{ "dbId" : 10223455, "stableId" : "R-RNO-264876", "displayName" : "Insulin processing", "nodes" : [ { "id" : 33153, "reactomeId" : 167012, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 450, "y" : 257 }, "minX" : 419, "maxX" : 522, "minY" : 240, "maxY" : 274, "prop" : { "x" : 419, "y" : 241, "width" : 63, "height" : 33 }, "textPosition" : { "x" : 429, "y" : 247 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 477, "y" : 246 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 477, "y" : 246 } } }, "connectors" : [ { "edgeId" : 33152, "type" : "INPUT", "segments" : [ { "from" : { "x" : 485, "y" : 257 }, "to" : { "x" : 522, "y" : 258 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33154, "reactomeId" : 216667, "displayName" : "Zn2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 495, "y" : 201 }, "minX" : 466, "maxX" : 526, "minY" : 170, "maxY" : 258, "prop" : { "x" : 466, "y" : 186, "width" : 59, "height" : 30 }, "textPosition" : { "x" : 474, "y" : 190 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 520, "y" : 191 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 520, "y" : 191 } } }, "connectors" : [ { "edgeId" : 33152, "type" : "INPUT", "segments" : [ { "from" : { "x" : 502, "y" : 219 }, "to" : { "x" : 522, "y" : 258 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 506, "y" : 232 }, "b" : { "x" : 518, "y" : 244 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 512, "y" : 238 } } } }, { "edgeId" : 33185, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 33174, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 489, "y" : 183 }, "to" : { "x" : 484, "y" : 170 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 483, "y" : 178 }, "b" : { "x" : 489, "y" : 183 }, "c" : { "x" : 490, "y" : 175 }, "type" : "ARROW", "centre" : { "x" : 490, "y" : 175 } } } ] }, { "id" : 33155, "reactomeId" : 10129028, "displayName" : "6xProinsulin:2xZn2+:1xCa2+", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 666, "y" : 260 }, "minX" : 590, "maxX" : 749, "minY" : 235, "maxY" : 280, "prop" : { "x" : 590, "y" : 241, "width" : 153, "height" : 39 }, "textPosition" : { "x" : 596, "y" : 245 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 743, "y" : 241 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 743, "y" : 241 } } }, "connectors" : [ { "edgeId" : 33152, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 33156, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33157, "reactomeId" : 10129058, "displayName" : "6xProinsulin:2xZn2+:1xCa2+", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 992, "y" : 172 }, "minX" : 882, "maxX" : 1108, "minY" : 154, "maxY" : 185, "prop" : { "x" : 882, "y" : 160, "width" : 220, "height" : 25 }, "textPosition" : { "x" : 898, "y" : 164 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1102, "y" : 160 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1102, "y" : 160 } } }, "connectors" : [ { "edgeId" : 33156, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33159, "reactomeId" : 10129088, "displayName" : "Exoc8", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1575, "y" : 18 }, "minX" : 1549, "maxX" : 1733, "minY" : 0, "maxY" : 155, "prop" : { "x" : 1549, "y" : 6, "width" : 53, "height" : 25 }, "textPosition" : { "x" : 1553, "y" : 8 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1602, "y" : 6 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1602, "y" : 6 } } }, "connectors" : [ { "edgeId" : 33158, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1589, "y" : 34 }, "to" : { "x" : 1733, "y" : 155 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33160, "reactomeId" : 10129099, "displayName" : "Exoc3", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1605, "y" : 196 }, "minX" : 1581, "maxX" : 1733, "minY" : 155, "maxY" : 207, "prop" : { "x" : 1581, "y" : 185, "width" : 49, "height" : 22 }, "textPosition" : { "x" : 1583, "y" : 185 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1630, "y" : 185 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1630, "y" : 185 } } }, "connectors" : [ { "edgeId" : 33158, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1633, "y" : 188 }, "to" : { "x" : 1733, "y" : 155 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33161, "reactomeId" : 10129064, "displayName" : "Exoc4", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1868, "y" : 60 }, "minX" : 1733, "maxX" : 1903, "minY" : 43, "maxY" : 155, "prop" : { "x" : 1840, "y" : 49, "width" : 57, "height" : 23 }, "textPosition" : { "x" : 1846, "y" : 50 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1897, "y" : 49 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1897, "y" : 49 } } }, "connectors" : [ { "edgeId" : 33158, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1851, "y" : 75 }, "to" : { "x" : 1733, "y" : 155 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33162, "reactomeId" : 10129105, "displayName" : "Exoc7", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1648, "y" : 17 }, "minX" : 1624, "maxX" : 1733, "minY" : 0, "maxY" : 155, "prop" : { "x" : 1624, "y" : 6, "width" : 49, "height" : 22 }, "textPosition" : { "x" : 1626, "y" : 6 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1673, "y" : 6 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1673, "y" : 6 } } }, "connectors" : [ { "edgeId" : 33158, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1654, "y" : 31 }, "to" : { "x" : 1733, "y" : 155 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33163, "reactomeId" : 10129092, "displayName" : "Exoc1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1502, "y" : 17 }, "minX" : 1478, "maxX" : 1733, "minY" : 0, "maxY" : 155, "prop" : { "x" : 1478, "y" : 6, "width" : 49, "height" : 22 }, "textPosition" : { "x" : 1480, "y" : 6 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1527, "y" : 6 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1527, "y" : 6 } } }, "connectors" : [ { "edgeId" : 33158, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1520, "y" : 31 }, "to" : { "x" : 1733, "y" : 155 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33164, "reactomeId" : 10129076, "displayName" : "Exoc5", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1652, "y" : 144 }, "minX" : 1624, "maxX" : 1733, "minY" : 128, "maxY" : 155, "prop" : { "x" : 1624, "y" : 134, "width" : 57, "height" : 21 }, "textPosition" : { "x" : 1630, "y" : 134 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1681, "y" : 134 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1681, "y" : 134 } } }, "connectors" : [ { "edgeId" : 33158, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1684, "y" : 147 }, "to" : { "x" : 1733, "y" : 155 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33165, "reactomeId" : 10129080, "displayName" : "Exoc6", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1722, "y" : 18 }, "minX" : 1694, "maxX" : 1757, "minY" : 0, "maxY" : 155, "prop" : { "x" : 1694, "y" : 6, "width" : 57, "height" : 25 }, "textPosition" : { "x" : 1700, "y" : 8 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1751, "y" : 6 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1751, "y" : 6 } } }, "connectors" : [ { "edgeId" : 33158, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1723, "y" : 34 }, "to" : { "x" : 1733, "y" : 155 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33166, "reactomeId" : 10129069, "displayName" : "Exoc2", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1805, "y" : 18 }, "minX" : 1733, "maxX" : 1840, "minY" : 0, "maxY" : 155, "prop" : { "x" : 1776, "y" : 6, "width" : 58, "height" : 24 }, "textPosition" : { "x" : 1782, "y" : 7 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1834, "y" : 6 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1834, "y" : 6 } } }, "connectors" : [ { "edgeId" : 33158, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1798, "y" : 33 }, "to" : { "x" : 1733, "y" : 155 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33167, "reactomeId" : 10129107, "displayName" : "Exocyst Complex", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1737, "y" : 262 }, "minX" : 1581, "maxX" : 1899, "minY" : 244, "maxY" : 274, "prop" : { "x" : 1581, "y" : 250, "width" : 312, "height" : 24 }, "textPosition" : { "x" : 1681, "y" : 253 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1893, "y" : 250 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1893, "y" : 250 } } }, "connectors" : [ { "edgeId" : 33158, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33169, "reactomeId" : 29426, "displayName" : "Zn2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1333, "y" : 103 }, "minX" : 1309, "maxX" : 1359, "minY" : 87, "maxY" : 130, "prop" : { "x" : 1309, "y" : 88, "width" : 49, "height" : 30 }, "textPosition" : { "x" : 1312, "y" : 92 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1353, "y" : 93 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1353, "y" : 93 } } }, "connectors" : [ { "edgeId" : 33168, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1335, "y" : 121 }, "to" : { "x" : 1337, "y" : 130 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 33179, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33170, "reactomeId" : 5339575, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1412, "y" : 197 }, "minX" : 1337, "maxX" : 1429, "minY" : 130, "maxY" : 213, "prop" : { "x" : 1396, "y" : 182, "width" : 32, "height" : 31 }, "textPosition" : { "x" : 1398, "y" : 187 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1423, "y" : 187 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1423, "y" : 187 } } }, "connectors" : [ { "edgeId" : 33168, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1393, "y" : 182 }, "to" : { "x" : 1337, "y" : 130 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 1359, "y" : 150 }, "b" : { "x" : 1371, "y" : 162 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1365, "y" : 156 } } } } ], "trivial" : true }, { "id" : 33171, "reactomeId" : 216785, "displayName" : "Zn2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1330, "y" : 190 }, "minX" : 1306, "maxX" : 1356, "minY" : 156, "maxY" : 205, "prop" : { "x" : 1306, "y" : 175, "width" : 49, "height" : 30 }, "textPosition" : { "x" : 1309, "y" : 179 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1350, "y" : 180 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1350, "y" : 180 } } }, "connectors" : [ { "edgeId" : 33168, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1332, "y" : 172 }, "to" : { "x" : 1336, "y" : 156 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1330, "y" : 164 }, "b" : { "x" : 1332, "y" : 172 }, "c" : { "x" : 1338, "y" : 166 }, "type" : "ARROW", "centre" : { "x" : 1338, "y" : 166 } } }, { "edgeId" : 33179, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33172, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1408, "y" : 88 }, "minX" : 1336, "maxX" : 1424, "minY" : 74, "maxY" : 156, "prop" : { "x" : 1393, "y" : 75, "width" : 30, "height" : 27 }, "textPosition" : { "x" : 1394, "y" : 78 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1418, "y" : 80 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1418, "y" : 80 } } }, "connectors" : [ { "edgeId" : 33168, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1393, "y" : 105 }, "to" : { "x" : 1336, "y" : 156 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 1358, "y" : 124 }, "b" : { "x" : 1370, "y" : 136 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1364, "y" : 130 } } }, "endShape" : { "a" : { "x" : 1391, "y" : 113 }, "b" : { "x" : 1393, "y" : 105 }, "c" : { "x" : 1385, "y" : 107 }, "type" : "ARROW", "centre" : { "x" : 1385, "y" : 107 } } } ], "trivial" : true }, { "id" : 33173, "reactomeId" : 10139782, "displayName" : "SLC30A8", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1416, "y" : 146 }, "minX" : 1348, "maxX" : 1463, "minY" : 129, "maxY" : 157, "prop" : { "x" : 1375, "y" : 135, "width" : 82, "height" : 22 }, "textPosition" : { "x" : 1385, "y" : 135 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1457, "y" : 135 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1457, "y" : 135 } } }, "connectors" : [ { "edgeId" : 33168, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1372, "y" : 142 }, "to" : { "x" : 1356, "y" : 141 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1352, "y" : 141 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1352, "y" : 141 } } } ] }, { "id" : 33175, "reactomeId" : 425969, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 437, "y" : 214 }, "minX" : 423, "maxX" : 484, "minY" : 144, "maxY" : 228, "prop" : { "x" : 423, "y" : 201, "width" : 28, "height" : 27 }, "textPosition" : { "x" : 423, "y" : 204 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 446, "y" : 206 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 446, "y" : 206 } } }, "connectors" : [ { "edgeId" : 33174, "type" : "INPUT", "segments" : [ { "from" : { "x" : 446, "y" : 198 }, "to" : { "x" : 484, "y" : 144 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 459, "y" : 165 }, "b" : { "x" : 471, "y" : 177 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 465, "y" : 171 } } } } ], "trivial" : true }, { "id" : 33176, "reactomeId" : 29426, "displayName" : "Zn2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 495, "y" : 112 }, "minX" : 471, "maxX" : 521, "minY" : 96, "maxY" : 144, "prop" : { "x" : 471, "y" : 97, "width" : 49, "height" : 30 }, "textPosition" : { "x" : 474, "y" : 101 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 515, "y" : 102 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 515, "y" : 102 } } }, "connectors" : [ { "edgeId" : 33185, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 33174, "type" : "INPUT", "segments" : [ { "from" : { "x" : 489, "y" : 130 }, "to" : { "x" : 484, "y" : 144 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33177, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 429, "y" : 93 }, "minX" : 414, "maxX" : 484, "minY" : 79, "maxY" : 170, "prop" : { "x" : 414, "y" : 80, "width" : 30, "height" : 27 }, "textPosition" : { "x" : 415, "y" : 83 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 439, "y" : 85 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 439, "y" : 85 } } }, "connectors" : [ { "edgeId" : 33174, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 438, "y" : 110 }, "to" : { "x" : 484, "y" : 170 } } ], "stoichiometry" : { "value" : 2, "shape" : { "a" : { "x" : 455, "y" : 134 }, "b" : { "x" : 467, "y" : 146 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 461, "y" : 140 } } }, "endShape" : { "a" : { "x" : 445, "y" : 113 }, "b" : { "x" : 438, "y" : 110 }, "c" : { "x" : 439, "y" : 118 }, "type" : "ARROW", "centre" : { "x" : 439, "y" : 118 } } } ], "trivial" : true }, { "id" : 33178, "reactomeId" : 10139789, "displayName" : "SLC30A8 dimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 409, "y" : 158 }, "minX" : 373, "maxX" : 471, "minY" : 135, "maxY" : 176, "prop" : { "x" : 373, "y" : 141, "width" : 73, "height" : 35 }, "textPosition" : { "x" : 376, "y" : 141 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 446, "y" : 141 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 446, "y" : 141 } } }, "connectors" : [ { "edgeId" : 33174, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 449, "y" : 158 }, "to" : { "x" : 463, "y" : 158 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 467, "y" : 158 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 467, "y" : 158 } } } ] }, { "id" : 33180, "reactomeId" : 10139770, "displayName" : "Slc30a5", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1248, "y" : 141 }, "minX" : 1204, "maxX" : 1312, "minY" : 124, "maxY" : 153, "prop" : { "x" : 1204, "y" : 130, "width" : 88, "height" : 23 }, "textPosition" : { "x" : 1219, "y" : 131 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1292, "y" : 130 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1292, "y" : 130 } } }, "connectors" : [ { "edgeId" : 33179, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1295, "y" : 141 }, "to" : { "x" : 1304, "y" : 141 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1308, "y" : 141 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1308, "y" : 141 } } } ] }, { "id" : 33182, "reactomeId" : 113534, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 269, "y" : 326 }, "minX" : 214, "maxX" : 287, "minY" : 309, "maxY" : 342, "prop" : { "x" : 252, "y" : 311, "width" : 34, "height" : 31 }, "textPosition" : { "x" : 256, "y" : 316 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 281, "y" : 316 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 281, "y" : 316 } } }, "connectors" : [ { "edgeId" : 33181, "type" : "INPUT", "segments" : [ { "from" : { "x" : 249, "y" : 320 }, "to" : { "x" : 214, "y" : 309 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 33183, "reactomeId" : 3341383, "displayName" : "H2O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 269, "y" : 211 }, "minX" : 214, "maxX" : 296, "minY" : 195, "maxY" : 229, "prop" : { "x" : 244, "y" : 196, "width" : 51, "height" : 31 }, "textPosition" : { "x" : 248, "y" : 201 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 290, "y" : 201 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 290, "y" : 201 } } }, "connectors" : [ { "edgeId" : 33181, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 241, "y" : 219 }, "to" : { "x" : 214, "y" : 229 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 236, "y" : 225 }, "b" : { "x" : 241, "y" : 219 }, "c" : { "x" : 233, "y" : 218 }, "type" : "ARROW", "centre" : { "x" : 233, "y" : 218 } } } ] }, { "id" : 33184, "reactomeId" : 10216544, "displayName" : "ERO1B", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 269, "y" : 265 }, "minX" : 222, "maxX" : 299, "minY" : 248, "maxY" : 277, "prop" : { "x" : 245, "y" : 254, "width" : 48, "height" : 23 }, "textPosition" : { "x" : 248, "y" : 248 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 293, "y" : 254 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 293, "y" : 254 } } }, "connectors" : [ { "edgeId" : 33181, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 242, "y" : 264 }, "to" : { "x" : 230, "y" : 264 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 226, "y" : 264 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 226, "y" : 264 } } } ] }, { "id" : 33186, "reactomeId" : 10216598, "displayName" : "SLC30A5 dimer", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 576, "y" : 158 }, "minX" : 515, "maxX" : 612, "minY" : 135, "maxY" : 176, "prop" : { "x" : 546, "y" : 141, "width" : 60, "height" : 35 }, "textPosition" : { "x" : 548, "y" : 141 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 606, "y" : 141 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 606, "y" : 141 } } }, "connectors" : [ { "edgeId" : 33185, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 543, "y" : 157 }, "to" : { "x" : 523, "y" : 157 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 519, "y" : 157 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 519, "y" : 157 } } } ] }, { "id" : 33146, "reactomeId" : 10129036, "displayName" : "Homologues of INS(25-110)", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 113, "y" : 123 }, "minX" : 59, "maxX" : 167, "minY" : 108, "maxY" : 188, "prop" : { "x" : 59, "y" : 108, "width" : 108, "height" : 30 }, "textPosition" : { "x" : 60, "y" : 106 }, "connectors" : [ { "edgeId" : 33145, "type" : "INPUT", "segments" : [ { "from" : { "x" : 107, "y" : 141 }, "to" : { "x" : 88, "y" : 188 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33147, "reactomeId" : 10129039, "displayName" : "P4hb", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 185, "y" : 164 }, "minX" : 88, "maxX" : 241, "minY" : 147, "maxY" : 229, "prop" : { "x" : 135, "y" : 153, "width" : 100, "height" : 23 }, "textPosition" : { "x" : 165, "y" : 154 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 235, "y" : 153 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 235, "y" : 153 } } }, "connectors" : [ { "edgeId" : 33145, "type" : "INPUT", "segments" : [ { "from" : { "x" : 138, "y" : 179 }, "to" : { "x" : 88, "y" : 188 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 33145, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 172, "y" : 179 }, "to" : { "x" : 127, "y" : 218 } }, { "from" : { "x" : 127, "y" : 218 }, "to" : { "x" : 104, "y" : 219 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 100, "y" : 219 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 100, "y" : 219 } } }, { "edgeId" : 33181, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 190, "y" : 179 }, "to" : { "x" : 214, "y" : 229 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 197, "y" : 184 }, "b" : { "x" : 190, "y" : 179 }, "c" : { "x" : 189, "y" : 187 }, "type" : "ARROW", "centre" : { "x" : 189, "y" : 187 } } } ] }, { "id" : 33148, "reactomeId" : 10129045, "displayName" : "Homologues of 6xHC-INS(25-110)", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 131, "y" : 423 }, "minX" : 63, "maxX" : 200, "minY" : 302, "maxY" : 441, "prop" : { "x" : 63, "y" : 405, "width" : 137, "height" : 36 }, "textPosition" : { "x" : 73, "y" : 405 }, "connectors" : [ { "edgeId" : 33145, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 124, "y" : 402 }, "to" : { "x" : 89, "y" : 302 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 118, "y" : 397 }, "b" : { "x" : 124, "y" : 402 }, "c" : { "x" : 125, "y" : 394 }, "type" : "ARROW", "centre" : { "x" : 125, "y" : 394 } } }, { "edgeId" : 33150, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33149, "reactomeId" : 10119486, "displayName" : "P4hb", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 160, "y" : 343 }, "minX" : 89, "maxX" : 214, "minY" : 302, "maxY" : 355, "prop" : { "x" : 140, "y" : 332, "width" : 40, "height" : 23 }, "textPosition" : { "x" : 140, "y" : 333 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 180, "y" : 332 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 180, "y" : 332 } } }, "connectors" : [ { "edgeId" : 33145, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 140, "y" : 329 }, "to" : { "x" : 89, "y" : 302 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 132, "y" : 329 }, "b" : { "x" : 140, "y" : 329 }, "c" : { "x" : 136, "y" : 322 }, "type" : "ARROW", "centre" : { "x" : 136, "y" : 322 } } }, { "edgeId" : 33181, "type" : "INPUT", "segments" : [ { "from" : { "x" : 178, "y" : 329 }, "to" : { "x" : 214, "y" : 309 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 33151, "reactomeId" : 10129026, "displayName" : "Homologues of 6xHC-INS(25-110)", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 498, "y" : 351 }, "minX" : 433, "maxX" : 564, "minY" : 258, "maxY" : 370, "prop" : { "x" : 433, "y" : 333, "width" : 131, "height" : 37 }, "textPosition" : { "x" : 440, "y" : 334 }, "connectors" : [ { "edgeId" : 33152, "type" : "INPUT", "segments" : [ { "from" : { "x" : 502, "y" : 330 }, "to" : { "x" : 522, "y" : 258 } } ], "stoichiometry" : { "value" : 6, "shape" : { "a" : { "x" : 506, "y" : 288 }, "b" : { "x" : 518, "y" : 300 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 512, "y" : 294 } } } }, { "edgeId" : 33150, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] } ], "edges" : [ { "id" : 33168, "reactomeId" : 10139785, "displayName" : "SLC30A8 transports Zn2+ from cytosol to secretory granule", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1340, "y" : 140 }, "minX" : 1334, "maxX" : 1346, "minY" : 130, "maxY" : 156, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1337, "y" : 130 }, "to" : { "x" : 1340, "y" : 140 } }, { "from" : { "x" : 1340, "y" : 140 }, "to" : { "x" : 1336, "y" : 156 } } ], "reactionShape" : { "a" : { "x" : 1334, "y" : 134 }, "b" : { "x" : 1346, "y" : 146 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1340, "y" : 140 } }, "inputs" : [ { "id" : 33169, "points" : [ { "x" : 1335, "y" : 121 } ] }, { "id" : 33170, "points" : [ { "x" : 1393, "y" : 182 } ], "stoichiometry" : 2 } ], "outputs" : [ { "id" : 33171, "points" : [ { "x" : 1332, "y" : 172 } ] }, { "id" : 33172, "points" : [ { "x" : 1393, "y" : 105 } ], "stoichiometry" : 2 } ], "catalysts" : [ { "id" : 33173, "points" : [ { "x" : 1372, "y" : 142 } ] } ] }, { "id" : 33152, "reactomeId" : 10129030, "displayName" : "Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 544, "y" : 258 }, "minX" : 522, "maxX" : 587, "minY" : 252, "maxY" : 264, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 522, "y" : 258 }, "to" : { "x" : 544, "y" : 258 } }, { "from" : { "x" : 544, "y" : 258 }, "to" : { "x" : 587, "y" : 258 } } ], "endShape" : { "a" : { "x" : 580, "y" : 262 }, "b" : { "x" : 587, "y" : 258 }, "c" : { "x" : 580, "y" : 254 }, "type" : "ARROW", "centre" : { "x" : 580, "y" : 254 } }, "reactionShape" : { "c" : { "x" : 544, "y" : 258 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 544, "y" : 258 } }, "inputs" : [ { "id" : 33153, "points" : [ { "x" : 485, "y" : 257 } ] }, { "id" : 33154, "points" : [ { "x" : 502, "y" : 219 } ], "stoichiometry" : 2 }, { "id" : 33151, "points" : [ { "x" : 502, "y" : 330 } ], "stoichiometry" : 6 } ], "outputs" : [ { "id" : 33155 } ] }, { "id" : 33185, "reactomeId" : 10216601, "displayName" : "ZnT5 transports zinc into the golgi apparatus", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 507, "y" : 157 }, "minX" : 499, "maxX" : 513, "minY" : 130, "maxY" : 183, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 499, "y" : 130 }, "to" : { "x" : 507, "y" : 157 } }, { "from" : { "x" : 507, "y" : 157 }, "to" : { "x" : 499, "y" : 183 } } ], "endShape" : { "a" : { "x" : 497, "y" : 175 }, "b" : { "x" : 499, "y" : 183 }, "c" : { "x" : 505, "y" : 178 }, "type" : "ARROW", "centre" : { "x" : 505, "y" : 178 } }, "reactionShape" : { "a" : { "x" : 501, "y" : 151 }, "b" : { "x" : 513, "y" : 163 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 507, "y" : 157 } }, "inputs" : [ { "id" : 33176 } ], "outputs" : [ { "id" : 33154 } ], "catalysts" : [ { "id" : 33186, "points" : [ { "x" : 543, "y" : 157 } ] } ] }, { "id" : 33156, "reactomeId" : 10129060, "displayName" : "Proinsulin:Zinc:Calcium complex translocates to immature secretory granule", "schemaClass" : "BlackBoxEvent", "renderableClass" : "Reaction", "position" : { "x" : 797, "y" : 233 }, "minX" : 746, "maxX" : 952, "minY" : 188, "maxY" : 244, "reactionType" : "omitted", "segments" : [ { "from" : { "x" : 746, "y" : 244 }, "to" : { "x" : 797, "y" : 233 } }, { "from" : { "x" : 797, "y" : 233 }, "to" : { "x" : 952, "y" : 188 } } ], "endShape" : { "a" : { "x" : 946, "y" : 194 }, "b" : { "x" : 952, "y" : 188 }, "c" : { "x" : 944, "y" : 186 }, "type" : "ARROW", "centre" : { "x" : 944, "y" : 186 } }, "reactionShape" : { "a" : { "x" : 791, "y" : 227 }, "b" : { "x" : 803, "y" : 239 }, "s" : "\\\\", "type" : "BOX", "empty" : true, "centre" : { "x" : 797, "y" : 233 } }, "inputs" : [ { "id" : 33155 } ], "outputs" : [ { "id" : 33157 } ] }, { "id" : 33174, "reactomeId" : 10139792, "displayName" : "ZnT8 transports zinc into the Golgi apparatus", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 479, "y" : 158 }, "minX" : 473, "maxX" : 485, "minY" : 144, "maxY" : 170, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 484, "y" : 144 }, "to" : { "x" : 479, "y" : 158 } }, { "from" : { "x" : 479, "y" : 158 }, "to" : { "x" : 484, "y" : 170 } } ], "reactionShape" : { "a" : { "x" : 473, "y" : 152 }, "b" : { "x" : 485, "y" : 164 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 479, "y" : 158 } }, "inputs" : [ { "id" : 33175, "points" : [ { "x" : 446, "y" : 198 } ], "stoichiometry" : 2 }, { "id" : 33176, "points" : [ { "x" : 489, "y" : 130 } ] } ], "outputs" : [ { "id" : 33177, "points" : [ { "x" : 438, "y" : 110 } ], "stoichiometry" : 2 }, { "id" : 33154, "points" : [ { "x" : 489, "y" : 183 } ] } ], "catalysts" : [ { "id" : 33178, "points" : [ { "x" : 449, "y" : 158 } ] } ] }, { "id" : 33158, "reactomeId" : 10129109, "displayName" : "Exocyst complex formation", "schemaClass" : "BlackBoxEvent", "renderableClass" : "Reaction", "position" : { "x" : 1734, "y" : 199 }, "minX" : 1728, "maxX" : 1740, "minY" : 155, "maxY" : 247, "reactionType" : "omitted", "segments" : [ { "from" : { "x" : 1733, "y" : 155 }, "to" : { "x" : 1734, "y" : 199 } }, { "from" : { "x" : 1734, "y" : 199 }, "to" : { "x" : 1736, "y" : 247 } } ], "endShape" : { "a" : { "x" : 1732, "y" : 240 }, "b" : { "x" : 1736, "y" : 247 }, "c" : { "x" : 1740, "y" : 240 }, "type" : "ARROW", "centre" : { "x" : 1740, "y" : 240 } }, "reactionShape" : { "a" : { "x" : 1728, "y" : 193 }, "b" : { "x" : 1740, "y" : 205 }, "s" : "\\\\", "type" : "BOX", "empty" : true, "centre" : { "x" : 1734, "y" : 199 } }, "inputs" : [ { "id" : 33159, "points" : [ { "x" : 1589, "y" : 34 } ] }, { "id" : 33160, "points" : [ { "x" : 1633, "y" : 188 } ] }, { "id" : 33161, "points" : [ { "x" : 1851, "y" : 75 } ] }, { "id" : 33162, "points" : [ { "x" : 1654, "y" : 31 } ] }, { "id" : 33163, "points" : [ { "x" : 1520, "y" : 31 } ] }, { "id" : 33164, "points" : [ { "x" : 1684, "y" : 147 } ] }, { "id" : 33165, "points" : [ { "x" : 1723, "y" : 34 } ] }, { "id" : 33166, "points" : [ { "x" : 1798, "y" : 33 } ] } ], "outputs" : [ { "id" : 33167 } ] }, { "id" : 33145, "reactomeId" : 10129048, "displayName" : "P4HB mediates disulfide bond formation in Proinsulin", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 88, "y" : 219 }, "minX" : 82, "maxX" : 94, "minY" : 188, "maxY" : 302, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 88, "y" : 188 }, "to" : { "x" : 88, "y" : 219 } }, { "from" : { "x" : 88, "y" : 219 }, "to" : { "x" : 89, "y" : 302 } } ], "reactionShape" : { "a" : { "x" : 82, "y" : 213 }, "b" : { "x" : 94, "y" : 225 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 88, "y" : 219 } }, "inputs" : [ { "id" : 33146, "points" : [ { "x" : 107, "y" : 141 } ] }, { "id" : 33147, "points" : [ { "x" : 138, "y" : 179 } ] } ], "outputs" : [ { "id" : 33148, "points" : [ { "x" : 124, "y" : 402 } ] }, { "id" : 33149, "points" : [ { "x" : 140, "y" : 329 } ] } ], "catalysts" : [ { "id" : 33147, "points" : [ { "x" : 172, "y" : 179 }, { "x" : 127, "y" : 218 } ] } ] }, { "id" : 33179, "reactomeId" : 10139773, "displayName" : "ZnT5 transports zinc into secretory granules in pancreatic beta cells", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1320, "y" : 141 }, "minX" : 1314, "maxX" : 1327, "minY" : 121, "maxY" : 172, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1327, "y" : 121 }, "to" : { "x" : 1320, "y" : 141 } }, { "from" : { "x" : 1320, "y" : 141 }, "to" : { "x" : 1326, "y" : 172 } } ], "endShape" : { "a" : { "x" : 1321, "y" : 166 }, "b" : { "x" : 1326, "y" : 172 }, "c" : { "x" : 1329, "y" : 164 }, "type" : "ARROW", "centre" : { "x" : 1329, "y" : 164 } }, "reactionShape" : { "a" : { "x" : 1314, "y" : 135 }, "b" : { "x" : 1326, "y" : 147 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1320, "y" : 141 } }, "inputs" : [ { "id" : 33169 } ], "outputs" : [ { "id" : 33171 } ], "catalysts" : [ { "id" : 33180, "points" : [ { "x" : 1295, "y" : 141 } ] } ] }, { "id" : 33181, "reactomeId" : 10216547, "displayName" : "ERO1B oxidizes P4HB", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 214, "y" : 264 }, "minX" : 208, "maxX" : 220, "minY" : 229, "maxY" : 309, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 214, "y" : 309 }, "to" : { "x" : 214, "y" : 264 } }, { "from" : { "x" : 214, "y" : 264 }, "to" : { "x" : 214, "y" : 229 } } ], "reactionShape" : { "a" : { "x" : 208, "y" : 258 }, "b" : { "x" : 220, "y" : 270 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 214, "y" : 264 } }, "inputs" : [ { "id" : 33182, "points" : [ { "x" : 249, "y" : 320 } ] }, { "id" : 33149, "points" : [ { "x" : 178, "y" : 329 } ] } ], "outputs" : [ { "id" : 33147, "points" : [ { "x" : 190, "y" : 179 } ] }, { "id" : 33183, "points" : [ { "x" : 241, "y" : 219 } ] } ], "catalysts" : [ { "id" : 33184, "points" : [ { "x" : 242, "y" : 264 } ] } ] }, { "id" : 33150, "reactomeId" : 10129050, "displayName" : "Proinsulin translocates from the endoplasmic reticulum to the Golgi", "schemaClass" : "BlackBoxEvent", "renderableClass" : "Reaction", "position" : { "x" : 374, "y" : 425 }, "minX" : 203, "maxX" : 467, "minY" : 373, "maxY" : 431, "reactionType" : "omitted", "segments" : [ { "from" : { "x" : 203, "y" : 423 }, "to" : { "x" : 374, "y" : 425 } }, { "from" : { "x" : 374, "y" : 425 }, "to" : { "x" : 467, "y" : 373 } } ], "endShape" : { "a" : { "x" : 463, "y" : 380 }, "b" : { "x" : 467, "y" : 373 }, "c" : { "x" : 459, "y" : 373 }, "type" : "ARROW", "centre" : { "x" : 459, "y" : 373 } }, "reactionShape" : { "a" : { "x" : 368, "y" : 419 }, "b" : { "x" : 380, "y" : 431 }, "s" : "\\\\", "type" : "BOX", "empty" : true, "centre" : { "x" : 374, "y" : 425 } }, "inputs" : [ { "id" : 33148 } ], "outputs" : [ { "id" : 33151 } ] } ], "compartments" : [ { "id" : 33187, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 936, "y" : 405 }, "minX" : 0, "maxX" : 1872, "minY" : 6, "maxY" : 804, "prop" : { "x" : 0, "y" : 6, "width" : 1872, "height" : 798 }, "textPosition" : { "x" : 107, "y" : 736 }, "insets" : { "x" : 10, "y" : 16, "width" : 1852, "height" : 778 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 33188, 33189, 33190, 33164, 33159, 33165, 33162, 33163, 33169, 33176, 33156, 33166, 33161, 33158, 33150, 33177, 33172 ] }, { "id" : 33188, "reactomeId" : 17957, "displayName" : "endoplasmic reticulum lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 195, "y" : 318 }, "minX" : 39, "maxX" : 351, "minY" : 83, "maxY" : 553, "prop" : { "x" : 39, "y" : 83, "width" : 312, "height" : 470 }, "textPosition" : { "x" : 54, "y" : 504 }, "insets" : { "x" : 49, "y" : 93, "width" : 292, "height" : 450 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 33146, 33145, 33148, 33147, 33149, 33181, 33182, 33183, 33184 ] }, { "id" : 33189, "reactomeId" : 17963, "displayName" : "Golgi lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 593, "y" : 273 }, "minX" : 401, "maxX" : 785, "minY" : 152, "maxY" : 395, "prop" : { "x" : 401, "y" : 152, "width" : 384, "height" : 243 }, "textPosition" : { "x" : 674, "y" : 344 }, "insets" : { "x" : 411, "y" : 162, "width" : 364, "height" : 223 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 33155, 33152, 33153, 33154, 33174, 33151, 33178, 33186, 33185, 33175 ] }, { "id" : 33190, "reactomeId" : 216798, "displayName" : "secretory granule", "schemaClass" : "GO_CellularComponent", "renderableClass" : "Compartment", "position" : { "x" : 1213, "y" : 428 }, "minX" : 819, "maxX" : 1608, "minY" : 137, "maxY" : 719, "prop" : { "x" : 819, "y" : 137, "width" : 789, "height" : 582 }, "textPosition" : { "x" : 833, "y" : 663 }, "insets" : { "x" : 829, "y" : 147, "width" : 769, "height" : 562 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 33167, 33157, 33173, 33180, 33179, 33171, 33168, 33160, 33170 ] } ], "notes" : [ ], "links" : [ ], "shadows" : [ ], "minX" : 0, "maxX" : 1903, "minY" : 0, "maxY" : 804, "disease" : false }