Reactome | Positive regulation by 'USP14 [cytosol]'

Positive regulation by 'USP14 [cytosol]'

Type

PositiveRegulation

Locations in the PathwayBrowser

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Immune System (Mus musculus)

- Cytokine Signaling in Immune system (Mus musculus)
  - Signaling by Interleukins (Mus musculus)
    - Interleukin-1 family signaling (Mus musculus)
      - Interleukin-1 signaling (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        NLRC5 binds IKBKB and CHUK (Mus musculus)
        
        Usp14 [cytosol]
- Innate Immune System (Mus musculus)
  - Toll-like Receptor Cascades (Mus musculus)
    - Toll Like Receptor 10 (TLR10) Cascade (Mus musculus)
      - MyD88 cascade initiated on plasma membrane (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        NLRC5 binds IKBKB and CHUK (Mus musculus)
        
        Usp14 [cytosol]
    - Toll Like Receptor 2 (TLR2) Cascade (Mus musculus)
      - Toll Like Receptor TLR1:TLR2 Cascade (Mus musculus)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        NLRC5 binds IKBKB and CHUK (Mus musculus)
        
        Usp14 [cytosol]
      - Toll Like Receptor TLR6:TLR2 Cascade (Mus musculus)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        NLRC5 binds IKBKB and CHUK (Mus musculus)
        
        Usp14 [cytosol]
    - Toll Like Receptor 3 (TLR3) Cascade (Mus musculus)
      - TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        NLRC5 binds IKBKB and CHUK (Mus musculus)
        
        Usp14 [cytosol]
    - Toll Like Receptor 4 (TLR4) Cascade (Mus musculus)
      - MyD88-independent TLR4 cascade (Mus musculus)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        NLRC5 binds IKBKB and CHUK (Mus musculus)
        
        Usp14 [cytosol]
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        NLRC5 binds IKBKB and CHUK (Mus musculus)
        
        Usp14 [cytosol]
    - Toll Like Receptor 5 (TLR5) Cascade (Mus musculus)
      - MyD88 cascade initiated on plasma membrane (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        NLRC5 binds IKBKB and CHUK (Mus musculus)
        
        Usp14 [cytosol]
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Mus musculus)
      - MyD88 dependent cascade initiated on endosome (Mus musculus)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        NLRC5 binds IKBKB and CHUK (Mus musculus)
        
        Usp14 [cytosol]
    - Toll Like Receptor 9 (TLR9) Cascade (Mus musculus)
      - MyD88 dependent cascade initiated on endosome (Mus musculus)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        NLRC5 binds IKBKB and CHUK (Mus musculus)
        
        Usp14 [cytosol]

Regulation participants

Regulation type

PositiveRegulation

Regulated entity

NLRC5 binds IKBKB and CHUK

Regulator

Usp14 [cytosol]