{
  "dbId" : 10730538,
  "stableId" : "R-XTR-1834949",
  "displayName" : "Cytosolic sensors of pathogen-associated DNA ",
  "nodes" : [ {
    "id" : 138370,
    "reactomeId" : 2395973,
    "displayName" : "c-di-GMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 702,
      "y" : 293
    },
    "minX" : 665,
    "maxX" : 864,
    "minY" : 277,
    "maxY" : 319,
    "prop" : {
      "x" : 665,
      "y" : 278,
      "width" : 74,
      "height" : 31
    },
    "textPosition" : {
      "x" : 671,
      "y" : 283
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 734,
          "y" : 283
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 734,
          "y" : 283
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138369,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 742,
          "y" : 298
        },
        "to" : {
          "x" : 864,
          "y" : 319
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138371,
    "reactomeId" : 10690452,
    "displayName" : "STING:STING",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1010,
      "y" : 228
    },
    "minX" : 864,
    "maxX" : 1058,
    "minY" : 211,
    "maxY" : 319,
    "prop" : {
      "x" : 969,
      "y" : 217,
      "width" : 83,
      "height" : 23
    },
    "textPosition" : {
      "x" : 986,
      "y" : 205
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1052,
          "y" : 217
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1052,
          "y" : 217
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138369,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 991,
          "y" : 243
        },
        "to" : {
          "x" : 864,
          "y" : 319
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138373,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138390,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 998,
          "y" : 243
        },
        "to" : {
          "x" : 926,
          "y" : 312
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138374,
    "reactomeId" : 10686032,
    "displayName" : "STING",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 971,
      "y" : 104
    },
    "minX" : 949,
    "maxX" : 999,
    "minY" : 87,
    "maxY" : 153,
    "prop" : {
      "x" : 949,
      "y" : 93,
      "width" : 44,
      "height" : 23
    },
    "textPosition" : {
      "x" : 949,
      "y" : 94
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 993,
          "y" : 93
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 993,
          "y" : 93
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138373,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 953,
            "y" : 141
          },
          "b" : {
            "x" : 965,
            "y" : 153
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 959,
            "y" : 147
          }
        }
      }
    } ]
  }, {
    "id" : 138375,
    "reactomeId" : 10692481,
    "displayName" : "K63polyUb-STING",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1380,
      "y" : 111
    },
    "minX" : 961,
    "maxX" : 1444,
    "minY" : 94,
    "maxY" : 180,
    "prop" : {
      "x" : 1323,
      "y" : 100,
      "width" : 115,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1324,
      "y" : 101
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1438,
          "y" : 100
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1438,
          "y" : 100
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138373,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 1320,
          "y" : 120
        },
        "to" : {
          "x" : 977,
          "y" : 176
        }
      }, {
        "from" : {
          "x" : 977,
          "y" : 176
        },
        "to" : {
          "x" : 961,
          "y" : 176
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 968,
          "y" : 172
        },
        "b" : {
          "x" : 961,
          "y" : 176
        },
        "c" : {
          "x" : 968,
          "y" : 180
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 968,
          "y" : 180
        }
      }
    } ]
  }, {
    "id" : 138372,
    "reactomeId" : 10690459,
    "displayName" : "STING:c-di-GMP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 752,
      "y" : 449
    },
    "minX" : 700,
    "maxX" : 811,
    "minY" : 432,
    "maxY" : 461,
    "prop" : {
      "x" : 700,
      "y" : 438,
      "width" : 105,
      "height" : 23
    },
    "textPosition" : {
      "x" : 702,
      "y" : 440
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 805,
          "y" : 438
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 805,
          "y" : 438
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138369,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138378,
    "reactomeId" : 10692487,
    "displayName" : "phospho-ctnnb1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 845,
      "y" : 1503
    },
    "minX" : 790,
    "maxX" : 906,
    "minY" : 1486,
    "maxY" : 1515,
    "prop" : {
      "x" : 790,
      "y" : 1492,
      "width" : 110,
      "height" : 23
    },
    "textPosition" : {
      "x" : 811,
      "y" : 1486
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 900,
          "y" : 1492
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 900,
          "y" : 1492
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138376,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138377,
    "reactomeId" : 10692489,
    "displayName" : "phospho-ctnnb1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 258,
      "y" : 1091
    },
    "minX" : 203,
    "maxX" : 319,
    "minY" : 1074,
    "maxY" : 1103,
    "prop" : {
      "x" : 203,
      "y" : 1080,
      "width" : 110,
      "height" : 23
    },
    "textPosition" : {
      "x" : 224,
      "y" : 1074
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 313,
          "y" : 1080
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 313,
          "y" : 1080
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138376,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138446,
    "reactomeId" : 10692513,
    "displayName" : "DHX9:CpG:MyD88",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 887,
      "y" : 1363
    },
    "minX" : 829,
    "maxX" : 952,
    "minY" : 1346,
    "maxY" : 1375,
    "prop" : {
      "x" : 829,
      "y" : 1352,
      "width" : 117,
      "height" : 23
    },
    "textPosition" : {
      "x" : 830,
      "y" : 1354
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 946,
          "y" : 1352
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 946,
          "y" : 1352
        }
      }
    },
    "connectors" : [ ]
  }, {
    "id" : 138382,
    "reactomeId" : 10692501,
    "displayName" : "DHX36:CpG",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 289,
      "y" : 1235
    },
    "minX" : 249,
    "maxX" : 335,
    "minY" : 1218,
    "maxY" : 1247,
    "prop" : {
      "x" : 249,
      "y" : 1224,
      "width" : 80,
      "height" : 23
    },
    "textPosition" : {
      "x" : 250,
      "y" : 1226
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 329,
          "y" : 1224
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 329,
          "y" : 1224
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138379,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138380,
    "reactomeId" : 10692499,
    "displayName" : "dhx36",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 132,
      "y" : 1285
    },
    "minX" : 107,
    "maxX" : 191,
    "minY" : 1229,
    "maxY" : 1297,
    "prop" : {
      "x" : 107,
      "y" : 1274,
      "width" : 51,
      "height" : 23
    },
    "textPosition" : {
      "x" : 109,
      "y" : 1275
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 158,
          "y" : 1274
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 158,
          "y" : 1274
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138379,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 144,
          "y" : 1271
        },
        "to" : {
          "x" : 191,
          "y" : 1229
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138381,
    "reactomeId" : 3134861,
    "displayName" : "Unmethylated CpG DNA",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 93,
      "y" : 1221
    },
    "minX" : 33,
    "maxX" : 191,
    "minY" : 1203,
    "maxY" : 1240,
    "prop" : {
      "x" : 33,
      "y" : 1203,
      "width" : 121,
      "height" : 37
    },
    "textPosition" : {
      "x" : 44,
      "y" : 1204
    },
    "connectors" : [ {
      "edgeId" : 138379,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 157,
          "y" : 1225
        },
        "to" : {
          "x" : 191,
          "y" : 1229
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138383,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 157,
          "y" : 1212
        },
        "to" : {
          "x" : 191,
          "y" : 1207
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138387,
    "reactomeId" : 10692509,
    "displayName" : "DHX9/DHX36:CpG",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 344,
      "y" : 1310
    },
    "minX" : 284,
    "maxX" : 404,
    "minY" : 1299,
    "maxY" : 1366,
    "prop" : {
      "x" : 284,
      "y" : 1299,
      "width" : 120,
      "height" : 23
    },
    "textPosition" : {
      "x" : 286,
      "y" : 1300
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 138386,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 352,
          "y" : 1328
        },
        "to" : {
          "x" : 383,
          "y" : 1366
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138384,
    "reactomeId" : 10692505,
    "displayName" : "dhx9",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 130,
      "y" : 1155
    },
    "minX" : 109,
    "maxX" : 191,
    "minY" : 1138,
    "maxY" : 1207,
    "prop" : {
      "x" : 109,
      "y" : 1144,
      "width" : 43,
      "height" : 23
    },
    "textPosition" : {
      "x" : 111,
      "y" : 1145
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 152,
          "y" : 1144
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 152,
          "y" : 1144
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138383,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 143,
          "y" : 1170
        },
        "to" : {
          "x" : 191,
          "y" : 1207
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138385,
    "reactomeId" : 10692507,
    "displayName" : "DHX9:CpG",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 288,
      "y" : 1200
    },
    "minX" : 252,
    "maxX" : 330,
    "minY" : 1183,
    "maxY" : 1212,
    "prop" : {
      "x" : 252,
      "y" : 1189,
      "width" : 72,
      "height" : 23
    },
    "textPosition" : {
      "x" : 253,
      "y" : 1191
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 324,
          "y" : 1189
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 324,
          "y" : 1189
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138383,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138391,
    "reactomeId" : 3244587,
    "displayName" : "c-GMP-AMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 790,
      "y" : 262
    },
    "minX" : 746,
    "maxX" : 926,
    "minY" : 246,
    "maxY" : 312,
    "prop" : {
      "x" : 746,
      "y" : 247,
      "width" : 88,
      "height" : 31
    },
    "textPosition" : {
      "x" : 752,
      "y" : 252
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 829,
          "y" : 252
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 829,
          "y" : 252
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138390,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 832,
          "y" : 281
        },
        "to" : {
          "x" : 926,
          "y" : 312
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138388,
    "reactomeId" : 10664091,
    "displayName" : "myd88",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 297,
      "y" : 1361
    },
    "minX" : 272,
    "maxX" : 383,
    "minY" : 1344,
    "maxY" : 1373,
    "prop" : {
      "x" : 272,
      "y" : 1350,
      "width" : 51,
      "height" : 23
    },
    "textPosition" : {
      "x" : 273,
      "y" : 1351
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 323,
          "y" : 1350
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 323,
          "y" : 1350
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138386,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 326,
          "y" : 1362
        },
        "to" : {
          "x" : 383,
          "y" : 1366
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 348,
            "y" : 1358
          },
          "b" : {
            "x" : 360,
            "y" : 1370
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 354,
            "y" : 1364
          }
        }
      }
    } ]
  }, {
    "id" : 138389,
    "reactomeId" : 10692515,
    "displayName" : "DHX9/DHX36:CpG:MyD88",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 383,
      "y" : 1446
    },
    "minX" : 321,
    "maxX" : 445,
    "minY" : 1428,
    "maxY" : 1465,
    "prop" : {
      "x" : 321,
      "y" : 1428,
      "width" : 124,
      "height" : 37
    },
    "textPosition" : {
      "x" : 323,
      "y" : 1429
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 138386,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138394,
    "reactomeId" : 10690457,
    "displayName" : "STING:STING",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1100,
      "y" : 458
    },
    "minX" : 1059,
    "maxX" : 1172,
    "minY" : 426,
    "maxY" : 470,
    "prop" : {
      "x" : 1059,
      "y" : 447,
      "width" : 83,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1076,
      "y" : 435
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1142,
          "y" : 447
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1142,
          "y" : 447
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138393,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1125,
          "y" : 444
        },
        "to" : {
          "x" : 1172,
          "y" : 426
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138395,
    "reactomeId" : 10670936,
    "displayName" : "stat6",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1147,
      "y" : 383
    },
    "minX" : 1124,
    "maxX" : 1177,
    "minY" : 366,
    "maxY" : 426,
    "prop" : {
      "x" : 1124,
      "y" : 372,
      "width" : 47,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1127,
      "y" : 373
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1171,
          "y" : 372
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1171,
          "y" : 372
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138393,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1153,
          "y" : 398
        },
        "to" : {
          "x" : 1172,
          "y" : 426
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1156,
            "y" : 406
          },
          "b" : {
            "x" : 1168,
            "y" : 418
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1162,
            "y" : 412
          }
        }
      }
    } ]
  }, {
    "id" : 138392,
    "reactomeId" : 10692835,
    "displayName" : "STING:cGAMP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 729,
      "y" : 499
    },
    "minX" : 685,
    "maxX" : 779,
    "minY" : 482,
    "maxY" : 511,
    "prop" : {
      "x" : 685,
      "y" : 488,
      "width" : 88,
      "height" : 23
    },
    "textPosition" : {
      "x" : 704,
      "y" : 476
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 773,
          "y" : 488
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 773,
          "y" : 488
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138390,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138399,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1397,
      "y" : 487
    },
    "minX" : 1346,
    "maxX" : 1418,
    "minY" : 471,
    "maxY" : 503,
    "prop" : {
      "x" : 1377,
      "y" : 472,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1381,
      "y" : 477
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1412,
          "y" : 477
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1412,
          "y" : 477
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138398,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1374,
          "y" : 487
        },
        "to" : {
          "x" : 1346,
          "y" : 487
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1354,
            "y" : 481
          },
          "b" : {
            "x" : 1366,
            "y" : 493
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1360,
            "y" : 487
          }
        }
      }
    } ]
  }, {
    "id" : 138396,
    "reactomeId" : 10693143,
    "displayName" : "TBK1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1092,
      "y" : 407
    },
    "minX" : 1072,
    "maxX" : 1172,
    "minY" : 390,
    "maxY" : 426,
    "prop" : {
      "x" : 1072,
      "y" : 396,
      "width" : 40,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1073,
      "y" : 397
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1112,
          "y" : 396
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1112,
          "y" : 396
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138393,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1115,
          "y" : 411
        },
        "to" : {
          "x" : 1172,
          "y" : 426
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1137,
            "y" : 412
          },
          "b" : {
            "x" : 1149,
            "y" : 424
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1143,
            "y" : 418
          }
        }
      }
    } ]
  }, {
    "id" : 138397,
    "reactomeId" : 10693145,
    "displayName" : "STING:TBK1:STAT6",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1280,
      "y" : 461
    },
    "minX" : 1220,
    "maxX" : 1347,
    "minY" : 444,
    "maxY" : 487,
    "prop" : {
      "x" : 1220,
      "y" : 450,
      "width" : 121,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1220,
      "y" : 452
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1341,
          "y" : 450
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1341,
          "y" : 450
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138393,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138398,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1309,
          "y" : 476
        },
        "to" : {
          "x" : 1346,
          "y" : 487
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138403,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1411,
      "y" : 616
    },
    "minX" : 1354,
    "maxX" : 1432,
    "minY" : 600,
    "maxY" : 632,
    "prop" : {
      "x" : 1391,
      "y" : 601,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1395,
      "y" : 606
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1426,
          "y" : 606
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1426,
          "y" : 606
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138402,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1388,
          "y" : 615
        },
        "to" : {
          "x" : 1354,
          "y" : 614
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1365,
            "y" : 608
          },
          "b" : {
            "x" : 1377,
            "y" : 620
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1371,
            "y" : 614
          }
        }
      }
    } ]
  }, {
    "id" : 138400,
    "reactomeId" : 10693132,
    "displayName" : "STING:p-S172-TBK1:STAT6",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1351,
      "y" : 566
    },
    "minX" : 1301,
    "maxX" : 1407,
    "minY" : 525,
    "maxY" : 636,
    "prop" : {
      "x" : 1301,
      "y" : 548,
      "width" : 100,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1303,
      "y" : 550
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1401,
          "y" : 548
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1401,
          "y" : 548
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138402,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1352,
          "y" : 588
        },
        "to" : {
          "x" : 1354,
          "y" : 614
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138402,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1343,
          "y" : 588
        },
        "to" : {
          "x" : 1330,
          "y" : 620
        }
      }, {
        "from" : {
          "x" : 1330,
          "y" : 620
        },
        "to" : {
          "x" : 1342,
          "y" : 629
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1345,
          "y" : 632
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1345,
          "y" : 632
        }
      }
    }, {
      "edgeId" : 138398,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1349,
          "y" : 545
        },
        "to" : {
          "x" : 1347,
          "y" : 525
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1344,
          "y" : 539
        },
        "b" : {
          "x" : 1349,
          "y" : 545
        },
        "c" : {
          "x" : 1352,
          "y" : 538
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1352,
          "y" : 538
        }
      }
    } ]
  }, {
    "id" : 138401,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1401,
      "y" : 525
    },
    "minX" : 1347,
    "maxX" : 1423,
    "minY" : 509,
    "maxY" : 541,
    "prop" : {
      "x" : 1381,
      "y" : 510,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1385,
      "y" : 515
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1417,
          "y" : 515
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1417,
          "y" : 515
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138398,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1378,
          "y" : 525
        },
        "to" : {
          "x" : 1347,
          "y" : 525
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1356,
            "y" : 519
          },
          "b" : {
            "x" : 1368,
            "y" : 531
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1362,
            "y" : 525
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1371,
          "y" : 529
        },
        "b" : {
          "x" : 1378,
          "y" : 525
        },
        "c" : {
          "x" : 1371,
          "y" : 521
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1371,
          "y" : 521
        }
      }
    } ]
  }, {
    "id" : 138406,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1417,
      "y" : 662
    },
    "minX" : 1356,
    "maxX" : 1439,
    "minY" : 646,
    "maxY" : 678,
    "prop" : {
      "x" : 1397,
      "y" : 647,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1401,
      "y" : 652
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1433,
          "y" : 652
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1433,
          "y" : 652
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138402,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1394,
          "y" : 659
        },
        "to" : {
          "x" : 1356,
          "y" : 655
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1369,
            "y" : 651
          },
          "b" : {
            "x" : 1381,
            "y" : 663
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1375,
            "y" : 657
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1387,
          "y" : 662
        },
        "b" : {
          "x" : 1394,
          "y" : 659
        },
        "c" : {
          "x" : 1388,
          "y" : 654
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1388,
          "y" : 654
        }
      }
    } ]
  }, {
    "id" : 138404,
    "reactomeId" : 10693134,
    "displayName" : "STING:p-S172-TBK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 946,
      "y" : 601
    },
    "minX" : 881,
    "maxX" : 1356,
    "minY" : 556,
    "maxY" : 686,
    "prop" : {
      "x" : 881,
      "y" : 590,
      "width" : 131,
      "height" : 23
    },
    "textPosition" : {
      "x" : 883,
      "y" : 592
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1012,
          "y" : 590
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1012,
          "y" : 590
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138402,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 947,
          "y" : 587
        },
        "to" : {
          "x" : 950,
          "y" : 557
        }
      }, {
        "from" : {
          "x" : 950,
          "y" : 557
        },
        "to" : {
          "x" : 1275,
          "y" : 556
        }
      }, {
        "from" : {
          "x" : 1275,
          "y" : 556
        },
        "to" : {
          "x" : 1326,
          "y" : 686
        }
      }, {
        "from" : {
          "x" : 1326,
          "y" : 686
        },
        "to" : {
          "x" : 1356,
          "y" : 655
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 944,
          "y" : 580
        },
        "b" : {
          "x" : 947,
          "y" : 587
        },
        "c" : {
          "x" : 952,
          "y" : 581
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 952,
          "y" : 581
        }
      }
    } ]
  }, {
    "id" : 138469,
    "reactomeId" : 10730166,
    "displayName" : "DDX58/IFIH1-mediated induction of interferon-alpha/beta",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 111,
      "y" : 1555
    },
    "minX" : 45,
    "maxX" : 177,
    "minY" : 1519,
    "maxY" : 1592,
    "prop" : {
      "x" : 45,
      "y" : 1519,
      "width" : 132,
      "height" : 73
    },
    "textPosition" : {
      "x" : 63,
      "y" : 1513
    },
    "connectors" : [ ]
  }, {
    "id" : 138405,
    "reactomeId" : 10693136,
    "displayName" : "phospho-stat6",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1361,
      "y" : 720
    },
    "minX" : 1312,
    "maxX" : 1417,
    "minY" : 655,
    "maxY" : 750,
    "prop" : {
      "x" : 1312,
      "y" : 709,
      "width" : 99,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1328,
      "y" : 703
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1411,
          "y" : 709
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1411,
          "y" : 709
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138402,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1360,
          "y" : 706
        },
        "to" : {
          "x" : 1356,
          "y" : 655
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1352,
            "y" : 674
          },
          "b" : {
            "x" : 1364,
            "y" : 686
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1358,
            "y" : 680
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1355,
          "y" : 699
        },
        "b" : {
          "x" : 1360,
          "y" : 706
        },
        "c" : {
          "x" : 1363,
          "y" : 699
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1363,
          "y" : 699
        }
      }
    }, {
      "edgeId" : 138407,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1361,
          "y" : 735
        },
        "to" : {
          "x" : 1362,
          "y" : 750
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138410,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1409,
      "y" : 804
    },
    "minX" : 1363,
    "maxX" : 1431,
    "minY" : 788,
    "maxY" : 820,
    "prop" : {
      "x" : 1389,
      "y" : 789,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1393,
      "y" : 794
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1425,
          "y" : 794
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1425,
          "y" : 794
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138407,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1386,
          "y" : 801
        },
        "to" : {
          "x" : 1363,
          "y" : 799
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1379,
          "y" : 804
        },
        "b" : {
          "x" : 1386,
          "y" : 801
        },
        "c" : {
          "x" : 1379,
          "y" : 796
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1379,
          "y" : 796
        }
      }
    } ]
  }, {
    "id" : 138408,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1409,
      "y" : 754
    },
    "minX" : 1362,
    "maxX" : 1430,
    "minY" : 738,
    "maxY" : 770,
    "prop" : {
      "x" : 1389,
      "y" : 739,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1393,
      "y" : 744
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1424,
          "y" : 744
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1424,
          "y" : 744
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138407,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1386,
          "y" : 752
        },
        "to" : {
          "x" : 1362,
          "y" : 750
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138409,
    "reactomeId" : 10693117,
    "displayName" : "phospho-stat6",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1365,
      "y" : 861
    },
    "minX" : 1317,
    "maxX" : 1419,
    "minY" : 799,
    "maxY" : 960,
    "prop" : {
      "x" : 1317,
      "y" : 843,
      "width" : 96,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1331,
      "y" : 844
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1413,
          "y" : 843
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1413,
          "y" : 843
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138407,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1364,
          "y" : 840
        },
        "to" : {
          "x" : 1363,
          "y" : 799
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1360,
          "y" : 833
        },
        "b" : {
          "x" : 1364,
          "y" : 840
        },
        "c" : {
          "x" : 1368,
          "y" : 833
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1368,
          "y" : 833
        }
      }
    }, {
      "edgeId" : 138411,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1359,
            "y" : 948
          },
          "b" : {
            "x" : 1371,
            "y" : 960
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1365,
            "y" : 954
          }
        }
      }
    } ]
  }, {
    "id" : 138414,
    "reactomeId" : 10693123,
    "displayName" : "p-S407,Y641-STAT6 dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1271,
      "y" : 1418
    },
    "minX" : 1223,
    "maxX" : 1325,
    "minY" : 1394,
    "maxY" : 1437,
    "prop" : {
      "x" : 1223,
      "y" : 1400,
      "width" : 96,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1225,
      "y" : 1402
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1319,
          "y" : 1400
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1319,
          "y" : 1400
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138413,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138412,
    "reactomeId" : 10693119,
    "displayName" : "p-S407,Y641-STAT6 dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1314,
      "y" : 1158
    },
    "minX" : 1266,
    "maxX" : 1368,
    "minY" : 1134,
    "maxY" : 1177,
    "prop" : {
      "x" : 1266,
      "y" : 1140,
      "width" : 96,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1268,
      "y" : 1142
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1362,
          "y" : 1140
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1362,
          "y" : 1140
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138411,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138413,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138477,
    "reactomeId" : 10729172,
    "displayName" : "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 510,
      "y" : 637
    },
    "minX" : 414,
    "maxX" : 607,
    "minY" : 595,
    "maxY" : 679,
    "prop" : {
      "x" : 414,
      "y" : 595,
      "width" : 193,
      "height" : 84
    },
    "textPosition" : {
      "x" : 415,
      "y" : 601
    },
    "connectors" : [ ]
  }, {
    "id" : 138418,
    "reactomeId" : 10692569,
    "displayName" : "MRE11:dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 559,
      "y" : 517
    },
    "minX" : 512,
    "maxX" : 612,
    "minY" : 500,
    "maxY" : 529,
    "prop" : {
      "x" : 512,
      "y" : 506,
      "width" : 94,
      "height" : 23
    },
    "textPosition" : {
      "x" : 532,
      "y" : 494
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 606,
          "y" : 506
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 606,
          "y" : 506
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138415,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138416,
    "reactomeId" : 10692567,
    "displayName" : "mre11",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 369,
      "y" : 535
    },
    "minX" : 340,
    "maxX" : 441,
    "minY" : 515,
    "maxY" : 547,
    "prop" : {
      "x" : 340,
      "y" : 524,
      "width" : 58,
      "height" : 23
    },
    "textPosition" : {
      "x" : 345,
      "y" : 525
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 398,
          "y" : 524
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 398,
          "y" : 524
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138415,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 401,
          "y" : 526
        },
        "to" : {
          "x" : 441,
          "y" : 515
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138417,
    "reactomeId" : 874088,
    "displayName" : "Double-stranded DNA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 423,
      "y" : 477
    },
    "minX" : 363,
    "maxX" : 485,
    "minY" : 454,
    "maxY" : 515,
    "prop" : {
      "x" : 363,
      "y" : 455,
      "width" : 121,
      "height" : 45
    },
    "textPosition" : {
      "x" : 365,
      "y" : 460
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 479,
          "y" : 460
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 479,
          "y" : 460
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138415,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 433,
          "y" : 503
        },
        "to" : {
          "x" : 441,
          "y" : 515
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138422,
    "reactomeId" : 10719821,
    "displayName" : "DDX41:c-di-AMP, c-di-GMP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 547,
      "y" : 261
    },
    "minX" : 488,
    "maxX" : 613,
    "minY" : 237,
    "maxY" : 280,
    "prop" : {
      "x" : 488,
      "y" : 243,
      "width" : 119,
      "height" : 37
    },
    "textPosition" : {
      "x" : 491,
      "y" : 245
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 607,
          "y" : 243
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 607,
          "y" : 243
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138419,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138420,
    "reactomeId" : 8982080,
    "displayName" : "c-di-AMP, c-di-GMP",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 212,
      "y" : 261
    },
    "minX" : 147,
    "maxX" : 330,
    "minY" : 250,
    "maxY" : 273,
    "prop" : {
      "x" : 147,
      "y" : 250,
      "width" : 130,
      "height" : 23
    },
    "textPosition" : {
      "x" : 151,
      "y" : 251
    },
    "connectors" : [ {
      "edgeId" : 138419,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 283,
          "y" : 260
        },
        "to" : {
          "x" : 330,
          "y" : 260
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138421,
    "reactomeId" : 10692495,
    "displayName" : "ddx41",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 252,
      "y" : 124
    },
    "minX" : 227,
    "maxX" : 330,
    "minY" : 107,
    "maxY" : 260,
    "prop" : {
      "x" : 227,
      "y" : 113,
      "width" : 51,
      "height" : 23
    },
    "textPosition" : {
      "x" : 229,
      "y" : 114
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 278,
          "y" : 113
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 278,
          "y" : 113
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138419,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 258,
          "y" : 139
        },
        "to" : {
          "x" : 330,
          "y" : 260
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138426,
    "reactomeId" : 10692511,
    "displayName" : "DHX36:CpG:MyD88",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 389,
      "y" : 1508
    },
    "minX" : 327,
    "maxX" : 494,
    "minY" : 1491,
    "maxY" : 1558,
    "prop" : {
      "x" : 327,
      "y" : 1497,
      "width" : 125,
      "height" : 23
    },
    "textPosition" : {
      "x" : 328,
      "y" : 1499
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 452,
          "y" : 1497
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 452,
          "y" : 1497
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138423,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 420,
          "y" : 1523
        },
        "to" : {
          "x" : 490,
          "y" : 1545
        }
      }, {
        "from" : {
          "x" : 490,
          "y" : 1545
        },
        "to" : {
          "x" : 491,
          "y" : 1558
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 486,
          "y" : 1551
        },
        "b" : {
          "x" : 491,
          "y" : 1558
        },
        "c" : {
          "x" : 494,
          "y" : 1551
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 494,
          "y" : 1551
        }
      }
    } ]
  }, {
    "id" : 138424,
    "reactomeId" : 10661167,
    "displayName" : "p-2S-IRF7:p-2S-IRF7",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 377,
      "y" : 1565
    },
    "minX" : 322,
    "maxX" : 438,
    "minY" : 1541,
    "maxY" : 1584,
    "prop" : {
      "x" : 322,
      "y" : 1547,
      "width" : 110,
      "height" : 37
    },
    "textPosition" : {
      "x" : 326,
      "y" : 1549
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 432,
          "y" : 1547
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 432,
          "y" : 1547
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138423,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 138425,
    "reactomeId" : 10662524,
    "displayName" : "2xp-S477,S479-IRF7",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 609,
      "y" : 1567
    },
    "minX" : 554,
    "maxX" : 670,
    "minY" : 1543,
    "maxY" : 1586,
    "prop" : {
      "x" : 554,
      "y" : 1549,
      "width" : 110,
      "height" : 37
    },
    "textPosition" : {
      "x" : 556,
      "y" : 1551
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 664,
          "y" : 1549
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 664,
          "y" : 1549
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138423,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 138402,
    "reactomeId" : 10693139,
    "displayName" : "TBK1 phosphorylates STAT6 at Ser407",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1355,
      "y" : 639
    },
    "minX" : 1349,
    "maxX" : 1361,
    "minY" : 614,
    "maxY" : 655,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1354,
        "y" : 614
      },
      "to" : {
        "x" : 1355,
        "y" : 639
      }
    }, {
      "from" : {
        "x" : 1355,
        "y" : 639
      },
      "to" : {
        "x" : 1356,
        "y" : 655
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1349,
        "y" : 633
      },
      "b" : {
        "x" : 1361,
        "y" : 645
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1355,
        "y" : 639
      }
    },
    "inputs" : [ {
      "id" : 138403,
      "points" : [ {
        "x" : 1388,
        "y" : 615
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 138400,
      "points" : [ {
        "x" : 1352,
        "y" : 588
      } ]
    } ],
    "outputs" : [ {
      "id" : 138404,
      "points" : [ {
        "x" : 947,
        "y" : 587
      }, {
        "x" : 950,
        "y" : 557
      }, {
        "x" : 1275,
        "y" : 556
      }, {
        "x" : 1326,
        "y" : 686
      } ]
    }, {
      "id" : 138405,
      "points" : [ {
        "x" : 1360,
        "y" : 706
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 138406,
      "points" : [ {
        "x" : 1394,
        "y" : 659
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 138400,
      "points" : [ {
        "x" : 1343,
        "y" : 588
      }, {
        "x" : 1330,
        "y" : 620
      } ]
    } ]
  }, {
    "id" : 138369,
    "reactomeId" : 10690461,
    "displayName" : "STING binds c-di-GMP",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 864,
      "y" : 341
    },
    "minX" : 763,
    "maxX" : 870,
    "minY" : 319,
    "maxY" : 435,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 864,
        "y" : 319
      },
      "to" : {
        "x" : 864,
        "y" : 341
      }
    }, {
      "from" : {
        "x" : 864,
        "y" : 341
      },
      "to" : {
        "x" : 763,
        "y" : 435
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 765,
        "y" : 427
      },
      "b" : {
        "x" : 763,
        "y" : 435
      },
      "c" : {
        "x" : 771,
        "y" : 433
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 771,
        "y" : 433
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 858,
        "y" : 335
      },
      "b" : {
        "x" : 870,
        "y" : 347
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 864,
        "y" : 341
      }
    },
    "inputs" : [ {
      "id" : 138370,
      "points" : [ {
        "x" : 742,
        "y" : 298
      } ]
    }, {
      "id" : 138371,
      "points" : [ {
        "x" : 991,
        "y" : 243
      } ]
    } ],
    "outputs" : [ {
      "id" : 138372
    } ]
  }, {
    "id" : 138407,
    "reactomeId" : 10693149,
    "displayName" : "p-S407-STAT6 is phosphorylated at Tyr641",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1362,
      "y" : 776
    },
    "minX" : 1356,
    "maxX" : 1368,
    "minY" : 750,
    "maxY" : 799,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1362,
        "y" : 750
      },
      "to" : {
        "x" : 1362,
        "y" : 776
      }
    }, {
      "from" : {
        "x" : 1362,
        "y" : 776
      },
      "to" : {
        "x" : 1363,
        "y" : 799
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1356,
        "y" : 770
      },
      "b" : {
        "x" : 1368,
        "y" : 782
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1362,
        "y" : 776
      }
    },
    "inputs" : [ {
      "id" : 138408,
      "points" : [ {
        "x" : 1386,
        "y" : 752
      } ]
    }, {
      "id" : 138405,
      "points" : [ {
        "x" : 1361,
        "y" : 735
      } ]
    } ],
    "outputs" : [ {
      "id" : 138409,
      "points" : [ {
        "x" : 1364,
        "y" : 840
      } ]
    }, {
      "id" : 138410,
      "points" : [ {
        "x" : 1386,
        "y" : 801
      } ]
    } ]
  }, {
    "id" : 138373,
    "reactomeId" : 10692483,
    "displayName" : "STING dimerization",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 952,
      "y" : 176
    },
    "minX" : 946,
    "maxX" : 997,
    "minY" : 119,
    "maxY" : 214,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 967,
        "y" : 119
      },
      "to" : {
        "x" : 952,
        "y" : 176
      }
    }, {
      "from" : {
        "x" : 952,
        "y" : 176
      },
      "to" : {
        "x" : 997,
        "y" : 214
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 989,
        "y" : 213
      },
      "b" : {
        "x" : 997,
        "y" : 214
      },
      "c" : {
        "x" : 994,
        "y" : 206
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 994,
        "y" : 206
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 952,
        "y" : 176
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 952,
        "y" : 176
      }
    },
    "inputs" : [ {
      "id" : 138374,
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 138371
    } ],
    "activators" : [ {
      "id" : 138375,
      "points" : [ {
        "x" : 1320,
        "y" : 120
      }, {
        "x" : 977,
        "y" : 176
      } ]
    } ]
  }, {
    "id" : 138379,
    "reactomeId" : 10692521,
    "displayName" : "DHX36 binds DNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 222,
      "y" : 1229
    },
    "minX" : 191,
    "maxX" : 246,
    "minY" : 1223,
    "maxY" : 1235,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 191,
        "y" : 1229
      },
      "to" : {
        "x" : 222,
        "y" : 1229
      }
    }, {
      "from" : {
        "x" : 222,
        "y" : 1229
      },
      "to" : {
        "x" : 246,
        "y" : 1231
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 239,
        "y" : 1234
      },
      "b" : {
        "x" : 246,
        "y" : 1231
      },
      "c" : {
        "x" : 239,
        "y" : 1226
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 239,
        "y" : 1226
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 222,
        "y" : 1229
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 222,
        "y" : 1229
      }
    },
    "inputs" : [ {
      "id" : 138380,
      "points" : [ {
        "x" : 144,
        "y" : 1271
      } ]
    }, {
      "id" : 138381,
      "points" : [ {
        "x" : 157,
        "y" : 1225
      } ]
    } ],
    "outputs" : [ {
      "id" : 138382
    } ]
  }, {
    "id" : 138411,
    "reactomeId" : 10693141,
    "displayName" : "p-S407,Y641-STAT6 is dimerized",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1365,
      "y" : 1026
    },
    "minX" : 1321,
    "maxX" : 1371,
    "minY" : 883,
    "maxY" : 1137,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1365,
        "y" : 883
      },
      "to" : {
        "x" : 1365,
        "y" : 1026
      }
    }, {
      "from" : {
        "x" : 1365,
        "y" : 1026
      },
      "to" : {
        "x" : 1321,
        "y" : 1137
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1320,
        "y" : 1129
      },
      "b" : {
        "x" : 1321,
        "y" : 1137
      },
      "c" : {
        "x" : 1327,
        "y" : 1132
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1327,
        "y" : 1132
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1365,
        "y" : 1026
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1365,
        "y" : 1026
      }
    },
    "inputs" : [ {
      "id" : 138409,
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 138412
    } ]
  }, {
    "id" : 138376,
    "reactomeId" : 10692491,
    "displayName" : "Beta-catenin migrates to the nucleus",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 487,
      "y" : 1366
    },
    "minX" : 267,
    "maxX" : 814,
    "minY" : 1106,
    "maxY" : 1489,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 267,
        "y" : 1106
      },
      "to" : {
        "x" : 487,
        "y" : 1366
      }
    }, {
      "from" : {
        "x" : 487,
        "y" : 1366
      },
      "to" : {
        "x" : 814,
        "y" : 1489
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 806,
        "y" : 1490
      },
      "b" : {
        "x" : 814,
        "y" : 1489
      },
      "c" : {
        "x" : 809,
        "y" : 1483
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 809,
        "y" : 1483
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 481,
        "y" : 1360
      },
      "b" : {
        "x" : 493,
        "y" : 1372
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 487,
        "y" : 1366
      }
    },
    "inputs" : [ {
      "id" : 138377
    } ],
    "outputs" : [ {
      "id" : 138378
    } ]
  }, {
    "id" : 138383,
    "reactomeId" : 10692519,
    "displayName" : "DHX9 binds DNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 222,
      "y" : 1207
    },
    "minX" : 191,
    "maxX" : 249,
    "minY" : 1201,
    "maxY" : 1213,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 191,
        "y" : 1207
      },
      "to" : {
        "x" : 222,
        "y" : 1207
      }
    }, {
      "from" : {
        "x" : 222,
        "y" : 1207
      },
      "to" : {
        "x" : 249,
        "y" : 1203
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 243,
        "y" : 1208
      },
      "b" : {
        "x" : 249,
        "y" : 1203
      },
      "c" : {
        "x" : 242,
        "y" : 1200
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 242,
        "y" : 1200
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 222,
        "y" : 1207
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 222,
        "y" : 1207
      }
    },
    "inputs" : [ {
      "id" : 138384,
      "points" : [ {
        "x" : 143,
        "y" : 1170
      } ]
    }, {
      "id" : 138381,
      "points" : [ {
        "x" : 157,
        "y" : 1212
      } ]
    } ],
    "outputs" : [ {
      "id" : 138385
    } ]
  }, {
    "id" : 138415,
    "reactomeId" : 10692571,
    "displayName" : "MRE11 binds cytosolic DNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 468,
      "y" : 516
    },
    "minX" : 441,
    "maxX" : 509,
    "minY" : 510,
    "maxY" : 522,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 441,
        "y" : 515
      },
      "to" : {
        "x" : 468,
        "y" : 516
      }
    }, {
      "from" : {
        "x" : 468,
        "y" : 516
      },
      "to" : {
        "x" : 509,
        "y" : 516
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 502,
        "y" : 520
      },
      "b" : {
        "x" : 509,
        "y" : 516
      },
      "c" : {
        "x" : 502,
        "y" : 512
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 502,
        "y" : 512
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 468,
        "y" : 516
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 468,
        "y" : 516
      }
    },
    "inputs" : [ {
      "id" : 138416,
      "points" : [ {
        "x" : 401,
        "y" : 526
      } ]
    }, {
      "id" : 138417,
      "points" : [ {
        "x" : 433,
        "y" : 503
      } ]
    } ],
    "outputs" : [ {
      "id" : 138418
    } ]
  }, {
    "id" : 138413,
    "reactomeId" : 10693125,
    "displayName" : "p-S407,Y641-STAT6 dimer migrates to the nucleus",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1317,
      "y" : 1362
    },
    "minX" : 1286,
    "maxX" : 1323,
    "minY" : 1180,
    "maxY" : 1397,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1314,
        "y" : 1180
      },
      "to" : {
        "x" : 1317,
        "y" : 1362
      }
    }, {
      "from" : {
        "x" : 1317,
        "y" : 1362
      },
      "to" : {
        "x" : 1286,
        "y" : 1397
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1288,
        "y" : 1389
      },
      "b" : {
        "x" : 1286,
        "y" : 1397
      },
      "c" : {
        "x" : 1294,
        "y" : 1394
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1294,
        "y" : 1394
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1311,
        "y" : 1356
      },
      "b" : {
        "x" : 1323,
        "y" : 1368
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1317,
        "y" : 1362
      }
    },
    "inputs" : [ {
      "id" : 138412
    } ],
    "outputs" : [ {
      "id" : 138414
    } ]
  }, {
    "id" : 138386,
    "reactomeId" : 10692517,
    "displayName" : "DHX36 or DHX9 binds MyD88",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 383,
      "y" : 1399
    },
    "minX" : 377,
    "maxX" : 389,
    "minY" : 1366,
    "maxY" : 1422,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 383,
        "y" : 1366
      },
      "to" : {
        "x" : 383,
        "y" : 1399
      }
    }, {
      "from" : {
        "x" : 383,
        "y" : 1399
      },
      "to" : {
        "x" : 383,
        "y" : 1422
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 379,
        "y" : 1415
      },
      "b" : {
        "x" : 383,
        "y" : 1422
      },
      "c" : {
        "x" : 387,
        "y" : 1415
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 387,
        "y" : 1415
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 377,
        "y" : 1393
      },
      "b" : {
        "x" : 389,
        "y" : 1405
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 383,
        "y" : 1399
      }
    },
    "inputs" : [ {
      "id" : 138387,
      "points" : [ {
        "x" : 352,
        "y" : 1328
      } ]
    }, {
      "id" : 138388,
      "points" : [ {
        "x" : 326,
        "y" : 1362
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 138389
    } ]
  }, {
    "id" : 138419,
    "reactomeId" : 10719823,
    "displayName" : "DDX41 binds bacterial c-di-AMP, c-di-GMP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 453,
      "y" : 260
    },
    "minX" : 330,
    "maxX" : 485,
    "minY" : 254,
    "maxY" : 266,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 330,
        "y" : 260
      },
      "to" : {
        "x" : 453,
        "y" : 260
      }
    }, {
      "from" : {
        "x" : 453,
        "y" : 260
      },
      "to" : {
        "x" : 485,
        "y" : 260
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 478,
        "y" : 264
      },
      "b" : {
        "x" : 485,
        "y" : 260
      },
      "c" : {
        "x" : 478,
        "y" : 256
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 478,
        "y" : 256
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 453,
        "y" : 260
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 453,
        "y" : 260
      }
    },
    "inputs" : [ {
      "id" : 138420,
      "points" : [ {
        "x" : 283,
        "y" : 260
      } ]
    }, {
      "id" : 138421,
      "points" : [ {
        "x" : 258,
        "y" : 139
      } ]
    } ],
    "outputs" : [ {
      "id" : 138422
    } ]
  }, {
    "id" : 138390,
    "reactomeId" : 10692837,
    "displayName" : "STING binds cyclic GMP-AMP",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 927,
      "y" : 347
    },
    "minX" : 763,
    "maxX" : 933,
    "minY" : 312,
    "maxY" : 485,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 926,
        "y" : 312
      },
      "to" : {
        "x" : 927,
        "y" : 347
      }
    }, {
      "from" : {
        "x" : 927,
        "y" : 347
      },
      "to" : {
        "x" : 797,
        "y" : 476
      }
    }, {
      "from" : {
        "x" : 797,
        "y" : 476
      },
      "to" : {
        "x" : 763,
        "y" : 485
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 769,
        "y" : 479
      },
      "b" : {
        "x" : 763,
        "y" : 485
      },
      "c" : {
        "x" : 771,
        "y" : 487
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 771,
        "y" : 487
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 921,
        "y" : 341
      },
      "b" : {
        "x" : 933,
        "y" : 353
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 927,
        "y" : 347
      }
    },
    "inputs" : [ {
      "id" : 138391,
      "points" : [ {
        "x" : 832,
        "y" : 281
      } ]
    }, {
      "id" : 138371,
      "points" : [ {
        "x" : 998,
        "y" : 243
      } ]
    } ],
    "outputs" : [ {
      "id" : 138392
    } ]
  }, {
    "id" : 138423,
    "reactomeId" : 10721115,
    "displayName" : "p-IRF7:p-IRF7 translocates to the nucleus",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 491,
      "y" : 1567
    },
    "minX" : 435,
    "maxX" : 551,
    "minY" : 1561,
    "maxY" : 1573,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 435,
        "y" : 1565
      },
      "to" : {
        "x" : 491,
        "y" : 1567
      }
    }, {
      "from" : {
        "x" : 491,
        "y" : 1567
      },
      "to" : {
        "x" : 551,
        "y" : 1567
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 544,
        "y" : 1571
      },
      "b" : {
        "x" : 551,
        "y" : 1567
      },
      "c" : {
        "x" : 544,
        "y" : 1563
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 544,
        "y" : 1563
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 485,
        "y" : 1561
      },
      "b" : {
        "x" : 497,
        "y" : 1573
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 491,
        "y" : 1567
      }
    },
    "inputs" : [ {
      "id" : 138424
    } ],
    "outputs" : [ {
      "id" : 138425
    } ],
    "activators" : [ {
      "id" : 138426,
      "points" : [ {
        "x" : 420,
        "y" : 1523
      }, {
        "x" : 490,
        "y" : 1545
      } ]
    } ]
  }, {
    "id" : 138393,
    "reactomeId" : 10693147,
    "displayName" : "STING recruits TBK1 and STAT6",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1196,
      "y" : 425
    },
    "minX" : 1172,
    "maxX" : 1253,
    "minY" : 419,
    "maxY" : 447,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1172,
        "y" : 426
      },
      "to" : {
        "x" : 1196,
        "y" : 425
      }
    }, {
      "from" : {
        "x" : 1196,
        "y" : 425
      },
      "to" : {
        "x" : 1253,
        "y" : 447
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1245,
        "y" : 448
      },
      "b" : {
        "x" : 1253,
        "y" : 447
      },
      "c" : {
        "x" : 1248,
        "y" : 441
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1248,
        "y" : 441
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1196,
        "y" : 425
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1196,
        "y" : 425
      }
    },
    "inputs" : [ {
      "id" : 138394,
      "points" : [ {
        "x" : 1125,
        "y" : 444
      } ]
    }, {
      "id" : 138395,
      "points" : [ {
        "x" : 1153,
        "y" : 398
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 138396,
      "points" : [ {
        "x" : 1115,
        "y" : 411
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 138397
    } ]
  }, {
    "id" : 138398,
    "reactomeId" : 10693151,
    "displayName" : "TBK1 is phosphorylated within STING:TBK1:STAT6 complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1347,
      "y" : 507
    },
    "minX" : 1341,
    "maxX" : 1353,
    "minY" : 487,
    "maxY" : 525,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1346,
        "y" : 487
      },
      "to" : {
        "x" : 1347,
        "y" : 507
      }
    }, {
      "from" : {
        "x" : 1347,
        "y" : 507
      },
      "to" : {
        "x" : 1347,
        "y" : 525
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1341,
        "y" : 501
      },
      "b" : {
        "x" : 1353,
        "y" : 513
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1347,
        "y" : 507
      }
    },
    "inputs" : [ {
      "id" : 138397,
      "points" : [ {
        "x" : 1309,
        "y" : 476
      } ]
    }, {
      "id" : 138399,
      "points" : [ {
        "x" : 1374,
        "y" : 487
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 138400,
      "points" : [ {
        "x" : 1349,
        "y" : 545
      } ]
    }, {
      "id" : 138401,
      "points" : [ {
        "x" : 1378,
        "y" : 525
      } ],
      "stoichiometry" : 2
    } ]
  } ],
  "compartments" : [ {
    "id" : 138439,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 944,
      "y" : 1493
    },
    "minX" : 507,
    "maxX" : 1381,
    "minY" : 1384,
    "maxY" : 1603,
    "prop" : {
      "x" : 507,
      "y" : 1384,
      "width" : 874,
      "height" : 219
    },
    "textPosition" : {
      "x" : 832,
      "y" : 1558
    },
    "insets" : {
      "x" : 517,
      "y" : 1394,
      "width" : 854,
      "height" : 199
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 138378, 138425, 138414 ]
  }, {
    "id" : 138458,
    "reactomeId" : 437050,
    "displayName" : "cytoplasmic vesicle lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1037,
      "y" : 531
    },
    "minX" : 729,
    "maxX" : 1345,
    "minY" : 451,
    "maxY" : 611,
    "prop" : {
      "x" : 729,
      "y" : 451,
      "width" : 616,
      "height" : 160
    },
    "textPosition" : {
      "x" : 928,
      "y" : 497
    },
    "insets" : {
      "x" : 739,
      "y" : 461,
      "width" : 596,
      "height" : 140
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 138404, 138462, 138397, 138394, 138392, 138372, 138400, 138392, 138372 ]
  }, {
    "id" : 138475,
    "reactomeId" : 17940,
    "displayName" : "endosome",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 643,
      "y" : 1323
    },
    "minX" : 558,
    "maxX" : 728,
    "minY" : 1293,
    "maxY" : 1354,
    "prop" : {
      "x" : 558,
      "y" : 1293,
      "width" : 170,
      "height" : 61
    },
    "textPosition" : {
      "x" : 578,
      "y" : 1311
    },
    "insets" : {
      "x" : 568,
      "y" : 1303,
      "width" : 150,
      "height" : 41
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    }
  }, {
    "id" : 138427,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 775,
      "y" : 809
    },
    "minX" : 0,
    "maxX" : 1550,
    "minY" : 0,
    "maxY" : 1618,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 1550,
      "height" : 1618
    },
    "textPosition" : {
      "x" : 177,
      "y" : 1308
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 1530,
      "height" : 1598
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 138439, 138369, 138446, 138421, 138377, 138379, 138380, 138381, 138382, 138383, 138384, 138385, 138386, 138387, 138478, 138479, 138389, 138480, 138424, 138426, 138481, 138390, 138418, 138456, 138370, 138391, 138392, 138392, 138372, 138392, 138372, 138392, 138372, 138392, 138372, 138372, 138396, 138395, 138458, 138393, 138372, 138392, 138399, 138398, 138401, 138402, 138403, 138405, 138406, 138409, 138410, 138408, 138407, 138411, 138412, 138415, 138416, 138469, 138482, 138417, 138419, 138420, 138422, 138413, 138376, 138475, 138423, 138373, 138388, 138477, 138483 ]
  }, {
    "id" : 138456,
    "reactomeId" : 70260,
    "displayName" : "endoplasmic reticulum",
    "schemaClass" : "GO_CellularComponent",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1187,
      "y" : 160
    },
    "minX" : 970,
    "maxX" : 1404,
    "minY" : 95,
    "maxY" : 226,
    "prop" : {
      "x" : 970,
      "y" : 95,
      "width" : 434,
      "height" : 131
    },
    "textPosition" : {
      "x" : 1138,
      "y" : 179
    },
    "insets" : {
      "x" : 980,
      "y" : 105,
      "width" : 414,
      "height" : 111
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 138371, 138374, 138375 ]
  } ],
  "notes" : [ {
    "id" : 138462,
    "displayName" : "(perinuclear vesicle)",
    "renderableClass" : "Note",
    "position" : {
      "x" : 1085,
      "y" : 533
    },
    "minX" : 1001,
    "maxX" : 1169,
    "minY" : 524,
    "maxY" : 542,
    "prop" : {
      "x" : 1001,
      "y" : 524,
      "width" : 168,
      "height" : 18
    },
    "textPosition" : {
      "x" : 1017,
      "y" : 523
    }
  } ],
  "links" : [ {
    "id" : 138480,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 797,
      "y" : 1359
    },
    "minX" : 451,
    "maxX" : 826,
    "minY" : 1353,
    "maxY" : 1432,
    "segments" : [ {
      "from" : {
        "x" : 826,
        "y" : 1360
      },
      "to" : {
        "x" : 797,
        "y" : 1359
      }
    }, {
      "from" : {
        "x" : 797,
        "y" : 1359
      },
      "to" : {
        "x" : 451,
        "y" : 1432
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 791,
        "y" : 1353
      },
      "b" : {
        "x" : 803,
        "y" : 1365
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 797,
        "y" : 1359
      }
    },
    "inputs" : [ {
      "id" : 138446
    } ],
    "outputs" : [ {
      "id" : 138389
    } ]
  }, {
    "id" : 138481,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 385,
      "y" : 1482
    },
    "minX" : 379,
    "maxX" : 391,
    "minY" : 1471,
    "maxY" : 1494,
    "segments" : [ {
      "from" : {
        "x" : 387,
        "y" : 1494
      },
      "to" : {
        "x" : 384,
        "y" : 1471
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 379,
        "y" : 1476
      },
      "b" : {
        "x" : 391,
        "y" : 1488
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 385,
        "y" : 1482
      }
    },
    "inputs" : [ {
      "id" : 138426
    } ],
    "outputs" : [ {
      "id" : 138389
    } ]
  }, {
    "id" : 138478,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 336,
      "y" : 1213
    },
    "minX" : 327,
    "maxX" : 343,
    "minY" : 1207,
    "maxY" : 1293,
    "segments" : [ {
      "from" : {
        "x" : 327,
        "y" : 1209
      },
      "to" : {
        "x" : 336,
        "y" : 1213
      }
    }, {
      "from" : {
        "x" : 336,
        "y" : 1213
      },
      "to" : {
        "x" : 343,
        "y" : 1293
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 330,
        "y" : 1207
      },
      "b" : {
        "x" : 342,
        "y" : 1219
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 336,
        "y" : 1213
      }
    },
    "inputs" : [ {
      "id" : 138385
    } ],
    "outputs" : [ {
      "id" : 138387
    } ]
  }, {
    "id" : 138479,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 316,
      "y" : 1271
    },
    "minX" : 298,
    "maxX" : 335,
    "minY" : 1250,
    "maxY" : 1293,
    "segments" : [ {
      "from" : {
        "x" : 298,
        "y" : 1250
      },
      "to" : {
        "x" : 335,
        "y" : 1293
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 310,
        "y" : 1265
      },
      "b" : {
        "x" : 322,
        "y" : 1277
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 316,
        "y" : 1271
      }
    },
    "inputs" : [ {
      "id" : 138382
    } ],
    "outputs" : [ {
      "id" : 138387
    } ]
  } ],
  "shadows" : [ {
    "id" : 138482,
    "reactomeId" : 10730536,
    "displayName" : "STING mediated induction of host immune responses",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 792,
      "y" : 765
    },
    "minX" : 137,
    "maxX" : 1448,
    "minY" : 83,
    "maxY" : 1447,
    "prop" : {
      "x" : 137,
      "y" : 83,
      "width" : 1311,
      "height" : 987
    },
    "points" : [ {
      "x" : 137,
      "y" : 83
    }, {
      "x" : 1448,
      "y" : 83
    }, {
      "x" : 1448,
      "y" : 1447
    }, {
      "x" : 137,
      "y" : 1447
    } ],
    "colour" : "#4684ee"
  }, {
    "id" : 138483,
    "reactomeId" : 10730618,
    "displayName" : "LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 551,
      "y" : 1297
    },
    "minX" : 193,
    "maxX" : 910,
    "minY" : 1070,
    "maxY" : 1525,
    "prop" : {
      "x" : 674,
      "y" : 1447,
      "width" : 236,
      "height" : 78
    },
    "points" : [ {
      "x" : 193,
      "y" : 1070
    }, {
      "x" : 910,
      "y" : 1070
    }, {
      "x" : 910,
      "y" : 1525
    }, {
      "x" : 193,
      "y" : 1525
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 138484,
    "reactomeId" : 10730620,
    "displayName" : "DEx/H-box helicases activate type I IFN and inflammatory cytokines production ",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 348,
      "y" : 1365
    },
    "minX" : 23,
    "maxX" : 674,
    "minY" : 1134,
    "maxY" : 1596,
    "prop" : {
      "x" : 23,
      "y" : 1525,
      "width" : 651,
      "height" : 71
    },
    "points" : [ {
      "x" : 23,
      "y" : 1134
    }, {
      "x" : 674,
      "y" : 1134
    }, {
      "x" : 674,
      "y" : 1596
    }, {
      "x" : 23,
      "y" : 1596
    } ],
    "colour" : "#008000"
  } ],
  "minX" : 0,
  "maxX" : 1550,
  "minY" : 0,
  "maxY" : 1618,
  "disease" : false
}