{
  "dbId" : 11128244,
  "stableId" : "R-PFA-72086",
  "displayName" : "mRNA Capping",
  "nodes" : [ {
    "id" : 50913,
    "reactomeId" : 113571,
    "displayName" : "GTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 302,
      "y" : 406
    },
    "minX" : 282,
    "maxX" : 356,
    "minY" : 390,
    "maxY" : 428,
    "prop" : {
      "x" : 282,
      "y" : 391,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 286,
      "y" : 395
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 317,
          "y" : 396
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 317,
          "y" : 396
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50912,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 325,
          "y" : 414
        },
        "to" : {
          "x" : 356,
          "y" : 428
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 50914,
    "reactomeId" : 111349,
    "displayName" : "GDP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 410,
      "y" : 584
    },
    "minX" : 356,
    "maxX" : 432,
    "minY" : 524,
    "maxY" : 599,
    "prop" : {
      "x" : 390,
      "y" : 569,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 393,
      "y" : 573
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 426,
          "y" : 574
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 426,
          "y" : 574
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50912,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 396,
          "y" : 566
        },
        "to" : {
          "x" : 356,
          "y" : 524
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 388,
          "y" : 564
        },
        "b" : {
          "x" : 396,
          "y" : 566
        },
        "c" : {
          "x" : 394,
          "y" : 558
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 394,
          "y" : 558
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 50915,
    "reactomeId" : 11111068,
    "displayName" : "Capping complex  (intermediate)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 283,
      "y" : 582
    },
    "minX" : 225,
    "maxX" : 356,
    "minY" : 524,
    "maxY" : 660,
    "prop" : {
      "x" : 225,
      "y" : 564,
      "width" : 117,
      "height" : 36
    },
    "textPosition" : {
      "x" : 223,
      "y" : 565
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 342,
          "y" : 564
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 342,
          "y" : 564
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50912,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 305,
          "y" : 561
        },
        "to" : {
          "x" : 356,
          "y" : 524
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 308,
          "y" : 554
        },
        "b" : {
          "x" : 305,
          "y" : 561
        },
        "c" : {
          "x" : 313,
          "y" : 560
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 313,
          "y" : 560
        }
      }
    }, {
      "edgeId" : 50916,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 50916,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 274,
          "y" : 603
        },
        "to" : {
          "x" : 248,
          "y" : 657
        }
      }, {
        "from" : {
          "x" : 248,
          "y" : 657
        },
        "to" : {
          "x" : 265,
          "y" : 656
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 269,
          "y" : 656
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 269,
          "y" : 656
        }
      }
    } ]
  }, {
    "id" : 50917,
    "reactomeId" : 11111073,
    "displayName" : "Capping complex (GpppN..)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 281,
      "y" : 730
    },
    "minX" : 222,
    "maxX" : 347,
    "minY" : 706,
    "maxY" : 748,
    "prop" : {
      "x" : 222,
      "y" : 712,
      "width" : 119,
      "height" : 36
    },
    "textPosition" : {
      "x" : 222,
      "y" : 713
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 341,
          "y" : 712
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 341,
          "y" : 712
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50916,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 50918,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 50919,
    "reactomeId" : 11111078,
    "displayName" : "Capping complex (with freed 5'- GMP)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 284,
      "y" : 869
    },
    "minX" : 219,
    "maxX" : 356,
    "minY" : 845,
    "maxY" : 887,
    "prop" : {
      "x" : 219,
      "y" : 851,
      "width" : 131,
      "height" : 36
    },
    "textPosition" : {
      "x" : 219,
      "y" : 852
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 350,
          "y" : 851
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 350,
          "y" : 851
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50918,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 50921,
    "reactomeId" : 11111031,
    "displayName" : "RNA Pol II with phosphorylated CTD: CE complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 666,
      "y" : 492
    },
    "minX" : 522,
    "maxX" : 730,
    "minY" : 306,
    "maxY" : 524,
    "prop" : {
      "x" : 608,
      "y" : 460,
      "width" : 116,
      "height" : 64
    },
    "textPosition" : {
      "x" : 610,
      "y" : 475
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 724,
          "y" : 460
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 724,
          "y" : 460
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50920,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 641,
          "y" : 457
        },
        "to" : {
          "x" : 522,
          "y" : 306
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 50924,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 50922,
    "reactomeId" : 11111045,
    "displayName" : "RNMT",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 475,
      "y" : 497
    },
    "minX" : 417,
    "maxX" : 539,
    "minY" : 306,
    "maxY" : 515,
    "prop" : {
      "x" : 417,
      "y" : 479,
      "width" : 116,
      "height" : 36
    },
    "textPosition" : {
      "x" : 454,
      "y" : 486
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 533,
          "y" : 479
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 533,
          "y" : 479
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50920,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 479,
          "y" : 476
        },
        "to" : {
          "x" : 522,
          "y" : 306
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 50923,
    "reactomeId" : 11111051,
    "displayName" : "phospho-p-SUPT5H",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 582,
      "y" : 644
    },
    "minX" : 522,
    "maxX" : 623,
    "minY" : 306,
    "maxY" : 655,
    "prop" : {
      "x" : 547,
      "y" : 633,
      "width" : 70,
      "height" : 22
    },
    "textPosition" : {
      "x" : 547,
      "y" : 627
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 617,
          "y" : 633
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 617,
          "y" : 633
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50920,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 580,
          "y" : 630
        },
        "to" : {
          "x" : 522,
          "y" : 306
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 50925,
    "reactomeId" : 11111031,
    "displayName" : "RNA Pol II with phosphorylated CTD: CE complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 853,
      "y" : 492
    },
    "minX" : 797,
    "maxX" : 915,
    "minY" : 461,
    "maxY" : 517,
    "prop" : {
      "x" : 797,
      "y" : 467,
      "width" : 112,
      "height" : 50
    },
    "textPosition" : {
      "x" : 797,
      "y" : 468
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 909,
          "y" : 467
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 909,
          "y" : 467
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50924,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 50905,
    "reactomeId" : 29428,
    "displayName" : "DNA",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 132,
      "y" : 170
    },
    "minX" : 115,
    "maxX" : 166,
    "minY" : 159,
    "maxY" : 205,
    "prop" : {
      "x" : 115,
      "y" : 159,
      "width" : 34,
      "height" : 22
    },
    "textPosition" : {
      "x" : 115,
      "y" : 159
    },
    "connectors" : [ {
      "edgeId" : 50904,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 142,
          "y" : 184
        },
        "to" : {
          "x" : 166,
          "y" : 205
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 50906,
    "reactomeId" : 72084,
    "displayName" : "nascent pre-mRNA transcript",
    "schemaClass" : "OtherEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 179,
      "y" : 260
    },
    "minX" : 118,
    "maxX" : 241,
    "minY" : 205,
    "maxY" : 278,
    "prop" : {
      "x" : 118,
      "y" : 242,
      "width" : 123,
      "height" : 36
    },
    "textPosition" : {
      "x" : 125,
      "y" : 242
    },
    "connectors" : [ {
      "edgeId" : 50904,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 174,
          "y" : 239
        },
        "to" : {
          "x" : 166,
          "y" : 205
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 50907,
    "reactomeId" : 11111053,
    "displayName" : "CE:Pol II CTD:Spt5 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 289,
      "y" : 137
    },
    "minX" : 166,
    "maxX" : 354,
    "minY" : 113,
    "maxY" : 205,
    "prop" : {
      "x" : 231,
      "y" : 119,
      "width" : 117,
      "height" : 36
    },
    "textPosition" : {
      "x" : 243,
      "y" : 120
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 348,
          "y" : 119
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 348,
          "y" : 119
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50920,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 50904,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 256,
          "y" : 158
        },
        "to" : {
          "x" : 166,
          "y" : 205
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 50908,
    "reactomeId" : 11111057,
    "displayName" : "Capping complex (initial)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 337,
      "y" : 207
    },
    "minX" : 281,
    "maxX" : 400,
    "minY" : 183,
    "maxY" : 293,
    "prop" : {
      "x" : 281,
      "y" : 189,
      "width" : 113,
      "height" : 36
    },
    "textPosition" : {
      "x" : 284,
      "y" : 190
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 394,
          "y" : 189
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 394,
          "y" : 189
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50904,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 50909,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 50909,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 342,
          "y" : 228
        },
        "to" : {
          "x" : 361,
          "y" : 292
        }
      }, {
        "from" : {
          "x" : 361,
          "y" : 292
        },
        "to" : {
          "x" : 346,
          "y" : 290
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 342,
          "y" : 289
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 342,
          "y" : 289
        }
      }
    } ]
  }, {
    "id" : 50910,
    "reactomeId" : 113550,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 248,
      "y" : 350
    },
    "minX" : 194,
    "maxX" : 331,
    "minY" : 326,
    "maxY" : 365,
    "prop" : {
      "x" : 194,
      "y" : 335,
      "width" : 109,
      "height" : 30
    },
    "textPosition" : {
      "x" : 239,
      "y" : 339
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 298,
          "y" : 340
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 298,
          "y" : 340
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50909,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 299,
          "y" : 332
        },
        "to" : {
          "x" : 331,
          "y" : 326
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 305,
          "y" : 327
        },
        "b" : {
          "x" : 299,
          "y" : 332
        },
        "c" : {
          "x" : 307,
          "y" : 335
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 307,
          "y" : 335
        }
      }
    } ]
  }, {
    "id" : 50911,
    "reactomeId" : 11111061,
    "displayName" : "Capping complex (hydrolyzed)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 399,
      "y" : 373
    },
    "minX" : 331,
    "maxX" : 465,
    "minY" : 326,
    "maxY" : 477,
    "prop" : {
      "x" : 340,
      "y" : 355,
      "width" : 119,
      "height" : 36
    },
    "textPosition" : {
      "x" : 340,
      "y" : 356
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 459,
          "y" : 355
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 459,
          "y" : 355
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50912,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 384,
          "y" : 394
        },
        "to" : {
          "x" : 356,
          "y" : 428
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 50912,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 398,
          "y" : 394
        },
        "to" : {
          "x" : 398,
          "y" : 474
        }
      }, {
        "from" : {
          "x" : 398,
          "y" : 474
        },
        "to" : {
          "x" : 372,
          "y" : 473
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 368,
          "y" : 473
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 368,
          "y" : 473
        }
      }
    }, {
      "edgeId" : 50909,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 372,
          "y" : 352
        },
        "to" : {
          "x" : 331,
          "y" : 326
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 364,
          "y" : 352
        },
        "b" : {
          "x" : 372,
          "y" : 352
        },
        "c" : {
          "x" : 368,
          "y" : 345
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 368,
          "y" : 345
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 50912,
    "reactomeId" : 11111071,
    "displayName" : "Formation of the CE:GMP intermediate complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 356,
      "y" : 473
    },
    "minX" : 350,
    "maxX" : 362,
    "minY" : 428,
    "maxY" : 524,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 356,
        "y" : 428
      },
      "to" : {
        "x" : 356,
        "y" : 473
      }
    }, {
      "from" : {
        "x" : 356,
        "y" : 473
      },
      "to" : {
        "x" : 356,
        "y" : 524
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 350,
        "y" : 467
      },
      "b" : {
        "x" : 362,
        "y" : 479
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 356,
        "y" : 473
      }
    },
    "inputs" : [ {
      "id" : 50911,
      "points" : [ {
        "x" : 384,
        "y" : 394
      } ]
    }, {
      "id" : 50913,
      "points" : [ {
        "x" : 325,
        "y" : 414
      } ]
    } ],
    "outputs" : [ {
      "id" : 50914,
      "points" : [ {
        "x" : 396,
        "y" : 566
      } ]
    }, {
      "id" : 50915,
      "points" : [ {
        "x" : 305,
        "y" : 561
      } ]
    } ],
    "catalysts" : [ {
      "id" : 50911,
      "points" : [ {
        "x" : 398,
        "y" : 394
      }, {
        "x" : 398,
        "y" : 474
      } ]
    } ]
  }, {
    "id" : 50916,
    "reactomeId" : 11111076,
    "displayName" : "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 281,
      "y" : 656
    },
    "minX" : 275,
    "maxX" : 287,
    "minY" : 603,
    "maxY" : 709,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 282,
        "y" : 603
      },
      "to" : {
        "x" : 281,
        "y" : 656
      }
    }, {
      "from" : {
        "x" : 281,
        "y" : 656
      },
      "to" : {
        "x" : 281,
        "y" : 709
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 277,
        "y" : 702
      },
      "b" : {
        "x" : 281,
        "y" : 709
      },
      "c" : {
        "x" : 285,
        "y" : 702
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 285,
        "y" : 702
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 275,
        "y" : 650
      },
      "b" : {
        "x" : 287,
        "y" : 662
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 281,
        "y" : 656
      }
    },
    "inputs" : [ {
      "id" : 50915
    } ],
    "outputs" : [ {
      "id" : 50917
    } ],
    "catalysts" : [ {
      "id" : 50915,
      "points" : [ {
        "x" : 274,
        "y" : 603
      }, {
        "x" : 248,
        "y" : 657
      } ]
    } ]
  }, {
    "id" : 50918,
    "reactomeId" : 11111080,
    "displayName" : "Dissociation of  transcript with 5'-GMP from GT",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 280,
      "y" : 801
    },
    "minX" : 274,
    "maxX" : 286,
    "minY" : 751,
    "maxY" : 848,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 280,
        "y" : 751
      },
      "to" : {
        "x" : 280,
        "y" : 801
      }
    }, {
      "from" : {
        "x" : 280,
        "y" : 801
      },
      "to" : {
        "x" : 282,
        "y" : 848
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 278,
        "y" : 841
      },
      "b" : {
        "x" : 282,
        "y" : 848
      },
      "c" : {
        "x" : 286,
        "y" : 841
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 286,
        "y" : 841
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 274,
        "y" : 795
      },
      "b" : {
        "x" : 286,
        "y" : 807
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 280,
        "y" : 801
      }
    },
    "inputs" : [ {
      "id" : 50917
    } ],
    "outputs" : [ {
      "id" : 50919
    } ]
  }, {
    "id" : 50920,
    "reactomeId" : 11111055,
    "displayName" : "SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 559,
      "y" : 136
    },
    "minX" : 351,
    "maxX" : 565,
    "minY" : 130,
    "maxY" : 306,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 522,
        "y" : 306
      },
      "to" : {
        "x" : 559,
        "y" : 136
      }
    }, {
      "from" : {
        "x" : 559,
        "y" : 136
      },
      "to" : {
        "x" : 351,
        "y" : 136
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 358,
        "y" : 132
      },
      "b" : {
        "x" : 351,
        "y" : 136
      },
      "c" : {
        "x" : 358,
        "y" : 140
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 358,
        "y" : 140
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 559,
        "y" : 136
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 559,
        "y" : 136
      }
    },
    "inputs" : [ {
      "id" : 50921,
      "points" : [ {
        "x" : 641,
        "y" : 457
      } ]
    }, {
      "id" : 50922,
      "points" : [ {
        "x" : 479,
        "y" : 476
      } ]
    }, {
      "id" : 50923,
      "points" : [ {
        "x" : 580,
        "y" : 630
      } ]
    } ],
    "outputs" : [ {
      "id" : 50907
    } ]
  }, {
    "id" : 50904,
    "reactomeId" : 11111059,
    "displayName" : "Capping complex formation",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 232,
      "y" : 205
    },
    "minX" : 166,
    "maxX" : 278,
    "minY" : 199,
    "maxY" : 211,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 166,
        "y" : 205
      },
      "to" : {
        "x" : 232,
        "y" : 205
      }
    }, {
      "from" : {
        "x" : 232,
        "y" : 205
      },
      "to" : {
        "x" : 278,
        "y" : 205
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 271,
        "y" : 209
      },
      "b" : {
        "x" : 278,
        "y" : 205
      },
      "c" : {
        "x" : 271,
        "y" : 201
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 271,
        "y" : 201
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 232,
        "y" : 205
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 232,
        "y" : 205
      }
    },
    "inputs" : [ {
      "id" : 50905,
      "points" : [ {
        "x" : 142,
        "y" : 184
      } ]
    }, {
      "id" : 50906,
      "points" : [ {
        "x" : 174,
        "y" : 239
      } ]
    }, {
      "id" : 50907,
      "points" : [ {
        "x" : 256,
        "y" : 158
      } ]
    } ],
    "outputs" : [ {
      "id" : 50908
    } ]
  }, {
    "id" : 50924,
    "reactomeId" : 11111033,
    "displayName" : "Activation of GT",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 773,
      "y" : 492
    },
    "minX" : 727,
    "maxX" : 794,
    "minY" : 486,
    "maxY" : 498,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 794,
        "y" : 492
      },
      "to" : {
        "x" : 773,
        "y" : 492
      }
    }, {
      "from" : {
        "x" : 773,
        "y" : 492
      },
      "to" : {
        "x" : 727,
        "y" : 492
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 734,
        "y" : 488
      },
      "b" : {
        "x" : 727,
        "y" : 492
      },
      "c" : {
        "x" : 734,
        "y" : 496
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 734,
        "y" : 496
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 767,
        "y" : 486
      },
      "b" : {
        "x" : 779,
        "y" : 498
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 773,
        "y" : 492
      }
    },
    "inputs" : [ {
      "id" : 50925
    } ],
    "outputs" : [ {
      "id" : 50921
    } ]
  }, {
    "id" : 50909,
    "reactomeId" : 11111064,
    "displayName" : "Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 330,
      "y" : 287
    },
    "minX" : 324,
    "maxX" : 336,
    "minY" : 228,
    "maxY" : 326,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 335,
        "y" : 228
      },
      "to" : {
        "x" : 330,
        "y" : 287
      }
    }, {
      "from" : {
        "x" : 330,
        "y" : 287
      },
      "to" : {
        "x" : 331,
        "y" : 326
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 324,
        "y" : 281
      },
      "b" : {
        "x" : 336,
        "y" : 293
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 330,
        "y" : 287
      }
    },
    "inputs" : [ {
      "id" : 50908
    } ],
    "outputs" : [ {
      "id" : 50910,
      "points" : [ {
        "x" : 299,
        "y" : 332
      } ]
    }, {
      "id" : 50911,
      "points" : [ {
        "x" : 372,
        "y" : 352
      } ]
    } ],
    "catalysts" : [ {
      "id" : 50908,
      "points" : [ {
        "x" : 342,
        "y" : 228
      }, {
        "x" : 361,
        "y" : 292
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 50926,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 799,
      "y" : 550
    },
    "minX" : 0,
    "maxX" : 1598,
    "minY" : 0,
    "maxY" : 1100,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 1598,
      "height" : 1100
    },
    "textPosition" : {
      "x" : 19,
      "y" : 1063
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 1578,
      "height" : 1080
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 50927 ]
  }, {
    "id" : 50927,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 793,
      "y" : 544
    },
    "minX" : 38,
    "maxX" : 1548,
    "minY" : 34,
    "maxY" : 1054,
    "prop" : {
      "x" : 38,
      "y" : 34,
      "width" : 1510,
      "height" : 1020
    },
    "textPosition" : {
      "x" : 56,
      "y" : 1013
    },
    "insets" : {
      "x" : 48,
      "y" : 44,
      "width" : 1490,
      "height" : 1000
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 50904, 50906, 50907, 50908, 50905, 50909, 50910, 50911, 50912, 50913, 50914, 50915, 50916, 50917, 50918, 50919, 50920, 50922, 50921, 50924, 50925, 50923 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 1598,
  "minY" : 0,
  "maxY" : 1100,
  "disease" : false
}