{ "dbId" : 10224659, "stableId" : "R-RNO-9937848", "displayName" : "CHD chromatin remodelers", "nodes" : [ { "id" : 92929, "reactomeId" : 10221171, "displayName" : "CHD1,CHD2:H3K4me3 chromatin", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 549, "y" : 1248 }, "minX" : 497, "maxX" : 607, "minY" : 1213, "maxY" : 1277, "prop" : { "x" : 497, "y" : 1219, "width" : 104, "height" : 58 }, "textPosition" : { "x" : 507, "y" : 1228 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 601, "y" : 1219 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 601, "y" : 1219 } } }, "connectors" : [ { "edgeId" : 92926, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92928, "reactomeId" : 10221167, "displayName" : "CHD1,CHD2", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 355, "y" : 1223 }, "minX" : 315, "maxX" : 408, "minY" : 1212, "maxY" : 1255, "prop" : { "x" : 315, "y" : 1212, "width" : 81, "height" : 23 }, "textPosition" : { "x" : 315, "y" : 1213 }, "connectors" : [ { "edgeId" : 92926, "type" : "INPUT", "segments" : [ { "from" : { "x" : 374, "y" : 1241 }, "to" : { "x" : 408, "y" : 1255 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92931, "reactomeId" : 10221175, "displayName" : "CHD1:H3K4me3 chromatin", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 548, "y" : 1322 }, "minX" : 493, "maxX" : 621, "minY" : 1298, "maxY" : 1381, "prop" : { "x" : 493, "y" : 1304, "width" : 110, "height" : 37 }, "textPosition" : { "x" : 493, "y" : 1306 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 603, "y" : 1304 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 603, "y" : 1304 } } }, "connectors" : [ { "edgeId" : 92930, "type" : "INPUT", "segments" : [ { "from" : { "x" : 570, "y" : 1344 }, "to" : { "x" : 621, "y" : 1381 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92933, "reactomeId" : 10112613, "displayName" : "PAF1C", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 514, "y" : 1386 }, "minX" : 491, "maxX" : 621, "minY" : 1369, "maxY" : 1398, "prop" : { "x" : 491, "y" : 1375, "width" : 46, "height" : 23 }, "textPosition" : { "x" : 494, "y" : 1363 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 537, "y" : 1375 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 537, "y" : 1375 } } }, "connectors" : [ { "edgeId" : 92930, "type" : "INPUT", "segments" : [ { "from" : { "x" : 540, "y" : 1384 }, "to" : { "x" : 621, "y" : 1381 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92932, "reactomeId" : 10112521, "displayName" : "FACT complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 523, "y" : 1432 }, "minX" : 477, "maxX" : 621, "minY" : 1381, "maxY" : 1444, "prop" : { "x" : 477, "y" : 1421, "width" : 92, "height" : 23 }, "textPosition" : { "x" : 493, "y" : 1409 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 569, "y" : 1421 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 569, "y" : 1421 } } }, "connectors" : [ { "edgeId" : 92930, "type" : "INPUT", "segments" : [ { "from" : { "x" : 545, "y" : 1418 }, "to" : { "x" : 621, "y" : 1381 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92935, "reactomeId" : 10221177, "displayName" : "CHD1:H3K4 nucleosome:FACT complex:U2 snRNP complex:PAF1C complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 762, "y" : 1383 }, "minX" : 701, "maxX" : 830, "minY" : 1338, "maxY" : 1423, "prop" : { "x" : 701, "y" : 1344, "width" : 123, "height" : 79 }, "textPosition" : { "x" : 701, "y" : 1346 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 824, "y" : 1344 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 824, "y" : 1344 } } }, "connectors" : [ { "edgeId" : 92930, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92934, "reactomeId" : 10215770, "displayName" : "U2 snRNP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 607, "y" : 1475 }, "minX" : 574, "maxX" : 646, "minY" : 1381, "maxY" : 1487, "prop" : { "x" : 574, "y" : 1464, "width" : 66, "height" : 23 }, "textPosition" : { "x" : 583, "y" : 1452 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 640, "y" : 1464 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 640, "y" : 1464 } } }, "connectors" : [ { "edgeId" : 92930, "type" : "INPUT", "segments" : [ { "from" : { "x" : 608, "y" : 1461 }, "to" : { "x" : 621, "y" : 1381 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92937, "reactomeId" : 113518, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1202, "y" : 923 }, "minX" : 1181, "maxX" : 1286, "minY" : 907, "maxY" : 1016, "prop" : { "x" : 1181, "y" : 908, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 1185, "y" : 913 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1219, "y" : 913 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1219, "y" : 913 } } }, "connectors" : [ { "edgeId" : 92936, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1216, "y" : 942 }, "to" : { "x" : 1286, "y" : 1016 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 92939, "reactomeId" : 10221198, "displayName" : "chromatin", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1164, "y" : 1047 }, "minX" : 1131, "maxX" : 1370, "minY" : 1016, "maxY" : 1064, "prop" : { "x" : 1131, "y" : 1036, "width" : 66, "height" : 23 }, "textPosition" : { "x" : 1132, "y" : 1024 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1197, "y" : 1036 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1197, "y" : 1036 } } }, "connectors" : [ { "edgeId" : 92936, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1200, "y" : 1038 }, "to" : { "x" : 1286, "y" : 1016 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92936, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1200, "y" : 1052 }, "to" : { "x" : 1267, "y" : 1064 } }, { "from" : { "x" : 1267, "y" : 1064 }, "to" : { "x" : 1352, "y" : 1062 } }, { "from" : { "x" : 1352, "y" : 1062 }, "to" : { "x" : 1370, "y" : 1016 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1208, "y" : 1049 }, "b" : { "x" : 1200, "y" : 1052 }, "c" : { "x" : 1206, "y" : 1057 }, "type" : "ARROW", "centre" : { "x" : 1206, "y" : 1057 } } } ] }, { "id" : 92938, "reactomeId" : 29358, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1193, "y" : 999 }, "minX" : 1173, "maxX" : 1286, "minY" : 983, "maxY" : 1016, "prop" : { "x" : 1173, "y" : 984, "width" : 40, "height" : 31 }, "textPosition" : { "x" : 1177, "y" : 989 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1208, "y" : 989 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1208, "y" : 989 } } }, "connectors" : [ { "edgeId" : 92936, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1216, "y" : 1002 }, "to" : { "x" : 1286, "y" : 1016 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92941, "reactomeId" : 9668967, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1461, "y" : 999 }, "minX" : 1370, "maxX" : 1480, "minY" : 983, "maxY" : 1016, "prop" : { "x" : 1443, "y" : 984, "width" : 36, "height" : 31 }, "textPosition" : { "x" : 1447, "y" : 989 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1474, "y" : 989 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1474, "y" : 989 } } }, "connectors" : [ { "edgeId" : 92936, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1440, "y" : 1002 }, "to" : { "x" : 1370, "y" : 1016 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1434, "y" : 1007 }, "b" : { "x" : 1440, "y" : 1002 }, "c" : { "x" : 1432, "y" : 999 }, "type" : "ARROW", "centre" : { "x" : 1432, "y" : 999 } } } ], "trivial" : true }, { "id" : 92940, "reactomeId" : 113582, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1445, "y" : 950 }, "minX" : 1370, "maxX" : 1467, "minY" : 934, "maxY" : 1016, "prop" : { "x" : 1425, "y" : 935, "width" : 41, "height" : 31 }, "textPosition" : { "x" : 1429, "y" : 940 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1461, "y" : 940 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1461, "y" : 940 } } }, "connectors" : [ { "edgeId" : 92936, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1427, "y" : 969 }, "to" : { "x" : 1370, "y" : 1016 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1424, "y" : 976 }, "b" : { "x" : 1427, "y" : 969 }, "c" : { "x" : 1419, "y" : 970 }, "type" : "ARROW", "centre" : { "x" : 1419, "y" : 970 } } } ] }, { "id" : 92943, "reactomeId" : 10221208, "displayName" : "CHD6,CHD7,CHD8,(CHD9)", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1309, "y" : 927 }, "minX" : 1248, "maxX" : 1371, "minY" : 909, "maxY" : 1007, "prop" : { "x" : 1248, "y" : 909, "width" : 123, "height" : 37 }, "textPosition" : { "x" : 1248, "y" : 910 }, "connectors" : [ { "edgeId" : 92936, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1310, "y" : 952 }, "to" : { "x" : 1314, "y" : 999 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1315, "y" : 1003 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1315, "y" : 1003 } } } ] }, { "id" : 92942, "reactomeId" : 113550, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1436, "y" : 1041 }, "minX" : 1370, "maxX" : 1451, "minY" : 1016, "maxY" : 1057, "prop" : { "x" : 1423, "y" : 1026, "width" : 27, "height" : 31 }, "textPosition" : { "x" : 1427, "y" : 1031 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1445, "y" : 1031 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1445, "y" : 1031 } } }, "connectors" : [ { "edgeId" : 92936, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1420, "y" : 1035 }, "to" : { "x" : 1370, "y" : 1016 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1412, "y" : 1036 }, "b" : { "x" : 1420, "y" : 1035 }, "c" : { "x" : 1415, "y" : 1029 }, "type" : "ARROW", "centre" : { "x" : 1415, "y" : 1029 } } } ] }, { "id" : 92945, "reactomeId" : 10221213, "displayName" : "CHD8,(CHD7)", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 1432, "y" : 1256 }, "minX" : 1388, "maxX" : 1525, "minY" : 1245, "maxY" : 1268, "prop" : { "x" : 1388, "y" : 1245, "width" : 89, "height" : 23 }, "textPosition" : { "x" : 1406, "y" : 1239 }, "connectors" : [ { "edgeId" : 92944, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1483, "y" : 1256 }, "to" : { "x" : 1525, "y" : 1256 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92947, "reactomeId" : 10221219, "displayName" : "CTCF:CHD8,(CHD7)", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1659, "y" : 1252 }, "minX" : 1612, "maxX" : 1713, "minY" : 1224, "maxY" : 1274, "prop" : { "x" : 1612, "y" : 1230, "width" : 95, "height" : 44 }, "textPosition" : { "x" : 1619, "y" : 1239 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1707, "y" : 1230 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1707, "y" : 1230 } } }, "connectors" : [ { "edgeId" : 92944, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92946, "reactomeId" : 10221217, "displayName" : "Ctcf", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1495, "y" : 1195 }, "minX" : 1476, "maxX" : 1525, "minY" : 1178, "maxY" : 1256, "prop" : { "x" : 1476, "y" : 1184, "width" : 39, "height" : 23 }, "textPosition" : { "x" : 1479, "y" : 1185 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1515, "y" : 1184 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1515, "y" : 1184 } } }, "connectors" : [ { "edgeId" : 92944, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1500, "y" : 1210 }, "to" : { "x" : 1525, "y" : 1256 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92949, "reactomeId" : 10221226, "displayName" : "Fam124b", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1434, "y" : 1442 }, "minX" : 1402, "maxX" : 1517, "minY" : 1425, "maxY" : 1454, "prop" : { "x" : 1402, "y" : 1431, "width" : 64, "height" : 23 }, "textPosition" : { "x" : 1405, "y" : 1425 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1466, "y" : 1431 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1466, "y" : 1431 } } }, "connectors" : [ { "edgeId" : 92948, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1469, "y" : 1444 }, "to" : { "x" : 1517, "y" : 1449 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92951, "reactomeId" : 10221206, "displayName" : "Chd7", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1438, "y" : 1403 }, "minX" : 1417, "maxX" : 1517, "minY" : 1386, "maxY" : 1449, "prop" : { "x" : 1417, "y" : 1392, "width" : 43, "height" : 23 }, "textPosition" : { "x" : 1418, "y" : 1393 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1460, "y" : 1392 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1460, "y" : 1392 } } }, "connectors" : [ { "edgeId" : 92948, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1457, "y" : 1418 }, "to" : { "x" : 1517, "y" : 1449 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92950, "reactomeId" : 10176968, "displayName" : "CHD8", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1447, "y" : 1496 }, "minX" : 1426, "maxX" : 1517, "minY" : 1449, "maxY" : 1564, "prop" : { "x" : 1426, "y" : 1485, "width" : 43, "height" : 23 }, "textPosition" : { "x" : 1426, "y" : 1486 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1469, "y" : 1485 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1469, "y" : 1485 } } }, "connectors" : [ { "edgeId" : 92948, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1464, "y" : 1482 }, "to" : { "x" : 1517, "y" : 1449 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92953, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1472, "y" : 1500 }, "to" : { "x" : 1512, "y" : 1509 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92956, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1457, "y" : 1511 }, "to" : { "x" : 1511, "y" : 1564 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92952, "reactomeId" : 10221228, "displayName" : "CHD7:CHD8:FAM124B", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1646, "y" : 1451 }, "minX" : 1604, "maxX" : 1695, "minY" : 1427, "maxY" : 1470, "prop" : { "x" : 1604, "y" : 1433, "width" : 85, "height" : 37 }, "textPosition" : { "x" : 1604, "y" : 1435 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1689, "y" : 1433 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1689, "y" : 1433 } } }, "connectors" : [ { "edgeId" : 92948, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92955, "reactomeId" : 10221232, "displayName" : "CHD8:WDR5", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1654, "y" : 1512 }, "minX" : 1611, "maxX" : 1703, "minY" : 1491, "maxY" : 1527, "prop" : { "x" : 1611, "y" : 1497, "width" : 86, "height" : 30 }, "textPosition" : { "x" : 1613, "y" : 1506 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1697, "y" : 1497 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1697, "y" : 1497 } } }, "connectors" : [ { "edgeId" : 92953, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92954, "reactomeId" : 10170539, "displayName" : "Wdr5", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1449, "y" : 1549 }, "minX" : 1427, "maxX" : 1512, "minY" : 1509, "maxY" : 1561, "prop" : { "x" : 1427, "y" : 1538, "width" : 44, "height" : 23 }, "textPosition" : { "x" : 1429, "y" : 1539 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1471, "y" : 1538 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1471, "y" : 1538 } } }, "connectors" : [ { "edgeId" : 92953, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1467, "y" : 1535 }, "to" : { "x" : 1512, "y" : 1509 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92957, "reactomeId" : 10125091, "displayName" : "Ctnnb1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1440, "y" : 1602 }, "minX" : 1411, "maxX" : 1511, "minY" : 1564, "maxY" : 1614, "prop" : { "x" : 1411, "y" : 1591, "width" : 58, "height" : 23 }, "textPosition" : { "x" : 1413, "y" : 1592 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1469, "y" : 1591 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1469, "y" : 1591 } } }, "connectors" : [ { "edgeId" : 92956, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1461, "y" : 1588 }, "to" : { "x" : 1511, "y" : 1564 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92958, "reactomeId" : 10176970, "displayName" : "CTNNB1:CHD8", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1651, "y" : 1572 }, "minX" : 1602, "maxX" : 1706, "minY" : 1553, "maxY" : 1585, "prop" : { "x" : 1602, "y" : 1559, "width" : 98, "height" : 26 }, "textPosition" : { "x" : 1603, "y" : 1564 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1700, "y" : 1559 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1700, "y" : 1559 } } }, "connectors" : [ { "edgeId" : 92956, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92961, "reactomeId" : 10221238, "displayName" : "FBP1 gene:H3K4me3 nucleosome", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 890, "y" : 532 }, "minX" : 838, "maxX" : 948, "minY" : 437, "maxY" : 557, "prop" : { "x" : 838, "y" : 507, "width" : 104, "height" : 50 }, "textPosition" : { "x" : 848, "y" : 508 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 942, "y" : 507 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 942, "y" : 507 } } }, "connectors" : [ { "edgeId" : 92959, "type" : "INPUT", "segments" : [ { "from" : { "x" : 898, "y" : 504 }, "to" : { "x" : 923, "y" : 437 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92960, "reactomeId" : 10221242, "displayName" : "Tcf19", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 981, "y" : 577 }, "minX" : 923, "maxX" : 1174, "minY" : 373, "maxY" : 589, "prop" : { "x" : 958, "y" : 566, "width" : 47, "height" : 23 }, "textPosition" : { "x" : 960, "y" : 567 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1005, "y" : 566 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1005, "y" : 566 } } }, "connectors" : [ { "edgeId" : 92963, "type" : "INPUT", "segments" : [ { "from" : { "x" : 981, "y" : 563 }, "to" : { "x" : 996, "y" : 373 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92966, "type" : "INPUT", "segments" : [ { "from" : { "x" : 995, "y" : 563 }, "to" : { "x" : 1174, "y" : 428 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92959, "type" : "INPUT", "segments" : [ { "from" : { "x" : 976, "y" : 563 }, "to" : { "x" : 923, "y" : 437 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92962, "reactomeId" : 10221244, "displayName" : "TCF19:NuRD:FBP1 gene:H3K4 nucleosome", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 858, "y" : 367 }, "minX" : 798, "maxX" : 924, "minY" : 336, "maxY" : 393, "prop" : { "x" : 798, "y" : 342, "width" : 120, "height" : 51 }, "textPosition" : { "x" : 797, "y" : 344 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 918, "y" : 342 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 918, "y" : 342 } } }, "connectors" : [ { "edgeId" : 92959, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92965, "reactomeId" : 10221252, "displayName" : "TCF19:NuRD:G6PC gene:H3K4 nucleosome", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 982, "y" : 301 }, "minX" : 920, "maxX" : 1050, "minY" : 270, "maxY" : 327, "prop" : { "x" : 920, "y" : 276, "width" : 124, "height" : 51 }, "textPosition" : { "x" : 920, "y" : 278 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1044, "y" : 276 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1044, "y" : 276 } } }, "connectors" : [ { "edgeId" : 92963, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92964, "reactomeId" : 10221250, "displayName" : "G6PC gene:H3K4me3 nucleosome", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1087, "y" : 426 }, "minX" : 996, "maxX" : 1142, "minY" : 373, "maxY" : 452, "prop" : { "x" : 1039, "y" : 401, "width" : 97, "height" : 51 }, "textPosition" : { "x" : 1045, "y" : 403 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1136, "y" : 401 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1136, "y" : 401 } } }, "connectors" : [ { "edgeId" : 92963, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1043, "y" : 398 }, "to" : { "x" : 996, "y" : 373 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92967, "reactomeId" : 10221258, "displayName" : "PCK1 gene:H3K4me3 nucleosome", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1200, "y" : 525 }, "minX" : 1159, "maxX" : 1247, "minY" : 428, "maxY" : 553, "prop" : { "x" : 1159, "y" : 498, "width" : 82, "height" : 55 }, "textPosition" : { "x" : 1160, "y" : 490 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1241, "y" : 498 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1241, "y" : 498 } } }, "connectors" : [ { "edgeId" : 92966, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1192, "y" : 495 }, "to" : { "x" : 1174, "y" : 428 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92968, "reactomeId" : 10221260, "displayName" : "TCF19:NuRD:PCK1 gene:H3K4 nucleosome", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1178, "y" : 258 }, "minX" : 1117, "maxX" : 1246, "minY" : 227, "maxY" : 284, "prop" : { "x" : 1117, "y" : 233, "width" : 123, "height" : 51 }, "textPosition" : { "x" : 1117, "y" : 235 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1240, "y" : 233 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1240, "y" : 233 } } }, "connectors" : [ { "edgeId" : 92966, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92971, "reactomeId" : 10221278, "displayName" : "IKZF1,IKZF2,IKZF3:NuRD", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1696, "y" : 478 }, "minX" : 1638, "maxX" : 1761, "minY" : 454, "maxY" : 497, "prop" : { "x" : 1638, "y" : 460, "width" : 117, "height" : 37 }, "textPosition" : { "x" : 1654, "y" : 462 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1755, "y" : 460 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1755, "y" : 460 } } }, "connectors" : [ { "edgeId" : 92969, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92970, "reactomeId" : 10221276, "displayName" : "IKZF1,IKZF2,IKZF3", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1467, "y" : 486 }, "minX" : 1429, "maxX" : 1550, "minY" : 463, "maxY" : 516, "prop" : { "x" : 1429, "y" : 463, "width" : 76, "height" : 47 }, "textPosition" : { "x" : 1444, "y" : 462 }, "connectors" : [ { "edgeId" : 92969, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1511, "y" : 499 }, "to" : { "x" : 1550, "y" : 516 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92875, "reactomeId" : 10107607, "displayName" : "MTA1, MTA2, MTA3", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 353, "y" : 562 }, "minX" : 288, "maxX" : 419, "minY" : 544, "maxY" : 623, "prop" : { "x" : 288, "y" : 544, "width" : 131, "height" : 37 }, "textPosition" : { "x" : 292, "y" : 552 }, "connectors" : [ { "edgeId" : 92873, "type" : "INPUT", "segments" : [ { "from" : { "x" : 367, "y" : 587 }, "to" : { "x" : 400, "y" : 623 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 377, "y" : 599 }, "b" : { "x" : 389, "y" : 611 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 383, "y" : 605 } } } } ] }, { "id" : 92874, "reactomeId" : 10128435, "displayName" : "RBBP4,7", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 306, "y" : 628 }, "minX" : 262, "maxX" : 400, "minY" : 610, "maxY" : 647, "prop" : { "x" : 262, "y" : 610, "width" : 89, "height" : 37 }, "textPosition" : { "x" : 276, "y" : 618 }, "connectors" : [ { "edgeId" : 92873, "type" : "INPUT", "segments" : [ { "from" : { "x" : 357, "y" : 625 }, "to" : { "x" : 400, "y" : 623 } } ], "stoichiometry" : { "value" : 4, "shape" : { "a" : { "x" : 372, "y" : 618 }, "b" : { "x" : 384, "y" : 630 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 378, "y" : 624 } } } } ] }, { "id" : 92877, "reactomeId" : 10220831, "displayName" : "HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 546, "y" : 623 }, "minX" : 481, "maxX" : 678, "minY" : 531, "maxY" : 649, "prop" : { "x" : 481, "y" : 598, "width" : 131, "height" : 51 }, "textPosition" : { "x" : 483, "y" : 600 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 612, "y" : 598 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 612, "y" : 598 } } }, "connectors" : [ { "edgeId" : 92873, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92878, "type" : "INPUT", "segments" : [ { "from" : { "x" : 565, "y" : 595 }, "to" : { "x" : 616, "y" : 531 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92881, "type" : "INPUT", "segments" : [ { "from" : { "x" : 615, "y" : 622 }, "to" : { "x" : 678, "y" : 621 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92876, "reactomeId" : 10220829, "displayName" : "HDAC1,HDAC2", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 325, "y" : 698 }, "minX" : 273, "maxX" : 400, "minY" : 623, "maxY" : 717, "prop" : { "x" : 273, "y" : 680, "width" : 105, "height" : 37 }, "textPosition" : { "x" : 277, "y" : 688 }, "connectors" : [ { "edgeId" : 92873, "type" : "INPUT", "segments" : [ { "from" : { "x" : 343, "y" : 674 }, "to" : { "x" : 400, "y" : 623 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 365, "y" : 642 }, "b" : { "x" : 377, "y" : 654 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 371, "y" : 648 } } } } ] }, { "id" : 92879, "reactomeId" : 10220837, "displayName" : "Pwwp2a", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 527, "y" : 514 }, "minX" : 467, "maxX" : 616, "minY" : 490, "maxY" : 533, "prop" : { "x" : 467, "y" : 496, "width" : 120, "height" : 37 }, "textPosition" : { "x" : 498, "y" : 504 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 587, "y" : 496 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 587, "y" : 496 } } }, "connectors" : [ { "edgeId" : 92878, "type" : "INPUT", "segments" : [ { "from" : { "x" : 593, "y" : 525 }, "to" : { "x" : 616, "y" : 531 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92880, "reactomeId" : 10220839, "displayName" : "HDAC1, HDAC2:MTA1,MTA2,MTA3:RBBP4,RBBP7:PWWP2A,PWWP2B", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 737, "y" : 532 }, "minX" : 676, "maxX" : 805, "minY" : 487, "maxY" : 572, "prop" : { "x" : 676, "y" : 493, "width" : 123, "height" : 79 }, "textPosition" : { "x" : 677, "y" : 509 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 799, "y" : 493 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 799, "y" : 493 } } }, "connectors" : [ { "edgeId" : 92878, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92883, "reactomeId" : 10220858, "displayName" : "MBD2,MBD3", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 689, "y" : 683 }, "minX" : 649, "maxX" : 730, "minY" : 621, "maxY" : 695, "prop" : { "x" : 649, "y" : 672, "width" : 81, "height" : 23 }, "textPosition" : { "x" : 666, "y" : 666 }, "connectors" : [ { "edgeId" : 92881, "type" : "INPUT", "segments" : [ { "from" : { "x" : 686, "y" : 666 }, "to" : { "x" : 678, "y" : 621 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92882, "reactomeId" : 10220864, "displayName" : "SUMO1-GATAD2A, SUMO1-GATAD2B", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 568, "y" : 687 }, "minX" : 507, "maxX" : 678, "minY" : 621, "maxY" : 706, "prop" : { "x" : 507, "y" : 669, "width" : 123, "height" : 37 }, "textPosition" : { "x" : 508, "y" : 670 }, "connectors" : [ { "edgeId" : 92881, "type" : "INPUT", "segments" : [ { "from" : { "x" : 598, "y" : 663 }, "to" : { "x" : 678, "y" : 621 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92884, "reactomeId" : 10220866, "displayName" : "HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 863, "y" : 625 }, "minX" : 788, "maxX" : 984, "minY" : 584, "maxY" : 661, "prop" : { "x" : 788, "y" : 590, "width" : 151, "height" : 71 }, "textPosition" : { "x" : 791, "y" : 598 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 939, "y" : 590 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 939, "y" : 590 } } }, "connectors" : [ { "edgeId" : 92881, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92885, "type" : "INPUT", "segments" : [ { "from" : { "x" : 942, "y" : 626 }, "to" : { "x" : 984, "y" : 628 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92887, "reactomeId" : 10220884, "displayName" : "CHD3, CHD4, CHD5", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1032, "y" : 698 }, "minX" : 978, "maxX" : 1086, "minY" : 628, "maxY" : 720, "prop" : { "x" : 978, "y" : 677, "width" : 108, "height" : 43 }, "textPosition" : { "x" : 986, "y" : 681 }, "connectors" : [ { "edgeId" : 92885, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1017, "y" : 671 }, "to" : { "x" : 984, "y" : 628 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92886, "reactomeId" : 10220878, "displayName" : "CDK2AP1,CDK2AP2", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 913, "y" : 704 }, "minX" : 870, "maxX" : 984, "minY" : 628, "maxY" : 724, "prop" : { "x" : 870, "y" : 684, "width" : 86, "height" : 40 }, "textPosition" : { "x" : 879, "y" : 686 }, "connectors" : [ { "edgeId" : 92885, "type" : "INPUT", "segments" : [ { "from" : { "x" : 931, "y" : 678 }, "to" : { "x" : 984, "y" : 628 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92888, "reactomeId" : 10220886, "displayName" : "NuRD", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1095, "y" : 628 }, "minX" : 923, "maxX" : 1561, "minY" : 341, "maxY" : 644, "prop" : { "x" : 1064, "y" : 613, "width" : 63, "height" : 31 }, "textPosition" : { "x" : 1074, "y" : 623 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1127, "y" : 613 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1127, "y" : 613 } } }, "connectors" : [ { "edgeId" : 92963, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1088, "y" : 610 }, "to" : { "x" : 996, "y" : 373 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92966, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1101, "y" : 610 }, "to" : { "x" : 1174, "y" : 428 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92969, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1130, "y" : 620 }, "to" : { "x" : 1550, "y" : 516 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92914, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1130, "y" : 613 }, "to" : { "x" : 1350, "y" : 509 } }, { "from" : { "x" : 1350, "y" : 509 }, "to" : { "x" : 1561, "y" : 341 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92885, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92923, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1130, "y" : 622 }, "to" : { "x" : 1501, "y" : 557 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92959, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1081, "y" : 610 }, "to" : { "x" : 923, "y" : 437 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92891, "reactomeId" : 10107611, "displayName" : "Gatad2a", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 449, "y" : 889 }, "minX" : 416, "maxX" : 498, "minY" : 853, "maxY" : 901, "prop" : { "x" : 416, "y" : 878, "width" : 67, "height" : 23 }, "textPosition" : { "x" : 418, "y" : 879 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 483, "y" : 878 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 483, "y" : 878 } } }, "connectors" : [ { "edgeId" : 92889, "type" : "INPUT", "segments" : [ { "from" : { "x" : 464, "y" : 875 }, "to" : { "x" : 498, "y" : 853 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92890, "reactomeId" : 10168575, "displayName" : "SUMO1:C93-UBE2I", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 556, "y" : 904 }, "minX" : 498, "maxX" : 616, "minY" : 833, "maxY" : 924, "prop" : { "x" : 517, "y" : 884, "width" : 78, "height" : 40 }, "textPosition" : { "x" : 520, "y" : 889 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 595, "y" : 884 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 595, "y" : 884 } } }, "connectors" : [ { "edgeId" : 92889, "type" : "INPUT", "segments" : [ { "from" : { "x" : 533, "y" : 881 }, "to" : { "x" : 498, "y" : 853 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 509, "y" : 861 }, "b" : { "x" : 521, "y" : 873 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 515, "y" : 867 } } } }, { "edgeId" : 92889, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 540, "y" : 881 }, "to" : { "x" : 507, "y" : 840 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 505, "y" : 837 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 505, "y" : 837 } } }, { "edgeId" : 92894, "type" : "INPUT", "segments" : [ { "from" : { "x" : 579, "y" : 881 }, "to" : { "x" : 616, "y" : 853 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92894, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 570, "y" : 881 }, "to" : { "x" : 602, "y" : 841 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 605, "y" : 837 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 605, "y" : 837 } } } ] }, { "id" : 92893, "reactomeId" : 10168567, "displayName" : "Ube2i", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 557, "y" : 787 }, "minX" : 498, "maxX" : 610, "minY" : 770, "maxY" : 812, "prop" : { "x" : 536, "y" : 776, "width" : 42, "height" : 23 }, "textPosition" : { "x" : 536, "y" : 770 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 578, "y" : 776 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 578, "y" : 776 } } }, "connectors" : [ { "edgeId" : 92889, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 533, "y" : 792 }, "to" : { "x" : 498, "y" : 803 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 509, "y" : 791 }, "b" : { "x" : 521, "y" : 803 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 515, "y" : 797 } } }, "endShape" : { "a" : { "x" : 528, "y" : 798 }, "b" : { "x" : 533, "y" : 792 }, "c" : { "x" : 525, "y" : 790 }, "type" : "ARROW", "centre" : { "x" : 525, "y" : 790 } } }, { "edgeId" : 92894, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 581, "y" : 796 }, "to" : { "x" : 610, "y" : 812 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 589, "y" : 796 }, "b" : { "x" : 581, "y" : 796 }, "c" : { "x" : 585, "y" : 803 }, "type" : "ARROW", "centre" : { "x" : 585, "y" : 803 } } } ] }, { "id" : 92892, "reactomeId" : 10220862, "displayName" : "Gatad2a", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 493, "y" : 742 }, "minX" : 437, "maxX" : 556, "minY" : 718, "maxY" : 803, "prop" : { "x" : 437, "y" : 724, "width" : 113, "height" : 37 }, "textPosition" : { "x" : 462, "y" : 732 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 550, "y" : 724 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 550, "y" : 724 } } }, "connectors" : [ { "edgeId" : 92889, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 494, "y" : 764 }, "to" : { "x" : 498, "y" : 803 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 499, "y" : 770 }, "b" : { "x" : 494, "y" : 764 }, "c" : { "x" : 491, "y" : 771 }, "type" : "ARROW", "centre" : { "x" : 491, "y" : 771 } } } ] }, { "id" : 92895, "reactomeId" : 10107615, "displayName" : "Gatad2b", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 665, "y" : 895 }, "minX" : 616, "maxX" : 704, "minY" : 853, "maxY" : 907, "prop" : { "x" : 632, "y" : 884, "width" : 66, "height" : 23 }, "textPosition" : { "x" : 634, "y" : 885 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 698, "y" : 884 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 698, "y" : 884 } } }, "connectors" : [ { "edgeId" : 92894, "type" : "INPUT", "segments" : [ { "from" : { "x" : 651, "y" : 881 }, "to" : { "x" : 616, "y" : 853 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92896, "reactomeId" : 10220854, "displayName" : "Gatad2b", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 625, "y" : 746 }, "minX" : 567, "maxX" : 690, "minY" : 722, "maxY" : 812, "prop" : { "x" : 567, "y" : 728, "width" : 117, "height" : 37 }, "textPosition" : { "x" : 594, "y" : 736 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 684, "y" : 728 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 684, "y" : 728 } } }, "connectors" : [ { "edgeId" : 92894, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 620, "y" : 768 }, "to" : { "x" : 610, "y" : 812 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 622, "y" : 776 }, "b" : { "x" : 620, "y" : 768 }, "c" : { "x" : 615, "y" : 774 }, "type" : "ARROW", "centre" : { "x" : 615, "y" : 774 } } } ] }, { "id" : 92899, "reactomeId" : 10220913, "displayName" : "CBX1,CBX3", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 302, "y" : 920 }, "minX" : 265, "maxX" : 360, "minY" : 909, "maxY" : 981, "prop" : { "x" : 265, "y" : 909, "width" : 75, "height" : 23 }, "textPosition" : { "x" : 265, "y" : 910 }, "connectors" : [ { "edgeId" : 92897, "type" : "INPUT", "segments" : [ { "from" : { "x" : 312, "y" : 938 }, "to" : { "x" : 360, "y" : 981 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92898, "reactomeId" : 10107583, "displayName" : "Chd4", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 297, "y" : 1023 }, "minX" : 276, "maxX" : 360, "minY" : 981, "maxY" : 1035, "prop" : { "x" : 276, "y" : 1012, "width" : 43, "height" : 23 }, "textPosition" : { "x" : 277, "y" : 1013 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 319, "y" : 1012 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 319, "y" : 1012 } } }, "connectors" : [ { "edgeId" : 92897, "type" : "INPUT", "segments" : [ { "from" : { "x" : 314, "y" : 1009 }, "to" : { "x" : 360, "y" : 981 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92901, "reactomeId" : 10220915, "displayName" : "ChAHP complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 466, "y" : 981 }, "minX" : 416, "maxX" : 523, "minY" : 964, "maxY" : 993, "prop" : { "x" : 416, "y" : 970, "width" : 101, "height" : 23 }, "textPosition" : { "x" : 437, "y" : 958 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 517, "y" : 970 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 517, "y" : 970 } } }, "connectors" : [ { "edgeId" : 92897, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92900, "reactomeId" : 10220907, "displayName" : "Adnp", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 282, "y" : 981 }, "minX" : 261, "maxX" : 360, "minY" : 964, "maxY" : 993, "prop" : { "x" : 261, "y" : 970, "width" : 42, "height" : 23 }, "textPosition" : { "x" : 262, "y" : 971 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 303, "y" : 970 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 303, "y" : 970 } } }, "connectors" : [ { "edgeId" : 92897, "type" : "INPUT", "segments" : [ { "from" : { "x" : 306, "y" : 981 }, "to" : { "x" : 360, "y" : 981 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92903, "reactomeId" : 10220982, "displayName" : "GATAD2A NuRD", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1566, "y" : 230 }, "minX" : 1514, "maxX" : 1676, "minY" : 213, "maxY" : 242, "prop" : { "x" : 1514, "y" : 219, "width" : 104, "height" : 23 }, "textPosition" : { "x" : 1514, "y" : 221 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1618, "y" : 219 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1618, "y" : 219 } } }, "connectors" : [ { "edgeId" : 92902, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1621, "y" : 229 }, "to" : { "x" : 1676, "y" : 229 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92905, "reactomeId" : 10221002, "displayName" : "ZMYND8:ZNF532:ZNF592:ZNF687:GATAD2A NuRD", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1802, "y" : 230 }, "minX" : 1746, "maxX" : 1865, "minY" : 199, "maxY" : 256, "prop" : { "x" : 1746, "y" : 205, "width" : 113, "height" : 51 }, "textPosition" : { "x" : 1751, "y" : 179 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1859, "y" : 205 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1859, "y" : 205 } } }, "connectors" : [ { "edgeId" : 92902, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92904, "reactomeId" : 10221000, "displayName" : "ZMYND8:ZNF532:ZNF592:ZNF687", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1619, "y" : 278 }, "minX" : 1563, "maxX" : 1682, "minY" : 229, "maxY" : 297, "prop" : { "x" : 1563, "y" : 260, "width" : 113, "height" : 37 }, "textPosition" : { "x" : 1564, "y" : 248 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1676, "y" : 260 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1676, "y" : 260 } } }, "connectors" : [ { "edgeId" : 92902, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1640, "y" : 257 }, "to" : { "x" : 1676, "y" : 229 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92907, "reactomeId" : 10220896, "displayName" : "HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,BBP7:MBD3:GATAD2A,GATAD2B", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 788, "y" : 762 }, "minX" : 724, "maxX" : 897, "minY" : 724, "maxY" : 795, "prop" : { "x" : 724, "y" : 730, "width" : 128, "height" : 65 }, "textPosition" : { "x" : 724, "y" : 732 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 852, "y" : 730 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 852, "y" : 730 } } }, "connectors" : [ { "edgeId" : 92906, "type" : "INPUT", "segments" : [ { "from" : { "x" : 855, "y" : 772 }, "to" : { "x" : 897, "y" : 780 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92909, "reactomeId" : 10220898, "displayName" : "MBD3L2:HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,RBBP7:MBD3:GATAD2A,GATAD2B", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1071, "y" : 778 }, "minX" : 1006, "maxX" : 1143, "minY" : 733, "maxY" : 818, "prop" : { "x" : 1006, "y" : 739, "width" : 131, "height" : 79 }, "textPosition" : { "x" : 1007, "y" : 741 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1137, "y" : 739 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1137, "y" : 739 } } }, "connectors" : [ { "edgeId" : 92906, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92908, "reactomeId" : 10220894, "displayName" : "Mbd3l2", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 792, "y" : 837 }, "minX" : 764, "maxX" : 897, "minY" : 780, "maxY" : 849, "prop" : { "x" : 764, "y" : 826, "width" : 57, "height" : 23 }, "textPosition" : { "x" : 766, "y" : 827 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 821, "y" : 826 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 821, "y" : 826 } } }, "connectors" : [ { "edgeId" : 92906, "type" : "INPUT", "segments" : [ { "from" : { "x" : 813, "y" : 823 }, "to" : { "x" : 897, "y" : 780 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92911, "reactomeId" : 10221095, "displayName" : "HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,BBP7:MBD2:GATAD2A,GATAD2B", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 845, "y" : 946 }, "minX" : 781, "maxX" : 915, "minY" : 876, "maxY" : 979, "prop" : { "x" : 781, "y" : 914, "width" : 128, "height" : 65 }, "textPosition" : { "x" : 781, "y" : 916 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 909, "y" : 914 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 909, "y" : 914 } } }, "connectors" : [ { "edgeId" : 92910, "type" : "INPUT", "segments" : [ { "from" : { "x" : 875, "y" : 911 }, "to" : { "x" : 910, "y" : 876 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92913, "reactomeId" : 10221097, "displayName" : "MBD3L1:HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,RBBP7:MBD2:GATAD2A,GATAD2B", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1075, "y" : 877 }, "minX" : 1010, "maxX" : 1147, "minY" : 832, "maxY" : 917, "prop" : { "x" : 1010, "y" : 838, "width" : 131, "height" : 79 }, "textPosition" : { "x" : 1011, "y" : 840 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1141, "y" : 838 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1141, "y" : 838 } } }, "connectors" : [ { "edgeId" : 92910, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92912, "reactomeId" : 10221093, "displayName" : "Mbd3l1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 793, "y" : 873 }, "minX" : 765, "maxX" : 910, "minY" : 856, "maxY" : 885, "prop" : { "x" : 765, "y" : 862, "width" : 57, "height" : 23 }, "textPosition" : { "x" : 767, "y" : 863 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 822, "y" : 862 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 822, "y" : 862 } } }, "connectors" : [ { "edgeId" : 92910, "type" : "INPUT", "segments" : [ { "from" : { "x" : 825, "y" : 873 }, "to" : { "x" : 910, "y" : 876 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92915, "reactomeId" : 10221118, "displayName" : "NR2C2,NR2F2", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1430, "y" : 300 }, "minX" : 1384, "maxX" : 1561, "minY" : 289, "maxY" : 341, "prop" : { "x" : 1384, "y" : 289, "width" : 93, "height" : 23 }, "textPosition" : { "x" : 1384, "y" : 290 }, "connectors" : [ { "edgeId" : 92914, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1466, "y" : 318 }, "to" : { "x" : 1561, "y" : 341 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92917, "reactomeId" : 10221105, "displayName" : "Chromatin (H4K5ac, H4K8ac)", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1389, "y" : 387 }, "minX" : 1335, "maxX" : 1561, "minY" : 341, "maxY" : 411, "prop" : { "x" : 1335, "y" : 363, "width" : 108, "height" : 48 }, "textPosition" : { "x" : 1351, "y" : 362 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1443, "y" : 363 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1443, "y" : 363 } } }, "connectors" : [ { "edgeId" : 92914, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1446, "y" : 372 }, "to" : { "x" : 1561, "y" : 341 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92916, "reactomeId" : 10221109, "displayName" : "Zfp827", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1386, "y" : 338 }, "minX" : 1359, "maxX" : 1561, "minY" : 321, "maxY" : 350, "prop" : { "x" : 1359, "y" : 327, "width" : 55, "height" : 23 }, "textPosition" : { "x" : 1360, "y" : 328 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1414, "y" : 327 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1414, "y" : 327 } } }, "connectors" : [ { "edgeId" : 92914, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1417, "y" : 338 }, "to" : { "x" : 1561, "y" : 341 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92918, "reactomeId" : 10221120, "displayName" : "NR2C2,NR2F2:ZNF827:NuRD:H4K5,H4K8 Ac telomeric chromatin", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1726, "y" : 342 }, "minX" : 1665, "maxX" : 1842, "minY" : 290, "maxY" : 375, "prop" : { "x" : 1665, "y" : 310, "width" : 123, "height" : 65 }, "textPosition" : { "x" : 1677, "y" : 298 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1788, "y" : 310 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1788, "y" : 310 } } }, "connectors" : [ { "edgeId" : 92914, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92919, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1791, "y" : 339 }, "to" : { "x" : 1813, "y" : 338 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 92919, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1783, "y" : 307 }, "to" : { "x" : 1818, "y" : 290 } }, { "from" : { "x" : 1818, "y" : 290 }, "to" : { "x" : 1836, "y" : 323 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1838, "y" : 326 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1838, "y" : 326 } } } ] }, { "id" : 92921, "reactomeId" : 10221124, "displayName" : "NR2C2,NR2F2:ZNF827:NuRD:telomeric chromatin", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1977, "y" : 331 }, "minX" : 1867, "maxX" : 2045, "minY" : 300, "maxY" : 357, "prop" : { "x" : 1916, "y" : 306, "width" : 123, "height" : 51 }, "textPosition" : { "x" : 1928, "y" : 294 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2039, "y" : 306 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2039, "y" : 306 } } }, "connectors" : [ { "edgeId" : 92919, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1913, "y" : 334 }, "to" : { "x" : 1867, "y" : 337 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1906, "y" : 338 }, "b" : { "x" : 1913, "y" : 334 }, "c" : { "x" : 1906, "y" : 330 }, "type" : "ARROW", "centre" : { "x" : 1906, "y" : 330 } } } ] }, { "id" : 92920, "reactomeId" : 113518, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1792, "y" : 402 }, "minX" : 1771, "maxX" : 1815, "minY" : 338, "maxY" : 418, "prop" : { "x" : 1771, "y" : 387, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 1775, "y" : 392 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1809, "y" : 392 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1809, "y" : 392 } } }, "connectors" : [ { "edgeId" : 92919, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1797, "y" : 384 }, "to" : { "x" : 1813, "y" : 338 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 1799, "y" : 355 }, "b" : { "x" : 1811, "y" : 367 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1805, "y" : 361 } } } } ], "trivial" : true }, { "id" : 92922, "reactomeId" : 5566518, "displayName" : "acetate", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1913, "y" : 401 }, "minX" : 1867, "maxX" : 1944, "minY" : 337, "maxY" : 417, "prop" : { "x" : 1884, "y" : 386, "width" : 59, "height" : 31 }, "textPosition" : { "x" : 1885, "y" : 391 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1938, "y" : 391 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1938, "y" : 391 } } }, "connectors" : [ { "edgeId" : 92919, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1901, "y" : 383 }, "to" : { "x" : 1867, "y" : 337 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 1878, "y" : 354 }, "b" : { "x" : 1890, "y" : 366 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1884, "y" : 360 } } }, "endShape" : { "a" : { "x" : 1894, "y" : 380 }, "b" : { "x" : 1901, "y" : 383 }, "c" : { "x" : 1900, "y" : 375 }, "type" : "ARROW", "centre" : { "x" : 1900, "y" : 375 } } } ] }, { "id" : 92925, "reactomeId" : 10221134, "displayName" : "PHF6:NuRD", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1603, "y" : 561 }, "minX" : 1568, "maxX" : 1645, "minY" : 537, "maxY" : 580, "prop" : { "x" : 1568, "y" : 543, "width" : 71, "height" : 37 }, "textPosition" : { "x" : 1581, "y" : 545 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1639, "y" : 543 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1639, "y" : 543 } } }, "connectors" : [ { "edgeId" : 92923, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92924, "reactomeId" : 10221132, "displayName" : "Phf6", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1458, "y" : 595 }, "minX" : 1439, "maxX" : 1501, "minY" : 557, "maxY" : 607, "prop" : { "x" : 1439, "y" : 584, "width" : 39, "height" : 23 }, "textPosition" : { "x" : 1440, "y" : 585 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1478, "y" : 584 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1478, "y" : 584 } } }, "connectors" : [ { "edgeId" : 92923, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1471, "y" : 581 }, "to" : { "x" : 1501, "y" : 557 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 92927, "reactomeId" : 10221169, "displayName" : "chromatin with H3K4me3 nucleosomes", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 337, "y" : 1305 }, "minX" : 289, "maxX" : 408, "minY" : 1255, "maxY" : 1331, "prop" : { "x" : 289, "y" : 1280, "width" : 97, "height" : 51 }, "textPosition" : { "x" : 288, "y" : 1282 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 386, "y" : 1280 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 386, "y" : 1280 } } }, "connectors" : [ { "edgeId" : 92926, "type" : "INPUT", "segments" : [ { "from" : { "x" : 373, "y" : 1277 }, "to" : { "x" : 408, "y" : 1255 } } ], "stoichiometry" : { "value" : 1 } } ] } ], "edges" : [ { "id" : 92897, "reactomeId" : 10220917, "displayName" : "Formation of ChAHP complex", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 379, "y" : 980 }, "minX" : 360, "maxX" : 413, "minY" : 974, "maxY" : 986, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 360, "y" : 981 }, "to" : { "x" : 379, "y" : 980 } }, { "from" : { "x" : 379, "y" : 980 }, "to" : { "x" : 413, "y" : 980 } } ], "endShape" : { "a" : { "x" : 406, "y" : 984 }, "b" : { "x" : 413, "y" : 980 }, "c" : { "x" : 406, "y" : 976 }, "type" : "ARROW", "centre" : { "x" : 406, "y" : 976 } }, "reactionShape" : { "c" : { "x" : 379, "y" : 980 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 379, "y" : 980 } }, "inputs" : [ { "id" : 92898, "points" : [ { "x" : 314, "y" : 1009 } ] }, { "id" : 92899, "points" : [ { "x" : 312, "y" : 938 } ] }, { "id" : 92900, "points" : [ { "x" : 306, "y" : 981 } ] } ], "outputs" : [ { "id" : 92901 } ] }, { "id" : 92963, "reactomeId" : 10221254, "displayName" : "NuRD binds TCF19 at G6PC gene", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 992, "y" : 353 }, "minX" : 986, "maxX" : 998, "minY" : 330, "maxY" : 373, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 996, "y" : 373 }, "to" : { "x" : 992, "y" : 353 } }, { "from" : { "x" : 992, "y" : 353 }, "to" : { "x" : 986, "y" : 330 } } ], "endShape" : { "a" : { "x" : 992, "y" : 336 }, "b" : { "x" : 986, "y" : 330 }, "c" : { "x" : 984, "y" : 338 }, "type" : "ARROW", "centre" : { "x" : 984, "y" : 338 } }, "reactionShape" : { "c" : { "x" : 992, "y" : 353 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 992, "y" : 353 } }, "inputs" : [ { "id" : 92960, "points" : [ { "x" : 981, "y" : 563 } ] }, { "id" : 92888, "points" : [ { "x" : 1088, "y" : 610 } ] }, { "id" : 92964, "points" : [ { "x" : 1043, "y" : 398 } ] } ], "outputs" : [ { "id" : 92965 } ] }, { "id" : 92930, "reactomeId" : 10221179, "displayName" : "CHD1:H3K4me3 interacts with post-initiation transcription complexes", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 652, "y" : 1381 }, "minX" : 621, "maxX" : 698, "minY" : 1375, "maxY" : 1387, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 621, "y" : 1381 }, "to" : { "x" : 652, "y" : 1381 } }, { "from" : { "x" : 652, "y" : 1381 }, "to" : { "x" : 698, "y" : 1381 } } ], "endShape" : { "a" : { "x" : 691, "y" : 1385 }, "b" : { "x" : 698, "y" : 1381 }, "c" : { "x" : 691, "y" : 1377 }, "type" : "ARROW", "centre" : { "x" : 691, "y" : 1377 } }, "reactionShape" : { "c" : { "x" : 652, "y" : 1381 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 652, "y" : 1381 } }, "inputs" : [ { "id" : 92931, "points" : [ { "x" : 570, "y" : 1344 } ] }, { "id" : 92932, "points" : [ { "x" : 545, "y" : 1418 } ] }, { "id" : 92933, "points" : [ { "x" : 540, "y" : 1384 } ] }, { "id" : 92934, "points" : [ { "x" : 608, "y" : 1461 } ] } ], "outputs" : [ { "id" : 92935 } ] }, { "id" : 92966, "reactomeId" : 10221262, "displayName" : "NuRD binds TCF19 at PCK1 gene", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1180, "y" : 319 }, "minX" : 1174, "maxX" : 1186, "minY" : 287, "maxY" : 428, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1174, "y" : 428 }, "to" : { "x" : 1180, "y" : 319 } }, { "from" : { "x" : 1180, "y" : 319 }, "to" : { "x" : 1178, "y" : 287 } } ], "endShape" : { "a" : { "x" : 1182, "y" : 294 }, "b" : { "x" : 1178, "y" : 287 }, "c" : { "x" : 1174, "y" : 294 }, "type" : "ARROW", "centre" : { "x" : 1174, "y" : 294 } }, "reactionShape" : { "c" : { "x" : 1180, "y" : 319 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1180, "y" : 319 } }, "inputs" : [ { "id" : 92960, "points" : [ { "x" : 995, "y" : 563 } ] }, { "id" : 92888, "points" : [ { "x" : 1101, "y" : 610 } ] }, { "id" : 92967, "points" : [ { "x" : 1192, "y" : 495 } ] } ], "outputs" : [ { "id" : 92968 } ] }, { "id" : 92902, "reactomeId" : 10221004, "displayName" : "GATAD2A NuRD binds ZMYND8:ZNF532:ZNF592:ZNF687", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1701, "y" : 228 }, "minX" : 1676, "maxX" : 1743, "minY" : 222, "maxY" : 234, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1676, "y" : 229 }, "to" : { "x" : 1701, "y" : 228 } }, { "from" : { "x" : 1701, "y" : 228 }, "to" : { "x" : 1743, "y" : 228 } } ], "endShape" : { "a" : { "x" : 1736, "y" : 232 }, "b" : { "x" : 1743, "y" : 228 }, "c" : { "x" : 1736, "y" : 224 }, "type" : "ARROW", "centre" : { "x" : 1736, "y" : 224 } }, "reactionShape" : { "c" : { "x" : 1701, "y" : 228 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1701, "y" : 228 } }, "inputs" : [ { "id" : 92903, "points" : [ { "x" : 1621, "y" : 229 } ] }, { "id" : 92904, "points" : [ { "x" : 1640, "y" : 257 } ] } ], "outputs" : [ { "id" : 92905 } ] }, { "id" : 92873, "reactomeId" : 10220833, "displayName" : "HDAC1, 2 bind MTA1, 2, 3 and RBBP4,7", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 444, "y" : 622 }, "minX" : 400, "maxX" : 478, "minY" : 616, "maxY" : 628, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 400, "y" : 623 }, "to" : { "x" : 444, "y" : 622 } }, { "from" : { "x" : 444, "y" : 622 }, "to" : { "x" : 478, "y" : 622 } } ], "endShape" : { "a" : { "x" : 471, "y" : 626 }, "b" : { "x" : 478, "y" : 622 }, "c" : { "x" : 471, "y" : 618 }, "type" : "ARROW", "centre" : { "x" : 471, "y" : 618 } }, "reactionShape" : { "c" : { "x" : 444, "y" : 622 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 444, "y" : 622 } }, "inputs" : [ { "id" : 92874, "points" : [ { "x" : 357, "y" : 625 } ], "stoichiometry" : 4 }, { "id" : 92875, "points" : [ { "x" : 367, "y" : 587 } ], "stoichiometry" : 2 }, { "id" : 92876, "points" : [ { "x" : 343, "y" : 674 } ], "stoichiometry" : 2 } ], "outputs" : [ { "id" : 92877 } ] }, { "id" : 92969, "reactomeId" : 10221280, "displayName" : "NuRD binds Ikaros family member proteins", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1590, "y" : 501 }, "minX" : 1550, "maxX" : 1635, "minY" : 490, "maxY" : 516, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1550, "y" : 516 }, "to" : { "x" : 1590, "y" : 501 } }, { "from" : { "x" : 1590, "y" : 501 }, "to" : { "x" : 1635, "y" : 490 } } ], "endShape" : { "a" : { "x" : 1629, "y" : 496 }, "b" : { "x" : 1635, "y" : 490 }, "c" : { "x" : 1627, "y" : 488 }, "type" : "ARROW", "centre" : { "x" : 1627, "y" : 488 } }, "reactionShape" : { "c" : { "x" : 1590, "y" : 501 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1590, "y" : 501 } }, "inputs" : [ { "id" : 92888, "points" : [ { "x" : 1130, "y" : 620 } ] }, { "id" : 92970, "points" : [ { "x" : 1511, "y" : 499 } ] } ], "outputs" : [ { "id" : 92971 } ] }, { "id" : 92936, "reactomeId" : 10221211, "displayName" : "CHD6-9-dependent ATP hydrolysis", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1316, "y" : 1015 }, "minX" : 1286, "maxX" : 1370, "minY" : 1009, "maxY" : 1021, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1286, "y" : 1016 }, "to" : { "x" : 1316, "y" : 1015 } }, { "from" : { "x" : 1316, "y" : 1015 }, "to" : { "x" : 1370, "y" : 1016 } } ], "reactionShape" : { "a" : { "x" : 1310, "y" : 1009 }, "b" : { "x" : 1322, "y" : 1021 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1316, "y" : 1015 } }, "inputs" : [ { "id" : 92937, "points" : [ { "x" : 1216, "y" : 942 } ] }, { "id" : 92938, "points" : [ { "x" : 1216, "y" : 1002 } ] }, { "id" : 92939, "points" : [ { "x" : 1200, "y" : 1038 } ] } ], "outputs" : [ { "id" : 92940, "points" : [ { "x" : 1427, "y" : 969 } ] }, { "id" : 92941, "points" : [ { "x" : 1440, "y" : 1002 } ] }, { "id" : 92942, "points" : [ { "x" : 1420, "y" : 1035 } ] }, { "id" : 92939, "points" : [ { "x" : 1200, "y" : 1052 }, { "x" : 1267, "y" : 1064 }, { "x" : 1352, "y" : 1062 } ] } ], "catalysts" : [ { "id" : 92943, "points" : [ { "x" : 1310, "y" : 952 } ] } ] }, { "id" : 92906, "reactomeId" : 10220900, "displayName" : "MBD3L2 binds MBD3 NuRD core complex", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 927, "y" : 782 }, "minX" : 897, "maxX" : 1003, "minY" : 776, "maxY" : 788, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 897, "y" : 780 }, "to" : { "x" : 927, "y" : 782 } }, { "from" : { "x" : 927, "y" : 782 }, "to" : { "x" : 1003, "y" : 779 } } ], "endShape" : { "a" : { "x" : 996, "y" : 783 }, "b" : { "x" : 1003, "y" : 779 }, "c" : { "x" : 996, "y" : 775 }, "type" : "ARROW", "centre" : { "x" : 996, "y" : 775 } }, "reactionShape" : { "c" : { "x" : 927, "y" : 782 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 927, "y" : 782 } }, "inputs" : [ { "id" : 92907, "points" : [ { "x" : 855, "y" : 772 } ] }, { "id" : 92908, "points" : [ { "x" : 813, "y" : 823 } ] } ], "outputs" : [ { "id" : 92909 } ] }, { "id" : 92910, "reactomeId" : 10221099, "displayName" : "MBD3L1 binds MBD2 NuRD core complex", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 942, "y" : 875 }, "minX" : 910, "maxX" : 1007, "minY" : 869, "maxY" : 881, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 910, "y" : 876 }, "to" : { "x" : 942, "y" : 875 } }, { "from" : { "x" : 942, "y" : 875 }, "to" : { "x" : 1007, "y" : 876 } } ], "endShape" : { "a" : { "x" : 1000, "y" : 880 }, "b" : { "x" : 1007, "y" : 876 }, "c" : { "x" : 1000, "y" : 872 }, "type" : "ARROW", "centre" : { "x" : 1000, "y" : 872 } }, "reactionShape" : { "c" : { "x" : 942, "y" : 875 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 942, "y" : 875 } }, "inputs" : [ { "id" : 92911, "points" : [ { "x" : 875, "y" : 911 } ] }, { "id" : 92912, "points" : [ { "x" : 825, "y" : 873 } ] } ], "outputs" : [ { "id" : 92913 } ] }, { "id" : 92878, "reactomeId" : 10220841, "displayName" : "PWWP2A, PWWP2B bind HDAC1,2:MTA1,MTA2,MTA3:RPPB4,RPPB7", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 644, "y" : 531 }, "minX" : 616, "maxX" : 673, "minY" : 525, "maxY" : 537, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 616, "y" : 531 }, "to" : { "x" : 644, "y" : 531 } }, { "from" : { "x" : 644, "y" : 531 }, "to" : { "x" : 673, "y" : 531 } } ], "endShape" : { "a" : { "x" : 666, "y" : 535 }, "b" : { "x" : 673, "y" : 531 }, "c" : { "x" : 666, "y" : 527 }, "type" : "ARROW", "centre" : { "x" : 666, "y" : 527 } }, "reactionShape" : { "c" : { "x" : 644, "y" : 531 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 644, "y" : 531 } }, "inputs" : [ { "id" : 92877, "points" : [ { "x" : 565, "y" : 595 } ] }, { "id" : 92879, "points" : [ { "x" : 593, "y" : 525 } ] } ], "outputs" : [ { "id" : 92880 } ] }, { "id" : 92881, "reactomeId" : 10220868, "displayName" : "MBD2, MBD3 and GATAD2A, GATAD2B bind core NuRD complex", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 739, "y" : 620 }, "minX" : 678, "maxX" : 785, "minY" : 614, "maxY" : 626, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 678, "y" : 621 }, "to" : { "x" : 739, "y" : 620 } }, { "from" : { "x" : 739, "y" : 620 }, "to" : { "x" : 785, "y" : 621 } } ], "endShape" : { "a" : { "x" : 778, "y" : 625 }, "b" : { "x" : 785, "y" : 621 }, "c" : { "x" : 778, "y" : 617 }, "type" : "ARROW", "centre" : { "x" : 778, "y" : 617 } }, "reactionShape" : { "c" : { "x" : 739, "y" : 620 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 739, "y" : 620 } }, "inputs" : [ { "id" : 92882, "points" : [ { "x" : 598, "y" : 663 } ] }, { "id" : 92883, "points" : [ { "x" : 686, "y" : 666 } ] }, { "id" : 92877, "points" : [ { "x" : 615, "y" : 622 } ] } ], "outputs" : [ { "id" : 92884 } ] }, { "id" : 92944, "reactomeId" : 10221221, "displayName" : "CHD8 and CHD7 bind CTCF", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1557, "y" : 1255 }, "minX" : 1525, "maxX" : 1609, "minY" : 1249, "maxY" : 1261, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1525, "y" : 1256 }, "to" : { "x" : 1557, "y" : 1255 } }, { "from" : { "x" : 1557, "y" : 1255 }, "to" : { "x" : 1609, "y" : 1253 } } ], "endShape" : { "a" : { "x" : 1602, "y" : 1257 }, "b" : { "x" : 1609, "y" : 1253 }, "c" : { "x" : 1602, "y" : 1249 }, "type" : "ARROW", "centre" : { "x" : 1602, "y" : 1249 } }, "reactionShape" : { "c" : { "x" : 1557, "y" : 1255 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1557, "y" : 1255 } }, "inputs" : [ { "id" : 92945, "points" : [ { "x" : 1483, "y" : 1256 } ] }, { "id" : 92946, "points" : [ { "x" : 1500, "y" : 1210 } ] } ], "outputs" : [ { "id" : 92947 } ] }, { "id" : 92914, "reactomeId" : 10221122, "displayName" : "ZNF827 and NR2C2,NR2F2 recruit NuRD to telomeric chromatin", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1601, "y" : 342 }, "minX" : 1561, "maxX" : 1662, "minY" : 336, "maxY" : 348, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1561, "y" : 341 }, "to" : { "x" : 1601, "y" : 342 } }, { "from" : { "x" : 1601, "y" : 342 }, "to" : { "x" : 1662, "y" : 342 } } ], "endShape" : { "a" : { "x" : 1655, "y" : 346 }, "b" : { "x" : 1662, "y" : 342 }, "c" : { "x" : 1655, "y" : 338 }, "type" : "ARROW", "centre" : { "x" : 1655, "y" : 338 } }, "reactionShape" : { "c" : { "x" : 1601, "y" : 342 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1601, "y" : 342 } }, "inputs" : [ { "id" : 92915, "points" : [ { "x" : 1466, "y" : 318 } ] }, { "id" : 92916, "points" : [ { "x" : 1417, "y" : 338 } ] }, { "id" : 92917, "points" : [ { "x" : 1446, "y" : 372 } ] }, { "id" : 92888, "points" : [ { "x" : 1130, "y" : 613 }, { "x" : 1350, "y" : 509 } ] } ], "outputs" : [ { "id" : 92918 } ] }, { "id" : 92885, "reactomeId" : 10220888, "displayName" : "CHD and CDK2AP subunits are recruited to NuRD", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1018, "y" : 627 }, "minX" : 984, "maxX" : 1061, "minY" : 621, "maxY" : 633, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 984, "y" : 628 }, "to" : { "x" : 1018, "y" : 627 } }, { "from" : { "x" : 1018, "y" : 627 }, "to" : { "x" : 1061, "y" : 627 } } ], "endShape" : { "a" : { "x" : 1054, "y" : 631 }, "b" : { "x" : 1061, "y" : 627 }, "c" : { "x" : 1054, "y" : 623 }, "type" : "ARROW", "centre" : { "x" : 1054, "y" : 623 } }, "reactionShape" : { "c" : { "x" : 1018, "y" : 627 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1018, "y" : 627 } }, "inputs" : [ { "id" : 92886, "points" : [ { "x" : 931, "y" : 678 } ] }, { "id" : 92887, "points" : [ { "x" : 1017, "y" : 671 } ] }, { "id" : 92884, "points" : [ { "x" : 942, "y" : 626 } ] } ], "outputs" : [ { "id" : 92888 } ] }, { "id" : 92948, "reactomeId" : 10221230, "displayName" : "CHD7 and CHD8 bind FAM124B", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1543, "y" : 1451 }, "minX" : 1517, "maxX" : 1601, "minY" : 1445, "maxY" : 1457, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1517, "y" : 1449 }, "to" : { "x" : 1543, "y" : 1451 } }, { "from" : { "x" : 1543, "y" : 1451 }, "to" : { "x" : 1601, "y" : 1451 } } ], "endShape" : { "a" : { "x" : 1594, "y" : 1455 }, "b" : { "x" : 1601, "y" : 1451 }, "c" : { "x" : 1594, "y" : 1447 }, "type" : "ARROW", "centre" : { "x" : 1594, "y" : 1447 } }, "reactionShape" : { "c" : { "x" : 1543, "y" : 1451 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1543, "y" : 1451 } }, "inputs" : [ { "id" : 92949, "points" : [ { "x" : 1469, "y" : 1444 } ] }, { "id" : 92950, "points" : [ { "x" : 1464, "y" : 1482 } ] }, { "id" : 92951, "points" : [ { "x" : 1457, "y" : 1418 } ] } ], "outputs" : [ { "id" : 92952 } ] }, { "id" : 92919, "reactomeId" : 10221127, "displayName" : "NuRD deacetylates telomeric nucleosomes", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1844, "y" : 337 }, "minX" : 1813, "maxX" : 1867, "minY" : 331, "maxY" : 343, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1813, "y" : 338 }, "to" : { "x" : 1844, "y" : 337 } }, { "from" : { "x" : 1844, "y" : 337 }, "to" : { "x" : 1867, "y" : 337 } } ], "reactionShape" : { "a" : { "x" : 1838, "y" : 331 }, "b" : { "x" : 1850, "y" : 343 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1844, "y" : 337 } }, "inputs" : [ { "id" : 92918, "points" : [ { "x" : 1791, "y" : 339 } ] }, { "id" : 92920, "points" : [ { "x" : 1797, "y" : 384 } ], "stoichiometry" : 2 } ], "outputs" : [ { "id" : 92921, "points" : [ { "x" : 1913, "y" : 334 } ] }, { "id" : 92922, "points" : [ { "x" : 1901, "y" : 383 } ], "stoichiometry" : 2 } ], "catalysts" : [ { "id" : 92918, "points" : [ { "x" : 1783, "y" : 307 }, { "x" : 1818, "y" : 290 } ] } ] }, { "id" : 92889, "reactomeId" : 10220890, "displayName" : "GATAD2A is SUMOylated", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 497, "y" : 828 }, "minX" : 491, "maxX" : 503, "minY" : 803, "maxY" : 853, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 498, "y" : 853 }, "to" : { "x" : 497, "y" : 828 } }, { "from" : { "x" : 497, "y" : 828 }, "to" : { "x" : 498, "y" : 803 } } ], "reactionShape" : { "a" : { "x" : 491, "y" : 822 }, "b" : { "x" : 503, "y" : 834 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 497, "y" : 828 } }, "inputs" : [ { "id" : 92890, "points" : [ { "x" : 533, "y" : 881 } ], "stoichiometry" : 2 }, { "id" : 92891, "points" : [ { "x" : 464, "y" : 875 } ] } ], "outputs" : [ { "id" : 92892, "points" : [ { "x" : 494, "y" : 764 } ] }, { "id" : 92893, "points" : [ { "x" : 533, "y" : 792 } ], "stoichiometry" : 2 } ], "catalysts" : [ { "id" : 92890, "points" : [ { "x" : 540, "y" : 881 } ] } ] }, { "id" : 92953, "reactomeId" : 10221234, "displayName" : "CHD8 binds WDR5", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1564, "y" : 1509 }, "minX" : 1512, "maxX" : 1608, "minY" : 1503, "maxY" : 1515, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1512, "y" : 1509 }, "to" : { "x" : 1564, "y" : 1509 } }, { "from" : { "x" : 1564, "y" : 1509 }, "to" : { "x" : 1608, "y" : 1510 } } ], "endShape" : { "a" : { "x" : 1601, "y" : 1514 }, "b" : { "x" : 1608, "y" : 1510 }, "c" : { "x" : 1601, "y" : 1506 }, "type" : "ARROW", "centre" : { "x" : 1601, "y" : 1506 } }, "reactionShape" : { "c" : { "x" : 1564, "y" : 1509 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1564, "y" : 1509 } }, "inputs" : [ { "id" : 92950, "points" : [ { "x" : 1472, "y" : 1500 } ] }, { "id" : 92954, "points" : [ { "x" : 1467, "y" : 1535 } ] } ], "outputs" : [ { "id" : 92955 } ] }, { "id" : 92923, "reactomeId" : 10221136, "displayName" : "PHF6 binds NuRD", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1529, "y" : 558 }, "minX" : 1501, "maxX" : 1565, "minY" : 552, "maxY" : 564, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1501, "y" : 557 }, "to" : { "x" : 1529, "y" : 558 } }, { "from" : { "x" : 1529, "y" : 558 }, "to" : { "x" : 1565, "y" : 559 } } ], "endShape" : { "a" : { "x" : 1558, "y" : 563 }, "b" : { "x" : 1565, "y" : 559 }, "c" : { "x" : 1558, "y" : 555 }, "type" : "ARROW", "centre" : { "x" : 1558, "y" : 555 } }, "reactionShape" : { "c" : { "x" : 1529, "y" : 558 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1529, "y" : 558 } }, "inputs" : [ { "id" : 92888, "points" : [ { "x" : 1130, "y" : 622 } ] }, { "id" : 92924, "points" : [ { "x" : 1471, "y" : 581 } ] } ], "outputs" : [ { "id" : 92925 } ] }, { "id" : 92956, "reactomeId" : 10176972, "displayName" : "CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1548, "y" : 1569 }, "minX" : 1511, "maxX" : 1599, "minY" : 1563, "maxY" : 1575, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 1511, "y" : 1564 }, "to" : { "x" : 1548, "y" : 1569 } }, { "from" : { "x" : 1548, "y" : 1569 }, "to" : { "x" : 1599, "y" : 1570 } } ], "endShape" : { "a" : { "x" : 1592, "y" : 1574 }, "b" : { "x" : 1599, "y" : 1570 }, "c" : { "x" : 1592, "y" : 1566 }, "type" : "ARROW", "centre" : { "x" : 1592, "y" : 1566 } }, "reactionShape" : { "c" : { "x" : 1548, "y" : 1569 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 1548, "y" : 1569 } }, "inputs" : [ { "id" : 92950, "points" : [ { "x" : 1457, "y" : 1511 } ] }, { "id" : 92957, "points" : [ { "x" : 1461, "y" : 1588 } ] } ], "outputs" : [ { "id" : 92958 } ] }, { "id" : 92959, "reactomeId" : 10221246, "displayName" : "NuRD binds TCF19 at FBP1 gene", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 902, "y" : 418 }, "minX" : 880, "maxX" : 923, "minY" : 396, "maxY" : 437, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 923, "y" : 437 }, "to" : { "x" : 902, "y" : 418 } }, { "from" : { "x" : 902, "y" : 418 }, "to" : { "x" : 880, "y" : 396 } } ], "endShape" : { "a" : { "x" : 888, "y" : 398 }, "b" : { "x" : 880, "y" : 396 }, "c" : { "x" : 882, "y" : 404 }, "type" : "ARROW", "centre" : { "x" : 882, "y" : 404 } }, "reactionShape" : { "c" : { "x" : 902, "y" : 418 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 902, "y" : 418 } }, "inputs" : [ { "id" : 92960, "points" : [ { "x" : 976, "y" : 563 } ] }, { "id" : 92888, "points" : [ { "x" : 1081, "y" : 610 } ] }, { "id" : 92961, "points" : [ { "x" : 898, "y" : 504 } ] } ], "outputs" : [ { "id" : 92962 } ] }, { "id" : 92894, "reactomeId" : 10220856, "displayName" : "GATAD2B is SUMOylated", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 612, "y" : 828 }, "minX" : 606, "maxX" : 618, "minY" : 812, "maxY" : 853, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 616, "y" : 853 }, "to" : { "x" : 612, "y" : 828 } }, { "from" : { "x" : 612, "y" : 828 }, "to" : { "x" : 610, "y" : 812 } } ], "reactionShape" : { "a" : { "x" : 606, "y" : 822 }, "b" : { "x" : 618, "y" : 834 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 612, "y" : 828 } }, "inputs" : [ { "id" : 92890, "points" : [ { "x" : 579, "y" : 881 } ] }, { "id" : 92895, "points" : [ { "x" : 651, "y" : 881 } ] } ], "outputs" : [ { "id" : 92893, "points" : [ { "x" : 581, "y" : 796 } ] }, { "id" : 92896, "points" : [ { "x" : 620, "y" : 768 } ] } ], "catalysts" : [ { "id" : 92890, "points" : [ { "x" : 570, "y" : 881 } ] } ] }, { "id" : 92926, "reactomeId" : 10221173, "displayName" : "CHD1 and CHD2 bind H3K4me3 nucleosomes", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 434, "y" : 1249 }, "minX" : 408, "maxX" : 494, "minY" : 1243, "maxY" : 1255, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 408, "y" : 1255 }, "to" : { "x" : 434, "y" : 1249 } }, { "from" : { "x" : 434, "y" : 1249 }, "to" : { "x" : 494, "y" : 1248 } } ], "endShape" : { "a" : { "x" : 487, "y" : 1252 }, "b" : { "x" : 494, "y" : 1248 }, "c" : { "x" : 487, "y" : 1244 }, "type" : "ARROW", "centre" : { "x" : 487, "y" : 1244 } }, "reactionShape" : { "c" : { "x" : 434, "y" : 1249 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 434, "y" : 1249 } }, "inputs" : [ { "id" : 92927, "points" : [ { "x" : 373, "y" : 1277 } ] }, { "id" : 92928, "points" : [ { "x" : 374, "y" : 1241 } ] } ], "outputs" : [ { "id" : 92929 } ] } ], "compartments" : [ { "id" : 92993, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1190, "y" : 892 }, "minX" : 0, "maxX" : 2380, "minY" : 0, "maxY" : 1785, "prop" : { "x" : 0, "y" : 0, "width" : 2380, "height" : 1785 }, "textPosition" : { "x" : 73, "y" : 388 }, "insets" : { "x" : 10, "y" : 10, "width" : 2360, "height" : 1765 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 92972, 93000 ] }, { "id" : 93000, "reactomeId" : 17957, "displayName" : "endoplasmic reticulum lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 873, "y" : 90 }, "minX" : 762, "maxX" : 985, "minY" : 57, "maxY" : 124, "prop" : { "x" : 762, "y" : 57, "width" : 223, "height" : 67 }, "textPosition" : { "x" : 775, "y" : 68 }, "insets" : { "x" : 772, "y" : 67, "width" : 203, "height" : 47 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 } }, { "id" : 92972, "reactomeId" : 7660, "displayName" : "nucleoplasm", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1197, "y" : 913 }, "minX" : 188, "maxX" : 2206, "minY" : 158, "maxY" : 1669, "prop" : { "x" : 188, "y" : 158, "width" : 2018, "height" : 1511 }, "textPosition" : { "x" : 891, "y" : 1055 }, "insets" : { "x" : 198, "y" : 168, "width" : 1998, "height" : 1491 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 92875, 92874, 92873, 92876, 92877, 92878, 92879, 92880, 92881, 92883, 92884, 92885, 92886, 92887, 92888, 92889, 92890, 92891, 92892, 92893, 92894, 92895, 92896, 92882, 93003, 93004, 92897, 92898, 92899, 92900, 92901, 92902, 92905, 92903, 92904, 92906, 92907, 92908, 92909, 92910, 92911, 92912, 92913, 92914, 92915, 92916, 92917, 92918, 92919, 92920, 92921, 92922, 92923, 92924, 92925, 92926, 92928, 92929, 92930, 92931, 92932, 92933, 92934, 92935, 92927, 92936, 92943, 92941, 92942, 92937, 92938, 92940, 92939, 93005, 92944, 92945, 92946, 92947, 92948, 92949, 92950, 92951, 92952, 92953, 92954, 92955, 92957, 92958, 92956, 92959, 92960, 92961, 92962, 92963, 92964, 92965, 92966, 92967, 92968, 92969, 92970, 92971 ] } ], "notes" : [ ], "links" : [ { "id" : 93003, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 533, "y" : 716 }, "minX" : 523, "maxX" : 543, "minY" : 710, "maxY" : 722, "segments" : [ { "from" : { "x" : 523, "y" : 721 }, "to" : { "x" : 543, "y" : 712 } } ], "reactionShape" : { "a" : { "x" : 527, "y" : 710 }, "b" : { "x" : 539, "y" : 722 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 533, "y" : 716 } }, "inputs" : [ { "id" : 92892 } ], "outputs" : [ { "id" : 92882 } ] }, { "id" : 93005, "renderableClass" : "EntitySetAndEntitySetLink", "position" : { "x" : 1371, "y" : 1095 }, "minX" : 1315, "maxX" : 1427, "minY" : 952, "maxY" : 1239, "segments" : [ { "from" : { "x" : 1427, "y" : 1239 }, "to" : { "x" : 1315, "y" : 952 } } ], "reactionShape" : { "a" : { "x" : 1365, "y" : 1089 }, "b" : { "x" : 1377, "y" : 1101 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1371, "y" : 1095 } }, "inputs" : [ { "id" : 92945 } ], "outputs" : [ { "id" : 92943 } ] }, { "id" : 93004, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 593, "y" : 718 }, "minX" : 584, "maxX" : 602, "minY" : 712, "maxY" : 725, "segments" : [ { "from" : { "x" : 602, "y" : 725 }, "to" : { "x" : 584, "y" : 712 } } ], "reactionShape" : { "a" : { "x" : 587, "y" : 712 }, "b" : { "x" : 599, "y" : 724 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 593, "y" : 718 } }, "inputs" : [ { "id" : 92896 } ], "outputs" : [ { "id" : 92882 } ] } ], "shadows" : [ { "id" : 93008, "reactomeId" : 10225539, "displayName" : "CHD1 and CHD2 subfamily", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 556, "y" : 1349 }, "minX" : 279, "maxX" : 834, "minY" : 1202, "maxY" : 1497, "prop" : { "x" : 279, "y" : 1202, "width" : 555, "height" : 295 }, "points" : [ { "x" : 279, "y" : 1202 }, { "x" : 834, "y" : 1202 }, { "x" : 834, "y" : 1497 }, { "x" : 279, "y" : 1497 } ], "colour" : "#008000" }, { "id" : 93007, "reactomeId" : 10225531, "displayName" : "CHD3, CHD4, CHD5 subfamily", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 1150, "y" : 620 }, "minX" : 251, "maxX" : 2049, "minY" : 195, "maxY" : 1045, "prop" : { "x" : 251, "y" : 195, "width" : 1798, "height" : 703 }, "points" : [ { "x" : 251, "y" : 195 }, { "x" : 2049, "y" : 195 }, { "x" : 2049, "y" : 1045 }, { "x" : 251, "y" : 1045 } ], "colour" : "#dc3912" }, { "id" : 93006, "reactomeId" : 10224657, "displayName" : "CHD6, CHD7, CHD8, CHD9 subfamily", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 1419, "y" : 1261 }, "minX" : 1121, "maxX" : 1717, "minY" : 898, "maxY" : 1624, "prop" : { "x" : 1121, "y" : 1045, "width" : 596, "height" : 579 }, "points" : [ { "x" : 1121, "y" : 898 }, { "x" : 1717, "y" : 898 }, { "x" : 1717, "y" : 1624 }, { "x" : 1121, "y" : 1624 } ], "colour" : "#4684ee" } ], "minX" : 0, "maxX" : 2380, "minY" : 0, "maxY" : 1785, "disease" : false }