Reactome | Negative regulation by 'N-glycosylated CD274 [endoplasmic reticulum membrane]'

Negative regulation by 'N-glycosylated CD274 [endoplasmic reticulum membrane]'

Type

NegativeRegulation

Locations in the PathwayBrowser

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Immune System (Mus musculus)

- Adaptive Immune System (Mus musculus)
  - Regulation of T cell activation by CD28 family (Mus musculus)
    - Co-inhibition by PD-1 (Mus musculus)
      - Regulation of PD-L1(CD274) expression (Mus musculus)
        
        Regulation of PD-L1(CD274) Post-translational modification (Mus musculus)
        
        GSK3B-mediated proteasomal degradation of PD-L1(CD274) (Mus musculus)
        
        GSK3B phosphorylates CD274 (Mus musculus)
        
        Cd274 [endoplasmic reticulum membrane]

Regulation participants

Regulation type

NegativeRegulation

Regulated entity

GSK3B phosphorylates CD274

Regulator

Cd274 [endoplasmic reticulum membrane]

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