial matrix] (Danio rerio)
PDH E1 [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Danio rerio)
PDH E1 [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Danio rerio)
lipo-PDH [mitochondrial matrix] (Danio rerio)
PDH E1 [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
Signal Transduction (Danio rerio)
Signaling by Nuclear Receptors (Danio rerio)
Signaling by Retinoic Acid (Danio rerio)
PDK isoforms phosphorylate lipo-PDH (Danio rerio)
lipo-PDH [mitochondrial matrix] (Danio rerio)
PDH E1 [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Danio rerio)
PDH E1 [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Danio rerio)
TDP [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Branched-chain amino acid catabolism (Dictyostelium discoideum)
BCKDH transfers CoA group from CoA-SH to BCAAs (Dictyostelium discoideum)
lipo-BCKDH [mitochondrial matrix] (Dictyostelium discoideum)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Dictyostelium discoideum)
TDP [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Dictyostelium discoideum)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Dictyostelium discoideum)
DHs [mitochondrial matrix] (Dictyostelium discoideum)
BCKDH [mitochondrial matrix] (Dictyostelium discoideum)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Dictyostelium discoideum)
TDP [mitochondrial matrix]
PDH [mitochondrial matrix] (Dictyostelium discoideum)
PDH E1 [mitochondrial matrix] (Dictyostelium discoideum)
TDP [mitochondrial matrix]
aKGDH [mitochondrial matrix] (Dictyostelium discoideum)
aKGDH E1 dimer [mitochondrial matrix] (Dictyostelium discoideum)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Dictyostelium discoideum)
TDP [mitochondrial matrix]
lipoylated DHs [mitochondrial matrix] (Dictyostelium discoideum)
lipo-BCKDH [mitochondrial matrix] (Dictyostelium discoideum)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Dictyostelium discoideum)
TDP [mitochondrial matrix]
lipo-PDH [mitochondrial matrix] (Dictyostelium discoideum)
PDH E1 [mitochondrial matrix] (Dictyostelium discoideum)
TDP [mitochondrial matrix]
lipo-aKGDH [mitochondrial matrix] (Dictyostelium discoideum)
aKGDH E1 dimer [mitochondrial matrix] (Dictyostelium discoideum)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Dictyostelium discoideum)
TDP [mitochondrial matrix]
Lysine catabolism (Dictyostelium discoideum)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Dictyostelium discoideum)
lipo-aKGDH [mitochondrial matrix] (Dictyostelium discoideum)
aKGDH E1 dimer [mitochondrial matrix] (Dictyostelium discoideum)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Dictyostelium discoideum)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Dictyostelium discoideum)
Pyruvate metabolism and Citric Acid (TCA) cycle (Dictyostelium discoideum)
Citric acid cycle (TCA cycle) (Dictyostelium discoideum)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Dictyostelium discoideum)
lipo-aKGDH [mitochondrial matrix] (Dictyostelium discoideum)
aKGDH E1 dimer [mitochondrial matrix] (Dictyostelium discoideum)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Dictyostelium discoideum)
TDP [mitochondrial matrix]
Pyruvate metabolism (Dictyostelium discoideum)
lipo-PDH decarboxylates PYR to Ac-CoA (Dictyostelium discoideum)
lipo-PDH [mitochondrial matrix] (Dictyostelium discoideum)
PDH E1 [mitochondrial matrix] (Dictyostelium discoideum)
TDP [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Branched-chain amino acid catabolism (Drosophila melanogaster)
BCKDH transfers CoA group from CoA-SH to BCAAs (Drosophila melanogaster)
lipo-BCKDH [mitochondrial matrix] (Drosophila melanogaster)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Drosophila melanogaster)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Drosophila melanogaster)
DHs [mitochondrial matrix] (Drosophila melanogaster)
BCKDH [mitochondrial matrix] (Drosophila melanogaster)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
PDH [mitochondrial matrix] (Drosophila melanogaster)
PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
aKGDH [mitochondrial matrix] (Drosophila melanogaster)
aKGDH E1 dimer [mitochondrial matrix] (Drosophila melanogaster)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
lipoylated DHs [mitochondrial matrix] (Drosophila melanogaster)
lipo-BCKDH [mitochondrial matrix] (Drosophila melanogaster)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
lipo-PDH [mitochondrial matrix] (Drosophila melanogaster)
PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
lipo-aKGDH [mitochondrial matrix] (Drosophila melanogaster)
aKGDH E1 dimer [mitochondrial matrix] (Drosophila melanogaster)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
Lysine catabolism (Drosophila melanogaster)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Drosophila melanogaster)
lipo-aKGDH [mitochondrial matrix] (Drosophila melanogaster)
aKGDH E1 dimer [mitochondrial matrix] (Drosophila melanogaster)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism and Citric Acid (TCA) cycle (Drosophila melanogaster)
Citric acid cycle (TCA cycle) (Drosophila melanogaster)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Drosophila melanogaster)
lipo-aKGDH [mitochondrial matrix] (Drosophila melanogaster)
aKGDH E1 dimer [mitochondrial matrix] (Drosophila melanogaster)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
Pyruvate metabolism (Drosophila melanogaster)
Regulation of pyruvate dehydrogenase (PDH) complex (Drosophila melanogaster)
PDK isoforms phosphorylate lipo-PDH (Drosophila melanogaster)
lipo-PDH [mitochondrial matrix] (Drosophila melanogaster)
PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Drosophila melanogaster)
PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
PDP dephosphorylates p-lipo-PDH (Drosophila melanogaster)
lipo-PDH [mitochondrial matrix] (Drosophila melanogaster)
PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Drosophila melanogaster)
PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Drosophila melanogaster)
lipo-PDH [mitochondrial matrix] (Drosophila melanogaster)
PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
Signaling by Retinoic Acid (Drosophila melanogaster)
PDK isoforms phosphorylate lipo-PDH (Drosophila melanogaster)
lipo-PDH [mitochondrial matrix] (Drosophila melanogaster)
PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Drosophila melanogaster)
PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
TDP [mitochondrial matrix]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Branched-chain amino acid catabolism (Gallus gallus)
BCKDH transfers CoA group from CoA-SH to BCAAs (Gallus gallus)
lipo-BCKDH [mitochondrial matrix] (Gallus gallus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
PPM1K dephosphorylates p-BCKDH (Gallus gallus)
lipo-BCKDH [mitochondrial matrix] (Gallus gallus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Gallus gallus)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Gallus gallus)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Gallus gallus)
DHs [mitochondrial matrix] (Gallus gallus)
BCKDH [mitochondrial matrix] (Gallus gallus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
PDH [mitochondrial matrix] (Gallus gallus)
PDH E1 [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
aKGDH [mitochondrial matrix] (Gallus gallus)
aKGDH E1 dimer [mitochondrial matrix] (Gallus gallus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
lipoylated DHs [mitochondrial matrix] (Gallus gallus)
lipo-BCKDH [mitochondrial matrix] (Gallus gallus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
lipo-PDH [mitochondrial matrix] (Gallus gallus)
PDH E1 [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
lipo-aKGDH [mitochondrial matrix] (Gallus gallus)
aKGDH E1 dimer [mitochondrial matrix] (Gallus gallus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
Lysine catabolism (Gallus gallus)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Gallus gallus)
lipo-aKGDH [mitochondrial matrix] (Gallus gallus)
aKGDH E1 dimer [mitochondrial matrix] (Gallus gallus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Gallus gallus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Gallus gallus)
Citric acid cycle (TCA cycle) (Gallus gallus)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Gallus gallus)
lipo-aKGDH [mitochondrial matrix] (Gallus gallus)
aKGDH E1 dimer [mitochondrial matrix] (Gallus gallus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
Pyruvate metabolism (Gallus gallus)
Regulation of pyruvate dehydrogenase (PDH) complex (Gallus gallus)
PDK isoforms phosphorylate lipo-PDH (Gallus gallus)
lipo-PDH [mitochondrial matrix] (Gallus gallus)
PDH E1 [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Gallus gallus)
PDH E1 [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
PDP dephosphorylates p-lipo-PDH (Gallus gallus)
lipo-PDH [mitochondrial matrix] (Gallus gallus)
PDH E1 [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Gallus gallus)
PDH E1 [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Gallus gallus)
lipo-PDH [mitochondrial matrix] (Gallus gallus)
PDH E1 [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
Signal Transduction (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
Signaling by Retinoic Acid (Gallus gallus)
PDK isoforms phosphorylate lipo-PDH (Gallus gallus)
lipo-PDH [mitochondrial matrix] (Gallus gallus)
PDH E1 [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Gallus gallus)
PDH E1 [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Gallus gallus)
TDP [mitochondrial matrix]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Branched-chain amino acid catabolism (Homo sapiens)
BCKDH transfers CoA group from CoA-SH to BCAAs (Homo sapiens)
lipo-BCKDH [mitochondrial matrix] (Homo sapiens)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
BCKDK phosphorylates BCKDH (Homo sapiens)
lipo-BCKDH [mitochondrial matrix] (Homo sapiens)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Homo sapiens)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
PPM1K dephosphorylates p-BCKDH (Homo sapiens)
lipo-BCKDH [mitochondrial matrix] (Homo sapiens)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Homo sapiens)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Homo sapiens)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Homo sapiens)
DHs [mitochondrial matrix] (Homo sapiens)
BCKDH [mitochondrial matrix] (Homo sapiens)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
PDH [mitochondrial matrix] (Homo sapiens)
PDH E1 [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
aKGDH [mitochondrial matrix] (Homo sapiens)
aKGDH E1 dimer [mitochondrial matrix] (Homo sapiens)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
lipoylated DHs [mitochondrial matrix] (Homo sapiens)
lipo-BCKDH [mitochondrial matrix] (Homo sapiens)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
lipo-PDH [mitochondrial matrix] (Homo sapiens)
PDH E1 [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
lipo-aKGDH [mitochondrial matrix] (Homo sapiens)
aKGDH E1 dimer [mitochondrial matrix] (Homo sapiens)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
Lysine catabolism (Homo sapiens)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Homo sapiens)
lipo-aKGDH [mitochondrial matrix] (Homo sapiens)
aKGDH E1 dimer [mitochondrial matrix] (Homo sapiens)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Homo sapiens)
Pyruvate metabolism and Citric Acid (TCA) cycle (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Homo sapiens)
lipo-aKGDH [mitochondrial matrix] (Homo sapiens)
aKGDH E1 dimer [mitochondrial matrix] (Homo sapiens)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
Pyruvate metabolism (Homo sapiens)
Regulation of pyruvate dehydrogenase (PDH) complex (Homo sapiens)
PDK isoforms phosphorylate lipo-PDH (Homo sapiens)
lipo-PDH [mitochondrial matrix] (Homo sapiens)
PDH E1 [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Homo sapiens)
PDH E1 [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
PDP dephosphorylates p-lipo-PDH (Homo sapiens)
lipo-PDH [mitochondrial matrix] (Homo sapiens)
PDH E1 [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Homo sapiens)
PDH E1 [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Homo sapiens)
lipo-PDH [mitochondrial matrix] (Homo sapiens)
PDH E1 [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
Signaling by Retinoic Acid (Homo sapiens)
PDK isoforms phosphorylate lipo-PDH (Homo sapiens)
lipo-PDH [mitochondrial matrix] (Homo sapiens)
PDH E1 [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Homo sapiens)
PDH E1 [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Homo sapiens)
TDP [mitochondrial matrix]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Branched-chain amino acid catabolism (Mus musculus)
BCKDH transfers CoA group from CoA-SH to BCAAs (Mus musculus)
lipo-BCKDH [mitochondrial matrix] (Mus musculus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
BCKDK phosphorylates BCKDH (Mus musculus)
lipo-BCKDH [mitochondrial matrix] (Mus musculus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Mus musculus)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
PPM1K dephosphorylates p-BCKDH (Mus musculus)
lipo-BCKDH [mitochondrial matrix] (Mus musculus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Mus musculus)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Mus musculus)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Mus musculus)
DHs [mitochondrial matrix] (Mus musculus)
BCKDH [mitochondrial matrix] (Mus musculus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
PDH [mitochondrial matrix] (Mus musculus)
PDH E1 [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
aKGDH [mitochondrial matrix] (Mus musculus)
aKGDH E1 dimer [mitochondrial matrix] (Mus musculus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
lipoylated DHs [mitochondrial matrix] (Mus musculus)
lipo-BCKDH [mitochondrial matrix] (Mus musculus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
lipo-PDH [mitochondrial matrix] (Mus musculus)
PDH E1 [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
lipo-aKGDH [mitochondrial matrix] (Mus musculus)
aKGDH E1 dimer [mitochondrial matrix] (Mus musculus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
Lysine catabolism (Mus musculus)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Mus musculus)
lipo-aKGDH [mitochondrial matrix] (Mus musculus)
aKGDH E1 dimer [mitochondrial matrix] (Mus musculus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Mus musculus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Mus musculus)
Citric acid cycle (TCA cycle) (Mus musculus)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Mus musculus)
lipo-aKGDH [mitochondrial matrix] (Mus musculus)
aKGDH E1 dimer [mitochondrial matrix] (Mus musculus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
Pyruvate metabolism (Mus musculus)
Regulation of pyruvate dehydrogenase (PDH) complex (Mus musculus)
PDK isoforms phosphorylate lipo-PDH (Mus musculus)
lipo-PDH [mitochondrial matrix] (Mus musculus)
PDH E1 [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Mus musculus)
PDH E1 [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
PDP dephosphorylates p-lipo-PDH (Mus musculus)
lipo-PDH [mitochondrial matrix] (Mus musculus)
PDH E1 [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Mus musculus)
PDH E1 [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Mus musculus)
lipo-PDH [mitochondrial matrix] (Mus musculus)
PDH E1 [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
Signaling by Retinoic Acid (Mus musculus)
PDK isoforms phosphorylate lipo-PDH (Mus musculus)
lipo-PDH [mitochondrial matrix] (Mus musculus)
PDH E1 [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Mus musculus)
PDH E1 [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Mus musculus)
TDP [mitochondrial matrix]
Metabolism (Plasmodium falciparum)
Metabolism of amino acids and derivatives (Plasmodium falciparum)
Branched-chain amino acid catabolism (Plasmodium falciparum)
BCKDH transfers CoA group from CoA-SH to BCAAs (Plasmodium falciparum)
lipo-BCKDH [mitochondrial matrix] (Plasmodium falciparum)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Plasmodium falciparum)
TDP [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Plasmodium falciparum)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Plasmodium falciparum)
DHs [mitochondrial matrix] (Plasmodium falciparum)
BCKDH [mitochondrial matrix] (Plasmodium falciparum)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Plasmodium falciparum)
TDP [mitochondrial matrix]
aKGDH [mitochondrial matrix] (Plasmodium falciparum)
aKGDH E1 dimer [mitochondrial matrix] (Plasmodium falciparum)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Plasmodium falciparum)
TDP [mitochondrial matrix]
lipoylated DHs [mitochondrial matrix] (Plasmodium falciparum)
lipo-BCKDH [mitochondrial matrix] (Plasmodium falciparum)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Plasmodium falciparum)
TDP [mitochondrial matrix]
lipo-aKGDH [mitochondrial matrix] (Plasmodium falciparum)
aKGDH E1 dimer [mitochondrial matrix] (Plasmodium falciparum)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Plasmodium falciparum)
TDP [mitochondrial matrix]
Lysine catabolism (Plasmodium falciparum)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Plasmodium falciparum)
lipo-aKGDH [mitochondrial matrix] (Plasmodium falciparum)
aKGDH E1 dimer [mitochondrial matrix] (Plasmodium falciparum)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Plasmodium falciparum)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Plasmodium falciparum)
Pyruvate metabolism and Citric Acid (TCA) cycle (Plasmodium falciparum)
Citric acid cycle (TCA cycle) (Plasmodium falciparum)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Plasmodium falciparum)
lipo-aKGDH [mitochondrial matrix] (Plasmodium falciparum)
aKGDH E1 dimer [mitochondrial matrix] (Plasmodium falciparum)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Plasmodium falciparum)
TDP [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Branched-chain amino acid catabolism (Rattus norvegicus)
BCKDH transfers CoA group from CoA-SH to BCAAs (Rattus norvegicus)
lipo-BCKDH [mitochondrial matrix] (Rattus norvegicus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
BCKDK phosphorylates BCKDH (Rattus norvegicus)
lipo-BCKDH [mitochondrial matrix] (Rattus norvegicus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Rattus norvegicus)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
PPM1K dephosphorylates p-BCKDH (Rattus norvegicus)
lipo-BCKDH [mitochondrial matrix] (Rattus norvegicus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Rattus norvegicus)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Rattus norvegicus)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Rattus norvegicus)
DHs [mitochondrial matrix] (Rattus norvegicus)
BCKDH [mitochondrial matrix] (Rattus norvegicus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
PDH [mitochondrial matrix] (Rattus norvegicus)
PDH E1 [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
aKGDH [mitochondrial matrix] (Rattus norvegicus)
aKGDH E1 dimer [mitochondrial matrix] (Rattus norvegicus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
lipoylated DHs [mitochondrial matrix] (Rattus norvegicus)
lipo-BCKDH [mitochondrial matrix] (Rattus norvegicus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
lipo-PDH [mitochondrial matrix] (Rattus norvegicus)
PDH E1 [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
lipo-aKGDH [mitochondrial matrix] (Rattus norvegicus)
aKGDH E1 dimer [mitochondrial matrix] (Rattus norvegicus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
Lysine catabolism (Rattus norvegicus)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Rattus norvegicus)
lipo-aKGDH [mitochondrial matrix] (Rattus norvegicus)
aKGDH E1 dimer [mitochondrial matrix] (Rattus norvegicus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Rattus norvegicus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Rattus norvegicus)
Citric acid cycle (TCA cycle) (Rattus norvegicus)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Rattus norvegicus)
lipo-aKGDH [mitochondrial matrix] (Rattus norvegicus)
aKGDH E1 dimer [mitochondrial matrix] (Rattus norvegicus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
Pyruvate metabolism (Rattus norvegicus)
Regulation of pyruvate dehydrogenase (PDH) complex (Rattus norvegicus)
PDK isoforms phosphorylate lipo-PDH (Rattus norvegicus)
lipo-PDH [mitochondrial matrix] (Rattus norvegicus)
PDH E1 [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Rattus norvegicus)
PDH E1 [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
PDP dephosphorylates p-lipo-PDH (Rattus norvegicus)
lipo-PDH [mitochondrial matrix] (Rattus norvegicus)
PDH E1 [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Rattus norvegicus)
PDH E1 [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Rattus norvegicus)
lipo-PDH [mitochondrial matrix] (Rattus norvegicus)
PDH E1 [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
Signaling by Retinoic Acid (Rattus norvegicus)
PDK isoforms phosphorylate lipo-PDH (Rattus norvegicus)
lipo-PDH [mitochondrial matrix] (Rattus norvegicus)
PDH E1 [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Rattus norvegicus)
PDH E1 [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Rattus norvegicus)
TDP [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Glyoxylate metabolism and glycine degradation (Saccharomyces cerevisiae)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Saccharomyces cerevisiae)
DHs [mitochondrial matrix] (Saccharomyces cerevisiae)
PDH [mitochondrial matrix] (Saccharomyces cerevisiae)
PDH E1 [mitochondrial matrix] (Saccharomyces cerevisiae)
TDP [mitochondrial matrix]
aKGDH [mitochondrial matrix] (Saccharomyces cerevisiae)
aKGDH E1 dimer [mitochondrial matrix] (Saccharomyces cerevisiae)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Saccharomyces cerevisiae)
TDP [mitochondrial matrix]
lipoylated DHs [mitochondrial matrix] (Saccharomyces cerevisiae)
lipo-PDH [mitochondrial matrix] (Saccharomyces cerevisiae)
PDH E1 [mitochondrial matrix] (Saccharomyces cerevisiae)
TDP [mitochondrial matrix]
lipo-aKGDH [mitochondrial matrix] (Saccharomyces cerevisiae)
aKGDH E1 dimer [mitochondrial matrix] (Saccharomyces cerevisiae)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Saccharomyces cerevisiae)
TDP [mitochondrial matrix]
Lysine catabolism (Saccharomyces cerevisiae)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Saccharomyces cerevisiae)
lipo-aKGDH [mitochondrial matrix] (Saccharomyces cerevisiae)
aKGDH E1 dimer [mitochondrial matrix] (Saccharomyces cerevisiae)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Saccharomyces cerevisiae)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Saccharomyces cerevisiae)
Pyruvate metabolism and Citric Acid (TCA) cycle (Saccharomyces cerevisiae)
Citric acid cycle (TCA cycle) (Saccharomyces cerevisiae)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Saccharomyces cerevisiae)
lipo-aKGDH [mitochondrial matrix] (Saccharomyces cerevisiae)
aKGDH E1 dimer [mitochondrial matrix] (Saccharomyces cerevisiae)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Saccharomyces cerevisiae)
TDP [mitochondrial matrix]
Pyruvate metabolism (Saccharomyces cerevisiae)
lipo-PDH decarboxylates PYR to Ac-CoA (Saccharomyces cerevisiae)
lipo-PDH [mitochondrial matrix] (Saccharomyces cerevisiae)
PDH E1 [mitochondrial matrix] (Saccharomyces cerevisiae)
TDP [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Glyoxylate metabolism and glycine degradation (Schizosaccharomyces pombe)
LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs (Schizosaccharomyces pombe)
DHs [mitochondrial matrix] (Schizosaccharomyces pombe)
PDH [mitochondrial matrix] (Schizosaccharomyces pombe)
PDH E1 [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
aKGDH [mitochondrial matrix] (Schizosaccharomyces pombe)
aKGDH E1 dimer [mitochondrial matrix] (Schizosaccharomyces pombe)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
lipoylated DHs [mitochondrial matrix] (Schizosaccharomyces pombe)
lipo-PDH [mitochondrial matrix] (Schizosaccharomyces pombe)
PDH E1 [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
lipo-aKGDH [mitochondrial matrix] (Schizosaccharomyces pombe)
aKGDH E1 dimer [mitochondrial matrix] (Schizosaccharomyces pombe)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
Lysine catabolism (Schizosaccharomyces pombe)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Schizosaccharomyces pombe)
lipo-aKGDH [mitochondrial matrix] (Schizosaccharomyces pombe)
aKGDH E1 dimer [mitochondrial matrix] (Schizosaccharomyces pombe)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Schizosaccharomyces pombe)
Pyruvate metabolism and Citric Acid (TCA) cycle (Schizosaccharomyces pombe)
Citric acid cycle (TCA cycle) (Schizosaccharomyces pombe)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Schizosaccharomyces pombe)
lipo-aKGDH [mitochondrial matrix] (Schizosaccharomyces pombe)
aKGDH E1 dimer [mitochondrial matrix] (Schizosaccharomyces pombe)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
Pyruvate metabolism (Schizosaccharomyces pombe)
Regulation of pyruvate dehydrogenase (PDH) complex (Schizosaccharomyces pombe)
PDK isoforms phosphorylate lipo-PDH (Schizosaccharomyces pombe)
lipo-PDH [mitochondrial matrix] (Schizosaccharomyces pombe)
PDH E1 [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Schizosaccharomyces pombe)
PDH E1 [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Schizosaccharomyces pombe)
lipo-PDH [mitochondrial matrix] (Schizosaccharomyces pombe)
PDH E1 [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
Signal Transduction (Schizosaccharomyces pombe)
Signaling by Nuclear Receptors (Schizosaccharomyces pombe)
Signaling by Retinoic Acid (Schizosaccharomyces pombe)
PDK isoforms phosphorylate lipo-PDH (Schizosaccharomyces pombe)
lipo-PDH [mitochondrial matrix] (Schizosaccharomyces pombe)
PDH E1 [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Schizosaccharomyces pombe)
PDH E1 [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Schizosaccharomyces pombe)
TDP [mitochondrial matrix]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Branched-chain amino acid catabolism (Sus scrofa)
BCKDH transfers CoA group from CoA-SH to BCAAs (Sus scrofa)
lipo-BCKDH [mitochondrial matrix] (Sus scrofa)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
BCKDK phosphorylates BCKDH (Sus scrofa)
lipo-BCKDH [mitochondrial matrix] (Sus scrofa)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Sus scrofa)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
PPM1K dephosphorylates p-BCKDH (Sus scrofa)
lipo-BCKDH [mitochondrial matrix] (Sus scrofa)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Sus scrofa)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
Lysine catabolism (Sus scrofa)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Sus scrofa)
lipo-aKGDH [mitochondrial matrix] (Sus scrofa)
aKGDH E1 dimer [mitochondrial matrix] (Sus scrofa)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Sus scrofa)
Pyruvate metabolism and Citric Acid (TCA) cycle (Sus scrofa)
Citric acid cycle (TCA cycle) (Sus scrofa)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Sus scrofa)
lipo-aKGDH [mitochondrial matrix] (Sus scrofa)
aKGDH E1 dimer [mitochondrial matrix] (Sus scrofa)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
Pyruvate metabolism (Sus scrofa)
Regulation of pyruvate dehydrogenase (PDH) complex (Sus scrofa)
PDK isoforms phosphorylate lipo-PDH (Sus scrofa)
lipo-PDH [mitochondrial matrix] (Sus scrofa)
PDH E1 [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Sus scrofa)
PDH E1 [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
PDP dephosphorylates p-lipo-PDH (Sus scrofa)
lipo-PDH [mitochondrial matrix] (Sus scrofa)
PDH E1 [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Sus scrofa)
PDH E1 [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Sus scrofa)
lipo-PDH [mitochondrial matrix] (Sus scrofa)
PDH E1 [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
Signaling by Retinoic Acid (Sus scrofa)
PDK isoforms phosphorylate lipo-PDH (Sus scrofa)
lipo-PDH [mitochondrial matrix] (Sus scrofa)
PDH E1 [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Sus scrofa)
PDH E1 [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Sus scrofa)
TDP [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Branched-chain amino acid catabolism (Xenopus tropicalis)
BCKDH transfers CoA group from CoA-SH to BCAAs (Xenopus tropicalis)
lipo-BCKDH [mitochondrial matrix] (Xenopus tropicalis)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
BCKDK phosphorylates BCKDH (Xenopus tropicalis)
lipo-BCKDH [mitochondrial matrix] (Xenopus tropicalis)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Xenopus tropicalis)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
PPM1K dephosphorylates p-BCKDH (Xenopus tropicalis)
lipo-BCKDH [mitochondrial matrix] (Xenopus tropicalis)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
p-BCKDH [mitochondrial matrix] (Xenopus tropicalis)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
Lysine catabolism (Xenopus tropicalis)
alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ (Xenopus tropicalis)
lipo-aKGDH [mitochondrial matrix] (Xenopus tropicalis)
aKGDH E1 dimer [mitochondrial matrix] (Xenopus tropicalis)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Xenopus tropicalis)
Pyruvate metabolism and Citric Acid (TCA) cycle (Xenopus tropicalis)
Citric acid cycle (TCA cycle) (Xenopus tropicalis)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Xenopus tropicalis)
lipo-aKGDH [mitochondrial matrix] (Xenopus tropicalis)
aKGDH E1 dimer [mitochondrial matrix] (Xenopus tropicalis)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
Pyruvate metabolism (Xenopus tropicalis)
Regulation of pyruvate dehydrogenase (PDH) complex (Xenopus tropicalis)
PDK isoforms phosphorylate lipo-PDH (Xenopus tropicalis)
lipo-PDH [mitochondrial matrix] (Xenopus tropicalis)
PDH E1 [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Xenopus tropicalis)
PDH E1 [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
PDP dephosphorylates p-lipo-PDH (Xenopus tropicalis)
lipo-PDH [mitochondrial matrix] (Xenopus tropicalis)
PDH E1 [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Xenopus tropicalis)
PDH E1 [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Xenopus tropicalis)
lipo-PDH [mitochondrial matrix] (Xenopus tropicalis)
PDH E1 [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
Signal Transduction (Xenopus tropicalis)
Signaling by Nuclear Receptors (Xenopus tropicalis)
Signaling by Retinoic Acid (Xenopus tropicalis)
PDK isoforms phosphorylate lipo-PDH (Xenopus tropicalis)
lipo-PDH [mitochondrial matrix] (Xenopus tropicalis)
PDH E1 [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
p-lipo-PDH [mitochondrial matrix] (Xenopus tropicalis)
PDH E1 [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
PDH E1 [mitochondrial matrix] (Xenopus tropicalis)
TDP [mitochondrial matrix]
External Reference Information
External Reference
thiamine(1+) diphosphate(3-) [ChEBI:58937]
Participates
as a component of
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Mus musculus)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Danio rerio)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Drosophila melanogaster)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Rattus norvegicus)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Caenorhabditis elegans)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Xenopus tropicalis)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Canis familiaris)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Dictyostelium discoideum)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Bos taurus)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Gallus gallus)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Plasmodium falciparum)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Sus scrofa)
phosphorylated branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Homo sapiens)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Sus scrofa)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Caenorhabditis elegans)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Drosophila melanogaster)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Bos taurus)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Dictyostelium discoideum)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Xenopus tropicalis)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Gallus gallus)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Danio rerio)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Saccharomyces cerevisiae)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Schizosaccharomyces pombe)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Canis familiaris)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Homo sapiens)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Xenopus tropicalis)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Drosophila melanogaster)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Rattus norvegicus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Gallus gallus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Bos taurus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Sus scrofa)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Caenorhabditis elegans)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Plasmodium falciparum)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Dictyostelium discoideum)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Mus musculus)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Canis familiaris)
branched-chain alpha-ketoacid dehydrogenase E1 complex [mitochondrial matrix] (Danio rerio)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Homo sapiens)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Canis familiaris)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Bos taurus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Dictyostelium discoideum)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Schizosaccharomyces pombe)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Sus scrofa)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Xenopus tropicalis)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Mus musculus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Danio rerio)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Drosophila melanogaster)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Caenorhabditis elegans)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Rattus norvegicus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Plasmodium falciparum)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Gallus gallus)
alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Saccharomyces cerevisiae)
PDH E1 [mitochondrial matrix] (Homo sapiens)
PDH E1 [mitochondrial matrix] (Caenorhabditis elegans)
PDH E1 [mitochondrial matrix] (Schizosaccharomyces pombe)
PDH E1 [mitochondrial matrix] (Danio rerio)
PDH E1 [mitochondrial matrix] (Rattus norvegicus)
PDH E1 [mitochondrial matrix] (Bos taurus)
PDH E1 [mitochondrial matrix] (Sus scrofa)
PDH E1 [mitochondrial matrix] (Gallus gallus)
PDH E1 [mitochondrial matrix] (Drosophila melanogaster)
PDH E1 [mitochondrial matrix] (Mus musculus)
PDH E1 [mitochondrial matrix] (Saccharomyces cerevisiae)
PDH E1 [mitochondrial matrix] (Canis familiaris)
PDH E1 [mitochondrial matrix] (Xenopus tropicalis)
PDH E1 [mitochondrial matrix] (Dictyostelium discoideum)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Homo sapiens)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Rattus norvegicus)
phosphorylated pyruvate dehydrogenase E1 complex [mitochondrial matrix] (Mus musculus)
Other forms of this molecule
TPP [peroxisomal matrix]
ThDP [mitochondrial matrix]
ThDP [cytosol]
Cross References
COMPOUND
C00068
ZINC
000008215517
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![TDP [mitochondrial matrix] icon](/icon/R-ICO-013856.svg){kind=icon}
