{
  "dbId" : 10100337,
  "stableId" : "R-MMU-5632684",
  "displayName" : "Hedgehog 'on' state",
  "nodes" : [ {
    "id" : 65665,
    "reactomeId" : 10020627,
    "displayName" : "Itch",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2165,
      "y" : 1195
    },
    "minX" : 2138,
    "maxX" : 2214,
    "minY" : 1178,
    "maxY" : 1225,
    "prop" : {
      "x" : 2138,
      "y" : 1184,
      "width" : 54,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2149,
      "y" : 1184
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2192,
          "y" : 1184
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2192,
          "y" : 1184
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65663,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2182,
          "y" : 1209
        },
        "to" : {
          "x" : 2214,
          "y" : 1225
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65664,
    "reactomeId" : 10017251,
    "displayName" : "Numb",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2239,
      "y" : 1193
    },
    "minX" : 2214,
    "maxX" : 2268,
    "minY" : 1176,
    "maxY" : 1225,
    "prop" : {
      "x" : 2217,
      "y" : 1182,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2217,
      "y" : 1182
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2262,
          "y" : 1182
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2262,
          "y" : 1182
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65663,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2230,
          "y" : 1207
        },
        "to" : {
          "x" : 2214,
          "y" : 1225
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65666,
    "reactomeId" : 10055715,
    "displayName" : "NUMB:ITCH",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2223,
      "y" : 1298
    },
    "minX" : 2185,
    "maxX" : 2413,
    "minY" : 1255,
    "maxY" : 1381,
    "prop" : {
      "x" : 2185,
      "y" : 1287,
      "width" : 76,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2185,
      "y" : 1288
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2261,
          "y" : 1287
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2261,
          "y" : 1287
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65667,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2223,
          "y" : 1312
        },
        "to" : {
          "x" : 2230,
          "y" : 1381
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65673,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2264,
          "y" : 1289
        },
        "to" : {
          "x" : 2413,
          "y" : 1255
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2270,
          "y" : 1284
        },
        "b" : {
          "x" : 2264,
          "y" : 1289
        },
        "c" : {
          "x" : 2272,
          "y" : 1291
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2272,
          "y" : 1291
        }
      }
    }, {
      "edgeId" : 65663,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65669,
    "reactomeId" : 10057425,
    "displayName" : "GLI1:NUMB:ITCH",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2337,
      "y" : 1386
    },
    "minX" : 2296,
    "maxX" : 2413,
    "minY" : 1364,
    "maxY" : 1427,
    "prop" : {
      "x" : 2296,
      "y" : 1370,
      "width" : 83,
      "height" : 33
    },
    "textPosition" : {
      "x" : 2298,
      "y" : 1368
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2379,
          "y" : 1370
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2379,
          "y" : 1370
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65667,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65670,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2382,
          "y" : 1387
        },
        "to" : {
          "x" : 2398,
          "y" : 1388
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65670,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2353,
          "y" : 1406
        },
        "to" : {
          "x" : 2377,
          "y" : 1427
        }
      }, {
        "from" : {
          "x" : 2377,
          "y" : 1427
        },
        "to" : {
          "x" : 2406,
          "y" : 1399
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2409,
          "y" : 1396
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2409,
          "y" : 1396
        }
      }
    } ]
  }, {
    "id" : 65668,
    "reactomeId" : 10055598,
    "displayName" : "Gli1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2159,
      "y" : 1381
    },
    "minX" : 2123,
    "maxX" : 2230,
    "minY" : 1360,
    "maxY" : 1396,
    "prop" : {
      "x" : 2123,
      "y" : 1366,
      "width" : 72,
      "height" : 30
    },
    "textPosition" : {
      "x" : 2143,
      "y" : 1370
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2195,
          "y" : 1366
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2195,
          "y" : 1366
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65667,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2198,
          "y" : 1381
        },
        "to" : {
          "x" : 2230,
          "y" : 1381
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65671,
    "reactomeId" : 9985374,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2363,
      "y" : 1324
    },
    "minX" : 2330,
    "maxX" : 2413,
    "minY" : 1255,
    "maxY" : 1388,
    "prop" : {
      "x" : 2330,
      "y" : 1307,
      "width" : 67,
      "height" : 34
    },
    "textPosition" : {
      "x" : 2351,
      "y" : 1313
    },
    "connectors" : [ {
      "edgeId" : 65670,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2372,
          "y" : 1347
        },
        "to" : {
          "x" : 2398,
          "y" : 1388
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65673,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2375,
          "y" : 1301
        },
        "to" : {
          "x" : 2413,
          "y" : 1255
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2376,
          "y" : 1293
        },
        "b" : {
          "x" : 2375,
          "y" : 1301
        },
        "c" : {
          "x" : 2382,
          "y" : 1298
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2382,
          "y" : 1298
        }
      }
    } ]
  }, {
    "id" : 65672,
    "reactomeId" : 10057431,
    "displayName" : "ub-GLI1:NUMB:ITCH",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2493,
      "y" : 1384
    },
    "minX" : 2446,
    "maxX" : 2547,
    "minY" : 1356,
    "maxY" : 1407,
    "prop" : {
      "x" : 2446,
      "y" : 1362,
      "width" : 95,
      "height" : 45
    },
    "textPosition" : {
      "x" : 2456,
      "y" : 1372
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2541,
          "y" : 1362
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2541,
          "y" : 1362
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65670,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65673,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65674,
    "reactomeId" : 9985422,
    "displayName" : "26S proteasome",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2491,
      "y" : 1212
    },
    "minX" : 2447,
    "maxX" : 2542,
    "minY" : 1189,
    "maxY" : 1261,
    "prop" : {
      "x" : 2447,
      "y" : 1195,
      "width" : 89,
      "height" : 35
    },
    "textPosition" : {
      "x" : 2449,
      "y" : 1195
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2536,
          "y" : 1195
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2536,
          "y" : 1195
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65673,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2492,
          "y" : 1233
        },
        "to" : {
          "x" : 2494,
          "y" : 1253
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2494,
          "y" : 1257
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2494,
          "y" : 1257
        }
      }
    } ]
  }, {
    "id" : 65689,
    "reactomeId" : 10057341,
    "displayName" : "phospho-Gli1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1493,
      "y" : 1522
    },
    "minX" : 1462,
    "maxX" : 1531,
    "minY" : 1500,
    "maxY" : 1539,
    "prop" : {
      "x" : 1462,
      "y" : 1506,
      "width" : 63,
      "height" : 33
    },
    "textPosition" : {
      "x" : 1462,
      "y" : 1505
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1525,
          "y" : 1506
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1525,
          "y" : 1506
        }
      }
    },
    "connectors" : [ ]
  }, {
    "id" : 65599,
    "reactomeId" : 10055775,
    "displayName" : "SMO dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 940,
      "y" : 1271
    },
    "minX" : 888,
    "maxX" : 998,
    "minY" : 1251,
    "maxY" : 1286,
    "prop" : {
      "x" : 888,
      "y" : 1257,
      "width" : 104,
      "height" : 29
    },
    "textPosition" : {
      "x" : 903,
      "y" : 1265
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 992,
          "y" : 1257
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 992,
          "y" : 1257
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65598,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65601,
    "reactomeId" : 10057205,
    "displayName" : "SMO dimer:ARRB:KIF3A",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 630,
      "y" : 1274
    },
    "minX" : 569,
    "maxX" : 745,
    "minY" : 1074,
    "maxY" : 1292,
    "prop" : {
      "x" : 569,
      "y" : 1256,
      "width" : 122,
      "height" : 36
    },
    "textPosition" : {
      "x" : 573,
      "y" : 1257
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 691,
          "y" : 1256
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 691,
          "y" : 1256
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65598,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 640,
          "y" : 1253
        },
        "to" : {
          "x" : 745,
          "y" : 1074
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 745,
          "y" : 1082
        },
        "b" : {
          "x" : 745,
          "y" : 1074
        },
        "c" : {
          "x" : 738,
          "y" : 1078
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 738,
          "y" : 1078
        }
      }
    } ]
  }, {
    "id" : 65600,
    "reactomeId" : 10057201,
    "displayName" : "SMO dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 613,
      "y" : 950
    },
    "minX" : 567,
    "maxX" : 665,
    "minY" : 929,
    "maxY" : 966,
    "prop" : {
      "x" : 567,
      "y" : 935,
      "width" : 92,
      "height" : 31
    },
    "textPosition" : {
      "x" : 576,
      "y" : 945
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 659,
          "y" : 935
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 659,
          "y" : 935
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65598,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65603,
    "reactomeId" : 10057197,
    "displayName" : "Hh-Npp:CDON:PTCH",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 430,
      "y" : 511
    },
    "minX" : 388,
    "maxX" : 741,
    "minY" : 487,
    "maxY" : 1100,
    "prop" : {
      "x" : 388,
      "y" : 493,
      "width" : 84,
      "height" : 37
    },
    "textPosition" : {
      "x" : 390,
      "y" : 495
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 472,
          "y" : 493
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 472,
          "y" : 493
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65606,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65598,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 447,
          "y" : 533
        },
        "to" : {
          "x" : 511,
          "y" : 599
        }
      }, {
        "from" : {
          "x" : 511,
          "y" : 599
        },
        "to" : {
          "x" : 550,
          "y" : 1100
        }
      }, {
        "from" : {
          "x" : 550,
          "y" : 1100
        },
        "to" : {
          "x" : 741,
          "y" : 1068
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 735,
          "y" : 1073
        },
        "b" : {
          "x" : 741,
          "y" : 1068
        },
        "c" : {
          "x" : 734,
          "y" : 1065
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 734,
          "y" : 1065
        }
      }
    } ]
  }, {
    "id" : 65602,
    "reactomeId" : 10057209,
    "displayName" : "Hh-Npp:BOC:PTCH1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 429,
      "y" : 213
    },
    "minX" : 390,
    "maxX" : 741,
    "minY" : 180,
    "maxY" : 1070,
    "prop" : {
      "x" : 390,
      "y" : 186,
      "width" : 78,
      "height" : 54
    },
    "textPosition" : {
      "x" : 390,
      "y" : 205
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 468,
          "y" : 186
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 468,
          "y" : 186
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65598,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 443,
          "y" : 243
        },
        "to" : {
          "x" : 518,
          "y" : 377
        }
      }, {
        "from" : {
          "x" : 518,
          "y" : 377
        },
        "to" : {
          "x" : 565,
          "y" : 1066
        }
      }, {
        "from" : {
          "x" : 565,
          "y" : 1066
        },
        "to" : {
          "x" : 741,
          "y" : 1066
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 734,
          "y" : 1070
        },
        "b" : {
          "x" : 741,
          "y" : 1066
        },
        "c" : {
          "x" : 734,
          "y" : 1062
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 734,
          "y" : 1062
        }
      }
    } ]
  }, {
    "id" : 65605,
    "reactomeId" : 10057213,
    "displayName" : "Drc4",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 849,
      "y" : 1061
    },
    "minX" : 759,
    "maxX" : 889,
    "minY" : 1040,
    "maxY" : 1076,
    "prop" : {
      "x" : 815,
      "y" : 1046,
      "width" : 68,
      "height" : 30
    },
    "textPosition" : {
      "x" : 830,
      "y" : 1050
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 883,
          "y" : 1046
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 883,
          "y" : 1046
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65598,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 812,
          "y" : 1062
        },
        "to" : {
          "x" : 759,
          "y" : 1065
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 766,
          "y" : 1061
        },
        "b" : {
          "x" : 759,
          "y" : 1065
        },
        "c" : {
          "x" : 766,
          "y" : 1069
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 766,
          "y" : 1069
        }
      }
    } ]
  }, {
    "id" : 65604,
    "reactomeId" : 10057193,
    "displayName" : "Hh-Npp:GAS1:PTCH",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 414,
      "y" : 365
    },
    "minX" : 371,
    "maxX" : 741,
    "minY" : 337,
    "maxY" : 1085,
    "prop" : {
      "x" : 371,
      "y" : 343,
      "width" : 86,
      "height" : 45
    },
    "textPosition" : {
      "x" : 375,
      "y" : 353
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 457,
          "y" : 343
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 457,
          "y" : 343
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65610,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65598,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 430,
          "y" : 391
        },
        "to" : {
          "x" : 512,
          "y" : 499
        }
      }, {
        "from" : {
          "x" : 512,
          "y" : 499
        },
        "to" : {
          "x" : 558,
          "y" : 1085
        }
      }, {
        "from" : {
          "x" : 558,
          "y" : 1085
        },
        "to" : {
          "x" : 741,
          "y" : 1067
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 734,
          "y" : 1072
        },
        "b" : {
          "x" : 741,
          "y" : 1067
        },
        "c" : {
          "x" : 734,
          "y" : 1064
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 734,
          "y" : 1064
        }
      }
    } ]
  }, {
    "id" : 65607,
    "reactomeId" : 10009241,
    "displayName" : "Cdon",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 421,
      "y" : 588
    },
    "minX" : 334,
    "maxX" : 454,
    "minY" : 562,
    "maxY" : 600,
    "prop" : {
      "x" : 394,
      "y" : 577,
      "width" : 54,
      "height" : 23
    },
    "textPosition" : {
      "x" : 401,
      "y" : 578
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 448,
          "y" : 577
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 448,
          "y" : 577
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65606,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 391,
          "y" : 579
        },
        "to" : {
          "x" : 334,
          "y" : 562
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65609,
    "reactomeId" : 10055782,
    "displayName" : "Ptch1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 407,
      "y" : 638
    },
    "minX" : 284,
    "maxX" : 450,
    "minY" : 392,
    "maxY" : 652,
    "prop" : {
      "x" : 370,
      "y" : 625,
      "width" : 74,
      "height" : 27
    },
    "textPosition" : {
      "x" : 385,
      "y" : 628
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 444,
          "y" : 625
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 444,
          "y" : 625
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65606,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 394,
          "y" : 622
        },
        "to" : {
          "x" : 334,
          "y" : 562
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65610,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 384,
          "y" : 622
        },
        "to" : {
          "x" : 284,
          "y" : 563
        }
      }, {
        "from" : {
          "x" : 284,
          "y" : 563
        },
        "to" : {
          "x" : 309,
          "y" : 392
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65608,
    "reactomeId" : 10017511,
    "displayName" : "Hh-Npp",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 30,
      "y" : 609
    },
    "minX" : 0,
    "maxX" : 334,
    "minY" : 95,
    "maxY" : 620,
    "prop" : {
      "x" : 0,
      "y" : 598,
      "width" : 61,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3,
      "y" : 598
    },
    "connectors" : [ {
      "edgeId" : 65606,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 67,
          "y" : 604
        },
        "to" : {
          "x" : 334,
          "y" : 562
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65610,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 44,
          "y" : 592
        },
        "to" : {
          "x" : 309,
          "y" : 392
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65620,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 35,
          "y" : 592
        },
        "to" : {
          "x" : 291,
          "y" : 95
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65611,
    "reactomeId" : 10057191,
    "displayName" : "Gas1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 414,
      "y" : 444
    },
    "minX" : 309,
    "maxX" : 449,
    "minY" : 392,
    "maxY" : 460,
    "prop" : {
      "x" : 385,
      "y" : 428,
      "width" : 58,
      "height" : 32
    },
    "textPosition" : {
      "x" : 394,
      "y" : 433
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 443,
          "y" : 428
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 443,
          "y" : 428
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65610,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 382,
          "y" : 429
        },
        "to" : {
          "x" : 309,
          "y" : 392
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65613,
    "reactomeId" : 10057222,
    "displayName" : "Ptch1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 417,
      "y" : 976
    },
    "minX" : 387,
    "maxX" : 453,
    "minY" : 921,
    "maxY" : 993,
    "prop" : {
      "x" : 387,
      "y" : 959,
      "width" : 60,
      "height" : 34
    },
    "textPosition" : {
      "x" : 395,
      "y" : 965
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 447,
          "y" : 959
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 447,
          "y" : 959
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65637,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 415,
          "y" : 956
        },
        "to" : {
          "x" : 411,
          "y" : 921
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 410,
          "y" : 950
        },
        "b" : {
          "x" : 415,
          "y" : 956
        },
        "c" : {
          "x" : 418,
          "y" : 949
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 418,
          "y" : 949
        }
      }
    }, {
      "edgeId" : 65612,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65614,
    "reactomeId" : 10057224,
    "displayName" : "Ptch1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 433,
      "y" : 1320
    },
    "minX" : 401,
    "maxX" : 472,
    "minY" : 1295,
    "maxY" : 1340,
    "prop" : {
      "x" : 401,
      "y" : 1301,
      "width" : 65,
      "height" : 39
    },
    "textPosition" : {
      "x" : 411,
      "y" : 1310
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 466,
          "y" : 1301
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 466,
          "y" : 1301
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65612,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65617,
    "reactomeId" : 5632506,
    "displayName" : "Csnk1a1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 720,
      "y" : 930
    },
    "minX" : 599,
    "maxX" : 848,
    "minY" : 329,
    "maxY" : 943,
    "prop" : {
      "x" : 676,
      "y" : 917,
      "width" : 88,
      "height" : 26
    },
    "textPosition" : {
      "x" : 689,
      "y" : 919
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 764,
          "y" : 917
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 764,
          "y" : 917
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65615,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 723,
          "y" : 914
        },
        "to" : {
          "x" : 848,
          "y" : 484
        }
      }, {
        "from" : {
          "x" : 848,
          "y" : 484
        },
        "to" : {
          "x" : 599,
          "y" : 329
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 721,
          "y" : 906
        },
        "b" : {
          "x" : 723,
          "y" : 914
        },
        "c" : {
          "x" : 729,
          "y" : 908
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 729,
          "y" : 908
        }
      }
    } ]
  }, {
    "id" : 65616,
    "reactomeId" : 10057251,
    "displayName" : "p6S, T-SMO dimer:CSNK1A1:ADRBK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 605,
      "y" : 401
    },
    "minX" : 545,
    "maxX" : 672,
    "minY" : 377,
    "maxY" : 419,
    "prop" : {
      "x" : 545,
      "y" : 383,
      "width" : 121,
      "height" : 36
    },
    "textPosition" : {
      "x" : 545,
      "y" : 384
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 666,
          "y" : 383
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 666,
          "y" : 383
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65615,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65619,
    "reactomeId" : 5632501,
    "displayName" : "Adrbk1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 729,
      "y" : 638
    },
    "minX" : 599,
    "maxX" : 803,
    "minY" : 329,
    "maxY" : 649,
    "prop" : {
      "x" : 701,
      "y" : 627,
      "width" : 57,
      "height" : 22
    },
    "textPosition" : {
      "x" : 703,
      "y" : 627
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 758,
          "y" : 627
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 758,
          "y" : 627
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65615,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 734,
          "y" : 624
        },
        "to" : {
          "x" : 803,
          "y" : 491
        }
      }, {
        "from" : {
          "x" : 803,
          "y" : 491
        },
        "to" : {
          "x" : 599,
          "y" : 329
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 734,
          "y" : 616
        },
        "b" : {
          "x" : 734,
          "y" : 624
        },
        "c" : {
          "x" : 741,
          "y" : 620
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 741,
          "y" : 620
        }
      }
    } ]
  }, {
    "id" : 65618,
    "reactomeId" : 10057249,
    "displayName" : "p6S, T-SMO dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 598,
      "y" : 293
    },
    "minX" : 540,
    "maxX" : 663,
    "minY" : 276,
    "maxY" : 329,
    "prop" : {
      "x" : 540,
      "y" : 282,
      "width" : 117,
      "height" : 22
    },
    "textPosition" : {
      "x" : 540,
      "y" : 283
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 657,
          "y" : 282
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 657,
          "y" : 282
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65615,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 598,
          "y" : 307
        },
        "to" : {
          "x" : 599,
          "y" : 329
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 602,
          "y" : 314
        },
        "b" : {
          "x" : 598,
          "y" : 307
        },
        "c" : {
          "x" : 594,
          "y" : 314
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 594,
          "y" : 314
        }
      }
    } ]
  }, {
    "id" : 65621,
    "reactomeId" : 10017504,
    "displayName" : "HHIP",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 417,
      "y" : 32
    },
    "minX" : 291,
    "maxX" : 442,
    "minY" : 15,
    "maxY" : 95,
    "prop" : {
      "x" : 399,
      "y" : 21,
      "width" : 37,
      "height" : 22
    },
    "textPosition" : {
      "x" : 399,
      "y" : 21
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 436,
          "y" : 21
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 436,
          "y" : 21
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65620,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 396,
          "y" : 41
        },
        "to" : {
          "x" : 291,
          "y" : 95
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65622,
    "reactomeId" : 10017513,
    "displayName" : "Hh-Npp:HHIP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 420,
      "y" : 117
    },
    "minX" : 380,
    "maxX" : 466,
    "minY" : 94,
    "maxY" : 135,
    "prop" : {
      "x" : 380,
      "y" : 100,
      "width" : 80,
      "height" : 35
    },
    "textPosition" : {
      "x" : 391,
      "y" : 100
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 460,
          "y" : 100
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 460,
          "y" : 100
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65620,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65625,
    "reactomeId" : 10055605,
    "displayName" : "GLI1,2,3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1000,
      "y" : 1118
    },
    "minX" : 959,
    "maxX" : 1047,
    "minY" : 1089,
    "maxY" : 1130,
    "prop" : {
      "x" : 959,
      "y" : 1106,
      "width" : 82,
      "height" : 24
    },
    "textPosition" : {
      "x" : 971,
      "y" : 1107
    },
    "connectors" : [ {
      "edgeId" : 65623,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1019,
          "y" : 1100
        },
        "to" : {
          "x" : 1047,
          "y" : 1089
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65624,
    "reactomeId" : 5610427,
    "displayName" : "Sufu",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 997,
      "y" : 1059
    },
    "minX" : 966,
    "maxX" : 1047,
    "minY" : 1039,
    "maxY" : 1089,
    "prop" : {
      "x" : 966,
      "y" : 1045,
      "width" : 62,
      "height" : 28
    },
    "textPosition" : {
      "x" : 979,
      "y" : 1048
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1028,
          "y" : 1045
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1028,
          "y" : 1045
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65623,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1020,
          "y" : 1076
        },
        "to" : {
          "x" : 1047,
          "y" : 1089
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65626,
    "reactomeId" : 10055607,
    "displayName" : "GLI:SUFU",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1158,
      "y" : 1091
    },
    "minX" : 1123,
    "maxX" : 1200,
    "minY" : 1072,
    "maxY" : 1104,
    "prop" : {
      "x" : 1123,
      "y" : 1078,
      "width" : 71,
      "height" : 26
    },
    "textPosition" : {
      "x" : 1127,
      "y" : 1083
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1194,
          "y" : 1078
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1194,
          "y" : 1078
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65623,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65627,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65629,
    "reactomeId" : 10055709,
    "displayName" : "KIF7",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1035,
      "y" : 835
    },
    "minX" : 1010,
    "maxX" : 1159,
    "minY" : 814,
    "maxY" : 850,
    "prop" : {
      "x" : 1010,
      "y" : 820,
      "width" : 50,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1018,
      "y" : 824
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1060,
          "y" : 820
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1060,
          "y" : 820
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65627,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 1063,
          "y" : 833
        },
        "to" : {
          "x" : 1159,
          "y" : 827
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1152,
          "y" : 831
        },
        "b" : {
          "x" : 1159,
          "y" : 827
        },
        "c" : {
          "x" : 1152,
          "y" : 823
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 1152,
          "y" : 823
        }
      }
    } ]
  }, {
    "id" : 65628,
    "reactomeId" : 10055797,
    "displayName" : "GLI:SUFU",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1138,
      "y" : 322
    },
    "minX" : 1106,
    "maxX" : 1176,
    "minY" : 305,
    "maxY" : 333,
    "prop" : {
      "x" : 1106,
      "y" : 311,
      "width" : 64,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1106,
      "y" : 312
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1170,
          "y" : 311
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1170,
          "y" : 311
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65627,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65630,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65631,
    "reactomeId" : 10055793,
    "displayName" : "GLI1,2,3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1175,
      "y" : 199
    },
    "minX" : 1138,
    "maxX" : 1253,
    "minY" : 187,
    "maxY" : 257,
    "prop" : {
      "x" : 1138,
      "y" : 187,
      "width" : 74,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1146,
      "y" : 189
    },
    "connectors" : [ {
      "edgeId" : 65643,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1218,
          "y" : 198
        },
        "to" : {
          "x" : 1253,
          "y" : 197
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65630,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1167,
          "y" : 218
        },
        "to" : {
          "x" : 1139,
          "y" : 257
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1166,
          "y" : 226
        },
        "b" : {
          "x" : 1167,
          "y" : 218
        },
        "c" : {
          "x" : 1160,
          "y" : 221
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1160,
          "y" : 221
        }
      }
    } ]
  }, {
    "id" : 65633,
    "reactomeId" : 10057417,
    "displayName" : "p6S, T-SMO dimer:EVC2:EVC",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 628,
      "y" : 211
    },
    "minX" : 568,
    "maxX" : 1130,
    "minY" : 187,
    "maxY" : 285,
    "prop" : {
      "x" : 568,
      "y" : 193,
      "width" : 121,
      "height" : 36
    },
    "textPosition" : {
      "x" : 568,
      "y" : 194
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 689,
          "y" : 193
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 689,
          "y" : 193
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65630,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 692,
          "y" : 219
        },
        "to" : {
          "x" : 1130,
          "y" : 282
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1123,
          "y" : 285
        },
        "b" : {
          "x" : 1130,
          "y" : 282
        },
        "c" : {
          "x" : 1124,
          "y" : 277
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 1124,
          "y" : 277
        }
      }
    } ]
  }, {
    "id" : 65632,
    "reactomeId" : 10055795,
    "displayName" : "Sufu",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1100,
      "y" : 210
    },
    "minX" : 1075,
    "maxX" : 1139,
    "minY" : 113,
    "maxY" : 257,
    "prop" : {
      "x" : 1079,
      "y" : 199,
      "width" : 42,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1082,
      "y" : 199
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1121,
          "y" : 199
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1121,
          "y" : 199
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65640,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1097,
          "y" : 196
        },
        "to" : {
          "x" : 1075,
          "y" : 113
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1091,
          "y" : 190
        },
        "b" : {
          "x" : 1097,
          "y" : 196
        },
        "c" : {
          "x" : 1099,
          "y" : 188
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1099,
          "y" : 188
        }
      }
    }, {
      "edgeId" : 65630,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1109,
          "y" : 224
        },
        "to" : {
          "x" : 1139,
          "y" : 257
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1117,
          "y" : 226
        },
        "b" : {
          "x" : 1109,
          "y" : 224
        },
        "c" : {
          "x" : 1111,
          "y" : 232
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1111,
          "y" : 232
        }
      }
    } ]
  }, {
    "id" : 65635,
    "reactomeId" : 10057355,
    "displayName" : "p-GLI1,2,3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1295,
      "y" : 321
    },
    "minX" : 1235,
    "maxX" : 1355,
    "minY" : 228,
    "maxY" : 339,
    "prop" : {
      "x" : 1235,
      "y" : 303,
      "width" : 120,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1260,
      "y" : 310
    },
    "connectors" : [ {
      "edgeId" : 65634,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65643,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1294,
          "y" : 297
        },
        "to" : {
          "x" : 1291,
          "y" : 228
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1290,
          "y" : 290
        },
        "b" : {
          "x" : 1294,
          "y" : 297
        },
        "c" : {
          "x" : 1298,
          "y" : 290
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1298,
          "y" : 290
        }
      }
    } ]
  }, {
    "id" : 65636,
    "reactomeId" : 10057339,
    "displayName" : "p-GLI1,2,3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1385,
      "y" : 1260
    },
    "minX" : 1342,
    "maxX" : 1428,
    "minY" : 1246,
    "maxY" : 1274,
    "prop" : {
      "x" : 1342,
      "y" : 1246,
      "width" : 86,
      "height" : 28
    },
    "textPosition" : {
      "x" : 1350,
      "y" : 1249
    },
    "connectors" : [ {
      "edgeId" : 65634,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65639,
    "reactomeId" : 10003661,
    "displayName" : "SMURF",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 186,
      "y" : 1048
    },
    "minX" : 161,
    "maxX" : 411,
    "minY" : 921,
    "maxY" : 1127,
    "prop" : {
      "x" : 161,
      "y" : 1037,
      "width" : 51,
      "height" : 22
    },
    "textPosition" : {
      "x" : 161,
      "y" : 1037
    },
    "connectors" : [ {
      "edgeId" : 65637,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 202,
          "y" : 1065
        },
        "to" : {
          "x" : 305,
          "y" : 1127
        }
      }, {
        "from" : {
          "x" : 305,
          "y" : 1127
        },
        "to" : {
          "x" : 379,
          "y" : 949
        }
      }, {
        "from" : {
          "x" : 379,
          "y" : 949
        },
        "to" : {
          "x" : 411,
          "y" : 921
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 210,
          "y" : 1065
        },
        "b" : {
          "x" : 202,
          "y" : 1065
        },
        "c" : {
          "x" : 206,
          "y" : 1072
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 206,
          "y" : 1072
        }
      }
    } ]
  }, {
    "id" : 65638,
    "reactomeId" : 10057436,
    "displayName" : "ub-PTCH1:SMURF",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 420,
      "y" : 865
    },
    "minX" : 378,
    "maxX" : 469,
    "minY" : 841,
    "maxY" : 884,
    "prop" : {
      "x" : 378,
      "y" : 847,
      "width" : 85,
      "height" : 37
    },
    "textPosition" : {
      "x" : 384,
      "y" : 849
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 463,
          "y" : 847
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 463,
          "y" : 847
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65637,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65641,
    "reactomeId" : 10057326,
    "displayName" : "ULK3:SUFU",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 974,
      "y" : 61
    },
    "minX" : 921,
    "maxX" : 1033,
    "minY" : 37,
    "maxY" : 80,
    "prop" : {
      "x" : 921,
      "y" : 43,
      "width" : 106,
      "height" : 37
    },
    "textPosition" : {
      "x" : 936,
      "y" : 59
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1027,
          "y" : 43
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1027,
          "y" : 43
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65640,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65642,
    "reactomeId" : 10057324,
    "displayName" : "ULK3",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1263,
      "y" : 87
    },
    "minX" : 1075,
    "maxX" : 1289,
    "minY" : 70,
    "maxY" : 194,
    "prop" : {
      "x" : 1243,
      "y" : 76,
      "width" : 40,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1244,
      "y" : 76
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1283,
          "y" : 76
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1283,
          "y" : 76
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65640,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1240,
          "y" : 89
        },
        "to" : {
          "x" : 1075,
          "y" : 113
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1234,
          "y" : 94
        },
        "b" : {
          "x" : 1240,
          "y" : 89
        },
        "c" : {
          "x" : 1233,
          "y" : 86
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1233,
          "y" : 86
        }
      }
    }, {
      "edgeId" : 65643,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1265,
          "y" : 101
        },
        "to" : {
          "x" : 1284,
          "y" : 186
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1284,
          "y" : 190
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1284,
          "y" : 190
        }
      }
    } ]
  }, {
    "id" : 65645,
    "reactomeId" : 5632457,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1238,
      "y" : 270
    },
    "minX" : 1217,
    "maxX" : 1291,
    "minY" : 228,
    "maxY" : 285,
    "prop" : {
      "x" : 1217,
      "y" : 255,
      "width" : 42,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1221,
      "y" : 259
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1254,
          "y" : 260
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1254,
          "y" : 260
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65643,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1256,
          "y" : 252
        },
        "to" : {
          "x" : 1291,
          "y" : 228
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1259,
          "y" : 245
        },
        "b" : {
          "x" : 1256,
          "y" : 252
        },
        "c" : {
          "x" : 1264,
          "y" : 251
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1264,
          "y" : 251
        }
      }
    } ]
  }, {
    "id" : 65644,
    "reactomeId" : 5632460,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1220,
      "y" : 156
    },
    "minX" : 1200,
    "maxX" : 1253,
    "minY" : 140,
    "maxY" : 197,
    "prop" : {
      "x" : 1200,
      "y" : 141,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1204,
      "y" : 145
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1235,
          "y" : 146
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1235,
          "y" : 146
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65643,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1232,
          "y" : 174
        },
        "to" : {
          "x" : 1253,
          "y" : 197
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65647,
    "reactomeId" : 10055613,
    "displayName" : "Gpr161",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 491,
      "y" : 923
    },
    "minX" : 454,
    "maxX" : 535,
    "minY" : 904,
    "maxY" : 937,
    "prop" : {
      "x" : 454,
      "y" : 910,
      "width" : 75,
      "height" : 27
    },
    "textPosition" : {
      "x" : 464,
      "y" : 913
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 529,
          "y" : 910
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 529,
          "y" : 910
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65646,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65648,
    "reactomeId" : 10057308,
    "displayName" : "Gpr161",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 497,
      "y" : 1276
    },
    "minX" : 463,
    "maxX" : 538,
    "minY" : 1249,
    "maxY" : 1297,
    "prop" : {
      "x" : 463,
      "y" : 1255,
      "width" : 69,
      "height" : 42
    },
    "textPosition" : {
      "x" : 470,
      "y" : 1265
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 532,
          "y" : 1255
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 532,
          "y" : 1255
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65646,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65651,
    "reactomeId" : 10057347,
    "displayName" : "2p-GLI1,2,3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1594,
      "y" : 1256
    },
    "minX" : 1538,
    "maxX" : 1656,
    "minY" : 1142,
    "maxY" : 1273,
    "prop" : {
      "x" : 1538,
      "y" : 1240,
      "width" : 113,
      "height" : 33
    },
    "textPosition" : {
      "x" : 1555,
      "y" : 1246
    },
    "connectors" : [ {
      "edgeId" : 65649,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1602,
          "y" : 1234
        },
        "to" : {
          "x" : 1656,
          "y" : 1142
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65650,
    "reactomeId" : 9992662,
    "displayName" : "Cdc73",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1572,
      "y" : 1143
    },
    "minX" : 1543,
    "maxX" : 1656,
    "minY" : 1126,
    "maxY" : 1154,
    "prop" : {
      "x" : 1543,
      "y" : 1132,
      "width" : 59,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1549,
      "y" : 1132
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1602,
          "y" : 1132
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1602,
          "y" : 1132
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65649,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1605,
          "y" : 1142
        },
        "to" : {
          "x" : 1656,
          "y" : 1142
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65652,
    "reactomeId" : 10057362,
    "displayName" : "CDC73:2p-GLI",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1784,
      "y" : 1142
    },
    "minX" : 1747,
    "maxX" : 1827,
    "minY" : 1115,
    "maxY" : 1163,
    "prop" : {
      "x" : 1747,
      "y" : 1121,
      "width" : 74,
      "height" : 42
    },
    "textPosition" : {
      "x" : 1747,
      "y" : 1128
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1821,
          "y" : 1121
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1821,
          "y" : 1121
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65649,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65655,
    "reactomeId" : 10057395,
    "displayName" : "2p-GLI2,3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1369,
      "y" : 1500
    },
    "minX" : 1335,
    "maxX" : 1482,
    "minY" : 1489,
    "maxY" : 1703,
    "prop" : {
      "x" : 1335,
      "y" : 1489,
      "width" : 69,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1336,
      "y" : 1489
    },
    "connectors" : [ {
      "edgeId" : 65653,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1375,
          "y" : 1517
        },
        "to" : {
          "x" : 1482,
          "y" : 1703
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65654,
    "reactomeId" : 10057389,
    "displayName" : "SPOP:CUL3:RBX1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1388,
      "y" : 1709
    },
    "minX" : 1332,
    "maxX" : 1883,
    "minY" : 1692,
    "maxY" : 1819,
    "prop" : {
      "x" : 1332,
      "y" : 1698,
      "width" : 112,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1332,
      "y" : 1699
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1444,
          "y" : 1698
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1444,
          "y" : 1698
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65653,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1447,
          "y" : 1705
        },
        "to" : {
          "x" : 1482,
          "y" : 1703
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65661,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1390,
          "y" : 1723
        },
        "to" : {
          "x" : 1412,
          "y" : 1819
        }
      }, {
        "from" : {
          "x" : 1412,
          "y" : 1819
        },
        "to" : {
          "x" : 1883,
          "y" : 1814
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1395,
          "y" : 1729
        },
        "b" : {
          "x" : 1390,
          "y" : 1723
        },
        "c" : {
          "x" : 1388,
          "y" : 1731
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1388,
          "y" : 1731
        }
      }
    } ]
  }, {
    "id" : 65657,
    "reactomeId" : 10057401,
    "displayName" : "Dzip1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1508,
      "y" : 1766
    },
    "minX" : 1472,
    "maxX" : 1551,
    "minY" : 1711,
    "maxY" : 1779,
    "prop" : {
      "x" : 1472,
      "y" : 1754,
      "width" : 73,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1488,
      "y" : 1756
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1545,
          "y" : 1754
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1545,
          "y" : 1754
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65653,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 1507,
          "y" : 1751
        },
        "to" : {
          "x" : 1505,
          "y" : 1711
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1509,
          "y" : 1718
        },
        "b" : {
          "x" : 1505,
          "y" : 1711
        },
        "c" : {
          "x" : 1501,
          "y" : 1718
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 1501,
          "y" : 1718
        }
      }
    } ]
  }, {
    "id" : 65656,
    "reactomeId" : 10057397,
    "displayName" : "2p-GLI:SPOP:CUL3:RBX1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1586,
      "y" : 1703
    },
    "minX" : 1545,
    "maxX" : 1692,
    "minY" : 1673,
    "maxY" : 1728,
    "prop" : {
      "x" : 1545,
      "y" : 1679,
      "width" : 83,
      "height" : 49
    },
    "textPosition" : {
      "x" : 1546,
      "y" : 1679
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1628,
          "y" : 1679
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1628,
          "y" : 1679
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65653,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65658,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1631,
          "y" : 1703
        },
        "to" : {
          "x" : 1670,
          "y" : 1703
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65658,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1631,
          "y" : 1687
        },
        "to" : {
          "x" : 1663,
          "y" : 1674
        }
      }, {
        "from" : {
          "x" : 1663,
          "y" : 1674
        },
        "to" : {
          "x" : 1685,
          "y" : 1692
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1688,
          "y" : 1694
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1688,
          "y" : 1694
        }
      }
    } ]
  }, {
    "id" : 65659,
    "reactomeId" : 9984989,
    "displayName" : "Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1652,
      "y" : 1756
    },
    "minX" : 1621,
    "maxX" : 1883,
    "minY" : 1703,
    "maxY" : 1814,
    "prop" : {
      "x" : 1621,
      "y" : 1745,
      "width" : 62,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1639,
      "y" : 1745
    },
    "connectors" : [ {
      "edgeId" : 65658,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1655,
          "y" : 1739
        },
        "to" : {
          "x" : 1670,
          "y" : 1703
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65661,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1689,
          "y" : 1763
        },
        "to" : {
          "x" : 1883,
          "y" : 1814
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1697,
          "y" : 1761
        },
        "b" : {
          "x" : 1689,
          "y" : 1763
        },
        "c" : {
          "x" : 1695,
          "y" : 1769
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1695,
          "y" : 1769
        }
      }
    } ]
  }, {
    "id" : 65660,
    "reactomeId" : 10057391,
    "displayName" : "ub-2p-GLI2,3:SPOP:CUL3:RBX1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1788,
      "y" : 1702
    },
    "minX" : 1729,
    "maxX" : 1854,
    "minY" : 1671,
    "maxY" : 1727,
    "prop" : {
      "x" : 1729,
      "y" : 1677,
      "width" : 119,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1733,
      "y" : 1692
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1848,
          "y" : 1677
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1848,
          "y" : 1677
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65658,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 65661,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65662,
    "reactomeId" : 9985174,
    "displayName" : "26S proteasome",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1931,
      "y" : 1669
    },
    "minX" : 1875,
    "maxX" : 1994,
    "minY" : 1652,
    "maxY" : 1703,
    "prop" : {
      "x" : 1875,
      "y" : 1658,
      "width" : 113,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1875,
      "y" : 1659
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1988,
          "y" : 1658
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1988,
          "y" : 1658
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 65661,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1916,
          "y" : 1683
        },
        "to" : {
          "x" : 1894,
          "y" : 1697
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1891,
          "y" : 1699
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1891,
          "y" : 1699
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 65667,
    "reactomeId" : 10057427,
    "displayName" : "NUMB:ITCH binds GLI1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2257,
      "y" : 1381
    },
    "minX" : 2230,
    "maxX" : 2293,
    "minY" : 1375,
    "maxY" : 1387,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2230,
        "y" : 1381
      },
      "to" : {
        "x" : 2257,
        "y" : 1381
      }
    }, {
      "from" : {
        "x" : 2257,
        "y" : 1381
      },
      "to" : {
        "x" : 2293,
        "y" : 1383
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2286,
        "y" : 1387
      },
      "b" : {
        "x" : 2293,
        "y" : 1383
      },
      "c" : {
        "x" : 2286,
        "y" : 1379
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2286,
        "y" : 1379
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2257,
        "y" : 1381
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2257,
        "y" : 1381
      }
    },
    "inputs" : [ {
      "id" : 65666,
      "points" : [ {
        "x" : 2223,
        "y" : 1312
      } ]
    }, {
      "id" : 65668,
      "points" : [ {
        "x" : 2198,
        "y" : 1381
      } ]
    } ],
    "outputs" : [ {
      "id" : 65669
    } ]
  }, {
    "id" : 65634,
    "reactomeId" : 10057360,
    "displayName" : "GLI translocates to the nucleus",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1312,
      "y" : 514
    },
    "minX" : 1296,
    "maxX" : 1383,
    "minY" : 345,
    "maxY" : 1240,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1296,
        "y" : 345
      },
      "to" : {
        "x" : 1312,
        "y" : 514
      }
    }, {
      "from" : {
        "x" : 1312,
        "y" : 514
      },
      "to" : {
        "x" : 1383,
        "y" : 1240
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1378,
        "y" : 1233
      },
      "b" : {
        "x" : 1383,
        "y" : 1240
      },
      "c" : {
        "x" : 1386,
        "y" : 1233
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1386,
        "y" : 1233
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1306,
        "y" : 508
      },
      "b" : {
        "x" : 1318,
        "y" : 520
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1312,
        "y" : 514
      }
    },
    "inputs" : [ {
      "id" : 65635
    } ],
    "outputs" : [ {
      "id" : 65636
    } ]
  }, {
    "id" : 65637,
    "reactomeId" : 10057438,
    "displayName" : "SMURF1/2 dissociates from ub-PTCH1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 412,
      "y" : 901
    },
    "minX" : 406,
    "maxX" : 418,
    "minY" : 887,
    "maxY" : 921,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 415,
        "y" : 887
      },
      "to" : {
        "x" : 412,
        "y" : 901
      }
    }, {
      "from" : {
        "x" : 412,
        "y" : 901
      },
      "to" : {
        "x" : 411,
        "y" : 921
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 412,
        "y" : 901
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 412,
        "y" : 901
      }
    },
    "inputs" : [ {
      "id" : 65638
    } ],
    "outputs" : [ {
      "id" : 65639,
      "points" : [ {
        "x" : 202,
        "y" : 1065
      }, {
        "x" : 305,
        "y" : 1127
      }, {
        "x" : 379,
        "y" : 949
      } ]
    }, {
      "id" : 65613,
      "points" : [ {
        "x" : 415,
        "y" : 956
      } ]
    } ]
  }, {
    "id" : 65670,
    "reactomeId" : 10057434,
    "displayName" : "NUMB:ITCH ubiquitinates GLI1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2418,
      "y" : 1388
    },
    "minX" : 2398,
    "maxX" : 2443,
    "minY" : 1382,
    "maxY" : 1394,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2398,
        "y" : 1388
      },
      "to" : {
        "x" : 2418,
        "y" : 1388
      }
    }, {
      "from" : {
        "x" : 2418,
        "y" : 1388
      },
      "to" : {
        "x" : 2443,
        "y" : 1386
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2436,
        "y" : 1391
      },
      "b" : {
        "x" : 2443,
        "y" : 1386
      },
      "c" : {
        "x" : 2436,
        "y" : 1383
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2436,
        "y" : 1383
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2412,
        "y" : 1382
      },
      "b" : {
        "x" : 2424,
        "y" : 1394
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2418,
        "y" : 1388
      }
    },
    "inputs" : [ {
      "id" : 65669,
      "points" : [ {
        "x" : 2382,
        "y" : 1387
      } ]
    }, {
      "id" : 65671,
      "points" : [ {
        "x" : 2372,
        "y" : 1347
      } ]
    } ],
    "outputs" : [ {
      "id" : 65672
    } ],
    "catalysts" : [ {
      "id" : 65669,
      "points" : [ {
        "x" : 2353,
        "y" : 1406
      }, {
        "x" : 2377,
        "y" : 1427
      } ]
    } ]
  }, {
    "id" : 65606,
    "reactomeId" : 10057199,
    "displayName" : "Hh-Npp binds CDON and PTCH",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 336,
      "y" : 520
    },
    "minX" : 330,
    "maxX" : 385,
    "minY" : 514,
    "maxY" : 562,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 334,
        "y" : 562
      },
      "to" : {
        "x" : 336,
        "y" : 520
      }
    }, {
      "from" : {
        "x" : 336,
        "y" : 520
      },
      "to" : {
        "x" : 385,
        "y" : 515
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 379,
        "y" : 520
      },
      "b" : {
        "x" : 385,
        "y" : 515
      },
      "c" : {
        "x" : 378,
        "y" : 512
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 378,
        "y" : 512
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 336,
        "y" : 520
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 336,
        "y" : 520
      }
    },
    "inputs" : [ {
      "id" : 65607,
      "points" : [ {
        "x" : 391,
        "y" : 579
      } ]
    }, {
      "id" : 65608,
      "points" : [ {
        "x" : 67,
        "y" : 604
      } ]
    }, {
      "id" : 65609,
      "points" : [ {
        "x" : 394,
        "y" : 622
      } ]
    } ],
    "outputs" : [ {
      "id" : 65603
    } ]
  }, {
    "id" : 65673,
    "reactomeId" : 10057440,
    "displayName" : "ub-GLI is degraded by the proteasome",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2495,
      "y" : 1269
    },
    "minX" : 2413,
    "maxX" : 2501,
    "minY" : 1255,
    "maxY" : 1359,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 2493,
        "y" : 1359
      },
      "to" : {
        "x" : 2495,
        "y" : 1269
      }
    }, {
      "from" : {
        "x" : 2495,
        "y" : 1269
      },
      "to" : {
        "x" : 2413,
        "y" : 1255
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2489,
        "y" : 1263
      },
      "b" : {
        "x" : 2501,
        "y" : 1275
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2495,
        "y" : 1269
      }
    },
    "inputs" : [ {
      "id" : 65672
    } ],
    "outputs" : [ {
      "id" : 65666,
      "points" : [ {
        "x" : 2264,
        "y" : 1289
      } ]
    }, {
      "id" : 65671,
      "points" : [ {
        "x" : 2375,
        "y" : 1301
      } ]
    } ],
    "catalysts" : [ {
      "id" : 65674,
      "points" : [ {
        "x" : 2492,
        "y" : 1233
      } ]
    } ]
  }, {
    "id" : 65640,
    "reactomeId" : 10057328,
    "displayName" : "ULK3:SUFU dissociates",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1045,
      "y" : 98
    },
    "minX" : 1009,
    "maxX" : 1075,
    "minY" : 83,
    "maxY" : 113,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 1009,
        "y" : 83
      },
      "to" : {
        "x" : 1045,
        "y" : 98
      }
    }, {
      "from" : {
        "x" : 1045,
        "y" : 98
      },
      "to" : {
        "x" : 1075,
        "y" : 113
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 1045,
        "y" : 98
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 1045,
        "y" : 98
      }
    },
    "inputs" : [ {
      "id" : 65641
    } ],
    "outputs" : [ {
      "id" : 65632,
      "points" : [ {
        "x" : 1097,
        "y" : 196
      } ]
    }, {
      "id" : 65642,
      "points" : [ {
        "x" : 1240,
        "y" : 89
      } ]
    } ]
  }, {
    "id" : 65643,
    "reactomeId" : 10057358,
    "displayName" : "ULK3 phosphorylates GLI",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1287,
      "y" : 202
    },
    "minX" : 1253,
    "maxX" : 1293,
    "minY" : 196,
    "maxY" : 228,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1253,
        "y" : 197
      },
      "to" : {
        "x" : 1287,
        "y" : 202
      }
    }, {
      "from" : {
        "x" : 1287,
        "y" : 202
      },
      "to" : {
        "x" : 1291,
        "y" : 228
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1281,
        "y" : 196
      },
      "b" : {
        "x" : 1293,
        "y" : 208
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1287,
        "y" : 202
      }
    },
    "inputs" : [ {
      "id" : 65631,
      "points" : [ {
        "x" : 1218,
        "y" : 198
      } ]
    }, {
      "id" : 65644,
      "points" : [ {
        "x" : 1232,
        "y" : 174
      } ]
    } ],
    "outputs" : [ {
      "id" : 65645,
      "points" : [ {
        "x" : 1256,
        "y" : 252
      } ]
    }, {
      "id" : 65635,
      "points" : [ {
        "x" : 1294,
        "y" : 297
      } ]
    } ],
    "catalysts" : [ {
      "id" : 65642,
      "points" : [ {
        "x" : 1265,
        "y" : 101
      } ]
    } ]
  }, {
    "id" : 65610,
    "reactomeId" : 10057195,
    "displayName" : "Hh-Npp binds GAS1 and PTCH",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 319,
      "y" : 371
    },
    "minX" : 309,
    "maxX" : 368,
    "minY" : 365,
    "maxY" : 392,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 309,
        "y" : 392
      },
      "to" : {
        "x" : 319,
        "y" : 371
      }
    }, {
      "from" : {
        "x" : 319,
        "y" : 371
      },
      "to" : {
        "x" : 368,
        "y" : 367
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 361,
        "y" : 372
      },
      "b" : {
        "x" : 368,
        "y" : 367
      },
      "c" : {
        "x" : 361,
        "y" : 364
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 361,
        "y" : 364
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 319,
        "y" : 371
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 319,
        "y" : 371
      }
    },
    "inputs" : [ {
      "id" : 65611,
      "points" : [ {
        "x" : 382,
        "y" : 429
      } ]
    }, {
      "id" : 65608,
      "points" : [ {
        "x" : 44,
        "y" : 592
      } ]
    }, {
      "id" : 65609,
      "points" : [ {
        "x" : 384,
        "y" : 622
      }, {
        "x" : 284,
        "y" : 563
      } ]
    } ],
    "outputs" : [ {
      "id" : 65604
    } ]
  }, {
    "id" : 65612,
    "reactomeId" : 10057226,
    "displayName" : "PTCH is internalized",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 427,
      "y" : 1109
    },
    "minX" : 418,
    "maxX" : 433,
    "minY" : 996,
    "maxY" : 1298,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 418,
        "y" : 996
      },
      "to" : {
        "x" : 427,
        "y" : 1109
      }
    }, {
      "from" : {
        "x" : 427,
        "y" : 1109
      },
      "to" : {
        "x" : 432,
        "y" : 1298
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 428,
        "y" : 1291
      },
      "b" : {
        "x" : 432,
        "y" : 1298
      },
      "c" : {
        "x" : 436,
        "y" : 1291
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 436,
        "y" : 1291
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 421,
        "y" : 1103
      },
      "b" : {
        "x" : 433,
        "y" : 1115
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 427,
        "y" : 1109
      }
    },
    "inputs" : [ {
      "id" : 65613
    } ],
    "outputs" : [ {
      "id" : 65614
    } ]
  }, {
    "id" : 65615,
    "reactomeId" : 10057253,
    "displayName" : "CSNK1A1 and ADRBK1 dissociate from p-SMO dimer",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 597,
      "y" : 355
    },
    "minX" : 591,
    "maxX" : 603,
    "minY" : 329,
    "maxY" : 380,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 601,
        "y" : 380
      },
      "to" : {
        "x" : 597,
        "y" : 355
      }
    }, {
      "from" : {
        "x" : 597,
        "y" : 355
      },
      "to" : {
        "x" : 599,
        "y" : 329
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 597,
        "y" : 355
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 597,
        "y" : 355
      }
    },
    "inputs" : [ {
      "id" : 65616
    } ],
    "outputs" : [ {
      "id" : 65617,
      "points" : [ {
        "x" : 723,
        "y" : 914
      }, {
        "x" : 848,
        "y" : 484
      } ]
    }, {
      "id" : 65618,
      "points" : [ {
        "x" : 598,
        "y" : 307
      } ]
    }, {
      "id" : 65619,
      "points" : [ {
        "x" : 734,
        "y" : 624
      }, {
        "x" : 803,
        "y" : 491
      } ]
    } ]
  }, {
    "id" : 65646,
    "reactomeId" : 10057310,
    "displayName" : "GPR161 is internalized",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 499,
      "y" : 1075
    },
    "minX" : 491,
    "maxX" : 505,
    "minY" : 940,
    "maxY" : 1252,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 491,
        "y" : 940
      },
      "to" : {
        "x" : 499,
        "y" : 1075
      }
    }, {
      "from" : {
        "x" : 499,
        "y" : 1075
      },
      "to" : {
        "x" : 497,
        "y" : 1252
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 493,
        "y" : 1245
      },
      "b" : {
        "x" : 497,
        "y" : 1252
      },
      "c" : {
        "x" : 501,
        "y" : 1245
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 501,
        "y" : 1245
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 493,
        "y" : 1069
      },
      "b" : {
        "x" : 505,
        "y" : 1081
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 499,
        "y" : 1075
      }
    },
    "inputs" : [ {
      "id" : 65647
    } ],
    "outputs" : [ {
      "id" : 65648
    } ]
  }, {
    "id" : 65649,
    "reactomeId" : 10057364,
    "displayName" : "GLI proteins bind CDC73",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1685,
      "y" : 1143
    },
    "minX" : 1656,
    "maxX" : 1744,
    "minY" : 1137,
    "maxY" : 1149,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1656,
        "y" : 1142
      },
      "to" : {
        "x" : 1685,
        "y" : 1143
      }
    }, {
      "from" : {
        "x" : 1685,
        "y" : 1143
      },
      "to" : {
        "x" : 1744,
        "y" : 1142
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1737,
        "y" : 1146
      },
      "b" : {
        "x" : 1744,
        "y" : 1142
      },
      "c" : {
        "x" : 1737,
        "y" : 1138
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1737,
        "y" : 1138
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1685,
        "y" : 1143
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1685,
        "y" : 1143
      }
    },
    "inputs" : [ {
      "id" : 65650,
      "points" : [ {
        "x" : 1605,
        "y" : 1142
      } ]
    }, {
      "id" : 65651,
      "points" : [ {
        "x" : 1602,
        "y" : 1234
      } ]
    } ],
    "outputs" : [ {
      "id" : 65652
    } ]
  }, {
    "id" : 65653,
    "reactomeId" : 10057403,
    "displayName" : "phosphorylated GLI proteins bind SPOP:CUL3:RBX1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1505,
      "y" : 1702
    },
    "minX" : 1482,
    "maxX" : 1542,
    "minY" : 1696,
    "maxY" : 1708,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1482,
        "y" : 1703
      },
      "to" : {
        "x" : 1505,
        "y" : 1702
      }
    }, {
      "from" : {
        "x" : 1505,
        "y" : 1702
      },
      "to" : {
        "x" : 1542,
        "y" : 1702
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1535,
        "y" : 1706
      },
      "b" : {
        "x" : 1542,
        "y" : 1702
      },
      "c" : {
        "x" : 1535,
        "y" : 1698
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1535,
        "y" : 1698
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1505,
        "y" : 1702
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1505,
        "y" : 1702
      }
    },
    "inputs" : [ {
      "id" : 65654,
      "points" : [ {
        "x" : 1447,
        "y" : 1705
      } ]
    }, {
      "id" : 65655,
      "points" : [ {
        "x" : 1375,
        "y" : 1517
      } ]
    } ],
    "outputs" : [ {
      "id" : 65656
    } ],
    "activators" : [ {
      "id" : 65657,
      "points" : [ {
        "x" : 1507,
        "y" : 1751
      } ]
    } ]
  }, {
    "id" : 65620,
    "reactomeId" : 10017515,
    "displayName" : "HHIP binds Hedgehog",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 291,
      "y" : 109
    },
    "minX" : 285,
    "maxX" : 377,
    "minY" : 95,
    "maxY" : 115,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 291,
        "y" : 95
      },
      "to" : {
        "x" : 291,
        "y" : 109
      }
    }, {
      "from" : {
        "x" : 291,
        "y" : 109
      },
      "to" : {
        "x" : 377,
        "y" : 114
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 370,
        "y" : 118
      },
      "b" : {
        "x" : 377,
        "y" : 114
      },
      "c" : {
        "x" : 370,
        "y" : 110
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 370,
        "y" : 110
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 291,
        "y" : 109
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 291,
        "y" : 109
      }
    },
    "inputs" : [ {
      "id" : 65608,
      "points" : [ {
        "x" : 35,
        "y" : 592
      } ]
    }, {
      "id" : 65621,
      "points" : [ {
        "x" : 396,
        "y" : 41
      } ]
    } ],
    "outputs" : [ {
      "id" : 65622
    } ]
  }, {
    "id" : 65623,
    "reactomeId" : 10055609,
    "displayName" : "GLI proteins bind SUFU",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1080,
      "y" : 1091
    },
    "minX" : 1047,
    "maxX" : 1120,
    "minY" : 1085,
    "maxY" : 1097,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1047,
        "y" : 1089
      },
      "to" : {
        "x" : 1080,
        "y" : 1091
      }
    }, {
      "from" : {
        "x" : 1080,
        "y" : 1091
      },
      "to" : {
        "x" : 1120,
        "y" : 1091
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1113,
        "y" : 1095
      },
      "b" : {
        "x" : 1120,
        "y" : 1091
      },
      "c" : {
        "x" : 1113,
        "y" : 1087
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1113,
        "y" : 1087
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1080,
        "y" : 1091
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1080,
        "y" : 1091
      }
    },
    "inputs" : [ {
      "id" : 65624,
      "points" : [ {
        "x" : 1020,
        "y" : 1076
      } ]
    }, {
      "id" : 65625,
      "points" : [ {
        "x" : 1019,
        "y" : 1100
      } ]
    } ],
    "outputs" : [ {
      "id" : 65626
    } ]
  }, {
    "id" : 65627,
    "reactomeId" : 10057422,
    "displayName" : "GLI:SUFU translocates to the ciliary tip in response to Hh signaling",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1168,
      "y" : 826
    },
    "minX" : 1138,
    "maxX" : 1174,
    "minY" : 336,
    "maxY" : 1075,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1158,
        "y" : 1075
      },
      "to" : {
        "x" : 1168,
        "y" : 826
      }
    }, {
      "from" : {
        "x" : 1168,
        "y" : 826
      },
      "to" : {
        "x" : 1138,
        "y" : 336
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1142,
        "y" : 343
      },
      "b" : {
        "x" : 1138,
        "y" : 336
      },
      "c" : {
        "x" : 1134,
        "y" : 343
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1134,
        "y" : 343
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1162,
        "y" : 820
      },
      "b" : {
        "x" : 1174,
        "y" : 832
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1168,
        "y" : 826
      }
    },
    "inputs" : [ {
      "id" : 65626
    } ],
    "outputs" : [ {
      "id" : 65628
    } ],
    "activators" : [ {
      "id" : 65629,
      "points" : [ {
        "x" : 1063,
        "y" : 833
      } ]
    } ]
  }, {
    "id" : 65658,
    "reactomeId" : 10057407,
    "displayName" : "SPOP:CUL3:RBX1 ubiquitinates GLI2,3",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1697,
      "y" : 1702
    },
    "minX" : 1670,
    "maxX" : 1726,
    "minY" : 1696,
    "maxY" : 1708,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1670,
        "y" : 1703
      },
      "to" : {
        "x" : 1697,
        "y" : 1702
      }
    }, {
      "from" : {
        "x" : 1697,
        "y" : 1702
      },
      "to" : {
        "x" : 1726,
        "y" : 1702
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1719,
        "y" : 1706
      },
      "b" : {
        "x" : 1726,
        "y" : 1702
      },
      "c" : {
        "x" : 1719,
        "y" : 1698
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1719,
        "y" : 1698
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1691,
        "y" : 1696
      },
      "b" : {
        "x" : 1703,
        "y" : 1708
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1697,
        "y" : 1702
      }
    },
    "inputs" : [ {
      "id" : 65656,
      "points" : [ {
        "x" : 1631,
        "y" : 1703
      } ]
    }, {
      "id" : 65659,
      "points" : [ {
        "x" : 1655,
        "y" : 1739
      } ]
    } ],
    "outputs" : [ {
      "id" : 65660
    } ],
    "catalysts" : [ {
      "id" : 65656,
      "points" : [ {
        "x" : 1631,
        "y" : 1687
      }, {
        "x" : 1663,
        "y" : 1674
      } ]
    } ]
  }, {
    "id" : 65661,
    "reactomeId" : 10057393,
    "displayName" : "GLI2,3 are degraded by the proteasome",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1881,
      "y" : 1706
    },
    "minX" : 1851,
    "maxX" : 1887,
    "minY" : 1700,
    "maxY" : 1814,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1851,
        "y" : 1704
      },
      "to" : {
        "x" : 1881,
        "y" : 1706
      }
    }, {
      "from" : {
        "x" : 1881,
        "y" : 1706
      },
      "to" : {
        "x" : 1883,
        "y" : 1814
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1875,
        "y" : 1700
      },
      "b" : {
        "x" : 1887,
        "y" : 1712
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1881,
        "y" : 1706
      }
    },
    "inputs" : [ {
      "id" : 65660
    } ],
    "outputs" : [ {
      "id" : 65654,
      "points" : [ {
        "x" : 1390,
        "y" : 1723
      }, {
        "x" : 1412,
        "y" : 1819
      } ]
    }, {
      "id" : 65659,
      "points" : [ {
        "x" : 1689,
        "y" : 1763
      } ]
    } ],
    "catalysts" : [ {
      "id" : 65662,
      "points" : [ {
        "x" : 1916,
        "y" : 1683
      } ]
    } ]
  }, {
    "id" : 65663,
    "reactomeId" : 10055717,
    "displayName" : "NUMB binds ITCH",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2214,
      "y" : 1253
    },
    "minX" : 2208,
    "maxX" : 2220,
    "minY" : 1225,
    "maxY" : 1284,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2214,
        "y" : 1225
      },
      "to" : {
        "x" : 2214,
        "y" : 1253
      }
    }, {
      "from" : {
        "x" : 2214,
        "y" : 1253
      },
      "to" : {
        "x" : 2220,
        "y" : 1284
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2215,
        "y" : 1278
      },
      "b" : {
        "x" : 2220,
        "y" : 1284
      },
      "c" : {
        "x" : 2223,
        "y" : 1276
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2223,
        "y" : 1276
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2214,
        "y" : 1253
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2214,
        "y" : 1253
      }
    },
    "inputs" : [ {
      "id" : 65664,
      "points" : [ {
        "x" : 2230,
        "y" : 1207
      } ]
    }, {
      "id" : 65665,
      "points" : [ {
        "x" : 2182,
        "y" : 1209
      } ]
    } ],
    "outputs" : [ {
      "id" : 65666
    } ]
  }, {
    "id" : 65598,
    "reactomeId" : 10057215,
    "displayName" : "SMO translocates to the cilium",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 750,
      "y" : 1066
    },
    "minX" : 631,
    "maxX" : 926,
    "minY" : 969,
    "maxY" : 1254,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 926,
        "y" : 1254
      },
      "to" : {
        "x" : 750,
        "y" : 1066
      }
    }, {
      "from" : {
        "x" : 750,
        "y" : 1066
      },
      "to" : {
        "x" : 631,
        "y" : 969
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 639,
        "y" : 970
      },
      "b" : {
        "x" : 631,
        "y" : 969
      },
      "c" : {
        "x" : 634,
        "y" : 976
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 634,
        "y" : 976
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 744,
        "y" : 1060
      },
      "b" : {
        "x" : 756,
        "y" : 1072
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 750,
        "y" : 1066
      }
    },
    "inputs" : [ {
      "id" : 65599
    } ],
    "outputs" : [ {
      "id" : 65600
    } ],
    "activators" : [ {
      "id" : 65601,
      "points" : [ {
        "x" : 640,
        "y" : 1253
      } ]
    }, {
      "id" : 65602,
      "points" : [ {
        "x" : 443,
        "y" : 243
      }, {
        "x" : 518,
        "y" : 377
      }, {
        "x" : 565,
        "y" : 1066
      } ]
    }, {
      "id" : 65603,
      "points" : [ {
        "x" : 447,
        "y" : 533
      }, {
        "x" : 511,
        "y" : 599
      }, {
        "x" : 550,
        "y" : 1100
      } ]
    }, {
      "id" : 65604,
      "points" : [ {
        "x" : 430,
        "y" : 391
      }, {
        "x" : 512,
        "y" : 499
      }, {
        "x" : 558,
        "y" : 1085
      } ]
    }, {
      "id" : 65605,
      "points" : [ {
        "x" : 812,
        "y" : 1062
      } ]
    } ]
  }, {
    "id" : 65630,
    "reactomeId" : 10057419,
    "displayName" : "GLI:SUFU dissociates",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1139,
      "y" : 283
    },
    "minX" : 1133,
    "maxX" : 1145,
    "minY" : 257,
    "maxY" : 308,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 1138,
        "y" : 308
      },
      "to" : {
        "x" : 1139,
        "y" : 283
      }
    }, {
      "from" : {
        "x" : 1139,
        "y" : 283
      },
      "to" : {
        "x" : 1139,
        "y" : 257
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 1139,
        "y" : 283
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 1139,
        "y" : 283
      }
    },
    "inputs" : [ {
      "id" : 65628
    } ],
    "outputs" : [ {
      "id" : 65631,
      "points" : [ {
        "x" : 1167,
        "y" : 218
      } ]
    }, {
      "id" : 65632,
      "points" : [ {
        "x" : 1109,
        "y" : 224
      } ]
    } ],
    "activators" : [ {
      "id" : 65633,
      "points" : [ {
        "x" : 692,
        "y" : 219
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 65686,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1665,
      "y" : 1476
    },
    "minX" : 1296,
    "maxX" : 2035,
    "minY" : 1069,
    "maxY" : 1883,
    "prop" : {
      "x" : 1296,
      "y" : 1069,
      "width" : 739,
      "height" : 814
    },
    "textPosition" : {
      "x" : 1428,
      "y" : 1116
    },
    "insets" : {
      "x" : 1306,
      "y" : 1079,
      "width" : 719,
      "height" : 794
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 65636, 65651, 65689, 65691, 65650, 65649, 65652, 65692, 65653, 65654, 65655, 65656, 65660, 65658, 65659, 65662, 65661, 65657 ]
  }, {
    "id" : 65675,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1350,
      "y" : 1495
    },
    "minX" : 86,
    "maxX" : 2614,
    "minY" : 975,
    "maxY" : 2016,
    "prop" : {
      "x" : 86,
      "y" : 975,
      "width" : 2528,
      "height" : 1041
    },
    "textPosition" : {
      "x" : 1042,
      "y" : 1311
    },
    "insets" : {
      "x" : 96,
      "y" : 985,
      "width" : 2508,
      "height" : 1021
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 65639, 65676, 65623, 65624, 65625, 65626, 65686, 65605, 65612, 65598, 65646, 65663, 65666, 65665, 65664, 65668, 65669, 65667, 65670, 65672, 65671, 65673, 65674 ]
  }, {
    "id" : 65690,
    "reactomeId" : 18730,
    "displayName" : "cilium",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 907,
      "y" : 495
    },
    "minX" : 401,
    "maxX" : 1413,
    "minY" : 0,
    "maxY" : 991,
    "prop" : {
      "x" : 401,
      "y" : 0,
      "width" : 1012,
      "height" : 991
    },
    "textPosition" : {
      "x" : 880,
      "y" : 479
    },
    "insets" : {
      "x" : 411,
      "y" : 10,
      "width" : 992,
      "height" : 971
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 65637, 65633 ]
  }, {
    "id" : 65676,
    "reactomeId" : 528865,
    "displayName" : "endocytic vesicle lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 707,
      "y" : 1360
    },
    "minX" : 412,
    "maxX" : 1002,
    "minY" : 1268,
    "maxY" : 1453,
    "prop" : {
      "x" : 412,
      "y" : 1268,
      "width" : 590,
      "height" : 185
    },
    "textPosition" : {
      "x" : 764,
      "y" : 1374
    },
    "insets" : {
      "x" : 422,
      "y" : 1278,
      "width" : 570,
      "height" : 165
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 65614, 65599, 65601, 65648 ]
  } ],
  "notes" : [ ],
  "links" : [ {
    "id" : 65691,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1543,
      "y" : 1391
    },
    "minX" : 1499,
    "maxX" : 1587,
    "minY" : 1279,
    "maxY" : 1503,
    "segments" : [ {
      "from" : {
        "x" : 1499,
        "y" : 1503
      },
      "to" : {
        "x" : 1587,
        "y" : 1279
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1537,
        "y" : 1385
      },
      "b" : {
        "x" : 1549,
        "y" : 1397
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1543,
        "y" : 1391
      }
    },
    "inputs" : [ {
      "id" : 65689
    } ],
    "outputs" : [ {
      "id" : 65651
    } ]
  }, {
    "id" : 65692,
    "renderableClass" : "EntitySetAndEntitySetLink",
    "position" : {
      "x" : 1478,
      "y" : 1381
    },
    "minX" : 1379,
    "maxX" : 1578,
    "minY" : 1279,
    "maxY" : 1483,
    "segments" : [ {
      "from" : {
        "x" : 1379,
        "y" : 1483
      },
      "to" : {
        "x" : 1578,
        "y" : 1279
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1472,
        "y" : 1375
      },
      "b" : {
        "x" : 1484,
        "y" : 1387
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1478,
        "y" : 1381
      }
    },
    "inputs" : [ {
      "id" : 65655
    } ],
    "outputs" : [ {
      "id" : 65651
    } ]
  } ],
  "shadows" : [ {
    "id" : 65693,
    "reactomeId" : 10100335,
    "displayName" : "Ligand-receptor interactions",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 236,
      "y" : 336
    },
    "minX" : -10,
    "maxX" : 482,
    "minY" : 11,
    "maxY" : 662,
    "prop" : {
      "x" : -10,
      "y" : 176,
      "width" : 371,
      "height" : 486
    },
    "points" : [ {
      "x" : -10,
      "y" : 11
    }, {
      "x" : 482,
      "y" : 11
    }, {
      "x" : 482,
      "y" : 662
    }, {
      "x" : -10,
      "y" : 662
    } ],
    "colour" : "#4684ee"
  }, {
    "id" : 65694,
    "reactomeId" : 10101217,
    "displayName" : "Activation of SMO",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 681,
      "y" : 739
    },
    "minX" : 361,
    "maxX" : 1002,
    "minY" : 176,
    "maxY" : 1302,
    "prop" : {
      "x" : 361,
      "y" : 662,
      "width" : 641,
      "height" : 640
    },
    "points" : [ {
      "x" : 361,
      "y" : 176
    }, {
      "x" : 1002,
      "y" : 176
    }, {
      "x" : 1002,
      "y" : 1302
    }, {
      "x" : 361,
      "y" : 1302
    } ],
    "colour" : "#dc3912"
  } ],
  "minX" : 0,
  "maxX" : 2614,
  "minY" : 0,
  "maxY" : 2016,
  "disease" : false
}