{
  "dbId" : 10729694,
  "stableId" : "R-XTR-354192",
  "displayName" : "Integrin signaling",
  "nodes" : [ {
    "id" : 26561,
    "reactomeId" : 10668443,
    "displayName" : "Integrin alphaIIb beta3 ECM ligands",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1140,
      "y" : 17
    },
    "minX" : 1078,
    "maxX" : 1206,
    "minY" : 0,
    "maxY" : 115,
    "prop" : {
      "x" : 1078,
      "y" : 0,
      "width" : 125,
      "height" : 35
    },
    "textPosition" : {
      "x" : 1078,
      "y" : 0
    },
    "connectors" : [ {
      "edgeId" : 26560,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1151,
          "y" : 41
        },
        "to" : {
          "x" : 1206,
          "y" : 115
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26562,
    "reactomeId" : 377604,
    "displayName" : "Integrin binding divalent cations",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1095,
      "y" : 78
    },
    "minX" : 1042,
    "maxX" : 1206,
    "minY" : 57,
    "maxY" : 115,
    "prop" : {
      "x" : 1042,
      "y" : 57,
      "width" : 106,
      "height" : 43
    },
    "textPosition" : {
      "x" : 1040,
      "y" : 54
    },
    "connectors" : [ {
      "edgeId" : 26560,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1154,
          "y" : 95
        },
        "to" : {
          "x" : 1206,
          "y" : 115
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26563,
    "reactomeId" : 10668445,
    "displayName" : "Focal complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1243,
      "y" : 148
    },
    "minX" : 1194,
    "maxX" : 1421,
    "minY" : 132,
    "maxY" : 210,
    "prop" : {
      "x" : 1194,
      "y" : 138,
      "width" : 98,
      "height" : 21
    },
    "textPosition" : {
      "x" : 1195,
      "y" : 138
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1292,
          "y" : 138
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1292,
          "y" : 138
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26560,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 26564,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1273,
          "y" : 162
        },
        "to" : {
          "x" : 1421,
          "y" : 210
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26565,
    "reactomeId" : 10668435,
    "displayName" : "Integrin alphaIIb beta3:p-Y530-SRC:CSK",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1373,
      "y" : 141
    },
    "minX" : 1308,
    "maxX" : 1445,
    "minY" : 110,
    "maxY" : 210,
    "prop" : {
      "x" : 1308,
      "y" : 116,
      "width" : 131,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1311,
      "y" : 117
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1439,
          "y" : 116
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1439,
          "y" : 116
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26564,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1390,
          "y" : 169
        },
        "to" : {
          "x" : 1421,
          "y" : 210
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26566,
    "reactomeId" : 10669241,
    "displayName" : "Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1528,
      "y" : 149
    },
    "minX" : 1463,
    "maxX" : 1600,
    "minY" : 104,
    "maxY" : 188,
    "prop" : {
      "x" : 1463,
      "y" : 110,
      "width" : 131,
      "height" : 78
    },
    "textPosition" : {
      "x" : 1463,
      "y" : 111
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1594,
          "y" : 110
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1594,
          "y" : 110
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26564,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 26567,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26568,
    "reactomeId" : 10669247,
    "displayName" : "Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1785,
      "y" : 144
    },
    "minX" : 1662,
    "maxX" : 1887,
    "minY" : 99,
    "maxY" : 188,
    "prop" : {
      "x" : 1720,
      "y" : 105,
      "width" : 130,
      "height" : 78
    },
    "textPosition" : {
      "x" : 1720,
      "y" : 106
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1850,
          "y" : 105
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1850,
          "y" : 105
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26567,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1717,
          "y" : 161
        },
        "to" : {
          "x" : 1662,
          "y" : 178
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1712,
          "y" : 167
        },
        "b" : {
          "x" : 1717,
          "y" : 161
        },
        "c" : {
          "x" : 1709,
          "y" : 159
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1709,
          "y" : 159
        }
      }
    }, {
      "edgeId" : 26570,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1853,
          "y" : 172
        },
        "to" : {
          "x" : 1887,
          "y" : 188
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26569,
    "reactomeId" : 10665898,
    "displayName" : "CSK",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1750,
      "y" : 229
    },
    "minX" : 1662,
    "maxX" : 1774,
    "minY" : 178,
    "maxY" : 240,
    "prop" : {
      "x" : 1733,
      "y" : 219,
      "width" : 35,
      "height" : 21
    },
    "textPosition" : {
      "x" : 1735,
      "y" : 219
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1768,
          "y" : 219
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1768,
          "y" : 219
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26567,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1730,
          "y" : 218
        },
        "to" : {
          "x" : 1662,
          "y" : 178
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1690,
            "y" : 192
          },
          "b" : {
            "x" : 1702,
            "y" : 204
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1696,
            "y" : 198
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1722,
          "y" : 218
        },
        "b" : {
          "x" : 1730,
          "y" : 218
        },
        "c" : {
          "x" : 1726,
          "y" : 211
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1726,
          "y" : 211
        }
      }
    } ]
  }, {
    "id" : 26571,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1854,
      "y" : 230
    },
    "minX" : 1833,
    "maxX" : 1887,
    "minY" : 188,
    "maxY" : 245,
    "prop" : {
      "x" : 1833,
      "y" : 216,
      "width" : 43,
      "height" : 29
    },
    "textPosition" : {
      "x" : 1837,
      "y" : 220
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1871,
          "y" : 221
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1871,
          "y" : 221
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26570,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1865,
          "y" : 213
        },
        "to" : {
          "x" : 1887,
          "y" : 188
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1870,
            "y" : 194
          },
          "b" : {
            "x" : 1882,
            "y" : 206
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1876,
            "y" : 200
          }
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 26572,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2004,
      "y" : 238
    },
    "minX" : 1958,
    "maxX" : 2025,
    "minY" : 188,
    "maxY" : 252,
    "prop" : {
      "x" : 1984,
      "y" : 224,
      "width" : 40,
      "height" : 28
    },
    "textPosition" : {
      "x" : 1994,
      "y" : 227
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2019,
          "y" : 229
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2019,
          "y" : 229
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26570,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1991,
          "y" : 221
        },
        "to" : {
          "x" : 1958,
          "y" : 188
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1968,
            "y" : 198
          },
          "b" : {
            "x" : 1980,
            "y" : 210
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1974,
            "y" : 204
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1983,
          "y" : 219
        },
        "b" : {
          "x" : 1991,
          "y" : 221
        },
        "c" : {
          "x" : 1989,
          "y" : 213
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1989,
          "y" : 213
        }
      }
    } ]
  }, {
    "id" : 26573,
    "reactomeId" : 10669227,
    "displayName" : "Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2053,
      "y" : 145
    },
    "minX" : 1958,
    "maxX" : 2160,
    "minY" : 107,
    "maxY" : 188,
    "prop" : {
      "x" : 1988,
      "y" : 113,
      "width" : 130,
      "height" : 64
    },
    "textPosition" : {
      "x" : 1988,
      "y" : 114
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2118,
          "y" : 113
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2118,
          "y" : 113
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26592,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2121,
          "y" : 156
        },
        "to" : {
          "x" : 2160,
          "y" : 164
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 26570,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1985,
          "y" : 174
        },
        "to" : {
          "x" : 1958,
          "y" : 188
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1981,
          "y" : 181
        },
        "b" : {
          "x" : 1985,
          "y" : 174
        },
        "c" : {
          "x" : 1977,
          "y" : 174
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1977,
          "y" : 174
        }
      }
    } ]
  }, {
    "id" : 26574,
    "reactomeId" : 10669249,
    "displayName" : "PTPN1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1922,
      "y" : 263
    },
    "minX" : 1896,
    "maxX" : 1955,
    "minY" : 196,
    "maxY" : 274,
    "prop" : {
      "x" : 1896,
      "y" : 253,
      "width" : 53,
      "height" : 21
    },
    "textPosition" : {
      "x" : 1898,
      "y" : 253
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1949,
          "y" : 253
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1949,
          "y" : 253
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26570,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1922,
          "y" : 250
        },
        "to" : {
          "x" : 1922,
          "y" : 204
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1922,
          "y" : 200
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1922,
          "y" : 200
        }
      }
    } ]
  }, {
    "id" : 26576,
    "reactomeId" : 10672189,
    "displayName" : "Rap1 cAMP-GEFs",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 165,
      "y" : 258
    },
    "minX" : 103,
    "maxX" : 228,
    "minY" : 188,
    "maxY" : 269,
    "prop" : {
      "x" : 103,
      "y" : 248,
      "width" : 125,
      "height" : 21
    },
    "textPosition" : {
      "x" : 109,
      "y" : 248
    },
    "connectors" : [ {
      "edgeId" : 26575,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 165,
          "y" : 242
        },
        "to" : {
          "x" : 167,
          "y" : 196
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 167,
          "y" : 192
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 167,
          "y" : 192
        }
      }
    } ]
  }, {
    "id" : 26578,
    "reactomeId" : 10658341,
    "displayName" : "Integrin alphaIIb:beta3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 53,
      "y" : 484
    },
    "minX" : 0,
    "maxX" : 113,
    "minY" : 459,
    "maxY" : 503,
    "prop" : {
      "x" : 0,
      "y" : 465,
      "width" : 107,
      "height" : 38
    },
    "textPosition" : {
      "x" : 4,
      "y" : 468
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 107,
          "y" : 465
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 107,
          "y" : 465
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26577,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26579,
    "reactomeId" : 10674658,
    "displayName" : "Integrin alpha IIb p(T779)-beta 3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 71,
      "y" : 335
    },
    "minX" : 0,
    "maxX" : 149,
    "minY" : 310,
    "maxY" : 354,
    "prop" : {
      "x" : 0,
      "y" : 316,
      "width" : 143,
      "height" : 38
    },
    "textPosition" : {
      "x" : 9,
      "y" : 319
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 143,
          "y" : 316
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 143,
          "y" : 316
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26577,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26580,
    "reactomeId" : 10657160,
    "displayName" : "PDPK1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 137,
      "y" : 402
    },
    "minX" : 64,
    "maxX" : 188,
    "minY" : 386,
    "maxY" : 413,
    "prop" : {
      "x" : 93,
      "y" : 392,
      "width" : 89,
      "height" : 21
    },
    "textPosition" : {
      "x" : 113,
      "y" : 392
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 182,
          "y" : 392
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 182,
          "y" : 392
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26577,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 87,
          "y" : 401
        },
        "to" : {
          "x" : 72,
          "y" : 401
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 68,
          "y" : 401
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 68,
          "y" : 401
        }
      }
    } ]
  }, {
    "id" : 26582,
    "reactomeId" : 10675206,
    "displayName" : "Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1222,
      "y" : 827
    },
    "minX" : 1160,
    "maxX" : 1291,
    "minY" : 790,
    "maxY" : 859,
    "prop" : {
      "x" : 1160,
      "y" : 796,
      "width" : 125,
      "height" : 63
    },
    "textPosition" : {
      "x" : 1158,
      "y" : 796
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1285,
          "y" : 796
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1285,
          "y" : 796
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26581,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26583,
    "reactomeId" : 10675208,
    "displayName" : "Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1026,
      "y" : 826
    },
    "minX" : 963,
    "maxX" : 1096,
    "minY" : 782,
    "maxY" : 864,
    "prop" : {
      "x" : 963,
      "y" : 788,
      "width" : 127,
      "height" : 76
    },
    "textPosition" : {
      "x" : 962,
      "y" : 787
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1090,
          "y" : 788
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1090,
          "y" : 788
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26581,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26585,
    "reactomeId" : 10658508,
    "displayName" : "SYK",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1595,
      "y" : 557
    },
    "minX" : 1578,
    "maxX" : 1648,
    "minY" : 541,
    "maxY" : 602,
    "prop" : {
      "x" : 1578,
      "y" : 547,
      "width" : 35,
      "height" : 21
    },
    "textPosition" : {
      "x" : 1580,
      "y" : 547
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1613,
          "y" : 547
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1613,
          "y" : 547
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26584,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1607,
          "y" : 571
        },
        "to" : {
          "x" : 1648,
          "y" : 602
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1621,
            "y" : 580
          },
          "b" : {
            "x" : 1633,
            "y" : 592
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1627,
            "y" : 586
          }
        }
      }
    } ]
  }, {
    "id" : 26586,
    "reactomeId" : 10669234,
    "displayName" : "Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2351,
      "y" : 138
    },
    "minX" : 1648,
    "maxX" : 2422,
    "minY" : 94,
    "maxY" : 602,
    "prop" : {
      "x" : 2287,
      "y" : 100,
      "width" : 129,
      "height" : 76
    },
    "textPosition" : {
      "x" : 2287,
      "y" : 99
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2416,
          "y" : 100
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2416,
          "y" : 100
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26592,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2284,
          "y" : 151
        },
        "to" : {
          "x" : 2222,
          "y" : 164
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2278,
          "y" : 156
        },
        "b" : {
          "x" : 2284,
          "y" : 151
        },
        "c" : {
          "x" : 2276,
          "y" : 149
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2276,
          "y" : 149
        }
      }
    }, {
      "edgeId" : 26584,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2329,
          "y" : 179
        },
        "to" : {
          "x" : 2221,
          "y" : 367
        }
      }, {
        "from" : {
          "x" : 2221,
          "y" : 367
        },
        "to" : {
          "x" : 1648,
          "y" : 602
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26587,
    "reactomeId" : 10674238,
    "displayName" : "Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1652,
      "y" : 820
    },
    "minX" : 1513,
    "maxX" : 1719,
    "minY" : 777,
    "maxY" : 858,
    "prop" : {
      "x" : 1592,
      "y" : 783,
      "width" : 121,
      "height" : 75
    },
    "textPosition" : {
      "x" : 1593,
      "y" : 781
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1713,
          "y" : 783
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1713,
          "y" : 783
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26584,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 26588,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1589,
          "y" : 799
        },
        "to" : {
          "x" : 1544,
          "y" : 783
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 26588,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1589,
          "y" : 819
        },
        "to" : {
          "x" : 1516,
          "y" : 819
        }
      }, {
        "from" : {
          "x" : 1516,
          "y" : 819
        },
        "to" : {
          "x" : 1517,
          "y" : 799
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1517,
          "y" : 795
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1517,
          "y" : 795
        }
      }
    } ]
  }, {
    "id" : 26589,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1583,
      "y" : 739
    },
    "minX" : 1544,
    "maxX" : 1606,
    "minY" : 724,
    "maxY" : 783,
    "prop" : {
      "x" : 1562,
      "y" : 725,
      "width" : 43,
      "height" : 29
    },
    "textPosition" : {
      "x" : 1568,
      "y" : 729
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1600,
          "y" : 730
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1600,
          "y" : 730
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26588,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1570,
          "y" : 757
        },
        "to" : {
          "x" : 1544,
          "y" : 783
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1551,
            "y" : 764
          },
          "b" : {
            "x" : 1563,
            "y" : 776
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1557,
            "y" : 770
          }
        }
      }
    } ]
  }, {
    "id" : 26590,
    "reactomeId" : 10674245,
    "displayName" : "Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1395,
      "y" : 828
    },
    "minX" : 1333,
    "maxX" : 1493,
    "minY" : 783,
    "maxY" : 867,
    "prop" : {
      "x" : 1333,
      "y" : 790,
      "width" : 125,
      "height" : 77
    },
    "textPosition" : {
      "x" : 1331,
      "y" : 790
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1458,
          "y" : 790
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1458,
          "y" : 790
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26588,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1461,
          "y" : 799
        },
        "to" : {
          "x" : 1493,
          "y" : 783
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1465,
          "y" : 792
        },
        "b" : {
          "x" : 1461,
          "y" : 799
        },
        "c" : {
          "x" : 1469,
          "y" : 799
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1469,
          "y" : 799
        }
      }
    } ]
  }, {
    "id" : 26591,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1447,
      "y" : 734
    },
    "minX" : 1426,
    "maxX" : 1493,
    "minY" : 719,
    "maxY" : 783,
    "prop" : {
      "x" : 1426,
      "y" : 720,
      "width" : 43,
      "height" : 29
    },
    "textPosition" : {
      "x" : 1431,
      "y" : 724
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1464,
          "y" : 725
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1464,
          "y" : 725
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26588,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1460,
          "y" : 752
        },
        "to" : {
          "x" : 1493,
          "y" : 783
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1470,
            "y" : 761
          },
          "b" : {
            "x" : 1482,
            "y" : 773
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1476,
            "y" : 767
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1468,
          "y" : 754
        },
        "b" : {
          "x" : 1460,
          "y" : 752
        },
        "c" : {
          "x" : 1462,
          "y" : 760
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1462,
          "y" : 760
        }
      }
    } ]
  }, {
    "id" : 26593,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2140,
      "y" : 209
    },
    "minX" : 2119,
    "maxX" : 2163,
    "minY" : 164,
    "maxY" : 224,
    "prop" : {
      "x" : 2119,
      "y" : 195,
      "width" : 43,
      "height" : 29
    },
    "textPosition" : {
      "x" : 2125,
      "y" : 199
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2157,
          "y" : 200
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2157,
          "y" : 200
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26592,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2146,
          "y" : 192
        },
        "to" : {
          "x" : 2160,
          "y" : 164
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 2147,
            "y" : 172
          },
          "b" : {
            "x" : 2159,
            "y" : 184
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2153,
            "y" : 178
          }
        }
      }
    } ]
  }, {
    "id" : 26594,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2253,
      "y" : 209
    },
    "minX" : 2222,
    "maxX" : 2276,
    "minY" : 164,
    "maxY" : 224,
    "prop" : {
      "x" : 2232,
      "y" : 195,
      "width" : 43,
      "height" : 29
    },
    "textPosition" : {
      "x" : 2237,
      "y" : 199
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2270,
          "y" : 200
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2270,
          "y" : 200
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26592,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2243,
          "y" : 192
        },
        "to" : {
          "x" : 2222,
          "y" : 164
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 2226,
            "y" : 172
          },
          "b" : {
            "x" : 2238,
            "y" : 184
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2232,
            "y" : 178
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 2236,
          "y" : 189
        },
        "b" : {
          "x" : 2243,
          "y" : 192
        },
        "c" : {
          "x" : 2242,
          "y" : 184
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2242,
          "y" : 184
        }
      }
    } ]
  }, {
    "id" : 26595,
    "reactomeId" : 10663666,
    "displayName" : "SRC-2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2192,
      "y" : 238
    },
    "minX" : 2170,
    "maxX" : 2221,
    "minY" : 172,
    "maxY" : 249,
    "prop" : {
      "x" : 2170,
      "y" : 227,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2170,
      "y" : 227
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2215,
          "y" : 227
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2215,
          "y" : 227
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26592,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2192,
          "y" : 224
        },
        "to" : {
          "x" : 2192,
          "y" : 180
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2192,
          "y" : 176
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2192,
          "y" : 176
        }
      }
    } ]
  }, {
    "id" : 26545,
    "reactomeId" : 10668449,
    "displayName" : "RAP1:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 56,
      "y" : 145
    },
    "minX" : 16,
    "maxX" : 129,
    "minY" : 129,
    "maxY" : 179,
    "prop" : {
      "x" : 16,
      "y" : 135,
      "width" : 80,
      "height" : 21
    },
    "textPosition" : {
      "x" : 21,
      "y" : 135
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 96,
          "y" : 135
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 96,
          "y" : 135
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26575,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 78,
          "y" : 159
        },
        "to" : {
          "x" : 129,
          "y" : 179
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 26544,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 91,
          "y" : 159
        },
        "to" : {
          "x" : 123,
          "y" : 165
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26546,
    "reactomeId" : 29438,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 73,
      "y" : 224
    },
    "minX" : 52,
    "maxX" : 129,
    "minY" : 165,
    "maxY" : 239,
    "prop" : {
      "x" : 52,
      "y" : 210,
      "width" : 43,
      "height" : 29
    },
    "textPosition" : {
      "x" : 57,
      "y" : 214
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 90,
          "y" : 215
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 90,
          "y" : 215
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26575,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 91,
          "y" : 207
        },
        "to" : {
          "x" : 129,
          "y" : 179
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 26544,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 85,
          "y" : 207
        },
        "to" : {
          "x" : 123,
          "y" : 165
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26547,
    "reactomeId" : 29420,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 230,
      "y" : 222
    },
    "minX" : 181,
    "maxX" : 253,
    "minY" : 165,
    "maxY" : 237,
    "prop" : {
      "x" : 209,
      "y" : 208,
      "width" : 43,
      "height" : 29
    },
    "textPosition" : {
      "x" : 213,
      "y" : 212
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 247,
          "y" : 213
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 247,
          "y" : 213
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26575,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 223,
          "y" : 205
        },
        "to" : {
          "x" : 210,
          "y" : 180
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 216,
          "y" : 201
        },
        "b" : {
          "x" : 223,
          "y" : 205
        },
        "c" : {
          "x" : 223,
          "y" : 197
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 223,
          "y" : 197
        }
      }
    }, {
      "edgeId" : 26544,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 217,
          "y" : 205
        },
        "to" : {
          "x" : 181,
          "y" : 165
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 209,
          "y" : 203
        },
        "b" : {
          "x" : 217,
          "y" : 205
        },
        "c" : {
          "x" : 215,
          "y" : 197
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 215,
          "y" : 197
        }
      }
    } ]
  }, {
    "id" : 26548,
    "reactomeId" : 10668414,
    "displayName" : "RAP1:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 260,
      "y" : 152
    },
    "minX" : 181,
    "maxX" : 348,
    "minY" : 136,
    "maxY" : 194,
    "prop" : {
      "x" : 220,
      "y" : 142,
      "width" : 80,
      "height" : 21
    },
    "textPosition" : {
      "x" : 226,
      "y" : 142
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 300,
          "y" : 142
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 300,
          "y" : 142
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26575,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 241,
          "y" : 166
        },
        "to" : {
          "x" : 210,
          "y" : 180
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 236,
          "y" : 172
        },
        "b" : {
          "x" : 241,
          "y" : 166
        },
        "c" : {
          "x" : 233,
          "y" : 165
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 233,
          "y" : 165
        }
      }
    }, {
      "edgeId" : 26544,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 217,
          "y" : 158
        },
        "to" : {
          "x" : 181,
          "y" : 165
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 211,
          "y" : 163
        },
        "b" : {
          "x" : 217,
          "y" : 158
        },
        "c" : {
          "x" : 209,
          "y" : 155
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 209,
          "y" : 155
        }
      }
    }, {
      "edgeId" : 26550,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 282,
          "y" : 166
        },
        "to" : {
          "x" : 348,
          "y" : 194
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26549,
    "reactomeId" : 10668461,
    "displayName" : "CalDAG-GEFs:DAG:Ca2+",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 152,
      "y" : 91
    },
    "minX" : 91,
    "maxX" : 220,
    "minY" : 67,
    "maxY" : 157,
    "prop" : {
      "x" : 91,
      "y" : 73,
      "width" : 123,
      "height" : 36
    },
    "textPosition" : {
      "x" : 91,
      "y" : 74
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 214,
          "y" : 73
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 214,
          "y" : 73
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26544,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 152,
          "y" : 112
        },
        "to" : {
          "x" : 153,
          "y" : 149
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 153,
          "y" : 153
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 153,
          "y" : 153
        }
      }
    } ]
  }, {
    "id" : 26551,
    "reactomeId" : 179856,
    "displayName" : "PI(4,5)P2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 342,
      "y" : 149
    },
    "minX" : 310,
    "maxX" : 375,
    "minY" : 129,
    "maxY" : 194,
    "prop" : {
      "x" : 310,
      "y" : 130,
      "width" : 64,
      "height" : 38
    },
    "textPosition" : {
      "x" : 317,
      "y" : 131
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 369,
          "y" : 135
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 369,
          "y" : 135
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26550,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 344,
          "y" : 171
        },
        "to" : {
          "x" : 348,
          "y" : 194
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26552,
    "reactomeId" : 10668418,
    "displayName" : "apbb1ip",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 322,
      "y" : 226
    },
    "minX" : 292,
    "maxX" : 358,
    "minY" : 194,
    "maxY" : 237,
    "prop" : {
      "x" : 292,
      "y" : 215,
      "width" : 60,
      "height" : 22
    },
    "textPosition" : {
      "x" : 292,
      "y" : 215
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 352,
          "y" : 215
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 352,
          "y" : 215
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26550,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 330,
          "y" : 212
        },
        "to" : {
          "x" : 348,
          "y" : 194
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26553,
    "reactomeId" : 10668420,
    "displayName" : "Rap1-GTP:PIP2:RIAM",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 451,
      "y" : 147
    },
    "minX" : 398,
    "maxX" : 518,
    "minY" : 124,
    "maxY" : 173,
    "prop" : {
      "x" : 398,
      "y" : 130,
      "width" : 107,
      "height" : 35
    },
    "textPosition" : {
      "x" : 400,
      "y" : 130
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 505,
          "y" : 130
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 505,
          "y" : 130
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26550,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 26554,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 496,
          "y" : 168
        },
        "to" : {
          "x" : 518,
          "y" : 173
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26555,
    "reactomeId" : 10668426,
    "displayName" : "tln1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 472,
      "y" : 199
    },
    "minX" : 446,
    "maxX" : 518,
    "minY" : 173,
    "maxY" : 210,
    "prop" : {
      "x" : 446,
      "y" : 189,
      "width" : 53,
      "height" : 21
    },
    "textPosition" : {
      "x" : 456,
      "y" : 189
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 499,
          "y" : 189
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 499,
          "y" : 189
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26554,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 490,
          "y" : 186
        },
        "to" : {
          "x" : 518,
          "y" : 173
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26556,
    "reactomeId" : 10668428,
    "displayName" : "Talin:RIAM complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 595,
      "y" : 141
    },
    "minX" : 555,
    "maxX" : 702,
    "minY" : 120,
    "maxY" : 261,
    "prop" : {
      "x" : 555,
      "y" : 126,
      "width" : 81,
      "height" : 31
    },
    "textPosition" : {
      "x" : 558,
      "y" : 122
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 636,
          "y" : 126
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 636,
          "y" : 126
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26554,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 26557,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 608,
          "y" : 160
        },
        "to" : {
          "x" : 702,
          "y" : 261
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26558,
    "reactomeId" : 10668435,
    "displayName" : "Integrin alphaIIb beta3:p-Y530-SRC:CSK",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 699,
      "y" : 143
    },
    "minX" : 646,
    "maxX" : 758,
    "minY" : 113,
    "maxY" : 261,
    "prop" : {
      "x" : 646,
      "y" : 119,
      "width" : 106,
      "height" : 48
    },
    "textPosition" : {
      "x" : 646,
      "y" : 118
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 752,
          "y" : 119
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 752,
          "y" : 119
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26557,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 699,
          "y" : 170
        },
        "to" : {
          "x" : 702,
          "y" : 261
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26559,
    "reactomeId" : 10668437,
    "displayName" : "Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1087,
      "y" : 147
    },
    "minX" : 1024,
    "maxX" : 1206,
    "minY" : 111,
    "maxY" : 177,
    "prop" : {
      "x" : 1024,
      "y" : 117,
      "width" : 126,
      "height" : 60
    },
    "textPosition" : {
      "x" : 1025,
      "y" : 114
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1150,
          "y" : 117
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1150,
          "y" : 117
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26560,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1153,
          "y" : 130
        },
        "to" : {
          "x" : 1206,
          "y" : 115
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 26557,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 26592,
    "reactomeId" : 10669239,
    "displayName" : "Autophosphorylation of SRC",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2192,
      "y" : 164
    },
    "minX" : 2160,
    "maxX" : 2222,
    "minY" : 158,
    "maxY" : 170,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2160,
        "y" : 164
      },
      "to" : {
        "x" : 2192,
        "y" : 164
      }
    }, {
      "from" : {
        "x" : 2192,
        "y" : 164
      },
      "to" : {
        "x" : 2222,
        "y" : 164
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2186,
        "y" : 158
      },
      "b" : {
        "x" : 2198,
        "y" : 170
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2192,
        "y" : 164
      }
    },
    "inputs" : [ {
      "id" : 26593,
      "points" : [ {
        "x" : 2146,
        "y" : 192
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 26573,
      "points" : [ {
        "x" : 2121,
        "y" : 156
      } ]
    } ],
    "outputs" : [ {
      "id" : 26594,
      "points" : [ {
        "x" : 2243,
        "y" : 192
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 26586,
      "points" : [ {
        "x" : 2284,
        "y" : 151
      } ]
    } ],
    "catalysts" : [ {
      "id" : 26595,
      "points" : [ {
        "x" : 2192,
        "y" : 224
      } ]
    } ]
  }, {
    "id" : 26560,
    "reactomeId" : 10668447,
    "displayName" : "Interaction of integrin alphaIIb beta3 with Fibrinogen",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1237,
      "y" : 116
    },
    "minX" : 1206,
    "maxX" : 1243,
    "minY" : 110,
    "maxY" : 135,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1206,
        "y" : 115
      },
      "to" : {
        "x" : 1237,
        "y" : 116
      }
    }, {
      "from" : {
        "x" : 1237,
        "y" : 116
      },
      "to" : {
        "x" : 1241,
        "y" : 135
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1236,
        "y" : 129
      },
      "b" : {
        "x" : 1241,
        "y" : 135
      },
      "c" : {
        "x" : 1243,
        "y" : 127
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1243,
        "y" : 127
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1237,
        "y" : 116
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1237,
        "y" : 116
      }
    },
    "inputs" : [ {
      "id" : 26561,
      "points" : [ {
        "x" : 1151,
        "y" : 41
      } ]
    }, {
      "id" : 26559,
      "points" : [ {
        "x" : 1153,
        "y" : 130
      } ]
    }, {
      "id" : 26562,
      "points" : [ {
        "x" : 1154,
        "y" : 95
      } ]
    } ],
    "outputs" : [ {
      "id" : 26563
    } ]
  }, {
    "id" : 26564,
    "reactomeId" : 10669243,
    "displayName" : "Clustering of Integrin alphaIIb beta3 complexes",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1457,
      "y" : 210
    },
    "minX" : 1421,
    "maxX" : 1482,
    "minY" : 191,
    "maxY" : 216,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1421,
        "y" : 210
      },
      "to" : {
        "x" : 1457,
        "y" : 210
      }
    }, {
      "from" : {
        "x" : 1457,
        "y" : 210
      },
      "to" : {
        "x" : 1482,
        "y" : 191
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1479,
        "y" : 198
      },
      "b" : {
        "x" : 1482,
        "y" : 191
      },
      "c" : {
        "x" : 1474,
        "y" : 192
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1474,
        "y" : 192
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1457,
        "y" : 210
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1457,
        "y" : 210
      }
    },
    "inputs" : [ {
      "id" : 26563,
      "points" : [ {
        "x" : 1273,
        "y" : 162
      } ]
    }, {
      "id" : 26565,
      "points" : [ {
        "x" : 1390,
        "y" : 169
      } ]
    } ],
    "outputs" : [ {
      "id" : 26566
    } ]
  }, {
    "id" : 26567,
    "reactomeId" : 10669254,
    "displayName" : "Release of CSK from SRC",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1625,
      "y" : 179
    },
    "minX" : 1597,
    "maxX" : 1662,
    "minY" : 169,
    "maxY" : 185,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 1597,
        "y" : 169
      },
      "to" : {
        "x" : 1625,
        "y" : 179
      }
    }, {
      "from" : {
        "x" : 1625,
        "y" : 179
      },
      "to" : {
        "x" : 1662,
        "y" : 178
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 1625,
        "y" : 179
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 1625,
        "y" : 179
      }
    },
    "inputs" : [ {
      "id" : 26566
    } ],
    "outputs" : [ {
      "id" : 26568,
      "points" : [ {
        "x" : 1717,
        "y" : 161
      } ]
    }, {
      "id" : 26569,
      "points" : [ {
        "x" : 1730,
        "y" : 218
      } ],
      "stoichiometry" : 2
    } ]
  }, {
    "id" : 26570,
    "reactomeId" : 10669252,
    "displayName" : "Dephosphorylation of inactive SRC by PTPB1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1922,
      "y" : 188
    },
    "minX" : 1887,
    "maxX" : 1958,
    "minY" : 182,
    "maxY" : 194,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1887,
        "y" : 188
      },
      "to" : {
        "x" : 1922,
        "y" : 188
      }
    }, {
      "from" : {
        "x" : 1922,
        "y" : 188
      },
      "to" : {
        "x" : 1958,
        "y" : 188
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1916,
        "y" : 182
      },
      "b" : {
        "x" : 1928,
        "y" : 194
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1922,
        "y" : 188
      }
    },
    "inputs" : [ {
      "id" : 26571,
      "points" : [ {
        "x" : 1865,
        "y" : 213
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 26568,
      "points" : [ {
        "x" : 1853,
        "y" : 172
      } ]
    } ],
    "outputs" : [ {
      "id" : 26572,
      "points" : [ {
        "x" : 1991,
        "y" : 221
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 26573,
      "points" : [ {
        "x" : 1985,
        "y" : 174
      } ]
    } ],
    "catalysts" : [ {
      "id" : 26574,
      "points" : [ {
        "x" : 1922,
        "y" : 250
      } ]
    } ]
  }, {
    "id" : 26575,
    "reactomeId" : 10678789,
    "displayName" : "Activation of Rap1 by membrane-associated GEFs",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 168,
      "y" : 180
    },
    "minX" : 129,
    "maxX" : 210,
    "minY" : 174,
    "maxY" : 186,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 129,
        "y" : 179
      },
      "to" : {
        "x" : 168,
        "y" : 180
      }
    }, {
      "from" : {
        "x" : 168,
        "y" : 180
      },
      "to" : {
        "x" : 210,
        "y" : 180
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 162,
        "y" : 174
      },
      "b" : {
        "x" : 174,
        "y" : 186
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 168,
        "y" : 180
      }
    },
    "inputs" : [ {
      "id" : 26545,
      "points" : [ {
        "x" : 78,
        "y" : 159
      } ]
    }, {
      "id" : 26546,
      "points" : [ {
        "x" : 91,
        "y" : 207
      } ]
    } ],
    "outputs" : [ {
      "id" : 26548,
      "points" : [ {
        "x" : 241,
        "y" : 166
      } ]
    }, {
      "id" : 26547,
      "points" : [ {
        "x" : 223,
        "y" : 205
      } ]
    } ],
    "catalysts" : [ {
      "id" : 26576,
      "points" : [ {
        "x" : 165,
        "y" : 242
      } ]
    } ]
  }, {
    "id" : 26544,
    "reactomeId" : 10668464,
    "displayName" : "Activation of Rap1 by cytosolic GEFs",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 153,
      "y" : 165
    },
    "minX" : 123,
    "maxX" : 181,
    "minY" : 159,
    "maxY" : 171,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 123,
        "y" : 165
      },
      "to" : {
        "x" : 153,
        "y" : 165
      }
    }, {
      "from" : {
        "x" : 153,
        "y" : 165
      },
      "to" : {
        "x" : 181,
        "y" : 165
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 147,
        "y" : 159
      },
      "b" : {
        "x" : 159,
        "y" : 171
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 153,
        "y" : 165
      }
    },
    "inputs" : [ {
      "id" : 26545,
      "points" : [ {
        "x" : 91,
        "y" : 159
      } ]
    }, {
      "id" : 26546,
      "points" : [ {
        "x" : 85,
        "y" : 207
      } ]
    } ],
    "outputs" : [ {
      "id" : 26547,
      "points" : [ {
        "x" : 217,
        "y" : 205
      } ]
    }, {
      "id" : 26548,
      "points" : [ {
        "x" : 217,
        "y" : 158
      } ]
    } ],
    "catalysts" : [ {
      "id" : 26549,
      "points" : [ {
        "x" : 152,
        "y" : 112
      } ]
    } ]
  }, {
    "id" : 26577,
    "reactomeId" : 10674661,
    "displayName" : "Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 56,
      "y" : 401
    },
    "minX" : 50,
    "maxX" : 66,
    "minY" : 357,
    "maxY" : 462,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 53,
        "y" : 462
      },
      "to" : {
        "x" : 56,
        "y" : 401
      }
    }, {
      "from" : {
        "x" : 56,
        "y" : 401
      },
      "to" : {
        "x" : 66,
        "y" : 357
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 68,
        "y" : 365
      },
      "b" : {
        "x" : 66,
        "y" : 357
      },
      "c" : {
        "x" : 61,
        "y" : 363
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 61,
        "y" : 363
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 50,
        "y" : 395
      },
      "b" : {
        "x" : 62,
        "y" : 407
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 56,
        "y" : 401
      }
    },
    "inputs" : [ {
      "id" : 26578
    } ],
    "outputs" : [ {
      "id" : 26579
    } ],
    "catalysts" : [ {
      "id" : 26580,
      "points" : [ {
        "x" : 87,
        "y" : 401
      } ]
    } ]
  }, {
    "id" : 26581,
    "reactomeId" : 10675210,
    "displayName" : "SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1134,
      "y" : 825
    },
    "minX" : 1093,
    "maxX" : 1157,
    "minY" : 819,
    "maxY" : 831,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1157,
        "y" : 825
      },
      "to" : {
        "x" : 1134,
        "y" : 825
      }
    }, {
      "from" : {
        "x" : 1134,
        "y" : 825
      },
      "to" : {
        "x" : 1093,
        "y" : 825
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1100,
        "y" : 821
      },
      "b" : {
        "x" : 1093,
        "y" : 825
      },
      "c" : {
        "x" : 1100,
        "y" : 829
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1100,
        "y" : 829
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1128,
        "y" : 819
      },
      "b" : {
        "x" : 1140,
        "y" : 831
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1134,
        "y" : 825
      }
    },
    "inputs" : [ {
      "id" : 26582
    } ],
    "outputs" : [ {
      "id" : 26583
    } ]
  }, {
    "id" : 26550,
    "reactomeId" : 10668422,
    "displayName" : "Translocation of RIAM to plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 386,
      "y" : 195
    },
    "minX" : 348,
    "maxX" : 427,
    "minY" : 168,
    "maxY" : 201,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 348,
        "y" : 194
      },
      "to" : {
        "x" : 386,
        "y" : 195
      }
    }, {
      "from" : {
        "x" : 386,
        "y" : 195
      },
      "to" : {
        "x" : 427,
        "y" : 168
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 423,
        "y" : 175
      },
      "b" : {
        "x" : 427,
        "y" : 168
      },
      "c" : {
        "x" : 419,
        "y" : 168
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 419,
        "y" : 168
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 386,
        "y" : 195
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 386,
        "y" : 195
      }
    },
    "inputs" : [ {
      "id" : 26551,
      "points" : [ {
        "x" : 344,
        "y" : 171
      } ]
    }, {
      "id" : 26552,
      "points" : [ {
        "x" : 330,
        "y" : 212
      } ]
    }, {
      "id" : 26548,
      "points" : [ {
        "x" : 282,
        "y" : 166
      } ]
    } ],
    "outputs" : [ {
      "id" : 26553
    } ]
  }, {
    "id" : 26584,
    "reactomeId" : 10674240,
    "displayName" : "SYK binds to integrin alphaIIb beta3",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1648,
      "y" : 643
    },
    "minX" : 1642,
    "maxX" : 1654,
    "minY" : 602,
    "maxY" : 780,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1648,
        "y" : 602
      },
      "to" : {
        "x" : 1648,
        "y" : 643
      }
    }, {
      "from" : {
        "x" : 1648,
        "y" : 643
      },
      "to" : {
        "x" : 1651,
        "y" : 780
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1647,
        "y" : 773
      },
      "b" : {
        "x" : 1651,
        "y" : 780
      },
      "c" : {
        "x" : 1655,
        "y" : 773
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1655,
        "y" : 773
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1648,
        "y" : 643
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1648,
        "y" : 643
      }
    },
    "inputs" : [ {
      "id" : 26585,
      "points" : [ {
        "x" : 1607,
        "y" : 571
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 26586,
      "points" : [ {
        "x" : 2329,
        "y" : 179
      }, {
        "x" : 2221,
        "y" : 367
      } ]
    } ],
    "outputs" : [ {
      "id" : 26587
    } ]
  }, {
    "id" : 26554,
    "reactomeId" : 10668441,
    "displayName" : "Activation of Talin",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 544,
      "y" : 173
    },
    "minX" : 518,
    "maxX" : 570,
    "minY" : 160,
    "maxY" : 179,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 518,
        "y" : 173
      },
      "to" : {
        "x" : 544,
        "y" : 173
      }
    }, {
      "from" : {
        "x" : 544,
        "y" : 173
      },
      "to" : {
        "x" : 570,
        "y" : 160
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 566,
        "y" : 167
      },
      "b" : {
        "x" : 570,
        "y" : 160
      },
      "c" : {
        "x" : 562,
        "y" : 160
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 562,
        "y" : 160
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 544,
        "y" : 173
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 544,
        "y" : 173
      }
    },
    "inputs" : [ {
      "id" : 26555,
      "points" : [ {
        "x" : 490,
        "y" : 186
      } ]
    }, {
      "id" : 26553,
      "points" : [ {
        "x" : 496,
        "y" : 168
      } ]
    } ],
    "outputs" : [ {
      "id" : 26556
    } ]
  }, {
    "id" : 26588,
    "reactomeId" : 10674248,
    "displayName" : "SYK activation by SRC",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1517,
      "y" : 783
    },
    "minX" : 1493,
    "maxX" : 1544,
    "minY" : 777,
    "maxY" : 789,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1544,
        "y" : 783
      },
      "to" : {
        "x" : 1517,
        "y" : 783
      }
    }, {
      "from" : {
        "x" : 1517,
        "y" : 783
      },
      "to" : {
        "x" : 1493,
        "y" : 783
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1511,
        "y" : 777
      },
      "b" : {
        "x" : 1523,
        "y" : 789
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1517,
        "y" : 783
      }
    },
    "inputs" : [ {
      "id" : 26587,
      "points" : [ {
        "x" : 1589,
        "y" : 799
      } ]
    }, {
      "id" : 26589,
      "points" : [ {
        "x" : 1570,
        "y" : 757
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 26590,
      "points" : [ {
        "x" : 1461,
        "y" : 799
      } ]
    }, {
      "id" : 26591,
      "points" : [ {
        "x" : 1460,
        "y" : 752
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 26587,
      "points" : [ {
        "x" : 1589,
        "y" : 819
      }, {
        "x" : 1516,
        "y" : 819
      } ]
    } ]
  }, {
    "id" : 26557,
    "reactomeId" : 10668439,
    "displayName" : "Integrin alphaIIb beta3 activation",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 775,
      "y" : 262
    },
    "minX" : 702,
    "maxX" : 1021,
    "minY" : 170,
    "maxY" : 268,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 702,
        "y" : 261
      },
      "to" : {
        "x" : 775,
        "y" : 262
      }
    }, {
      "from" : {
        "x" : 775,
        "y" : 262
      },
      "to" : {
        "x" : 1021,
        "y" : 170
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1016,
        "y" : 176
      },
      "b" : {
        "x" : 1021,
        "y" : 170
      },
      "c" : {
        "x" : 1013,
        "y" : 169
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1013,
        "y" : 169
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 775,
        "y" : 262
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 775,
        "y" : 262
      }
    },
    "inputs" : [ {
      "id" : 26556,
      "points" : [ {
        "x" : 608,
        "y" : 160
      } ]
    }, {
      "id" : 26558,
      "points" : [ {
        "x" : 699,
        "y" : 170
      } ]
    } ],
    "outputs" : [ {
      "id" : 26559
    } ]
  } ],
  "compartments" : [ {
    "id" : 26596,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1317,
      "y" : 492
    },
    "minX" : 29,
    "maxX" : 2605,
    "minY" : 143,
    "maxY" : 842,
    "prop" : {
      "x" : 29,
      "y" : 143,
      "width" : 2576,
      "height" : 699
    },
    "textPosition" : {
      "x" : 720,
      "y" : 504
    },
    "insets" : {
      "x" : 39,
      "y" : 153,
      "width" : 2556,
      "height" : 679
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 26545, 26546, 26547, 26548, 26551, 26552, 26553, 26555, 26556, 26559, 26563, 26566, 26595, 26568, 26569, 26574, 26544, 26554, 26557, 26564, 26570, 26575, 26576, 26571, 26580, 26578, 26579, 26582, 26583, 26581, 26584, 26585, 26588, 26590, 26589, 26591, 26587, 26572, 26567, 26573, 26586, 26593, 26592, 26594, 26558, 26565, 26577, 26550 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 2605,
  "minY" : 0,
  "maxY" : 867,
  "disease" : false
}