{
  "dbId" : 10225007,
  "stId" : "R-RNO-8853659",
  "speciesName" : "Rattus norvegicus",
  "nodes" : [ {
    "dbId" : 10199451,
    "stId" : "R-RNO-8855748",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes:SRC-1,RAP1GAP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34116 ],
    "parents" : [ ],
    "children" : [ 10182431, 10199449 ]
  }, {
    "dbId" : 10199449,
    "stId" : "R-RNO-8855753",
    "displayName" : "SRC-1, RAP1GAP [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 34115 ],
    "parents" : [ 10199451 ],
    "children" : [ 10135703, 548926 ]
  }, {
    "dbId" : 10224791,
    "stId" : "R-RNO-5673001",
    "displayName" : "RAF/MAP kinase cascade",
    "schemaClass" : "Pathway",
    "speciesId" : 48895,
    "diagramIds" : [ 34123 ]
  }, {
    "dbId" : 10135703,
    "stId" : "R-RNO-392493",
    "displayName" : "Rap1gap [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "F1LV89",
    "standardIdentifier" : "uniprot:F1LV89",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Rap1gap" ],
    "parents" : [ 10199449 ],
    "children" : [ ]
  }, {
    "dbId" : 10175370,
    "stId" : "R-RNO-425833",
    "displayName" : "Protein kinase A catalytic subunit [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 48895,
    "diagramIds" : [ 34071 ],
    "parents" : [ ],
    "children" : [ 10112079, 10112073 ]
  }, {
    "dbId" : 10180750,
    "stId" : "R-RNO-170963",
    "displayName" : "Frs2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 34076 ],
    "identifier" : "D4A244",
    "standardIdentifier" : "uniprot:D4A244",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Frs2", "Frs2_predicted", "rCG_48891" ],
    "parents" : [ 10199400 ],
    "children" : [ ]
  }, {
    "dbId" : 10126978,
    "stId" : "R-RNO-204819",
    "displayName" : "Grb7 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q9QZC5",
    "standardIdentifier" : "uniprot:Q9QZC5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Grb7" ],
    "parents" : [ 10198985 ],
    "children" : [ ]
  }, {
    "dbId" : 10199482,
    "stId" : "R-RNO-8855085",
    "displayName" : "Pdlim7 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q9Z1Z9",
    "standardIdentifier" : "uniprot:Q9Z1Z9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pdlim7" ],
    "parents" : [ 10199488 ],
    "children" : [ ]
  }, {
    "dbId" : 10108606,
    "stId" : "R-RNO-74789",
    "displayName" : "Pik3r1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q63787",
    "standardIdentifier" : "uniprot:Q63787",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pik3r1" ],
    "parents" : [ 10112931 ],
    "children" : [ ]
  }, {
    "dbId" : 10198975,
    "stId" : "R-RNO-8854400",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34083 ],
    "parents" : [ ],
    "children" : [ 10108630, 10182431 ]
  }, {
    "dbId" : 10199486,
    "stId" : "R-RNO-3006448",
    "displayName" : "Shc3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "O70143",
    "standardIdentifier" : "uniprot:O70143",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Shc3", "Nshc", "Shcc" ],
    "parents" : [ 10199488 ],
    "children" : [ ]
  }, {
    "dbId" : 10199484,
    "stId" : "R-RNO-198754",
    "displayName" : "MAPK7 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "P0C865",
    "standardIdentifier" : "uniprot:P0C865",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10199488 ],
    "children" : [ ]
  }, {
    "dbId" : 10108594,
    "stId" : "R-RNO-74686",
    "displayName" : "Grb2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 34092 ],
    "identifier" : "P62994",
    "standardIdentifier" : "uniprot:P62994",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Grb2", "Ash" ],
    "parents" : [ 10199011, 10199013, 10108599 ],
    "children" : [ ]
  }, {
    "dbId" : 10108338,
    "stId" : "R-RNO-110009",
    "displayName" : "Grb10 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "P0CE43",
    "standardIdentifier" : "uniprot:P0CE43",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Grb10" ],
    "parents" : [ 10198985 ],
    "children" : [ ]
  }, {
    "dbId" : 10108599,
    "stId" : "R-RNO-109797",
    "displayName" : "GRB2-1:SOS1 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34087 ],
    "parents" : [ 10182437, 10182435 ],
    "children" : [ 10108594, 10108597 ]
  }, {
    "dbId" : 10108597,
    "stId" : "R-RNO-64847",
    "displayName" : "Sos1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "D4A3T0",
    "standardIdentifier" : "uniprot:D4A3T0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Sos1", "rCG_62427" ],
    "parents" : [ 10108599 ],
    "children" : [ ]
  }, {
    "dbId" : 10190260,
    "stId" : "R-RNO-6794277",
    "displayName" : "Shank3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q9JLU4",
    "standardIdentifier" : "uniprot:Q9JLU4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Shank3", "Prosap2" ],
    "parents" : [ 10199488 ],
    "children" : [ ]
  }, {
    "dbId" : 548926,
    "stId" : "R-RNO-548926",
    "displayName" : "SRC_RAT [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q9WUD9",
    "standardIdentifier" : "uniprot:Q9WUD9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Src" ],
    "parents" : [ 10199449 ],
    "children" : [ ]
  }, {
    "dbId" : 10112931,
    "stId" : "R-RNO-391342",
    "displayName" : "PI3K-regulatory subunits [cytosol]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 48895,
    "parents" : [ 10134622, 10134624, 10112933 ],
    "children" : [ 10108606, 10112929, 10108609 ]
  }, {
    "dbId" : 10112929,
    "stId" : "R-RNO-205223",
    "displayName" : "Pik3r3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q63789",
    "standardIdentifier" : "uniprot:Q63789",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pik3r3" ],
    "parents" : [ 10112931 ],
    "children" : [ ]
  }, {
    "dbId" : 10108327,
    "stId" : "R-RNO-57528",
    "displayName" : "Irs2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "F1MAL5",
    "standardIdentifier" : "uniprot:F1MAL5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Irs2", "rCG_43183" ],
    "parents" : [ 10199488 ],
    "children" : [ ]
  }, {
    "dbId" : 10127012,
    "stId" : "R-RNO-204823",
    "displayName" : "Dok2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "A0A8I6ALT5",
    "standardIdentifier" : "uniprot:A0A8I6ALT5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dok2" ],
    "parents" : [ 10199416 ],
    "children" : [ ]
  }, {
    "dbId" : 10112933,
    "stId" : "R-RNO-198379",
    "displayName" : "PI3K alpha [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10143211 ],
    "children" : [ 10112931, 10108617 ]
  }, {
    "dbId" : 10199003,
    "stId" : "R-RNO-8853798",
    "displayName" : "RET:GFRA4:PSPN [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34057 ],
    "parents" : [ 10199005 ],
    "children" : [ 10182419, 10199001 ]
  }, {
    "dbId" : 10199001,
    "stId" : "R-RNO-8855751",
    "displayName" : "RET:GFRA4 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34055 ],
    "parents" : [ 10199003 ],
    "children" : [ 10182423, 10198979 ]
  }, {
    "dbId" : 10199007,
    "stId" : "R-RNO-8853818",
    "displayName" : "2x RET:GFRA:GDNF complexes [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34063 ],
    "parents" : [ ],
    "children" : [ 10199005 ]
  }, {
    "dbId" : 10182367,
    "stId" : "R-RNO-434903",
    "displayName" : "Artn [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 34052 ],
    "identifier" : "Q6AYE8",
    "standardIdentifier" : "uniprot:Q6AYE8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Artn" ],
    "parents" : [ 10198995, 10182392 ],
    "children" : [ ]
  }, {
    "dbId" : 10199005,
    "stId" : "R-RNO-8853817",
    "displayName" : "RET:GFRA:GDNF complexes [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 34062 ],
    "parents" : [ 10199007 ],
    "children" : [ 10198999, 10198995, 10199003 ]
  }, {
    "dbId" : 10198995,
    "stId" : "R-RNO-8853795",
    "displayName" : "RET:GFRA1,GFRA3:ARTN [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34053 ],
    "parents" : [ 10199005 ],
    "children" : [ 10198981, 10182367 ]
  }, {
    "dbId" : 10198999,
    "stId" : "R-RNO-8853805",
    "displayName" : "RET:GFRA1,GFRA2:GDNF,NRTN [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34049 ],
    "parents" : [ 10199005 ],
    "children" : [ 10198997, 10182400 ]
  }, {
    "dbId" : 10108630,
    "stId" : "R-RNO-74680",
    "displayName" : "Shc1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 34082 ],
    "identifier" : "Q5M824",
    "standardIdentifier" : "uniprot:Q5M824",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Shc1" ],
    "parents" : [ 10198975 ],
    "children" : [ ]
  }, {
    "dbId" : 10198997,
    "stId" : "R-RNO-8855759",
    "displayName" : "RET:GFRA1,GFRA2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34048 ],
    "parents" : [ 10198999 ],
    "children" : [ 10182406, 10198979 ]
  }, {
    "dbId" : 10198987,
    "stId" : "R-RNO-8854768",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB10 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34110 ],
    "parents" : [ ],
    "children" : [ 10182431, 10198985 ]
  }, {
    "dbId" : 10125512,
    "stId" : "R-RNO-202320",
    "displayName" : "PLCG1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 34112 ],
    "identifier" : "P10686",
    "standardIdentifier" : "uniprot:P10686",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Plcg1" ],
    "parents" : [ 10198991 ],
    "children" : [ ]
  }, {
    "dbId" : 10198985,
    "stId" : "R-RNO-8854773",
    "displayName" : "GRB7,GRB10 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 34109 ],
    "parents" : [ 10198987 ],
    "children" : [ 10126978, 10108338 ]
  }, {
    "dbId" : 10108617,
    "stId" : "R-RNO-74787",
    "displayName" : "Pik3ca [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "A0A0G2K344",
    "standardIdentifier" : "uniprot:A0A0G2K344",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pik3ca" ],
    "parents" : [ 10112933 ],
    "children" : [ ]
  }, {
    "dbId" : 10198991,
    "stId" : "R-RNO-8854776",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes:PLCG1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34113 ],
    "parents" : [ ],
    "children" : [ 10182431, 10125512 ]
  }, {
    "dbId" : 10198979,
    "stId" : "R-RNO-8853797",
    "displayName" : "RET [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 34060 ],
    "identifier" : "G3V9H8",
    "standardIdentifier" : "uniprot:G3V9H8",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10198997, 10198981, 10199001 ],
    "children" : [ ]
  }, {
    "dbId" : 10199490,
    "stId" : "R-RNO-8855914",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes:RET interactors [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34074 ],
    "parents" : [ ],
    "children" : [ 10199488, 10182431 ]
  }, {
    "dbId" : 10108609,
    "stId" : "R-RNO-74791",
    "displayName" : "Pik3r2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q63788",
    "standardIdentifier" : "uniprot:Q63788",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pik3r2" ],
    "parents" : [ 10112931 ],
    "children" : [ ]
  }, {
    "dbId" : 10199488,
    "stId" : "R-RNO-8855913",
    "displayName" : "RET interactors [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 34073 ],
    "parents" : [ 10199490 ],
    "children" : [ 10190260, 10112196, 10108327, 10199484, 10199486, 10199482 ]
  }, {
    "dbId" : 10198981,
    "stId" : "R-RNO-8855745",
    "displayName" : "RET:GFRA1,GFRA3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34051 ],
    "parents" : [ 10198995 ],
    "children" : [ 10198979, 10182379 ]
  }, {
    "dbId" : 10112196,
    "stId" : "R-RNO-58196",
    "displayName" : "PRKCA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "P05696",
    "standardIdentifier" : "uniprot:P05696",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10199488 ],
    "children" : [ ]
  }, {
    "dbId" : 10182392,
    "stId" : "R-RNO-8855755",
    "displayName" : "p-5Y-RET:GFRA1,GFRA3:ARTN [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10182429 ],
    "children" : [ 10182390, 10182367 ]
  }, {
    "dbId" : 10182398,
    "stId" : "R-RNO-434904",
    "displayName" : "Nrtn [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q811Q5",
    "standardIdentifier" : "uniprot:Q811Q5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Nrtn" ],
    "parents" : [ 10182400 ],
    "children" : [ ]
  }, {
    "dbId" : 10199036,
    "stId" : "R-RNO-8854900",
    "displayName" : "p-5Y-RET:GDNF:GFRA complexes with and without p-SHC1 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 34093 ],
    "parents" : [ ],
    "children" : [ 10182433, 10182431 ]
  }, {
    "dbId" : 10199027,
    "stId" : "R-RNO-8855302",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34100 ],
    "parents" : [ 10199324, 10199396 ],
    "children" : [ 10199015, 10199025 ]
  }, {
    "dbId" : 10127344,
    "stId" : "R-RNO-508239",
    "displayName" : "Gab2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q9EQH1",
    "standardIdentifier" : "uniprot:Q9EQH1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Gab2" ],
    "parents" : [ 10199017 ],
    "children" : [ ]
  }, {
    "dbId" : 10199025,
    "stId" : "R-RNO-8855296",
    "displayName" : "p-5Y-GAB1,p-5Y-GAB2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "parents" : [ 10199027 ],
    "children" : [ 10199023, 10120266 ]
  }, {
    "dbId" : 10182390,
    "stId" : "R-RNO-8855731",
    "displayName" : "p-5Y-RET:GFRA1,GFRA3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10182392 ],
    "children" : [ 10182388, 10182379 ]
  }, {
    "dbId" : 10182388,
    "stId" : "R-RNO-8854162",
    "displayName" : "phospho-p-5Y-RET [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "G3V9H8",
    "standardIdentifier" : "uniprot:G3V9H8",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10182390, 10182408, 10182425 ],
    "children" : [ ]
  }, {
    "dbId" : 10182379,
    "stId" : "R-RNO-8853799",
    "displayName" : "GFRA1,GFRA3 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 34059 ],
    "parents" : [ 10198981, 10182390 ],
    "children" : [ 10182373, 10182377 ]
  }, {
    "dbId" : 10199019,
    "stId" : "R-RNO-8855090",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34097 ],
    "parents" : [ ],
    "children" : [ 10199015, 10199017 ]
  }, {
    "dbId" : 10143211,
    "stId" : "R-RNO-508248",
    "displayName" : "p85-containing Class 1A PI3Ks [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 34103 ],
    "parents" : [ 10199324 ],
    "children" : [ 10112933, 10134624, 10134622 ]
  }, {
    "dbId" : 10182377,
    "stId" : "R-RNO-8853796",
    "displayName" : "GFRA3 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "F7F1M3",
    "standardIdentifier" : "uniprot:F7F1M3",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10182379 ],
    "children" : [ ]
  }, {
    "dbId" : 10199017,
    "stId" : "R-RNO-8855092",
    "displayName" : "GAB1,GAB2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 34096 ],
    "parents" : [ 10199019 ],
    "children" : [ 10127344, 10110978 ]
  }, {
    "dbId" : 10199023,
    "stId" : "R-RNO-8855574",
    "displayName" : "phospho-Gab2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q9EQH1",
    "standardIdentifier" : "uniprot:Q9EQH1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Gab2" ],
    "parents" : [ 10199025 ],
    "children" : [ ]
  }, {
    "dbId" : 10197741,
    "stId" : "R-RNO-74763",
    "displayName" : "Dok1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q4QQV2",
    "standardIdentifier" : "uniprot:Q4QQV2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dok1" ],
    "parents" : [ 10199416 ],
    "children" : [ ]
  }, {
    "dbId" : 10199011,
    "stId" : "R-RNO-8854978",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10199015 ],
    "children" : [ 10182433, 10108594 ]
  }, {
    "dbId" : 10199015,
    "stId" : "R-RNO-8854907",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 34094 ],
    "parents" : [ 10199027, 10199019 ],
    "children" : [ 10199013, 10199011 ]
  }, {
    "dbId" : 10182373,
    "stId" : "R-RNO-375067",
    "displayName" : "Gfra1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q62997",
    "standardIdentifier" : "uniprot:Q62997",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Gfra1", "Gdnfra", "Retl1", "Trnr1" ],
    "parents" : [ 10182379, 10182406 ],
    "children" : [ ]
  }, {
    "dbId" : 10199013,
    "stId" : "R-RNO-8854983",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10199015 ],
    "children" : [ 10108594, 10182431 ]
  }, {
    "dbId" : 10182427,
    "stId" : "R-RNO-8855729",
    "displayName" : "p-5Y-RET:GFRA4:PSPN [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10182429 ],
    "children" : [ 10182419, 10182425 ]
  }, {
    "dbId" : 10182425,
    "stId" : "R-RNO-8855764",
    "displayName" : "p-5Y-RET:GFRA4 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10182427 ],
    "children" : [ 10182388, 10182423 ]
  }, {
    "dbId" : 10182431,
    "stId" : "R-RNO-8854160",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34067 ],
    "parents" : [ 10198987, 10198991, 10199490, 10199400, 10199013, 10199036, 10199418, 10199451, 10198975, 10182433, 10182437 ],
    "children" : [ 10182429 ]
  }, {
    "dbId" : 10182429,
    "stId" : "R-RNO-8855746",
    "displayName" : "p-5Y-RET:GFRA:GDNF complexes [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "parents" : [ 10182431 ],
    "children" : [ 10182392, 10182410, 10182427 ]
  }, {
    "dbId" : 451713,
    "stId" : "R-RNO-451713",
    "displayName" : "p110 beta [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q9Z1L0",
    "standardIdentifier" : "uniprot:Q9Z1L0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pik3cb" ],
    "parents" : [ 10134624 ],
    "children" : [ ]
  }, {
    "dbId" : 10199324,
    "stId" : "R-RNO-8855523",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34104 ],
    "parents" : [ ],
    "children" : [ 10199027, 10143211 ]
  }, {
    "dbId" : 10182419,
    "stId" : "R-RNO-434907",
    "displayName" : "Pspn [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 34056 ],
    "identifier" : "O70301",
    "standardIdentifier" : "uniprot:O70301",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pspn" ],
    "parents" : [ 10199003, 10182427 ],
    "children" : [ ]
  }, {
    "dbId" : 10182423,
    "stId" : "R-RNO-434900",
    "displayName" : "Gfra4 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 34120 ],
    "identifier" : "Q9EPI2",
    "standardIdentifier" : "uniprot:Q9EPI2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Gfra4" ],
    "parents" : [ 10199001, 10182425 ],
    "children" : [ ]
  }, {
    "dbId" : 10182410,
    "stId" : "R-RNO-8855757",
    "displayName" : "p-5Y-RET:GFRA1,GFRA2:GDNF,NRTN [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10182429 ],
    "children" : [ 10182400, 10182408 ]
  }, {
    "dbId" : 10182408,
    "stId" : "R-RNO-8855728",
    "displayName" : "p-5Y-RET:GFRA1,GFRA2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10182410 ],
    "children" : [ 10182388, 10182406 ]
  }, {
    "dbId" : 10142217,
    "stId" : "R-RNO-912321",
    "displayName" : "phospho-Shc1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q5M824",
    "standardIdentifier" : "uniprot:Q5M824",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Shc1" ],
    "parents" : [ 10182433 ],
    "children" : [ ]
  }, {
    "dbId" : 10110978,
    "stId" : "R-RNO-179795",
    "displayName" : "Gab1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "D3ZAL7",
    "standardIdentifier" : "uniprot:D3ZAL7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Gab1" ],
    "parents" : [ 10199017 ],
    "children" : [ ]
  }, {
    "dbId" : 10182400,
    "stId" : "R-RNO-8853802",
    "displayName" : "GDNF,NRTN [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 34047 ],
    "parents" : [ 10198999, 10182410 ],
    "children" : [ 420336, 10182398 ]
  }, {
    "dbId" : 10182406,
    "stId" : "R-RNO-8853803",
    "displayName" : "GFRA1, GFRA2 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 34118 ],
    "parents" : [ 10198997, 10182408 ],
    "children" : [ 10182404, 10182373 ]
  }, {
    "dbId" : 10182404,
    "stId" : "R-RNO-434901",
    "displayName" : "Gfra2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "O35977",
    "standardIdentifier" : "uniprot:O35977",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Gfra2" ],
    "parents" : [ 10182406 ],
    "children" : [ ]
  }, {
    "dbId" : 10182435,
    "stId" : "R-RNO-8854399",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34088 ],
    "parents" : [ ],
    "children" : [ 10108599, 10182433 ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34065, 34099, 34069 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 34066, 34101, 34070 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10182433,
    "stId" : "R-RNO-8854980",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34085 ],
    "parents" : [ 10199011, 10199036, 10182435 ],
    "children" : [ 10182431, 10142217 ]
  }, {
    "dbId" : 10182437,
    "stId" : "R-RNO-8854903",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34090 ],
    "parents" : [ ],
    "children" : [ 10108599, 10182431 ]
  }, {
    "dbId" : 10134622,
    "stId" : "R-RNO-508241",
    "displayName" : "PI3K delta [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10143211 ],
    "children" : [ 10112931, 10134620 ]
  }, {
    "dbId" : 10134620,
    "stId" : "R-RNO-392274",
    "displayName" : "Pik3cd [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "A0A8I5Y949",
    "standardIdentifier" : "uniprot:A0A8I5Y949",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Pik3cd" ],
    "parents" : [ 10134622 ],
    "children" : [ ]
  }, {
    "dbId" : 10120266,
    "stId" : "R-RNO-180344",
    "displayName" : "phospho-Gab1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "D3ZAL7",
    "standardIdentifier" : "uniprot:D3ZAL7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Gab1" ],
    "parents" : [ 10199025 ],
    "children" : [ ]
  }, {
    "dbId" : 10112073,
    "stId" : "R-RNO-57844",
    "displayName" : "PRKACA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "P27791",
    "standardIdentifier" : "uniprot:P27791",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Prkaca" ],
    "parents" : [ 10175370 ],
    "children" : [ ]
  }, {
    "dbId" : 10112079,
    "stId" : "R-RNO-57846",
    "displayName" : "PRKACB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "P68182",
    "standardIdentifier" : "uniprot:P68182",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Prkacb", "Pkacb" ],
    "parents" : [ 10175370 ],
    "children" : [ ]
  }, {
    "dbId" : 10199418,
    "stId" : "R-RNO-8855573",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes:DOK1,DOK2,DOK4,DOK5,DOK6 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34080 ],
    "parents" : [ ],
    "children" : [ 10182431, 10199416 ]
  }, {
    "dbId" : 10199416,
    "stId" : "R-RNO-8855619",
    "displayName" : "DOK1,DOK2,DOK4,DOK5,DOK6 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 34079 ],
    "parents" : [ 10199418 ],
    "children" : [ 10127012, 10199414, 10199410, 10197741, 10199406 ]
  }, {
    "dbId" : 10199410,
    "stId" : "R-RNO-8847605",
    "displayName" : "Dok5 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "B2RZ51",
    "standardIdentifier" : "uniprot:B2RZ51",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dok5" ],
    "parents" : [ 10199416 ],
    "children" : [ ]
  }, {
    "dbId" : 10199414,
    "stId" : "R-RNO-8855620",
    "displayName" : "Dok6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "F1M038",
    "standardIdentifier" : "uniprot:F1M038",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dok6" ],
    "parents" : [ 10199416 ],
    "children" : [ ]
  }, {
    "dbId" : 10116968,
    "stId" : "R-RNO-162563",
    "displayName" : "PTPN11 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 34106 ],
    "identifier" : "P41499",
    "standardIdentifier" : "uniprot:P41499",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ptpn11" ],
    "parents" : [ 10199396 ],
    "children" : [ ]
  }, {
    "dbId" : 10199400,
    "stId" : "R-RNO-8855579",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes:FRS2 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34077 ],
    "parents" : [ ],
    "children" : [ 10180750, 10182431 ]
  }, {
    "dbId" : 10199406,
    "stId" : "R-RNO-8847701",
    "displayName" : "Dok4 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "F7FET5",
    "standardIdentifier" : "uniprot:F7FET5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dok4" ],
    "parents" : [ 10199416 ],
    "children" : [ ]
  }, {
    "dbId" : 420336,
    "stId" : "R-RNO-420336",
    "displayName" : "GDNF [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q07731",
    "standardIdentifier" : "uniprot:Q07731",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Gdnf" ],
    "parents" : [ 10182400 ],
    "children" : [ ]
  }, {
    "dbId" : 10134624,
    "stId" : "R-RNO-437110",
    "displayName" : "PI3K beta [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10143211 ],
    "children" : [ 10112931, 451713 ]
  }, {
    "dbId" : 10199396,
    "stId" : "R-RNO-8855762",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:PTPN11 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 34107 ],
    "parents" : [ ],
    "children" : [ 10199027, 10116968 ]
  } ],
  "edges" : [ {
    "dbId" : 10199034,
    "stId" : "R-RNO-8853792",
    "displayName" : "RET tyrosine phosphorylation",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10199009 ],
    "following" : [ 10198989, 10198993, 10199492, 10199402, 10199038, 10199420, 10199453, 10199322, 10198977 ],
    "inputs" : [ 113592, 10199007 ],
    "outputs" : [ 29370, 10182431 ],
    "catalysts" : [ 10199007 ],
    "efs" : [ ],
    "diagramIds" : [ 34064 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199322,
    "stId" : "R-RNO-8854899",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10199034 ],
    "inputs" : [ 10108599, 10182431 ],
    "outputs" : [ 10182437 ],
    "efs" : [ ],
    "diagramIds" : [ 34089 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10202009,
    "stId" : "R-RNO-8871227",
    "displayName" : "RET binds GFRA4",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10199042 ],
    "inputs" : [ 10182423, 10198979 ],
    "outputs" : [ 10199001 ],
    "efs" : [ ],
    "diagramIds" : [ 34119 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199320,
    "stId" : "R-RNO-8854897",
    "displayName" : "p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10199038 ],
    "following" : [ 10199029 ],
    "inputs" : [ 10199015, 10199017 ],
    "outputs" : [ 10199019 ],
    "efs" : [ ],
    "diagramIds" : [ 34095 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199038,
    "stId" : "R-RNO-8853793",
    "displayName" : "p-5Y-RET complexes bind GRB2",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10199330, 10199034 ],
    "following" : [ 10199320 ],
    "inputs" : [ 10108594, 10199036 ],
    "outputs" : [ 10199015 ],
    "efs" : [ ],
    "diagramIds" : [ 34091 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199326,
    "stId" : "R-RNO-8854905",
    "displayName" : "p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10199029 ],
    "inputs" : [ 10199027, 10143211 ],
    "outputs" : [ 10199324 ],
    "efs" : [ ],
    "diagramIds" : [ 34102 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10198973,
    "stId" : "R-RNO-8853734",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10199330 ],
    "inputs" : [ 10108599, 10182433 ],
    "outputs" : [ 10182435 ],
    "efs" : [ ],
    "diagramIds" : [ 34086 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199453,
    "stId" : "R-RNO-8855747",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10199034 ],
    "inputs" : [ 10182431, 10199449 ],
    "outputs" : [ 10199451 ],
    "efs" : [ ],
    "diagramIds" : [ 34114 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199420,
    "stId" : "R-RNO-8855617",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10199034 ],
    "inputs" : [ 10182431, 10199416 ],
    "outputs" : [ 10199418 ],
    "efs" : [ ],
    "diagramIds" : [ 34078 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10198993,
    "stId" : "R-RNO-8853755",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10199034 ],
    "inputs" : [ 10182431, 10125512 ],
    "outputs" : [ 10198991 ],
    "efs" : [ ],
    "diagramIds" : [ 34111 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10202007,
    "stId" : "R-RNO-8871226",
    "displayName" : "RET binds GFRA1,GFRA2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10199031 ],
    "inputs" : [ 10182406, 10198979 ],
    "outputs" : [ 10198997 ],
    "efs" : [ ],
    "diagramIds" : [ 34117 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199031,
    "stId" : "R-RNO-8853789",
    "displayName" : "GDNF,NRTN bind RET:GFRA1,GFRA2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10202007 ],
    "following" : [ 10199009 ],
    "inputs" : [ 10198997, 10182400 ],
    "outputs" : [ 10198999 ],
    "efs" : [ ],
    "diagramIds" : [ 34046 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199029,
    "stId" : "R-RNO-8853774",
    "displayName" : "GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10199320 ],
    "following" : [ 10199326, 10199398 ],
    "inputs" : [ 113592, 10199019 ],
    "outputs" : [ 29370, 10199027 ],
    "efs" : [ ],
    "diagramIds" : [ 34098 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199402,
    "stId" : "R-RNO-8855564",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes bind FRS2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10199034 ],
    "inputs" : [ 10180750, 10182431 ],
    "outputs" : [ 10199400 ],
    "efs" : [ ],
    "diagramIds" : [ 34075 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10198989,
    "stId" : "R-RNO-8853753",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10199034 ],
    "inputs" : [ 10182431, 10198985 ],
    "outputs" : [ 10198987 ],
    "efs" : [ ],
    "diagramIds" : [ 34108 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199042,
    "stId" : "R-RNO-8853801",
    "displayName" : "PSPN binds RET:GFRA4",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10202009 ],
    "following" : [ 10199009 ],
    "inputs" : [ 10182419, 10199001 ],
    "outputs" : [ 10199003 ],
    "efs" : [ ],
    "diagramIds" : [ 34054 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199330,
    "stId" : "R-RNO-8854981",
    "displayName" : "SHC1 in the RET complex is phosphorylated",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10198977 ],
    "following" : [ 10199038, 10198973 ],
    "inputs" : [ 10198975 ],
    "outputs" : [ 10182433 ],
    "efs" : [ ],
    "diagramIds" : [ 34084 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199009,
    "stId" : "R-RNO-8853762",
    "displayName" : "RET dimerizes",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10199031, 10199040, 10199042 ],
    "following" : [ 10199328, 10199034 ],
    "inputs" : [ 10199005 ],
    "outputs" : [ 10199007 ],
    "efs" : [ ],
    "diagramIds" : [ 34061 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10198977,
    "stId" : "R-RNO-8853737",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes bind SHC1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10199034 ],
    "following" : [ 10199330 ],
    "inputs" : [ 10108630, 10182431 ],
    "outputs" : [ 10198975 ],
    "efs" : [ ],
    "diagramIds" : [ 34081 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199040,
    "stId" : "R-RNO-8853800",
    "displayName" : "ARTN binds RET:GFRA1,GFRA3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10198983 ],
    "following" : [ 10199009 ],
    "inputs" : [ 10198981, 10182367 ],
    "outputs" : [ 10198995 ],
    "efs" : [ ],
    "diagramIds" : [ 34050 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199328,
    "stId" : "R-RNO-8854908",
    "displayName" : "PKA phosphorylates RET:GDNF:GFRA dimer",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10199009 ],
    "inputs" : [ 113592, 10199007 ],
    "outputs" : [ 29370, 10199007 ],
    "catalysts" : [ 10175370 ],
    "efs" : [ ],
    "diagramIds" : [ 34068 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10198983,
    "stId" : "R-RNO-8853745",
    "displayName" : "RET binds GFRA1,GFRA3",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10199040 ],
    "inputs" : [ 10198979, 10182379 ],
    "outputs" : [ 10198981 ],
    "efs" : [ ],
    "diagramIds" : [ 34058 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199398,
    "stId" : "R-RNO-8855508",
    "displayName" : "p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10199029 ],
    "inputs" : [ 10199027, 10116968 ],
    "outputs" : [ 10199396 ],
    "efs" : [ ],
    "diagramIds" : [ 34105 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10199492,
    "stId" : "R-RNO-8855915",
    "displayName" : "2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10199034 ],
    "inputs" : [ 10199488, 10182431 ],
    "outputs" : [ 10199490 ],
    "efs" : [ ],
    "diagramIds" : [ 34072 ],
    "entityFunctionalStatus" : [ ]
  } ]
}