{
  "dbId" : 10100225,
  "stId" : "R-MMU-5627117",
  "speciesName" : "Mus musculus",
  "nodes" : [ {
    "dbId" : 5625908,
    "stId" : "R-MMU-5625908",
    "displayName" : "Rhoc [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q62159",
    "standardIdentifier" : "uniprot:Q62159",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Rhoc", "Arhc" ],
    "parents" : [ 5666176 ],
    "children" : [ ]
  }, {
    "dbId" : 9686545,
    "stId" : "R-ALL-9686545",
    "displayName" : "netarsudil [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "9322",
    "standardIdentifier" : "iuphar.ligand:9322",
    "parents" : [ 9686558 ],
    "children" : [ ]
  }, {
    "dbId" : 5625906,
    "stId" : "R-MMU-5625906",
    "displayName" : "Rhob [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P62746",
    "standardIdentifier" : "uniprot:P62746",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Rhob", "Arhb" ],
    "parents" : [ 5666176 ],
    "children" : [ ]
  }, {
    "dbId" : 10014609,
    "stId" : "R-MMU-419058",
    "displayName" : "ROCK2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P70336",
    "standardIdentifier" : "uniprot:P70336",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10014611 ],
    "children" : [ ]
  }, {
    "dbId" : 5666175,
    "stId" : "R-MMU-5666175",
    "displayName" : "RhoA,B,C:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 61067 ],
    "parents" : [ 10014613 ],
    "children" : [ 29438, 5666176 ]
  }, {
    "dbId" : 10014611,
    "stId" : "R-MMU-419057",
    "displayName" : "ROCK1,ROCK2 [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "diagramIds" : [ 61068 ],
    "parents" : [ 10014613, 10014615 ],
    "children" : [ 10003811, 10014609 ]
  }, {
    "dbId" : 9680440,
    "stId" : "R-ALL-9680440",
    "displayName" : "ripasudil [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "10423",
    "standardIdentifier" : "iuphar.ligand:10423",
    "chebiIdentifier" : "chebi:136046",
    "parents" : [ 9686558 ],
    "children" : [ ]
  }, {
    "dbId" : 10100343,
    "stId" : "R-MMU-5627123",
    "displayName" : "RHO GTPases activate PAKs",
    "schemaClass" : "Pathway",
    "speciesId" : 48892,
    "diagramIds" : [ 61080 ]
  }, {
    "dbId" : 9686558,
    "stId" : "R-ALL-9686558",
    "displayName" : "ROCKi [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 0,
    "diagramIds" : [ 61072 ],
    "parents" : [ 10014615 ],
    "children" : [ 9680440, 9686545 ]
  }, {
    "dbId" : 10014613,
    "stId" : "R-MMU-422483",
    "displayName" : "Activated ROCK:RhoA/B/C:GTP [plasma membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 61069 ],
    "parents" : [ ],
    "children" : [ 10014611, 5666175 ]
  }, {
    "dbId" : 10014615,
    "stId" : "R-MMU-9680444",
    "displayName" : "ROCK1,ROCK2:ROCKi [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48892,
    "diagramIds" : [ 61070 ],
    "parents" : [ ],
    "children" : [ 9686558, 10014611 ]
  }, {
    "dbId" : 5666176,
    "stId" : "R-MMU-5666176",
    "displayName" : "Rhoa,b,c [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 48892,
    "parents" : [ 5666175 ],
    "children" : [ 5625902, 5625906, 5625908 ]
  }, {
    "dbId" : 10003811,
    "stId" : "R-MMU-212509",
    "displayName" : "ROCK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "P70335",
    "standardIdentifier" : "uniprot:P70335",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10014611 ],
    "children" : [ ]
  }, {
    "dbId" : 5625902,
    "stId" : "R-MMU-5625902",
    "displayName" : "Rhoa [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48892,
    "identifier" : "Q9QUI0",
    "standardIdentifier" : "uniprot:Q9QUI0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Rhoa", "Arha", "Arha2" ],
    "parents" : [ 5666176 ],
    "children" : [ ]
  }, {
    "dbId" : 29438,
    "stId" : "R-ALL-29438",
    "displayName" : "GTP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "37565",
    "standardIdentifier" : "chebi:37565",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 5666175 ],
    "children" : [ ]
  }, {
    "dbId" : 10100005,
    "stId" : "R-MMU-373755",
    "displayName" : "Semaphorin interactions",
    "schemaClass" : "Pathway",
    "speciesId" : 48892,
    "diagramIds" : [ 61079 ]
  } ],
  "edges" : [ {
    "dbId" : 10089833,
    "stId" : "R-MMU-9680443",
    "displayName" : "ROCK1,2 bind ROCKi",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 9686558, 10014611 ],
    "outputs" : [ 10014615 ],
    "efs" : [ ],
    "diagramIds" : [ 61071 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10014617,
    "stId" : "R-MMU-419049",
    "displayName" : "ROCK activation by RHO",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10014611, 5666175 ],
    "outputs" : [ 10014613 ],
    "efs" : [ ],
    "inhibitors" : [ 10014615 ],
    "diagramIds" : [ 61066 ],
    "entityFunctionalStatus" : [ ]
  } ]
}