{
  "dbId" : 10223919,
  "stableId" : "R-RNO-450531",
  "displayName" : "Regulation of mRNA stability by proteins that bind AU-rich elements",
  "nodes" : [ {
    "id" : 67091,
    "reactomeId" : 10141782,
    "displayName" : "AUF1 Dimer (isoform p37 or p40)",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 209,
      "y" : 75
    },
    "minX" : 150,
    "maxX" : 257,
    "minY" : 51,
    "maxY" : 136,
    "prop" : {
      "x" : 162,
      "y" : 51,
      "width" : 95,
      "height" : 48
    },
    "textPosition" : {
      "x" : 164,
      "y" : 51
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 67090,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 185,
          "y" : 105
        },
        "to" : {
          "x" : 150,
          "y" : 136
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 161,
            "y" : 114
          },
          "b" : {
            "x" : 173,
            "y" : 126
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 167,
            "y" : 120
          }
        }
      }
    } ]
  }, {
    "id" : 67093,
    "reactomeId" : 10141786,
    "displayName" : "AUF1 Tetramer: Destabilized mRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 150,
      "y" : 211
    },
    "minX" : 96,
    "maxX" : 210,
    "minY" : 181,
    "maxY" : 279,
    "prop" : {
      "x" : 96,
      "y" : 187,
      "width" : 108,
      "height" : 48
    },
    "textPosition" : {
      "x" : 96,
      "y" : 186
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 204,
          "y" : 187
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 204,
          "y" : 187
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67090,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67094,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 139,
          "y" : 238
        },
        "to" : {
          "x" : 121,
          "y" : 279
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67092,
    "reactomeId" : 450444,
    "displayName" : "mRNA Transcript Targeted by AUF1(hnRNP D0)",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 87,
      "y" : 72
    },
    "minX" : 29,
    "maxX" : 150,
    "minY" : 44,
    "maxY" : 136,
    "prop" : {
      "x" : 29,
      "y" : 44,
      "width" : 116,
      "height" : 57
    },
    "textPosition" : {
      "x" : 29,
      "y" : 48
    },
    "connectors" : [ {
      "edgeId" : 67090,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 115,
          "y" : 104
        },
        "to" : {
          "x" : 150,
          "y" : 136
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67095,
    "reactomeId" : 10106576,
    "displayName" : "EIF4G1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 62,
      "y" : 247
    },
    "minX" : 33,
    "maxX" : 121,
    "minY" : 230,
    "maxY" : 279,
    "prop" : {
      "x" : 33,
      "y" : 236,
      "width" : 58,
      "height" : 22
    },
    "textPosition" : {
      "x" : 36,
      "y" : 236
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 91,
          "y" : 236
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 91,
          "y" : 236
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67094,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 82,
          "y" : 261
        },
        "to" : {
          "x" : 121,
          "y" : 279
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67097,
    "reactomeId" : 10114615,
    "displayName" : "Pabpc1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 62,
      "y" : 273
    },
    "minX" : 32,
    "maxX" : 121,
    "minY" : 256,
    "maxY" : 284,
    "prop" : {
      "x" : 32,
      "y" : 262,
      "width" : 60,
      "height" : 22
    },
    "textPosition" : {
      "x" : 34,
      "y" : 262
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 92,
          "y" : 262
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 92,
          "y" : 262
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67094,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 95,
          "y" : 276
        },
        "to" : {
          "x" : 121,
          "y" : 279
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67096,
    "reactomeId" : 10141855,
    "displayName" : "Homologues of HSPA1A",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 186,
      "y" : 251
    },
    "minX" : 121,
    "maxX" : 216,
    "minY" : 240,
    "maxY" : 279,
    "prop" : {
      "x" : 157,
      "y" : 240,
      "width" : 59,
      "height" : 22
    },
    "textPosition" : {
      "x" : 157,
      "y" : 227
    },
    "connectors" : [ {
      "edgeId" : 67094,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 160,
          "y" : 265
        },
        "to" : {
          "x" : 121,
          "y" : 279
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67099,
    "reactomeId" : 10137759,
    "displayName" : "HSPA8",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 197,
      "y" : 276
    },
    "minX" : 121,
    "maxX" : 235,
    "minY" : 259,
    "maxY" : 288,
    "prop" : {
      "x" : 165,
      "y" : 265,
      "width" : 64,
      "height" : 23
    },
    "textPosition" : {
      "x" : 172,
      "y" : 266
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 229,
          "y" : 265
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 229,
          "y" : 265
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67094,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 162,
          "y" : 277
        },
        "to" : {
          "x" : 121,
          "y" : 279
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67098,
    "reactomeId" : 10141845,
    "displayName" : "Hspb1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 64,
      "y" : 301
    },
    "minX" : 38,
    "maxX" : 121,
    "minY" : 279,
    "maxY" : 312,
    "prop" : {
      "x" : 38,
      "y" : 290,
      "width" : 52,
      "height" : 22
    },
    "textPosition" : {
      "x" : 40,
      "y" : 290
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 90,
          "y" : 290
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 90,
          "y" : 290
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67094,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 93,
          "y" : 290
        },
        "to" : {
          "x" : 121,
          "y" : 279
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67100,
    "reactomeId" : 10141857,
    "displayName" : "AUF1 Complexed with Translation and Heat Shock Proteins",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 149,
      "y" : 357
    },
    "minX" : 93,
    "maxX" : 212,
    "minY" : 319,
    "maxY" : 424,
    "prop" : {
      "x" : 93,
      "y" : 325,
      "width" : 113,
      "height" : 65
    },
    "textPosition" : {
      "x" : 92,
      "y" : 327
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 206,
          "y" : 325
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 206,
          "y" : 325
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67094,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67101,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 148,
          "y" : 393
        },
        "to" : {
          "x" : 148,
          "y" : 424
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67103,
    "reactomeId" : 10141801,
    "displayName" : "Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 150,
      "y" : 503
    },
    "minX" : 93,
    "maxX" : 213,
    "minY" : 465,
    "maxY" : 536,
    "prop" : {
      "x" : 93,
      "y" : 471,
      "width" : 114,
      "height" : 65
    },
    "textPosition" : {
      "x" : 95,
      "y" : 473
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 207,
          "y" : 471
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 207,
          "y" : 471
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67101,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67104,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67102,
    "reactomeId" : 10103388,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 64,
      "y" : 413
    },
    "minX" : 34,
    "maxX" : 148,
    "minY" : 403,
    "maxY" : 504,
    "prop" : {
      "x" : 34,
      "y" : 403,
      "width" : 61,
      "height" : 20
    },
    "textPosition" : {
      "x" : 52,
      "y" : 403
    },
    "connectors" : [ {
      "edgeId" : 67101,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 101,
          "y" : 416
        },
        "to" : {
          "x" : 148,
          "y" : 424
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 118,
            "y" : 414
          },
          "b" : {
            "x" : 130,
            "y" : 426
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 124,
            "y" : 420
          }
        }
      }
    }, {
      "edgeId" : 67104,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 12,
        "shape" : {
          "a" : {
            "x" : 56,
            "y" : 492
          },
          "b" : {
            "x" : 68,
            "y" : 504
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 62,
            "y" : 498
          }
        }
      }
    } ]
  }, {
    "id" : 67105,
    "reactomeId" : 10103486,
    "displayName" : "26S proteasome",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 240,
      "y" : 563
    },
    "minX" : 156,
    "maxX" : 293,
    "minY" : 539,
    "maxY" : 582,
    "prop" : {
      "x" : 194,
      "y" : 545,
      "width" : 93,
      "height" : 37
    },
    "textPosition" : {
      "x" : 198,
      "y" : 547
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 287,
          "y" : 545
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 287,
          "y" : 545
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67104,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 191,
          "y" : 564
        },
        "to" : {
          "x" : 164,
          "y" : 565
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 160,
          "y" : 565
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 160,
          "y" : 565
        }
      }
    } ]
  }, {
    "id" : 67107,
    "reactomeId" : 450523,
    "displayName" : "mRNA Transcript Targeted by BRF1",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 679,
      "y" : 530
    },
    "minX" : 619,
    "maxX" : 743,
    "minY" : 508,
    "maxY" : 580,
    "prop" : {
      "x" : 619,
      "y" : 508,
      "width" : 120,
      "height" : 44
    },
    "textPosition" : {
      "x" : 620,
      "y" : 512
    },
    "connectors" : [ {
      "edgeId" : 67106,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 707,
          "y" : 555
        },
        "to" : {
          "x" : 743,
          "y" : 580
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67109,
    "reactomeId" : 10141807,
    "displayName" : "BRF1:mRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 745,
      "y" : 648
    },
    "minX" : 703,
    "maxX" : 860,
    "minY" : 612,
    "maxY" : 711,
    "prop" : {
      "x" : 703,
      "y" : 631,
      "width" : 84,
      "height" : 34
    },
    "textPosition" : {
      "x" : 703,
      "y" : 630
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 787,
          "y" : 631
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 787,
          "y" : 631
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67106,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67110,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 744,
          "y" : 668
        },
        "to" : {
          "x" : 742,
          "y" : 711
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67116,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 790,
          "y" : 634
        },
        "to" : {
          "x" : 860,
          "y" : 612
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67121,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 781,
          "y" : 668
        },
        "to" : {
          "x" : 860,
          "y" : 702
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67108,
    "reactomeId" : 10141805,
    "displayName" : "Zfp36l1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 797,
      "y" : 536
    },
    "minX" : 743,
    "maxX" : 841,
    "minY" : 515,
    "maxY" : 580,
    "prop" : {
      "x" : 759,
      "y" : 521,
      "width" : 76,
      "height" : 30
    },
    "textPosition" : {
      "x" : 769,
      "y" : 525
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 835,
          "y" : 521
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 835,
          "y" : 521
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67106,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 778,
          "y" : 554
        },
        "to" : {
          "x" : 743,
          "y" : 580
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67111,
    "reactomeId" : 10139032,
    "displayName" : "Dcp1a",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 580,
      "y" : 733
    },
    "minX" : 409,
    "maxX" : 742,
    "minY" : 711,
    "maxY" : 747,
    "prop" : {
      "x" : 553,
      "y" : 719,
      "width" : 55,
      "height" : 28
    },
    "textPosition" : {
      "x" : 556,
      "y" : 722
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 608,
          "y" : 719
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 608,
          "y" : 719
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67110,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 611,
          "y" : 729
        },
        "to" : {
          "x" : 742,
          "y" : 711
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67134,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 550,
          "y" : 731
        },
        "to" : {
          "x" : 409,
          "y" : 721
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67113,
    "reactomeId" : 10139136,
    "displayName" : "Exosome Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 571,
      "y" : 664
    },
    "minX" : 409,
    "maxX" : 742,
    "minY" : 320,
    "maxY" : 721,
    "prop" : {
      "x" : 536,
      "y" : 647,
      "width" : 70,
      "height" : 35
    },
    "textPosition" : {
      "x" : 537,
      "y" : 647
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 606,
          "y" : 647
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 606,
          "y" : 647
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67146,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 569,
          "y" : 644
        },
        "to" : {
          "x" : 533,
          "y" : 320
        }
      }, {
        "from" : {
          "x" : 533,
          "y" : 320
        },
        "to" : {
          "x" : 446,
          "y" : 340
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67110,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 609,
          "y" : 673
        },
        "to" : {
          "x" : 742,
          "y" : 711
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67134,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 533,
          "y" : 676
        },
        "to" : {
          "x" : 409,
          "y" : 721
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67112,
    "reactomeId" : 10141766,
    "displayName" : "Xrn1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 580,
      "y" : 700
    },
    "minX" : 409,
    "maxX" : 742,
    "minY" : 684,
    "maxY" : 721,
    "prop" : {
      "x" : 556,
      "y" : 690,
      "width" : 49,
      "height" : 20
    },
    "textPosition" : {
      "x" : 562,
      "y" : 690
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 605,
          "y" : 690
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 605,
          "y" : 690
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67110,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 608,
          "y" : 701
        },
        "to" : {
          "x" : 742,
          "y" : 711
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67134,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 553,
          "y" : 703
        },
        "to" : {
          "x" : 409,
          "y" : 721
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67115,
    "reactomeId" : 10141817,
    "displayName" : "BRF1:mRNA Degradation Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 742,
      "y" : 790
    },
    "minX" : 696,
    "maxX" : 795,
    "minY" : 757,
    "maxY" : 817,
    "prop" : {
      "x" : 696,
      "y" : 763,
      "width" : 93,
      "height" : 54
    },
    "textPosition" : {
      "x" : 697,
      "y" : 768
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 789,
          "y" : 763
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 789,
          "y" : 763
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67110,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67114,
    "reactomeId" : 10139041,
    "displayName" : "Dcp2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 620,
      "y" : 591
    },
    "minX" : 409,
    "maxX" : 742,
    "minY" : 294,
    "maxY" : 721,
    "prop" : {
      "x" : 591,
      "y" : 579,
      "width" : 59,
      "height" : 25
    },
    "textPosition" : {
      "x" : 600,
      "y" : 581
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 650,
          "y" : 579
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 650,
          "y" : 579
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67146,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 616,
          "y" : 576
        },
        "to" : {
          "x" : 540,
          "y" : 294
        }
      }, {
        "from" : {
          "x" : 540,
          "y" : 294
        },
        "to" : {
          "x" : 446,
          "y" : 340
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67110,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 632,
          "y" : 607
        },
        "to" : {
          "x" : 742,
          "y" : 711
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67134,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 599,
          "y" : 607
        },
        "to" : {
          "x" : 409,
          "y" : 721
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67117,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 834,
      "y" : 655
    },
    "minX" : 814,
    "maxX" : 860,
    "minY" : 612,
    "maxY" : 702,
    "prop" : {
      "x" : 814,
      "y" : 644,
      "width" : 40,
      "height" : 23
    },
    "textPosition" : {
      "x" : 818,
      "y" : 645
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 849,
          "y" : 649
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 849,
          "y" : 649
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67116,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 840,
          "y" : 641
        },
        "to" : {
          "x" : 860,
          "y" : 612
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 844,
            "y" : 620
          },
          "b" : {
            "x" : 856,
            "y" : 632
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 850,
            "y" : 626
          }
        }
      }
    }, {
      "edgeId" : 67121,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 840,
          "y" : 670
        },
        "to" : {
          "x" : 860,
          "y" : 702
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 844,
            "y" : 680
          },
          "b" : {
            "x" : 856,
            "y" : 692
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 850,
            "y" : 686
          }
        }
      }
    } ]
  }, {
    "id" : 67119,
    "reactomeId" : 10141744,
    "displayName" : "Phosphorylated BRF1 (Ser92, Ser203):mRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1052,
      "y" : 611
    },
    "minX" : 920,
    "maxX" : 1191,
    "minY" : 573,
    "maxY" : 644,
    "prop" : {
      "x" : 996,
      "y" : 579,
      "width" : 113,
      "height" : 65
    },
    "textPosition" : {
      "x" : 997,
      "y" : 581
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1109,
          "y" : 579
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1109,
          "y" : 579
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67116,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 993,
          "y" : 611
        },
        "to" : {
          "x" : 920,
          "y" : 612
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 986,
          "y" : 615
        },
        "b" : {
          "x" : 993,
          "y" : 611
        },
        "c" : {
          "x" : 986,
          "y" : 607
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 986,
          "y" : 607
        }
      }
    }, {
      "edgeId" : 67124,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1112,
          "y" : 611
        },
        "to" : {
          "x" : 1191,
          "y" : 611
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67118,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 960,
      "y" : 655
    },
    "minX" : 920,
    "maxX" : 984,
    "minY" : 612,
    "maxY" : 702,
    "prop" : {
      "x" : 937,
      "y" : 642,
      "width" : 46,
      "height" : 26
    },
    "textPosition" : {
      "x" : 943,
      "y" : 644
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 978,
          "y" : 647
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 978,
          "y" : 647
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67116,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 947,
          "y" : 639
        },
        "to" : {
          "x" : 920,
          "y" : 612
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 927,
            "y" : 619
          },
          "b" : {
            "x" : 939,
            "y" : 631
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 933,
            "y" : 625
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 939,
          "y" : 637
        },
        "b" : {
          "x" : 947,
          "y" : 639
        },
        "c" : {
          "x" : 945,
          "y" : 631
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 945,
          "y" : 631
        }
      }
    }, {
      "edgeId" : 67121,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 952,
          "y" : 671
        },
        "to" : {
          "x" : 932,
          "y" : 702
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 936,
            "y" : 680
          },
          "b" : {
            "x" : 948,
            "y" : 692
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 942,
            "y" : 686
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 952,
          "y" : 679
        },
        "b" : {
          "x" : 952,
          "y" : 671
        },
        "c" : {
          "x" : 945,
          "y" : 675
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 945,
          "y" : 675
        }
      }
    } ]
  }, {
    "id" : 67120,
    "reactomeId" : 10116556,
    "displayName" : "phospho-p-T308,S473-AKT1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 918,
      "y" : 549
    },
    "minX" : 643,
    "maxX" : 991,
    "minY" : 242,
    "maxY" : 604,
    "prop" : {
      "x" : 851,
      "y" : 533,
      "width" : 134,
      "height" : 32
    },
    "textPosition" : {
      "x" : 861,
      "y" : 532
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 985,
          "y" : 533
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 985,
          "y" : 533
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67149,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 902,
          "y" : 530
        },
        "to" : {
          "x" : 648,
          "y" : 265
        }
      }, {
        "from" : {
          "x" : 648,
          "y" : 265
        },
        "to" : {
          "x" : 648,
          "y" : 250
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 647,
          "y" : 246
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 647,
          "y" : 246
        }
      }
    }, {
      "edgeId" : 67116,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 913,
          "y" : 568
        },
        "to" : {
          "x" : 904,
          "y" : 596
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 903,
          "y" : 600
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 903,
          "y" : 600
        }
      }
    } ]
  }, {
    "id" : 67123,
    "reactomeId" : 10120895,
    "displayName" : "phospho-p-S272,T222,T334-MAPKAPK2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 902,
      "y" : 773
    },
    "minX" : 848,
    "maxX" : 963,
    "minY" : 711,
    "maxY" : 837,
    "prop" : {
      "x" : 848,
      "y" : 746,
      "width" : 109,
      "height" : 55
    },
    "textPosition" : {
      "x" : 849,
      "y" : 749
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 957,
          "y" : 746
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 957,
          "y" : 746
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67136,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 901,
          "y" : 804
        },
        "to" : {
          "x" : 901,
          "y" : 829
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 901,
          "y" : 833
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 901,
          "y" : 833
        }
      }
    }, {
      "edgeId" : 67121,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 901,
          "y" : 743
        },
        "to" : {
          "x" : 900,
          "y" : 719
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 900,
          "y" : 715
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 900,
          "y" : 715
        }
      }
    } ]
  }, {
    "id" : 67122,
    "reactomeId" : 10141813,
    "displayName" : "Phosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1050,
      "y" : 703
    },
    "minX" : 932,
    "maxX" : 1193,
    "minY" : 666,
    "maxY" : 735,
    "prop" : {
      "x" : 989,
      "y" : 672,
      "width" : 123,
      "height" : 63
    },
    "textPosition" : {
      "x" : 995,
      "y" : 672
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1112,
          "y" : 672
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1112,
          "y" : 672
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67121,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 986,
          "y" : 702
        },
        "to" : {
          "x" : 932,
          "y" : 702
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 979,
          "y" : 706
        },
        "b" : {
          "x" : 986,
          "y" : 702
        },
        "c" : {
          "x" : 979,
          "y" : 698
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 979,
          "y" : 698
        }
      }
    }, {
      "edgeId" : 67127,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1115,
          "y" : 702
        },
        "to" : {
          "x" : 1193,
          "y" : 702
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67125,
    "reactomeId" : 10108845,
    "displayName" : "Ywhab",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1158,
      "y" : 776
    },
    "minX" : 1107,
    "maxX" : 1216,
    "minY" : 611,
    "maxY" : 848,
    "prop" : {
      "x" : 1107,
      "y" : 757,
      "width" : 103,
      "height" : 39
    },
    "textPosition" : {
      "x" : 1134,
      "y" : 766
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1210,
          "y" : 757
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1210,
          "y" : 757
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67140,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1170,
          "y" : 799
        },
        "to" : {
          "x" : 1203,
          "y" : 848
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67124,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1161,
          "y" : 754
        },
        "to" : {
          "x" : 1191,
          "y" : 611
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67127,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1167,
          "y" : 754
        },
        "to" : {
          "x" : 1193,
          "y" : 702
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67126,
    "reactomeId" : 10141746,
    "displayName" : "Phosphorylated BRF1 (Ser92, Ser203):mRNA:14-3-3 Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1339,
      "y" : 611
    },
    "minX" : 1262,
    "maxX" : 1423,
    "minY" : 580,
    "maxY" : 636,
    "prop" : {
      "x" : 1262,
      "y" : 586,
      "width" : 155,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1263,
      "y" : 587
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1417,
          "y" : 586
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1417,
          "y" : 586
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67124,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67128,
    "reactomeId" : 10143066,
    "displayName" : "Phosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA:14-3-3 Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1316,
      "y" : 700
    },
    "minX" : 1241,
    "maxX" : 1398,
    "minY" : 662,
    "maxY" : 732,
    "prop" : {
      "x" : 1241,
      "y" : 668,
      "width" : 151,
      "height" : 64
    },
    "textPosition" : {
      "x" : 1243,
      "y" : 669
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1392,
          "y" : 668
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1392,
          "y" : 668
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67127,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67131,
    "reactomeId" : 10141729,
    "displayName" : "Zfp36",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 474,
      "y" : 553
    },
    "minX" : 410,
    "maxX" : 530,
    "minY" : 537,
    "maxY" : 588,
    "prop" : {
      "x" : 424,
      "y" : 543,
      "width" : 100,
      "height" : 21
    },
    "textPosition" : {
      "x" : 451,
      "y" : 543
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 524,
          "y" : 543
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 524,
          "y" : 543
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67129,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 454,
          "y" : 567
        },
        "to" : {
          "x" : 410,
          "y" : 588
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67130,
    "reactomeId" : 450597,
    "displayName" : "mRNA Transcript Targeted by Tristetraproline",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 405,
      "y" : 494
    },
    "minX" : 344,
    "maxX" : 466,
    "minY" : 469,
    "maxY" : 588,
    "prop" : {
      "x" : 344,
      "y" : 469,
      "width" : 122,
      "height" : 51
    },
    "textPosition" : {
      "x" : 347,
      "y" : 470
    },
    "connectors" : [ {
      "edgeId" : 67129,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 406,
          "y" : 523
        },
        "to" : {
          "x" : 410,
          "y" : 588
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67133,
    "reactomeId" : 10141731,
    "displayName" : "TTP:mRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 409,
      "y" : 659
    },
    "minX" : 350,
    "maxX" : 865,
    "minY" : 632,
    "maxY" : 846,
    "prop" : {
      "x" : 371,
      "y" : 638,
      "width" : 76,
      "height" : 42
    },
    "textPosition" : {
      "x" : 372,
      "y" : 645
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 447,
          "y" : 638
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 447,
          "y" : 638
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67136,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 368,
          "y" : 657
        },
        "to" : {
          "x" : 352,
          "y" : 657
        }
      }, {
        "from" : {
          "x" : 352,
          "y" : 657
        },
        "to" : {
          "x" : 350,
          "y" : 843
        }
      }, {
        "from" : {
          "x" : 350,
          "y" : 843
        },
        "to" : {
          "x" : 865,
          "y" : 846
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67129,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67134,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 409,
          "y" : 683
        },
        "to" : {
          "x" : 409,
          "y" : 721
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67132,
    "reactomeId" : 10141715,
    "displayName" : "Tnpo1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 353,
      "y" : 556
    },
    "minX" : 323,
    "maxX" : 410,
    "minY" : 536,
    "maxY" : 588,
    "prop" : {
      "x" : 323,
      "y" : 542,
      "width" : 60,
      "height" : 29
    },
    "textPosition" : {
      "x" : 329,
      "y" : 546
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 383,
          "y" : 542
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 383,
          "y" : 542
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67129,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 378,
          "y" : 574
        },
        "to" : {
          "x" : 410,
          "y" : 588
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67135,
    "reactomeId" : 10141768,
    "displayName" : "TTP:mRNA Degradation Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 420,
      "y" : 807
    },
    "minX" : 370,
    "maxX" : 476,
    "minY" : 777,
    "maxY" : 832,
    "prop" : {
      "x" : 370,
      "y" : 783,
      "width" : 100,
      "height" : 49
    },
    "textPosition" : {
      "x" : 375,
      "y" : 783
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 470,
          "y" : 783
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 470,
          "y" : 783
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67134,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67137,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 834,
      "y" : 886
    },
    "minX" : 815,
    "maxX" : 865,
    "minY" : 846,
    "maxY" : 897,
    "prop" : {
      "x" : 815,
      "y" : 876,
      "width" : 38,
      "height" : 21
    },
    "textPosition" : {
      "x" : 818,
      "y" : 876
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 848,
          "y" : 881
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 848,
          "y" : 881
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67136,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 842,
          "y" : 873
        },
        "to" : {
          "x" : 865,
          "y" : 846
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 847,
            "y" : 853
          },
          "b" : {
            "x" : 859,
            "y" : 865
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 853,
            "y" : 859
          }
        }
      }
    } ]
  }, {
    "id" : 67139,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 977,
      "y" : 884
    },
    "minX" : 945,
    "maxX" : 998,
    "minY" : 846,
    "maxY" : 895,
    "prop" : {
      "x" : 957,
      "y" : 873,
      "width" : 40,
      "height" : 22
    },
    "textPosition" : {
      "x" : 960,
      "y" : 873
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 992,
          "y" : 878
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 992,
          "y" : 878
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67136,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 967,
          "y" : 870
        },
        "to" : {
          "x" : 945,
          "y" : 846
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 950,
            "y" : 852
          },
          "b" : {
            "x" : 962,
            "y" : 864
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 956,
            "y" : 858
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 959,
          "y" : 868
        },
        "b" : {
          "x" : 967,
          "y" : 870
        },
        "c" : {
          "x" : 965,
          "y" : 862
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 965,
          "y" : 862
        }
      }
    } ]
  }, {
    "id" : 67138,
    "reactomeId" : 10141723,
    "displayName" : "Phosphorylated TTP:mRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1054,
      "y" : 847
    },
    "minX" : 945,
    "maxX" : 1203,
    "minY" : 816,
    "maxY" : 873,
    "prop" : {
      "x" : 1004,
      "y" : 822,
      "width" : 100,
      "height" : 51
    },
    "textPosition" : {
      "x" : 1005,
      "y" : 824
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1104,
          "y" : 822
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1104,
          "y" : 822
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67136,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1001,
          "y" : 846
        },
        "to" : {
          "x" : 945,
          "y" : 846
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 994,
          "y" : 850
        },
        "b" : {
          "x" : 1001,
          "y" : 846
        },
        "c" : {
          "x" : 994,
          "y" : 842
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 994,
          "y" : 842
        }
      }
    }, {
      "edgeId" : 67140,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1107,
          "y" : 847
        },
        "to" : {
          "x" : 1203,
          "y" : 848
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67141,
    "reactomeId" : 10141725,
    "displayName" : "Phosphorylated TTP:mRNA:14-3-3 Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1333,
      "y" : 843
    },
    "minX" : 1255,
    "maxX" : 1418,
    "minY" : 819,
    "maxY" : 861,
    "prop" : {
      "x" : 1255,
      "y" : 825,
      "width" : 157,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1261,
      "y" : 826
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1412,
          "y" : 825
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1412,
          "y" : 825
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67140,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67143,
    "reactomeId" : 10141752,
    "displayName" : "Khsrp",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 490,
      "y" : 190
    },
    "minX" : 446,
    "maxX" : 593,
    "minY" : 175,
    "maxY" : 234,
    "prop" : {
      "x" : 467,
      "y" : 181,
      "width" : 46,
      "height" : 19
    },
    "textPosition" : {
      "x" : 468,
      "y" : 180
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 513,
          "y" : 181
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 513,
          "y" : 181
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67142,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 471,
          "y" : 203
        },
        "to" : {
          "x" : 446,
          "y" : 213
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67149,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 516,
          "y" : 199
        },
        "to" : {
          "x" : 593,
          "y" : 234
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67145,
    "reactomeId" : 10141754,
    "displayName" : "KSRP:mRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 447,
      "y" : 288
    },
    "minX" : 406,
    "maxX" : 495,
    "minY" : 263,
    "maxY" : 340,
    "prop" : {
      "x" : 406,
      "y" : 269,
      "width" : 83,
      "height" : 38
    },
    "textPosition" : {
      "x" : 406,
      "y" : 272
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 489,
          "y" : 269
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 489,
          "y" : 269
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67142,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67146,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 446,
          "y" : 310
        },
        "to" : {
          "x" : 446,
          "y" : 340
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67144,
    "reactomeId" : 450386,
    "displayName" : "mRNA Transcript Targeted by KSRP",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 360,
      "y" : 174
    },
    "minX" : 298,
    "maxX" : 446,
    "minY" : 152,
    "maxY" : 213,
    "prop" : {
      "x" : 298,
      "y" : 152,
      "width" : 125,
      "height" : 45
    },
    "textPosition" : {
      "x" : 301,
      "y" : 157
    },
    "connectors" : [ {
      "edgeId" : 67142,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 409,
          "y" : 200
        },
        "to" : {
          "x" : 446,
          "y" : 213
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67147,
    "reactomeId" : 10141758,
    "displayName" : "Parn",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 349,
      "y" : 298
    },
    "minX" : 320,
    "maxX" : 446,
    "minY" : 278,
    "maxY" : 340,
    "prop" : {
      "x" : 320,
      "y" : 284,
      "width" : 58,
      "height" : 28
    },
    "textPosition" : {
      "x" : 330,
      "y" : 287
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 378,
          "y" : 284
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 378,
          "y" : 284
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67146,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 381,
          "y" : 310
        },
        "to" : {
          "x" : 446,
          "y" : 340
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67148,
    "reactomeId" : 10141760,
    "displayName" : "KSRP:mRNA Degradation Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 447,
      "y" : 419
    },
    "minX" : 403,
    "maxX" : 497,
    "minY" : 388,
    "maxY" : 445,
    "prop" : {
      "x" : 403,
      "y" : 394,
      "width" : 88,
      "height" : 51
    },
    "textPosition" : {
      "x" : 402,
      "y" : 396
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 491,
          "y" : 394
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 491,
          "y" : 394
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67146,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67151,
    "reactomeId" : 10141827,
    "displayName" : "phospho-Khsrp",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 820,
      "y" : 228
    },
    "minX" : 687,
    "maxX" : 1037,
    "minY" : 86,
    "maxY" : 246,
    "prop" : {
      "x" : 769,
      "y" : 210,
      "width" : 102,
      "height" : 36
    },
    "textPosition" : {
      "x" : 769,
      "y" : 217
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 871,
          "y" : 210
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 871,
          "y" : 210
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67149,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 766,
          "y" : 230
        },
        "to" : {
          "x" : 687,
          "y" : 234
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 759,
          "y" : 234
        },
        "b" : {
          "x" : 766,
          "y" : 230
        },
        "c" : {
          "x" : 759,
          "y" : 226
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 759,
          "y" : 226
        }
      }
    }, {
      "edgeId" : 67153,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 847,
          "y" : 207
        },
        "to" : {
          "x" : 1037,
          "y" : 86
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67150,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 569,
      "y" : 185
    },
    "minX" : 545,
    "maxX" : 594,
    "minY" : 170,
    "maxY" : 234,
    "prop" : {
      "x" : 545,
      "y" : 171,
      "width" : 48,
      "height" : 29
    },
    "textPosition" : {
      "x" : 553,
      "y" : 175
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 588,
          "y" : 176
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 588,
          "y" : 176
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67149,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 576,
          "y" : 203
        },
        "to" : {
          "x" : 593,
          "y" : 234
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67152,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 722,
      "y" : 181
    },
    "minX" : 687,
    "maxX" : 744,
    "minY" : 165,
    "maxY" : 234,
    "prop" : {
      "x" : 701,
      "y" : 166,
      "width" : 42,
      "height" : 31
    },
    "textPosition" : {
      "x" : 705,
      "y" : 171
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 738,
          "y" : 171
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 738,
          "y" : 171
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67149,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 711,
          "y" : 200
        },
        "to" : {
          "x" : 687,
          "y" : 234
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 710,
          "y" : 208
        },
        "b" : {
          "x" : 711,
          "y" : 200
        },
        "c" : {
          "x" : 704,
          "y" : 203
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 704,
          "y" : 203
        }
      }
    } ]
  }, {
    "id" : 67155,
    "reactomeId" : 10141889,
    "displayName" : "Phosphorylated KSRP (Ser193):14-3-3zeta Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1153,
      "y" : 86
    },
    "minX" : 1099,
    "maxX" : 1213,
    "minY" : 45,
    "maxY" : 122,
    "prop" : {
      "x" : 1099,
      "y" : 51,
      "width" : 108,
      "height" : 71
    },
    "textPosition" : {
      "x" : 1098,
      "y" : 59
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1207,
          "y" : 51
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1207,
          "y" : 51
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67153,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67154,
    "reactomeId" : 10141885,
    "displayName" : "Ywhaz",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1026,
      "y" : 58
    },
    "minX" : 985,
    "maxX" : 1074,
    "minY" : 39,
    "maxY" : 86,
    "prop" : {
      "x" : 985,
      "y" : 45,
      "width" : 83,
      "height" : 26
    },
    "textPosition" : {
      "x" : 1004,
      "y" : 47
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1068,
          "y" : 45
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1068,
          "y" : 45
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67153,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1031,
          "y" : 74
        },
        "to" : {
          "x" : 1037,
          "y" : 86
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67157,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1099,
      "y" : 256
    },
    "minX" : 1075,
    "maxX" : 1125,
    "minY" : 217,
    "maxY" : 297,
    "prop" : {
      "x" : 1075,
      "y" : 244,
      "width" : 49,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1084,
      "y" : 245
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1119,
          "y" : 249
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1119,
          "y" : 249
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67156,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1102,
          "y" : 271
        },
        "to" : {
          "x" : 1111,
          "y" : 297
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1100,
            "y" : 278
          },
          "b" : {
            "x" : 1112,
            "y" : 290
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1106,
            "y" : 284
          }
        }
      }
    }, {
      "edgeId" : 67162,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1100,
          "y" : 241
        },
        "to" : {
          "x" : 1103,
          "y" : 217
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1095,
            "y" : 223
          },
          "b" : {
            "x" : 1107,
            "y" : 235
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1101,
            "y" : 229
          }
        }
      }
    } ]
  }, {
    "id" : 67159,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1193,
      "y" : 253
    },
    "minX" : 1172,
    "maxX" : 1214,
    "minY" : 217,
    "maxY" : 296,
    "prop" : {
      "x" : 1174,
      "y" : 242,
      "width" : 39,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1177,
      "y" : 242
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1208,
          "y" : 247
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1208,
          "y" : 247
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67156,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1187,
          "y" : 267
        },
        "to" : {
          "x" : 1172,
          "y" : 296
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1173,
            "y" : 275
          },
          "b" : {
            "x" : 1185,
            "y" : 287
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1179,
            "y" : 281
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1187,
          "y" : 275
        },
        "b" : {
          "x" : 1187,
          "y" : 267
        },
        "c" : {
          "x" : 1180,
          "y" : 271
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1180,
          "y" : 271
        }
      }
    }, {
      "edgeId" : 67162,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1187,
          "y" : 239
        },
        "to" : {
          "x" : 1174,
          "y" : 217
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1174,
            "y" : 222
          },
          "b" : {
            "x" : 1186,
            "y" : 234
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1180,
            "y" : 228
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1180,
          "y" : 235
        },
        "b" : {
          "x" : 1187,
          "y" : 239
        },
        "c" : {
          "x" : 1187,
          "y" : 231
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1187,
          "y" : 231
        }
      }
    } ]
  }, {
    "id" : 67158,
    "reactomeId" : 10141692,
    "displayName" : "Elavl1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1018,
      "y" : 267
    },
    "minX" : 987,
    "maxX" : 1111,
    "minY" : 217,
    "maxY" : 401,
    "prop" : {
      "x" : 987,
      "y" : 252,
      "width" : 63,
      "height" : 31
    },
    "textPosition" : {
      "x" : 996,
      "y" : 257
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1050,
          "y" : 252
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1050,
          "y" : 252
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67156,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1053,
          "y" : 277
        },
        "to" : {
          "x" : 1111,
          "y" : 297
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67162,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1044,
          "y" : 249
        },
        "to" : {
          "x" : 1103,
          "y" : 217
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67171,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1028,
          "y" : 286
        },
        "to" : {
          "x" : 1105,
          "y" : 401
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67161,
    "reactomeId" : 10141838,
    "displayName" : "PRKCA",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1139,
      "y" : 335
    },
    "minX" : 1107,
    "maxX" : 1178,
    "minY" : 304,
    "maxY" : 348,
    "prop" : {
      "x" : 1107,
      "y" : 323,
      "width" : 65,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1116,
      "y" : 325
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1172,
          "y" : 323
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1172,
          "y" : 323
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67156,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1139,
          "y" : 320
        },
        "to" : {
          "x" : 1139,
          "y" : 312
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1140,
          "y" : 308
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1140,
          "y" : 308
        }
      }
    } ]
  }, {
    "id" : 67160,
    "reactomeId" : 10141698,
    "displayName" : "phospho-Elavl1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1271,
      "y" : 306
    },
    "minX" : 1172,
    "maxX" : 1362,
    "minY" : 281,
    "maxY" : 329,
    "prop" : {
      "x" : 1217,
      "y" : 287,
      "width" : 108,
      "height" : 39
    },
    "textPosition" : {
      "x" : 1219,
      "y" : 296
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1325,
          "y" : 287
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1325,
          "y" : 287
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67156,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1214,
          "y" : 300
        },
        "to" : {
          "x" : 1172,
          "y" : 296
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1207,
          "y" : 303
        },
        "b" : {
          "x" : 1214,
          "y" : 300
        },
        "c" : {
          "x" : 1207,
          "y" : 295
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1207,
          "y" : 295
        }
      }
    }, {
      "edgeId" : 67165,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1328,
          "y" : 319
        },
        "to" : {
          "x" : 1362,
          "y" : 329
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67163,
    "reactomeId" : 10141703,
    "displayName" : "phospho-Elavl1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1286,
      "y" : 160
    },
    "minX" : 1174,
    "maxX" : 1370,
    "minY" : 135,
    "maxY" : 217,
    "prop" : {
      "x" : 1227,
      "y" : 141,
      "width" : 118,
      "height" : 38
    },
    "textPosition" : {
      "x" : 1234,
      "y" : 149
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1345,
          "y" : 141
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1345,
          "y" : 141
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67162,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1248,
          "y" : 182
        },
        "to" : {
          "x" : 1174,
          "y" : 217
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1243,
          "y" : 189
        },
        "b" : {
          "x" : 1248,
          "y" : 182
        },
        "c" : {
          "x" : 1240,
          "y" : 181
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1240,
          "y" : 181
        }
      }
    }, {
      "edgeId" : 67168,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1348,
          "y" : 145
        },
        "to" : {
          "x" : 1370,
          "y" : 139
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67164,
    "reactomeId" : 10141833,
    "displayName" : "PRKCD(1-676)",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1136,
      "y" : 173
    },
    "minX" : 1084,
    "maxX" : 1195,
    "minY" : 154,
    "maxY" : 207,
    "prop" : {
      "x" : 1084,
      "y" : 160,
      "width" : 105,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1089,
      "y" : 163
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1189,
          "y" : 160
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1189,
          "y" : 160
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67162,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1136,
          "y" : 190
        },
        "to" : {
          "x" : 1136,
          "y" : 199
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1136,
          "y" : 203
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1136,
          "y" : 203
        }
      }
    } ]
  }, {
    "id" : 67167,
    "reactomeId" : 10141700,
    "displayName" : "HuR with phosphoserine221 and phosphoserine158:mRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1473,
      "y" : 327
    },
    "minX" : 1410,
    "maxX" : 1542,
    "minY" : 284,
    "maxY" : 365,
    "prop" : {
      "x" : 1410,
      "y" : 290,
      "width" : 126,
      "height" : 75
    },
    "textPosition" : {
      "x" : 1408,
      "y" : 288
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1536,
          "y" : 290
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1536,
          "y" : 290
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67165,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67166,
    "reactomeId" : 450605,
    "displayName" : "mRNA Transcript Targeted by HuR Phosphorylated on Ser158 and Ser318.",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1287,
      "y" : 382
    },
    "minX" : 1220,
    "maxX" : 1362,
    "minY" : 329,
    "maxY" : 417,
    "prop" : {
      "x" : 1220,
      "y" : 347,
      "width" : 134,
      "height" : 70
    },
    "textPosition" : {
      "x" : 1220,
      "y" : 350
    },
    "connectors" : [ {
      "edgeId" : 67165,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1336,
          "y" : 344
        },
        "to" : {
          "x" : 1362,
          "y" : 329
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67169,
    "reactomeId" : 517622,
    "displayName" : "mRNA Transcript Targeted by HuR Phosphorylated on Ser221 and Ser318",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1304,
      "y" : 81
    },
    "minX" : 1214,
    "maxX" : 1395,
    "minY" : 56,
    "maxY" : 139,
    "prop" : {
      "x" : 1214,
      "y" : 56,
      "width" : 181,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1216,
      "y" : 56
    },
    "connectors" : [ {
      "edgeId" : 67168,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1332,
          "y" : 109
        },
        "to" : {
          "x" : 1370,
          "y" : 139
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67170,
    "reactomeId" : 10141705,
    "displayName" : "HuR with phosphoserine221 and phosphoserine318:mRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1485,
      "y" : 177
    },
    "minX" : 1426,
    "maxX" : 1551,
    "minY" : 130,
    "maxY" : 218,
    "prop" : {
      "x" : 1426,
      "y" : 136,
      "width" : 119,
      "height" : 82
    },
    "textPosition" : {
      "x" : 1426,
      "y" : 141
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1545,
          "y" : 136
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1545,
          "y" : 136
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67168,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67173,
    "reactomeId" : 10141694,
    "displayName" : "HuR with Unknown Phosphorylation: mRNA Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1438,
      "y" : 451
    },
    "minX" : 1370,
    "maxX" : 1513,
    "minY" : 420,
    "maxY" : 477,
    "prop" : {
      "x" : 1370,
      "y" : 426,
      "width" : 137,
      "height" : 51
    },
    "textPosition" : {
      "x" : 1375,
      "y" : 428
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1507,
          "y" : 426
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1507,
          "y" : 426
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67171,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67172,
    "reactomeId" : 450613,
    "displayName" : "mRNA Transcript Targeted by HuR with Unknown Phosphorylation",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1074,
      "y" : 454
    },
    "minX" : 993,
    "maxX" : 1156,
    "minY" : 401,
    "maxY" : 486,
    "prop" : {
      "x" : 993,
      "y" : 422,
      "width" : 163,
      "height" : 64
    },
    "textPosition" : {
      "x" : 1002,
      "y" : 422
    },
    "connectors" : [ {
      "edgeId" : 67171,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1092,
          "y" : 419
        },
        "to" : {
          "x" : 1105,
          "y" : 401
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67175,
    "reactomeId" : 10141685,
    "displayName" : "Set",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1629,
      "y" : 138
    },
    "minX" : 1603,
    "maxX" : 1662,
    "minY" : 116,
    "maxY" : 323,
    "prop" : {
      "x" : 1603,
      "y" : 122,
      "width" : 53,
      "height" : 32
    },
    "textPosition" : {
      "x" : 1615,
      "y" : 127
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1656,
          "y" : 122
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1656,
          "y" : 122
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67174,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1631,
          "y" : 157
        },
        "to" : {
          "x" : 1657,
          "y" : 323
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67177,
    "reactomeId" : 10141677,
    "displayName" : "Anp32a",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1679,
      "y" : 95
    },
    "minX" : 1644,
    "maxX" : 1721,
    "minY" : 76,
    "maxY" : 323,
    "prop" : {
      "x" : 1644,
      "y" : 82,
      "width" : 71,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1651,
      "y" : 85
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1715,
          "y" : 82
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1715,
          "y" : 82
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67174,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1677,
          "y" : 112
        },
        "to" : {
          "x" : 1657,
          "y" : 323
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67176,
    "reactomeId" : 10141673,
    "displayName" : "phospho-Tnfsf13",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1559,
      "y" : 95
    },
    "minX" : 1495,
    "maxX" : 1657,
    "minY" : 74,
    "maxY" : 323,
    "prop" : {
      "x" : 1495,
      "y" : 80,
      "width" : 128,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1502,
      "y" : 84
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1623,
          "y" : 80
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1623,
          "y" : 80
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67174,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1565,
          "y" : 113
        },
        "to" : {
          "x" : 1657,
          "y" : 323
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67179,
    "reactomeId" : 10141679,
    "displayName" : "Nup214",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1724,
      "y" : 299
    },
    "minX" : 1657,
    "maxX" : 1766,
    "minY" : 276,
    "maxY" : 323,
    "prop" : {
      "x" : 1688,
      "y" : 282,
      "width" : 72,
      "height" : 34
    },
    "textPosition" : {
      "x" : 1695,
      "y" : 288
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1760,
          "y" : 282
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1760,
          "y" : 282
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67174,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1685,
          "y" : 311
        },
        "to" : {
          "x" : 1657,
          "y" : 323
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67178,
    "reactomeId" : 10141707,
    "displayName" : "HuR:mRNA complexes",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1594,
      "y" : 321
    },
    "minX" : 1557,
    "maxX" : 1657,
    "minY" : 301,
    "maxY" : 341,
    "prop" : {
      "x" : 1557,
      "y" : 301,
      "width" : 75,
      "height" : 40
    },
    "textPosition" : {
      "x" : 1556,
      "y" : 303
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 67174,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1638,
          "y" : 322
        },
        "to" : {
          "x" : 1657,
          "y" : 323
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67181,
    "reactomeId" : 10141709,
    "displayName" : "HuR:APRIL:pp32:SET(SETalpha):Nup214(SETbeta):CRM1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1659,
      "y" : 438
    },
    "minX" : 1604,
    "maxX" : 1720,
    "minY" : 398,
    "maxY" : 472,
    "prop" : {
      "x" : 1604,
      "y" : 404,
      "width" : 110,
      "height" : 68
    },
    "textPosition" : {
      "x" : 1604,
      "y" : 409
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1714,
          "y" : 404
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1714,
          "y" : 404
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67174,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 67182,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67180,
    "reactomeId" : 10117702,
    "displayName" : "Xpo1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1723,
      "y" : 144
    },
    "minX" : 1657,
    "maxX" : 1756,
    "minY" : 126,
    "maxY" : 323,
    "prop" : {
      "x" : 1697,
      "y" : 132,
      "width" : 53,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1704,
      "y" : 133
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1750,
          "y" : 132
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1750,
          "y" : 132
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67174,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1718,
          "y" : 159
        },
        "to" : {
          "x" : 1657,
          "y" : 323
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 67183,
    "reactomeId" : 10141865,
    "displayName" : "phospho-Tnfsf13",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1584,
      "y" : 591
    },
    "minX" : 1524,
    "maxX" : 1659,
    "minY" : 555,
    "maxY" : 608,
    "prop" : {
      "x" : 1524,
      "y" : 575,
      "width" : 120,
      "height" : 33
    },
    "textPosition" : {
      "x" : 1527,
      "y" : 581
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1644,
          "y" : 575
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1644,
          "y" : 575
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 67182,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1618,
          "y" : 572
        },
        "to" : {
          "x" : 1659,
          "y" : 555
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1623,
          "y" : 566
        },
        "b" : {
          "x" : 1618,
          "y" : 572
        },
        "c" : {
          "x" : 1626,
          "y" : 573
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1626,
          "y" : 573
        }
      }
    } ]
  }, {
    "id" : 67184,
    "reactomeId" : 10141881,
    "displayName" : "HuR:mRNA Complex",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1699,
      "y" : 599
    },
    "minX" : 1659,
    "maxX" : 1737,
    "minY" : 555,
    "maxY" : 618,
    "prop" : {
      "x" : 1661,
      "y" : 580,
      "width" : 76,
      "height" : 38
    },
    "textPosition" : {
      "x" : 1661,
      "y" : 581
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 67182,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1681,
          "y" : 574
        },
        "to" : {
          "x" : 1659,
          "y" : 555
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1673,
          "y" : 572
        },
        "b" : {
          "x" : 1681,
          "y" : 574
        },
        "c" : {
          "x" : 1678,
          "y" : 566
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1678,
          "y" : 566
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 67136,
    "reactomeId" : 10141790,
    "displayName" : "MK2 phosphorylates ZFP36 (Tristetraproline, TTP)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 901,
      "y" : 845
    },
    "minX" : 865,
    "maxX" : 945,
    "minY" : 839,
    "maxY" : 851,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 865,
        "y" : 846
      },
      "to" : {
        "x" : 901,
        "y" : 845
      }
    }, {
      "from" : {
        "x" : 901,
        "y" : 845
      },
      "to" : {
        "x" : 945,
        "y" : 846
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 895,
        "y" : 839
      },
      "b" : {
        "x" : 907,
        "y" : 851
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 901,
        "y" : 845
      }
    },
    "inputs" : [ {
      "id" : 67137,
      "points" : [ {
        "x" : 842,
        "y" : 873
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 67133,
      "points" : [ {
        "x" : 368,
        "y" : 657
      }, {
        "x" : 352,
        "y" : 657
      }, {
        "x" : 350,
        "y" : 843
      } ]
    } ],
    "outputs" : [ {
      "id" : 67138,
      "points" : [ {
        "x" : 1001,
        "y" : 846
      } ]
    }, {
      "id" : 67139,
      "points" : [ {
        "x" : 967,
        "y" : 870
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 67123,
      "points" : [ {
        "x" : 901,
        "y" : 804
      } ]
    } ]
  }, {
    "id" : 67140,
    "reactomeId" : 10141727,
    "displayName" : "p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1228,
      "y" : 849
    },
    "minX" : 1203,
    "maxX" : 1252,
    "minY" : 843,
    "maxY" : 855,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1203,
        "y" : 848
      },
      "to" : {
        "x" : 1228,
        "y" : 849
      }
    }, {
      "from" : {
        "x" : 1228,
        "y" : 849
      },
      "to" : {
        "x" : 1252,
        "y" : 847
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1245,
        "y" : 852
      },
      "b" : {
        "x" : 1252,
        "y" : 847
      },
      "c" : {
        "x" : 1245,
        "y" : 844
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1245,
        "y" : 844
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1228,
        "y" : 849
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1228,
        "y" : 849
      }
    },
    "inputs" : [ {
      "id" : 67125,
      "points" : [ {
        "x" : 1170,
        "y" : 799
      } ]
    }, {
      "id" : 67138,
      "points" : [ {
        "x" : 1107,
        "y" : 847
      } ]
    } ],
    "outputs" : [ {
      "id" : 67141
    } ]
  }, {
    "id" : 67142,
    "reactomeId" : 10141863,
    "displayName" : "KSRP binds AU-rich element in 3' UTR of mRNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 447,
      "y" : 238
    },
    "minX" : 441,
    "maxX" : 453,
    "minY" : 213,
    "maxY" : 266,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 446,
        "y" : 213
      },
      "to" : {
        "x" : 447,
        "y" : 238
      }
    }, {
      "from" : {
        "x" : 447,
        "y" : 238
      },
      "to" : {
        "x" : 447,
        "y" : 266
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 443,
        "y" : 259
      },
      "b" : {
        "x" : 447,
        "y" : 266
      },
      "c" : {
        "x" : 451,
        "y" : 259
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 451,
        "y" : 259
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 447,
        "y" : 238
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 447,
        "y" : 238
      }
    },
    "inputs" : [ {
      "id" : 67143,
      "points" : [ {
        "x" : 471,
        "y" : 203
      } ]
    }, {
      "id" : 67144,
      "points" : [ {
        "x" : 409,
        "y" : 200
      } ]
    } ],
    "outputs" : [ {
      "id" : 67145
    } ]
  }, {
    "id" : 67146,
    "reactomeId" : 10141762,
    "displayName" : "KSRP recruits RNA degradation activities",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 446,
      "y" : 363
    },
    "minX" : 440,
    "maxX" : 452,
    "minY" : 340,
    "maxY" : 391,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 446,
        "y" : 340
      },
      "to" : {
        "x" : 446,
        "y" : 363
      }
    }, {
      "from" : {
        "x" : 446,
        "y" : 363
      },
      "to" : {
        "x" : 446,
        "y" : 391
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 442,
        "y" : 384
      },
      "b" : {
        "x" : 446,
        "y" : 391
      },
      "c" : {
        "x" : 450,
        "y" : 384
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 450,
        "y" : 384
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 446,
        "y" : 363
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 446,
        "y" : 363
      }
    },
    "inputs" : [ {
      "id" : 67147,
      "points" : [ {
        "x" : 381,
        "y" : 310
      } ]
    }, {
      "id" : 67113,
      "points" : [ {
        "x" : 569,
        "y" : 644
      }, {
        "x" : 533,
        "y" : 320
      } ]
    }, {
      "id" : 67145,
      "points" : [ {
        "x" : 446,
        "y" : 310
      } ]
    }, {
      "id" : 67114,
      "points" : [ {
        "x" : 616,
        "y" : 576
      }, {
        "x" : 540,
        "y" : 294
      } ]
    } ],
    "outputs" : [ {
      "id" : 67148
    } ]
  }, {
    "id" : 67149,
    "reactomeId" : 10141829,
    "displayName" : "Protein Kinase B (AKT) phosphorylates KSRP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 647,
      "y" : 234
    },
    "minX" : 593,
    "maxX" : 687,
    "minY" : 228,
    "maxY" : 240,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 593,
        "y" : 234
      },
      "to" : {
        "x" : 647,
        "y" : 234
      }
    }, {
      "from" : {
        "x" : 647,
        "y" : 234
      },
      "to" : {
        "x" : 687,
        "y" : 234
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 641,
        "y" : 228
      },
      "b" : {
        "x" : 653,
        "y" : 240
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 647,
        "y" : 234
      }
    },
    "inputs" : [ {
      "id" : 67143,
      "points" : [ {
        "x" : 516,
        "y" : 199
      } ]
    }, {
      "id" : 67150,
      "points" : [ {
        "x" : 576,
        "y" : 203
      } ]
    } ],
    "outputs" : [ {
      "id" : 67151,
      "points" : [ {
        "x" : 766,
        "y" : 230
      } ]
    }, {
      "id" : 67152,
      "points" : [ {
        "x" : 711,
        "y" : 200
      } ]
    } ],
    "catalysts" : [ {
      "id" : 67120,
      "points" : [ {
        "x" : 902,
        "y" : 530
      }, {
        "x" : 648,
        "y" : 265
      } ]
    } ]
  }, {
    "id" : 67153,
    "reactomeId" : 10141891,
    "displayName" : "p-S193-KSRP binds 14-3-3zeta in the nucleus",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1061,
      "y" : 86
    },
    "minX" : 1037,
    "maxX" : 1096,
    "minY" : 80,
    "maxY" : 92,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1037,
        "y" : 86
      },
      "to" : {
        "x" : 1061,
        "y" : 86
      }
    }, {
      "from" : {
        "x" : 1061,
        "y" : 86
      },
      "to" : {
        "x" : 1096,
        "y" : 86
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1089,
        "y" : 90
      },
      "b" : {
        "x" : 1096,
        "y" : 86
      },
      "c" : {
        "x" : 1089,
        "y" : 82
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1089,
        "y" : 82
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1055,
        "y" : 80
      },
      "b" : {
        "x" : 1067,
        "y" : 92
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1061,
        "y" : 86
      }
    },
    "inputs" : [ {
      "id" : 67151,
      "points" : [ {
        "x" : 847,
        "y" : 207
      } ]
    }, {
      "id" : 67154,
      "points" : [ {
        "x" : 1031,
        "y" : 74
      } ]
    } ],
    "outputs" : [ {
      "id" : 67155
    } ]
  }, {
    "id" : 67090,
    "reactomeId" : 10141788,
    "displayName" : "AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 149,
      "y" : 160
    },
    "minX" : 143,
    "maxX" : 155,
    "minY" : 136,
    "maxY" : 184,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 150,
        "y" : 136
      },
      "to" : {
        "x" : 149,
        "y" : 160
      }
    }, {
      "from" : {
        "x" : 149,
        "y" : 160
      },
      "to" : {
        "x" : 149,
        "y" : 184
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 145,
        "y" : 177
      },
      "b" : {
        "x" : 149,
        "y" : 184
      },
      "c" : {
        "x" : 153,
        "y" : 177
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 153,
        "y" : 177
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 149,
        "y" : 160
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 149,
        "y" : 160
      }
    },
    "inputs" : [ {
      "id" : 67091,
      "points" : [ {
        "x" : 185,
        "y" : 105
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 67092,
      "points" : [ {
        "x" : 115,
        "y" : 104
      } ]
    } ],
    "outputs" : [ {
      "id" : 67093
    } ]
  }, {
    "id" : 67156,
    "reactomeId" : 10141841,
    "displayName" : "PKCalpha phosphorylates HuR",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1140,
      "y" : 296
    },
    "minX" : 1111,
    "maxX" : 1172,
    "minY" : 290,
    "maxY" : 302,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1111,
        "y" : 297
      },
      "to" : {
        "x" : 1140,
        "y" : 296
      }
    }, {
      "from" : {
        "x" : 1140,
        "y" : 296
      },
      "to" : {
        "x" : 1172,
        "y" : 296
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1134,
        "y" : 290
      },
      "b" : {
        "x" : 1146,
        "y" : 302
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1140,
        "y" : 296
      }
    },
    "inputs" : [ {
      "id" : 67157,
      "points" : [ {
        "x" : 1102,
        "y" : 271
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 67158,
      "points" : [ {
        "x" : 1053,
        "y" : 277
      } ]
    } ],
    "outputs" : [ {
      "id" : 67159,
      "points" : [ {
        "x" : 1187,
        "y" : 267
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 67160,
      "points" : [ {
        "x" : 1214,
        "y" : 300
      } ]
    } ],
    "catalysts" : [ {
      "id" : 67161,
      "points" : [ {
        "x" : 1139,
        "y" : 320
      } ]
    } ]
  }, {
    "id" : 67094,
    "reactomeId" : 10141859,
    "displayName" : "AUF1 binds translation and heat shock proteins",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 149,
      "y" : 301
    },
    "minX" : 121,
    "maxX" : 155,
    "minY" : 279,
    "maxY" : 322,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 121,
        "y" : 279
      },
      "to" : {
        "x" : 149,
        "y" : 301
      }
    }, {
      "from" : {
        "x" : 149,
        "y" : 301
      },
      "to" : {
        "x" : 149,
        "y" : 322
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 145,
        "y" : 315
      },
      "b" : {
        "x" : 149,
        "y" : 322
      },
      "c" : {
        "x" : 153,
        "y" : 315
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 153,
        "y" : 315
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 149,
        "y" : 301
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 149,
        "y" : 301
      }
    },
    "inputs" : [ {
      "id" : 67095,
      "points" : [ {
        "x" : 82,
        "y" : 261
      } ]
    }, {
      "id" : 67096,
      "points" : [ {
        "x" : 160,
        "y" : 265
      } ]
    }, {
      "id" : 67097,
      "points" : [ {
        "x" : 95,
        "y" : 276
      } ]
    }, {
      "id" : 67098,
      "points" : [ {
        "x" : 93,
        "y" : 290
      } ]
    }, {
      "id" : 67099,
      "points" : [ {
        "x" : 162,
        "y" : 277
      } ]
    }, {
      "id" : 67093,
      "points" : [ {
        "x" : 139,
        "y" : 238
      } ]
    } ],
    "outputs" : [ {
      "id" : 67100
    } ]
  }, {
    "id" : 67162,
    "reactomeId" : 10141836,
    "displayName" : "PKCdelta phosphorylates HuR",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1136,
      "y" : 215
    },
    "minX" : 1103,
    "maxX" : 1174,
    "minY" : 209,
    "maxY" : 221,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1103,
        "y" : 217
      },
      "to" : {
        "x" : 1136,
        "y" : 215
      }
    }, {
      "from" : {
        "x" : 1136,
        "y" : 215
      },
      "to" : {
        "x" : 1174,
        "y" : 217
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1130,
        "y" : 209
      },
      "b" : {
        "x" : 1142,
        "y" : 221
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1136,
        "y" : 215
      }
    },
    "inputs" : [ {
      "id" : 67158,
      "points" : [ {
        "x" : 1044,
        "y" : 249
      } ]
    }, {
      "id" : 67157,
      "points" : [ {
        "x" : 1100,
        "y" : 241
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 67163,
      "points" : [ {
        "x" : 1248,
        "y" : 182
      } ]
    }, {
      "id" : 67159,
      "points" : [ {
        "x" : 1187,
        "y" : 239
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 67164,
      "points" : [ {
        "x" : 1136,
        "y" : 190
      } ]
    } ]
  }, {
    "id" : 67165,
    "reactomeId" : 10143290,
    "displayName" : "p-S158,221-HuR binds mRNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1382,
      "y" : 329
    },
    "minX" : 1362,
    "maxX" : 1407,
    "minY" : 323,
    "maxY" : 335,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1362,
        "y" : 329
      },
      "to" : {
        "x" : 1382,
        "y" : 329
      }
    }, {
      "from" : {
        "x" : 1382,
        "y" : 329
      },
      "to" : {
        "x" : 1407,
        "y" : 328
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1400,
        "y" : 332
      },
      "b" : {
        "x" : 1407,
        "y" : 328
      },
      "c" : {
        "x" : 1400,
        "y" : 324
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1400,
        "y" : 324
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1382,
        "y" : 329
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1382,
        "y" : 329
      }
    },
    "inputs" : [ {
      "id" : 67160,
      "points" : [ {
        "x" : 1328,
        "y" : 319
      } ]
    }, {
      "id" : 67166,
      "points" : [ {
        "x" : 1336,
        "y" : 344
      } ]
    } ],
    "outputs" : [ {
      "id" : 67167
    } ]
  }, {
    "id" : 67101,
    "reactomeId" : 10141861,
    "displayName" : "AUF1 (hnRNP D0) is ubiquitinylated",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 149,
      "y" : 440
    },
    "minX" : 143,
    "maxX" : 155,
    "minY" : 424,
    "maxY" : 468,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 148,
        "y" : 424
      },
      "to" : {
        "x" : 149,
        "y" : 440
      }
    }, {
      "from" : {
        "x" : 149,
        "y" : 440
      },
      "to" : {
        "x" : 149,
        "y" : 468
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 145,
        "y" : 461
      },
      "b" : {
        "x" : 149,
        "y" : 468
      },
      "c" : {
        "x" : 153,
        "y" : 461
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 153,
        "y" : 461
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 143,
        "y" : 434
      },
      "b" : {
        "x" : 155,
        "y" : 446
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 149,
        "y" : 440
      }
    },
    "inputs" : [ {
      "id" : 67102,
      "points" : [ {
        "x" : 101,
        "y" : 416
      } ],
      "stoichiometry" : 4
    }, {
      "id" : 67100,
      "points" : [ {
        "x" : 148,
        "y" : 393
      } ]
    } ],
    "outputs" : [ {
      "id" : 67103
    } ]
  }, {
    "id" : 67168,
    "reactomeId" : 10143292,
    "displayName" : "p-S318,221-HuR binds mRNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1396,
      "y" : 138
    },
    "minX" : 1370,
    "maxX" : 1423,
    "minY" : 132,
    "maxY" : 150,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1370,
        "y" : 139
      },
      "to" : {
        "x" : 1396,
        "y" : 138
      }
    }, {
      "from" : {
        "x" : 1396,
        "y" : 138
      },
      "to" : {
        "x" : 1423,
        "y" : 150
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1415,
        "y" : 151
      },
      "b" : {
        "x" : 1423,
        "y" : 150
      },
      "c" : {
        "x" : 1418,
        "y" : 144
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1418,
        "y" : 144
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1396,
        "y" : 138
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1396,
        "y" : 138
      }
    },
    "inputs" : [ {
      "id" : 67169,
      "points" : [ {
        "x" : 1332,
        "y" : 109
      } ]
    }, {
      "id" : 67163,
      "points" : [ {
        "x" : 1348,
        "y" : 145
      } ]
    } ],
    "outputs" : [ {
      "id" : 67170
    } ]
  }, {
    "id" : 67104,
    "reactomeId" : 10141803,
    "displayName" : "AUF1:mRNA complex is degraded",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 148,
      "y" : 565
    },
    "minX" : 61,
    "maxX" : 154,
    "minY" : 429,
    "maxY" : 571,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 148,
        "y" : 539
      },
      "to" : {
        "x" : 148,
        "y" : 565
      }
    }, {
      "from" : {
        "x" : 148,
        "y" : 565
      },
      "to" : {
        "x" : 61,
        "y" : 567
      }
    }, {
      "from" : {
        "x" : 61,
        "y" : 567
      },
      "to" : {
        "x" : 63,
        "y" : 429
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 67,
        "y" : 436
      },
      "b" : {
        "x" : 63,
        "y" : 429
      },
      "c" : {
        "x" : 59,
        "y" : 436
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 59,
        "y" : 436
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 142,
        "y" : 559
      },
      "b" : {
        "x" : 154,
        "y" : 571
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 148,
        "y" : 565
      }
    },
    "inputs" : [ {
      "id" : 67103
    } ],
    "outputs" : [ {
      "id" : 67102,
      "stoichiometry" : 12
    } ],
    "catalysts" : [ {
      "id" : 67105,
      "points" : [ {
        "x" : 191,
        "y" : 564
      } ]
    } ]
  }, {
    "id" : 67171,
    "reactomeId" : 10141824,
    "displayName" : "HuR binds mRNAs in the nucleus",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1311,
      "y" : 450
    },
    "minX" : 1105,
    "maxX" : 1367,
    "minY" : 401,
    "maxY" : 456,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1105,
        "y" : 401
      },
      "to" : {
        "x" : 1311,
        "y" : 450
      }
    }, {
      "from" : {
        "x" : 1311,
        "y" : 450
      },
      "to" : {
        "x" : 1367,
        "y" : 450
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1360,
        "y" : 454
      },
      "b" : {
        "x" : 1367,
        "y" : 450
      },
      "c" : {
        "x" : 1360,
        "y" : 446
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1360,
        "y" : 446
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1311,
        "y" : 450
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1311,
        "y" : 450
      }
    },
    "inputs" : [ {
      "id" : 67158,
      "points" : [ {
        "x" : 1028,
        "y" : 286
      } ]
    }, {
      "id" : 67172,
      "points" : [ {
        "x" : 1092,
        "y" : 419
      } ]
    } ],
    "outputs" : [ {
      "id" : 67173
    } ]
  }, {
    "id" : 67106,
    "reactomeId" : 10141831,
    "displayName" : "Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 744,
      "y" : 602
    },
    "minX" : 738,
    "maxX" : 750,
    "minY" : 580,
    "maxY" : 628,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 743,
        "y" : 580
      },
      "to" : {
        "x" : 744,
        "y" : 602
      }
    }, {
      "from" : {
        "x" : 744,
        "y" : 602
      },
      "to" : {
        "x" : 744,
        "y" : 628
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 740,
        "y" : 621
      },
      "b" : {
        "x" : 744,
        "y" : 628
      },
      "c" : {
        "x" : 748,
        "y" : 621
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 748,
        "y" : 621
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 744,
        "y" : 602
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 744,
        "y" : 602
      }
    },
    "inputs" : [ {
      "id" : 67107,
      "points" : [ {
        "x" : 707,
        "y" : 555
      } ]
    }, {
      "id" : 67108,
      "points" : [ {
        "x" : 778,
        "y" : 554
      } ]
    } ],
    "outputs" : [ {
      "id" : 67109
    } ]
  }, {
    "id" : 67110,
    "reactomeId" : 10141819,
    "displayName" : "BRF1 Complex recruits RNA degradation activities",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 743,
      "y" : 736
    },
    "minX" : 737,
    "maxX" : 749,
    "minY" : 711,
    "maxY" : 760,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 742,
        "y" : 711
      },
      "to" : {
        "x" : 743,
        "y" : 736
      }
    }, {
      "from" : {
        "x" : 743,
        "y" : 736
      },
      "to" : {
        "x" : 742,
        "y" : 760
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 738,
        "y" : 753
      },
      "b" : {
        "x" : 742,
        "y" : 760
      },
      "c" : {
        "x" : 746,
        "y" : 753
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 746,
        "y" : 753
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 743,
        "y" : 736
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 743,
        "y" : 736
      }
    },
    "inputs" : [ {
      "id" : 67111,
      "points" : [ {
        "x" : 611,
        "y" : 729
      } ]
    }, {
      "id" : 67112,
      "points" : [ {
        "x" : 608,
        "y" : 701
      } ]
    }, {
      "id" : 67113,
      "points" : [ {
        "x" : 609,
        "y" : 673
      } ]
    }, {
      "id" : 67109,
      "points" : [ {
        "x" : 744,
        "y" : 668
      } ]
    }, {
      "id" : 67114,
      "points" : [ {
        "x" : 632,
        "y" : 607
      } ]
    } ],
    "outputs" : [ {
      "id" : 67115
    } ]
  }, {
    "id" : 67174,
    "reactomeId" : 10141711,
    "displayName" : "HuR binds the CRM1 nuclear export machinery",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1657,
      "y" : 371
    },
    "minX" : 1651,
    "maxX" : 1663,
    "minY" : 323,
    "maxY" : 401,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1657,
        "y" : 323
      },
      "to" : {
        "x" : 1657,
        "y" : 371
      }
    }, {
      "from" : {
        "x" : 1657,
        "y" : 371
      },
      "to" : {
        "x" : 1657,
        "y" : 401
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1653,
        "y" : 394
      },
      "b" : {
        "x" : 1657,
        "y" : 401
      },
      "c" : {
        "x" : 1661,
        "y" : 394
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1661,
        "y" : 394
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1657,
        "y" : 371
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1657,
        "y" : 371
      }
    },
    "inputs" : [ {
      "id" : 67175,
      "points" : [ {
        "x" : 1631,
        "y" : 157
      } ]
    }, {
      "id" : 67176,
      "points" : [ {
        "x" : 1565,
        "y" : 113
      } ]
    }, {
      "id" : 67177,
      "points" : [ {
        "x" : 1677,
        "y" : 112
      } ]
    }, {
      "id" : 67178,
      "points" : [ {
        "x" : 1638,
        "y" : 322
      } ]
    }, {
      "id" : 67179,
      "points" : [ {
        "x" : 1685,
        "y" : 311
      } ]
    }, {
      "id" : 67180,
      "points" : [ {
        "x" : 1718,
        "y" : 159
      } ]
    } ],
    "outputs" : [ {
      "id" : 67181
    } ]
  }, {
    "id" : 67116,
    "reactomeId" : 10141822,
    "displayName" : "Protein Kinase B/Akt phosphorylates BRF1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 899,
      "y" : 611
    },
    "minX" : 860,
    "maxX" : 920,
    "minY" : 605,
    "maxY" : 617,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 860,
        "y" : 612
      },
      "to" : {
        "x" : 899,
        "y" : 611
      }
    }, {
      "from" : {
        "x" : 899,
        "y" : 611
      },
      "to" : {
        "x" : 920,
        "y" : 612
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 893,
        "y" : 605
      },
      "b" : {
        "x" : 905,
        "y" : 617
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 899,
        "y" : 611
      }
    },
    "inputs" : [ {
      "id" : 67117,
      "points" : [ {
        "x" : 840,
        "y" : 641
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 67109,
      "points" : [ {
        "x" : 790,
        "y" : 634
      } ]
    } ],
    "outputs" : [ {
      "id" : 67118,
      "points" : [ {
        "x" : 947,
        "y" : 639
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 67119,
      "points" : [ {
        "x" : 993,
        "y" : 611
      } ]
    } ],
    "catalysts" : [ {
      "id" : 67120,
      "points" : [ {
        "x" : 913,
        "y" : 568
      } ]
    } ]
  }, {
    "id" : 67182,
    "reactomeId" : 10141883,
    "displayName" : "HuR:mRNA complex translocates from the nucleus to the cytosol",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1658,
      "y" : 527
    },
    "minX" : 1652,
    "maxX" : 1664,
    "minY" : 475,
    "maxY" : 555,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1658,
        "y" : 475
      },
      "to" : {
        "x" : 1658,
        "y" : 527
      }
    }, {
      "from" : {
        "x" : 1658,
        "y" : 527
      },
      "to" : {
        "x" : 1659,
        "y" : 555
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1652,
        "y" : 521
      },
      "b" : {
        "x" : 1664,
        "y" : 533
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1658,
        "y" : 527
      }
    },
    "inputs" : [ {
      "id" : 67181
    } ],
    "outputs" : [ {
      "id" : 67183,
      "points" : [ {
        "x" : 1618,
        "y" : 572
      } ]
    }, {
      "id" : 67184,
      "points" : [ {
        "x" : 1681,
        "y" : 574
      } ]
    } ]
  }, {
    "id" : 67121,
    "reactomeId" : 10141815,
    "displayName" : "MK2 phosphorylates BRF1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 900,
      "y" : 703
    },
    "minX" : 860,
    "maxX" : 932,
    "minY" : 697,
    "maxY" : 709,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 860,
        "y" : 702
      },
      "to" : {
        "x" : 900,
        "y" : 703
      }
    }, {
      "from" : {
        "x" : 900,
        "y" : 703
      },
      "to" : {
        "x" : 932,
        "y" : 702
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 894,
        "y" : 697
      },
      "b" : {
        "x" : 906,
        "y" : 709
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 900,
        "y" : 703
      }
    },
    "inputs" : [ {
      "id" : 67109,
      "points" : [ {
        "x" : 781,
        "y" : 668
      } ]
    }, {
      "id" : 67117,
      "points" : [ {
        "x" : 840,
        "y" : 670
      } ],
      "stoichiometry" : 3
    } ],
    "outputs" : [ {
      "id" : 67122,
      "points" : [ {
        "x" : 986,
        "y" : 702
      } ]
    }, {
      "id" : 67118,
      "points" : [ {
        "x" : 952,
        "y" : 671
      } ],
      "stoichiometry" : 3
    } ],
    "catalysts" : [ {
      "id" : 67123,
      "points" : [ {
        "x" : 901,
        "y" : 743
      } ]
    } ]
  }, {
    "id" : 67124,
    "reactomeId" : 10141748,
    "displayName" : "p-S92,203-BRF1 binds 14-3-3",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1208,
      "y" : 612
    },
    "minX" : 1191,
    "maxX" : 1259,
    "minY" : 606,
    "maxY" : 618,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1191,
        "y" : 611
      },
      "to" : {
        "x" : 1208,
        "y" : 612
      }
    }, {
      "from" : {
        "x" : 1208,
        "y" : 612
      },
      "to" : {
        "x" : 1259,
        "y" : 611
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1252,
        "y" : 615
      },
      "b" : {
        "x" : 1259,
        "y" : 611
      },
      "c" : {
        "x" : 1252,
        "y" : 607
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1252,
        "y" : 607
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1208,
        "y" : 612
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1208,
        "y" : 612
      }
    },
    "inputs" : [ {
      "id" : 67125,
      "points" : [ {
        "x" : 1161,
        "y" : 754
      } ]
    }, {
      "id" : 67119,
      "points" : [ {
        "x" : 1112,
        "y" : 611
      } ]
    } ],
    "outputs" : [ {
      "id" : 67126
    } ]
  }, {
    "id" : 67127,
    "reactomeId" : 10143068,
    "displayName" : "p-S54,92,203-BRF1 binds 14-3-3",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1216,
      "y" : 702
    },
    "minX" : 1193,
    "maxX" : 1238,
    "minY" : 696,
    "maxY" : 708,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1193,
        "y" : 702
      },
      "to" : {
        "x" : 1216,
        "y" : 702
      }
    }, {
      "from" : {
        "x" : 1216,
        "y" : 702
      },
      "to" : {
        "x" : 1238,
        "y" : 701
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1231,
        "y" : 705
      },
      "b" : {
        "x" : 1238,
        "y" : 701
      },
      "c" : {
        "x" : 1231,
        "y" : 697
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1231,
        "y" : 697
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1216,
        "y" : 702
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1216,
        "y" : 702
      }
    },
    "inputs" : [ {
      "id" : 67122,
      "points" : [ {
        "x" : 1115,
        "y" : 702
      } ]
    }, {
      "id" : 67125,
      "points" : [ {
        "x" : 1167,
        "y" : 754
      } ]
    } ],
    "outputs" : [ {
      "id" : 67128
    } ]
  }, {
    "id" : 67129,
    "reactomeId" : 10141733,
    "displayName" : "ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 409,
      "y" : 610
    },
    "minX" : 403,
    "maxX" : 415,
    "minY" : 588,
    "maxY" : 635,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 410,
        "y" : 588
      },
      "to" : {
        "x" : 409,
        "y" : 610
      }
    }, {
      "from" : {
        "x" : 409,
        "y" : 610
      },
      "to" : {
        "x" : 409,
        "y" : 635
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 405,
        "y" : 628
      },
      "b" : {
        "x" : 409,
        "y" : 635
      },
      "c" : {
        "x" : 413,
        "y" : 628
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 413,
        "y" : 628
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 409,
        "y" : 610
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 409,
        "y" : 610
      }
    },
    "inputs" : [ {
      "id" : 67130,
      "points" : [ {
        "x" : 406,
        "y" : 523
      } ]
    }, {
      "id" : 67131,
      "points" : [ {
        "x" : 454,
        "y" : 567
      } ]
    }, {
      "id" : 67132,
      "points" : [ {
        "x" : 378,
        "y" : 574
      } ]
    } ],
    "outputs" : [ {
      "id" : 67133
    } ]
  }, {
    "id" : 67134,
    "reactomeId" : 10141770,
    "displayName" : "ZFP36 (TTP) recruits RNA degradation activities",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 408,
      "y" : 746
    },
    "minX" : 402,
    "maxX" : 415,
    "minY" : 721,
    "maxY" : 780,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 409,
        "y" : 721
      },
      "to" : {
        "x" : 408,
        "y" : 746
      }
    }, {
      "from" : {
        "x" : 408,
        "y" : 746
      },
      "to" : {
        "x" : 415,
        "y" : 780
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 410,
        "y" : 774
      },
      "b" : {
        "x" : 415,
        "y" : 780
      },
      "c" : {
        "x" : 418,
        "y" : 772
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 418,
        "y" : 772
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 408,
        "y" : 746
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 408,
        "y" : 746
      }
    },
    "inputs" : [ {
      "id" : 67112,
      "points" : [ {
        "x" : 553,
        "y" : 703
      } ]
    }, {
      "id" : 67111,
      "points" : [ {
        "x" : 550,
        "y" : 731
      } ]
    }, {
      "id" : 67113,
      "points" : [ {
        "x" : 533,
        "y" : 676
      } ]
    }, {
      "id" : 67114,
      "points" : [ {
        "x" : 599,
        "y" : 607
      } ]
    }, {
      "id" : 67133,
      "points" : [ {
        "x" : 409,
        "y" : 683
      } ]
    } ],
    "outputs" : [ {
      "id" : 67135
    } ]
  } ],
  "compartments" : [ {
    "id" : 67185,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 948,
      "y" : 477
    },
    "minX" : 0,
    "maxX" : 1896,
    "minY" : 0,
    "maxY" : 954,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 1896,
      "height" : 954
    },
    "textPosition" : {
      "x" : 1722,
      "y" : 903
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 1876,
      "height" : 934
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 67090, 67091, 67092, 67093, 67094, 67095, 67097, 67098, 67099, 67100, 67101, 67102, 67103, 67104, 67105, 67106, 67107, 67108, 67109, 67115, 67111, 67112, 67113, 67114, 67116, 67117, 67118, 67119, 67120, 67110, 67121, 67122, 67123, 67124, 67125, 67126, 67127, 67128, 67129, 67130, 67131, 67132, 67133, 67134, 67135, 67136, 67137, 67138, 67139, 67140, 67141, 67143, 67142, 67144, 67145, 67146, 67147, 67148, 67150, 67151, 67152, 67149, 67183, 67184, 67186, 67182, 67096 ]
  }, {
    "id" : 67186,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1420,
      "y" : 271
    },
    "minX" : 964,
    "maxX" : 1876,
    "minY" : 31,
    "maxY" : 511,
    "prop" : {
      "x" : 964,
      "y" : 31,
      "width" : 912,
      "height" : 480
    },
    "textPosition" : {
      "x" : 1758,
      "y" : 467
    },
    "insets" : {
      "x" : 974,
      "y" : 41,
      "width" : 892,
      "height" : 460
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 67153, 67154, 67155, 67156, 67157, 67158, 67159, 67160, 67161, 67163, 67164, 67162, 67165, 67166, 67167, 67168, 67169, 67170, 67171, 67172, 67173, 67174, 67175, 67176, 67177, 67178, 67179, 67180, 67181, 67188, 67189, 67190 ]
  } ],
  "notes" : [ ],
  "links" : [ {
    "id" : 67189,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1545,
      "y" : 321
    },
    "minX" : 1539,
    "maxX" : 1551,
    "minY" : 315,
    "maxY" : 327,
    "segments" : [ {
      "from" : {
        "x" : 1539,
        "y" : 322
      },
      "to" : {
        "x" : 1551,
        "y" : 321
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1539,
        "y" : 315
      },
      "b" : {
        "x" : 1551,
        "y" : 327
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1545,
        "y" : 321
      }
    },
    "inputs" : [ {
      "id" : 67167
    } ],
    "outputs" : [ {
      "id" : 67178
    } ]
  }, {
    "id" : 67188,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1519,
      "y" : 385
    },
    "minX" : 1470,
    "maxX" : 1569,
    "minY" : 347,
    "maxY" : 423,
    "segments" : [ {
      "from" : {
        "x" : 1470,
        "y" : 423
      },
      "to" : {
        "x" : 1569,
        "y" : 347
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1513,
        "y" : 379
      },
      "b" : {
        "x" : 1525,
        "y" : 391
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1519,
        "y" : 385
      }
    },
    "inputs" : [ {
      "id" : 67173
    } ],
    "outputs" : [ {
      "id" : 67178
    } ]
  }, {
    "id" : 67190,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1547,
      "y" : 258
    },
    "minX" : 1517,
    "maxX" : 1578,
    "minY" : 221,
    "maxY" : 295,
    "segments" : [ {
      "from" : {
        "x" : 1517,
        "y" : 221
      },
      "to" : {
        "x" : 1578,
        "y" : 295
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1541,
        "y" : 252
      },
      "b" : {
        "x" : 1553,
        "y" : 264
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1547,
        "y" : 258
      }
    },
    "inputs" : [ {
      "id" : 67170
    } ],
    "outputs" : [ {
      "id" : 67178
    } ]
  } ],
  "shadows" : [ {
    "id" : 67191,
    "reactomeId" : 10223917,
    "displayName" : "HuR (ELAVL1) binds and stabilizes mRNA",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1373,
      "y" : 337
    },
    "minX" : 977,
    "maxX" : 1770,
    "minY" : 46,
    "maxY" : 628,
    "prop" : {
      "x" : 1217,
      "y" : 46,
      "width" : 553,
      "height" : 413
    },
    "points" : [ {
      "x" : 977,
      "y" : 46
    }, {
      "x" : 1770,
      "y" : 46
    }, {
      "x" : 1770,
      "y" : 628
    }, {
      "x" : 977,
      "y" : 628
    } ],
    "colour" : "#4684ee"
  }, {
    "id" : 67193,
    "reactomeId" : 10223923,
    "displayName" : "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 976,
      "y" : 662
    },
    "minX" : 526,
    "maxX" : 1427,
    "minY" : 498,
    "maxY" : 827,
    "prop" : {
      "x" : 526,
      "y" : 498,
      "width" : 901,
      "height" : 329
    },
    "points" : [ {
      "x" : 526,
      "y" : 498
    }, {
      "x" : 1427,
      "y" : 498
    }, {
      "x" : 1427,
      "y" : 827
    }, {
      "x" : 526,
      "y" : 827
    } ],
    "colour" : "#008000"
  }, {
    "id" : 67192,
    "reactomeId" : 10223921,
    "displayName" : "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 867,
      "y" : 683
    },
    "minX" : 313,
    "maxX" : 1422,
    "minY" : 459,
    "maxY" : 907,
    "prop" : {
      "x" : 313,
      "y" : 827,
      "width" : 1109,
      "height" : 80
    },
    "points" : [ {
      "x" : 313,
      "y" : 459
    }, {
      "x" : 1422,
      "y" : 459
    }, {
      "x" : 1422,
      "y" : 907
    }, {
      "x" : 313,
      "y" : 907
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 67195,
    "reactomeId" : 10223927,
    "displayName" : "AUF1 (hnRNP D0) binds and destabilizes mRNA",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 158,
      "y" : 313
    },
    "minX" : 19,
    "maxX" : 297,
    "minY" : 34,
    "maxY" : 592,
    "prop" : {
      "x" : 19,
      "y" : 35,
      "width" : 269,
      "height" : 557
    },
    "points" : [ {
      "x" : 19,
      "y" : 34
    }, {
      "x" : 297,
      "y" : 34
    }, {
      "x" : 297,
      "y" : 592
    }, {
      "x" : 19,
      "y" : 592
    } ],
    "colour" : "#4942cc"
  }, {
    "id" : 67194,
    "reactomeId" : 10223925,
    "displayName" : "KSRP (KHSRP) binds and destabilizes mRNA",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 752,
      "y" : 363
    },
    "minX" : 288,
    "maxX" : 1217,
    "minY" : 35,
    "maxY" : 692,
    "prop" : {
      "x" : 297,
      "y" : 46,
      "width" : 680,
      "height" : 413
    },
    "points" : [ {
      "x" : 288,
      "y" : 35
    }, {
      "x" : 1217,
      "y" : 35
    }, {
      "x" : 1217,
      "y" : 692
    }, {
      "x" : 288,
      "y" : 692
    } ],
    "colour" : "#666666"
  } ],
  "minX" : 0,
  "maxX" : 1896,
  "minY" : 0,
  "maxY" : 954,
  "disease" : false
}