{
  "dbId" : 10222865,
  "stableId" : "R-RNO-168928",
  "displayName" : "DDX58/IFIH1-mediated induction of interferon-alpha/beta",
  "nodes" : [ {
    "id" : 3077,
    "reactomeId" : 10116961,
    "displayName" : "phospho-Irf7",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2866,
      "y" : 531
    },
    "minX" : 2728,
    "maxX" : 2932,
    "minY" : 514,
    "maxY" : 543,
    "prop" : {
      "x" : 2806,
      "y" : 520,
      "width" : 120,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2822,
      "y" : 521
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2926,
          "y" : 520
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2926,
          "y" : 520
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3076,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 2728,
            "y" : 525
          },
          "b" : {
            "x" : 2740,
            "y" : 537
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2734,
            "y" : 531
          }
        }
      }
    } ]
  }, {
    "id" : 3078,
    "reactomeId" : 10117514,
    "displayName" : "p-2S-IRF7:p-2S-IRF7",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2489,
      "y" : 531
    },
    "minX" : 2156,
    "maxX" : 2550,
    "minY" : 433,
    "maxY" : 550,
    "prop" : {
      "x" : 2434,
      "y" : 513,
      "width" : 110,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2438,
      "y" : 515
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2544,
          "y" : 513
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2544,
          "y" : 513
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3076,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 3079,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 3112,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2431,
          "y" : 522
        },
        "to" : {
          "x" : 2156,
          "y" : 482
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2424,
          "y" : 525
        },
        "b" : {
          "x" : 2431,
          "y" : 522
        },
        "c" : {
          "x" : 2425,
          "y" : 517
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2425,
          "y" : 517
        }
      }
    }, {
      "edgeId" : 3116,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2481,
          "y" : 510
        },
        "to" : {
          "x" : 2448,
          "y" : 433
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3143,
    "reactomeId" : 10116946,
    "displayName" : "Irf7",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2742,
      "y" : 674
    },
    "minX" : 2725,
    "maxX" : 2765,
    "minY" : 657,
    "maxY" : 686,
    "prop" : {
      "x" : 2725,
      "y" : 663,
      "width" : 34,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2728,
      "y" : 664
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2759,
          "y" : 663
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2759,
          "y" : 663
        }
      }
    },
    "connectors" : [ ]
  }, {
    "id" : 3080,
    "reactomeId" : 10120170,
    "displayName" : "2xp-S477,S479-IRF7",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2601,
      "y" : 359
    },
    "minX" : 2481,
    "maxX" : 2683,
    "minY" : 335,
    "maxY" : 383,
    "prop" : {
      "x" : 2546,
      "y" : 341,
      "width" : 110,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2548,
      "y" : 343
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2656,
          "y" : 341
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2656,
          "y" : 341
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3079,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 3081,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2659,
          "y" : 359
        },
        "to" : {
          "x" : 2683,
          "y" : 359
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 3116,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2543,
          "y" : 370
        },
        "to" : {
          "x" : 2481,
          "y" : 383
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2537,
          "y" : 375
        },
        "b" : {
          "x" : 2543,
          "y" : 370
        },
        "c" : {
          "x" : 2535,
          "y" : 368
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2535,
          "y" : 368
        }
      }
    } ]
  }, {
    "id" : 3082,
    "reactomeId" : 10145960,
    "displayName" : "CREBBP,EP300",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2379,
      "y" : 314
    },
    "minX" : 2332,
    "maxX" : 2683,
    "minY" : 285,
    "maxY" : 359,
    "prop" : {
      "x" : 2332,
      "y" : 303,
      "width" : 95,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2349,
      "y" : 297
    },
    "connectors" : [ {
      "edgeId" : 3081,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2433,
          "y" : 313
        },
        "to" : {
          "x" : 2600,
          "y" : 313
        }
      }, {
        "from" : {
          "x" : 2600,
          "y" : 313
        },
        "to" : {
          "x" : 2683,
          "y" : 359
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 3119,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2433,
          "y" : 303
        },
        "to" : {
          "x" : 2509,
          "y" : 285
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3083,
    "reactomeId" : 10145962,
    "displayName" : "CBP/p300:pIRF7:pIRF7",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2770,
      "y" : 359
    },
    "minX" : 2715,
    "maxX" : 2831,
    "minY" : 335,
    "maxY" : 378,
    "prop" : {
      "x" : 2715,
      "y" : 341,
      "width" : 110,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2715,
      "y" : 343
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2825,
          "y" : 341
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2825,
          "y" : 341
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3081,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3085,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3250,
      "y" : 468
    },
    "minX" : 3210,
    "maxX" : 3271,
    "minY" : 452,
    "maxY" : 519,
    "prop" : {
      "x" : 3230,
      "y" : 453,
      "width" : 40,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3234,
      "y" : 458
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3265,
          "y" : 458
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3265,
          "y" : 458
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3084,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3237,
          "y" : 487
        },
        "to" : {
          "x" : 3210,
          "y" : 519
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 3217,
            "y" : 497
          },
          "b" : {
            "x" : 3229,
            "y" : 509
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 3223,
            "y" : 503
          }
        }
      }
    } ]
  }, {
    "id" : 3086,
    "reactomeId" : 10117243,
    "displayName" : "NFkB inhibitor:NFkB complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3305,
      "y" : 553
    },
    "minX" : 3210,
    "maxX" : 3374,
    "minY" : 519,
    "maxY" : 572,
    "prop" : {
      "x" : 3242,
      "y" : 535,
      "width" : 126,
      "height" : 37
    },
    "textPosition" : {
      "x" : 3256,
      "y" : 537
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3368,
          "y" : 535
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3368,
          "y" : 535
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3084,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3253,
          "y" : 532
        },
        "to" : {
          "x" : 3210,
          "y" : 519
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3087,
    "reactomeId" : 10117253,
    "displayName" : "Phospho-NF-kappaB Inhibitor",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 3110,
      "y" : 565
    },
    "minX" : 3043,
    "maxX" : 3178,
    "minY" : 519,
    "maxY" : 584,
    "prop" : {
      "x" : 3043,
      "y" : 547,
      "width" : 135,
      "height" : 37
    },
    "textPosition" : {
      "x" : 3042,
      "y" : 548
    },
    "connectors" : [ {
      "edgeId" : 3084,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3126,
          "y" : 541
        },
        "to" : {
          "x" : 3150,
          "y" : 519
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3128,
          "y" : 533
        },
        "b" : {
          "x" : 3126,
          "y" : 541
        },
        "c" : {
          "x" : 3134,
          "y" : 539
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3134,
          "y" : 539
        }
      }
    } ]
  }, {
    "id" : 3088,
    "reactomeId" : 10117228,
    "displayName" : "NFKB1(1-433), NFKB2(1-454):RELA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3038,
      "y" : 515
    },
    "minX" : 2975,
    "maxX" : 3150,
    "minY" : 491,
    "maxY" : 534,
    "prop" : {
      "x" : 2975,
      "y" : 497,
      "width" : 127,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2975,
      "y" : 499
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3102,
          "y" : 497
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3102,
          "y" : 497
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3109,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 3084,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3105,
          "y" : 517
        },
        "to" : {
          "x" : 3150,
          "y" : 519
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3112,
          "y" : 513
        },
        "b" : {
          "x" : 3105,
          "y" : 517
        },
        "c" : {
          "x" : 3112,
          "y" : 521
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3112,
          "y" : 521
        }
      }
    } ]
  }, {
    "id" : 3089,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3113,
      "y" : 465
    },
    "minX" : 3093,
    "maxX" : 3150,
    "minY" : 449,
    "maxY" : 519,
    "prop" : {
      "x" : 3093,
      "y" : 450,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 3097,
      "y" : 455
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3129,
          "y" : 455
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3129,
          "y" : 455
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3084,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3123,
          "y" : 484
        },
        "to" : {
          "x" : 3150,
          "y" : 519
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 3130,
            "y" : 495
          },
          "b" : {
            "x" : 3142,
            "y" : 507
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 3136,
            "y" : 501
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 3130,
          "y" : 487
        },
        "b" : {
          "x" : 3123,
          "y" : 484
        },
        "c" : {
          "x" : 3124,
          "y" : 492
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3124,
          "y" : 492
        }
      }
    } ]
  }, {
    "id" : 3090,
    "reactomeId" : 10117274,
    "displayName" : "IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3235,
      "y" : 624
    },
    "minX" : 3179,
    "maxX" : 3298,
    "minY" : 526,
    "maxY" : 650,
    "prop" : {
      "x" : 3179,
      "y" : 599,
      "width" : 113,
      "height" : 51
    },
    "textPosition" : {
      "x" : 3179,
      "y" : 601
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3292,
          "y" : 599
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3292,
          "y" : 599
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3084,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3222,
          "y" : 596
        },
        "to" : {
          "x" : 3190,
          "y" : 533
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3188,
          "y" : 530
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3188,
          "y" : 530
        }
      }
    } ]
  }, {
    "id" : 3155,
    "reactomeId" : 10144714,
    "displayName" : "IFN alpha/beta (IFNA/B)",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2547,
      "y" : 21
    },
    "minX" : 2498,
    "maxX" : 2597,
    "minY" : 3,
    "maxY" : 40,
    "prop" : {
      "x" : 2498,
      "y" : 3,
      "width" : 99,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2496,
      "y" : 4
    },
    "connectors" : [ ]
  }, {
    "id" : 3091,
    "reactomeId" : 10117285,
    "displayName" : "NKIRAS",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 3182,
      "y" : 455
    },
    "minX" : 3157,
    "maxX" : 3208,
    "minY" : 444,
    "maxY" : 510,
    "prop" : {
      "x" : 3157,
      "y" : 444,
      "width" : 51,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3157,
      "y" : 445
    },
    "connectors" : [ {
      "edgeId" : 3084,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 3182,
          "y" : 473
        },
        "to" : {
          "x" : 3183,
          "y" : 510
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3179,
          "y" : 510
        },
        "b" : {
          "x" : 3187,
          "y" : 510
        },
        "c" : {
          "x" : 3183,
          "y" : 510
        },
        "type" : "STOP",
        "centre" : {
          "x" : 3183,
          "y" : 510
        }
      }
    } ]
  }, {
    "id" : 3156,
    "reactomeId" : 10144712,
    "displayName" : "Ifnb1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2006,
      "y" : 17
    },
    "minX" : 1985,
    "maxX" : 2033,
    "minY" : 0,
    "maxY" : 29,
    "prop" : {
      "x" : 1985,
      "y" : 6,
      "width" : 42,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1986,
      "y" : 7
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2027,
          "y" : 6
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2027,
          "y" : 6
        }
      }
    },
    "connectors" : [ ]
  }, {
    "id" : 3093,
    "reactomeId" : 10146005,
    "displayName" : "PIN1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3127,
      "y" : 200
    },
    "minX" : 3109,
    "maxX" : 3169,
    "minY" : 171,
    "maxY" : 212,
    "prop" : {
      "x" : 3109,
      "y" : 189,
      "width" : 36,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3109,
      "y" : 190
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3145,
          "y" : 189
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3145,
          "y" : 189
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3092,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3143,
          "y" : 186
        },
        "to" : {
          "x" : 3169,
          "y" : 171
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3094,
    "reactomeId" : 10146010,
    "displayName" : "p-IRF3:p-IRF3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3127,
      "y" : 139
    },
    "minX" : 3081,
    "maxX" : 3180,
    "minY" : 122,
    "maxY" : 171,
    "prop" : {
      "x" : 3081,
      "y" : 128,
      "width" : 93,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3083,
      "y" : 130
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3174,
          "y" : 128
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3174,
          "y" : 128
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3092,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3142,
          "y" : 154
        },
        "to" : {
          "x" : 3169,
          "y" : 171
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3095,
    "reactomeId" : 10146012,
    "displayName" : "p-IRF3 dimer:PIN1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3293,
      "y" : 171
    },
    "minX" : 3234,
    "maxX" : 3358,
    "minY" : 154,
    "maxY" : 183,
    "prop" : {
      "x" : 3234,
      "y" : 160,
      "width" : 118,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3234,
      "y" : 162
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3352,
          "y" : 160
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3352,
          "y" : 160
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3092,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3097,
    "reactomeId" : 10146021,
    "displayName" : "K63polyUb-DDX58",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1418,
      "y" : 303
    },
    "minX" : 1357,
    "maxX" : 1485,
    "minY" : 286,
    "maxY" : 315,
    "prop" : {
      "x" : 1357,
      "y" : 292,
      "width" : 122,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1359,
      "y" : 293
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1479,
          "y" : 292
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1479,
          "y" : 292
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3096,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3098,
    "reactomeId" : 10103388,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1652,
      "y" : 302
    },
    "minX" : 1542,
    "maxX" : 1665,
    "minY" : 291,
    "maxY" : 314,
    "prop" : {
      "x" : 1640,
      "y" : 291,
      "width" : 25,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1640,
      "y" : 292
    },
    "connectors" : [ {
      "edgeId" : 3096,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1634,
          "y" : 301
        },
        "to" : {
          "x" : 1542,
          "y" : 301
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1627,
          "y" : 305
        },
        "b" : {
          "x" : 1634,
          "y" : 301
        },
        "c" : {
          "x" : 1627,
          "y" : 297
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1627,
          "y" : 297
        }
      }
    } ]
  }, {
    "id" : 3099,
    "reactomeId" : 10146023,
    "displayName" : "DDX58",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1698,
      "y" : 499
    },
    "minX" : 1542,
    "maxX" : 1730,
    "minY" : 301,
    "maxY" : 511,
    "prop" : {
      "x" : 1673,
      "y" : 488,
      "width" : 51,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1674,
      "y" : 489
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1724,
          "y" : 488
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1724,
          "y" : 488
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3096,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1688,
          "y" : 485
        },
        "to" : {
          "x" : 1542,
          "y" : 301
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1681,
          "y" : 482
        },
        "b" : {
          "x" : 1688,
          "y" : 485
        },
        "c" : {
          "x" : 1687,
          "y" : 477
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1687,
          "y" : 477
        }
      }
    } ]
  }, {
    "id" : 3100,
    "reactomeId" : 10110665,
    "displayName" : "CYLD",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1518,
      "y" : 214
    },
    "minX" : 1499,
    "maxX" : 1544,
    "minY" : 197,
    "maxY" : 293,
    "prop" : {
      "x" : 1499,
      "y" : 203,
      "width" : 39,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1499,
      "y" : 204
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1538,
          "y" : 203
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1538,
          "y" : 203
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3096,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1518,
          "y" : 229
        },
        "to" : {
          "x" : 1519,
          "y" : 285
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1519,
          "y" : 289
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1519,
          "y" : 289
        }
      }
    } ]
  }, {
    "id" : 3102,
    "reactomeId" : 10146037,
    "displayName" : "NLRX1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1356,
      "y" : 906
    },
    "minX" : 1289,
    "maxX" : 1386,
    "minY" : 834,
    "maxY" : 918,
    "prop" : {
      "x" : 1332,
      "y" : 895,
      "width" : 48,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1333,
      "y" : 896
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1380,
          "y" : 895
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1380,
          "y" : 895
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3101,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1345,
          "y" : 892
        },
        "to" : {
          "x" : 1289,
          "y" : 834
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3103,
    "reactomeId" : 10146032,
    "displayName" : "Mavs",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1194,
      "y" : 711
    },
    "minX" : 1174,
    "maxX" : 1289,
    "minY" : 694,
    "maxY" : 834,
    "prop" : {
      "x" : 1174,
      "y" : 700,
      "width" : 41,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1175,
      "y" : 701
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1215,
          "y" : 700
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1215,
          "y" : 700
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3101,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1202,
          "y" : 726
        },
        "to" : {
          "x" : 1289,
          "y" : 834
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3104,
    "reactomeId" : 10146039,
    "displayName" : "MAVS:NLRX1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1272,
      "y" : 909
    },
    "minX" : 1230,
    "maxX" : 1320,
    "minY" : 892,
    "maxY" : 921,
    "prop" : {
      "x" : 1230,
      "y" : 898,
      "width" : 84,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1230,
      "y" : 900
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1314,
          "y" : 898
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1314,
          "y" : 898
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3101,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3106,
    "reactomeId" : 10146240,
    "displayName" : "TAX1BP1:TNFAIP3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 163,
      "y" : 975
    },
    "minX" : 105,
    "maxX" : 229,
    "minY" : 958,
    "maxY" : 1005,
    "prop" : {
      "x" : 105,
      "y" : 964,
      "width" : 116,
      "height" : 23
    },
    "textPosition" : {
      "x" : 105,
      "y" : 966
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 221,
          "y" : 964
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 221,
          "y" : 964
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3105,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 188,
          "y" : 990
        },
        "to" : {
          "x" : 229,
          "y" : 1005
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3107,
    "reactomeId" : 10146246,
    "displayName" : "TBK1, IKBKE",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 159,
      "y" : 1042
    },
    "minX" : 119,
    "maxX" : 229,
    "minY" : 1005,
    "maxY" : 1054,
    "prop" : {
      "x" : 119,
      "y" : 1031,
      "width" : 81,
      "height" : 23
    },
    "textPosition" : {
      "x" : 120,
      "y" : 1032
    },
    "connectors" : [ {
      "edgeId" : 3105,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 180,
          "y" : 1025
        },
        "to" : {
          "x" : 229,
          "y" : 1005
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3108,
    "reactomeId" : 10146248,
    "displayName" : "TAX1BP1:TNFAIP3:TBK1/IKBKE",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 359,
      "y" : 1006
    },
    "minX" : 299,
    "maxX" : 425,
    "minY" : 982,
    "maxY" : 1025,
    "prop" : {
      "x" : 299,
      "y" : 988,
      "width" : 120,
      "height" : 37
    },
    "textPosition" : {
      "x" : 299,
      "y" : 990
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 419,
          "y" : 988
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 419,
          "y" : 988
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3105,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3110,
    "reactomeId" : 10117324,
    "displayName" : "NFKB1(1-433), NFKB2(1-454):RELA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3037,
      "y" : 254
    },
    "minX" : 2974,
    "maxX" : 3107,
    "minY" : 230,
    "maxY" : 273,
    "prop" : {
      "x" : 2974,
      "y" : 236,
      "width" : 127,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2974,
      "y" : 238
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3101,
          "y" : 236
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3101,
          "y" : 236
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3109,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3111,
    "reactomeId" : 10117366,
    "displayName" : "AGER ligands:AGER",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2943,
      "y" : 47
    },
    "minX" : 2882,
    "maxX" : 3028,
    "minY" : 30,
    "maxY" : 342,
    "prop" : {
      "x" : 2882,
      "y" : 36,
      "width" : 122,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2896,
      "y" : 24
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3004,
          "y" : 36
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3004,
          "y" : 36
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3109,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 2943,
          "y" : 62
        },
        "to" : {
          "x" : 2943,
          "y" : 337
        }
      }, {
        "from" : {
          "x" : 2943,
          "y" : 337
        },
        "to" : {
          "x" : 3028,
          "y" : 338
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3021,
          "y" : 342
        },
        "b" : {
          "x" : 3028,
          "y" : 338
        },
        "c" : {
          "x" : 3021,
          "y" : 334
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 3021,
          "y" : 334
        }
      }
    } ]
  }, {
    "id" : 3113,
    "reactomeId" : 10116963,
    "displayName" : "p-4S,T404-IRF3,p-S477,S479-IRF7",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1904,
      "y" : 482
    },
    "minX" : 1842,
    "maxX" : 2056,
    "minY" : 464,
    "maxY" : 501,
    "prop" : {
      "x" : 1842,
      "y" : 464,
      "width" : 125,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1846,
      "y" : 465
    },
    "connectors" : [ {
      "edgeId" : 3112,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 2044,
            "y" : 476
          },
          "b" : {
            "x" : 2056,
            "y" : 488
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2050,
            "y" : 482
          }
        }
      }
    } ]
  }, {
    "id" : 3114,
    "reactomeId" : 10150931,
    "displayName" : "IRF3-P:IRF7-P",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2383,
      "y" : 485
    },
    "minX" : 2156,
    "maxX" : 2448,
    "minY" : 433,
    "maxY" : 497,
    "prop" : {
      "x" : 2338,
      "y" : 474,
      "width" : 91,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2339,
      "y" : 476
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2429,
          "y" : 474
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2429,
          "y" : 474
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3112,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2335,
          "y" : 484
        },
        "to" : {
          "x" : 2156,
          "y" : 482
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2328,
          "y" : 488
        },
        "b" : {
          "x" : 2335,
          "y" : 484
        },
        "c" : {
          "x" : 2328,
          "y" : 480
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2328,
          "y" : 480
        }
      }
    }, {
      "edgeId" : 3116,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2397,
          "y" : 471
        },
        "to" : {
          "x" : 2448,
          "y" : 433
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3115,
    "reactomeId" : 10117516,
    "displayName" : "p-T,4S-IRF3:p-T,4S-IRF3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2294,
      "y" : 451
    },
    "minX" : 2156,
    "maxX" : 2448,
    "minY" : 427,
    "maxY" : 482,
    "prop" : {
      "x" : 2238,
      "y" : 433,
      "width" : 113,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2242,
      "y" : 435
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2351,
          "y" : 433
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2351,
          "y" : 433
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3112,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2235,
          "y" : 463
        },
        "to" : {
          "x" : 2156,
          "y" : 482
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2229,
          "y" : 469
        },
        "b" : {
          "x" : 2235,
          "y" : 463
        },
        "c" : {
          "x" : 2227,
          "y" : 461
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2227,
          "y" : 461
        }
      }
    }, {
      "edgeId" : 3116,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2354,
          "y" : 444
        },
        "to" : {
          "x" : 2448,
          "y" : 433
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3117,
    "reactomeId" : 10120166,
    "displayName" : "p-T,4S-IRF3:p-T,4S-IRF3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2383,
      "y" : 367
    },
    "minX" : 2327,
    "maxX" : 2481,
    "minY" : 343,
    "maxY" : 386,
    "prop" : {
      "x" : 2327,
      "y" : 349,
      "width" : 113,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2331,
      "y" : 351
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2440,
          "y" : 349
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2440,
          "y" : 349
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3116,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2443,
          "y" : 376
        },
        "to" : {
          "x" : 2481,
          "y" : 383
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2451,
          "y" : 373
        },
        "b" : {
          "x" : 2443,
          "y" : 376
        },
        "c" : {
          "x" : 2449,
          "y" : 381
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2449,
          "y" : 381
        }
      }
    } ]
  }, {
    "id" : 3118,
    "reactomeId" : 10150933,
    "displayName" : "IRF3-P:IRF7-P",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2494,
      "y" : 335
    },
    "minX" : 2449,
    "maxX" : 2546,
    "minY" : 285,
    "maxY" : 383,
    "prop" : {
      "x" : 2449,
      "y" : 324,
      "width" : 91,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2450,
      "y" : 326
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2540,
          "y" : 324
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2540,
          "y" : 324
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3116,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2490,
          "y" : 350
        },
        "to" : {
          "x" : 2481,
          "y" : 383
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2492,
          "y" : 358
        },
        "b" : {
          "x" : 2490,
          "y" : 350
        },
        "c" : {
          "x" : 2484,
          "y" : 356
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2484,
          "y" : 356
        }
      }
    }, {
      "edgeId" : 3119,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2497,
          "y" : 321
        },
        "to" : {
          "x" : 2509,
          "y" : 285
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3120,
    "reactomeId" : 10150937,
    "displayName" : "VAF (virus-activated factor)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2673,
      "y" : 286
    },
    "minX" : 2609,
    "maxX" : 2744,
    "minY" : 262,
    "maxY" : 305,
    "prop" : {
      "x" : 2609,
      "y" : 268,
      "width" : 129,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2617,
      "y" : 270
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2738,
          "y" : 268
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2738,
          "y" : 268
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3119,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3122,
    "reactomeId" : 10174882,
    "displayName" : "Tomm70",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3151,
      "y" : 902
    },
    "minX" : 3119,
    "maxX" : 3188,
    "minY" : 859,
    "maxY" : 914,
    "prop" : {
      "x" : 3120,
      "y" : 891,
      "width" : 62,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3120,
      "y" : 892
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3182,
          "y" : 891
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3182,
          "y" : 891
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3121,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3142,
          "y" : 888
        },
        "to" : {
          "x" : 3119,
          "y" : 859
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3123,
    "reactomeId" : 10146032,
    "displayName" : "Mavs",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3075,
      "y" : 901
    },
    "minX" : 3055,
    "maxX" : 3119,
    "minY" : 859,
    "maxY" : 913,
    "prop" : {
      "x" : 3055,
      "y" : 890,
      "width" : 41,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3056,
      "y" : 891
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3096,
          "y" : 890
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3096,
          "y" : 890
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3121,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3087,
          "y" : 887
        },
        "to" : {
          "x" : 3119,
          "y" : 859
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3124,
    "reactomeId" : 10213774,
    "displayName" : "MAVS:TOMM70",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3153,
      "y" : 791
    },
    "minX" : 3104,
    "maxX" : 3208,
    "minY" : 774,
    "maxY" : 803,
    "prop" : {
      "x" : 3104,
      "y" : 780,
      "width" : 98,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3104,
      "y" : 782
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3202,
          "y" : 780
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3202,
          "y" : 780
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3121,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3126,
    "reactomeId" : 10146244,
    "displayName" : "Tbk1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3124,
      "y" : 981
    },
    "minX" : 3014,
    "maxX" : 3150,
    "minY" : 956,
    "maxY" : 993,
    "prop" : {
      "x" : 3104,
      "y" : 970,
      "width" : 40,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3105,
      "y" : 971
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3144,
          "y" : 970
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3144,
          "y" : 970
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3125,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3101,
          "y" : 976
        },
        "to" : {
          "x" : 3014,
          "y" : 956
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3127,
    "reactomeId" : 10171003,
    "displayName" : "HSP90:HSP90",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 3120,
      "y" : 949
    },
    "minX" : 3014,
    "maxX" : 3165,
    "minY" : 938,
    "maxY" : 961,
    "prop" : {
      "x" : 3076,
      "y" : 938,
      "width" : 89,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3094,
      "y" : 932
    },
    "connectors" : [ {
      "edgeId" : 3125,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3070,
          "y" : 951
        },
        "to" : {
          "x" : 3014,
          "y" : 956
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3128,
    "reactomeId" : 10116942,
    "displayName" : "Irf3",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3042,
      "y" : 983
    },
    "minX" : 3014,
    "maxX" : 3065,
    "minY" : 956,
    "maxY" : 995,
    "prop" : {
      "x" : 3025,
      "y" : 972,
      "width" : 34,
      "height" : 23
    },
    "textPosition" : {
      "x" : 3028,
      "y" : 973
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3059,
          "y" : 972
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3059,
          "y" : 972
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3125,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3030,
          "y" : 969
        },
        "to" : {
          "x" : 3014,
          "y" : 956
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3129,
    "reactomeId" : 10213770,
    "displayName" : "HSP90:TBK1:IRF3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2913,
      "y" : 953
    },
    "minX" : 2858,
    "maxX" : 2975,
    "minY" : 936,
    "maxY" : 965,
    "prop" : {
      "x" : 2858,
      "y" : 942,
      "width" : 111,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2870,
      "y" : 930
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2969,
          "y" : 942
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2969,
          "y" : 942
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3125,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3134,
    "reactomeId" : 10116948,
    "displayName" : "IRF3,IRF7",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1792,
      "y" : 602
    },
    "minX" : 1761,
    "maxX" : 1824,
    "minY" : 591,
    "maxY" : 614,
    "prop" : {
      "x" : 1761,
      "y" : 591,
      "width" : 63,
      "height" : 23
    },
    "textPosition" : {
      "x" : 1773,
      "y" : 585
    },
    "connectors" : [ ]
  } ],
  "edges" : [ {
    "id" : 3105,
    "reactomeId" : 10146250,
    "displayName" : "TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 260,
      "y" : 1005
    },
    "minX" : 229,
    "maxX" : 296,
    "minY" : 999,
    "maxY" : 1011,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 229,
        "y" : 1005
      },
      "to" : {
        "x" : 260,
        "y" : 1005
      }
    }, {
      "from" : {
        "x" : 260,
        "y" : 1005
      },
      "to" : {
        "x" : 296,
        "y" : 1005
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 289,
        "y" : 1009
      },
      "b" : {
        "x" : 296,
        "y" : 1005
      },
      "c" : {
        "x" : 289,
        "y" : 1001
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 289,
        "y" : 1001
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 260,
        "y" : 1005
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 260,
        "y" : 1005
      }
    },
    "inputs" : [ {
      "id" : 3106,
      "points" : [ {
        "x" : 188,
        "y" : 990
      } ]
    }, {
      "id" : 3107,
      "points" : [ {
        "x" : 180,
        "y" : 1025
      } ]
    } ],
    "outputs" : [ {
      "id" : 3108
    } ]
  }, {
    "id" : 3076,
    "reactomeId" : 10145954,
    "displayName" : "Dimerization of p-IRF7",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2665,
      "y" : 531
    },
    "minX" : 2547,
    "maxX" : 2803,
    "minY" : 525,
    "maxY" : 537,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2803,
        "y" : 531
      },
      "to" : {
        "x" : 2665,
        "y" : 531
      }
    }, {
      "from" : {
        "x" : 2665,
        "y" : 531
      },
      "to" : {
        "x" : 2547,
        "y" : 531
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2554,
        "y" : 527
      },
      "b" : {
        "x" : 2547,
        "y" : 531
      },
      "c" : {
        "x" : 2554,
        "y" : 535
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2554,
        "y" : 535
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2665,
        "y" : 531
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2665,
        "y" : 531
      }
    },
    "inputs" : [ {
      "id" : 3077,
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 3078
    } ]
  }, {
    "id" : 3109,
    "reactomeId" : 10117368,
    "displayName" : "NF-kappa-B complex is transported from cytosol to nucleus",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3037,
      "y" : 338
    },
    "minX" : 3031,
    "maxX" : 3043,
    "minY" : 276,
    "maxY" : 494,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3037,
        "y" : 494
      },
      "to" : {
        "x" : 3037,
        "y" : 338
      }
    }, {
      "from" : {
        "x" : 3037,
        "y" : 338
      },
      "to" : {
        "x" : 3037,
        "y" : 276
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3041,
        "y" : 283
      },
      "b" : {
        "x" : 3037,
        "y" : 276
      },
      "c" : {
        "x" : 3033,
        "y" : 283
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3033,
        "y" : 283
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 3031,
        "y" : 332
      },
      "b" : {
        "x" : 3043,
        "y" : 344
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3037,
        "y" : 338
      }
    },
    "inputs" : [ {
      "id" : 3088
    } ],
    "outputs" : [ {
      "id" : 3110
    } ],
    "activators" : [ {
      "id" : 3111,
      "points" : [ {
        "x" : 2943,
        "y" : 62
      }, {
        "x" : 2943,
        "y" : 337
      } ]
    } ]
  }, {
    "id" : 3079,
    "reactomeId" : 10145952,
    "displayName" : "Translocation of p-IRF7:p-IRF7 to nucleus",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2596,
      "y" : 398
    },
    "minX" : 2503,
    "maxX" : 2602,
    "minY" : 381,
    "maxY" : 510,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2503,
        "y" : 510
      },
      "to" : {
        "x" : 2596,
        "y" : 398
      }
    }, {
      "from" : {
        "x" : 2596,
        "y" : 398
      },
      "to" : {
        "x" : 2598,
        "y" : 381
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2601,
        "y" : 388
      },
      "b" : {
        "x" : 2598,
        "y" : 381
      },
      "c" : {
        "x" : 2593,
        "y" : 387
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2593,
        "y" : 387
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2590,
        "y" : 392
      },
      "b" : {
        "x" : 2602,
        "y" : 404
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2596,
        "y" : 398
      }
    },
    "inputs" : [ {
      "id" : 3078
    } ],
    "outputs" : [ {
      "id" : 3080
    } ]
  }, {
    "id" : 3112,
    "reactomeId" : 10150941,
    "displayName" : "Dimerization of Phospho IRF3 or phospho IRF7",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2127,
      "y" : 482
    },
    "minX" : 1973,
    "maxX" : 2156,
    "minY" : 476,
    "maxY" : 488,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1973,
        "y" : 482
      },
      "to" : {
        "x" : 2127,
        "y" : 482
      }
    }, {
      "from" : {
        "x" : 2127,
        "y" : 482
      },
      "to" : {
        "x" : 2156,
        "y" : 482
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2121,
        "y" : 476
      },
      "b" : {
        "x" : 2133,
        "y" : 488
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2127,
        "y" : 482
      }
    },
    "inputs" : [ {
      "id" : 3113,
      "stoichiometry" : 3
    } ],
    "outputs" : [ {
      "id" : 3114,
      "points" : [ {
        "x" : 2335,
        "y" : 484
      } ]
    }, {
      "id" : 3115,
      "points" : [ {
        "x" : 2235,
        "y" : 463
      } ]
    }, {
      "id" : 3078,
      "points" : [ {
        "x" : 2431,
        "y" : 522
      } ]
    } ]
  }, {
    "id" : 3081,
    "reactomeId" : 10145964,
    "displayName" : "p-IRF7 dimer interacts with coactivator CBP/p300",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2694,
      "y" : 359
    },
    "minX" : 2683,
    "maxX" : 2712,
    "minY" : 353,
    "maxY" : 365,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2683,
        "y" : 359
      },
      "to" : {
        "x" : 2694,
        "y" : 359
      }
    }, {
      "from" : {
        "x" : 2694,
        "y" : 359
      },
      "to" : {
        "x" : 2712,
        "y" : 359
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2705,
        "y" : 363
      },
      "b" : {
        "x" : 2712,
        "y" : 359
      },
      "c" : {
        "x" : 2705,
        "y" : 355
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2705,
        "y" : 355
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2694,
        "y" : 359
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2694,
        "y" : 359
      }
    },
    "inputs" : [ {
      "id" : 3080,
      "points" : [ {
        "x" : 2659,
        "y" : 359
      } ]
    }, {
      "id" : 3082,
      "points" : [ {
        "x" : 2433,
        "y" : 313
      }, {
        "x" : 2600,
        "y" : 313
      } ]
    } ],
    "outputs" : [ {
      "id" : 3083
    } ]
  }, {
    "id" : 3116,
    "reactomeId" : 10150935,
    "displayName" : "Translocation of phosphorylated IRF3,IRF7 dimers into nucleus",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2479,
      "y" : 399
    },
    "minX" : 2448,
    "maxX" : 2485,
    "minY" : 383,
    "maxY" : 433,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2448,
        "y" : 433
      },
      "to" : {
        "x" : 2479,
        "y" : 399
      }
    }, {
      "from" : {
        "x" : 2479,
        "y" : 399
      },
      "to" : {
        "x" : 2481,
        "y" : 383
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2473,
        "y" : 393
      },
      "b" : {
        "x" : 2485,
        "y" : 405
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2479,
        "y" : 399
      }
    },
    "inputs" : [ {
      "id" : 3114,
      "points" : [ {
        "x" : 2397,
        "y" : 471
      } ]
    }, {
      "id" : 3115,
      "points" : [ {
        "x" : 2354,
        "y" : 444
      } ]
    }, {
      "id" : 3078,
      "points" : [ {
        "x" : 2481,
        "y" : 510
      } ]
    } ],
    "outputs" : [ {
      "id" : 3117,
      "points" : [ {
        "x" : 2443,
        "y" : 376
      } ]
    }, {
      "id" : 3118,
      "points" : [ {
        "x" : 2490,
        "y" : 350
      } ]
    }, {
      "id" : 3080,
      "points" : [ {
        "x" : 2543,
        "y" : 370
      } ]
    } ]
  }, {
    "id" : 3084,
    "reactomeId" : 10117287,
    "displayName" : "Active IKK Complex phosphorylates NF-kappa-B inhibitor",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3183,
      "y" : 519
    },
    "minX" : 3150,
    "maxX" : 3210,
    "minY" : 513,
    "maxY" : 525,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3210,
        "y" : 519
      },
      "to" : {
        "x" : 3183,
        "y" : 519
      }
    }, {
      "from" : {
        "x" : 3183,
        "y" : 519
      },
      "to" : {
        "x" : 3150,
        "y" : 519
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3177,
        "y" : 513
      },
      "b" : {
        "x" : 3189,
        "y" : 525
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3183,
        "y" : 519
      }
    },
    "inputs" : [ {
      "id" : 3085,
      "points" : [ {
        "x" : 3237,
        "y" : 487
      } ],
      "stoichiometry" : 4
    }, {
      "id" : 3086,
      "points" : [ {
        "x" : 3253,
        "y" : 532
      } ]
    } ],
    "outputs" : [ {
      "id" : 3087,
      "points" : [ {
        "x" : 3126,
        "y" : 541
      } ]
    }, {
      "id" : 3088,
      "points" : [ {
        "x" : 3105,
        "y" : 517
      } ]
    }, {
      "id" : 3089,
      "points" : [ {
        "x" : 3123,
        "y" : 484
      } ],
      "stoichiometry" : 4
    } ],
    "catalysts" : [ {
      "id" : 3090,
      "points" : [ {
        "x" : 3222,
        "y" : 596
      } ]
    } ],
    "inhibitors" : [ {
      "id" : 3091,
      "points" : [ {
        "x" : 3182,
        "y" : 473
      } ]
    } ]
  }, {
    "id" : 3119,
    "reactomeId" : 10150939,
    "displayName" : "Formation of VAF (virus-activated factor) complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2548,
      "y" : 285
    },
    "minX" : 2509,
    "maxX" : 2606,
    "minY" : 279,
    "maxY" : 291,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2509,
        "y" : 285
      },
      "to" : {
        "x" : 2548,
        "y" : 285
      }
    }, {
      "from" : {
        "x" : 2548,
        "y" : 285
      },
      "to" : {
        "x" : 2606,
        "y" : 285
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2599,
        "y" : 289
      },
      "b" : {
        "x" : 2606,
        "y" : 285
      },
      "c" : {
        "x" : 2599,
        "y" : 281
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2599,
        "y" : 281
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2548,
        "y" : 285
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2548,
        "y" : 285
      }
    },
    "inputs" : [ {
      "id" : 3118,
      "points" : [ {
        "x" : 2497,
        "y" : 321
      } ]
    }, {
      "id" : 3082,
      "points" : [ {
        "x" : 2433,
        "y" : 303
      } ]
    } ],
    "outputs" : [ {
      "id" : 3120
    } ]
  }, {
    "id" : 3121,
    "reactomeId" : 10213776,
    "displayName" : "MAVS binds TOMM70",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3119,
      "y" : 835
    },
    "minX" : 3113,
    "maxX" : 3144,
    "minY" : 806,
    "maxY" : 859,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3119,
        "y" : 859
      },
      "to" : {
        "x" : 3119,
        "y" : 835
      }
    }, {
      "from" : {
        "x" : 3119,
        "y" : 835
      },
      "to" : {
        "x" : 3144,
        "y" : 806
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3143,
        "y" : 814
      },
      "b" : {
        "x" : 3144,
        "y" : 806
      },
      "c" : {
        "x" : 3136,
        "y" : 809
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3136,
        "y" : 809
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3119,
        "y" : 835
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3119,
        "y" : 835
      }
    },
    "inputs" : [ {
      "id" : 3122,
      "points" : [ {
        "x" : 3142,
        "y" : 888
      } ]
    }, {
      "id" : 3123,
      "points" : [ {
        "x" : 3087,
        "y" : 887
      } ]
    } ],
    "outputs" : [ {
      "id" : 3124
    } ]
  }, {
    "id" : 3092,
    "reactomeId" : 10146014,
    "displayName" : "Interaction of PIN1 with p-IRF3",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3197,
      "y" : 171
    },
    "minX" : 3169,
    "maxX" : 3231,
    "minY" : 165,
    "maxY" : 177,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3169,
        "y" : 171
      },
      "to" : {
        "x" : 3197,
        "y" : 171
      }
    }, {
      "from" : {
        "x" : 3197,
        "y" : 171
      },
      "to" : {
        "x" : 3231,
        "y" : 171
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3224,
        "y" : 175
      },
      "b" : {
        "x" : 3231,
        "y" : 171
      },
      "c" : {
        "x" : 3224,
        "y" : 167
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3224,
        "y" : 167
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3197,
        "y" : 171
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3197,
        "y" : 171
      }
    },
    "inputs" : [ {
      "id" : 3093,
      "points" : [ {
        "x" : 3143,
        "y" : 186
      } ]
    }, {
      "id" : 3094,
      "points" : [ {
        "x" : 3142,
        "y" : 154
      } ]
    } ],
    "outputs" : [ {
      "id" : 3095
    } ]
  }, {
    "id" : 3125,
    "reactomeId" : 10213772,
    "displayName" : "HSP90 binds TBK1 and IRF3",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2996,
      "y" : 956
    },
    "minX" : 2972,
    "maxX" : 3014,
    "minY" : 950,
    "maxY" : 962,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3014,
        "y" : 956
      },
      "to" : {
        "x" : 2996,
        "y" : 956
      }
    }, {
      "from" : {
        "x" : 2996,
        "y" : 956
      },
      "to" : {
        "x" : 2972,
        "y" : 955
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2979,
        "y" : 951
      },
      "b" : {
        "x" : 2972,
        "y" : 955
      },
      "c" : {
        "x" : 2979,
        "y" : 959
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2979,
        "y" : 959
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2996,
        "y" : 956
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2996,
        "y" : 956
      }
    },
    "inputs" : [ {
      "id" : 3126,
      "points" : [ {
        "x" : 3101,
        "y" : 976
      } ]
    }, {
      "id" : 3127,
      "points" : [ {
        "x" : 3070,
        "y" : 951
      } ]
    }, {
      "id" : 3128,
      "points" : [ {
        "x" : 3030,
        "y" : 969
      } ]
    } ],
    "outputs" : [ {
      "id" : 3129
    } ]
  }, {
    "id" : 3096,
    "reactomeId" : 10146025,
    "displayName" : "CYLD mediated deubiquitination of DDX58 (RIG-I)",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1519,
      "y" : 301
    },
    "minX" : 1482,
    "maxX" : 1542,
    "minY" : 295,
    "maxY" : 307,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1482,
        "y" : 301
      },
      "to" : {
        "x" : 1519,
        "y" : 301
      }
    }, {
      "from" : {
        "x" : 1519,
        "y" : 301
      },
      "to" : {
        "x" : 1542,
        "y" : 301
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1513,
        "y" : 295
      },
      "b" : {
        "x" : 1525,
        "y" : 307
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1519,
        "y" : 301
      }
    },
    "inputs" : [ {
      "id" : 3097
    } ],
    "outputs" : [ {
      "id" : 3098,
      "points" : [ {
        "x" : 1634,
        "y" : 301
      } ]
    }, {
      "id" : 3099,
      "points" : [ {
        "x" : 1688,
        "y" : 485
      } ]
    } ],
    "catalysts" : [ {
      "id" : 3100,
      "points" : [ {
        "x" : 1518,
        "y" : 229
      } ]
    } ]
  }, {
    "id" : 3101,
    "reactomeId" : 10146041,
    "displayName" : "NLRX1 inhibits MAVS-DDX58 interaction",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1268,
      "y" : 863
    },
    "minX" : 1262,
    "maxX" : 1289,
    "minY" : 834,
    "maxY" : 895,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1289,
        "y" : 834
      },
      "to" : {
        "x" : 1268,
        "y" : 863
      }
    }, {
      "from" : {
        "x" : 1268,
        "y" : 863
      },
      "to" : {
        "x" : 1271,
        "y" : 895
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1266,
        "y" : 888
      },
      "b" : {
        "x" : 1271,
        "y" : 895
      },
      "c" : {
        "x" : 1274,
        "y" : 888
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1274,
        "y" : 888
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1268,
        "y" : 863
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1268,
        "y" : 863
      }
    },
    "inputs" : [ {
      "id" : 3102,
      "points" : [ {
        "x" : 1345,
        "y" : 892
      } ]
    }, {
      "id" : 3103,
      "points" : [ {
        "x" : 1202,
        "y" : 726
      } ]
    } ],
    "outputs" : [ {
      "id" : 3104
    } ]
  } ],
  "compartments" : [ {
    "id" : 3153,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 2647,
      "y" : 246
    },
    "minX" : 1919,
    "maxX" : 3376,
    "minY" : 92,
    "maxY" : 400,
    "prop" : {
      "x" : 1919,
      "y" : 92,
      "width" : 1457,
      "height" : 308
    },
    "textPosition" : {
      "x" : 3165,
      "y" : 352
    },
    "insets" : {
      "x" : 1929,
      "y" : 102,
      "width" : 1437,
      "height" : 288
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 3093, 3092, 3080, 3083, 3095, 3081, 3094, 3110, 3109, 3117, 3082, 3118, 3119, 3120, 3174, 3175, 3116, 3079, 3177, 3182, 3183 ]
  }, {
    "id" : 3158,
    "reactomeId" : 5462,
    "displayName" : "mitochondrion",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1591,
      "y" : 808
    },
    "minX" : 35,
    "maxX" : 3148,
    "minY" : 703,
    "maxY" : 914,
    "prop" : {
      "x" : 35,
      "y" : 703,
      "width" : 3113,
      "height" : 211
    },
    "textPosition" : {
      "x" : 2896,
      "y" : 782
    },
    "insets" : {
      "x" : 45,
      "y" : 713,
      "width" : 3093,
      "height" : 191
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 3102, 3104, 3101, 3103, 3121, 3124, 3123, 3122 ]
  }, {
    "id" : 3132,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1713,
      "y" : 569
    },
    "minX" : 0,
    "maxX" : 3427,
    "minY" : 47,
    "maxY" : 1092,
    "prop" : {
      "x" : 0,
      "y" : 47,
      "width" : 3427,
      "height" : 1045
    },
    "textPosition" : {
      "x" : 3300,
      "y" : 1034
    },
    "insets" : {
      "x" : 10,
      "y" : 57,
      "width" : 3407,
      "height" : 1025
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 3099, 3134, 3113, 3143, 3077, 3078, 3090, 3085, 3086, 3087, 3088, 3089, 3097, 3098, 3100, 3106, 3107, 3108, 3076, 3084, 3096, 3105, 3111, 3112, 3114, 3115, 3158, 3168, 3170, 3171, 3172, 3173, 3153, 3091, 3176, 3125, 3126, 3127, 3128, 3129, 3178, 3179, 3180, 3181 ]
  } ],
  "notes" : [ ],
  "links" : [ {
    "id" : 3168,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 2738,
      "y" : 600
    },
    "minX" : 1830,
    "maxX" : 2744,
    "minY" : 594,
    "maxY" : 660,
    "segments" : [ {
      "from" : {
        "x" : 2741,
        "y" : 660
      },
      "to" : {
        "x" : 2738,
        "y" : 600
      }
    }, {
      "from" : {
        "x" : 2738,
        "y" : 600
      },
      "to" : {
        "x" : 1830,
        "y" : 601
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2732,
        "y" : 594
      },
      "b" : {
        "x" : 2744,
        "y" : 606
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2738,
        "y" : 600
      }
    },
    "inputs" : [ {
      "id" : 3143
    } ],
    "outputs" : [ {
      "id" : 3134
    } ]
  }, {
    "id" : 3169,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 2261,
      "y" : 18
    },
    "minX" : 2030,
    "maxX" : 2492,
    "minY" : 12,
    "maxY" : 24,
    "segments" : [ {
      "from" : {
        "x" : 2030,
        "y" : 17
      },
      "to" : {
        "x" : 2492,
        "y" : 20
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2255,
        "y" : 12
      },
      "b" : {
        "x" : 2267,
        "y" : 24
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2261,
        "y" : 18
      }
    },
    "inputs" : [ {
      "id" : 3156
    } ],
    "outputs" : [ {
      "id" : 3155
    } ]
  }, {
    "id" : 3173,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 2421,
      "y" : 560
    },
    "minX" : 1953,
    "maxX" : 2814,
    "minY" : 507,
    "maxY" : 566,
    "segments" : [ {
      "from" : {
        "x" : 2814,
        "y" : 546
      },
      "to" : {
        "x" : 2731,
        "y" : 561
      }
    }, {
      "from" : {
        "x" : 2731,
        "y" : 561
      },
      "to" : {
        "x" : 2111,
        "y" : 559
      }
    }, {
      "from" : {
        "x" : 2111,
        "y" : 559
      },
      "to" : {
        "x" : 1953,
        "y" : 507
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2415,
        "y" : 554
      },
      "b" : {
        "x" : 2427,
        "y" : 566
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2421,
        "y" : 560
      }
    },
    "inputs" : [ {
      "id" : 3077
    } ],
    "outputs" : [ {
      "id" : 3113
    } ]
  } ],
  "shadows" : [ {
    "id" : 3174,
    "reactomeId" : 10222863,
    "displayName" : "TRAF6 mediated NF-kB activation",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 3125,
      "y" : 343
    },
    "minX" : 2872,
    "maxX" : 3378,
    "minY" : 26,
    "maxY" : 660,
    "prop" : {
      "x" : 2872,
      "y" : 26,
      "width" : 506,
      "height" : 92
    },
    "points" : [ {
      "x" : 2872,
      "y" : 26
    }, {
      "x" : 3378,
      "y" : 26
    }, {
      "x" : 3378,
      "y" : 660
    }, {
      "x" : 2872,
      "y" : 660
    } ],
    "colour" : "#4684ee"
  }, {
    "id" : 3175,
    "reactomeId" : 10224035,
    "displayName" : "TRAF6 mediated IRF7 activation",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 2629,
      "y" : 409
    },
    "minX" : 2322,
    "maxX" : 2936,
    "minY" : 258,
    "maxY" : 560,
    "prop" : {
      "x" : 2666,
      "y" : 314,
      "width" : 206,
      "height" : 246
    },
    "points" : [ {
      "x" : 2322,
      "y" : 258
    }, {
      "x" : 2936,
      "y" : 258
    }, {
      "x" : 2936,
      "y" : 560
    }, {
      "x" : 2322,
      "y" : 560
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 3176,
    "reactomeId" : 10224047,
    "displayName" : "Negative regulators of DDX58/IFIH1 signaling",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1728,
      "y" : 591
    },
    "minX" : 95,
    "maxX" : 3362,
    "minY" : 118,
    "maxY" : 1064,
    "prop" : {
      "x" : 95,
      "y" : 660,
      "width" : 3267,
      "height" : 404
    },
    "points" : [ {
      "x" : 95,
      "y" : 118
    }, {
      "x" : 3362,
      "y" : 118
    }, {
      "x" : 3362,
      "y" : 1064
    }, {
      "x" : 95,
      "y" : 1064
    } ],
    "colour" : "#008000"
  }, {
    "id" : 3177,
    "reactomeId" : 10224103,
    "displayName" : "TRAF3-dependent IRF activation pathway",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 2249,
      "y" : 437
    },
    "minX" : 1832,
    "maxX" : 2666,
    "minY" : 314,
    "maxY" : 560,
    "prop" : {
      "x" : 1832,
      "y" : 314,
      "width" : 490,
      "height" : 246
    },
    "points" : [ {
      "x" : 1832,
      "y" : 314
    }, {
      "x" : 2666,
      "y" : 314
    }, {
      "x" : 2666,
      "y" : 560
    }, {
      "x" : 1832,
      "y" : 560
    } ],
    "colour" : "#666666"
  } ],
  "minX" : 0,
  "maxX" : 3427,
  "minY" : 0,
  "maxY" : 1092,
  "disease" : false
}