{
  "dbId" : 10224347,
  "stableId" : "R-RNO-157118",
  "displayName" : "Signaling by NOTCH",
  "nodes" : [ {
    "id" : 104669,
    "reactomeId" : 10224345,
    "displayName" : "Signaling by NOTCH1",
    "schemaClass" : "Pathway",
    "renderableClass" : "ProcessNode",
    "position" : {
      "x" : 327,
      "y" : 26
    },
    "minX" : 251,
    "maxX" : 403,
    "minY" : 0,
    "maxY" : 52,
    "prop" : {
      "x" : 251,
      "y" : 0,
      "width" : 152,
      "height" : 52
    },
    "textPosition" : {
      "x" : 254,
      "y" : 11
    },
    "connectors" : [ ]
  }, {
    "id" : 104668,
    "reactomeId" : 10224351,
    "displayName" : "Pre-NOTCH Expression and Processing",
    "schemaClass" : "Pathway",
    "renderableClass" : "ProcessNode",
    "position" : {
      "x" : 88,
      "y" : 142
    },
    "minX" : 0,
    "maxX" : 177,
    "minY" : 107,
    "maxY" : 177,
    "prop" : {
      "x" : 0,
      "y" : 107,
      "width" : 177,
      "height" : 70
    },
    "textPosition" : {
      "x" : 9,
      "y" : 120
    },
    "connectors" : [ ]
  }, {
    "id" : 104671,
    "reactomeId" : 10225277,
    "displayName" : "Signaling by NOTCH4",
    "schemaClass" : "Pathway",
    "renderableClass" : "ProcessNode",
    "position" : {
      "x" : 331,
      "y" : 272
    },
    "minX" : 253,
    "maxX" : 410,
    "minY" : 250,
    "maxY" : 295,
    "prop" : {
      "x" : 253,
      "y" : 250,
      "width" : 157,
      "height" : 45
    },
    "textPosition" : {
      "x" : 259,
      "y" : 258
    },
    "connectors" : [ ]
  }, {
    "id" : 104670,
    "reactomeId" : 10224417,
    "displayName" : "Signaling by NOTCH3",
    "schemaClass" : "Pathway",
    "renderableClass" : "ProcessNode",
    "position" : {
      "x" : 327,
      "y" : 187
    },
    "minX" : 250,
    "maxX" : 405,
    "minY" : 161,
    "maxY" : 213,
    "prop" : {
      "x" : 250,
      "y" : 161,
      "width" : 155,
      "height" : 52
    },
    "textPosition" : {
      "x" : 255,
      "y" : 172
    },
    "connectors" : [ ]
  } ],
  "edges" : [ ],
  "compartments" : [ ],
  "notes" : [ ],
  "links" : [ {
    "id" : 104672,
    "renderableClass" : "FlowLine",
    "position" : {
      "x" : 216,
      "y" : 79
    },
    "minX" : 161,
    "maxX" : 271,
    "minY" : 55,
    "maxY" : 104,
    "segments" : [ {
      "from" : {
        "x" : 161,
        "y" : 104
      },
      "to" : {
        "x" : 271,
        "y" : 55
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 266,
        "y" : 61
      },
      "b" : {
        "x" : 271,
        "y" : 55
      },
      "c" : {
        "x" : 263,
        "y" : 54
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 263,
        "y" : 54
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 210,
        "y" : 73
      },
      "b" : {
        "x" : 222,
        "y" : 85
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 216,
        "y" : 79
      }
    },
    "inputs" : [ {
      "id" : 104668
    } ],
    "outputs" : [ {
      "id" : 104669
    } ]
  }, {
    "id" : 104675,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 220,
      "y" : 213
    },
    "minX" : 154,
    "maxX" : 287,
    "minY" : 180,
    "maxY" : 247,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 154,
        "y" : 180
      },
      "to" : {
        "x" : 287,
        "y" : 247
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 279,
        "y" : 247
      },
      "b" : {
        "x" : 287,
        "y" : 247
      },
      "c" : {
        "x" : 283,
        "y" : 240
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 283,
        "y" : 240
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 214,
        "y" : 207
      },
      "b" : {
        "x" : 226,
        "y" : 219
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 220,
        "y" : 213
      }
    },
    "inputs" : [ {
      "id" : 104668
    } ],
    "outputs" : [ {
      "id" : 104671
    } ]
  }, {
    "id" : 104674,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 213,
      "y" : 164
    },
    "minX" : 180,
    "maxX" : 247,
    "minY" : 158,
    "maxY" : 171,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 180,
        "y" : 158
      },
      "to" : {
        "x" : 247,
        "y" : 171
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 239,
        "y" : 174
      },
      "b" : {
        "x" : 247,
        "y" : 171
      },
      "c" : {
        "x" : 241,
        "y" : 166
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 241,
        "y" : 166
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 207,
        "y" : 158
      },
      "b" : {
        "x" : 219,
        "y" : 170
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 213,
        "y" : 164
      }
    },
    "inputs" : [ {
      "id" : 104668
    } ],
    "outputs" : [ {
      "id" : 104670
    } ]
  } ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 410,
  "minY" : 0,
  "maxY" : 295,
  "disease" : false
}