{
  "dbId" : 10729116,
  "stableId" : "R-XTR-166658",
  "displayName" : "Complement cascade",
  "nodes" : [ {
    "id" : 81991,
    "reactomeId" : 10660930,
    "displayName" : "Cell surface:C4b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1804,
      "y" : 236
    },
    "minX" : 1752,
    "maxX" : 1862,
    "minY" : 198,
    "maxY" : 248,
    "prop" : {
      "x" : 1752,
      "y" : 225,
      "width" : 104,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1761,
      "y" : 213
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1856,
          "y" : 225
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1856,
          "y" : 225
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 81990,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1814,
          "y" : 222
        },
        "to" : {
          "x" : 1838,
          "y" : 198
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82033,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 81993,
    "reactomeId" : 10660932,
    "displayName" : "Cell surface:C4b:C2a",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1912,
      "y" : 236
    },
    "minX" : 1847,
    "maxX" : 2035,
    "minY" : 199,
    "maxY" : 248,
    "prop" : {
      "x" : 1847,
      "y" : 225,
      "width" : 131,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1856,
      "y" : 213
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1978,
          "y" : 225
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1978,
          "y" : 225
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 81990,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82021,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1950,
          "y" : 222
        },
        "to" : {
          "x" : 2035,
          "y" : 199
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 81992,
    "reactomeId" : 10660910,
    "displayName" : "c2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1764,
      "y" : 17
    },
    "minX" : 1748,
    "maxX" : 1838,
    "minY" : 0,
    "maxY" : 198,
    "prop" : {
      "x" : 1748,
      "y" : 6,
      "width" : 32,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1752,
      "y" : 7
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1780,
          "y" : 6
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1780,
          "y" : 6
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 81990,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1768,
          "y" : 32
        },
        "to" : {
          "x" : 1838,
          "y" : 198
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 81995,
    "reactomeId" : 10660954,
    "displayName" : "Complement factor 3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 558,
      "y" : 1238
    },
    "minX" : 493,
    "maxX" : 2039,
    "minY" : 1169,
    "maxY" : 1426,
    "prop" : {
      "x" : 493,
      "y" : 1227,
      "width" : 131,
      "height" : 23
    },
    "textPosition" : {
      "x" : 493,
      "y" : 1215
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 624,
          "y" : 1227
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 624,
          "y" : 1227
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82118,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 556,
          "y" : 1253
        },
        "to" : {
          "x" : 537,
          "y" : 1420
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 81994,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 580,
          "y" : 1253
        },
        "to" : {
          "x" : 799,
          "y" : 1361
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82009,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 562,
          "y" : 1253
        },
        "to" : {
          "x" : 638,
          "y" : 1426
        }
      }, {
        "from" : {
          "x" : 638,
          "y" : 1426
        },
        "to" : {
          "x" : 2018,
          "y" : 1420
        }
      }, {
        "from" : {
          "x" : 2018,
          "y" : 1420
        },
        "to" : {
          "x" : 2039,
          "y" : 1169
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82012,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82016,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 81997,
    "reactomeId" : 10660978,
    "displayName" : "C3(H2O)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1224,
      "y" : 1361
    },
    "minX" : 1195,
    "maxX" : 1282,
    "minY" : 1274,
    "maxY" : 1373,
    "prop" : {
      "x" : 1195,
      "y" : 1350,
      "width" : 59,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1202,
      "y" : 1338
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1254,
          "y" : 1350
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1254,
          "y" : 1350
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 81994,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 81998,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1231,
          "y" : 1347
        },
        "to" : {
          "x" : 1282,
          "y" : 1274
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 81996,
    "reactomeId" : 109276,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 741,
      "y" : 1383
    },
    "minX" : 720,
    "maxX" : 799,
    "minY" : 1361,
    "maxY" : 1399,
    "prop" : {
      "x" : 720,
      "y" : 1368,
      "width" : 43,
      "height" : 31
    },
    "textPosition" : {
      "x" : 724,
      "y" : 1373
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 758,
          "y" : 1373
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 758,
          "y" : 1373
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 81994,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 766,
          "y" : 1374
        },
        "to" : {
          "x" : 799,
          "y" : 1361
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 81999,
    "reactomeId" : 10661790,
    "displayName" : "cfb",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1216,
      "y" : 1204
    },
    "minX" : 1174,
    "maxX" : 1290,
    "minY" : 1176,
    "maxY" : 1274,
    "prop" : {
      "x" : 1174,
      "y" : 1193,
      "width" : 85,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1203,
      "y" : 1194
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1259,
          "y" : 1193
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1259,
          "y" : 1193
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 81998,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1226,
          "y" : 1219
        },
        "to" : {
          "x" : 1282,
          "y" : 1274
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82017,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1246,
          "y" : 1190
        },
        "to" : {
          "x" : 1290,
          "y" : 1176
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82000,
    "reactomeId" : 10661792,
    "displayName" : "C3(H2O):CFB",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1402,
      "y" : 1274
    },
    "minX" : 1360,
    "maxX" : 1450,
    "minY" : 1257,
    "maxY" : 1286,
    "prop" : {
      "x" : 1360,
      "y" : 1263,
      "width" : 84,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1370,
      "y" : 1251
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1444,
          "y" : 1263
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1444,
          "y" : 1263
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 81998,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82001,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82003,
    "reactomeId" : 10660984,
    "displayName" : "C3(H2O):Bb",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1651,
      "y" : 1308
    },
    "minX" : 685,
    "maxX" : 1696,
    "minY" : 1255,
    "maxY" : 1320,
    "prop" : {
      "x" : 1612,
      "y" : 1297,
      "width" : 78,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1619,
      "y" : 1285
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1690,
          "y" : 1297
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1690,
          "y" : 1297
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82001,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1622,
          "y" : 1294
        },
        "to" : {
          "x" : 1569,
          "y" : 1275
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1614,
          "y" : 1295
        },
        "b" : {
          "x" : 1622,
          "y" : 1294
        },
        "c" : {
          "x" : 1617,
          "y" : 1288
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1617,
          "y" : 1288
        }
      }
    }, {
      "edgeId" : 82016,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1609,
          "y" : 1307
        },
        "to" : {
          "x" : 690,
          "y" : 1290
        }
      }, {
        "from" : {
          "x" : 690,
          "y" : 1290
        },
        "to" : {
          "x" : 689,
          "y" : 1263
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 689,
          "y" : 1259
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 689,
          "y" : 1259
        }
      }
    } ]
  }, {
    "id" : 82002,
    "reactomeId" : 10661796,
    "displayName" : "cfb",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1653,
      "y" : 1234
    },
    "minX" : 1569,
    "maxX" : 1702,
    "minY" : 1178,
    "maxY" : 1275,
    "prop" : {
      "x" : 1611,
      "y" : 1223,
      "width" : 85,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1640,
      "y" : 1224
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1696,
          "y" : 1223
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1696,
          "y" : 1223
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82001,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1629,
          "y" : 1249
        },
        "to" : {
          "x" : 1569,
          "y" : 1275
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1624,
          "y" : 1255
        },
        "b" : {
          "x" : 1629,
          "y" : 1249
        },
        "c" : {
          "x" : 1621,
          "y" : 1248
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1621,
          "y" : 1248
        }
      }
    }, {
      "edgeId" : 82020,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1644,
          "y" : 1220
        },
        "to" : {
          "x" : 1612,
          "y" : 1178
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1637,
          "y" : 1217
        },
        "b" : {
          "x" : 1644,
          "y" : 1220
        },
        "c" : {
          "x" : 1643,
          "y" : 1212
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1643,
          "y" : 1212
        }
      }
    } ]
  }, {
    "id" : 82004,
    "reactomeId" : 10661806,
    "displayName" : "Complement factor D",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1515,
      "y" : 1210
    },
    "minX" : 1454,
    "maxX" : 1577,
    "minY" : 1170,
    "maxY" : 1266,
    "prop" : {
      "x" : 1454,
      "y" : 1192,
      "width" : 123,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1470,
      "y" : 1193
    },
    "connectors" : [ {
      "edgeId" : 82001,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1514,
          "y" : 1235
        },
        "to" : {
          "x" : 1513,
          "y" : 1258
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1513,
          "y" : 1262
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1513,
          "y" : 1262
        }
      }
    }, {
      "edgeId" : 82020,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1518,
          "y" : 1186
        },
        "to" : {
          "x" : 1520,
          "y" : 1178
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1522,
          "y" : 1174
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1522,
          "y" : 1174
        }
      }
    } ]
  }, {
    "id" : 82007,
    "reactomeId" : 10660994,
    "displayName" : "Properdin oligomer",
    "schemaClass" : "Polymer",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1740,
      "y" : 1190
    },
    "minX" : 1680,
    "maxX" : 1800,
    "minY" : 1158,
    "maxY" : 1202,
    "prop" : {
      "x" : 1680,
      "y" : 1179,
      "width" : 120,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1703,
      "y" : 1173
    },
    "connectors" : [ {
      "edgeId" : 82005,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1744,
          "y" : 1176
        },
        "to" : {
          "x" : 1753,
          "y" : 1158
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82006,
    "reactomeId" : 10660988,
    "displayName" : "Cell surface:C3b:Bb",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1649,
      "y" : 1145
    },
    "minX" : 1588,
    "maxX" : 1753,
    "minY" : 1128,
    "maxY" : 1178,
    "prop" : {
      "x" : 1588,
      "y" : 1134,
      "width" : 123,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1593,
      "y" : 1122
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1711,
          "y" : 1134
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1711,
          "y" : 1134
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82005,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1714,
          "y" : 1152
        },
        "to" : {
          "x" : 1753,
          "y" : 1158
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82020,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1636,
          "y" : 1160
        },
        "to" : {
          "x" : 1612,
          "y" : 1178
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1633,
          "y" : 1167
        },
        "b" : {
          "x" : 1636,
          "y" : 1160
        },
        "c" : {
          "x" : 1628,
          "y" : 1161
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1628,
          "y" : 1161
        }
      }
    } ]
  }, {
    "id" : 82008,
    "reactomeId" : 10660996,
    "displayName" : "Cell surface:C3b:Bb:Properdin",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1965,
      "y" : 1140
    },
    "minX" : 1902,
    "maxX" : 2077,
    "minY" : 1116,
    "maxY" : 1169,
    "prop" : {
      "x" : 1902,
      "y" : 1122,
      "width" : 127,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1909,
      "y" : 1124
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2029,
          "y" : 1122
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2029,
          "y" : 1122
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82005,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82009,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2012,
          "y" : 1162
        },
        "to" : {
          "x" : 2039,
          "y" : 1169
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82009,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2032,
          "y" : 1137
        },
        "to" : {
          "x" : 2072,
          "y" : 1136
        }
      }, {
        "from" : {
          "x" : 2072,
          "y" : 1136
        },
        "to" : {
          "x" : 2073,
          "y" : 1153
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2073,
          "y" : 1157
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2073,
          "y" : 1157
        }
      }
    } ]
  }, {
    "id" : 82011,
    "reactomeId" : 10660968,
    "displayName" : "Homologues of C3a",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2150,
      "y" : 1206
    },
    "minX" : 2108,
    "maxX" : 2166,
    "minY" : 1169,
    "maxY" : 1218,
    "prop" : {
      "x" : 2134,
      "y" : 1195,
      "width" : 32,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2134,
      "y" : 1161
    },
    "connectors" : [ {
      "edgeId" : 82009,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2136,
          "y" : 1192
        },
        "to" : {
          "x" : 2108,
          "y" : 1169
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2128,
          "y" : 1191
        },
        "b" : {
          "x" : 2136,
          "y" : 1192
        },
        "c" : {
          "x" : 2133,
          "y" : 1185
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2133,
          "y" : 1185
        }
      }
    } ]
  }, {
    "id" : 82010,
    "reactomeId" : 10662094,
    "displayName" : "C3b:Bb:C3b:Properdin",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2174,
      "y" : 1139
    },
    "minX" : 2108,
    "maxX" : 2222,
    "minY" : 1115,
    "maxY" : 1169,
    "prop" : {
      "x" : 2132,
      "y" : 1121,
      "width" : 84,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2132,
      "y" : 1123
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2216,
          "y" : 1121
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2216,
          "y" : 1121
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82009,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2133,
          "y" : 1161
        },
        "to" : {
          "x" : 2108,
          "y" : 1169
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2128,
          "y" : 1167
        },
        "b" : {
          "x" : 2133,
          "y" : 1161
        },
        "c" : {
          "x" : 2125,
          "y" : 1159
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2125,
          "y" : 1159
        }
      }
    } ]
  }, {
    "id" : 82013,
    "reactomeId" : 10660968,
    "displayName" : "Homologues of C3a",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 841,
      "y" : 1201
    },
    "minX" : 730,
    "maxX" : 864,
    "minY" : 1170,
    "maxY" : 1247,
    "prop" : {
      "x" : 825,
      "y" : 1190,
      "width" : 32,
      "height" : 23
    },
    "textPosition" : {
      "x" : 825,
      "y" : 1156
    },
    "connectors" : [ {
      "edgeId" : 82012,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 822,
          "y" : 1203
        },
        "to" : {
          "x" : 730,
          "y" : 1218
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 816,
          "y" : 1208
        },
        "b" : {
          "x" : 822,
          "y" : 1203
        },
        "c" : {
          "x" : 815,
          "y" : 1200
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 815,
          "y" : 1200
        }
      }
    }, {
      "edgeId" : 82016,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 822,
          "y" : 1207
        },
        "to" : {
          "x" : 735,
          "y" : 1247
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 817,
          "y" : 1214
        },
        "b" : {
          "x" : 822,
          "y" : 1207
        },
        "c" : {
          "x" : 814,
          "y" : 1206
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 814,
          "y" : 1206
        }
      }
    }, {
      "edgeId" : 82097,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 849,
          "y" : 1187
        },
        "to" : {
          "x" : 864,
          "y" : 1170
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82015,
    "reactomeId" : 10661002,
    "displayName" : "C3 convertases",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 691,
      "y" : 1140
    },
    "minX" : 643,
    "maxX" : 740,
    "minY" : 1129,
    "maxY" : 1210,
    "prop" : {
      "x" : 643,
      "y" : 1129,
      "width" : 97,
      "height" : 23
    },
    "textPosition" : {
      "x" : 649,
      "y" : 1123
    },
    "connectors" : [ {
      "edgeId" : 82012,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 690,
          "y" : 1158
        },
        "to" : {
          "x" : 688,
          "y" : 1194
        }
      }, {
        "from" : {
          "x" : 688,
          "y" : 1194
        },
        "to" : {
          "x" : 688,
          "y" : 1202
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 689,
          "y" : 1206
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 689,
          "y" : 1206
        }
      }
    } ]
  }, {
    "id" : 82014,
    "reactomeId" : 10660962,
    "displayName" : "C3b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 835,
      "y" : 1257
    },
    "minX" : 730,
    "maxX" : 1090,
    "minY" : 1187,
    "maxY" : 1269,
    "prop" : {
      "x" : 819,
      "y" : 1246,
      "width" : 33,
      "height" : 23
    },
    "textPosition" : {
      "x" : 819,
      "y" : 1248
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 852,
          "y" : 1246
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 852,
          "y" : 1246
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82012,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 816,
          "y" : 1250
        },
        "to" : {
          "x" : 730,
          "y" : 1218
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 808,
          "y" : 1251
        },
        "b" : {
          "x" : 816,
          "y" : 1250
        },
        "c" : {
          "x" : 811,
          "y" : 1244
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 811,
          "y" : 1244
        }
      }
    }, {
      "edgeId" : 82016,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 816,
          "y" : 1255
        },
        "to" : {
          "x" : 735,
          "y" : 1247
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 809,
          "y" : 1258
        },
        "b" : {
          "x" : 816,
          "y" : 1255
        },
        "c" : {
          "x" : 809,
          "y" : 1250
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 809,
          "y" : 1250
        }
      }
    }, {
      "edgeId" : 82036,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 855,
          "y" : 1252
        },
        "to" : {
          "x" : 1090,
          "y" : 1187
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82019,
    "reactomeId" : 10662853,
    "displayName" : "Cell surface:C3b:CFB",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1382,
      "y" : 1147
    },
    "minX" : 1318,
    "maxX" : 1453,
    "minY" : 1130,
    "maxY" : 1159,
    "prop" : {
      "x" : 1318,
      "y" : 1136,
      "width" : 129,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1326,
      "y" : 1124
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1447,
          "y" : 1136
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1447,
          "y" : 1136
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82017,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82020,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82018,
    "reactomeId" : 10660998,
    "displayName" : "Cell surface:C3b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1216,
      "y" : 1148
    },
    "minX" : 1164,
    "maxX" : 2313,
    "minY" : 1055,
    "maxY" : 1176,
    "prop" : {
      "x" : 1164,
      "y" : 1137,
      "width" : 104,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1173,
      "y" : 1125
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1268,
          "y" : 1137
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1268,
          "y" : 1137
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82017,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1246,
          "y" : 1163
        },
        "to" : {
          "x" : 1290,
          "y" : 1176
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82036,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82107,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1242,
          "y" : 1134
        },
        "to" : {
          "x" : 1431,
          "y" : 1056
        }
      }, {
        "from" : {
          "x" : 1431,
          "y" : 1056
        },
        "to" : {
          "x" : 2313,
          "y" : 1055
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82023,
    "reactomeId" : 10661000,
    "displayName" : "C4b:C2a:C3b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2116,
      "y" : 238
    },
    "minX" : 2072,
    "maxX" : 2166,
    "minY" : 221,
    "maxY" : 250,
    "prop" : {
      "x" : 2072,
      "y" : 227,
      "width" : 88,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2072,
      "y" : 229
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2160,
          "y" : 227
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2160,
          "y" : 227
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82021,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82022,
    "reactomeId" : 10660998,
    "displayName" : "Cell surface:C3b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2019,
      "y" : 238
    },
    "minX" : 1967,
    "maxX" : 2077,
    "minY" : 199,
    "maxY" : 250,
    "prop" : {
      "x" : 1967,
      "y" : 227,
      "width" : 104,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1976,
      "y" : 215
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2071,
          "y" : 227
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2071,
          "y" : 227
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82021,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2023,
          "y" : 224
        },
        "to" : {
          "x" : 2035,
          "y" : 199
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82025,
    "reactomeId" : 10661747,
    "displayName" : "c6.2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2486,
      "y" : 89
    },
    "minX" : 2474,
    "maxX" : 2522,
    "minY" : 72,
    "maxY" : 121,
    "prop" : {
      "x" : 2474,
      "y" : 78,
      "width" : 25,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2475,
      "y" : 72
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2499,
          "y" : 78
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2499,
          "y" : 78
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82024,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2502,
          "y" : 100
        },
        "to" : {
          "x" : 2522,
          "y" : 121
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82027,
    "reactomeId" : 10661749,
    "displayName" : "C5b:C6",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2533,
      "y" : 163
    },
    "minX" : 2495,
    "maxX" : 2566,
    "minY" : 146,
    "maxY" : 193,
    "prop" : {
      "x" : 2507,
      "y" : 152,
      "width" : 53,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2507,
      "y" : 154
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2560,
          "y" : 152
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2560,
          "y" : 152
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82024,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82028,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2518,
          "y" : 178
        },
        "to" : {
          "x" : 2495,
          "y" : 193
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82026,
    "reactomeId" : 10661743,
    "displayName" : "C5b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2452,
      "y" : 130
    },
    "minX" : 2436,
    "maxX" : 2522,
    "minY" : 113,
    "maxY" : 142,
    "prop" : {
      "x" : 2436,
      "y" : 119,
      "width" : 33,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2436,
      "y" : 121
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2469,
          "y" : 119
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2469,
          "y" : 119
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82024,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2472,
          "y" : 127
        },
        "to" : {
          "x" : 2522,
          "y" : 121
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82029,
    "reactomeId" : 10661755,
    "displayName" : "c7",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2460,
      "y" : 174
    },
    "minX" : 2448,
    "maxX" : 2495,
    "minY" : 157,
    "maxY" : 193,
    "prop" : {
      "x" : 2448,
      "y" : 163,
      "width" : 25,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2449,
      "y" : 164
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2473,
          "y" : 163
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2473,
          "y" : 163
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82028,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2476,
          "y" : 180
        },
        "to" : {
          "x" : 2495,
          "y" : 193
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82031,
    "reactomeId" : 10661767,
    "displayName" : "CLU:C5b:C6:C7, C8, C9",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2561,
      "y" : 621
    },
    "minX" : 2431,
    "maxX" : 2658,
    "minY" : 218,
    "maxY" : 640,
    "prop" : {
      "x" : 2496,
      "y" : 603,
      "width" : 131,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2496,
      "y" : 605
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2627,
          "y" : 603
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2627,
          "y" : 603
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82028,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 2579,
          "y" : 600
        },
        "to" : {
          "x" : 2657,
          "y" : 527
        }
      }, {
        "from" : {
          "x" : 2657,
          "y" : 527
        },
        "to" : {
          "x" : 2658,
          "y" : 274
        }
      }, {
        "from" : {
          "x" : 2658,
          "y" : 274
        },
        "to" : {
          "x" : 2504,
          "y" : 222
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2503,
          "y" : 226
        },
        "b" : {
          "x" : 2505,
          "y" : 218
        },
        "c" : {
          "x" : 2504,
          "y" : 222
        },
        "type" : "STOP",
        "centre" : {
          "x" : 2504,
          "y" : 222
        }
      }
    }, {
      "edgeId" : 82032,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 2544,
          "y" : 600
        },
        "to" : {
          "x" : 2434,
          "y" : 479
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2431,
          "y" : 482
        },
        "b" : {
          "x" : 2437,
          "y" : 476
        },
        "c" : {
          "x" : 2434,
          "y" : 479
        },
        "type" : "STOP",
        "centre" : {
          "x" : 2434,
          "y" : 479
        }
      }
    }, {
      "edgeId" : 82104,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82030,
    "reactomeId" : 10661757,
    "displayName" : "C5b:C6:C7",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2499,
      "y" : 293
    },
    "minX" : 2463,
    "maxX" : 2542,
    "minY" : 276,
    "maxY" : 356,
    "prop" : {
      "x" : 2463,
      "y" : 282,
      "width" : 73,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2463,
      "y" : 284
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2536,
          "y" : 282
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2536,
          "y" : 282
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82090,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2500,
          "y" : 308
        },
        "to" : {
          "x" : 2508,
          "y" : 356
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82028,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82032,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82035,
    "reactomeId" : 983438,
    "displayName" : "Cell surface",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1690,
      "y" : 236
    },
    "minX" : 1652,
    "maxX" : 1728,
    "minY" : 198,
    "maxY" : 248,
    "prop" : {
      "x" : 1652,
      "y" : 225,
      "width" : 76,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1662,
      "y" : 219
    },
    "connectors" : [ {
      "edgeId" : 82033,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1701,
          "y" : 222
        },
        "to" : {
          "x" : 1727,
          "y" : 198
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82034,
    "reactomeId" : 10679463,
    "displayName" : "C4A(20-675):C4A(1454-1744):S-(L-isoglutamyl)-L-cysteine-C4A(757-1446)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1708,
      "y" : 107
    },
    "minX" : 1692,
    "maxX" : 1731,
    "minY" : 90,
    "maxY" : 198,
    "prop" : {
      "x" : 1692,
      "y" : 96,
      "width" : 33,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1692,
      "y" : -57
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1725,
          "y" : 96
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1725,
          "y" : 96
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82033,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1710,
          "y" : 125
        },
        "to" : {
          "x" : 1727,
          "y" : 198
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82037,
    "reactomeId" : 983438,
    "displayName" : "Cell surface",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1078,
      "y" : 1142
    },
    "minX" : 1040,
    "maxX" : 1116,
    "minY" : 1131,
    "maxY" : 1187,
    "prop" : {
      "x" : 1040,
      "y" : 1131,
      "width" : 76,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1050,
      "y" : 1125
    },
    "connectors" : [ {
      "edgeId" : 82036,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1081,
          "y" : 1157
        },
        "to" : {
          "x" : 1090,
          "y" : 1187
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82039,
    "reactomeId" : 10661002,
    "displayName" : "C3 convertases",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2730,
      "y" : 263
    },
    "minX" : 2682,
    "maxX" : 2779,
    "minY" : 252,
    "maxY" : 275,
    "prop" : {
      "x" : 2682,
      "y" : 252,
      "width" : 97,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2688,
      "y" : 246
    },
    "connectors" : [ {
      "edgeId" : 82038,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82041,
    "reactomeId" : 10660910,
    "displayName" : "c2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2892,
      "y" : 163
    },
    "minX" : 2856,
    "maxX" : 2914,
    "minY" : 146,
    "maxY" : 208,
    "prop" : {
      "x" : 2876,
      "y" : 152,
      "width" : 32,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2880,
      "y" : 153
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2908,
          "y" : 152
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2908,
          "y" : 152
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82038,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2882,
          "y" : 178
        },
        "to" : {
          "x" : 2856,
          "y" : 208
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2880,
          "y" : 186
        },
        "b" : {
          "x" : 2882,
          "y" : 178
        },
        "c" : {
          "x" : 2874,
          "y" : 181
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2874,
          "y" : 181
        }
      }
    } ]
  }, {
    "id" : 82040,
    "reactomeId" : 10660982,
    "displayName" : "cfb",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3161,
      "y" : 263
    },
    "minX" : 2711,
    "maxX" : 3214,
    "minY" : 208,
    "maxY" : 1053,
    "prop" : {
      "x" : 3115,
      "y" : 252,
      "width" : 93,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3148,
      "y" : 253
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3208,
          "y" : 252
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3208,
          "y" : 252
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82059,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3154,
          "y" : 278
        },
        "to" : {
          "x" : 2711,
          "y" : 1053
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3154,
          "y" : 286
        },
        "b" : {
          "x" : 3154,
          "y" : 278
        },
        "c" : {
          "x" : 3147,
          "y" : 282
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3147,
          "y" : 282
        }
      }
    }, {
      "edgeId" : 82038,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3112,
          "y" : 254
        },
        "to" : {
          "x" : 2856,
          "y" : 208
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 2978,
            "y" : 225
          },
          "b" : {
            "x" : 2990,
            "y" : 237
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2984,
            "y" : 231
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 3104,
          "y" : 257
        },
        "b" : {
          "x" : 3112,
          "y" : 254
        },
        "c" : {
          "x" : 3106,
          "y" : 249
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3106,
          "y" : 249
        }
      }
    } ]
  }, {
    "id" : 82043,
    "reactomeId" : 10660932,
    "displayName" : "Cell surface:C4b:C2a",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2873,
      "y" : 268
    },
    "minX" : 2808,
    "maxX" : 2945,
    "minY" : 208,
    "maxY" : 280,
    "prop" : {
      "x" : 2808,
      "y" : 257,
      "width" : 131,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2817,
      "y" : 245
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2939,
          "y" : 257
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2939,
          "y" : 257
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82038,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2869,
          "y" : 254
        },
        "to" : {
          "x" : 2856,
          "y" : 208
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2863,
          "y" : 248
        },
        "b" : {
          "x" : 2869,
          "y" : 254
        },
        "c" : {
          "x" : 2871,
          "y" : 246
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2871,
          "y" : 246
        }
      }
    } ]
  }, {
    "id" : 82042,
    "reactomeId" : 10660930,
    "displayName" : "Cell surface:C4b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3033,
      "y" : 269
    },
    "minX" : 2856,
    "maxX" : 3091,
    "minY" : 208,
    "maxY" : 281,
    "prop" : {
      "x" : 2981,
      "y" : 258,
      "width" : 104,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2990,
      "y" : 246
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3085,
          "y" : 258
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3085,
          "y" : 258
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82038,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2999,
          "y" : 255
        },
        "to" : {
          "x" : 2856,
          "y" : 208
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2991,
          "y" : 257
        },
        "b" : {
          "x" : 2999,
          "y" : 255
        },
        "c" : {
          "x" : 2994,
          "y" : 249
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2994,
          "y" : 249
        }
      }
    } ]
  }, {
    "id" : 82045,
    "reactomeId" : 10660962,
    "displayName" : "C3b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3085,
      "y" : 206
    },
    "minX" : 2856,
    "maxX" : 3108,
    "minY" : 189,
    "maxY" : 218,
    "prop" : {
      "x" : 3069,
      "y" : 195,
      "width" : 33,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3069,
      "y" : 197
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3102,
          "y" : 195
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3102,
          "y" : 195
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82038,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3066,
          "y" : 206
        },
        "to" : {
          "x" : 2856,
          "y" : 208
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 2955,
            "y" : 201
          },
          "b" : {
            "x" : 2967,
            "y" : 213
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2961,
            "y" : 207
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 3059,
          "y" : 210
        },
        "b" : {
          "x" : 3066,
          "y" : 206
        },
        "c" : {
          "x" : 3059,
          "y" : 202
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3059,
          "y" : 202
        }
      }
    } ]
  }, {
    "id" : 82044,
    "reactomeId" : 10660978,
    "displayName" : "C3(H2O)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2963,
      "y" : 162
    },
    "minX" : 2856,
    "maxX" : 2999,
    "minY" : 145,
    "maxY" : 208,
    "prop" : {
      "x" : 2934,
      "y" : 151,
      "width" : 59,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2941,
      "y" : 139
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2993,
          "y" : 151
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2993,
          "y" : 151
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82038,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2936,
          "y" : 177
        },
        "to" : {
          "x" : 2856,
          "y" : 208
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2931,
          "y" : 183
        },
        "b" : {
          "x" : 2936,
          "y" : 177
        },
        "c" : {
          "x" : 2928,
          "y" : 176
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2928,
          "y" : 176
        }
      }
    } ]
  }, {
    "id" : 82046,
    "reactomeId" : 10660994,
    "displayName" : "Properdin oligomer",
    "schemaClass" : "Polymer",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 3087,
      "y" : 162
    },
    "minX" : 2856,
    "maxX" : 3147,
    "minY" : 151,
    "maxY" : 208,
    "prop" : {
      "x" : 3027,
      "y" : 151,
      "width" : 120,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3050,
      "y" : 145
    },
    "connectors" : [ {
      "edgeId" : 82038,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3024,
          "y" : 173
        },
        "to" : {
          "x" : 2856,
          "y" : 208
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3018,
          "y" : 178
        },
        "b" : {
          "x" : 3024,
          "y" : 173
        },
        "c" : {
          "x" : 3016,
          "y" : 170
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3016,
          "y" : 170
        }
      }
    } ]
  }, {
    "id" : 82049,
    "reactomeId" : 10679233,
    "displayName" : "Homologues of CFH",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 3123,
      "y" : 1134
    },
    "minX" : 3076,
    "maxX" : 3176,
    "minY" : 1115,
    "maxY" : 1229,
    "prop" : {
      "x" : 3107,
      "y" : 1123,
      "width" : 32,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3107,
      "y" : 1089
    },
    "connectors" : [ {
      "edgeId" : 82071,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3142,
          "y" : 1128
        },
        "to" : {
          "x" : 3176,
          "y" : 1115
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82088,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3117,
          "y" : 1149
        },
        "to" : {
          "x" : 3076,
          "y" : 1229
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3117,
          "y" : 1157
        },
        "b" : {
          "x" : 3117,
          "y" : 1149
        },
        "c" : {
          "x" : 3110,
          "y" : 1153
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3110,
          "y" : 1153
        }
      }
    }, {
      "edgeId" : 82047,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3142,
          "y" : 1140
        },
        "to" : {
          "x" : 3174,
          "y" : 1155
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82048,
    "reactomeId" : 10660962,
    "displayName" : "C3b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3139,
      "y" : 1181
    },
    "minX" : 3123,
    "maxX" : 3174,
    "minY" : 1155,
    "maxY" : 1193,
    "prop" : {
      "x" : 3123,
      "y" : 1170,
      "width" : 33,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3123,
      "y" : 1172
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3156,
          "y" : 1170
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3156,
          "y" : 1170
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82047,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3154,
          "y" : 1167
        },
        "to" : {
          "x" : 3174,
          "y" : 1155
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82050,
    "reactomeId" : 10679235,
    "displayName" : "CFH:C3b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3283,
      "y" : 1156
    },
    "minX" : 3253,
    "maxX" : 3319,
    "minY" : 1139,
    "maxY" : 1231,
    "prop" : {
      "x" : 3253,
      "y" : 1145,
      "width" : 60,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3253,
      "y" : 1147
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3313,
          "y" : 1145
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3313,
          "y" : 1145
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82064,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3286,
          "y" : 1171
        },
        "to" : {
          "x" : 3307,
          "y" : 1231
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82047,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82053,
    "reactomeId" : 10660998,
    "displayName" : "Cell surface:C3b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2681,
      "y" : 749
    },
    "minX" : 2629,
    "maxX" : 2749,
    "minY" : 732,
    "maxY" : 804,
    "prop" : {
      "x" : 2629,
      "y" : 738,
      "width" : 104,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2638,
      "y" : 726
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2733,
          "y" : 738
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2733,
          "y" : 738
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82051,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2695,
          "y" : 764
        },
        "to" : {
          "x" : 2749,
          "y" : 804
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82052,
    "reactomeId" : 10679368,
    "displayName" : "CFH, CFHR3",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2583,
      "y" : 788
    },
    "minX" : 2544,
    "maxX" : 2749,
    "minY" : 777,
    "maxY" : 878,
    "prop" : {
      "x" : 2544,
      "y" : 777,
      "width" : 79,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2559,
      "y" : 771
    },
    "connectors" : [ {
      "edgeId" : 82051,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2629,
          "y" : 791
        },
        "to" : {
          "x" : 2749,
          "y" : 804
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82056,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2590,
          "y" : 806
        },
        "to" : {
          "x" : 2644,
          "y" : 878
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82055,
    "reactomeId" : 10679378,
    "displayName" : "CFH:Host cell surface",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3273,
      "y" : 1081
    },
    "minX" : 2651,
    "maxX" : 3345,
    "minY" : 921,
    "maxY" : 1093,
    "prop" : {
      "x" : 3208,
      "y" : 1070,
      "width" : 131,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3226,
      "y" : 1058
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3339,
          "y" : 1070
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3339,
          "y" : 1070
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82051,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 3235,
          "y" : 1067
        },
        "to" : {
          "x" : 2760,
          "y" : 925
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2768,
          "y" : 923
        },
        "b" : {
          "x" : 2760,
          "y" : 925
        },
        "c" : {
          "x" : 2765,
          "y" : 931
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 2765,
          "y" : 931
        }
      }
    }, {
      "edgeId" : 82056,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 3227,
          "y" : 1067
        },
        "to" : {
          "x" : 2651,
          "y" : 923
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2659,
          "y" : 921
        },
        "b" : {
          "x" : 2651,
          "y" : 923
        },
        "c" : {
          "x" : 2657,
          "y" : 929
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 2657,
          "y" : 929
        }
      }
    }, {
      "edgeId" : 82071,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82054,
    "reactomeId" : 10679370,
    "displayName" : "Cell surface:FH,FHR3:C3b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2721,
      "y" : 1094
    },
    "minX" : 2672,
    "maxX" : 2777,
    "minY" : 1053,
    "maxY" : 1128,
    "prop" : {
      "x" : 2672,
      "y" : 1076,
      "width" : 99,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2677,
      "y" : 1078
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2771,
          "y" : 1076
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2771,
          "y" : 1076
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82051,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82059,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2716,
          "y" : 1073
        },
        "to" : {
          "x" : 2711,
          "y" : 1053
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2710,
          "y" : 1067
        },
        "b" : {
          "x" : 2716,
          "y" : 1073
        },
        "c" : {
          "x" : 2718,
          "y" : 1065
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2718,
          "y" : 1065
        }
      }
    }, {
      "edgeId" : 82066,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2749,
          "y" : 1116
        },
        "to" : {
          "x" : 2773,
          "y" : 1128
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82057,
    "reactomeId" : 10660988,
    "displayName" : "Cell surface:C3b:Bb",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2679,
      "y" : 835
    },
    "minX" : 2618,
    "maxX" : 2747,
    "minY" : 818,
    "maxY" : 878,
    "prop" : {
      "x" : 2618,
      "y" : 824,
      "width" : 123,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2623,
      "y" : 812
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2741,
          "y" : 824
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2741,
          "y" : 824
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82056,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2669,
          "y" : 850
        },
        "to" : {
          "x" : 2644,
          "y" : 878
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82058,
    "reactomeId" : 10679376,
    "displayName" : "Cell surface:CFH, CFHR3:C3bBb",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2671,
      "y" : 985
    },
    "minX" : 2616,
    "maxX" : 2733,
    "minY" : 961,
    "maxY" : 1004,
    "prop" : {
      "x" : 2616,
      "y" : 967,
      "width" : 111,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2629,
      "y" : 955
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2727,
          "y" : 967
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2727,
          "y" : 967
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82056,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82059,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82061,
    "reactomeId" : 10679239,
    "displayName" : "cfi",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3782,
      "y" : 1316
    },
    "minX" : 3689,
    "maxX" : 3829,
    "minY" : 1299,
    "maxY" : 1343,
    "prop" : {
      "x" : 3742,
      "y" : 1305,
      "width" : 81,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3771,
      "y" : 1306
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3823,
          "y" : 1305
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3823,
          "y" : 1305
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82060,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3739,
          "y" : 1327
        },
        "to" : {
          "x" : 3689,
          "y" : 1343
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82063,
    "reactomeId" : 10679243,
    "displayName" : "CFI",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3463,
      "y" : 1341
    },
    "minX" : 2773,
    "maxX" : 3482,
    "minY" : 1128,
    "maxY" : 1353,
    "prop" : {
      "x" : 3450,
      "y" : 1330,
      "width" : 26,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3450,
      "y" : 1332
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3476,
          "y" : 1330
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3476,
          "y" : 1330
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82060,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82064,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3447,
          "y" : 1331
        },
        "to" : {
          "x" : 3307,
          "y" : 1231
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82066,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3447,
          "y" : 1341
        },
        "to" : {
          "x" : 2883,
          "y" : 1341
        }
      }, {
        "from" : {
          "x" : 2883,
          "y" : 1341
        },
        "to" : {
          "x" : 2773,
          "y" : 1128
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82088,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3447,
          "y" : 1339
        },
        "to" : {
          "x" : 3086,
          "y" : 1304
        }
      }, {
        "from" : {
          "x" : 3086,
          "y" : 1304
        },
        "to" : {
          "x" : 3076,
          "y" : 1229
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3440,
          "y" : 1342
        },
        "b" : {
          "x" : 3447,
          "y" : 1339
        },
        "c" : {
          "x" : 3440,
          "y" : 1334
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3440,
          "y" : 1334
        }
      }
    } ]
  }, {
    "id" : 82062,
    "reactomeId" : 10679241,
    "displayName" : "cfi",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3778,
      "y" : 1364
    },
    "minX" : 3689,
    "maxX" : 3829,
    "minY" : 1343,
    "maxY" : 1376,
    "prop" : {
      "x" : 3734,
      "y" : 1353,
      "width" : 89,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3767,
      "y" : 1354
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3823,
          "y" : 1353
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3823,
          "y" : 1353
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82060,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3731,
          "y" : 1353
        },
        "to" : {
          "x" : 3689,
          "y" : 1343
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82065,
    "reactomeId" : 10679245,
    "displayName" : "CFI:CFH:C3b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3196,
      "y" : 1231
    },
    "minX" : 3100,
    "maxX" : 3243,
    "minY" : 1214,
    "maxY" : 1266,
    "prop" : {
      "x" : 3156,
      "y" : 1220,
      "width" : 81,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3167,
      "y" : 1208
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3237,
          "y" : 1220
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3237,
          "y" : 1220
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82064,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82088,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82088,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3166,
          "y" : 1246
        },
        "to" : {
          "x" : 3107,
          "y" : 1266
        }
      }, {
        "from" : {
          "x" : 3107,
          "y" : 1266
        },
        "to" : {
          "x" : 3105,
          "y" : 1245
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3104,
          "y" : 1241
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3104,
          "y" : 1241
        }
      }
    } ]
  }, {
    "id" : 82067,
    "reactomeId" : 10679372,
    "displayName" : "CFI:CFH,FHR3:C3b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2851,
      "y" : 1085
    },
    "minX" : 2793,
    "maxX" : 2940,
    "minY" : 1068,
    "maxY" : 1121,
    "prop" : {
      "x" : 2793,
      "y" : 1074,
      "width" : 116,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2804,
      "y" : 1062
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2909,
          "y" : 1074
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2909,
          "y" : 1074
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82066,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82068,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 82068,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2878,
          "y" : 1100
        },
        "to" : {
          "x" : 2936,
          "y" : 1121
        }
      }, {
        "from" : {
          "x" : 2936,
          "y" : 1121
        },
        "to" : {
          "x" : 2936,
          "y" : 1102
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2936,
          "y" : 1098
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2936,
          "y" : 1098
        }
      }
    } ]
  }, {
    "id" : 82069,
    "reactomeId" : 10679407,
    "displayName" : "CFI:CFH,FHR3:iC3b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3033,
      "y" : 1085
    },
    "minX" : 2955,
    "maxX" : 3099,
    "minY" : 1068,
    "maxY" : 1097,
    "prop" : {
      "x" : 2974,
      "y" : 1074,
      "width" : 119,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2986,
      "y" : 1062
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3093,
          "y" : 1074
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3093,
          "y" : 1074
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82068,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2971,
          "y" : 1085
        },
        "to" : {
          "x" : 2955,
          "y" : 1085
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2964,
          "y" : 1089
        },
        "b" : {
          "x" : 2971,
          "y" : 1085
        },
        "c" : {
          "x" : 2964,
          "y" : 1081
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2964,
          "y" : 1081
        }
      }
    } ]
  }, {
    "id" : 82070,
    "reactomeId" : 10679265,
    "displayName" : "Homologues of C3f",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 3014,
      "y" : 1144
    },
    "minX" : 2955,
    "maxX" : 3076,
    "minY" : 1085,
    "maxY" : 1229,
    "prop" : {
      "x" : 3000,
      "y" : 1133,
      "width" : 29,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3000,
      "y" : 1092
    },
    "connectors" : [ {
      "edgeId" : 82068,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3002,
          "y" : 1130
        },
        "to" : {
          "x" : 2955,
          "y" : 1085
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2994,
          "y" : 1128
        },
        "b" : {
          "x" : 3002,
          "y" : 1130
        },
        "c" : {
          "x" : 3000,
          "y" : 1122
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3000,
          "y" : 1122
        }
      }
    }, {
      "edgeId" : 82088,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3022,
          "y" : 1159
        },
        "to" : {
          "x" : 3076,
          "y" : 1229
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3029,
          "y" : 1162
        },
        "b" : {
          "x" : 3022,
          "y" : 1159
        },
        "c" : {
          "x" : 3023,
          "y" : 1167
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3023,
          "y" : 1167
        }
      }
    } ]
  }, {
    "id" : 82072,
    "reactomeId" : 1006146,
    "displayName" : "Host cell surface",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3156,
      "y" : 1083
    },
    "minX" : 3104,
    "maxX" : 3214,
    "minY" : 1066,
    "maxY" : 1115,
    "prop" : {
      "x" : 3104,
      "y" : 1072,
      "width" : 104,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3123,
      "y" : 1060
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3208,
          "y" : 1072
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3208,
          "y" : 1072
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82071,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3163,
          "y" : 1098
        },
        "to" : {
          "x" : 3176,
          "y" : 1115
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82075,
    "reactomeId" : 2855114,
    "displayName" : "FCN1 ligands",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 232,
      "y" : 750
    },
    "minX" : 151,
    "maxX" : 275,
    "minY" : 739,
    "maxY" : 766,
    "prop" : {
      "x" : 190,
      "y" : 739,
      "width" : 85,
      "height" : 23
    },
    "textPosition" : {
      "x" : 206,
      "y" : 733
    },
    "connectors" : [ {
      "edgeId" : 82073,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 184,
          "y" : 758
        },
        "to" : {
          "x" : 151,
          "y" : 766
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82074,
    "reactomeId" : 10691860,
    "displayName" : "FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 58,
      "y" : 751
    },
    "minX" : 1,
    "maxX" : 151,
    "minY" : 720,
    "maxY" : 777,
    "prop" : {
      "x" : 1,
      "y" : 726,
      "width" : 114,
      "height" : 51
    },
    "textPosition" : {
      "x" : 7,
      "y" : 714
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 115,
          "y" : 726
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 115,
          "y" : 726
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82073,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 118,
          "y" : 760
        },
        "to" : {
          "x" : 151,
          "y" : 766
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82077,
    "reactomeId" : 10691862,
    "displayName" : "FCN1 ligands:FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 242,
      "y" : 813
    },
    "minX" : 180,
    "maxX" : 310,
    "minY" : 775,
    "maxY" : 846,
    "prop" : {
      "x" : 180,
      "y" : 781,
      "width" : 124,
      "height" : 65
    },
    "textPosition" : {
      "x" : 182,
      "y" : 769
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 304,
          "y" : 781
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 304,
          "y" : 781
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82073,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82076,
    "reactomeId" : 74112,
    "displayName" : "Ca2+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 153,
      "y" : 711
    },
    "minX" : 128,
    "maxX" : 179,
    "minY" : 695,
    "maxY" : 766,
    "prop" : {
      "x" : 128,
      "y" : 696,
      "width" : 50,
      "height" : 31
    },
    "textPosition" : {
      "x" : 132,
      "y" : 701
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 173,
          "y" : 701
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 173,
          "y" : 701
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82073,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 152,
          "y" : 730
        },
        "to" : {
          "x" : 151,
          "y" : 766
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 145,
            "y" : 742
          },
          "b" : {
            "x" : 157,
            "y" : 754
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 151,
            "y" : 748
          }
        }
      }
    } ]
  }, {
    "id" : 82079,
    "reactomeId" : 2855063,
    "displayName" : "FCN2 ligands",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 237,
      "y" : 891
    },
    "minX" : 148,
    "maxX" : 280,
    "minY" : 880,
    "maxY" : 919,
    "prop" : {
      "x" : 195,
      "y" : 880,
      "width" : 85,
      "height" : 23
    },
    "textPosition" : {
      "x" : 211,
      "y" : 874
    },
    "connectors" : [ {
      "edgeId" : 82078,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 200,
          "y" : 909
        },
        "to" : {
          "x" : 148,
          "y" : 919
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82081,
    "reactomeId" : 74112,
    "displayName" : "Ca2+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 149,
      "y" : 870
    },
    "minX" : 124,
    "maxX" : 175,
    "minY" : 854,
    "maxY" : 919,
    "prop" : {
      "x" : 124,
      "y" : 855,
      "width" : 50,
      "height" : 31
    },
    "textPosition" : {
      "x" : 128,
      "y" : 860
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 169,
          "y" : 860
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 169,
          "y" : 860
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82078,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 148,
          "y" : 889
        },
        "to" : {
          "x" : 148,
          "y" : 919
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 142,
            "y" : 898
          },
          "b" : {
            "x" : 154,
            "y" : 910
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 148,
            "y" : 904
          }
        }
      }
    } ]
  }, {
    "id" : 82080,
    "reactomeId" : 10691834,
    "displayName" : "FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 57,
      "y" : 902
    },
    "minX" : 0,
    "maxX" : 148,
    "minY" : 871,
    "maxY" : 928,
    "prop" : {
      "x" : 0,
      "y" : 877,
      "width" : 114,
      "height" : 51
    },
    "textPosition" : {
      "x" : 6,
      "y" : 865
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 114,
          "y" : 877
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 114,
          "y" : 877
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82078,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 117,
          "y" : 912
        },
        "to" : {
          "x" : 148,
          "y" : 919
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82082,
    "reactomeId" : 10691836,
    "displayName" : "FCN2 ligands:FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 239,
      "y" : 949
    },
    "minX" : 177,
    "maxX" : 307,
    "minY" : 911,
    "maxY" : 982,
    "prop" : {
      "x" : 177,
      "y" : 917,
      "width" : 124,
      "height" : 65
    },
    "textPosition" : {
      "x" : 179,
      "y" : 905
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 301,
          "y" : 917
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 301,
          "y" : 917
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82078,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82085,
    "reactomeId" : 10691848,
    "displayName" : "FCN3 oligomer:MASP1 dimer:MASP2-1 dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 68,
      "y" : 1051
    },
    "minX" : 18,
    "maxX" : 163,
    "minY" : 1020,
    "maxY" : 1077,
    "prop" : {
      "x" : 18,
      "y" : 1026,
      "width" : 101,
      "height" : 51
    },
    "textPosition" : {
      "x" : 18,
      "y" : 1014
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 119,
          "y" : 1026
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 119,
          "y" : 1026
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82083,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 122,
          "y" : 1056
        },
        "to" : {
          "x" : 163,
          "y" : 1061
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82084,
    "reactomeId" : 2855098,
    "displayName" : "FCN3 ligands",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 240,
      "y" : 1042
    },
    "minX" : 163,
    "maxX" : 283,
    "minY" : 1031,
    "maxY" : 1061,
    "prop" : {
      "x" : 198,
      "y" : 1031,
      "width" : 85,
      "height" : 23
    },
    "textPosition" : {
      "x" : 214,
      "y" : 1025
    },
    "connectors" : [ {
      "edgeId" : 82083,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 192,
          "y" : 1052
        },
        "to" : {
          "x" : 163,
          "y" : 1061
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82087,
    "reactomeId" : 10691850,
    "displayName" : "FCN3 ligands:FCN3 multimer:MASP1 dimer:MASP2 dimer:4xCa2+",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 247,
      "y" : 1103
    },
    "minX" : 183,
    "maxX" : 317,
    "minY" : 1065,
    "maxY" : 1136,
    "prop" : {
      "x" : 183,
      "y" : 1071,
      "width" : 128,
      "height" : 65
    },
    "textPosition" : {
      "x" : 183,
      "y" : 1073
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 311,
          "y" : 1071
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 311,
          "y" : 1071
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82083,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82086,
    "reactomeId" : 74112,
    "displayName" : "Ca2+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 162,
      "y" : 1014
    },
    "minX" : 137,
    "maxX" : 188,
    "minY" : 998,
    "maxY" : 1061,
    "prop" : {
      "x" : 137,
      "y" : 999,
      "width" : 50,
      "height" : 31
    },
    "textPosition" : {
      "x" : 141,
      "y" : 1004
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 182,
          "y" : 1004
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 182,
          "y" : 1004
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82083,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 162,
          "y" : 1033
        },
        "to" : {
          "x" : 163,
          "y" : 1061
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 156,
            "y" : 1041
          },
          "b" : {
            "x" : 168,
            "y" : 1053
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 162,
            "y" : 1047
          }
        }
      }
    } ]
  }, {
    "id" : 82089,
    "reactomeId" : 10679259,
    "displayName" : "iC3b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3018,
      "y" : 1263
    },
    "minX" : 3000,
    "maxX" : 3076,
    "minY" : 1229,
    "maxY" : 1275,
    "prop" : {
      "x" : 3000,
      "y" : 1252,
      "width" : 36,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3000,
      "y" : 1254
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3036,
          "y" : 1252
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3036,
          "y" : 1252
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82088,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3039,
          "y" : 1252
        },
        "to" : {
          "x" : 3076,
          "y" : 1229
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3043,
          "y" : 1245
        },
        "b" : {
          "x" : 3039,
          "y" : 1252
        },
        "c" : {
          "x" : 3047,
          "y" : 1252
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3047,
          "y" : 1252
        }
      }
    } ]
  }, {
    "id" : 82091,
    "reactomeId" : 10667687,
    "displayName" : "vtn",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2548,
      "y" : 332
    },
    "minX" : 2508,
    "maxX" : 2571,
    "minY" : 315,
    "maxY" : 356,
    "prop" : {
      "x" : 2531,
      "y" : 321,
      "width" : 34,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2534,
      "y" : 322
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2565,
          "y" : 321
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2565,
          "y" : 321
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82090,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2528,
          "y" : 342
        },
        "to" : {
          "x" : 2508,
          "y" : 356
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82092,
    "reactomeId" : 10691133,
    "displayName" : "VTN:C5b:C6:C7",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2509,
      "y" : 431
    },
    "minX" : 2458,
    "maxX" : 2566,
    "minY" : 414,
    "maxY" : 443,
    "prop" : {
      "x" : 2458,
      "y" : 420,
      "width" : 102,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2459,
      "y" : 422
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2560,
          "y" : 420
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2560,
          "y" : 420
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82090,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82095,
    "reactomeId" : 10679463,
    "displayName" : "C4A(20-675):C4A(1454-1744):S-(L-isoglutamyl)-L-cysteine-C4A(757-1446)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 4617,
      "y" : 785
    },
    "minX" : 4601,
    "maxX" : 4671,
    "minY" : 768,
    "maxY" : 836,
    "prop" : {
      "x" : 4601,
      "y" : 774,
      "width" : 33,
      "height" : 23
    },
    "textPosition" : {
      "x" : 4601,
      "y" : 621
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4634,
          "y" : 774
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4634,
          "y" : 774
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82093,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4629,
          "y" : 803
        },
        "to" : {
          "x" : 4671,
          "y" : 836
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82094,
    "reactomeId" : 109276,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 4711,
      "y" : 814
    },
    "minX" : 4671,
    "maxX" : 4734,
    "minY" : 798,
    "maxY" : 836,
    "prop" : {
      "x" : 4690,
      "y" : 799,
      "width" : 43,
      "height" : 31
    },
    "textPosition" : {
      "x" : 4694,
      "y" : 804
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4728,
          "y" : 804
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4728,
          "y" : 804
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82093,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 4687,
          "y" : 825
        },
        "to" : {
          "x" : 4671,
          "y" : 836
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 82096,
    "reactomeId" : 10660921,
    "displayName" : "deamidated-Q1013-C4A-derived C4b",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 4674,
      "y" : 921
    },
    "minX" : 4609,
    "maxX" : 4746,
    "minY" : 897,
    "maxY" : 940,
    "prop" : {
      "x" : 4609,
      "y" : 903,
      "width" : 131,
      "height" : 37
    },
    "textPosition" : {
      "x" : 4609,
      "y" : 897
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 4740,
          "y" : 903
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 4740,
          "y" : 903
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82093,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82099,
    "reactomeId" : 10669715,
    "displayName" : "C3AR1:C3a",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 961,
      "y" : 1142
    },
    "minX" : 923,
    "maxX" : 1005,
    "minY" : 1125,
    "maxY" : 1154,
    "prop" : {
      "x" : 923,
      "y" : 1131,
      "width" : 76,
      "height" : 23
    },
    "textPosition" : {
      "x" : 923,
      "y" : 1133
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 999,
          "y" : 1131
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 999,
          "y" : 1131
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82097,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82098,
    "reactomeId" : 10669713,
    "displayName" : "c3ar1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 842,
      "y" : 1143
    },
    "minX" : 818,
    "maxX" : 873,
    "minY" : 1126,
    "maxY" : 1170,
    "prop" : {
      "x" : 818,
      "y" : 1132,
      "width" : 49,
      "height" : 23
    },
    "textPosition" : {
      "x" : 820,
      "y" : 1133
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 867,
          "y" : 1132
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 867,
          "y" : 1132
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82097,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 851,
          "y" : 1158
        },
        "to" : {
          "x" : 864,
          "y" : 1170
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82101,
    "reactomeId" : 10678913,
    "displayName" : "c5ar1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 383,
      "y" : 1139
    },
    "minX" : 359,
    "maxX" : 433,
    "minY" : 1122,
    "maxY" : 1164,
    "prop" : {
      "x" : 359,
      "y" : 1128,
      "width" : 49,
      "height" : 23
    },
    "textPosition" : {
      "x" : 361,
      "y" : 1129
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 408,
          "y" : 1128
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 408,
          "y" : 1128
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82100,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 406,
          "y" : 1154
        },
        "to" : {
          "x" : 433,
          "y" : 1164
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82103,
    "reactomeId" : 10678915,
    "displayName" : "C5AR2:C5AR2 ligands",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 554,
      "y" : 1144
    },
    "minX" : 506,
    "maxX" : 609,
    "minY" : 1120,
    "maxY" : 1163,
    "prop" : {
      "x" : 506,
      "y" : 1126,
      "width" : 97,
      "height" : 37
    },
    "textPosition" : {
      "x" : 506,
      "y" : 1128
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 603,
          "y" : 1126
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 603,
          "y" : 1126
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82100,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82102,
    "reactomeId" : 10678911,
    "displayName" : "C5AR2 ligands",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 389,
      "y" : 1200
    },
    "minX" : 342,
    "maxX" : 436,
    "minY" : 1164,
    "maxY" : 1212,
    "prop" : {
      "x" : 342,
      "y" : 1189,
      "width" : 94,
      "height" : 23
    },
    "textPosition" : {
      "x" : 362,
      "y" : 1183
    },
    "connectors" : [ {
      "edgeId" : 82100,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 403,
          "y" : 1183
        },
        "to" : {
          "x" : 433,
          "y" : 1164
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82105,
    "reactomeId" : 10661765,
    "displayName" : "CLU",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2614,
      "y" : 482
    },
    "minX" : 2561,
    "maxX" : 2636,
    "minY" : 465,
    "maxY" : 530,
    "prop" : {
      "x" : 2599,
      "y" : 471,
      "width" : 31,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2599,
      "y" : 473
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2630,
          "y" : 471
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2630,
          "y" : 471
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82104,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2601,
          "y" : 497
        },
        "to" : {
          "x" : 2561,
          "y" : 530
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82106,
    "reactomeId" : 10661757,
    "displayName" : "C5b:C6:C7",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2532,
      "y" : 488
    },
    "minX" : 2472,
    "maxX" : 2599,
    "minY" : 471,
    "maxY" : 530,
    "prop" : {
      "x" : 2472,
      "y" : 477,
      "width" : 121,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2496,
      "y" : 478
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2593,
          "y" : 477
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2593,
          "y" : 477
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82104,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2539,
          "y" : 506
        },
        "to" : {
          "x" : 2561,
          "y" : 530
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82109,
    "reactomeId" : 10712514,
    "displayName" : "Cell surface:C3b:CFHR dimers",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2289,
      "y" : 1138
    },
    "minX" : 2235,
    "maxX" : 2349,
    "minY" : 1114,
    "maxY" : 1157,
    "prop" : {
      "x" : 2235,
      "y" : 1120,
      "width" : 108,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2246,
      "y" : 1108
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2343,
          "y" : 1120
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2343,
          "y" : 1120
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82107,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82108,
    "reactomeId" : 10712512,
    "displayName" : "CFHR dimers",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2342,
      "y" : 1006
    },
    "minX" : 2300,
    "maxX" : 2384,
    "minY" : 995,
    "maxY" : 1055,
    "prop" : {
      "x" : 2300,
      "y" : 995,
      "width" : 84,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2317,
      "y" : 989
    },
    "connectors" : [ {
      "edgeId" : 82107,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2335,
          "y" : 1024
        },
        "to" : {
          "x" : 2313,
          "y" : 1055
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82111,
    "reactomeId" : 10660968,
    "displayName" : "Homologues of C3a",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 308,
      "y" : 1321
    },
    "minX" : 277,
    "maxX" : 340,
    "minY" : 1310,
    "maxY" : 1333,
    "prop" : {
      "x" : 277,
      "y" : 1310,
      "width" : 63,
      "height" : 23
    },
    "textPosition" : {
      "x" : 277,
      "y" : 1297
    },
    "connectors" : [ {
      "edgeId" : 82110,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82113,
    "reactomeId" : 10712916,
    "displayName" : "CPN, CBP2",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 378,
      "y" : 1273
    },
    "minX" : 343,
    "maxX" : 414,
    "minY" : 1262,
    "maxY" : 1313,
    "prop" : {
      "x" : 343,
      "y" : 1262,
      "width" : 71,
      "height" : 23
    },
    "textPosition" : {
      "x" : 358,
      "y" : 1256
    },
    "connectors" : [ {
      "edgeId" : 82110,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 378,
          "y" : 1291
        },
        "to" : {
          "x" : 378,
          "y" : 1305
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 378,
          "y" : 1309
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 378,
          "y" : 1309
        }
      }
    } ]
  }, {
    "id" : 82112,
    "reactomeId" : 10678909,
    "displayName" : "Homologues of C3a-desArg",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 474,
      "y" : 1322
    },
    "minX" : 415,
    "maxX" : 533,
    "minY" : 1304,
    "maxY" : 1341,
    "prop" : {
      "x" : 415,
      "y" : 1304,
      "width" : 118,
      "height" : 37
    },
    "textPosition" : {
      "x" : 421,
      "y" : 1305
    },
    "connectors" : [ {
      "edgeId" : 82110,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82115,
    "reactomeId" : 10661739,
    "displayName" : "C5",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2145,
      "y" : 56
    },
    "minX" : 2083,
    "maxX" : 2164,
    "minY" : 39,
    "maxY" : 81,
    "prop" : {
      "x" : 2133,
      "y" : 45,
      "width" : 25,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2133,
      "y" : 47
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2158,
          "y" : 45
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2158,
          "y" : 45
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82114,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2130,
          "y" : 61
        },
        "to" : {
          "x" : 2083,
          "y" : 81
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82117,
    "reactomeId" : 10722535,
    "displayName" : "C5:C5 inhibitors",
    "schemaClass" : "Complex",
    "renderableClass" : "ComplexDrug",
    "position" : {
      "x" : 2083,
      "y" : 135
    },
    "minX" : 2032,
    "maxX" : 2140,
    "minY" : 118,
    "maxY" : 147,
    "prop" : {
      "x" : 2032,
      "y" : 124,
      "width" : 102,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2050,
      "y" : 112
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2134,
          "y" : 124
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2134,
          "y" : 124
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82114,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82116,
    "reactomeId" : 9691614,
    "displayName" : "C5 inhibitors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySetDrug",
    "position" : {
      "x" : 2013,
      "y" : 46
    },
    "minX" : 1972,
    "maxX" : 2083,
    "minY" : 35,
    "maxY" : 81,
    "prop" : {
      "x" : 1972,
      "y" : 35,
      "width" : 82,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1980,
      "y" : 29
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 82114,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2036,
          "y" : 64
        },
        "to" : {
          "x" : 2083,
          "y" : 81
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82119,
    "reactomeId" : 9957061,
    "displayName" : "C3 inhibitors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySetDrug",
    "position" : {
      "x" : 465,
      "y" : 1388
    },
    "minX" : 424,
    "maxX" : 537,
    "minY" : 1377,
    "maxY" : 1420,
    "prop" : {
      "x" : 424,
      "y" : 1377,
      "width" : 82,
      "height" : 23
    },
    "textPosition" : {
      "x" : 432,
      "y" : 1371
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 82118,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 490,
          "y" : 1406
        },
        "to" : {
          "x" : 537,
          "y" : 1420
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82120,
    "reactomeId" : 10728172,
    "displayName" : "C3:C3 inhibitors",
    "schemaClass" : "Complex",
    "renderableClass" : "ComplexDrug",
    "position" : {
      "x" : 539,
      "y" : 1493
    },
    "minX" : 488,
    "maxX" : 596,
    "minY" : 1476,
    "maxY" : 1505,
    "prop" : {
      "x" : 488,
      "y" : 1482,
      "width" : 102,
      "height" : 23
    },
    "textPosition" : {
      "x" : 506,
      "y" : 1470
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 590,
          "y" : 1482
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 590,
          "y" : 1482
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82118,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82123,
    "reactomeId" : 9957436,
    "displayName" : "C5AR1 antagonists",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySetDrug",
    "position" : {
      "x" : 2409,
      "y" : 326
    },
    "minX" : 2350,
    "maxX" : 2468,
    "minY" : 315,
    "maxY" : 359,
    "prop" : {
      "x" : 2350,
      "y" : 315,
      "width" : 118,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2367,
      "y" : 309
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 82121,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2388,
          "y" : 344
        },
        "to" : {
          "x" : 2351,
          "y" : 359
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82122,
    "reactomeId" : 10669721,
    "displayName" : "c5ar1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2275,
      "y" : 275
    },
    "minX" : 2251,
    "maxX" : 2351,
    "minY" : 258,
    "maxY" : 359,
    "prop" : {
      "x" : 2251,
      "y" : 264,
      "width" : 49,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2253,
      "y" : 265
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2300,
          "y" : 264
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2300,
          "y" : 264
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82121,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2285,
          "y" : 290
        },
        "to" : {
          "x" : 2351,
          "y" : 359
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82124,
    "reactomeId" : 10728176,
    "displayName" : "C5AR1:C5AR1 antagonist",
    "schemaClass" : "Complex",
    "renderableClass" : "ComplexDrug",
    "position" : {
      "x" : 2284,
      "y" : 434
    },
    "minX" : 2236,
    "maxX" : 2339,
    "minY" : 410,
    "maxY" : 453,
    "prop" : {
      "x" : 2236,
      "y" : 416,
      "width" : 97,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2236,
      "y" : 418
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2333,
          "y" : 416
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2333,
          "y" : 416
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 82121,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 82127,
    "reactomeId" : 10661784,
    "displayName" : "C8",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2329,
      "y" : 514
    },
    "minX" : 2317,
    "maxX" : 2348,
    "minY" : 497,
    "maxY" : 526,
    "prop" : {
      "x" : 2317,
      "y" : 503,
      "width" : 25,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2317,
      "y" : 505
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2342,
          "y" : 503
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2342,
          "y" : 503
        }
      }
    },
    "connectors" : [ ]
  }, {
    "id" : 82130,
    "reactomeId" : 10679446,
    "displayName" : "C4bC2a, C3bBb",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 3703,
      "y" : 263
    },
    "minX" : 3652,
    "maxX" : 3755,
    "minY" : 252,
    "maxY" : 275,
    "prop" : {
      "x" : 3652,
      "y" : 252,
      "width" : 103,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3671,
      "y" : 246
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ ]
  } ],
  "edges" : [ {
    "id" : 82051,
    "reactomeId" : 10679473,
    "displayName" : "Factor H binds to membrane-associated C3b",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2751,
      "y" : 922
    },
    "minX" : 2724,
    "maxX" : 2757,
    "minY" : 804,
    "maxY" : 1073,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2749,
        "y" : 804
      },
      "to" : {
        "x" : 2751,
        "y" : 922
      }
    }, {
      "from" : {
        "x" : 2751,
        "y" : 922
      },
      "to" : {
        "x" : 2724,
        "y" : 1073
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2721,
        "y" : 1065
      },
      "b" : {
        "x" : 2724,
        "y" : 1073
      },
      "c" : {
        "x" : 2729,
        "y" : 1067
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2729,
        "y" : 1067
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2751,
        "y" : 922
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2751,
        "y" : 922
      }
    },
    "inputs" : [ {
      "id" : 82052,
      "points" : [ {
        "x" : 2629,
        "y" : 791
      } ]
    }, {
      "id" : 82053,
      "points" : [ {
        "x" : 2695,
        "y" : 764
      } ]
    } ],
    "outputs" : [ {
      "id" : 82054
    } ],
    "activators" : [ {
      "id" : 82055,
      "points" : [ {
        "x" : 3235,
        "y" : 1067
      } ]
    } ]
  }, {
    "id" : 82114,
    "reactomeId" : 10722537,
    "displayName" : "C5 binds C5 inhibitors",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2083,
      "y" : 101
    },
    "minX" : 2077,
    "maxX" : 2089,
    "minY" : 75,
    "maxY" : 121,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2083,
        "y" : 81
      },
      "to" : {
        "x" : 2083,
        "y" : 101
      }
    }, {
      "from" : {
        "x" : 2083,
        "y" : 101
      },
      "to" : {
        "x" : 2083,
        "y" : 121
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2079,
        "y" : 114
      },
      "b" : {
        "x" : 2083,
        "y" : 121
      },
      "c" : {
        "x" : 2087,
        "y" : 114
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2087,
        "y" : 114
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2083,
        "y" : 101
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2083,
        "y" : 101
      }
    },
    "inputs" : [ {
      "id" : 82115,
      "points" : [ {
        "x" : 2130,
        "y" : 61
      } ]
    }, {
      "id" : 82116,
      "points" : [ {
        "x" : 2036,
        "y" : 64
      } ]
    } ],
    "outputs" : [ {
      "id" : 82117
    } ]
  }, {
    "id" : 82118,
    "reactomeId" : 10728174,
    "displayName" : "C3 binds C3 inhibitors",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 537,
      "y" : 1444
    },
    "minX" : 531,
    "maxX" : 543,
    "minY" : 1420,
    "maxY" : 1479,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 537,
        "y" : 1420
      },
      "to" : {
        "x" : 537,
        "y" : 1444
      }
    }, {
      "from" : {
        "x" : 537,
        "y" : 1444
      },
      "to" : {
        "x" : 538,
        "y" : 1479
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 534,
        "y" : 1472
      },
      "b" : {
        "x" : 538,
        "y" : 1479
      },
      "c" : {
        "x" : 542,
        "y" : 1472
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 542,
        "y" : 1472
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 537,
        "y" : 1444
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 537,
        "y" : 1444
      }
    },
    "inputs" : [ {
      "id" : 81995,
      "points" : [ {
        "x" : 556,
        "y" : 1253
      } ]
    }, {
      "id" : 82119,
      "points" : [ {
        "x" : 490,
        "y" : 1406
      } ]
    } ],
    "outputs" : [ {
      "id" : 82120
    } ]
  }, {
    "id" : 81990,
    "reactomeId" : 10660934,
    "displayName" : "Formation of Classical C3 convertase (C4b:C2a complex)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1883,
      "y" : 198
    },
    "minX" : 1838,
    "maxX" : 1903,
    "minY" : 192,
    "maxY" : 222,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1838,
        "y" : 198
      },
      "to" : {
        "x" : 1883,
        "y" : 198
      }
    }, {
      "from" : {
        "x" : 1883,
        "y" : 198
      },
      "to" : {
        "x" : 1903,
        "y" : 222
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1895,
        "y" : 219
      },
      "b" : {
        "x" : 1903,
        "y" : 222
      },
      "c" : {
        "x" : 1902,
        "y" : 214
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1902,
        "y" : 214
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1883,
        "y" : 198
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1883,
        "y" : 198
      }
    },
    "inputs" : [ {
      "id" : 81991,
      "points" : [ {
        "x" : 1814,
        "y" : 222
      } ]
    }, {
      "id" : 81992,
      "points" : [ {
        "x" : 1768,
        "y" : 32
      } ]
    } ],
    "outputs" : [ {
      "id" : 81993
    } ]
  }, {
    "id" : 82121,
    "reactomeId" : 10728178,
    "displayName" : "C5AR1 binds C5AR1 antagonist",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2350,
      "y" : 395
    },
    "minX" : 2315,
    "maxX" : 2356,
    "minY" : 359,
    "maxY" : 413,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2351,
        "y" : 359
      },
      "to" : {
        "x" : 2350,
        "y" : 395
      }
    }, {
      "from" : {
        "x" : 2350,
        "y" : 395
      },
      "to" : {
        "x" : 2315,
        "y" : 413
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2319,
        "y" : 406
      },
      "b" : {
        "x" : 2315,
        "y" : 413
      },
      "c" : {
        "x" : 2323,
        "y" : 413
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2323,
        "y" : 413
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2350,
        "y" : 395
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2350,
        "y" : 395
      }
    },
    "inputs" : [ {
      "id" : 82122,
      "points" : [ {
        "x" : 2285,
        "y" : 290
      } ]
    }, {
      "id" : 82123,
      "points" : [ {
        "x" : 2388,
        "y" : 344
      } ]
    } ],
    "outputs" : [ {
      "id" : 82124
    } ]
  }, {
    "id" : 82056,
    "reactomeId" : 10679380,
    "displayName" : "Factor H binds to C3bBb",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2642,
      "y" : 921
    },
    "minX" : 2636,
    "maxX" : 2662,
    "minY" : 878,
    "maxY" : 964,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2644,
        "y" : 878
      },
      "to" : {
        "x" : 2642,
        "y" : 921
      }
    }, {
      "from" : {
        "x" : 2642,
        "y" : 921
      },
      "to" : {
        "x" : 2662,
        "y" : 964
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2655,
        "y" : 959
      },
      "b" : {
        "x" : 2662,
        "y" : 964
      },
      "c" : {
        "x" : 2663,
        "y" : 956
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2663,
        "y" : 956
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2642,
        "y" : 921
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2642,
        "y" : 921
      }
    },
    "inputs" : [ {
      "id" : 82052,
      "points" : [ {
        "x" : 2590,
        "y" : 806
      } ]
    }, {
      "id" : 82057,
      "points" : [ {
        "x" : 2669,
        "y" : 850
      } ]
    } ],
    "outputs" : [ {
      "id" : 82058
    } ],
    "activators" : [ {
      "id" : 82055,
      "points" : [ {
        "x" : 3227,
        "y" : 1067
      } ]
    } ]
  }, {
    "id" : 82059,
    "reactomeId" : 10679412,
    "displayName" : "Factor H displaces Bb",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2695,
      "y" : 1036
    },
    "minX" : 2679,
    "maxX" : 2711,
    "minY" : 1007,
    "maxY" : 1053,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 2679,
        "y" : 1007
      },
      "to" : {
        "x" : 2695,
        "y" : 1036
      }
    }, {
      "from" : {
        "x" : 2695,
        "y" : 1036
      },
      "to" : {
        "x" : 2711,
        "y" : 1053
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 2695,
        "y" : 1036
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 2695,
        "y" : 1036
      }
    },
    "inputs" : [ {
      "id" : 82058
    } ],
    "outputs" : [ {
      "id" : 82040,
      "points" : [ {
        "x" : 3154,
        "y" : 278
      } ]
    }, {
      "id" : 82054,
      "points" : [ {
        "x" : 2716,
        "y" : 1073
      } ]
    } ]
  }, {
    "id" : 81994,
    "reactomeId" : 10661788,
    "displayName" : "Spontaneous hydrolysis of C3 thioester",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 851,
      "y" : 1361
    },
    "minX" : 799,
    "maxX" : 1192,
    "minY" : 1355,
    "maxY" : 1367,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 799,
        "y" : 1361
      },
      "to" : {
        "x" : 851,
        "y" : 1361
      }
    }, {
      "from" : {
        "x" : 851,
        "y" : 1361
      },
      "to" : {
        "x" : 1192,
        "y" : 1361
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1185,
        "y" : 1365
      },
      "b" : {
        "x" : 1192,
        "y" : 1361
      },
      "c" : {
        "x" : 1185,
        "y" : 1357
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1185,
        "y" : 1357
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 851,
        "y" : 1361
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 851,
        "y" : 1361
      }
    },
    "inputs" : [ {
      "id" : 81995,
      "points" : [ {
        "x" : 580,
        "y" : 1253
      } ]
    }, {
      "id" : 81996,
      "points" : [ {
        "x" : 766,
        "y" : 1374
      } ]
    } ],
    "outputs" : [ {
      "id" : 81997
    } ]
  }, {
    "id" : 82060,
    "reactomeId" : 10679272,
    "displayName" : "Complement factor I complex formation",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3623,
      "y" : 1343
    },
    "minX" : 3479,
    "maxX" : 3689,
    "minY" : 1337,
    "maxY" : 1349,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3689,
        "y" : 1343
      },
      "to" : {
        "x" : 3623,
        "y" : 1343
      }
    }, {
      "from" : {
        "x" : 3623,
        "y" : 1343
      },
      "to" : {
        "x" : 3479,
        "y" : 1341
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3486,
        "y" : 1337
      },
      "b" : {
        "x" : 3479,
        "y" : 1341
      },
      "c" : {
        "x" : 3486,
        "y" : 1345
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3486,
        "y" : 1345
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3623,
        "y" : 1343
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3623,
        "y" : 1343
      }
    },
    "inputs" : [ {
      "id" : 82061,
      "points" : [ {
        "x" : 3739,
        "y" : 1327
      } ]
    }, {
      "id" : 82062,
      "points" : [ {
        "x" : 3731,
        "y" : 1353
      } ]
    } ],
    "outputs" : [ {
      "id" : 82063
    } ]
  }, {
    "id" : 81998,
    "reactomeId" : 10661794,
    "displayName" : "Factor B binds to C3(H2O)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1315,
      "y" : 1274
    },
    "minX" : 1282,
    "maxX" : 1357,
    "minY" : 1268,
    "maxY" : 1280,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1282,
        "y" : 1274
      },
      "to" : {
        "x" : 1315,
        "y" : 1274
      }
    }, {
      "from" : {
        "x" : 1315,
        "y" : 1274
      },
      "to" : {
        "x" : 1357,
        "y" : 1274
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1350,
        "y" : 1278
      },
      "b" : {
        "x" : 1357,
        "y" : 1274
      },
      "c" : {
        "x" : 1350,
        "y" : 1270
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1350,
        "y" : 1270
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1315,
        "y" : 1274
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1315,
        "y" : 1274
      }
    },
    "inputs" : [ {
      "id" : 81997,
      "points" : [ {
        "x" : 1231,
        "y" : 1347
      } ]
    }, {
      "id" : 81999,
      "points" : [ {
        "x" : 1226,
        "y" : 1219
      } ]
    } ],
    "outputs" : [ {
      "id" : 82000
    } ]
  }, {
    "id" : 82001,
    "reactomeId" : 10661809,
    "displayName" : "Factor D cleaves C3(H2O)-bound Factor B",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1513,
      "y" : 1274
    },
    "minX" : 1447,
    "maxX" : 1569,
    "minY" : 1268,
    "maxY" : 1280,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1447,
        "y" : 1274
      },
      "to" : {
        "x" : 1513,
        "y" : 1274
      }
    }, {
      "from" : {
        "x" : 1513,
        "y" : 1274
      },
      "to" : {
        "x" : 1569,
        "y" : 1275
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1507,
        "y" : 1268
      },
      "b" : {
        "x" : 1519,
        "y" : 1280
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1513,
        "y" : 1274
      }
    },
    "inputs" : [ {
      "id" : 82000
    } ],
    "outputs" : [ {
      "id" : 82002,
      "points" : [ {
        "x" : 1629,
        "y" : 1249
      } ]
    }, {
      "id" : 82003,
      "points" : [ {
        "x" : 1622,
        "y" : 1294
      } ]
    } ],
    "catalysts" : [ {
      "id" : 82004,
      "points" : [ {
        "x" : 1514,
        "y" : 1235
      } ]
    } ]
  }, {
    "id" : 82064,
    "reactomeId" : 10679274,
    "displayName" : "Complement factor I binds to extracellular Factor H:C3b",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3281,
      "y" : 1231
    },
    "minX" : 3240,
    "maxX" : 3307,
    "minY" : 1225,
    "maxY" : 1237,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3307,
        "y" : 1231
      },
      "to" : {
        "x" : 3281,
        "y" : 1231
      }
    }, {
      "from" : {
        "x" : 3281,
        "y" : 1231
      },
      "to" : {
        "x" : 3240,
        "y" : 1231
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3247,
        "y" : 1227
      },
      "b" : {
        "x" : 3240,
        "y" : 1231
      },
      "c" : {
        "x" : 3247,
        "y" : 1235
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3247,
        "y" : 1235
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3281,
        "y" : 1231
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3281,
        "y" : 1231
      }
    },
    "inputs" : [ {
      "id" : 82050,
      "points" : [ {
        "x" : 3286,
        "y" : 1171
      } ]
    }, {
      "id" : 82063,
      "points" : [ {
        "x" : 3447,
        "y" : 1331
      } ]
    } ],
    "outputs" : [ {
      "id" : 82065
    } ]
  }, {
    "id" : 82066,
    "reactomeId" : 10679374,
    "displayName" : "Complement factor I binds to membrane-associated Factor H:C3b",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2801,
      "y" : 1128
    },
    "minX" : 2773,
    "maxX" : 2837,
    "minY" : 1100,
    "maxY" : 1134,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2773,
        "y" : 1128
      },
      "to" : {
        "x" : 2801,
        "y" : 1128
      }
    }, {
      "from" : {
        "x" : 2801,
        "y" : 1128
      },
      "to" : {
        "x" : 2837,
        "y" : 1100
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2834,
        "y" : 1107
      },
      "b" : {
        "x" : 2837,
        "y" : 1100
      },
      "c" : {
        "x" : 2829,
        "y" : 1101
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2829,
        "y" : 1101
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2801,
        "y" : 1128
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2801,
        "y" : 1128
      }
    },
    "inputs" : [ {
      "id" : 82054,
      "points" : [ {
        "x" : 2749,
        "y" : 1116
      } ]
    }, {
      "id" : 82063,
      "points" : [ {
        "x" : 3447,
        "y" : 1341
      }, {
        "x" : 2883,
        "y" : 1341
      } ]
    } ],
    "outputs" : [ {
      "id" : 82067
    } ]
  }, {
    "id" : 82005,
    "reactomeId" : 10661811,
    "displayName" : "Properdin stabilizes C3b:Bb bound to cell surfaces",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1817,
      "y" : 1158
    },
    "minX" : 1753,
    "maxX" : 1899,
    "minY" : 1147,
    "maxY" : 1164,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1753,
        "y" : 1158
      },
      "to" : {
        "x" : 1817,
        "y" : 1158
      }
    }, {
      "from" : {
        "x" : 1817,
        "y" : 1158
      },
      "to" : {
        "x" : 1899,
        "y" : 1147
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1893,
        "y" : 1152
      },
      "b" : {
        "x" : 1899,
        "y" : 1147
      },
      "c" : {
        "x" : 1892,
        "y" : 1144
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1892,
        "y" : 1144
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1817,
        "y" : 1158
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1817,
        "y" : 1158
      }
    },
    "inputs" : [ {
      "id" : 82006,
      "points" : [ {
        "x" : 1714,
        "y" : 1152
      } ]
    }, {
      "id" : 82007,
      "points" : [ {
        "x" : 1744,
        "y" : 1176
      } ]
    } ],
    "outputs" : [ {
      "id" : 82008
    } ]
  }, {
    "id" : 82068,
    "reactomeId" : 10679410,
    "displayName" : "Factor I inactivates Factor H-boundC3b",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2936,
      "y" : 1086
    },
    "minX" : 2912,
    "maxX" : 2955,
    "minY" : 1080,
    "maxY" : 1092,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2912,
        "y" : 1085
      },
      "to" : {
        "x" : 2936,
        "y" : 1086
      }
    }, {
      "from" : {
        "x" : 2936,
        "y" : 1086
      },
      "to" : {
        "x" : 2955,
        "y" : 1085
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2930,
        "y" : 1080
      },
      "b" : {
        "x" : 2942,
        "y" : 1092
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2936,
        "y" : 1086
      }
    },
    "inputs" : [ {
      "id" : 82067
    } ],
    "outputs" : [ {
      "id" : 82069,
      "points" : [ {
        "x" : 2971,
        "y" : 1085
      } ]
    }, {
      "id" : 82070,
      "points" : [ {
        "x" : 3002,
        "y" : 1130
      } ]
    } ],
    "catalysts" : [ {
      "id" : 82067,
      "points" : [ {
        "x" : 2878,
        "y" : 1100
      }, {
        "x" : 2936,
        "y" : 1121
      } ]
    } ]
  }, {
    "id" : 82071,
    "reactomeId" : 10680486,
    "displayName" : "Factor H binds host cell surface markers",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3228,
      "y" : 1114
    },
    "minX" : 3176,
    "maxX" : 3257,
    "minY" : 1096,
    "maxY" : 1120,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3176,
        "y" : 1115
      },
      "to" : {
        "x" : 3228,
        "y" : 1114
      }
    }, {
      "from" : {
        "x" : 3228,
        "y" : 1114
      },
      "to" : {
        "x" : 3257,
        "y" : 1096
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3253,
        "y" : 1103
      },
      "b" : {
        "x" : 3257,
        "y" : 1096
      },
      "c" : {
        "x" : 3249,
        "y" : 1096
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3249,
        "y" : 1096
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3228,
        "y" : 1114
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3228,
        "y" : 1114
      }
    },
    "inputs" : [ {
      "id" : 82049,
      "points" : [ {
        "x" : 3142,
        "y" : 1128
      } ]
    }, {
      "id" : 82072,
      "points" : [ {
        "x" : 3163,
        "y" : 1098
      } ]
    } ],
    "outputs" : [ {
      "id" : 82055
    } ]
  }, {
    "id" : 82009,
    "reactomeId" : 10662097,
    "displayName" : "Formation of alternative pathway C5 convertase",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2074,
      "y" : 1169
    },
    "minX" : 2039,
    "maxX" : 2108,
    "minY" : 1163,
    "maxY" : 1175,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2039,
        "y" : 1169
      },
      "to" : {
        "x" : 2074,
        "y" : 1169
      }
    }, {
      "from" : {
        "x" : 2074,
        "y" : 1169
      },
      "to" : {
        "x" : 2108,
        "y" : 1169
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2068,
        "y" : 1163
      },
      "b" : {
        "x" : 2080,
        "y" : 1175
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2074,
        "y" : 1169
      }
    },
    "inputs" : [ {
      "id" : 82008,
      "points" : [ {
        "x" : 2012,
        "y" : 1162
      } ]
    }, {
      "id" : 81995,
      "points" : [ {
        "x" : 562,
        "y" : 1253
      }, {
        "x" : 638,
        "y" : 1426
      }, {
        "x" : 2018,
        "y" : 1420
      } ]
    } ],
    "outputs" : [ {
      "id" : 82010,
      "points" : [ {
        "x" : 2133,
        "y" : 1161
      } ]
    }, {
      "id" : 82011,
      "points" : [ {
        "x" : 2136,
        "y" : 1192
      } ]
    } ],
    "catalysts" : [ {
      "id" : 82008,
      "points" : [ {
        "x" : 2032,
        "y" : 1137
      }, {
        "x" : 2072,
        "y" : 1136
      } ]
    } ]
  }, {
    "id" : 82073,
    "reactomeId" : 10691864,
    "displayName" : "Ficolin-1 binds to molecular patterns on the target cell surface",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 151,
      "y" : 786
    },
    "minX" : 145,
    "maxX" : 177,
    "minY" : 766,
    "maxY" : 794,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 151,
        "y" : 766
      },
      "to" : {
        "x" : 151,
        "y" : 786
      }
    }, {
      "from" : {
        "x" : 151,
        "y" : 786
      },
      "to" : {
        "x" : 177,
        "y" : 794
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 169,
        "y" : 796
      },
      "b" : {
        "x" : 177,
        "y" : 794
      },
      "c" : {
        "x" : 172,
        "y" : 788
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 172,
        "y" : 788
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 151,
        "y" : 786
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 151,
        "y" : 786
      }
    },
    "inputs" : [ {
      "id" : 82074,
      "points" : [ {
        "x" : 118,
        "y" : 760
      } ]
    }, {
      "id" : 82075,
      "points" : [ {
        "x" : 184,
        "y" : 758
      } ]
    }, {
      "id" : 82076,
      "points" : [ {
        "x" : 152,
        "y" : 730
      } ],
      "stoichiometry" : 4
    } ],
    "outputs" : [ {
      "id" : 82077
    } ]
  }, {
    "id" : 82012,
    "reactomeId" : 10661005,
    "displayName" : "Cleavage of C3 by C3 convertases",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 689,
      "y" : 1218
    },
    "minX" : 627,
    "maxX" : 730,
    "minY" : 1212,
    "maxY" : 1228,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 627,
        "y" : 1228
      },
      "to" : {
        "x" : 689,
        "y" : 1218
      }
    }, {
      "from" : {
        "x" : 689,
        "y" : 1218
      },
      "to" : {
        "x" : 730,
        "y" : 1218
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 683,
        "y" : 1212
      },
      "b" : {
        "x" : 695,
        "y" : 1224
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 689,
        "y" : 1218
      }
    },
    "inputs" : [ {
      "id" : 81995
    } ],
    "outputs" : [ {
      "id" : 82013,
      "points" : [ {
        "x" : 822,
        "y" : 1203
      } ]
    }, {
      "id" : 82014,
      "points" : [ {
        "x" : 816,
        "y" : 1250
      } ]
    } ],
    "catalysts" : [ {
      "id" : 82015,
      "points" : [ {
        "x" : 690,
        "y" : 1158
      }, {
        "x" : 688,
        "y" : 1194
      } ]
    } ]
  }, {
    "id" : 82078,
    "reactomeId" : 10691838,
    "displayName" : "Ficolin-2 binds to molecular patterns on the target cell surface",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 147,
      "y" : 938
    },
    "minX" : 141,
    "maxX" : 174,
    "minY" : 919,
    "maxY" : 944,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 148,
        "y" : 919
      },
      "to" : {
        "x" : 147,
        "y" : 938
      }
    }, {
      "from" : {
        "x" : 147,
        "y" : 938
      },
      "to" : {
        "x" : 174,
        "y" : 941
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 167,
        "y" : 944
      },
      "b" : {
        "x" : 174,
        "y" : 941
      },
      "c" : {
        "x" : 168,
        "y" : 936
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 168,
        "y" : 936
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 147,
        "y" : 938
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 147,
        "y" : 938
      }
    },
    "inputs" : [ {
      "id" : 82079,
      "points" : [ {
        "x" : 200,
        "y" : 909
      } ]
    }, {
      "id" : 82080,
      "points" : [ {
        "x" : 117,
        "y" : 912
      } ]
    }, {
      "id" : 82081,
      "points" : [ {
        "x" : 148,
        "y" : 889
      } ],
      "stoichiometry" : 4
    } ],
    "outputs" : [ {
      "id" : 82082
    } ]
  }, {
    "id" : 82017,
    "reactomeId" : 10662857,
    "displayName" : "Factor B binds to surface-associated C3b",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1324,
      "y" : 1176
    },
    "minX" : 1290,
    "maxX" : 1359,
    "minY" : 1162,
    "maxY" : 1182,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1290,
        "y" : 1176
      },
      "to" : {
        "x" : 1324,
        "y" : 1176
      }
    }, {
      "from" : {
        "x" : 1324,
        "y" : 1176
      },
      "to" : {
        "x" : 1359,
        "y" : 1162
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1354,
        "y" : 1168
      },
      "b" : {
        "x" : 1359,
        "y" : 1162
      },
      "c" : {
        "x" : 1351,
        "y" : 1161
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1351,
        "y" : 1161
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1324,
        "y" : 1176
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1324,
        "y" : 1176
      }
    },
    "inputs" : [ {
      "id" : 82018,
      "points" : [ {
        "x" : 1246,
        "y" : 1163
      } ]
    }, {
      "id" : 81999,
      "points" : [ {
        "x" : 1246,
        "y" : 1190
      } ]
    } ],
    "outputs" : [ {
      "id" : 82019
    } ]
  }, {
    "id" : 82016,
    "reactomeId" : 10662860,
    "displayName" : "C3(H2O):Factor Bb cleaves C3 to C3b and C3a",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 688,
      "y" : 1247
    },
    "minX" : 627,
    "maxX" : 735,
    "minY" : 1241,
    "maxY" : 1253,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 627,
        "y" : 1242
      },
      "to" : {
        "x" : 688,
        "y" : 1247
      }
    }, {
      "from" : {
        "x" : 688,
        "y" : 1247
      },
      "to" : {
        "x" : 735,
        "y" : 1247
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 682,
        "y" : 1241
      },
      "b" : {
        "x" : 694,
        "y" : 1253
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 688,
        "y" : 1247
      }
    },
    "inputs" : [ {
      "id" : 81995
    } ],
    "outputs" : [ {
      "id" : 82013,
      "points" : [ {
        "x" : 822,
        "y" : 1207
      } ]
    }, {
      "id" : 82014,
      "points" : [ {
        "x" : 816,
        "y" : 1255
      } ]
    } ],
    "catalysts" : [ {
      "id" : 82003,
      "points" : [ {
        "x" : 1609,
        "y" : 1307
      }, {
        "x" : 690,
        "y" : 1290
      } ]
    } ]
  }, {
    "id" : 82083,
    "reactomeId" : 10691852,
    "displayName" : "Ficolin-3 binds to molecular patterns on the target cell surface",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 163,
      "y" : 1083
    },
    "minX" : 157,
    "maxX" : 180,
    "minY" : 1061,
    "maxY" : 1089,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 163,
        "y" : 1061
      },
      "to" : {
        "x" : 163,
        "y" : 1083
      }
    }, {
      "from" : {
        "x" : 163,
        "y" : 1083
      },
      "to" : {
        "x" : 180,
        "y" : 1087
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 172,
        "y" : 1089
      },
      "b" : {
        "x" : 180,
        "y" : 1087
      },
      "c" : {
        "x" : 174,
        "y" : 1082
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 174,
        "y" : 1082
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 163,
        "y" : 1083
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 163,
        "y" : 1083
      }
    },
    "inputs" : [ {
      "id" : 82084,
      "points" : [ {
        "x" : 192,
        "y" : 1052
      } ]
    }, {
      "id" : 82085,
      "points" : [ {
        "x" : 122,
        "y" : 1056
      } ]
    }, {
      "id" : 82086,
      "points" : [ {
        "x" : 162,
        "y" : 1033
      } ],
      "stoichiometry" : 4
    } ],
    "outputs" : [ {
      "id" : 82087
    } ]
  }, {
    "id" : 82021,
    "reactomeId" : 10661733,
    "displayName" : "Formation of classic pathway C5 convertase",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2062,
      "y" : 199
    },
    "minX" : 2035,
    "maxX" : 2100,
    "minY" : 193,
    "maxY" : 224,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2035,
        "y" : 199
      },
      "to" : {
        "x" : 2062,
        "y" : 199
      }
    }, {
      "from" : {
        "x" : 2062,
        "y" : 199
      },
      "to" : {
        "x" : 2100,
        "y" : 224
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2092,
        "y" : 224
      },
      "b" : {
        "x" : 2100,
        "y" : 224
      },
      "c" : {
        "x" : 2096,
        "y" : 217
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2096,
        "y" : 217
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2062,
        "y" : 199
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2062,
        "y" : 199
      }
    },
    "inputs" : [ {
      "id" : 81993,
      "points" : [ {
        "x" : 1950,
        "y" : 222
      } ]
    }, {
      "id" : 82022,
      "points" : [ {
        "x" : 2023,
        "y" : 224
      } ]
    } ],
    "outputs" : [ {
      "id" : 82023
    } ]
  }, {
    "id" : 82020,
    "reactomeId" : 10662855,
    "displayName" : "Factor D cleaves C3b-bound Factor B",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1525,
      "y" : 1163
    },
    "minX" : 1450,
    "maxX" : 1612,
    "minY" : 1154,
    "maxY" : 1178,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1450,
        "y" : 1154
      },
      "to" : {
        "x" : 1525,
        "y" : 1163
      }
    }, {
      "from" : {
        "x" : 1525,
        "y" : 1163
      },
      "to" : {
        "x" : 1612,
        "y" : 1178
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1519,
        "y" : 1157
      },
      "b" : {
        "x" : 1531,
        "y" : 1169
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1525,
        "y" : 1163
      }
    },
    "inputs" : [ {
      "id" : 82019
    } ],
    "outputs" : [ {
      "id" : 82002,
      "points" : [ {
        "x" : 1644,
        "y" : 1220
      } ]
    }, {
      "id" : 82006,
      "points" : [ {
        "x" : 1636,
        "y" : 1160
      } ]
    } ],
    "catalysts" : [ {
      "id" : 82004,
      "points" : [ {
        "x" : 1518,
        "y" : 1186
      } ]
    } ]
  }, {
    "id" : 82088,
    "reactomeId" : 10679268,
    "displayName" : "Factor I inactivates plasma Factor H-bound C3b",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3103,
      "y" : 1229
    },
    "minX" : 3076,
    "maxX" : 3153,
    "minY" : 1223,
    "maxY" : 1235,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3153,
        "y" : 1230
      },
      "to" : {
        "x" : 3103,
        "y" : 1229
      }
    }, {
      "from" : {
        "x" : 3103,
        "y" : 1229
      },
      "to" : {
        "x" : 3076,
        "y" : 1229
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3097,
        "y" : 1223
      },
      "b" : {
        "x" : 3109,
        "y" : 1235
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3103,
        "y" : 1229
      }
    },
    "inputs" : [ {
      "id" : 82065
    } ],
    "outputs" : [ {
      "id" : 82070,
      "points" : [ {
        "x" : 3022,
        "y" : 1159
      } ]
    }, {
      "id" : 82063,
      "points" : [ {
        "x" : 3447,
        "y" : 1339
      }, {
        "x" : 3086,
        "y" : 1304
      } ]
    }, {
      "id" : 82049,
      "points" : [ {
        "x" : 3117,
        "y" : 1149
      } ]
    }, {
      "id" : 82089,
      "points" : [ {
        "x" : 3039,
        "y" : 1252
      } ]
    } ],
    "catalysts" : [ {
      "id" : 82065,
      "points" : [ {
        "x" : 3166,
        "y" : 1246
      }, {
        "x" : 3107,
        "y" : 1266
      } ]
    } ]
  }, {
    "id" : 82024,
    "reactomeId" : 10661751,
    "displayName" : "C5b binds C6",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2521,
      "y" : 121
    },
    "minX" : 2515,
    "maxX" : 2529,
    "minY" : 115,
    "maxY" : 149,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2522,
        "y" : 121
      },
      "to" : {
        "x" : 2521,
        "y" : 121
      }
    }, {
      "from" : {
        "x" : 2521,
        "y" : 121
      },
      "to" : {
        "x" : 2529,
        "y" : 149
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2523,
        "y" : 143
      },
      "b" : {
        "x" : 2529,
        "y" : 149
      },
      "c" : {
        "x" : 2531,
        "y" : 141
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2531,
        "y" : 141
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2521,
        "y" : 121
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2521,
        "y" : 121
      }
    },
    "inputs" : [ {
      "id" : 82025,
      "points" : [ {
        "x" : 2502,
        "y" : 100
      } ]
    }, {
      "id" : 82026,
      "points" : [ {
        "x" : 2472,
        "y" : 127
      } ]
    } ],
    "outputs" : [ {
      "id" : 82027
    } ]
  }, {
    "id" : 82090,
    "reactomeId" : 10691135,
    "displayName" : "Vitronectin (VTN) binds to C5b:C6:C7",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2508,
      "y" : 383
    },
    "minX" : 2502,
    "maxX" : 2514,
    "minY" : 356,
    "maxY" : 417,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2508,
        "y" : 356
      },
      "to" : {
        "x" : 2508,
        "y" : 383
      }
    }, {
      "from" : {
        "x" : 2508,
        "y" : 383
      },
      "to" : {
        "x" : 2508,
        "y" : 417
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2504,
        "y" : 410
      },
      "b" : {
        "x" : 2508,
        "y" : 417
      },
      "c" : {
        "x" : 2512,
        "y" : 410
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2512,
        "y" : 410
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2508,
        "y" : 383
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2508,
        "y" : 383
      }
    },
    "inputs" : [ {
      "id" : 82091,
      "points" : [ {
        "x" : 2528,
        "y" : 342
      } ]
    }, {
      "id" : 82030,
      "points" : [ {
        "x" : 2500,
        "y" : 308
      } ]
    } ],
    "outputs" : [ {
      "id" : 82092
    } ]
  }, {
    "id" : 82093,
    "reactomeId" : 10691812,
    "displayName" : "Hydrolysis of internal thioester in C4b",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 4672,
      "y" : 868
    },
    "minX" : 4666,
    "maxX" : 4678,
    "minY" : 836,
    "maxY" : 897,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 4671,
        "y" : 836
      },
      "to" : {
        "x" : 4672,
        "y" : 868
      }
    }, {
      "from" : {
        "x" : 4672,
        "y" : 868
      },
      "to" : {
        "x" : 4673,
        "y" : 897
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 4669,
        "y" : 890
      },
      "b" : {
        "x" : 4673,
        "y" : 897
      },
      "c" : {
        "x" : 4677,
        "y" : 890
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 4677,
        "y" : 890
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 4672,
        "y" : 868
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 4672,
        "y" : 868
      }
    },
    "inputs" : [ {
      "id" : 82094,
      "points" : [ {
        "x" : 4687,
        "y" : 825
      } ]
    }, {
      "id" : 82095,
      "points" : [ {
        "x" : 4629,
        "y" : 803
      } ]
    } ],
    "outputs" : [ {
      "id" : 82096
    } ]
  }, {
    "id" : 82028,
    "reactomeId" : 10661769,
    "displayName" : "C7 binds C5b:C6",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2495,
      "y" : 219
    },
    "minX" : 2489,
    "maxX" : 2501,
    "minY" : 193,
    "maxY" : 279,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2495,
        "y" : 193
      },
      "to" : {
        "x" : 2495,
        "y" : 219
      }
    }, {
      "from" : {
        "x" : 2495,
        "y" : 219
      },
      "to" : {
        "x" : 2498,
        "y" : 279
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2494,
        "y" : 272
      },
      "b" : {
        "x" : 2498,
        "y" : 279
      },
      "c" : {
        "x" : 2502,
        "y" : 272
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2502,
        "y" : 272
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2495,
        "y" : 219
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2495,
        "y" : 219
      }
    },
    "inputs" : [ {
      "id" : 82027,
      "points" : [ {
        "x" : 2518,
        "y" : 178
      } ]
    }, {
      "id" : 82029,
      "points" : [ {
        "x" : 2476,
        "y" : 180
      } ]
    } ],
    "outputs" : [ {
      "id" : 82030
    } ],
    "inhibitors" : [ {
      "id" : 82031,
      "points" : [ {
        "x" : 2579,
        "y" : 600
      }, {
        "x" : 2657,
        "y" : 527
      }, {
        "x" : 2658,
        "y" : 274
      } ]
    } ]
  }, {
    "id" : 82033,
    "reactomeId" : 10679471,
    "displayName" : "C4b binds to cell surface",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1774,
      "y" : 200
    },
    "minX" : 1727,
    "maxX" : 1794,
    "minY" : 194,
    "maxY" : 222,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1727,
        "y" : 198
      },
      "to" : {
        "x" : 1774,
        "y" : 200
      }
    }, {
      "from" : {
        "x" : 1774,
        "y" : 200
      },
      "to" : {
        "x" : 1794,
        "y" : 222
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1786,
        "y" : 220
      },
      "b" : {
        "x" : 1794,
        "y" : 222
      },
      "c" : {
        "x" : 1792,
        "y" : 214
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1792,
        "y" : 214
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1774,
        "y" : 200
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1774,
        "y" : 200
      }
    },
    "inputs" : [ {
      "id" : 82034,
      "points" : [ {
        "x" : 1710,
        "y" : 125
      } ]
    }, {
      "id" : 82035,
      "points" : [ {
        "x" : 1701,
        "y" : 222
      } ]
    } ],
    "outputs" : [ {
      "id" : 81991
    } ]
  }, {
    "id" : 82097,
    "reactomeId" : 10675315,
    "displayName" : "C3a receptor binds anaphylatoxin C3a",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 898,
      "y" : 1169
    },
    "minX" : 864,
    "maxX" : 934,
    "minY" : 1157,
    "maxY" : 1175,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 864,
        "y" : 1170
      },
      "to" : {
        "x" : 898,
        "y" : 1169
      }
    }, {
      "from" : {
        "x" : 898,
        "y" : 1169
      },
      "to" : {
        "x" : 934,
        "y" : 1157
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 929,
        "y" : 1163
      },
      "b" : {
        "x" : 934,
        "y" : 1157
      },
      "c" : {
        "x" : 926,
        "y" : 1155
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 926,
        "y" : 1155
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 898,
        "y" : 1169
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 898,
        "y" : 1169
      }
    },
    "inputs" : [ {
      "id" : 82013,
      "points" : [ {
        "x" : 849,
        "y" : 1187
      } ]
    }, {
      "id" : 82098,
      "points" : [ {
        "x" : 851,
        "y" : 1158
      } ]
    } ],
    "outputs" : [ {
      "id" : 82099
    } ]
  }, {
    "id" : 82032,
    "reactomeId" : 10661772,
    "displayName" : "C5b:C6:C7 translocates to the plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2428,
      "y" : 472
    },
    "minX" : 2314,
    "maxX" : 2494,
    "minY" : 308,
    "maxY" : 478,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2494,
        "y" : 308
      },
      "to" : {
        "x" : 2428,
        "y" : 472
      }
    }, {
      "from" : {
        "x" : 2428,
        "y" : 472
      },
      "to" : {
        "x" : 2314,
        "y" : 478
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2422,
        "y" : 466
      },
      "b" : {
        "x" : 2434,
        "y" : 478
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2428,
        "y" : 472
      }
    },
    "inputs" : [ {
      "id" : 82030
    } ],
    "inhibitors" : [ {
      "id" : 82031,
      "points" : [ {
        "x" : 2544,
        "y" : 600
      } ]
    } ]
  }, {
    "id" : 82100,
    "reactomeId" : 10678917,
    "displayName" : "C5AR2 binds anaphylatoxins and thier desArginated derivatives",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 468,
      "y" : 1164
    },
    "minX" : 433,
    "maxX" : 503,
    "minY" : 1155,
    "maxY" : 1170,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 433,
        "y" : 1164
      },
      "to" : {
        "x" : 468,
        "y" : 1164
      }
    }, {
      "from" : {
        "x" : 468,
        "y" : 1164
      },
      "to" : {
        "x" : 503,
        "y" : 1155
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 497,
        "y" : 1161
      },
      "b" : {
        "x" : 503,
        "y" : 1155
      },
      "c" : {
        "x" : 495,
        "y" : 1153
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 495,
        "y" : 1153
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 468,
        "y" : 1164
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 468,
        "y" : 1164
      }
    },
    "inputs" : [ {
      "id" : 82101,
      "points" : [ {
        "x" : 406,
        "y" : 1154
      } ]
    }, {
      "id" : 82102,
      "points" : [ {
        "x" : 403,
        "y" : 1183
      } ]
    } ],
    "outputs" : [ {
      "id" : 82103
    } ]
  }, {
    "id" : 82036,
    "reactomeId" : 10679448,
    "displayName" : "C3b binds to cell surface",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1141,
      "y" : 1186
    },
    "minX" : 1090,
    "maxX" : 1193,
    "minY" : 1163,
    "maxY" : 1192,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1090,
        "y" : 1187
      },
      "to" : {
        "x" : 1141,
        "y" : 1186
      }
    }, {
      "from" : {
        "x" : 1141,
        "y" : 1186
      },
      "to" : {
        "x" : 1193,
        "y" : 1163
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1188,
        "y" : 1169
      },
      "b" : {
        "x" : 1193,
        "y" : 1163
      },
      "c" : {
        "x" : 1185,
        "y" : 1162
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1185,
        "y" : 1162
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1141,
        "y" : 1186
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1141,
        "y" : 1186
      }
    },
    "inputs" : [ {
      "id" : 82014,
      "points" : [ {
        "x" : 855,
        "y" : 1252
      } ]
    }, {
      "id" : 82037,
      "points" : [ {
        "x" : 1081,
        "y" : 1157
      } ]
    } ],
    "outputs" : [ {
      "id" : 82018
    } ]
  }, {
    "id" : 82038,
    "reactomeId" : 10679450,
    "displayName" : "C3 convertases spontaneously dissociate",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2824,
      "y" : 206
    },
    "minX" : 2748,
    "maxX" : 2856,
    "minY" : 200,
    "maxY" : 246,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2748,
        "y" : 246
      },
      "to" : {
        "x" : 2824,
        "y" : 206
      }
    }, {
      "from" : {
        "x" : 2824,
        "y" : 206
      },
      "to" : {
        "x" : 2856,
        "y" : 208
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2818,
        "y" : 200
      },
      "b" : {
        "x" : 2830,
        "y" : 212
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2824,
        "y" : 206
      }
    },
    "inputs" : [ {
      "id" : 82039
    } ],
    "outputs" : [ {
      "id" : 82040,
      "points" : [ {
        "x" : 3112,
        "y" : 254
      } ],
      "stoichiometry" : 3
    }, {
      "id" : 82041,
      "points" : [ {
        "x" : 2882,
        "y" : 178
      } ]
    }, {
      "id" : 82042,
      "points" : [ {
        "x" : 2999,
        "y" : 255
      } ]
    }, {
      "id" : 82043,
      "points" : [ {
        "x" : 2869,
        "y" : 254
      } ]
    }, {
      "id" : 82044,
      "points" : [ {
        "x" : 2936,
        "y" : 177
      } ]
    }, {
      "id" : 82045,
      "points" : [ {
        "x" : 3066,
        "y" : 206
      } ],
      "stoichiometry" : 3
    }, {
      "id" : 82046,
      "points" : [ {
        "x" : 3024,
        "y" : 173
      } ]
    } ]
  }, {
    "id" : 82104,
    "reactomeId" : 10712894,
    "displayName" : "Clusterin binds C5b-C7, C8, C9",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2559,
      "y" : 568
    },
    "minX" : 2553,
    "maxX" : 2565,
    "minY" : 530,
    "maxY" : 600,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2561,
        "y" : 530
      },
      "to" : {
        "x" : 2559,
        "y" : 568
      }
    }, {
      "from" : {
        "x" : 2559,
        "y" : 568
      },
      "to" : {
        "x" : 2560,
        "y" : 600
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2556,
        "y" : 593
      },
      "b" : {
        "x" : 2560,
        "y" : 600
      },
      "c" : {
        "x" : 2564,
        "y" : 593
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2564,
        "y" : 593
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2559,
        "y" : 568
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2559,
        "y" : 568
      }
    },
    "inputs" : [ {
      "id" : 82105,
      "points" : [ {
        "x" : 2601,
        "y" : 497
      } ]
    }, {
      "id" : 82106,
      "points" : [ {
        "x" : 2539,
        "y" : 506
      } ]
    } ],
    "outputs" : [ {
      "id" : 82031
    } ]
  }, {
    "id" : 82107,
    "reactomeId" : 10712516,
    "displayName" : "CFHR dimers bind C3b",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2312,
      "y" : 1087
    },
    "minX" : 2297,
    "maxX" : 2318,
    "minY" : 1055,
    "maxY" : 1117,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2313,
        "y" : 1055
      },
      "to" : {
        "x" : 2312,
        "y" : 1087
      }
    }, {
      "from" : {
        "x" : 2312,
        "y" : 1087
      },
      "to" : {
        "x" : 2297,
        "y" : 1117
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2297,
        "y" : 1109
      },
      "b" : {
        "x" : 2297,
        "y" : 1117
      },
      "c" : {
        "x" : 2304,
        "y" : 1113
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2304,
        "y" : 1113
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2312,
        "y" : 1087
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2312,
        "y" : 1087
      }
    },
    "inputs" : [ {
      "id" : 82018,
      "points" : [ {
        "x" : 1242,
        "y" : 1134
      }, {
        "x" : 1431,
        "y" : 1056
      } ]
    }, {
      "id" : 82108,
      "points" : [ {
        "x" : 2335,
        "y" : 1024
      } ]
    } ],
    "outputs" : [ {
      "id" : 82109
    } ]
  }, {
    "id" : 82047,
    "reactomeId" : 10679270,
    "displayName" : "Factor H binds to C3b",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3208,
      "y" : 1155
    },
    "minX" : 3174,
    "maxX" : 3250,
    "minY" : 1149,
    "maxY" : 1161,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3174,
        "y" : 1155
      },
      "to" : {
        "x" : 3208,
        "y" : 1155
      }
    }, {
      "from" : {
        "x" : 3208,
        "y" : 1155
      },
      "to" : {
        "x" : 3250,
        "y" : 1155
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3243,
        "y" : 1159
      },
      "b" : {
        "x" : 3250,
        "y" : 1155
      },
      "c" : {
        "x" : 3243,
        "y" : 1151
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3243,
        "y" : 1151
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3208,
        "y" : 1155
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3208,
        "y" : 1155
      }
    },
    "inputs" : [ {
      "id" : 82048,
      "points" : [ {
        "x" : 3154,
        "y" : 1167
      } ]
    }, {
      "id" : 82049,
      "points" : [ {
        "x" : 3142,
        "y" : 1140
      } ]
    } ],
    "outputs" : [ {
      "id" : 82050
    } ]
  }, {
    "id" : 82110,
    "reactomeId" : 10712919,
    "displayName" : "CPN, CPB2 cleave C3a, C5a",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 378,
      "y" : 1321
    },
    "minX" : 346,
    "maxX" : 409,
    "minY" : 1315,
    "maxY" : 1327,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 346,
        "y" : 1321
      },
      "to" : {
        "x" : 378,
        "y" : 1321
      }
    }, {
      "from" : {
        "x" : 378,
        "y" : 1321
      },
      "to" : {
        "x" : 409,
        "y" : 1321
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 402,
        "y" : 1325
      },
      "b" : {
        "x" : 409,
        "y" : 1321
      },
      "c" : {
        "x" : 402,
        "y" : 1317
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 402,
        "y" : 1317
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 372,
        "y" : 1315
      },
      "b" : {
        "x" : 384,
        "y" : 1327
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 378,
        "y" : 1321
      }
    },
    "inputs" : [ {
      "id" : 82111
    } ],
    "outputs" : [ {
      "id" : 82112
    } ],
    "catalysts" : [ {
      "id" : 82113,
      "points" : [ {
        "x" : 378,
        "y" : 1291
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 82129,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1256,
      "y" : 689
    },
    "minX" : 230,
    "maxX" : 2283,
    "minY" : 231,
    "maxY" : 1147,
    "prop" : {
      "x" : 230,
      "y" : 231,
      "width" : 2053,
      "height" : 916
    },
    "textPosition" : {
      "x" : 747,
      "y" : 477
    },
    "insets" : {
      "x" : 240,
      "y" : 241,
      "width" : 2033,
      "height" : 896
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 82075, 82162, 82163, 82082, 82164, 82079, 82087, 82167, 82084, 82165, 82166, 82158, 82077, 82157, 82160, 81993, 82023, 81991, 82035, 82022, 82151, 82152, 82155, 82156, 82019, 82006, 82015, 82018, 82037, 82154, 82008, 82010, 82141, 82099, 82098, 82103, 82101, 82122, 82173, 82174, 82175, 82176, 82124, 82109 ]
  }, {
    "id" : 82139,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 3593,
      "y" : 671
    },
    "minX" : 2673,
    "maxX" : 4514,
    "minY" : 250,
    "maxY" : 1092,
    "prop" : {
      "x" : 2673,
      "y" : 250,
      "width" : 1841,
      "height" : 842
    },
    "textPosition" : {
      "x" : 2849,
      "y" : 387
    },
    "insets" : {
      "x" : 2683,
      "y" : 260,
      "width" : 1821,
      "height" : 822
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 82058, 82057, 82053, 82055, 82059, 82072, 82142, 82148, 82149, 82150, 82130, 82040, 82039, 82042, 82043, 82051, 82054, 82067, 82068, 82069, 82172, 82171, 82177 ]
  } ],
  "notes" : [ {
    "id" : 82141,
    "displayName" : "Target Cell",
    "renderableClass" : "Note",
    "position" : {
      "x" : 779,
      "y" : 475
    },
    "minX" : 648,
    "maxX" : 910,
    "minY" : 450,
    "maxY" : 501,
    "prop" : {
      "x" : 648,
      "y" : 450,
      "width" : 262,
      "height" : 51
    },
    "textPosition" : {
      "x" : 741,
      "y" : 465
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    }
  }, {
    "id" : 82142,
    "displayName" : "Innocent bystander cell",
    "renderableClass" : "Note",
    "position" : {
      "x" : 2881,
      "y" : 377
    },
    "minX" : 2765,
    "maxX" : 2998,
    "minY" : 359,
    "maxY" : 396,
    "prop" : {
      "x" : 2765,
      "y" : 359,
      "width" : 233,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2804,
      "y" : 367
    }
  } ],
  "links" : [ {
    "id" : 82153,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 728,
      "y" : 1302
    },
    "minX" : 693,
    "maxX" : 1609,
    "minY" : 1158,
    "maxY" : 1308,
    "segments" : [ {
      "from" : {
        "x" : 1609,
        "y" : 1307
      },
      "to" : {
        "x" : 728,
        "y" : 1302
      }
    }, {
      "from" : {
        "x" : 728,
        "y" : 1302
      },
      "to" : {
        "x" : 693,
        "y" : 1158
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 722,
        "y" : 1296
      },
      "b" : {
        "x" : 734,
        "y" : 1308
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 728,
        "y" : 1302
      }
    },
    "inputs" : [ {
      "id" : 82003
    } ],
    "outputs" : [ {
      "id" : 82015
    } ]
  }, {
    "id" : 82155,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1405,
      "y" : 1075
    },
    "minX" : 738,
    "maxX" : 1935,
    "minY" : 1069,
    "maxY" : 1123,
    "segments" : [ {
      "from" : {
        "x" : 1935,
        "y" : 1119
      },
      "to" : {
        "x" : 1858,
        "y" : 1073
      }
    }, {
      "from" : {
        "x" : 1858,
        "y" : 1073
      },
      "to" : {
        "x" : 953,
        "y" : 1077
      }
    }, {
      "from" : {
        "x" : 953,
        "y" : 1077
      },
      "to" : {
        "x" : 738,
        "y" : 1123
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1399,
        "y" : 1069
      },
      "b" : {
        "x" : 1411,
        "y" : 1081
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1405,
        "y" : 1075
      }
    },
    "inputs" : [ {
      "id" : 82008
    } ],
    "outputs" : [ {
      "id" : 82015
    } ]
  }, {
    "id" : 82154,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1288,
      "y" : 1099
    },
    "minX" : 746,
    "maxX" : 1641,
    "minY" : 1093,
    "maxY" : 1132,
    "segments" : [ {
      "from" : {
        "x" : 1641,
        "y" : 1131
      },
      "to" : {
        "x" : 1619,
        "y" : 1099
      }
    }, {
      "from" : {
        "x" : 1619,
        "y" : 1099
      },
      "to" : {
        "x" : 957,
        "y" : 1099
      }
    }, {
      "from" : {
        "x" : 957,
        "y" : 1099
      },
      "to" : {
        "x" : 746,
        "y" : 1132
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1282,
        "y" : 1093
      },
      "b" : {
        "x" : 1294,
        "y" : 1105
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1288,
        "y" : 1099
      }
    },
    "inputs" : [ {
      "id" : 82006
    } ],
    "outputs" : [ {
      "id" : 82015
    } ]
  }, {
    "id" : 82157,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1403,
      "y" : 688
    },
    "minX" : 709,
    "maxX" : 2097,
    "minY" : 253,
    "maxY" : 1123,
    "segments" : [ {
      "from" : {
        "x" : 2097,
        "y" : 253
      },
      "to" : {
        "x" : 709,
        "y" : 1123
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1397,
        "y" : 682
      },
      "b" : {
        "x" : 1409,
        "y" : 694
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1403,
        "y" : 688
      }
    },
    "inputs" : [ {
      "id" : 82023
    } ],
    "outputs" : [ {
      "id" : 82015
    } ]
  }, {
    "id" : 82156,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1301,
      "y" : 687
    },
    "minX" : 706,
    "maxX" : 1896,
    "minY" : 251,
    "maxY" : 1123,
    "segments" : [ {
      "from" : {
        "x" : 1896,
        "y" : 251
      },
      "to" : {
        "x" : 706,
        "y" : 1123
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1295,
        "y" : 681
      },
      "b" : {
        "x" : 1307,
        "y" : 693
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1301,
        "y" : 687
      }
    },
    "inputs" : [ {
      "id" : 81993
    } ],
    "outputs" : [ {
      "id" : 82015
    } ]
  }, {
    "id" : 82159,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 3250,
      "y" : 111
    },
    "minX" : 2742,
    "maxX" : 3695,
    "minY" : 105,
    "maxY" : 246,
    "segments" : [ {
      "from" : {
        "x" : 2742,
        "y" : 246
      },
      "to" : {
        "x" : 2898,
        "y" : 112
      }
    }, {
      "from" : {
        "x" : 2898,
        "y" : 112
      },
      "to" : {
        "x" : 3602,
        "y" : 111
      }
    }, {
      "from" : {
        "x" : 3602,
        "y" : 111
      },
      "to" : {
        "x" : 3695,
        "y" : 246
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3244,
        "y" : 105
      },
      "b" : {
        "x" : 3256,
        "y" : 117
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3250,
        "y" : 111
      }
    },
    "inputs" : [ {
      "id" : 82039
    } ],
    "outputs" : [ {
      "id" : 82130
    } ]
  }, {
    "id" : 82163,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 234,
      "y" : 821
    },
    "minX" : 228,
    "maxX" : 240,
    "minY" : 768,
    "maxY" : 874,
    "segments" : [ {
      "from" : {
        "x" : 236,
        "y" : 874
      },
      "to" : {
        "x" : 232,
        "y" : 768
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 228,
        "y" : 815
      },
      "b" : {
        "x" : 240,
        "y" : 827
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 234,
        "y" : 821
      }
    },
    "inputs" : [ {
      "id" : 82079
    } ],
    "outputs" : [ {
      "id" : 82075
    } ]
  }, {
    "id" : 82165,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 354,
      "y" : 940
    },
    "minX" : 257,
    "maxX" : 360,
    "minY" : 899,
    "maxY" : 1025,
    "segments" : [ {
      "from" : {
        "x" : 257,
        "y" : 1025
      },
      "to" : {
        "x" : 355,
        "y" : 967
      }
    }, {
      "from" : {
        "x" : 355,
        "y" : 967
      },
      "to" : {
        "x" : 353,
        "y" : 913
      }
    }, {
      "from" : {
        "x" : 353,
        "y" : 913
      },
      "to" : {
        "x" : 286,
        "y" : 899
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 348,
        "y" : 934
      },
      "b" : {
        "x" : 360,
        "y" : 946
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 354,
        "y" : 940
      }
    },
    "inputs" : [ {
      "id" : 82084
    } ],
    "outputs" : [ {
      "id" : 82079
    } ]
  }, {
    "id" : 82166,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 371,
      "y" : 873
    },
    "minX" : 261,
    "maxX" : 377,
    "minY" : 757,
    "maxY" : 1025,
    "segments" : [ {
      "from" : {
        "x" : 261,
        "y" : 1025
      },
      "to" : {
        "x" : 373,
        "y" : 972
      }
    }, {
      "from" : {
        "x" : 373,
        "y" : 972
      },
      "to" : {
        "x" : 369,
        "y" : 775
      }
    }, {
      "from" : {
        "x" : 369,
        "y" : 775
      },
      "to" : {
        "x" : 281,
        "y" : 757
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 365,
        "y" : 867
      },
      "b" : {
        "x" : 377,
        "y" : 879
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 371,
        "y" : 873
      }
    },
    "inputs" : [ {
      "id" : 82084
    } ],
    "outputs" : [ {
      "id" : 82075
    } ]
  }, {
    "id" : 82169,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 2405,
      "y" : 503
    },
    "minX" : 2345,
    "maxX" : 2466,
    "minY" : 495,
    "maxY" : 512,
    "segments" : [ {
      "from" : {
        "x" : 2345,
        "y" : 512
      },
      "to" : {
        "x" : 2466,
        "y" : 495
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2399,
        "y" : 497
      },
      "b" : {
        "x" : 2411,
        "y" : 509
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2405,
        "y" : 503
      }
    },
    "inputs" : [ {
      "id" : 82127
    } ],
    "outputs" : [ {
      "id" : 82106
    } ]
  }, {
    "id" : 82170,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 2587,
      "y" : 383
    },
    "minX" : 2539,
    "maxX" : 2593,
    "minY" : 293,
    "maxY" : 477,
    "segments" : [ {
      "from" : {
        "x" : 2539,
        "y" : 293
      },
      "to" : {
        "x" : 2586,
        "y" : 293
      }
    }, {
      "from" : {
        "x" : 2586,
        "y" : 293
      },
      "to" : {
        "x" : 2588,
        "y" : 474
      }
    }, {
      "from" : {
        "x" : 2588,
        "y" : 474
      },
      "to" : {
        "x" : 2578,
        "y" : 477
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2581,
        "y" : 377
      },
      "b" : {
        "x" : 2593,
        "y" : 389
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2587,
        "y" : 383
      }
    },
    "inputs" : [ {
      "id" : 82030
    } ],
    "outputs" : [ {
      "id" : 82106
    } ]
  }, {
    "id" : 82173,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 348,
      "y" : 1261
    },
    "minX" : 316,
    "maxX" : 380,
    "minY" : 1218,
    "maxY" : 1304,
    "segments" : [ {
      "from" : {
        "x" : 316,
        "y" : 1304
      },
      "to" : {
        "x" : 380,
        "y" : 1218
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 342,
        "y" : 1255
      },
      "b" : {
        "x" : 354,
        "y" : 1267
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 348,
        "y" : 1261
      }
    },
    "inputs" : [ {
      "id" : 82111
    } ],
    "outputs" : [ {
      "id" : 82102
    } ]
  }, {
    "id" : 82174,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 428,
      "y" : 1258
    },
    "minX" : 397,
    "maxX" : 460,
    "minY" : 1218,
    "maxY" : 1298,
    "segments" : [ {
      "from" : {
        "x" : 460,
        "y" : 1298
      },
      "to" : {
        "x" : 397,
        "y" : 1218
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 422,
        "y" : 1252
      },
      "b" : {
        "x" : 434,
        "y" : 1264
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 428,
        "y" : 1258
      }
    },
    "inputs" : [ {
      "id" : 82112
    } ],
    "outputs" : [ {
      "id" : 82102
    } ]
  } ],
  "shadows" : [ {
    "id" : 82177,
    "reactomeId" : 10729236,
    "displayName" : "Terminal pathway of complement",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 2470,
      "y" : 359
    },
    "minX" : 2304,
    "maxX" : 2637,
    "minY" : 68,
    "maxY" : 650,
    "prop" : {
      "x" : 2304,
      "y" : 68,
      "width" : 333,
      "height" : 73
    },
    "points" : [ {
      "x" : 2304,
      "y" : 68
    }, {
      "x" : 2637,
      "y" : 68
    }, {
      "x" : 2637,
      "y" : 650
    }, {
      "x" : 2304,
      "y" : 650
    } ],
    "colour" : "#008000"
  }, {
    "id" : 82176,
    "reactomeId" : 10729118,
    "displayName" : "Activation of C3 and C5",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1292,
      "y" : 770
    },
    "minX" : 414,
    "maxX" : 2170,
    "minY" : 25,
    "maxY" : 1515,
    "prop" : {
      "x" : 414,
      "y" : 1409,
      "width" : 1756,
      "height" : 106
    },
    "points" : [ {
      "x" : 414,
      "y" : 25
    }, {
      "x" : 2170,
      "y" : 25
    }, {
      "x" : 2170,
      "y" : 1515
    }, {
      "x" : 414,
      "y" : 1515
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 82178,
    "reactomeId" : 10730026,
    "displayName" : "Regulation of Complement cascade",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 2508,
      "y" : 763
    },
    "minX" : 267,
    "maxX" : 4750,
    "minY" : 141,
    "maxY" : 1386,
    "prop" : {
      "x" : 2226,
      "y" : 650,
      "width" : 2524,
      "height" : 736
    },
    "points" : [ {
      "x" : 267,
      "y" : 141
    }, {
      "x" : 4750,
      "y" : 141
    }, {
      "x" : 4750,
      "y" : 1386
    }, {
      "x" : 267,
      "y" : 1386
    } ],
    "colour" : "#666666"
  }, {
    "id" : 82175,
    "reactomeId" : 10729114,
    "displayName" : "Initial triggering of complement",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1108,
      "y" : 702
    },
    "minX" : -10,
    "maxX" : 2226,
    "minY" : -4,
    "maxY" : 1409,
    "prop" : {
      "x" : -10,
      "y" : 141,
      "width" : 277,
      "height" : 1245
    },
    "points" : [ {
      "x" : -10,
      "y" : -4
    }, {
      "x" : 2226,
      "y" : -4
    }, {
      "x" : 2226,
      "y" : 1409
    }, {
      "x" : -10,
      "y" : 1409
    } ],
    "colour" : "#4684ee"
  } ],
  "minX" : 0,
  "maxX" : 4746,
  "minY" : 0,
  "maxY" : 1505,
  "disease" : false
}