{ "dbId" : 10221915, "stId" : "R-RNO-69242", "speciesName" : "Rattus norvegicus", "nodes" : [ { "dbId" : 10103450, "stId" : "R-RNO-68744", "displayName" : "Psmb2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P40307", "standardIdentifier" : "uniprot:P40307", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb2" ], "parents" : [ 10103466 ], "children" : [ ] }, { "dbId" : 10120858, "stId" : "R-RNO-187541", "displayName" : "CUL1:SKP1:SKP2 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64807 ], "parents" : [ 10120864 ], "children" : [ 10103345, 10103341, 10103337 ] }, { "dbId" : 10103448, "stId" : "R-RNO-68738", "displayName" : "Psmb1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P18421", "standardIdentifier" : "uniprot:P18421", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb1" ], "parents" : [ 10103466 ], "children" : [ ] }, { "dbId" : 10103454, "stId" : "R-RNO-68750", "displayName" : "Psmb4 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P34067", "standardIdentifier" : "uniprot:P34067", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb4" ], "parents" : [ 10103466 ], "children" : [ ] }, { "dbId" : 10120862, "stId" : "R-RNO-187533", "displayName" : "Cks1b [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "diagramIds" : [ 64808 ], "identifier" : "B2RZ99", "standardIdentifier" : "uniprot:B2RZ99", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Cks1b" ], "parents" : [ 10120864 ], "children" : [ ] }, { "dbId" : 10103452, "stId" : "R-RNO-68747", "displayName" : "Psmb3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P40112", "standardIdentifier" : "uniprot:P40112", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb3" ], "parents" : [ 10103466 ], "children" : [ ] }, { "dbId" : 10103442, "stId" : "R-RNO-68808", "displayName" : "Psmd8 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "F1LMQ3", "standardIdentifier" : "uniprot:F1LMQ3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd8" ], "parents" : [ 10103444 ], "children" : [ ] }, { "dbId" : 10120851, "stId" : "R-RNO-187849", "displayName" : "p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "parents" : [ 10120938, 10120853 ], "children" : [ 10120849, 10120846 ] }, { "dbId" : 10103440, "stId" : "R-RNO-9908012", "displayName" : "19S RP lid particle 2 [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103444 ], "children" : [ 10103430, 10103438 ] }, { "dbId" : 10120849, "stId" : "R-RNO-187857", "displayName" : "phospho-p-S130-CDKN1A [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A8I5ZZ18", "standardIdentifier" : "uniprot:A0A8I5ZZ18", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10120851 ], "children" : [ ] }, { "dbId" : 10103446, "stId" : "R-RNO-9908177", "displayName" : "19S regulatory particle [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103486 ], "children" : [ 10103444, 10103416 ] }, { "dbId" : 10103444, "stId" : "R-RNO-9908021", "displayName" : "19S RP lid [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103446 ], "children" : [ 10103440, 10103442 ] }, { "dbId" : 10120853, "stId" : "R-RNO-187522", "displayName" : "Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64804 ], "parents" : [ 10120868 ], "children" : [ 10120851, 10103518 ] }, { "dbId" : 10103434, "stId" : "R-RNO-68804", "displayName" : "Psmd6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "F7FGV7", "standardIdentifier" : "uniprot:F7FGV7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd6" ], "parents" : [ 10103438 ], "children" : [ ] }, { "dbId" : 10120843, "stId" : "R-RNO-187516", "displayName" : "Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64803 ], "parents" : [ ], "children" : [ 10103876, 10103518 ] }, { "dbId" : 10103432, "stId" : "R-RNO-68798", "displayName" : "PSMD3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A8I5ZNE7", "standardIdentifier" : "uniprot:A0A8I5ZNE7", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10103438 ], "children" : [ ] }, { "dbId" : 10103438, "stId" : "R-RNO-9908004", "displayName" : "19S RP lid particle 3 [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103440 ], "children" : [ 10103436, 10103432, 10103434 ] }, { "dbId" : 10120846, "stId" : "R-RNO-187525", "displayName" : "phospho-Cdkn1b [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "O08769", "standardIdentifier" : "uniprot:O08769", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Cdkn1b", "p27Kip1", "rCG_29991" ], "parents" : [ 10120851 ], "children" : [ ] }, { "dbId" : 10103436, "stId" : "R-RNO-8866674", "displayName" : "Ghost homologue of SEM1 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 48895, "parents" : [ 10103438 ], "children" : [ ] }, { "dbId" : 10103426, "stId" : "R-RNO-68794", "displayName" : "Psmd13 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "B0BN93", "standardIdentifier" : "uniprot:B0BN93", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd13" ], "parents" : [ 10103428 ], "children" : [ ] }, { "dbId" : 10103424, "stId" : "R-RNO-68806", "displayName" : "Psmd7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A8I5ZM79", "standardIdentifier" : "uniprot:A0A8I5ZM79", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd7" ], "parents" : [ 10103428 ], "children" : [ ] }, { "dbId" : 10103430, "stId" : "R-RNO-9907993", "displayName" : "19S RP Lid Module 1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103440 ], "children" : [ 10103428, 10103418 ] }, { "dbId" : 10120839, "stId" : "R-RNO-198622", "displayName" : "Cdkn1b [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "diagramIds" : [ 64852 ], "identifier" : "O08769", "standardIdentifier" : "uniprot:O08769", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Cdkn1b", "p27Kip1", "rCG_29991" ], "parents" : [ 10123351, 10197556 ], "children" : [ ] }, { "dbId" : 10103428, "stId" : "R-RNO-9907994", "displayName" : "PSMD7:PSMD12:PSMD13:PSMD14 [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103430 ], "children" : [ 10103424, 10103426, 10103420, 10103422 ] }, { "dbId" : 10103482, "stId" : "R-RNO-9907911", "displayName" : "20S CP outer ring [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103484 ], "children" : [ 10103476, 10103478, 10103472, 10103474, 10103468, 10103470, 10103480 ] }, { "dbId" : 10166970, "stId" : "R-RNO-2466355", "displayName" : "Wapl [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "D4ADT3", "standardIdentifier" : "uniprot:D4ADT3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Wapl" ], "parents" : [ 10166980, 10166972 ], "children" : [ ] }, { "dbId" : 10103480, "stId" : "R-RNO-68736", "displayName" : "Psma7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P48004", "standardIdentifier" : "uniprot:P48004", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma7" ], "parents" : [ 10103482 ], "children" : [ ] }, { "dbId" : 10102969, "stId" : "R-RNO-174338", "displayName" : "PSMC1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P62193", "standardIdentifier" : "uniprot:P62193", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10102975 ], "children" : [ ] }, { "dbId" : 10166968, "stId" : "R-RNO-2468044", "displayName" : "PDS5 [nucleoplasm]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "parents" : [ 10166980, 10166972 ], "children" : [ 10166964, 10166966 ] }, { "dbId" : 10103486, "stId" : "R-RNO-68819", "displayName" : "26S proteasome [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64847 ], "parents" : [ ], "children" : [ 10103446, 10103484 ] }, { "dbId" : 10102975, "stId" : "R-RNO-9918359", "displayName" : "PSMC2:PSMC1 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10102977 ], "children" : [ 10102973, 10102969 ] }, { "dbId" : 10166974, "stId" : "R-RNO-2545179", "displayName" : "Cohesin:PDS5:WAPAL:Chromosomal Arm [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64869 ], "parents" : [ ], "children" : [ 1638790, 10166972 ] }, { "dbId" : 10103484, "stId" : "R-RNO-9907918", "displayName" : "20S core particle [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103486 ], "children" : [ 10103482, 10103466 ] }, { "dbId" : 10102973, "stId" : "R-RNO-174332", "displayName" : "PSMC2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q63347", "standardIdentifier" : "uniprot:Q63347", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10102975 ], "children" : [ ] }, { "dbId" : 10166972, "stId" : "R-RNO-2468042", "displayName" : "Cohesin:PDS5:WAPAL [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10167118, 10166974 ], "children" : [ 10166962, 10166968, 10166970 ] }, { "dbId" : 10103474, "stId" : "R-RNO-68730", "displayName" : "Psma4 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P21670", "standardIdentifier" : "uniprot:P21670", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma4" ], "parents" : [ 10103482 ], "children" : [ ] }, { "dbId" : 10102962, "stId" : "R-RNO-174311", "displayName" : "Psmd2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q4FZT9", "standardIdentifier" : "uniprot:Q4FZT9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd2" ], "parents" : [ 10102977 ], "children" : [ ] }, { "dbId" : 10166962, "stId" : "R-RNO-1641505", "displayName" : "Cohesin Complex [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10166972 ], "children" : [ 10166960, 10166956, 10166958, 10166952, 10166954 ] }, { "dbId" : 10103472, "stId" : "R-RNO-68728", "displayName" : "Psma3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P18422", "standardIdentifier" : "uniprot:P18422", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma3" ], "parents" : [ 10103482 ], "children" : [ ] }, { "dbId" : 10166960, "stId" : "R-RNO-163016", "displayName" : "Stag1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A8I6ADB5", "standardIdentifier" : "uniprot:A0A8I6ADB5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Stag1" ], "parents" : [ 10166978, 10166962 ], "children" : [ ] }, { "dbId" : 10103478, "stId" : "R-RNO-68734", "displayName" : "Psma6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P60901", "standardIdentifier" : "uniprot:P60901", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma6" ], "parents" : [ 10103482 ], "children" : [ ] }, { "dbId" : 10166966, "stId" : "R-RNO-2468051", "displayName" : "Pds5b [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q6TRW4", "standardIdentifier" : "uniprot:Q6TRW4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Pds5b" ], "parents" : [ 10166968 ], "children" : [ ] }, { "dbId" : 10103476, "stId" : "R-RNO-68732", "displayName" : "Psma5 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P34064", "standardIdentifier" : "uniprot:P34064", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma5" ], "parents" : [ 10103482 ], "children" : [ ] }, { "dbId" : 10112692, "stId" : "R-RNO-188389", "displayName" : "phospho-Rb1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P33568", "standardIdentifier" : "uniprot:P33568", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Rb1" ], "parents" : [ 10120965 ], "children" : [ ] }, { "dbId" : 10166964, "stId" : "R-RNO-2468043", "displayName" : "Pds5a [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A4L9P7", "standardIdentifier" : "uniprot:A4L9P7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Pds5a" ], "parents" : [ 10166968 ], "children" : [ ] }, { "dbId" : 10103466, "stId" : "R-RNO-9907905", "displayName" : "20S CP inner ring [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103484 ], "children" : [ 10103462, 10103456, 10103452, 10103454, 10103464, 10103448, 10103450 ] }, { "dbId" : 10102955, "stId" : "R-RNO-9918361", "displayName" : "Adrm1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q9JMB5", "standardIdentifier" : "uniprot:Q9JMB5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Adrm1" ], "parents" : [ 10103000 ], "children" : [ ] }, { "dbId" : 10166954, "stId" : "R-RNO-163009", "displayName" : "SMC3 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P97690", "standardIdentifier" : "uniprot:P97690", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10166962 ], "children" : [ ] }, { "dbId" : 10103464, "stId" : "R-RNO-68759", "displayName" : "Psmb7 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q9JHW0", "standardIdentifier" : "uniprot:Q9JHW0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb7" ], "parents" : [ 10103466 ], "children" : [ ] }, { "dbId" : 10120872, "stId" : "R-RNO-187568", "displayName" : "Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64814 ], "parents" : [ ], "children" : [ 10120868, 10102855 ] }, { "dbId" : 10166952, "stId" : "R-RNO-64561", "displayName" : "SMC1A [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q9Z1M9", "standardIdentifier" : "uniprot:Q9Z1M9", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10166978, 10166962 ], "children" : [ ] }, { "dbId" : 10103470, "stId" : "R-RNO-68726", "displayName" : "Psma2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P17220", "standardIdentifier" : "uniprot:P17220", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma2" ], "parents" : [ 10103482 ], "children" : [ ] }, { "dbId" : 10166958, "stId" : "R-RNO-163046", "displayName" : "Stag2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "D3ZXT2", "standardIdentifier" : "uniprot:D3ZXT2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Stag2" ], "parents" : [ 10166978, 10166962 ], "children" : [ ] }, { "dbId" : 10103468, "stId" : "R-RNO-68724", "displayName" : "Psma1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P18420", "standardIdentifier" : "uniprot:P18420", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma1" ], "parents" : [ 10103482 ], "children" : [ ] }, { "dbId" : 10166956, "stId" : "R-RNO-163042", "displayName" : "RAD21 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q4KLH7", "standardIdentifier" : "uniprot:Q4KLH7", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10166978, 10166962 ], "children" : [ ] }, { "dbId" : 10103458, "stId" : "R-RNO-68756", "displayName" : "Psmb6l1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A0G2JSL0", "standardIdentifier" : "uniprot:A0A0G2JSL0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb6l1" ], "parents" : [ 10103462 ], "children" : [ ] }, { "dbId" : 10103456, "stId" : "R-RNO-68753", "displayName" : "PSMB5 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P28075", "standardIdentifier" : "uniprot:P28075", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10103466 ], "children" : [ ] }, { "dbId" : 10120864, "stId" : "R-RNO-187547", "displayName" : "CUL1:SKP1:SKP2:CKS1B [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64809 ], "parents" : [ 10120868 ], "children" : [ 10120862, 10120858 ] }, { "dbId" : 10103462, "stId" : "R-RNO-68756-3", "displayName" : "Homologues of PSMB6 [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "parents" : [ 10103466 ], "children" : [ 10103460, 10103458 ] }, { "dbId" : 10102951, "stId" : "R-RNO-174348", "displayName" : "Psmd1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "O88761", "standardIdentifier" : "uniprot:O88761", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd1" ], "parents" : [ 10103000 ], "children" : [ ] }, { "dbId" : 10103460, "stId" : "R-RNO-68756-2", "displayName" : "Psmb6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P28073", "standardIdentifier" : "uniprot:P28073", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb6" ], "parents" : [ 10103462 ], "children" : [ ] }, { "dbId" : 10120868, "stId" : "R-RNO-187565", "displayName" : "Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64811 ], "parents" : [ 10120872 ], "children" : [ 10120853, 10120864 ] }, { "dbId" : 10103514, "stId" : "R-RNO-68373", "displayName" : "Cyclin E [nucleoplasm]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "parents" : [ 10103516 ], "children" : [ 10103508, 10103512 ] }, { "dbId" : 10167002, "stId" : "R-RNO-2468149", "displayName" : "Cdca5 [chromosome]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "B0BN32", "standardIdentifier" : "uniprot:B0BN32", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Cdca5" ], "parents" : [ 10167004 ], "children" : [ ] }, { "dbId" : 10103000, "stId" : "R-RNO-9918353", "displayName" : "19S RP base [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103046 ], "children" : [ 10102951, 10102998, 10102977, 10102985, 10102955 ] }, { "dbId" : 10103512, "stId" : "R-RNO-68367", "displayName" : "Ccne2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "D3ZQ41", "standardIdentifier" : "uniprot:D3ZQ41", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ccne2" ], "parents" : [ 10103514 ], "children" : [ ] }, { "dbId" : 10167000, "stId" : "R-RNO-2466357", "displayName" : "Cdca5 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "diagramIds" : [ 64857 ], "identifier" : "B0BN32", "standardIdentifier" : "uniprot:B0BN32", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Cdca5" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10103518, "stId" : "R-RNO-8848491", "displayName" : "CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "diagramIds" : [ 64816 ], "parents" : [ 10120843, 10120853 ], "children" : [ 10103516, 10103327 ] }, { "dbId" : 10167006, "stId" : "R-RNO-1638802", "displayName" : "Sister Chromosomal Arms:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64858 ], "parents" : [ ], "children" : [ 1638790, 10167004 ] }, { "dbId" : 10103004, "stId" : "R-RNO-174318", "displayName" : "Psmd8 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "F1LMQ3", "standardIdentifier" : "uniprot:F1LMQ3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd8" ], "parents" : [ 10103044 ], "children" : [ ] }, { "dbId" : 10103516, "stId" : "R-RNO-188362", "displayName" : "Cyclin E:p-T160-CDK2 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103518 ], "children" : [ 10103325, 10103514 ] }, { "dbId" : 10167004, "stId" : "R-RNO-2468165", "displayName" : "Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10167006 ], "children" : [ 10166836, 10166846, 10166842, 10167002 ] }, { "dbId" : 10120914, "stId" : "R-RNO-182512", "displayName" : "CDKN1A [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "diagramIds" : [ 64849 ], "identifier" : "A0A8I5ZZ18", "standardIdentifier" : "uniprot:A0A8I5ZZ18", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10123351 ], "children" : [ ] }, { "dbId" : 10102992, "stId" : "R-RNO-174315", "displayName" : "PSMC4 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q63570", "standardIdentifier" : "uniprot:Q63570", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10102998 ], "children" : [ ] }, { "dbId" : 10166993, "stId" : "R-RNO-2468046", "displayName" : "ESCO [nucleoplasm]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "diagramIds" : [ 64864 ], "parents" : [ ], "children" : [ 10166991, 10166986 ] }, { "dbId" : 10102998, "stId" : "R-RNO-9918349", "displayName" : "PSMC4:PSMC5 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103000 ], "children" : [ 10102996, 10102992 ] }, { "dbId" : 10102996, "stId" : "R-RNO-174312", "displayName" : "PSMC5 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P62198", "standardIdentifier" : "uniprot:P62198", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10102998 ], "children" : [ ] }, { "dbId" : 10103508, "stId" : "R-RNO-68363", "displayName" : "Ccne1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P39949", "standardIdentifier" : "uniprot:P39949", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ccne1" ], "parents" : [ 10103514 ], "children" : [ ] }, { "dbId" : 10166986, "stId" : "R-RNO-2466401", "displayName" : "Esco1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "B2GUX2", "standardIdentifier" : "uniprot:B2GUX2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Esco1" ], "parents" : [ 10166993 ], "children" : [ ] }, { "dbId" : 10102985, "stId" : "R-RNO-9918362", "displayName" : "PSMC3:PSMC6 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103000 ], "children" : [ 10102981, 10102983 ] }, { "dbId" : 10166991, "stId" : "R-RNO-2466400", "displayName" : "Esco2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A096MJS9", "standardIdentifier" : "uniprot:A0A096MJS9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Esco2" ], "parents" : [ 10166993 ], "children" : [ ] }, { "dbId" : 10166978, "stId" : "R-RNO-2468048", "displayName" : "Ac-Cohesin Complex [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10166980 ], "children" : [ 10166976, 10166960, 10166956, 10166958, 10166952 ] }, { "dbId" : 10102977, "stId" : "R-RNO-9918364", "displayName" : "PSMC2:PSMC1:PSMD2 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103000 ], "children" : [ 10102962, 10102975 ] }, { "dbId" : 10166976, "stId" : "R-RNO-2468050", "displayName" : "2xAcK-SMC3 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P97690", "standardIdentifier" : "uniprot:P97690", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10166978 ], "children" : [ ] }, { "dbId" : 10102983, "stId" : "R-RNO-174319", "displayName" : "Ghost homologue of PSMC6 [nucleoplasm]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 48895, "parents" : [ 10102985 ], "children" : [ ] }, { "dbId" : 10166982, "stId" : "R-RNO-2473153", "displayName" : "Ac-Cohesin:PDS5:WAPAL:Chromosomal Arm [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64855 ], "parents" : [ ], "children" : [ 1638790, 10166980 ] }, { "dbId" : 10102981, "stId" : "R-RNO-174313", "displayName" : "PSMC3 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q63569", "standardIdentifier" : "uniprot:Q63569", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10102985 ], "children" : [ ] }, { "dbId" : 10166980, "stId" : "R-RNO-2468047", "displayName" : "Ac-Cohesin:PDS5:WAPAL [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10167110, 10166982 ], "children" : [ 10166978, 10166968, 10166970 ] }, { "dbId" : 10103032, "stId" : "R-RNO-174328", "displayName" : "PSMD3 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A8I5ZNE7", "standardIdentifier" : "uniprot:A0A8I5ZNE7", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10103040 ], "children" : [ ] }, { "dbId" : 10103038, "stId" : "R-RNO-8866665", "displayName" : "Ghost homologue of SEM1 [nucleoplasm]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 48895, "parents" : [ 10103040 ], "children" : [ ] }, { "dbId" : 10103036, "stId" : "R-RNO-174316", "displayName" : "Psmd6 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "F7FGV7", "standardIdentifier" : "uniprot:F7FGV7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd6" ], "parents" : [ 10103040 ], "children" : [ ] }, { "dbId" : 10103026, "stId" : "R-RNO-9918357", "displayName" : "PSMD7:PSMD12:PSMD13:PSMD14 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103028 ], "children" : [ 10103012, 10103024, 10103020, 10103016 ] }, { "dbId" : 10103024, "stId" : "R-RNO-174309", "displayName" : "Psmd7 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A8I5ZM79", "standardIdentifier" : "uniprot:A0A8I5ZM79", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd7" ], "parents" : [ 10103026 ], "children" : [ ] }, { "dbId" : 10103028, "stId" : "R-RNO-9918360", "displayName" : "19S RP Lid Module 1 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103042 ], "children" : [ 10103008, 10103026 ] }, { "dbId" : 10120938, "stId" : "R-RNO-187912", "displayName" : "Cyclin A:Cdk2:phospho-p27/p21 complex [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64887 ], "parents" : [ ], "children" : [ 10120851, 10119020 ] }, { "dbId" : 10120936, "stId" : "R-RNO-187926", "displayName" : "Cyclin A:Cdk2:p21/p27 complex [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64800 ], "parents" : [ ], "children" : [ 10103876, 10119020 ] }, { "dbId" : 10103016, "stId" : "R-RNO-174326", "displayName" : "Psmd13 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "B0BN93", "standardIdentifier" : "uniprot:B0BN93", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd13" ], "parents" : [ 10103026 ], "children" : [ ] }, { "dbId" : 10103020, "stId" : "R-RNO-174329", "displayName" : "PSMD14 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q4V8E2", "standardIdentifier" : "uniprot:Q4V8E2", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10103026 ], "children" : [ ] }, { "dbId" : 10103008, "stId" : "R-RNO-174327", "displayName" : "Psmd11 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "F1LMZ8", "standardIdentifier" : "uniprot:F1LMZ8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd11" ], "parents" : [ 10103028 ], "children" : [ ] }, { "dbId" : 10167014, "stId" : "R-RNO-2574847", "displayName" : "Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10167112 ], "children" : [ 10167012, 10157383, 10157394, 10157373 ] }, { "dbId" : 10103012, "stId" : "R-RNO-174339", "displayName" : "Psmd12 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q5XIC6", "standardIdentifier" : "uniprot:Q5XIC6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd12" ], "parents" : [ 10103026 ], "children" : [ ] }, { "dbId" : 10167012, "stId" : "R-RNO-2468260", "displayName" : "Cdca5 [chromosome, centromeric region]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "B0BN32", "standardIdentifier" : "uniprot:B0BN32", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Cdca5" ], "parents" : [ 10167014 ], "children" : [ ] }, { "dbId" : 10103322, "stId" : "R-RNO-75202", "displayName" : "CCNA [nucleoplasm]", "schemaClass" : "CandidateSet", "speciesId" : 48895, "parents" : [ 10119018, 10119020, 10103327 ], "children" : [ 10103316, 10103320 ] }, { "dbId" : 10103320, "stId" : "R-RNO-68905", "displayName" : "Ccna2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A0G2JVY9", "standardIdentifier" : "uniprot:A0A0G2JVY9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ccna2" ], "parents" : [ 10103322 ], "children" : [ ] }, { "dbId" : 10103327, "stId" : "R-RNO-187952", "displayName" : "CCNA:p-T160-CDK2 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64830 ], "parents" : [ 10103518 ], "children" : [ 10103325, 10103322 ] }, { "dbId" : 10102812, "stId" : "R-RNO-939849", "displayName" : "Uba52 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P62986", "standardIdentifier" : "uniprot:P62986", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Uba52" ], "parents" : [ 10102855 ], "children" : [ ] }, { "dbId" : 10103325, "stId" : "R-RNO-187967", "displayName" : "phospho-p-T160-CDK2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q63699", "standardIdentifier" : "uniprot:Q63699", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10103516, 10103327 ], "children" : [ ] }, { "dbId" : 10103316, "stId" : "R-RNO-68891", "displayName" : "Ccna1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q6AY13", "standardIdentifier" : "uniprot:Q6AY13", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ccna1" ], "parents" : [ 10103322 ], "children" : [ ] }, { "dbId" : 10103818, "stId" : "R-RNO-182585", "displayName" : "CDKN1A [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "diagramIds" : [ 64850 ], "identifier" : "A0A8I5ZZ18", "standardIdentifier" : "uniprot:A0A8I5ZZ18", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10103876 ], "children" : [ ] }, { "dbId" : 10103820, "stId" : "R-RNO-182563", "displayName" : "Cdkn1b [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "diagramIds" : [ 64853 ], "identifier" : "O08769", "standardIdentifier" : "uniprot:O08769", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Cdkn1b", "p27Kip1", "rCG_29991" ], "parents" : [ 10103876 ], "children" : [ ] }, { "dbId" : 10109498, "stId" : "R-RNO-113843", "displayName" : "CDK4 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P35426", "standardIdentifier" : "uniprot:P35426", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10109500 ], "children" : [ ] }, { "dbId" : 10197562, "stId" : "R-RNO-8848438", "displayName" : "phospho-Cdkn1b [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "O08769", "standardIdentifier" : "uniprot:O08769", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Cdkn1b", "p27Kip1", "rCG_29991" ], "parents" : [ 10197564 ], "children" : [ ] }, { "dbId" : 10166842, "stId" : "R-RNO-2468151", "displayName" : "PDS5 [chromosome]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "parents" : [ 10167004 ], "children" : [ 10166838, 10166840 ] }, { "dbId" : 10109496, "stId" : "R-RNO-75811", "displayName" : "phospho-Ccnd1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "diagramIds" : [ 64842 ], "identifier" : "P39948", "standardIdentifier" : "uniprot:P39948", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ccnd1" ], "parents" : [ 10109500 ], "children" : [ ] }, { "dbId" : 10166840, "stId" : "R-RNO-2466361", "displayName" : "Pds5b [chromosome]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q6TRW4", "standardIdentifier" : "uniprot:Q6TRW4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Pds5b" ], "parents" : [ 10166842 ], "children" : [ ] }, { "dbId" : 10109502, "stId" : "R-RNO-75813", "displayName" : "phospho-Ccnd1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "diagramIds" : [ 64843 ], "identifier" : "P39948", "standardIdentifier" : "uniprot:P39948", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ccnd1" ], "parents" : [ 10109512, 10109506 ], "children" : [ ] }, { "dbId" : 10166846, "stId" : "R-RNO-2577090", "displayName" : "Wapl [chromosome]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "D4ADT3", "standardIdentifier" : "uniprot:D4ADT3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Wapl" ], "parents" : [ 10167004 ], "children" : [ ] }, { "dbId" : 10109500, "stId" : "R-RNO-75812", "displayName" : "phospho(T286)-Cyclin D1:Cdk4 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64839 ], "parents" : [ ], "children" : [ 10109496, 10109498 ] }, { "dbId" : 10197564, "stId" : "R-RNO-8848441", "displayName" : "p-Y88-CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64877 ], "parents" : [ ], "children" : [ 10197554, 10197562 ] }, { "dbId" : 10197554, "stId" : "R-RNO-8848425", "displayName" : "CCND1:CDK4,(CCNE1:CDK2) [cytosol]", "schemaClass" : "CandidateSet", "speciesId" : 48895, "parents" : [ 10197564, 10197556 ], "children" : [ 10197550, 10197552 ] }, { "dbId" : 10166834, "stId" : "R-RNO-2468146", "displayName" : "2xAcK-SMC3 [chromosome]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P97690", "standardIdentifier" : "uniprot:P97690", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10166836 ], "children" : [ ] }, { "dbId" : 10103345, "stId" : "R-RNO-975554", "displayName" : "SKP2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "B2GUZ0", "standardIdentifier" : "uniprot:B2GUZ0", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10120858 ], "children" : [ ] }, { "dbId" : 10197552, "stId" : "R-RNO-8848421", "displayName" : "Cyclin E1:CDK2 [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10197554 ], "children" : [ 10103693, 10103691 ] }, { "dbId" : 10166832, "stId" : "R-RNO-1638774", "displayName" : "SMC1A [chromosome]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q9Z1M9", "standardIdentifier" : "uniprot:Q9Z1M9", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10166836 ], "children" : [ ] }, { "dbId" : 10222647, "stId" : "R-RNO-68884", "displayName" : "Mitotic Telophase/Cytokinesis", "schemaClass" : "Pathway", "speciesId" : 48895, "diagramIds" : [ 64894 ] }, { "dbId" : 10197558, "stId" : "R-RNO-8848415", "displayName" : "p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64873 ], "parents" : [ ], "children" : [ 10197556, 10197381 ] }, { "dbId" : 10166838, "stId" : "R-RNO-2466360", "displayName" : "Pds5a [chromosome]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A4L9P7", "standardIdentifier" : "uniprot:A4L9P7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Pds5a" ], "parents" : [ 10166842 ], "children" : [ ] }, { "dbId" : 29358, "stId" : "R-ALL-29358", "displayName" : "ATP [nucleoplasm]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 64802, 64834, 64819, 64885, 64829 ], "identifier" : "30616", "standardIdentifier" : "chebi:30616", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10102837, "stId" : "R-RNO-939871", "displayName" : "Rps27a [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P62982", "standardIdentifier" : "uniprot:P62982", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Rps27a" ], "parents" : [ 10102855 ], "children" : [ ] }, { "dbId" : 10197556, "stId" : "R-RNO-8848419", "displayName" : "CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64871 ], "parents" : [ 10197558 ], "children" : [ 10120839, 10197554 ] }, { "dbId" : 10166836, "stId" : "R-RNO-1638788", "displayName" : "Ac-Cohesin Complex [chromosome]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10167004 ], "children" : [ 10166832, 10166834, 10166828, 10166830, 10166826 ] }, { "dbId" : 10166826, "stId" : "R-RNO-1638775", "displayName" : "RAD21 [chromosome]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q4KLH7", "standardIdentifier" : "uniprot:Q4KLH7", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10166836 ], "children" : [ ] }, { "dbId" : 10103337, "stId" : "R-RNO-187538", "displayName" : "Skp1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q6PEC4", "standardIdentifier" : "uniprot:Q6PEC4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Skp1" ], "parents" : [ 10120858 ], "children" : [ ] }, { "dbId" : 10197550, "stId" : "R-RNO-68331", "displayName" : "CDK4:CCND1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10197554 ], "children" : [ 10109504, 10197548 ] }, { "dbId" : 10166830, "stId" : "R-RNO-1638777", "displayName" : "Stag2 [chromosome]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "D3ZXT2", "standardIdentifier" : "uniprot:D3ZXT2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Stag2" ], "parents" : [ 10166836 ], "children" : [ ] }, { "dbId" : 10103341, "stId" : "R-RNO-187551", "displayName" : "Cul1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A8I5Y0H0", "standardIdentifier" : "uniprot:A0A8I5Y0H0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Cul1" ], "parents" : [ 10120858 ], "children" : [ ] }, { "dbId" : 10197548, "stId" : "R-RNO-68328", "displayName" : "Ccnd1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P39948", "standardIdentifier" : "uniprot:P39948", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ccnd1" ], "parents" : [ 10197550 ], "children" : [ ] }, { "dbId" : 10166828, "stId" : "R-RNO-1638773", "displayName" : "Stag1 [chromosome]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A8I6ADB5", "standardIdentifier" : "uniprot:A0A8I6ADB5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Stag1" ], "parents" : [ 10166836 ], "children" : [ ] }, { "dbId" : 10102816, "stId" : "R-RNO-939844", "displayName" : "Ubc [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q63429", "standardIdentifier" : "uniprot:Q63429", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ubc" ], "parents" : [ 10102855 ], "children" : [ ] }, { "dbId" : 29370, "stId" : "R-ALL-29370", "displayName" : "ADP [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 64882, 64876 ], "identifier" : "456216", "standardIdentifier" : "chebi:456216", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10102821, "stId" : "R-RNO-939847", "displayName" : "Ubb [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P0CG51", "standardIdentifier" : "uniprot:P0CG51", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ubb" ], "parents" : [ 10102855 ], "children" : [ ] }, { "dbId" : 10123354, "stId" : "R-RNO-198614", "displayName" : "phospho-p-T145-CDKN1A [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A8I5ZZ18", "standardIdentifier" : "uniprot:A0A8I5ZZ18", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10123359 ], "children" : [ ] }, { "dbId" : 10103390, "stId" : "R-RNO-68774", "displayName" : "PSMC3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q63569", "standardIdentifier" : "uniprot:Q63569", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10103394 ], "children" : [ ] }, { "dbId" : 10123359, "stId" : "R-RNO-198605", "displayName" : "p-T-CDKN1A/B [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "diagramIds" : [ 64881 ], "parents" : [ ], "children" : [ 10123357, 10123354 ] }, { "dbId" : 10103388, "stId" : "R-RNO-113595", "displayName" : "Ub [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "diagramIds" : [ 64846 ], "parents" : [ 10109512 ], "children" : [ 10103370, 10103362, 10103360, 10103364 ] }, { "dbId" : 10117724, "stId" : "R-RNO-157444", "displayName" : "Ccna2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A0G2JVY9", "standardIdentifier" : "uniprot:A0A0G2JVY9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ccna2" ], "parents" : [ 10118955 ], "children" : [ ] }, { "dbId" : 10123357, "stId" : "R-RNO-198629", "displayName" : "phospho-Cdkn1b [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "O08769", "standardIdentifier" : "uniprot:O08769", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Cdkn1b", "p27Kip1", "rCG_29991" ], "parents" : [ 10123359 ], "children" : [ ] }, { "dbId" : 198346, "stId" : "R-RNO-198346", "displayName" : "Phospho-Akt3 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q63484", "standardIdentifier" : "uniprot:Q63484", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Akt3" ], "parents" : [ 10123335 ], "children" : [ ] }, { "dbId" : 10123351, "stId" : "R-RNO-182504", "displayName" : "CDKN1A,CDKN1B [cytosol]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "diagramIds" : [ 64880 ], "parents" : [ ], "children" : [ 10120839, 10120914 ] }, { "dbId" : 10103370, "stId" : "R-RNO-939188", "displayName" : "Rps27a [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P62982", "standardIdentifier" : "uniprot:P62982", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Rps27a" ], "parents" : [ 10103388 ], "children" : [ ] }, { "dbId" : 10109512, "stId" : "R-RNO-177997", "displayName" : "multi-ubiquitinated phospho-(T286) Cyclin D1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64845 ], "parents" : [ ], "children" : [ 10103388, 10109502 ] }, { "dbId" : 10102863, "stId" : "R-RNO-174257", "displayName" : "phospho-Fzr1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "B1WCA1", "standardIdentifier" : "uniprot:B1WCA1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Fzr1" ], "parents" : [ 10120965 ], "children" : [ ] }, { "dbId" : 10222659, "stId" : "R-RNO-68877", "displayName" : "Mitotic Prometaphase", "schemaClass" : "Pathway", "speciesId" : 48895, "diagramIds" : [ 64893 ] }, { "dbId" : 10103362, "stId" : "R-RNO-939203", "displayName" : "Ubc [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q63429", "standardIdentifier" : "uniprot:Q63429", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ubc" ], "parents" : [ 10103388 ], "children" : [ ] }, { "dbId" : 10109506, "stId" : "R-RNO-75814", "displayName" : "phospho(T286)-Cyclin D1:Cdk4 [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64840 ], "parents" : [ ], "children" : [ 10109504, 10109502 ] }, { "dbId" : 10103360, "stId" : "R-RNO-939205", "displayName" : "Uba52 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P62986", "standardIdentifier" : "uniprot:P62986", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Uba52" ], "parents" : [ 10103388 ], "children" : [ ] }, { "dbId" : 10109504, "stId" : "R-RNO-68330", "displayName" : "CDK4 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P35426", "standardIdentifier" : "uniprot:P35426", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10109506, 10197550 ], "children" : [ ] }, { "dbId" : 10102855, "stId" : "R-RNO-68524", "displayName" : "Ub [nucleoplasm]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "diagramIds" : [ 64813 ], "parents" : [ 10120872 ], "children" : [ 10102812, 10102816, 10102821, 10102837 ] }, { "dbId" : 10123335, "stId" : "R-RNO-202074", "displayName" : "p-T,p-S-AKT [cytosol]", "schemaClass" : "CandidateSet", "speciesId" : 48895, "diagramIds" : [ 64883 ], "parents" : [ ], "children" : [ 10116556, 198377, 198346 ] }, { "dbId" : 10103364, "stId" : "R-RNO-939214", "displayName" : "Ubb [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P0CG51", "standardIdentifier" : "uniprot:P0CG51", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ubb" ], "parents" : [ 10103388 ], "children" : [ ] }, { "dbId" : 10103876, "stId" : "R-RNO-182558", "displayName" : "CDKN1A,CDKN1B [nucleoplasm]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "diagramIds" : [ 64799 ], "parents" : [ 10120936, 10120843 ], "children" : [ 10103820, 10103818 ] }, { "dbId" : 10103418, "stId" : "R-RNO-68790", "displayName" : "Psmd11 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "F1LMZ8", "standardIdentifier" : "uniprot:F1LMZ8", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd11" ], "parents" : [ 10103430 ], "children" : [ ] }, { "dbId" : 10103416, "stId" : "R-RNO-9908170", "displayName" : "19S RP base [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103446 ], "children" : [ 10103396, 10103414, 10103398, 10103394, 10103404 ] }, { "dbId" : 10103422, "stId" : "R-RNO-68722", "displayName" : "PSMD14 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q4V8E2", "standardIdentifier" : "uniprot:Q4V8E2", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10103428 ], "children" : [ ] }, { "dbId" : 10103420, "stId" : "R-RNO-68792", "displayName" : "Psmd12 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q5XIC6", "standardIdentifier" : "uniprot:Q5XIC6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd12" ], "parents" : [ 10103428 ], "children" : [ ] }, { "dbId" : 10103410, "stId" : "R-RNO-9907947", "displayName" : "PSMC2:PSMC1 [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103414 ], "children" : [ 10103408, 10103406 ] }, { "dbId" : 10117746, "stId" : "R-RNO-69734", "displayName" : "Cdc25b [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P48966", "standardIdentifier" : "uniprot:P48966", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Cdc25b" ], "parents" : [ 10119022 ], "children" : [ ] }, { "dbId" : 10103408, "stId" : "R-RNO-68771", "displayName" : "PSMC2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q63347", "standardIdentifier" : "uniprot:Q63347", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10103410 ], "children" : [ ] }, { "dbId" : 198377, "stId" : "R-RNO-198377", "displayName" : "Phospho-Akt2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P47197", "standardIdentifier" : "uniprot:P47197", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Akt2" ], "parents" : [ 10123335 ], "children" : [ ] }, { "dbId" : 10103414, "stId" : "R-RNO-9908171", "displayName" : "PSMC2:PSMC1:PSMD2 [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103416 ], "children" : [ 10103412, 10103410 ] }, { "dbId" : 10103412, "stId" : "R-RNO-68796", "displayName" : "Psmd2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q4FZT9", "standardIdentifier" : "uniprot:Q4FZT9", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd2" ], "parents" : [ 10103414 ], "children" : [ ] }, { "dbId" : 10103402, "stId" : "R-RNO-68780", "displayName" : "PSMC5 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P62198", "standardIdentifier" : "uniprot:P62198", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10103404 ], "children" : [ ] }, { "dbId" : 10103400, "stId" : "R-RNO-68777", "displayName" : "PSMC4 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q63570", "standardIdentifier" : "uniprot:Q63570", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10103404 ], "children" : [ ] }, { "dbId" : 10103406, "stId" : "R-RNO-68768", "displayName" : "PSMC1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P62193", "standardIdentifier" : "uniprot:P62193", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10103410 ], "children" : [ ] }, { "dbId" : 10103404, "stId" : "R-RNO-9907949", "displayName" : "PSMC4:PSMC5 [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103416 ], "children" : [ 10103400, 10103402 ] }, { "dbId" : 10103394, "stId" : "R-RNO-9907950", "displayName" : "PSMC3:PSMC6 [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103416 ], "children" : [ 10103392, 10103390 ] }, { "dbId" : 10103392, "stId" : "R-RNO-68783", "displayName" : "Ghost homologue of PSMC6 [cytosol]", "schemaClass" : "GenomeEncodedEntity", "speciesId" : 48895, "parents" : [ 10103394 ], "children" : [ ] }, { "dbId" : 10117728, "stId" : "R-RNO-157446", "displayName" : "Ccna1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q6AY13", "standardIdentifier" : "uniprot:Q6AY13", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ccna1" ], "parents" : [ 10118955 ], "children" : [ ] }, { "dbId" : 10103398, "stId" : "R-RNO-68786", "displayName" : "Psmd1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "O88761", "standardIdentifier" : "uniprot:O88761", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmd1" ], "parents" : [ 10103416 ], "children" : [ ] }, { "dbId" : 10103396, "stId" : "R-RNO-5665939", "displayName" : "Adrm1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q9JMB5", "standardIdentifier" : "uniprot:Q9JMB5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Adrm1" ], "parents" : [ 10103416 ], "children" : [ ] }, { "dbId" : 10103691, "stId" : "R-RNO-157440", "displayName" : "CDK2 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "diagramIds" : [ 64794 ], "identifier" : "Q63699", "standardIdentifier" : "uniprot:Q63699", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10118957, 10197552 ], "children" : [ ] }, { "dbId" : 10103693, "stId" : "R-RNO-157443", "displayName" : "Ccne1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P39949", "standardIdentifier" : "uniprot:P39949", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ccne1" ], "parents" : [ 10197552 ], "children" : [ ] }, { "dbId" : 10197381, "stId" : "R-RNO-8848007", "displayName" : "phospho-Ptk6 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "diagramIds" : [ 64872 ], "identifier" : "D3ZDS3", "standardIdentifier" : "uniprot:D3ZDS3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ptk6" ], "parents" : [ 10197558 ], "children" : [ ] }, { "dbId" : 10103729, "stId" : "R-RNO-143487", "displayName" : "Cdc25a [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "diagramIds" : [ 64892 ], "identifier" : "P48965", "standardIdentifier" : "uniprot:P48965", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Cdc25a" ], "parents" : [ 10119022 ], "children" : [ ] }, { "dbId" : 10103221, "stId" : "R-RNO-68365", "displayName" : "CDK2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q63699", "standardIdentifier" : "uniprot:Q63699", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10119020 ], "children" : [ ] }, { "dbId" : 2485002, "stId" : "R-ALL-2485002", "displayName" : "CoA-SH [nucleoplasm]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 64862 ], "identifier" : "57287", "standardIdentifier" : "chebi:57287", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10103722, "stId" : "R-RNO-1013870", "displayName" : "Cables1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "diagramIds" : [ 64823 ], "identifier" : "A0A8I6AIM6", "standardIdentifier" : "uniprot:A0A8I6AIM6", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Cables1" ], "parents" : [ ], "children" : [ ] }, { "dbId" : 10103717, "stId" : "R-RNO-69253", "displayName" : "WEE1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "diagramIds" : [ 64822 ], "identifier" : "Q63802", "standardIdentifier" : "uniprot:Q63802", "referenceType" : "ReferenceGeneProduct", "parents" : [ ], "children" : [ ] }, { "dbId" : 10103763, "stId" : "R-RNO-69226", "displayName" : "phospho-Rb1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P33568", "standardIdentifier" : "uniprot:P33568", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Rb1" ], "parents" : [ 10120963 ], "children" : [ ] }, { "dbId" : 10116556, "stId" : "R-RNO-198356", "displayName" : "phospho-p-T308,S473-AKT1 [cytosol]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P47196", "standardIdentifier" : "uniprot:P47196", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Akt1" ], "parents" : [ 10123335 ], "children" : [ ] }, { "dbId" : 113518, "stId" : "R-ALL-113518", "displayName" : "H2O [nucleoplasm]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 64825 ], "identifier" : "15377", "standardIdentifier" : "chebi:15377", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10103064, "stId" : "R-RNO-174341", "displayName" : "Psmb3 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P40112", "standardIdentifier" : "uniprot:P40112", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb3" ], "parents" : [ 10103091 ], "children" : [ ] }, { "dbId" : 10103068, "stId" : "R-RNO-174344", "displayName" : "PSMB5 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P28075", "standardIdentifier" : "uniprot:P28075", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10103091 ], "children" : [ ] }, { "dbId" : 10107677, "stId" : "R-RNO-69218", "displayName" : "CDK7 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P51952", "standardIdentifier" : "uniprot:P51952", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10107690 ], "children" : [ ] }, { "dbId" : 10103057, "stId" : "R-RNO-174335", "displayName" : "Psmb2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P40307", "standardIdentifier" : "uniprot:P40307", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb2" ], "parents" : [ 10103091 ], "children" : [ ] }, { "dbId" : 113550, "stId" : "R-ALL-113550", "displayName" : "Pi [nucleoplasm]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 64826 ], "identifier" : "43474", "standardIdentifier" : "chebi:43474", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10103050, "stId" : "R-RNO-174347", "displayName" : "Psmb1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P18421", "standardIdentifier" : "uniprot:P18421", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb1" ], "parents" : [ 10103091 ], "children" : [ ] }, { "dbId" : 1638792, "stId" : "R-ALL-1638792", "displayName" : "Sister Centromere [chromosome]", "schemaClass" : "OtherEntity", "speciesId" : 0, "diagramIds" : [ 64866 ], "parents" : [ 10167114, 10167112, 10167118, 10167110 ], "children" : [ ] }, { "dbId" : 10103042, "stId" : "R-RNO-9918356", "displayName" : "19S RP lid particle 2 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103044 ], "children" : [ 10103028, 10103040 ] }, { "dbId" : 10120963, "stId" : "R-RNO-187963", "displayName" : "FZR1,p-S795-RB1 [nucleoplasm]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "diagramIds" : [ 64835 ], "parents" : [ ], "children" : [ 10103763, 10118969 ] }, { "dbId" : 113560, "stId" : "R-ALL-113560", "displayName" : "Ac-CoA [nucleoplasm]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 64860 ], "identifier" : "57288", "standardIdentifier" : "chebi:57288", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10103040, "stId" : "R-RNO-9918363", "displayName" : "19S RP lid particle 3 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103042 ], "children" : [ 10103036, 10103038, 10103032 ] }, { "dbId" : 10103046, "stId" : "R-RNO-9918350", "displayName" : "19S regulatory particle [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103137 ], "children" : [ 10103044, 10103000 ] }, { "dbId" : 10103044, "stId" : "R-RNO-9918358", "displayName" : "19S RP lid [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103046 ], "children" : [ 10103042, 10103004 ] }, { "dbId" : 10120965, "stId" : "R-RNO-187920", "displayName" : "p-FZR1,p-RB1 [nucleoplasm]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "diagramIds" : [ 64836 ], "parents" : [ ], "children" : [ 10112692, 10102863 ] }, { "dbId" : 1638790, "stId" : "R-ALL-1638790", "displayName" : "Sister Chromatid [chromosome]", "schemaClass" : "OtherEntity", "speciesId" : 0, "diagramIds" : [ 64856 ], "parents" : [ 10167006, 10166974, 10166982 ], "children" : [ ] }, { "dbId" : 10157371, "stId" : "R-RNO-2468148", "displayName" : "2xAcK-SMC3 [chromosome, centromeric region]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P97690", "standardIdentifier" : "uniprot:P97690", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10157373 ], "children" : [ ] }, { "dbId" : 10118969, "stId" : "R-RNO-174099", "displayName" : "Fzr1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "B1WCA1", "standardIdentifier" : "uniprot:B1WCA1", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Fzr1" ], "parents" : [ 10120963 ], "children" : [ ] }, { "dbId" : 10103102, "stId" : "R-RNO-174345", "displayName" : "Psma2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P17220", "standardIdentifier" : "uniprot:P17220", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma2" ], "parents" : [ 10103133 ], "children" : [ ] }, { "dbId" : 10157373, "stId" : "R-RNO-2466014", "displayName" : "Ac-Cohesin Complex [chromosome, centromeric region]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10167014 ], "children" : [ 10157365, 10157361, 10157357, 10157353, 10157371 ] }, { "dbId" : 10103091, "stId" : "R-RNO-9918354", "displayName" : "20S CP inner ring [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103135 ], "children" : [ 10103089, 10103057, 10103085, 10103068, 10103081, 10103064, 10103050 ] }, { "dbId" : 10103089, "stId" : "R-RNO-174343", "displayName" : "Psmb4 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P34067", "standardIdentifier" : "uniprot:P34067", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb4" ], "parents" : [ 10103091 ], "children" : [ ] }, { "dbId" : 10157361, "stId" : "R-RNO-2466018", "displayName" : "Stag2 [chromosome, centromeric region]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "D3ZXT2", "standardIdentifier" : "uniprot:D3ZXT2", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Stag2" ], "parents" : [ 10157373 ], "children" : [ ] }, { "dbId" : 10103095, "stId" : "R-RNO-174333", "displayName" : "Psma1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P18420", "standardIdentifier" : "uniprot:P18420", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma1" ], "parents" : [ 10103133 ], "children" : [ ] }, { "dbId" : 113582, "stId" : "R-ALL-113582", "displayName" : "ADP [nucleoplasm]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 64820, 64837, 64805, 64886, 64831 ], "identifier" : "456216", "standardIdentifier" : "chebi:456216", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10157365, "stId" : "R-RNO-2466015", "displayName" : "SMC1A [chromosome, centromeric region]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q9Z1M9", "standardIdentifier" : "uniprot:Q9Z1M9", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10157373 ], "children" : [ ] }, { "dbId" : 10107690, "stId" : "R-RNO-69221", "displayName" : "CAK [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64832 ], "parents" : [ ], "children" : [ 10107684, 10107677, 10107688 ] }, { "dbId" : 10118955, "stId" : "R-RNO-170089", "displayName" : "CCNA [cytosol]", "schemaClass" : "CandidateSet", "speciesId" : 48895, "diagramIds" : [ 64793 ], "parents" : [ 10118957 ], "children" : [ 10117728, 10117724 ] }, { "dbId" : 10107688, "stId" : "R-RNO-59012", "displayName" : "Mnat1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "F7EX11", "standardIdentifier" : "uniprot:F7EX11", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Mnat1" ], "parents" : [ 10107690 ], "children" : [ ] }, { "dbId" : 10103081, "stId" : "R-RNO-174342-3", "displayName" : "Homologues of PSMB6 [nucleoplasm]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "parents" : [ 10103091 ], "children" : [ 10103079, 10103072 ] }, { "dbId" : 10157353, "stId" : "R-RNO-2466012", "displayName" : "RAD21 [chromosome, centromeric region]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q4KLH7", "standardIdentifier" : "uniprot:Q4KLH7", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10157373 ], "children" : [ ] }, { "dbId" : 10118957, "stId" : "R-RNO-187501", "displayName" : "CCNA:CDK2 [cytosol]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64795 ], "parents" : [ ], "children" : [ 10103691, 10118955 ] }, { "dbId" : 10103085, "stId" : "R-RNO-174331", "displayName" : "Psmb7 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q9JHW0", "standardIdentifier" : "uniprot:Q9JHW0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb7" ], "parents" : [ 10103091 ], "children" : [ ] }, { "dbId" : 10157357, "stId" : "R-RNO-2466017", "displayName" : "Stag1 [chromosome, centromeric region]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A8I6ADB5", "standardIdentifier" : "uniprot:A0A8I6ADB5", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Stag1" ], "parents" : [ 10157373 ], "children" : [ ] }, { "dbId" : 113592, "stId" : "R-ALL-113592", "displayName" : "ATP [cytosol]", "schemaClass" : "SimpleEntity", "speciesId" : 0, "diagramIds" : [ 64875, 64879 ], "identifier" : "30616", "standardIdentifier" : "chebi:30616", "referenceType" : "ReferenceMolecule", "parents" : [ ], "children" : [ ] }, { "dbId" : 10103072, "stId" : "R-RNO-174342", "displayName" : "Psmb6l1 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A0A0G2JSL0", "standardIdentifier" : "uniprot:A0A0G2JSL0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb6l1" ], "parents" : [ 10103081 ], "children" : [ ] }, { "dbId" : 10103079, "stId" : "R-RNO-174342-2", "displayName" : "Psmb6 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P28073", "standardIdentifier" : "uniprot:P28073", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psmb6" ], "parents" : [ 10103081 ], "children" : [ ] }, { "dbId" : 10107684, "stId" : "R-RNO-69220", "displayName" : "Ccnh [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q9R1A0", "standardIdentifier" : "uniprot:Q9R1A0", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Ccnh" ], "parents" : [ 10107690 ], "children" : [ ] }, { "dbId" : 10103131, "stId" : "R-RNO-174351", "displayName" : "Psma7 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P48004", "standardIdentifier" : "uniprot:P48004", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma7" ], "parents" : [ 10103133 ], "children" : [ ] }, { "dbId" : 10221913, "stId" : "R-RNO-69239", "displayName" : "Synthesis of DNA", "schemaClass" : "Pathway", "speciesId" : 48895, "diagramIds" : [ 64897 ] }, { "dbId" : 10103135, "stId" : "R-RNO-9918352", "displayName" : "20S core particle [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103137 ], "children" : [ 10103091, 10103133 ] }, { "dbId" : 10103133, "stId" : "R-RNO-9918351", "displayName" : "20S CP outer ring [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10103135 ], "children" : [ 10103109, 10103127, 10103095, 10103120, 10103116, 10103102, 10103131 ] }, { "dbId" : 10157394, "stId" : "R-RNO-2577088", "displayName" : "Wapl [chromosome, centromeric region]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "D4ADT3", "standardIdentifier" : "uniprot:D4ADT3", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Wapl" ], "parents" : [ 10167014 ], "children" : [ ] }, { "dbId" : 10103120, "stId" : "R-RNO-174340", "displayName" : "Psma5 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P34064", "standardIdentifier" : "uniprot:P34064", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma5" ], "parents" : [ 10103133 ], "children" : [ ] }, { "dbId" : 10103127, "stId" : "R-RNO-174314", "displayName" : "Psma6 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P60901", "standardIdentifier" : "uniprot:P60901", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma6" ], "parents" : [ 10103133 ], "children" : [ ] }, { "dbId" : 10167114, "stId" : "R-RNO-1638799", "displayName" : "Sister Centromeres:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64867 ], "parents" : [ ], "children" : [ 10167112, 1638792 ] }, { "dbId" : 10167112, "stId" : "R-RNO-2473148", "displayName" : "Centromere:Ac-Cohesin:PDS5:CDCA5:WAPAL [chromosome, centromeric region]", "schemaClass" : "Complex", "speciesId" : 48895, "parents" : [ 10167114 ], "children" : [ 10167014, 1638792 ] }, { "dbId" : 10167118, "stId" : "R-RNO-2545177", "displayName" : "Cohesin:PDS5:WAPAL:Centromere [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64861 ], "parents" : [ ], "children" : [ 10166972, 1638792 ] }, { "dbId" : 10103116, "stId" : "R-RNO-174324", "displayName" : "Psma4 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P21670", "standardIdentifier" : "uniprot:P21670", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma4" ], "parents" : [ 10103133 ], "children" : [ ] }, { "dbId" : 10157377, "stId" : "R-RNO-2468259", "displayName" : "Pds5a [chromosome, centromeric region]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "A4L9P7", "standardIdentifier" : "uniprot:A4L9P7", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Pds5a" ], "parents" : [ 10157383 ], "children" : [ ] }, { "dbId" : 10167110, "stId" : "R-RNO-2473149", "displayName" : "Ac-Cohesin:PDS5:WAPAL:Centromere [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64863 ], "parents" : [ ], "children" : [ 10166980, 1638792 ] }, { "dbId" : 10157383, "stId" : "R-RNO-2468261", "displayName" : "PDS5 [chromosome, centromeric region]", "schemaClass" : "DefinedSet", "speciesId" : 48895, "parents" : [ 10167014 ], "children" : [ 10157381, 10157377 ] }, { "dbId" : 10103109, "stId" : "R-RNO-174323", "displayName" : "Psma3 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "P18422", "standardIdentifier" : "uniprot:P18422", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Psma3" ], "parents" : [ 10103133 ], "children" : [ ] }, { "dbId" : 10157381, "stId" : "R-RNO-2468263", "displayName" : "Pds5b [chromosome, centromeric region]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q6TRW4", "standardIdentifier" : "uniprot:Q6TRW4", "referenceType" : "ReferenceGeneProduct", "geneNames" : [ "Pds5b" ], "parents" : [ 10157383 ], "children" : [ ] }, { "dbId" : 10119018, "stId" : "R-RNO-187907", "displayName" : "CCNA:p-Y15-CDK2 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64821 ], "parents" : [ ], "children" : [ 10119016, 10103322 ] }, { "dbId" : 10119016, "stId" : "R-RNO-187905", "displayName" : "phospho-p-Y15-CDK2 [nucleoplasm]", "schemaClass" : "EntityWithAccessionedSequence", "speciesId" : 48895, "identifier" : "Q63699", "standardIdentifier" : "uniprot:Q63699", "referenceType" : "ReferenceGeneProduct", "parents" : [ 10119018 ], "children" : [ ] }, { "dbId" : 10119022, "stId" : "R-RNO-187904", "displayName" : "Cdc25 A/B [nucleoplasm]", "schemaClass" : "CandidateSet", "speciesId" : 48895, "diagramIds" : [ 64827 ], "parents" : [ ], "children" : [ 10103729, 10117746 ] }, { "dbId" : 10119020, "stId" : "R-RNO-141608", "displayName" : "CCNA:CDK2 [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64797 ], "parents" : [ 10120938, 10120936 ], "children" : [ 10103221, 10103322 ] }, { "dbId" : 10103137, "stId" : "R-RNO-177750", "displayName" : "26S proteasome [nucleoplasm]", "schemaClass" : "Complex", "speciesId" : 48895, "diagramIds" : [ 64817 ], "parents" : [ ], "children" : [ 10103046, 10103135 ] } ], "edges" : [ { "dbId" : 10120856, "stId" : "R-RNO-187520", "displayName" : "Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10120943 ], "following" : [ 10120870 ], "inputs" : [ 29358, 10120843 ], "outputs" : [ 113582, 10120853 ], "catalysts" : [ 10120843 ], "efs" : [ ], "diagramIds" : [ 64801 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10167120, "stId" : "R-RNO-2473152", "displayName" : "Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10167116 ], "inputs" : [ 113560, 10167118 ], "outputs" : [ 2485002, 10167110 ], "catalysts" : [ 10166993 ], "efs" : [ ], "diagramIds" : [ 64859 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10120916, "stId" : "R-RNO-187828", "displayName" : "Translocation of p21 to the nucleus", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10120943 ], "inputs" : [ 10120914 ], "outputs" : [ 10103818 ], "efs" : [ ], "diagramIds" : [ 64848 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10166996, "stId" : "R-RNO-2468039", "displayName" : "Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10167008 ], "inputs" : [ 113560, 10166974 ], "outputs" : [ 2485002, 10166982 ], "catalysts" : [ 10166993 ], "efs" : [ ], "diagramIds" : [ 64868 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10109514, "stId" : "R-RNO-75825", "displayName" : "Proteasome mediated degradation of Cyclin D1", "schemaClass" : "BlackBoxEvent", "speciesId" : 0, "inputs" : [ 10109512 ], "outputs" : [ 10103388 ], "catalysts" : [ 10103486 ], "efs" : [ ], "diagramIds" : [ 64844 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10120841, "stId" : "R-RNO-187506", "displayName" : "Translocation of p27 to the nucleoplasm", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10120943 ], "inputs" : [ 10120839 ], "outputs" : [ 10103820 ], "efs" : [ ], "diagramIds" : [ 64851 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10120969, "stId" : "R-RNO-187949", "displayName" : "CAK-mediated phosphorylation of Cyclin A:Cdk2", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10119141, 10119025, 10120874 ], "following" : [ 10120967, 10120941 ], "inputs" : [ 29358, 10119020 ], "outputs" : [ 113582, 10103327 ], "catalysts" : [ 10107690 ], "efs" : [ ], "diagramIds" : [ 64828 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10167116, "stId" : "R-RNO-2473151", "displayName" : "CDCA5 (Sororin) enables cohesion of sister centromeres", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10167120 ], "inputs" : [ 10167110, 10167000, 1638792 ], "outputs" : [ 10167114 ], "efs" : [ ], "diagramIds" : [ 64865 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10109510, "stId" : "R-RNO-75823", "displayName" : "Relocalization of nuclearly localized Cyclin D1 to the cytoplasm", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10109496 ], "outputs" : [ 10109502 ], "efs" : [ ], "diagramIds" : [ 64841 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10120967, "stId" : "R-RNO-187948", "displayName" : "Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10120969 ], "inputs" : [ 29358, 10120963 ], "outputs" : [ 113582, 10120965 ], "catalysts" : [ 10103327 ], "efs" : [ ], "diagramIds" : [ 64833 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10109508, "stId" : "R-RNO-75822", "displayName" : "Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10109500 ], "outputs" : [ 10109506 ], "efs" : [ ], "diagramIds" : [ 64838 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10119109, "stId" : "R-RNO-174164", "displayName" : "Phosphorylation of Cyclin A:Cdk2 at Tyr 15", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10119141 ], "following" : [ 10119025 ], "inputs" : [ 29358, 10119020 ], "outputs" : [ 113582, 10119018 ], "catalysts" : [ 10103717 ], "efs" : [ ], "activators" : [ 10103722 ], "diagramIds" : [ 64818 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10197560, "stId" : "R-RNO-8848414", "displayName" : "Activated PTK6 binds CDKN1B", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10197567 ], "inputs" : [ 10197556, 10197381 ], "outputs" : [ 10197558 ], "efs" : [ ], "diagramIds" : [ 64870 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10197567, "stId" : "R-RNO-8848436", "displayName" : "PTK6 phosphorylates CDKN1B", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10197560 ], "inputs" : [ 10197558, 113592 ], "outputs" : [ 10197381, 29370, 10197564 ], "catalysts" : [ 10197558 ], "efs" : [ ], "diagramIds" : [ 64874 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10119025, "stId" : "R-RNO-174110", "displayName" : "Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10119109 ], "following" : [ 10120969 ], "inputs" : [ 113518, 10119018 ], "outputs" : [ 113550, 10119020 ], "catalysts" : [ 10119022 ], "efs" : [ ], "diagramIds" : [ 64824 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10120874, "stId" : "R-RNO-187574", "displayName" : "Degradation of ubiquitinated p27/p21 by the 26S proteasome", "schemaClass" : "BlackBoxEvent", "speciesId" : 0, "preceding" : [ 10120877 ], "following" : [ 10120969 ], "inputs" : [ 10120872 ], "outputs" : [ 10102855, 10120864, 10103518 ], "catalysts" : [ 10103137 ], "efs" : [ ], "diagramIds" : [ 64815 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10118959, "stId" : "R-RNO-174054", "displayName" : "Formation of Cyclin A:Cdk2 complexes", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10119141 ], "inputs" : [ 10103691, 10118955 ], "outputs" : [ 10118957 ], "efs" : [ ], "diagramIds" : [ 64792 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10120943, "stId" : "R-RNO-187934", "displayName" : "Inactivation of Cyclin A:Cdk2 complexes by p27/p21", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10119141, 10120916, 10120841 ], "following" : [ 10120941, 10120856 ], "inputs" : [ 10103876, 10119020 ], "outputs" : [ 10120936 ], "catalysts" : [ 10103876 ], "efs" : [ ], "diagramIds" : [ 64798 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10120877, "stId" : "R-RNO-187575", "displayName" : "Ubiquitination of phospho-p27/p21", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10120870 ], "following" : [ 10120874 ], "inputs" : [ 10120868, 10102855 ], "outputs" : [ 10120872 ], "catalysts" : [ 10120868 ], "efs" : [ ], "diagramIds" : [ 64812 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10120941, "stId" : "R-RNO-187916", "displayName" : "Cyclin A:Cdk2 mediated phosphorylation of p27/p21", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10120943, 10120969 ], "inputs" : [ 29358, 10120936 ], "outputs" : [ 113582, 10120938 ], "catalysts" : [ 10120936 ], "efs" : [ ], "diagramIds" : [ 64884 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10120866, "stId" : "R-RNO-187545", "displayName" : "Association of Cks1 with SCF(Skp2) complex", "schemaClass" : "Reaction", "speciesId" : 0, "following" : [ 10120870 ], "inputs" : [ 10120862, 10120858 ], "outputs" : [ 10120864 ], "efs" : [ ], "diagramIds" : [ 64806 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10123361, "stId" : "R-RNO-198613", "displayName" : "AKT phosphorylates p21Cip1 and p27Kip1", "schemaClass" : "Reaction", "speciesId" : 0, "inputs" : [ 10123351, 113592 ], "outputs" : [ 29370, 10123359 ], "catalysts" : [ 10123335 ], "efs" : [ ], "diagramIds" : [ 64878 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10167008, "stId" : "R-RNO-2468041", "displayName" : "CDCA5 (Sororin) enables cohesion of sister chromosomal arms", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10166996 ], "inputs" : [ 1638790, 10166982, 10167000 ], "outputs" : [ 10167006 ], "efs" : [ ], "diagramIds" : [ 64854 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10120870, "stId" : "R-RNO-187552", "displayName" : "Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10120866, 10120856 ], "following" : [ 10120877 ], "inputs" : [ 10120853, 10120864 ], "outputs" : [ 10120868 ], "efs" : [ ], "diagramIds" : [ 64810 ], "entityFunctionalStatus" : [ ] }, { "dbId" : 10119141, "stId" : "R-RNO-174273", "displayName" : "Translocation of Cyclin A:Cdk2 complexes to the nucleus", "schemaClass" : "Reaction", "speciesId" : 0, "preceding" : [ 10118959 ], "following" : [ 10120969, 10119109, 10120943 ], "inputs" : [ 10118957 ], "outputs" : [ 10119020 ], "efs" : [ ], "diagramIds" : [ 64796 ], "entityFunctionalStatus" : [ ] } ], "subpathways" : [ { "dbId" : 10223069, "stId" : "R-RNO-187577", "displayName" : "SCF(Skp2)-mediated degradation of p27/p21", "events" : [ 10120874, 10120856, 10197560, 10197567, 10120877, 10120866, 10120870 ] }, { "dbId" : 10222269, "stId" : "R-RNO-75815", "displayName" : "Ubiquitin-dependent degradation of Cyclin D", "events" : [ 10109514, 10109510, 10109508 ] }, { "dbId" : 10224449, "stId" : "R-RNO-2468052", "displayName" : "Establishment of Sister Chromatid Cohesion", "events" : [ 10167116, 10167120, 10167008, 10166996 ] }, { "dbId" : 10222947, "stId" : "R-RNO-69656", "displayName" : "Cyclin A:Cdk2-associated events at S phase entry", "events" : [ 10120841, 10120969, 10118959, 10120943, 10120874, 10120856, 10197560, 10197567, 10120877, 10120866, 10120870, 10120941, 10119025, 10123361, 10120967, 10120916, 10119141, 10119109 ] } ] }