{
  "dbId" : 10224861,
  "stableId" : "R-RNO-5694530",
  "displayName" : "Cargo concentration in the ER",
  "nodes" : [ {
    "id" : 19584,
    "reactomeId" : 10126439,
    "displayName" : "SEC24C,D",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1389,
      "y" : 128
    },
    "minX" : 1355,
    "maxX" : 1424,
    "minY" : 117,
    "maxY" : 167,
    "prop" : {
      "x" : 1355,
      "y" : 117,
      "width" : 69,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1355,
      "y" : 117
    },
    "connectors" : [ {
      "edgeId" : 19583,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1389,
          "y" : 145
        },
        "to" : {
          "x" : 1389,
          "y" : 167
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19585,
    "reactomeId" : 10126433,
    "displayName" : "GOSR2,STX5",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1437,
      "y" : 296
    },
    "minX" : 1388,
    "maxX" : 1486,
    "minY" : 167,
    "maxY" : 310,
    "prop" : {
      "x" : 1388,
      "y" : 283,
      "width" : 98,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1395,
      "y" : 286
    },
    "connectors" : [ {
      "edgeId" : 19583,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1431,
          "y" : 277
        },
        "to" : {
          "x" : 1389,
          "y" : 167
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19586,
    "reactomeId" : 10126443,
    "displayName" : "SEC23A:SEC24C,D:GOSR2,STX5",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1591,
      "y" : 256
    },
    "minX" : 1524,
    "maxX" : 1665,
    "minY" : 232,
    "maxY" : 275,
    "prop" : {
      "x" : 1524,
      "y" : 238,
      "width" : 135,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1529,
      "y" : 240
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1659,
          "y" : 238
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1659,
          "y" : 238
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19583,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19588,
    "reactomeId" : 10126491,
    "displayName" : "hexameric LMAN1:MCFD2",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 716,
      "y" : 592
    },
    "minX" : 664,
    "maxX" : 789,
    "minY" : 568,
    "maxY" : 610,
    "prop" : {
      "x" : 664,
      "y" : 574,
      "width" : 105,
      "height" : 36
    },
    "textPosition" : {
      "x" : 669,
      "y" : 575
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 769,
          "y" : 574
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 769,
          "y" : 574
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19587,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 772,
          "y" : 588
        },
        "to" : {
          "x" : 789,
          "y" : 587
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19589,
    "reactomeId" : 10126493,
    "displayName" : "F8",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 748,
      "y" : 527
    },
    "minX" : 689,
    "maxX" : 813,
    "minY" : 498,
    "maxY" : 587,
    "prop" : {
      "x" : 689,
      "y" : 504,
      "width" : 118,
      "height" : 46
    },
    "textPosition" : {
      "x" : 736,
      "y" : 516
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 807,
          "y" : 504
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 807,
          "y" : 504
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19587,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 763,
          "y" : 556
        },
        "to" : {
          "x" : 789,
          "y" : 587
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19590,
    "reactomeId" : 10126495,
    "displayName" : "LMAN1:MCFD2:glycosylated FV, FVIII precursor",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 895,
      "y" : 578
    },
    "minX" : 840,
    "maxX" : 956,
    "minY" : 540,
    "maxY" : 610,
    "prop" : {
      "x" : 840,
      "y" : 546,
      "width" : 110,
      "height" : 64
    },
    "textPosition" : {
      "x" : 839,
      "y" : 561
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 950,
          "y" : 546
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 950,
          "y" : 546
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19587,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19592,
    "reactomeId" : 10126505,
    "displayName" : "TFGA, AREG precursors",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1063,
      "y" : 575
    },
    "minX" : 1021,
    "maxX" : 1155,
    "minY" : 557,
    "maxY" : 594,
    "prop" : {
      "x" : 1021,
      "y" : 557,
      "width" : 84,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1021,
      "y" : 558
    },
    "connectors" : [ {
      "edgeId" : 19591,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1111,
          "y" : 569
        },
        "to" : {
          "x" : 1155,
          "y" : 564
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19593,
    "reactomeId" : 10126499,
    "displayName" : "Cnih1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1140,
      "y" : 613
    },
    "minX" : 1112,
    "maxX" : 1175,
    "minY" : 564,
    "maxY" : 627,
    "prop" : {
      "x" : 1112,
      "y" : 600,
      "width" : 57,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1119,
      "y" : 603
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1169,
          "y" : 600
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1169,
          "y" : 600
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19591,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1144,
          "y" : 597
        },
        "to" : {
          "x" : 1155,
          "y" : 564
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19594,
    "reactomeId" : 10126507,
    "displayName" : "CNIH1:TFGA,AREG precursors",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1281,
      "y" : 591
    },
    "minX" : 1219,
    "maxX" : 1349,
    "minY" : 567,
    "maxY" : 609,
    "prop" : {
      "x" : 1219,
      "y" : 573,
      "width" : 124,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1220,
      "y" : 574
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1343,
          "y" : 573
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1343,
          "y" : 573
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19591,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19596,
    "reactomeId" : 10126526,
    "displayName" : "GRIA1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1409,
      "y" : 573
    },
    "minX" : 1380,
    "maxX" : 1485,
    "minY" : 553,
    "maxY" : 588,
    "prop" : {
      "x" : 1380,
      "y" : 559,
      "width" : 59,
      "height" : 29
    },
    "textPosition" : {
      "x" : 1387,
      "y" : 563
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1439,
          "y" : 559
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1439,
          "y" : 559
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19595,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1442,
          "y" : 567
        },
        "to" : {
          "x" : 1485,
          "y" : 560
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19597,
    "reactomeId" : 10126520,
    "displayName" : "CNIH2,3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1459,
      "y" : 612
    },
    "minX" : 1425,
    "maxX" : 1494,
    "minY" : 560,
    "maxY" : 625,
    "prop" : {
      "x" : 1425,
      "y" : 599,
      "width" : 69,
      "height" : 26
    },
    "textPosition" : {
      "x" : 1431,
      "y" : 601
    },
    "connectors" : [ {
      "edgeId" : 19595,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1465,
          "y" : 593
        },
        "to" : {
          "x" : 1485,
          "y" : 560
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19598,
    "reactomeId" : 10126528,
    "displayName" : "CNIH2,3:GRIA1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1570,
      "y" : 601
    },
    "minX" : 1524,
    "maxX" : 1623,
    "minY" : 578,
    "maxY" : 618,
    "prop" : {
      "x" : 1524,
      "y" : 584,
      "width" : 93,
      "height" : 34
    },
    "textPosition" : {
      "x" : 1540,
      "y" : 583
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1617,
          "y" : 584
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1617,
          "y" : 584
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19595,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19600,
    "reactomeId" : 10126546,
    "displayName" : "TMED2:TMED10 tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1696,
      "y" : 598
    },
    "minX" : 1642,
    "maxX" : 1808,
    "minY" : 556,
    "maxY" : 616,
    "prop" : {
      "x" : 1642,
      "y" : 580,
      "width" : 109,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1642,
      "y" : 581
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1751,
          "y" : 580
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1751,
          "y" : 580
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19599,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1744,
          "y" : 577
        },
        "to" : {
          "x" : 1808,
          "y" : 556
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19601,
    "reactomeId" : 10126560,
    "displayName" : "GPI-CD59, GPI-FOLR1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1813,
      "y" : 618
    },
    "minX" : 1768,
    "maxX" : 1859,
    "minY" : 556,
    "maxY" : 638,
    "prop" : {
      "x" : 1768,
      "y" : 599,
      "width" : 91,
      "height" : 39
    },
    "textPosition" : {
      "x" : 1777,
      "y" : 601
    },
    "connectors" : [ {
      "edgeId" : 19599,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1811,
          "y" : 593
        },
        "to" : {
          "x" : 1808,
          "y" : 556
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19602,
    "reactomeId" : 10126562,
    "displayName" : "TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1958,
      "y" : 602
    },
    "minX" : 1893,
    "maxX" : 2029,
    "minY" : 571,
    "maxY" : 627,
    "prop" : {
      "x" : 1893,
      "y" : 577,
      "width" : 130,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1892,
      "y" : 578
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2023,
          "y" : 577
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2023,
          "y" : 577
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19599,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19604,
    "reactomeId" : 10126598,
    "displayName" : "glycosylated LMAN cargo",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 349,
      "y" : 529
    },
    "minX" : 296,
    "maxX" : 420,
    "minY" : 511,
    "maxY" : 579,
    "prop" : {
      "x" : 296,
      "y" : 511,
      "width" : 106,
      "height" : 37
    },
    "textPosition" : {
      "x" : 304,
      "y" : 512
    },
    "connectors" : [ {
      "edgeId" : 19603,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 375,
          "y" : 554
        },
        "to" : {
          "x" : 420,
          "y" : 579
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19605,
    "reactomeId" : 10126578,
    "displayName" : "LMAN family receptors",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 320,
      "y" : 597
    },
    "minX" : 263,
    "maxX" : 420,
    "minY" : 577,
    "maxY" : 617,
    "prop" : {
      "x" : 263,
      "y" : 577,
      "width" : 115,
      "height" : 40
    },
    "textPosition" : {
      "x" : 278,
      "y" : 579
    },
    "connectors" : [ {
      "edgeId" : 19603,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 384,
          "y" : 586
        },
        "to" : {
          "x" : 420,
          "y" : 579
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19606,
    "reactomeId" : 10126600,
    "displayName" : "LMAN receptor:glycosylated cargo",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 560,
      "y" : 580
    },
    "minX" : 498,
    "maxX" : 629,
    "minY" : 554,
    "maxY" : 601,
    "prop" : {
      "x" : 498,
      "y" : 560,
      "width" : 125,
      "height" : 41
    },
    "textPosition" : {
      "x" : 498,
      "y" : 566
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 623,
          "y" : 560
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 623,
          "y" : 560
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19603,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19608,
    "reactomeId" : 10126417,
    "displayName" : "SAR1B:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1830,
      "y" : 197
    },
    "minX" : 1791,
    "maxX" : 1995,
    "minY" : 180,
    "maxY" : 226,
    "prop" : {
      "x" : 1791,
      "y" : 186,
      "width" : 78,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1792,
      "y" : 187
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1869,
          "y" : 186
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1869,
          "y" : 186
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19607,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1872,
          "y" : 203
        },
        "to" : {
          "x" : 1995,
          "y" : 226
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19609,
    "reactomeId" : 10126602,
    "displayName" : "COPII cargo:receptors",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1825,
      "y" : 269
    },
    "minX" : 1766,
    "maxX" : 1995,
    "minY" : 226,
    "maxY" : 290,
    "prop" : {
      "x" : 1766,
      "y" : 248,
      "width" : 118,
      "height" : 42
    },
    "textPosition" : {
      "x" : 1783,
      "y" : 251
    },
    "connectors" : [ {
      "edgeId" : 19607,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1890,
          "y" : 254
        },
        "to" : {
          "x" : 1995,
          "y" : 226
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19610,
    "reactomeId" : 10126773,
    "displayName" : "SEC23:SEC24",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1907,
      "y" : 126
    },
    "minX" : 1861,
    "maxX" : 1995,
    "minY" : 109,
    "maxY" : 226,
    "prop" : {
      "x" : 1861,
      "y" : 115,
      "width" : 93,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1861,
      "y" : 116
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1954,
          "y" : 115
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1954,
          "y" : 115
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19607,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1916,
          "y" : 140
        },
        "to" : {
          "x" : 1995,
          "y" : 226
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19611,
    "reactomeId" : 10126604,
    "displayName" : "COPII cargo receptors:SAR1B:GTP:SEC23:SEC24",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2164,
      "y" : 218
    },
    "minX" : 2107,
    "maxX" : 2228,
    "minY" : 187,
    "maxY" : 243,
    "prop" : {
      "x" : 2107,
      "y" : 193,
      "width" : 115,
      "height" : 50
    },
    "textPosition" : {
      "x" : 2118,
      "y" : 180
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2222,
          "y" : 193
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2222,
          "y" : 193
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19607,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19616,
    "reactomeId" : 10223363,
    "displayName" : "COPII-mediated vesicle transport",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 2107,
      "y" : 372
    },
    "minX" : 2009,
    "maxX" : 2206,
    "minY" : 325,
    "maxY" : 420,
    "prop" : {
      "x" : 2009,
      "y" : 325,
      "width" : 197,
      "height" : 95
    },
    "textPosition" : {
      "x" : 2027,
      "y" : 351
    },
    "connectors" : [ ]
  }, {
    "id" : 19569,
    "reactomeId" : 10186821,
    "displayName" : "Mia2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 281,
      "y" : 231
    },
    "minX" : 250,
    "maxX" : 370,
    "minY" : 208,
    "maxY" : 249,
    "prop" : {
      "x" : 250,
      "y" : 214,
      "width" : 63,
      "height" : 35
    },
    "textPosition" : {
      "x" : 263,
      "y" : 221
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 313,
          "y" : 214
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 313,
          "y" : 214
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19568,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 316,
          "y" : 233
        },
        "to" : {
          "x" : 370,
          "y" : 237
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19570,
    "reactomeId" : 10126762,
    "displayName" : "Preb",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 376,
      "y" : 205
    },
    "minX" : 344,
    "maxX" : 972,
    "minY" : 117,
    "maxY" : 254,
    "prop" : {
      "x" : 344,
      "y" : 189,
      "width" : 64,
      "height" : 33
    },
    "textPosition" : {
      "x" : 357,
      "y" : 195
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 408,
          "y" : 189
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 408,
          "y" : 189
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19568,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 372,
          "y" : 225
        },
        "to" : {
          "x" : 370,
          "y" : 237
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19577,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 404,
          "y" : 186
        },
        "to" : {
          "x" : 528,
          "y" : 117
        }
      }, {
        "from" : {
          "x" : 528,
          "y" : 117
        },
        "to" : {
          "x" : 933,
          "y" : 117
        }
      }, {
        "from" : {
          "x" : 933,
          "y" : 117
        },
        "to" : {
          "x" : 972,
          "y" : 254
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 408,
          "y" : 179
        },
        "b" : {
          "x" : 404,
          "y" : 186
        },
        "c" : {
          "x" : 412,
          "y" : 186
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 412,
          "y" : 186
        }
      }
    } ]
  }, {
    "id" : 19571,
    "reactomeId" : 10186823,
    "displayName" : "MIA2:PREB",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 514,
      "y" : 223
    },
    "minX" : 467,
    "maxX" : 687,
    "minY" : 200,
    "maxY" : 247,
    "prop" : {
      "x" : 467,
      "y" : 206,
      "width" : 94,
      "height" : 34
    },
    "textPosition" : {
      "x" : 477,
      "y" : 219
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 561,
          "y" : 206
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 561,
          "y" : 206
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19568,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19572,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 564,
          "y" : 229
        },
        "to" : {
          "x" : 687,
          "y" : 247
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19573,
    "reactomeId" : 10126435,
    "displayName" : "Sec24c",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 670,
      "y" : 137
    },
    "minX" : 617,
    "maxX" : 730,
    "minY" : 120,
    "maxY" : 247,
    "prop" : {
      "x" : 617,
      "y" : 126,
      "width" : 107,
      "height" : 22
    },
    "textPosition" : {
      "x" : 643,
      "y" : 126
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 724,
          "y" : 126
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 724,
          "y" : 126
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19572,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 671,
          "y" : 151
        },
        "to" : {
          "x" : 687,
          "y" : 247
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19574,
    "reactomeId" : 10186811,
    "displayName" : "Procollagen type VII:MIA3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 534,
      "y" : 277
    },
    "minX" : 471,
    "maxX" : 687,
    "minY" : 247,
    "maxY" : 302,
    "prop" : {
      "x" : 471,
      "y" : 253,
      "width" : 127,
      "height" : 49
    },
    "textPosition" : {
      "x" : 476,
      "y" : 267
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 598,
          "y" : 253
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 598,
          "y" : 253
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19572,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 601,
          "y" : 264
        },
        "to" : {
          "x" : 687,
          "y" : 247
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19580,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19575,
    "reactomeId" : 10126441,
    "displayName" : "Sec23a",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 808,
      "y" : 161
    },
    "minX" : 687,
    "maxX" : 1389,
    "minY" : 144,
    "maxY" : 247,
    "prop" : {
      "x" : 755,
      "y" : 150,
      "width" : 107,
      "height" : 22
    },
    "textPosition" : {
      "x" : 781,
      "y" : 150
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 862,
          "y" : 150
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 862,
          "y" : 150
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19572,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 792,
          "y" : 175
        },
        "to" : {
          "x" : 687,
          "y" : 247
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19583,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 865,
          "y" : 161
        },
        "to" : {
          "x" : 1389,
          "y" : 167
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19576,
    "reactomeId" : 10186827,
    "displayName" : "procollagen VII:MIA3:MIA2:PREB:SEC23A:SEC24C",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 844,
      "y" : 248
    },
    "minX" : 790,
    "maxX" : 904,
    "minY" : 211,
    "maxY" : 279,
    "prop" : {
      "x" : 790,
      "y" : 217,
      "width" : 108,
      "height" : 62
    },
    "textPosition" : {
      "x" : 792,
      "y" : 216
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 898,
          "y" : 217
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 898,
          "y" : 217
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19572,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19577,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19578,
    "reactomeId" : 10126478,
    "displayName" : "procollagen VII:SEC24C:SEC23A",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1075,
      "y" : 229
    },
    "minX" : 972,
    "maxX" : 1131,
    "minY" : 196,
    "maxY" : 257,
    "prop" : {
      "x" : 1026,
      "y" : 202,
      "width" : 99,
      "height" : 55
    },
    "textPosition" : {
      "x" : 1032,
      "y" : 208
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1125,
          "y" : 202
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1125,
          "y" : 202
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19577,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1023,
          "y" : 241
        },
        "to" : {
          "x" : 972,
          "y" : 254
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1017,
          "y" : 247
        },
        "b" : {
          "x" : 1023,
          "y" : 241
        },
        "c" : {
          "x" : 1015,
          "y" : 239
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1015,
          "y" : 239
        }
      }
    } ]
  }, {
    "id" : 19579,
    "reactomeId" : 10186831,
    "displayName" : "MIA2:MIA3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1041,
      "y" : 296
    },
    "minX" : 972,
    "maxX" : 1093,
    "minY" : 254,
    "maxY" : 307,
    "prop" : {
      "x" : 996,
      "y" : 285,
      "width" : 91,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1006,
      "y" : 286
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1087,
          "y" : 285
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1087,
          "y" : 285
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19577,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1022,
          "y" : 282
        },
        "to" : {
          "x" : 972,
          "y" : 254
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1014,
          "y" : 282
        },
        "b" : {
          "x" : 1022,
          "y" : 282
        },
        "c" : {
          "x" : 1018,
          "y" : 275
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1018,
          "y" : 275
        }
      }
    } ]
  }, {
    "id" : 19581,
    "reactomeId" : 10186809,
    "displayName" : "Mia3",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 290,
      "y" : 277
    },
    "minX" : 253,
    "maxX" : 378,
    "minY" : 255,
    "maxY" : 293,
    "prop" : {
      "x" : 253,
      "y" : 261,
      "width" : 74,
      "height" : 32
    },
    "textPosition" : {
      "x" : 271,
      "y" : 266
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 327,
          "y" : 261
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 327,
          "y" : 261
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19580,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 330,
          "y" : 277
        },
        "to" : {
          "x" : 378,
          "y" : 278
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19582,
    "reactomeId" : 10126476,
    "displayName" : "Procollagen type VII",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 341,
      "y" : 348
    },
    "minX" : 283,
    "maxX" : 406,
    "minY" : 278,
    "maxY" : 366,
    "prop" : {
      "x" : 283,
      "y" : 331,
      "width" : 117,
      "height" : 35
    },
    "textPosition" : {
      "x" : 283,
      "y" : 331
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 400,
          "y" : 331
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 400,
          "y" : 331
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19580,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 350,
          "y" : 328
        },
        "to" : {
          "x" : 378,
          "y" : 278
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 19568,
    "reactomeId" : 10186825,
    "displayName" : "MIA2 binds PREB",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 433,
      "y" : 232
    },
    "minX" : 370,
    "maxX" : 464,
    "minY" : 226,
    "maxY" : 238,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 370,
        "y" : 237
      },
      "to" : {
        "x" : 433,
        "y" : 232
      }
    }, {
      "from" : {
        "x" : 433,
        "y" : 232
      },
      "to" : {
        "x" : 464,
        "y" : 228
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 458,
        "y" : 233
      },
      "b" : {
        "x" : 464,
        "y" : 228
      },
      "c" : {
        "x" : 457,
        "y" : 225
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 457,
        "y" : 225
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 433,
        "y" : 232
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 433,
        "y" : 232
      }
    },
    "inputs" : [ {
      "id" : 19569,
      "points" : [ {
        "x" : 316,
        "y" : 233
      } ]
    }, {
      "id" : 19570,
      "points" : [ {
        "x" : 372,
        "y" : 225
      } ]
    } ],
    "outputs" : [ {
      "id" : 19571
    } ]
  }, {
    "id" : 19603,
    "reactomeId" : 10186815,
    "displayName" : "LMAN family proteins bind glycosylated cargo",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 451,
      "y" : 582
    },
    "minX" : 420,
    "maxX" : 495,
    "minY" : 576,
    "maxY" : 588,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 420,
        "y" : 579
      },
      "to" : {
        "x" : 451,
        "y" : 582
      }
    }, {
      "from" : {
        "x" : 451,
        "y" : 582
      },
      "to" : {
        "x" : 495,
        "y" : 581
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 488,
        "y" : 585
      },
      "b" : {
        "x" : 495,
        "y" : 581
      },
      "c" : {
        "x" : 488,
        "y" : 577
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 488,
        "y" : 577
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 451,
        "y" : 582
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 451,
        "y" : 582
      }
    },
    "inputs" : [ {
      "id" : 19604,
      "points" : [ {
        "x" : 375,
        "y" : 554
      } ]
    }, {
      "id" : 19605,
      "points" : [ {
        "x" : 384,
        "y" : 586
      } ]
    } ],
    "outputs" : [ {
      "id" : 19606
    } ]
  }, {
    "id" : 19587,
    "reactomeId" : 10186817,
    "displayName" : "Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 808,
      "y" : 586
    },
    "minX" : 789,
    "maxX" : 837,
    "minY" : 580,
    "maxY" : 592,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 789,
        "y" : 587
      },
      "to" : {
        "x" : 808,
        "y" : 586
      }
    }, {
      "from" : {
        "x" : 808,
        "y" : 586
      },
      "to" : {
        "x" : 837,
        "y" : 583
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 831,
        "y" : 588
      },
      "b" : {
        "x" : 837,
        "y" : 583
      },
      "c" : {
        "x" : 830,
        "y" : 580
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 830,
        "y" : 580
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 808,
        "y" : 586
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 808,
        "y" : 586
      }
    },
    "inputs" : [ {
      "id" : 19588,
      "points" : [ {
        "x" : 772,
        "y" : 588
      } ]
    }, {
      "id" : 19589,
      "points" : [ {
        "x" : 763,
        "y" : 556
      } ]
    } ],
    "outputs" : [ {
      "id" : 19590
    } ]
  }, {
    "id" : 19572,
    "reactomeId" : 10186829,
    "displayName" : "MIA2 and MIA3 load procollagen VII into COPII vesicles",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 742,
      "y" : 249
    },
    "minX" : 687,
    "maxX" : 787,
    "minY" : 243,
    "maxY" : 255,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 687,
        "y" : 247
      },
      "to" : {
        "x" : 742,
        "y" : 249
      }
    }, {
      "from" : {
        "x" : 742,
        "y" : 249
      },
      "to" : {
        "x" : 787,
        "y" : 248
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 780,
        "y" : 252
      },
      "b" : {
        "x" : 787,
        "y" : 248
      },
      "c" : {
        "x" : 780,
        "y" : 244
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 780,
        "y" : 244
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 742,
        "y" : 249
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 742,
        "y" : 249
      }
    },
    "inputs" : [ {
      "id" : 19573,
      "points" : [ {
        "x" : 671,
        "y" : 151
      } ]
    }, {
      "id" : 19574,
      "points" : [ {
        "x" : 601,
        "y" : 264
      } ]
    }, {
      "id" : 19571,
      "points" : [ {
        "x" : 564,
        "y" : 229
      } ]
    }, {
      "id" : 19575,
      "points" : [ {
        "x" : 792,
        "y" : 175
      } ]
    } ],
    "outputs" : [ {
      "id" : 19576
    } ]
  }, {
    "id" : 19591,
    "reactomeId" : 10186858,
    "displayName" : "CNIH1 binds TFGA and AREG precursors",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1185,
      "y" : 560
    },
    "minX" : 1155,
    "maxX" : 1225,
    "minY" : 554,
    "maxY" : 570,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1155,
        "y" : 564
      },
      "to" : {
        "x" : 1185,
        "y" : 560
      }
    }, {
      "from" : {
        "x" : 1185,
        "y" : 560
      },
      "to" : {
        "x" : 1225,
        "y" : 570
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1217,
        "y" : 572
      },
      "b" : {
        "x" : 1225,
        "y" : 570
      },
      "c" : {
        "x" : 1219,
        "y" : 564
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1219,
        "y" : 564
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1185,
        "y" : 560
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1185,
        "y" : 560
      }
    },
    "inputs" : [ {
      "id" : 19592,
      "points" : [ {
        "x" : 1111,
        "y" : 569
      } ]
    }, {
      "id" : 19593,
      "points" : [ {
        "x" : 1144,
        "y" : 597
      } ]
    } ],
    "outputs" : [ {
      "id" : 19594
    } ]
  }, {
    "id" : 19607,
    "reactomeId" : 10187027,
    "displayName" : "Inner coat assembly and cargo binding",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2047,
      "y" : 225
    },
    "minX" : 1995,
    "maxX" : 2104,
    "minY" : 219,
    "maxY" : 231,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1995,
        "y" : 226
      },
      "to" : {
        "x" : 2047,
        "y" : 225
      }
    }, {
      "from" : {
        "x" : 2047,
        "y" : 225
      },
      "to" : {
        "x" : 2104,
        "y" : 221
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2097,
        "y" : 225
      },
      "b" : {
        "x" : 2104,
        "y" : 221
      },
      "c" : {
        "x" : 2097,
        "y" : 217
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2097,
        "y" : 217
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2047,
        "y" : 225
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2047,
        "y" : 225
      }
    },
    "inputs" : [ {
      "id" : 19608,
      "points" : [ {
        "x" : 1872,
        "y" : 203
      } ]
    }, {
      "id" : 19609,
      "points" : [ {
        "x" : 1890,
        "y" : 254
      } ]
    }, {
      "id" : 19610,
      "points" : [ {
        "x" : 1916,
        "y" : 140
      } ]
    } ],
    "outputs" : [ {
      "id" : 19611
    } ]
  }, {
    "id" : 19577,
    "reactomeId" : 10186833,
    "displayName" : "MIA2 and MIA3 dissociate from procollagen VII vesicle",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 934,
      "y" : 261
    },
    "minX" : 901,
    "maxX" : 972,
    "minY" : 254,
    "maxY" : 267,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 901,
        "y" : 255
      },
      "to" : {
        "x" : 934,
        "y" : 261
      }
    }, {
      "from" : {
        "x" : 934,
        "y" : 261
      },
      "to" : {
        "x" : 972,
        "y" : 254
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 934,
        "y" : 261
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 934,
        "y" : 261
      }
    },
    "inputs" : [ {
      "id" : 19576
    } ],
    "outputs" : [ {
      "id" : 19578,
      "points" : [ {
        "x" : 1023,
        "y" : 241
      } ]
    }, {
      "id" : 19570,
      "points" : [ {
        "x" : 404,
        "y" : 186
      }, {
        "x" : 528,
        "y" : 117
      }, {
        "x" : 933,
        "y" : 117
      } ]
    }, {
      "id" : 19579,
      "points" : [ {
        "x" : 1022,
        "y" : 282
      } ]
    } ]
  }, {
    "id" : 19595,
    "reactomeId" : 10186856,
    "displayName" : "CNIH2,3 bind GRIA1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1506,
      "y" : 558
    },
    "minX" : 1485,
    "maxX" : 1544,
    "minY" : 552,
    "maxY" : 581,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1485,
        "y" : 560
      },
      "to" : {
        "x" : 1506,
        "y" : 558
      }
    }, {
      "from" : {
        "x" : 1506,
        "y" : 558
      },
      "to" : {
        "x" : 1544,
        "y" : 581
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1536,
        "y" : 581
      },
      "b" : {
        "x" : 1544,
        "y" : 581
      },
      "c" : {
        "x" : 1540,
        "y" : 574
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1540,
        "y" : 574
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1506,
        "y" : 558
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1506,
        "y" : 558
      }
    },
    "inputs" : [ {
      "id" : 19596,
      "points" : [ {
        "x" : 1442,
        "y" : 567
      } ]
    }, {
      "id" : 19597,
      "points" : [ {
        "x" : 1465,
        "y" : 593
      } ]
    } ],
    "outputs" : [ {
      "id" : 19598
    } ]
  }, {
    "id" : 19580,
    "reactomeId" : 10186813,
    "displayName" : "MIA3 binds procollagen VII",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 426,
      "y" : 280
    },
    "minX" : 378,
    "maxX" : 468,
    "minY" : 274,
    "maxY" : 286,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 378,
        "y" : 278
      },
      "to" : {
        "x" : 426,
        "y" : 280
      }
    }, {
      "from" : {
        "x" : 426,
        "y" : 280
      },
      "to" : {
        "x" : 468,
        "y" : 278
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 461,
        "y" : 282
      },
      "b" : {
        "x" : 468,
        "y" : 278
      },
      "c" : {
        "x" : 461,
        "y" : 274
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 461,
        "y" : 274
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 426,
        "y" : 280
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 426,
        "y" : 280
      }
    },
    "inputs" : [ {
      "id" : 19581,
      "points" : [ {
        "x" : 330,
        "y" : 277
      } ]
    }, {
      "id" : 19582,
      "points" : [ {
        "x" : 350,
        "y" : 328
      } ]
    } ],
    "outputs" : [ {
      "id" : 19574
    } ]
  }, {
    "id" : 19599,
    "reactomeId" : 10186703,
    "displayName" : "TMED2:TMED10 tetramer binds GPI anchored proteins",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1854,
      "y" : 560
    },
    "minX" : 1808,
    "maxX" : 1896,
    "minY" : 554,
    "maxY" : 574,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1808,
        "y" : 556
      },
      "to" : {
        "x" : 1854,
        "y" : 560
      }
    }, {
      "from" : {
        "x" : 1854,
        "y" : 560
      },
      "to" : {
        "x" : 1896,
        "y" : 574
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1888,
        "y" : 576
      },
      "b" : {
        "x" : 1896,
        "y" : 574
      },
      "c" : {
        "x" : 1891,
        "y" : 568
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1891,
        "y" : 568
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1854,
        "y" : 560
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1854,
        "y" : 560
      }
    },
    "inputs" : [ {
      "id" : 19600,
      "points" : [ {
        "x" : 1744,
        "y" : 577
      } ]
    }, {
      "id" : 19601,
      "points" : [ {
        "x" : 1811,
        "y" : 593
      } ]
    } ],
    "outputs" : [ {
      "id" : 19602
    } ]
  }, {
    "id" : 19583,
    "reactomeId" : 10186705,
    "displayName" : "SEC4C,D bind GOSR2 and STX5",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1463,
      "y" : 200
    },
    "minX" : 1389,
    "maxX" : 1548,
    "minY" : 167,
    "maxY" : 235,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1389,
        "y" : 167
      },
      "to" : {
        "x" : 1463,
        "y" : 200
      }
    }, {
      "from" : {
        "x" : 1463,
        "y" : 200
      },
      "to" : {
        "x" : 1548,
        "y" : 235
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1540,
        "y" : 236
      },
      "b" : {
        "x" : 1548,
        "y" : 235
      },
      "c" : {
        "x" : 1543,
        "y" : 229
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1543,
        "y" : 229
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1463,
        "y" : 200
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1463,
        "y" : 200
      }
    },
    "inputs" : [ {
      "id" : 19584,
      "points" : [ {
        "x" : 1389,
        "y" : 145
      } ]
    }, {
      "id" : 19585,
      "points" : [ {
        "x" : 1431,
        "y" : 277
      } ]
    }, {
      "id" : 19575,
      "points" : [ {
        "x" : 865,
        "y" : 161
      } ]
    } ],
    "outputs" : [ {
      "id" : 19586
    } ]
  } ],
  "compartments" : [ {
    "id" : 19612,
    "reactomeId" : 17957,
    "displayName" : "endoplasmic reticulum lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1214,
      "y" : 405
    },
    "minX" : 209,
    "maxX" : 2219,
    "minY" : 201,
    "maxY" : 610,
    "prop" : {
      "x" : 209,
      "y" : 201,
      "width" : 2010,
      "height" : 409
    },
    "textPosition" : {
      "x" : 997,
      "y" : 427
    },
    "insets" : {
      "x" : 219,
      "y" : 211,
      "width" : 1990,
      "height" : 389
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 19568, 19572, 19576, 19571, 19577, 19579, 19578, 19574, 19581, 19580, 19570, 19586, 19585, 19587, 19588, 19589, 19590, 19591, 19592, 19593, 19594, 19597, 19598, 19595, 19596, 19599, 19600, 19601, 19602, 19582, 19611, 19616, 19618, 19604, 19605, 19606, 19603, 19607, 19608, 19609, 19619, 19620, 19621, 19622, 19623, 19624, 19625, 19569 ]
  }, {
    "id" : 19613,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1145,
      "y" : 447
    },
    "minX" : 0,
    "maxX" : 2290,
    "minY" : 0,
    "maxY" : 894,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 2290,
      "height" : 894
    },
    "textPosition" : {
      "x" : 300,
      "y" : 148
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 2270,
      "height" : 874
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 19612, 19573, 19575, 19584, 19583, 19617, 19610 ]
  } ],
  "notes" : [ ],
  "links" : [ {
    "id" : 19617,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1038,
      "y" : 132
    },
    "minX" : 727,
    "maxX" : 1349,
    "minY" : 126,
    "maxY" : 138,
    "segments" : [ {
      "from" : {
        "x" : 727,
        "y" : 136
      },
      "to" : {
        "x" : 1349,
        "y" : 128
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1032,
        "y" : 126
      },
      "b" : {
        "x" : 1044,
        "y" : 138
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1038,
        "y" : 132
      }
    },
    "inputs" : [ {
      "id" : 19573
    } ],
    "outputs" : [ {
      "id" : 19584
    } ]
  }, {
    "id" : 19618,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 2139,
      "y" : 284
    },
    "minX" : 2124,
    "maxX" : 2154,
    "minY" : 246,
    "maxY" : 322,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 2154,
        "y" : 246
      },
      "to" : {
        "x" : 2124,
        "y" : 322
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2123,
        "y" : 314
      },
      "b" : {
        "x" : 2124,
        "y" : 322
      },
      "c" : {
        "x" : 2130,
        "y" : 317
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 2130,
        "y" : 317
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2133,
        "y" : 278
      },
      "b" : {
        "x" : 2145,
        "y" : 290
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2139,
        "y" : 284
      }
    },
    "inputs" : [ {
      "id" : 19611
    } ],
    "outputs" : [ {
      "id" : 19616
    } ]
  }, {
    "id" : 19619,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1550,
      "y" : 433
    },
    "minX" : 1311,
    "maxX" : 1789,
    "minY" : 296,
    "maxY" : 570,
    "segments" : [ {
      "from" : {
        "x" : 1311,
        "y" : 570
      },
      "to" : {
        "x" : 1789,
        "y" : 296
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1544,
        "y" : 427
      },
      "b" : {
        "x" : 1556,
        "y" : 439
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1550,
        "y" : 433
      }
    },
    "inputs" : [ {
      "id" : 19594
    } ],
    "outputs" : [ {
      "id" : 19609
    } ]
  }, {
    "id" : 19620,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1138,
      "y" : 379
    },
    "minX" : 1086,
    "maxX" : 1760,
    "minY" : 260,
    "maxY" : 385,
    "segments" : [ {
      "from" : {
        "x" : 1086,
        "y" : 260
      },
      "to" : {
        "x" : 1138,
        "y" : 379
      }
    }, {
      "from" : {
        "x" : 1138,
        "y" : 379
      },
      "to" : {
        "x" : 1760,
        "y" : 278
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1132,
        "y" : 373
      },
      "b" : {
        "x" : 1144,
        "y" : 385
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1138,
        "y" : 379
      }
    },
    "inputs" : [ {
      "id" : 19578
    } ],
    "outputs" : [ {
      "id" : 19609
    } ]
  }, {
    "id" : 19621,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1695,
      "y" : 438
    },
    "minX" : 1583,
    "maxX" : 1808,
    "minY" : 296,
    "maxY" : 581,
    "segments" : [ {
      "from" : {
        "x" : 1583,
        "y" : 581
      },
      "to" : {
        "x" : 1808,
        "y" : 296
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1689,
        "y" : 432
      },
      "b" : {
        "x" : 1701,
        "y" : 444
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1695,
        "y" : 438
      }
    },
    "inputs" : [ {
      "id" : 19598
    } ],
    "outputs" : [ {
      "id" : 19609
    } ]
  }, {
    "id" : 19622,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1356,
      "y" : 423
    },
    "minX" : 953,
    "maxX" : 1760,
    "minY" : 288,
    "maxY" : 559,
    "segments" : [ {
      "from" : {
        "x" : 953,
        "y" : 559
      },
      "to" : {
        "x" : 1760,
        "y" : 288
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1350,
        "y" : 417
      },
      "b" : {
        "x" : 1362,
        "y" : 429
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1356,
        "y" : 423
      }
    },
    "inputs" : [ {
      "id" : 19590
    } ],
    "outputs" : [ {
      "id" : 19609
    } ]
  }, {
    "id" : 19623,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1711,
      "y" : 262
    },
    "minX" : 1662,
    "maxX" : 1760,
    "minY" : 256,
    "maxY" : 268,
    "segments" : [ {
      "from" : {
        "x" : 1662,
        "y" : 259
      },
      "to" : {
        "x" : 1760,
        "y" : 265
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1705,
        "y" : 256
      },
      "b" : {
        "x" : 1717,
        "y" : 268
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1711,
        "y" : 262
      }
    },
    "inputs" : [ {
      "id" : 19586
    } ],
    "outputs" : [ {
      "id" : 19609
    } ]
  }, {
    "id" : 19624,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1890,
      "y" : 435
    },
    "minX" : 1833,
    "maxX" : 1947,
    "minY" : 296,
    "maxY" : 574,
    "segments" : [ {
      "from" : {
        "x" : 1947,
        "y" : 574
      },
      "to" : {
        "x" : 1833,
        "y" : 296
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1884,
        "y" : 429
      },
      "b" : {
        "x" : 1896,
        "y" : 441
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1890,
        "y" : 435
      }
    },
    "inputs" : [ {
      "id" : 19602
    } ],
    "outputs" : [ {
      "id" : 19609
    } ]
  }, {
    "id" : 19625,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 714,
      "y" : 473
    },
    "minX" : 589,
    "maxX" : 1760,
    "minY" : 279,
    "maxY" : 557,
    "segments" : [ {
      "from" : {
        "x" : 589,
        "y" : 557
      },
      "to" : {
        "x" : 714,
        "y" : 473
      }
    }, {
      "from" : {
        "x" : 714,
        "y" : 473
      },
      "to" : {
        "x" : 1760,
        "y" : 279
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 708,
        "y" : 467
      },
      "b" : {
        "x" : 720,
        "y" : 479
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 714,
        "y" : 473
      }
    },
    "inputs" : [ {
      "id" : 19606
    } ],
    "outputs" : [ {
      "id" : 19609
    } ]
  } ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 2290,
  "minY" : 0,
  "maxY" : 894,
  "disease" : false
}