{
  "dbId" : 10224273,
  "stId" : "R-RNO-1566948",
  "speciesName" : "Rattus norvegicus",
  "nodes" : [ {
    "dbId" : 10163600,
    "stId" : "R-RNO-2022132",
    "displayName" : "Lysyl oxidases:Cu2+ [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55136 ],
    "parents" : [ ],
    "children" : [ 10161584, 437295 ]
  }, {
    "dbId" : 10142615,
    "stId" : "R-RNO-114707",
    "displayName" : "Tgfb3 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q07258",
    "standardIdentifier" : "uniprot:Q07258",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Tgfb3" ],
    "parents" : [ 10166082 ],
    "children" : [ ]
  }, {
    "dbId" : 10163593,
    "stId" : "R-RNO-2159856",
    "displayName" : "FURIN [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 55118 ],
    "identifier" : "P23377",
    "standardIdentifier" : "uniprot:P23377",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10163587,
    "stId" : "R-RNO-2161254",
    "displayName" : "Fibrillins:MFAP2,MFAP5:Tropoelastin aggregate [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55133 ],
    "parents" : [ ],
    "children" : [ 10163585, 10156515, 10156537 ]
  }, {
    "dbId" : 10163585,
    "stId" : "R-RNO-2161342",
    "displayName" : "Tropoelastin aggregate [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55130 ],
    "parents" : [ 10163587 ],
    "children" : [ 10156345 ]
  }, {
    "dbId" : 10163591,
    "stId" : "R-RNO-2159838",
    "displayName" : "Fbn1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 55117 ],
    "identifier" : "G3V9M6",
    "standardIdentifier" : "uniprot:G3V9M6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Fbn1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10167430,
    "stId" : "R-RNO-2537655",
    "displayName" : "FBLN1, FBLN2:Fibronectin matrix [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55169 ],
    "parents" : [ ],
    "children" : [ 10128757, 10156508 ]
  }, {
    "dbId" : 10128824,
    "stId" : "R-RNO-1299497",
    "displayName" : "Integrin alphaVbeta5 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10166066, 10166226 ],
    "children" : [ 10127831, 10128822 ]
  }, {
    "dbId" : 10128830,
    "stId" : "R-RNO-216307",
    "displayName" : "Integrin alphaVbeta8 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10166066, 10166226 ],
    "children" : [ 10127831, 10128828 ]
  }, {
    "dbId" : 10128828,
    "stId" : "R-RNO-216318",
    "displayName" : "Itgb8 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "A0A0G2JVU1",
    "standardIdentifier" : "uniprot:A0A0G2JVU1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Itgb8" ],
    "parents" : [ 10128830 ],
    "children" : [ ]
  }, {
    "dbId" : 10128818,
    "stId" : "R-RNO-215971",
    "displayName" : "Vtn [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q7TQ11",
    "standardIdentifier" : "uniprot:Q7TQ11",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Vtn" ],
    "parents" : [ 10164300 ],
    "children" : [ ]
  }, {
    "dbId" : 437295,
    "stId" : "R-ALL-437295",
    "displayName" : "Cu2+ [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "29036",
    "standardIdentifier" : "chebi:29036",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10163600 ],
    "children" : [ ]
  }, {
    "dbId" : 10161584,
    "stId" : "R-RNO-2022119",
    "displayName" : "Lysyl oxidases [extracellular region]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 48895,
    "parents" : [ 10163600 ],
    "children" : [ 10161574, 10161576, 10161580, 10161582, 10161578 ]
  }, {
    "dbId" : 10128822,
    "stId" : "R-RNO-215948",
    "displayName" : "ITGB5 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "A0A8I6AQL1",
    "standardIdentifier" : "uniprot:A0A8I6AQL1",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10128824 ],
    "children" : [ ]
  }, {
    "dbId" : 10161578,
    "stId" : "R-RNO-2022136",
    "displayName" : "LOXL2(?-774) [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "B5DF27",
    "standardIdentifier" : "uniprot:B5DF27",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10161584 ],
    "children" : [ ]
  }, {
    "dbId" : 10161576,
    "stId" : "R-RNO-2022107",
    "displayName" : "Loxl1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q5FWS5",
    "standardIdentifier" : "uniprot:Q5FWS5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Loxl1" ],
    "parents" : [ 10161584 ],
    "children" : [ ]
  }, {
    "dbId" : 10161582,
    "stId" : "R-RNO-2022098",
    "displayName" : "Loxl4 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "D4A9V5",
    "standardIdentifier" : "uniprot:D4A9V5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Loxl4" ],
    "parents" : [ 10161584 ],
    "children" : [ ]
  }, {
    "dbId" : 10161580,
    "stId" : "R-RNO-2022122",
    "displayName" : "Loxl3 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "D3ZP82",
    "standardIdentifier" : "uniprot:D3ZP82",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Loxl3" ],
    "parents" : [ 10161584 ],
    "children" : [ ]
  }, {
    "dbId" : 10161574,
    "stId" : "R-RNO-2022085",
    "displayName" : "LOX [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "P16636",
    "standardIdentifier" : "uniprot:P16636",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10161584 ],
    "children" : [ ]
  }, {
    "dbId" : 10127833,
    "stId" : "R-RNO-210216",
    "displayName" : "Integrin alphaVbeta3 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10166039, 10166066, 10166226 ],
    "children" : [ 10127831, 10113031 ]
  }, {
    "dbId" : 10156508,
    "stId" : "R-RNO-2161298",
    "displayName" : "Fbln2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 55168 ],
    "identifier" : "G3V6X1",
    "standardIdentifier" : "uniprot:G3V6X1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Fbln2" ],
    "parents" : [ 10167430, 10156521 ],
    "children" : [ ]
  }, {
    "dbId" : 10166226,
    "stId" : "R-RNO-2396408",
    "displayName" : "LAP3-binding integrins [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 55157 ],
    "parents" : [ 10166228 ],
    "children" : [ 10128753, 10128830, 10127833, 10128824, 10128744 ]
  }, {
    "dbId" : 10127831,
    "stId" : "R-RNO-210013",
    "displayName" : "Itgav [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "F1LZX9",
    "standardIdentifier" : "uniprot:F1LZX9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10128744, 10128753, 10127833, 10128824, 10128830 ],
    "children" : [ ]
  }, {
    "dbId" : 10166228,
    "stId" : "R-RNO-2396121",
    "displayName" : "TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55159 ],
    "parents" : [ ],
    "children" : [ 10166226, 10166082 ]
  }, {
    "dbId" : 10156539,
    "stId" : "R-RNO-2161360",
    "displayName" : "Elastic fibre [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55135 ],
    "parents" : [ 10156541 ],
    "children" : [ 10156537, 10156347 ]
  }, {
    "dbId" : 10166265,
    "stId" : "R-RNO-2396217",
    "displayName" : "Fibrillins:BMP2,4,7,10,GF5 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55162 ],
    "parents" : [ ],
    "children" : [ 10166263, 10156525 ]
  }, {
    "dbId" : 10156537,
    "stId" : "R-RNO-2396329",
    "displayName" : "Fibrilins:MFAP2,MFAP5 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55127 ],
    "parents" : [ 10163587, 10156539 ],
    "children" : [ 10156535, 10156525 ]
  }, {
    "dbId" : 10156541,
    "stId" : "R-RNO-2395337",
    "displayName" : "Elastic fibre:Fibulins [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55143 ],
    "parents" : [ 10164293 ],
    "children" : [ 10156521, 10156539 ]
  }, {
    "dbId" : 10166257,
    "stId" : "R-RNO-2396409",
    "displayName" : "Bmp10 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q4AEG6",
    "standardIdentifier" : "uniprot:Q4AEG6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Bmp10" ],
    "parents" : [ 10166263 ],
    "children" : [ ]
  }, {
    "dbId" : 10156529,
    "stId" : "R-RNO-2161346",
    "displayName" : "Mfap2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "D3Z952",
    "standardIdentifier" : "uniprot:D3Z952",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Mfap2" ],
    "parents" : [ 10156535 ],
    "children" : [ ]
  }, {
    "dbId" : 10166263,
    "stId" : "R-RNO-2396226",
    "displayName" : "BMP2,4,7,10,GF5 [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 55161 ],
    "parents" : [ 10166265 ],
    "children" : [ 10166261, 10166246, 10166257, 10166242, 10166250 ]
  }, {
    "dbId" : 10156535,
    "stId" : "R-RNO-2396477",
    "displayName" : "MFAP2, MFAP5 [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 55126 ],
    "parents" : [ 10156537 ],
    "children" : [ 10156533, 10156529 ]
  }, {
    "dbId" : 10166261,
    "stId" : "R-RNO-2396129",
    "displayName" : "Gdf5 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "M0RAY4",
    "standardIdentifier" : "uniprot:M0RAY4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Gdf5" ],
    "parents" : [ 10166263 ],
    "children" : [ ]
  }, {
    "dbId" : 10156533,
    "stId" : "R-RNO-2161230",
    "displayName" : "Mfap5 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "A0A0G2K9S8",
    "standardIdentifier" : "uniprot:A0A0G2K9S8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Mfap5" ],
    "parents" : [ 10156535 ],
    "children" : [ ]
  }, {
    "dbId" : 10156523,
    "stId" : "R-RNO-2159853",
    "displayName" : "Fbn1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 55116 ],
    "identifier" : "G3V9M6",
    "standardIdentifier" : "uniprot:G3V9M6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Fbn1" ],
    "parents" : [ 10156525 ],
    "children" : [ ]
  }, {
    "dbId" : 10166250,
    "stId" : "R-RNO-206223",
    "displayName" : "Bmp7 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "G3V6W8",
    "standardIdentifier" : "uniprot:G3V6W8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Bmp7" ],
    "parents" : [ 10166263 ],
    "children" : [ ]
  }, {
    "dbId" : 10156521,
    "stId" : "R-RNO-2395327",
    "displayName" : "Fibulins [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 55142 ],
    "parents" : [ 10156541 ],
    "children" : [ 10156519, 10156515, 10156508 ]
  }, {
    "dbId" : 10156525,
    "stId" : "R-RNO-2159874",
    "displayName" : "Fibrillin-1 [extracellular region]",
    "schemaClass" : "Polymer",
    "speciesId" : 48895,
    "diagramIds" : [ 55120, 55124 ],
    "parents" : [ 10166041, 10166265, 10156537, 10166035 ],
    "children" : [ 10156523 ]
  }, {
    "dbId" : 10166242,
    "stId" : "R-RNO-2396130",
    "displayName" : "Bmp2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "P49001",
    "standardIdentifier" : "uniprot:P49001",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Bmp2" ],
    "parents" : [ 10166263 ],
    "children" : [ ]
  }, {
    "dbId" : 10156515,
    "stId" : "R-RNO-2161278",
    "displayName" : "Fbln5 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 55132 ],
    "identifier" : "Q9WVH8",
    "standardIdentifier" : "uniprot:Q9WVH8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Fbln5" ],
    "parents" : [ 10163587, 10156521 ],
    "children" : [ ]
  }, {
    "dbId" : 10166246,
    "stId" : "R-RNO-2396280",
    "displayName" : "Bmp4 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q06826",
    "standardIdentifier" : "uniprot:Q06826",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Bmp4" ],
    "parents" : [ 10166263 ],
    "children" : [ ]
  }, {
    "dbId" : 10156519,
    "stId" : "R-RNO-2161231",
    "displayName" : "Efemp2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "A0A8I5Y8F2",
    "standardIdentifier" : "uniprot:A0A8I5Y8F2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Efemp2" ],
    "parents" : [ 10156521 ],
    "children" : [ ]
  }, {
    "dbId" : 10166041,
    "stId" : "R-RNO-2396200",
    "displayName" : "Fibrilin-1:Fibrilin-binding integrins [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55122 ],
    "parents" : [ ],
    "children" : [ 10166039, 10156525 ]
  }, {
    "dbId" : 10129182,
    "stId" : "R-RNO-265402",
    "displayName" : "Fbn1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 55115 ],
    "identifier" : "G3V9M6",
    "standardIdentifier" : "uniprot:G3V9M6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Fbn1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10166035,
    "stId" : "R-RNO-2396177",
    "displayName" : "LTBPs:Fibrillin-1 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55165 ],
    "parents" : [ ],
    "children" : [ 10166033, 10156525 ]
  }, {
    "dbId" : 10166033,
    "stId" : "R-RNO-2396175",
    "displayName" : "LTBPs [extracellular region]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 48895,
    "diagramIds" : [ 55164 ],
    "parents" : [ 10166035 ],
    "children" : [ 10166023, 10166019, 10166031, 10166027 ]
  }, {
    "dbId" : 10166039,
    "stId" : "R-RNO-2396352",
    "displayName" : "Fibrilin-binding integrins [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 55121 ],
    "parents" : [ 10166041 ],
    "children" : [ 10125937, 10128753, 10127833 ]
  }, {
    "dbId" : 10117910,
    "stId" : "R-RNO-170852",
    "displayName" : "Dimeric TGFB1 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10120047 ],
    "children" : [ 10117908 ]
  }, {
    "dbId" : 10117908,
    "stId" : "R-RNO-170838",
    "displayName" : "Tgfb1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "P17246",
    "standardIdentifier" : "uniprot:P17246",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Tgfb1" ],
    "parents" : [ 10117910 ],
    "children" : [ ]
  }, {
    "dbId" : 10166027,
    "stId" : "R-RNO-2161340",
    "displayName" : "LTBP2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "O35806",
    "standardIdentifier" : "uniprot:O35806",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10166033 ],
    "children" : [ ]
  }, {
    "dbId" : 10166031,
    "stId" : "R-RNO-2161253",
    "displayName" : "Ltbp3 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "A0A8I6AVC5",
    "standardIdentifier" : "uniprot:A0A8I6AVC5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ltbp3" ],
    "parents" : [ 10166074, 10166033 ],
    "children" : [ ]
  }, {
    "dbId" : 10166019,
    "stId" : "R-RNO-2161391",
    "displayName" : "Ltbp1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q00918",
    "standardIdentifier" : "uniprot:Q00918",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ltbp1" ],
    "parents" : [ 10166070, 10166068, 10166074, 10166033 ],
    "children" : [ ]
  }, {
    "dbId" : 10166023,
    "stId" : "R-RNO-2161309",
    "displayName" : "Ltbp4 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 55149 ],
    "identifier" : "D4A917",
    "standardIdentifier" : "uniprot:D4A917",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ltbp4" ],
    "parents" : [ 10166033, 10166096 ],
    "children" : [ ]
  }, {
    "dbId" : 10113031,
    "stId" : "R-RNO-57600",
    "displayName" : "ITGB3 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q8R2H2",
    "standardIdentifier" : "uniprot:Q8R2H2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Itgb3" ],
    "parents" : [ 10127833 ],
    "children" : [ ]
  }, {
    "dbId" : 10156347,
    "stId" : "R-RNO-2161232",
    "displayName" : "Elastin [extracellular region]",
    "schemaClass" : "Polymer",
    "speciesId" : 48895,
    "parents" : [ 10156539 ],
    "children" : [ 10156345 ]
  }, {
    "dbId" : 10166074,
    "stId" : "R-RNO-2395372",
    "displayName" : "LTBP1, LTBP3 [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 55146 ],
    "parents" : [ 10166086, 10166088, 10166090 ],
    "children" : [ 10166019, 10166031 ]
  }, {
    "dbId" : 10164281,
    "stId" : "R-RNO-2161398",
    "displayName" : "Emilin-2 polymer [extracellular region]",
    "schemaClass" : "Polymer",
    "speciesId" : 48895,
    "parents" : [ 10164291 ],
    "children" : [ 10164279 ]
  }, {
    "dbId" : 10156345,
    "stId" : "R-RNO-1454880",
    "displayName" : "Eln [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "diagramIds" : [ 55129 ],
    "identifier" : "Q99372",
    "standardIdentifier" : "uniprot:Q99372",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Eln" ],
    "parents" : [ 10163585, 10156347 ],
    "children" : [ ]
  }, {
    "dbId" : 10164287,
    "stId" : "R-RNO-2161306",
    "displayName" : "Emilin-3 trimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10164289 ],
    "children" : [ 10164285 ]
  }, {
    "dbId" : 10166078,
    "stId" : "R-RNO-2395253",
    "displayName" : "TGFB2:LAP2 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10166088, 10166084 ],
    "children" : [ 10117987, 10166076 ]
  }, {
    "dbId" : 10164285,
    "stId" : "R-RNO-2161272",
    "displayName" : "Emilin3 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "D3ZQ65",
    "standardIdentifier" : "uniprot:D3ZQ65",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Emilin3" ],
    "parents" : [ 10164287 ],
    "children" : [ ]
  }, {
    "dbId" : 10166076,
    "stId" : "R-RNO-2395269",
    "displayName" : "Tgfb2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q07257",
    "standardIdentifier" : "uniprot:Q07257",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Tgfb2" ],
    "parents" : [ 10166078 ],
    "children" : [ ]
  }, {
    "dbId" : 10166066,
    "stId" : "R-RNO-2396176",
    "displayName" : "LAP1 binding-integrins [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 55154 ],
    "parents" : [ 10166070 ],
    "children" : [ 10128742, 10128753, 10128830, 10127833, 10128824, 10128744 ]
  }, {
    "dbId" : 10164273,
    "stId" : "R-RNO-2161354",
    "displayName" : "Emilin-1 polymer [extracellular region]",
    "schemaClass" : "Polymer",
    "speciesId" : 48895,
    "parents" : [ 10164291 ],
    "children" : [ 10164271 ]
  }, {
    "dbId" : 10164279,
    "stId" : "R-RNO-2161392",
    "displayName" : "Emilin-2 trimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10164281 ],
    "children" : [ 10164277 ]
  }, {
    "dbId" : 10166070,
    "stId" : "R-RNO-2396201",
    "displayName" : "LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55155 ],
    "parents" : [ ],
    "children" : [ 10166066, 10166019, 10120047 ]
  }, {
    "dbId" : 10164277,
    "stId" : "R-RNO-2161394",
    "displayName" : "Emilin2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "F1LXD8",
    "standardIdentifier" : "uniprot:F1LXD8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Emilin2" ],
    "parents" : [ 10164279 ],
    "children" : [ ]
  }, {
    "dbId" : 10166068,
    "stId" : "R-RNO-9737594",
    "displayName" : "LTBP1:TGFB1:LAP1 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55153 ],
    "parents" : [ ],
    "children" : [ 10166019, 10120047 ]
  }, {
    "dbId" : 10164271,
    "stId" : "R-RNO-2161295",
    "displayName" : "Emilin-1 trimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10164273 ],
    "children" : [ 10164269 ]
  }, {
    "dbId" : 10164269,
    "stId" : "R-RNO-2161355",
    "displayName" : "Emilin1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "D3Z9E1",
    "standardIdentifier" : "uniprot:D3Z9E1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Emilin1" ],
    "parents" : [ 10164271 ],
    "children" : [ ]
  }, {
    "dbId" : 10123558,
    "stId" : "R-RNO-57596",
    "displayName" : "ITGB1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "P49134",
    "standardIdentifier" : "uniprot:P49134",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Itgb1" ],
    "parents" : [ 10125937, 10128742, 10128744 ],
    "children" : [ ]
  }, {
    "dbId" : 10166096,
    "stId" : "R-RNO-2395326",
    "displayName" : "LTBP4:TGFB1:LAP1 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55151 ],
    "parents" : [ ],
    "children" : [ 10166023, 10120047 ]
  }, {
    "dbId" : 10166090,
    "stId" : "R-RNO-9736822",
    "displayName" : "LTBP1,LTBP3:TGFB3:LAP3 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10166092 ],
    "children" : [ 10166082, 10166074 ]
  }, {
    "dbId" : 10164298,
    "stId" : "R-RNO-2161384",
    "displayName" : "Mfap4 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "G3V6A9",
    "standardIdentifier" : "uniprot:G3V6A9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Mfap4" ],
    "parents" : [ 10164300 ],
    "children" : [ ]
  }, {
    "dbId" : 10166088,
    "stId" : "R-RNO-9736823",
    "displayName" : "LTBP1,LTBP3:TGFB2:LAP2 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10166092 ],
    "children" : [ 10166078, 10166074 ]
  }, {
    "dbId" : 10164302,
    "stId" : "R-RNO-2161325",
    "displayName" : "Elastic fibre with associated proteins [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55140 ],
    "parents" : [ ],
    "children" : [ 10164293, 10164300 ]
  }, {
    "dbId" : 10166092,
    "stId" : "R-RNO-2395250",
    "displayName" : "LTBP1,LTBP3:TGFB:LAP [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 55147 ],
    "parents" : [ ],
    "children" : [ 10166086, 10166088, 10166090 ]
  }, {
    "dbId" : 10164300,
    "stId" : "R-RNO-2161378",
    "displayName" : "Elastic fibre-asociated proteins [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 55138 ],
    "parents" : [ 10164302 ],
    "children" : [ 10128818, 10164298 ]
  }, {
    "dbId" : 10164291,
    "stId" : "R-RNO-2161303",
    "displayName" : "Emilins [extracellular region]",
    "schemaClass" : "CandidateSet",
    "speciesId" : 48895,
    "diagramIds" : [ 55171 ],
    "parents" : [ 10164293 ],
    "children" : [ 10164273, 10164289, 10164281 ]
  }, {
    "dbId" : 10166082,
    "stId" : "R-RNO-2395241",
    "displayName" : "TGFB3:LAP3 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55158 ],
    "parents" : [ 10166228, 10166090, 10166084 ],
    "children" : [ 10142615, 10166080 ]
  }, {
    "dbId" : 10164289,
    "stId" : "R-RNO-2161347",
    "displayName" : "Emilin-3 polymer [extracellular region]",
    "schemaClass" : "Polymer",
    "speciesId" : 48895,
    "parents" : [ 10164291 ],
    "children" : [ 10164287 ]
  }, {
    "dbId" : 10166080,
    "stId" : "R-RNO-2395290",
    "displayName" : "Tgfb3 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q07258",
    "standardIdentifier" : "uniprot:Q07258",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Tgfb3" ],
    "parents" : [ 10166082 ],
    "children" : [ ]
  }, {
    "dbId" : 10166086,
    "stId" : "R-RNO-9736824",
    "displayName" : "LTBP1,LTBP3:TGFB1:LAP1 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10166092 ],
    "children" : [ 10120047, 10166074 ]
  }, {
    "dbId" : 10164293,
    "stId" : "R-RNO-2396077",
    "displayName" : "Elastic fibre:Fibulins:Emilins [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55139 ],
    "parents" : [ 10164302 ],
    "children" : [ 10164291, 10156541 ]
  }, {
    "dbId" : 10166084,
    "stId" : "R-RNO-2395330",
    "displayName" : "TGFB:LAP [extracellular region]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48895,
    "diagramIds" : [ 55145 ],
    "parents" : [ ],
    "children" : [ 10166082, 10166078, 10120047 ]
  }, {
    "dbId" : 10128753,
    "stId" : "R-RNO-216024",
    "displayName" : "Integrin alphaVbeta6 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10166039, 10166066, 10166226 ],
    "children" : [ 10127831, 10128751 ]
  }, {
    "dbId" : 10125937,
    "stId" : "R-RNO-202730",
    "displayName" : "Integrin alpha5beta1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10166039 ],
    "children" : [ 10123558, 10125935 ]
  }, {
    "dbId" : 10128757,
    "stId" : "R-RNO-2327729",
    "displayName" : "Fibronectin matrix [extracellular region]",
    "schemaClass" : "Polymer",
    "speciesId" : 48895,
    "diagramIds" : [ 55167 ],
    "parents" : [ 10167430 ],
    "children" : [ 10125931 ]
  }, {
    "dbId" : 10125931,
    "stId" : "R-RNO-266103",
    "displayName" : "FN1 dimer [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10128757 ],
    "children" : [ 10125929 ]
  }, {
    "dbId" : 10128744,
    "stId" : "R-RNO-216015",
    "displayName" : "Integrin alphaVbeta1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10166066, 10166226 ],
    "children" : [ 10127831, 10123558 ]
  }, {
    "dbId" : 10125929,
    "stId" : "R-RNO-54851",
    "displayName" : "Fn1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "P04937",
    "standardIdentifier" : "uniprot:P04937",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Fn1" ],
    "parents" : [ 10125931 ],
    "children" : [ ]
  }, {
    "dbId" : 10128751,
    "stId" : "R-RNO-215951",
    "displayName" : "ITGB6 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q6AYF4",
    "standardIdentifier" : "uniprot:Q6AYF4",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10128753 ],
    "children" : [ ]
  }, {
    "dbId" : 10125935,
    "stId" : "R-RNO-202735",
    "displayName" : "ITGA5(42-894) [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "A0A8I5YCC9",
    "standardIdentifier" : "uniprot:A0A8I5YCC9",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10125937 ],
    "children" : [ ]
  }, {
    "dbId" : 10120047,
    "stId" : "R-RNO-2395236",
    "displayName" : "TGFB1:LAP1 [extracellular region]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "diagramIds" : [ 55150 ],
    "parents" : [ 10166070, 10166068, 10166086, 10166084, 10166096 ],
    "children" : [ 10117910, 10120045 ]
  }, {
    "dbId" : 10120045,
    "stId" : "R-RNO-2395367",
    "displayName" : "Tgfb1 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "P17246",
    "standardIdentifier" : "uniprot:P17246",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Tgfb1" ],
    "parents" : [ 10120047 ],
    "children" : [ ]
  }, {
    "dbId" : 10117987,
    "stId" : "R-RNO-114706",
    "displayName" : "Tgfb2 [extracellular region]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "Q07257",
    "standardIdentifier" : "uniprot:Q07257",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Tgfb2" ],
    "parents" : [ 10166078 ],
    "children" : [ ]
  }, {
    "dbId" : 10128742,
    "stId" : "R-RNO-216012",
    "displayName" : "Integrin alpha8beta1 [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48895,
    "parents" : [ 10166066 ],
    "children" : [ 10128740, 10123558 ]
  }, {
    "dbId" : 10128740,
    "stId" : "R-RNO-215943",
    "displayName" : "Itga8 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48895,
    "identifier" : "F7F1E3",
    "standardIdentifier" : "uniprot:F7F1E3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Itga8" ],
    "parents" : [ 10128742 ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 10166043,
    "stId" : "R-RNO-2328037",
    "displayName" : "Fibrillin-1 binds integrins",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10163598 ],
    "inputs" : [ 10166039, 10156525 ],
    "outputs" : [ 10166041 ],
    "efs" : [ ],
    "diagramIds" : [ 55119 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10166267,
    "stId" : "R-RNO-2396399",
    "displayName" : "Fibrillins bind BMPs",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10166263, 10156525 ],
    "outputs" : [ 10166265 ],
    "efs" : [ ],
    "diagramIds" : [ 55160 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10166072,
    "stId" : "R-RNO-2395320",
    "displayName" : "Latent TGF-beta-1 binds integrins",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10166094 ],
    "inputs" : [ 10166068, 10166066 ],
    "outputs" : [ 10166070 ],
    "efs" : [ ],
    "diagramIds" : [ 55152 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10156543,
    "stId" : "R-RNO-1592387",
    "displayName" : "Fibulin binds elastic fibres",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10156521, 10156539 ],
    "outputs" : [ 10156541 ],
    "efs" : [ ],
    "diagramIds" : [ 55141 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10163603,
    "stId" : "R-RNO-2129375",
    "displayName" : "Elastin cross-linking by lysyl oxidase",
    "schemaClass" : "Polymerisation",
    "speciesId" : 0,
    "preceding" : [ 10163589 ],
    "inputs" : [ 10163587 ],
    "outputs" : [ 10156539 ],
    "catalysts" : [ 10163600 ],
    "efs" : [ ],
    "diagramIds" : [ 55134 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10166098,
    "stId" : "R-RNO-2395364",
    "displayName" : "LTBP4 binds TGF-Beta-1",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10166023, 10120047 ],
    "outputs" : [ 10166096 ],
    "efs" : [ ],
    "diagramIds" : [ 55148 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10164306,
    "stId" : "R-RNO-2161293",
    "displayName" : "Tropoelastin forms aggregate globules",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "following" : [ 10163589 ],
    "inputs" : [ 10156345 ],
    "outputs" : [ 10163585 ],
    "efs" : [ ],
    "diagramIds" : [ 55128 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10164304,
    "stId" : "R-RNO-2161282",
    "displayName" : "Elastic fibres bind associated proteins",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10164293, 10164300 ],
    "outputs" : [ 10164302 ],
    "efs" : [ ],
    "diagramIds" : [ 55137 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10166230,
    "stId" : "R-RNO-2396029",
    "displayName" : "Latent TGF-beta-3 binds integrins",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10166226, 10166082 ],
    "outputs" : [ 10166228 ],
    "efs" : [ ],
    "diagramIds" : [ 55156 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10166037,
    "stId" : "R-RNO-2328033",
    "displayName" : "Fibrillin-1 binds latent TGF-beta",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10166033, 10156525 ],
    "outputs" : [ 10166035 ],
    "efs" : [ ],
    "diagramIds" : [ 55163 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10163605,
    "stId" : "R-RNO-2129385",
    "displayName" : "MFAP2, MFAP5 bind microfibrils",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10163598 ],
    "following" : [ 10163589 ],
    "inputs" : [ 10156535, 10156525 ],
    "outputs" : [ 10156537 ],
    "efs" : [ ],
    "diagramIds" : [ 55125 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10167432,
    "stId" : "R-RNO-2537665",
    "displayName" : "Fibulin-1 and -2 bind fibronectin",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10128757, 10156508 ],
    "outputs" : [ 10167430 ],
    "efs" : [ ],
    "diagramIds" : [ 55166 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10166094,
    "stId" : "R-RNO-2395328",
    "displayName" : "LTBP1, LTBP3 bind TGF-Beta",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10166072 ],
    "inputs" : [ 10166084, 10166074 ],
    "outputs" : [ 10166092 ],
    "efs" : [ ],
    "diagramIds" : [ 55144 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10163598,
    "stId" : "R-RNO-2129362",
    "displayName" : "Fibrillin microfibril assembly",
    "schemaClass" : "Polymerisation",
    "speciesId" : 0,
    "preceding" : [ 10163596 ],
    "following" : [ 10163605, 10166043 ],
    "inputs" : [ 10156523 ],
    "outputs" : [ 10156525 ],
    "efs" : [ ],
    "diagramIds" : [ 55123 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10163596,
    "stId" : "R-RNO-2129357",
    "displayName" : "Fibrillin C-terminal processing",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10163598 ],
    "inputs" : [ 10129182 ],
    "outputs" : [ 10163591, 10156523 ],
    "catalysts" : [ 10163593 ],
    "efs" : [ ],
    "diagramIds" : [ 55114 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10163589,
    "stId" : "R-RNO-2129353",
    "displayName" : "Tropoelastin associates with microfibrils",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10163605, 10164306 ],
    "following" : [ 10163603 ],
    "inputs" : [ 10163585, 10156515, 10156537 ],
    "outputs" : [ 10163587 ],
    "efs" : [ ],
    "diagramIds" : [ 55131 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 10224271,
    "stId" : "R-RNO-2129379",
    "displayName" : "Molecules associated with elastic fibres",
    "events" : [ 10166267, 10167432, 10166072, 10156543, 10166094, 10166098, 10164304, 10166230, 10166037 ]
  } ]
}