A new research article titled “The reactome pathway knowledgebase” has been published in the forthcoming 2020 NAR Database Issue. The paper describes annotating the molecular mechanisms of drug action, ...
... transcripts of genes related to immune response andcytokine production. Single cell transcriptomics showed that the Reactome Interferon signaling pathway is enriched in plasmacytoid B cells, B cells, and ...
... CD (S2FCD) - through multi-omics and functional analyses of patient-derived organoids. Reactome pathway enrichment analysis revealed subtype-specific dysregulations. In IDICD, the Nuclear receptor transcription ...
In the May 2024 issue of NPJ Precision Oncology, Cyberski et al. used Reactome’s hierarchically arranged pathways with their in silico Pathway Activation Network Decomposition Analysis (iPANDA) algorithm ...
We provide an endpoint to retrieve the full event hierarchy for a given species. For example, you can get human data with a token like the one below. Please replace “your_analysis_token” in the URL below ...
... of the token produced during every analysis, it is possible to link back to the PathwayBrowser and browse the results overlaid on either the pathways overview or a selected pathway.
As mentioned afore, ...
... Pathways’ button on the Homepage. In the next page, click the ‘Analysis’ button on the top right:
Alternatively, select the ‘Analyze Data’ button on the Homepage:
This opens a submission form, ...
... perform a standard gene set enrichment analysis, based only on the gene list. In the results overview, pathways will be greyed out if they are not significantly enriched. If a pathway is enriched, its ...
... 9 to 14, they identified co-methylation networks linked to cognitive improvements and structural brain changes. Pathway analysis using Reactome revealed that these networks are enriched in neuronal-related ...
Reactome is pleased to announce a partnership with PharmGKB to curate pharmacokinetic / Drug ADME (absorption distribution metabolism excretion) pathways. Sharing knowledge and distributing curation ...