{
  "dbId" : 10099761,
  "stableId" : "R-MMU-202403",
  "displayName" : "TCR signaling",
  "nodes" : [ {
    "id" : 28928,
    "reactomeId" : 10004420,
    "displayName" : "phosphorylated PLC-gamma1 bound to SLP-76",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1637,
      "y" : 1787
    },
    "minX" : 1572,
    "maxX" : 1709,
    "minY" : 1756,
    "maxY" : 1812,
    "prop" : {
      "x" : 1572,
      "y" : 1762,
      "width" : 131,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1582,
      "y" : 1763
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1703,
          "y" : 1762
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1703,
          "y" : 1762
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28927,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28930,
    "reactomeId" : 179856,
    "displayName" : "PI(4,5)P2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2168,
      "y" : 1794
    },
    "minX" : 2133,
    "maxX" : 2216,
    "minY" : 1725,
    "maxY" : 1832,
    "prop" : {
      "x" : 2133,
      "y" : 1779,
      "width" : 70,
      "height" : 30
    },
    "textPosition" : {
      "x" : 2135,
      "y" : 1783
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2198,
          "y" : 1784
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2198,
          "y" : 1784
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28929,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2175,
          "y" : 1812
        },
        "to" : {
          "x" : 2188,
          "y" : 1832
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28932,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2178,
          "y" : 1776
        },
        "to" : {
          "x" : 2216,
          "y" : 1725
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28931,
    "reactomeId" : 10004458,
    "displayName" : "Activated PLC gamma1 bound to PIP2",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2332,
      "y" : 1800
    },
    "minX" : 2272,
    "maxX" : 2398,
    "minY" : 1769,
    "maxY" : 1825,
    "prop" : {
      "x" : 2272,
      "y" : 1775,
      "width" : 120,
      "height" : 50
    },
    "textPosition" : {
      "x" : 2277,
      "y" : 1776
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2392,
          "y" : 1775
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2392,
          "y" : 1775
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28929,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28933,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2185,
      "y" : 1705
    },
    "minX" : 2164,
    "maxX" : 2216,
    "minY" : 1689,
    "maxY" : 1725,
    "prop" : {
      "x" : 2164,
      "y" : 1690,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 2168,
      "y" : 1694
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2202,
          "y" : 1695
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2202,
          "y" : 1695
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28932,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2210,
          "y" : 1718
        },
        "to" : {
          "x" : 2216,
          "y" : 1725
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 28934,
    "reactomeId" : 112275,
    "displayName" : "DAGs",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2520,
      "y" : 1792
    },
    "minX" : 2430,
    "maxX" : 2546,
    "minY" : 1726,
    "maxY" : 1807,
    "prop" : {
      "x" : 2496,
      "y" : 1777,
      "width" : 49,
      "height" : 30
    },
    "textPosition" : {
      "x" : 2500,
      "y" : 1781
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2540,
          "y" : 1782
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2540,
          "y" : 1782
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28932,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2499,
          "y" : 1774
        },
        "to" : {
          "x" : 2430,
          "y" : 1726
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2491,
          "y" : 1773
        },
        "b" : {
          "x" : 2499,
          "y" : 1774
        },
        "c" : {
          "x" : 2496,
          "y" : 1767
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2496,
          "y" : 1767
        }
      }
    } ]
  }, {
    "id" : 28935,
    "reactomeId" : 114520,
    "displayName" : "I(1,4,5)P3",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2500,
      "y" : 1666
    },
    "minX" : 2430,
    "maxX" : 2539,
    "minY" : 1650,
    "maxY" : 1726,
    "prop" : {
      "x" : 2463,
      "y" : 1651,
      "width" : 75,
      "height" : 30
    },
    "textPosition" : {
      "x" : 2466,
      "y" : 1655
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2533,
          "y" : 1656
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2533,
          "y" : 1656
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28932,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2482,
          "y" : 1684
        },
        "to" : {
          "x" : 2430,
          "y" : 1726
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2479,
          "y" : 1691
        },
        "b" : {
          "x" : 2482,
          "y" : 1684
        },
        "c" : {
          "x" : 2474,
          "y" : 1685
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2474,
          "y" : 1685
        }
      }
    } ]
  }, {
    "id" : 28936,
    "reactomeId" : 10004479,
    "displayName" : "p-PLCG",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 2450,
      "y" : 1798
    },
    "minX" : 2384,
    "maxX" : 2477,
    "minY" : 1730,
    "maxY" : 1809,
    "prop" : {
      "x" : 2424,
      "y" : 1787,
      "width" : 53,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2425,
      "y" : 1787
    },
    "connectors" : [ {
      "edgeId" : 28932,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2439,
          "y" : 1781
        },
        "to" : {
          "x" : 2391,
          "y" : 1737
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2388,
          "y" : 1734
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2388,
          "y" : 1734
        }
      }
    } ]
  }, {
    "id" : 28938,
    "reactomeId" : 10004315,
    "displayName" : "phospho-Trat1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3237,
      "y" : 1748
    },
    "minX" : 3173,
    "maxX" : 3307,
    "minY" : 1697,
    "maxY" : 1774,
    "prop" : {
      "x" : 3173,
      "y" : 1723,
      "width" : 128,
      "height" : 51
    },
    "textPosition" : {
      "x" : 3187,
      "y" : 1738
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3301,
          "y" : 1723
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3301,
          "y" : 1723
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28937,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3237,
          "y" : 1720
        },
        "to" : {
          "x" : 3237,
          "y" : 1697
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28939,
    "reactomeId" : 9989243,
    "displayName" : "PI3K",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3132,
      "y" : 1714
    },
    "minX" : 3115,
    "maxX" : 3237,
    "minY" : 1697,
    "maxY" : 1725,
    "prop" : {
      "x" : 3115,
      "y" : 1703,
      "width" : 35,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3115,
      "y" : 1704
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3150,
          "y" : 1703
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3150,
          "y" : 1703
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28937,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3153,
          "y" : 1711
        },
        "to" : {
          "x" : 3237,
          "y" : 1697
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28940,
    "reactomeId" : 10004317,
    "displayName" : "PI3K bound to TRAT",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3236,
      "y" : 1632
    },
    "minX" : 3171,
    "maxX" : 3307,
    "minY" : 1511,
    "maxY" : 1643,
    "prop" : {
      "x" : 3171,
      "y" : 1621,
      "width" : 130,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3171,
      "y" : 1622
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3301,
          "y" : 1621
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3301,
          "y" : 1621
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28937,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28941,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3247,
          "y" : 1618
        },
        "to" : {
          "x" : 3278,
          "y" : 1593
        }
      }, {
        "from" : {
          "x" : 3278,
          "y" : 1593
        },
        "to" : {
          "x" : 3277,
          "y" : 1513
        }
      }, {
        "from" : {
          "x" : 3277,
          "y" : 1513
        },
        "to" : {
          "x" : 3218,
          "y" : 1515
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3214,
          "y" : 1515
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3214,
          "y" : 1515
        }
      }
    } ]
  }, {
    "id" : 28942,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3164,
      "y" : 1569
    },
    "minX" : 3144,
    "maxX" : 3201,
    "minY" : 1542,
    "maxY" : 1584,
    "prop" : {
      "x" : 3144,
      "y" : 1554,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3148,
      "y" : 1558
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3179,
          "y" : 1559
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3179,
          "y" : 1559
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28941,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3187,
          "y" : 1554
        },
        "to" : {
          "x" : 3201,
          "y" : 1542
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28943,
    "reactomeId" : 179856,
    "displayName" : "PI(4,5)P2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3234,
      "y" : 1571
    },
    "minX" : 3199,
    "maxX" : 3270,
    "minY" : 1542,
    "maxY" : 1586,
    "prop" : {
      "x" : 3199,
      "y" : 1556,
      "width" : 70,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3201,
      "y" : 1560
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3264,
          "y" : 1561
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3264,
          "y" : 1561
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28941,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3216,
          "y" : 1553
        },
        "to" : {
          "x" : 3201,
          "y" : 1542
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28944,
    "reactomeId" : 179838,
    "displayName" : "PI(3,4,5)P3",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3239,
      "y" : 1443
    },
    "minX" : 3146,
    "maxX" : 3281,
    "minY" : 1396,
    "maxY" : 1492,
    "prop" : {
      "x" : 3198,
      "y" : 1428,
      "width" : 82,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3200,
      "y" : 1432
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3275,
          "y" : 1433
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3275,
          "y" : 1433
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28941,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3227,
          "y" : 1461
        },
        "to" : {
          "x" : 3202,
          "y" : 1492
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3226,
          "y" : 1469
        },
        "b" : {
          "x" : 3227,
          "y" : 1461
        },
        "c" : {
          "x" : 3220,
          "y" : 1464
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3220,
          "y" : 1464
        }
      }
    }, {
      "edgeId" : 28946,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3238,
          "y" : 1425
        },
        "to" : {
          "x" : 3238,
          "y" : 1396
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 29046,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3195,
          "y" : 1436
        },
        "to" : {
          "x" : 3146,
          "y" : 1428
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28945,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3164,
      "y" : 1475
    },
    "minX" : 3144,
    "maxX" : 3202,
    "minY" : 1459,
    "maxY" : 1492,
    "prop" : {
      "x" : 3144,
      "y" : 1460,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3148,
      "y" : 1464
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3180,
          "y" : 1465
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3180,
          "y" : 1465
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28941,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3188,
          "y" : 1484
        },
        "to" : {
          "x" : 3202,
          "y" : 1492
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3196,
          "y" : 1484
        },
        "b" : {
          "x" : 3188,
          "y" : 1484
        },
        "c" : {
          "x" : 3192,
          "y" : 1491
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3192,
          "y" : 1491
        }
      }
    } ]
  }, {
    "id" : 28947,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3189,
      "y" : 1412
    },
    "minX" : 3146,
    "maxX" : 3238,
    "minY" : 1396,
    "maxY" : 1428,
    "prop" : {
      "x" : 3171,
      "y" : 1398,
      "width" : 37,
      "height" : 28
    },
    "textPosition" : {
      "x" : 3172,
      "y" : 1401
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3203,
          "y" : 1403
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3203,
          "y" : 1403
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28946,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3211,
          "y" : 1405
        },
        "to" : {
          "x" : 3238,
          "y" : 1396
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 29046,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3168,
          "y" : 1418
        },
        "to" : {
          "x" : 3146,
          "y" : 1428
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 28948,
    "reactomeId" : 202247,
    "displayName" : "PI(3,4)P2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3238,
      "y" : 1256
    },
    "minX" : 3203,
    "maxX" : 3274,
    "minY" : 1240,
    "maxY" : 1321,
    "prop" : {
      "x" : 3203,
      "y" : 1241,
      "width" : 70,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3205,
      "y" : 1245
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3268,
          "y" : 1246
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3268,
          "y" : 1246
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28946,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3238,
          "y" : 1274
        },
        "to" : {
          "x" : 3238,
          "y" : 1321
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3242,
          "y" : 1281
        },
        "b" : {
          "x" : 3238,
          "y" : 1274
        },
        "c" : {
          "x" : 3234,
          "y" : 1281
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3234,
          "y" : 1281
        }
      }
    } ]
  }, {
    "id" : 28949,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3175,
      "y" : 1265
    },
    "minX" : 3132,
    "maxX" : 3238,
    "minY" : 1231,
    "maxY" : 1321,
    "prop" : {
      "x" : 3162,
      "y" : 1250,
      "width" : 27,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3166,
      "y" : 1254
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3184,
          "y" : 1255
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3184,
          "y" : 1255
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28946,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3192,
          "y" : 1277
        },
        "to" : {
          "x" : 3238,
          "y" : 1321
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3200,
          "y" : 1279
        },
        "b" : {
          "x" : 3192,
          "y" : 1277
        },
        "c" : {
          "x" : 3194,
          "y" : 1285
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3194,
          "y" : 1285
        }
      }
    }, {
      "edgeId" : 29046,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3159,
          "y" : 1254
        },
        "to" : {
          "x" : 3132,
          "y" : 1231
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3151,
          "y" : 1253
        },
        "b" : {
          "x" : 3159,
          "y" : 1254
        },
        "c" : {
          "x" : 3156,
          "y" : 1246
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3156,
          "y" : 1246
        }
      }
    } ]
  }, {
    "id" : 28950,
    "reactomeId" : 10004400,
    "displayName" : "Inpp5d",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3169,
      "y" : 1358
    },
    "minX" : 3142,
    "maxX" : 3230,
    "minY" : 1341,
    "maxY" : 1369,
    "prop" : {
      "x" : 3142,
      "y" : 1347,
      "width" : 54,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3143,
      "y" : 1347
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3196,
          "y" : 1347
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3196,
          "y" : 1347
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28946,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3199,
          "y" : 1357
        },
        "to" : {
          "x" : 3222,
          "y" : 1357
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3226,
          "y" : 1357
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3226,
          "y" : 1357
        }
      }
    } ]
  }, {
    "id" : 28952,
    "reactomeId" : 202277,
    "displayName" : "PIP3, PI(3,4)P2",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 3238,
      "y" : 1119
    },
    "minX" : 3188,
    "maxX" : 3289,
    "minY" : 1086,
    "maxY" : 1130,
    "prop" : {
      "x" : 3188,
      "y" : 1108,
      "width" : 101,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3188,
      "y" : 1108
    },
    "connectors" : [ {
      "edgeId" : 28951,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3227,
          "y" : 1102
        },
        "to" : {
          "x" : 3206,
          "y" : 1086
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28953,
    "reactomeId" : 10004205,
    "displayName" : "PDPK1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3134,
      "y" : 1119
    },
    "minX" : 3110,
    "maxX" : 3206,
    "minY" : 1086,
    "maxY" : 1130,
    "prop" : {
      "x" : 3110,
      "y" : 1108,
      "width" : 48,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3110,
      "y" : 1108
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3158,
          "y" : 1108
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3158,
          "y" : 1108
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28951,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3158,
          "y" : 1105
        },
        "to" : {
          "x" : 3206,
          "y" : 1086
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28954,
    "reactomeId" : 10004207,
    "displayName" : "PDK1:PIP2,PIP3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3239,
      "y" : 934
    },
    "minX" : 3023,
    "maxX" : 3317,
    "minY" : 528,
    "maxY" : 945,
    "prop" : {
      "x" : 3188,
      "y" : 923,
      "width" : 103,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3188,
      "y" : 924
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3291,
          "y" : 923
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3291,
          "y" : 923
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28951,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28964,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3255,
          "y" : 920
        },
        "to" : {
          "x" : 3317,
          "y" : 883
        }
      }, {
        "from" : {
          "x" : 3317,
          "y" : 883
        },
        "to" : {
          "x" : 3314,
          "y" : 529
        }
      }, {
        "from" : {
          "x" : 3314,
          "y" : 529
        },
        "to" : {
          "x" : 3228,
          "y" : 532
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3224,
          "y" : 532
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3224,
          "y" : 532
        }
      }
    }, {
      "edgeId" : 28968,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3185,
          "y" : 927
        },
        "to" : {
          "x" : 3023,
          "y" : 905
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28956,
    "reactomeId" : 10003791,
    "displayName" : "PRKCQ",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3123,
      "y" : 875
    },
    "minX" : 3076,
    "maxX" : 3218,
    "minY" : 846,
    "maxY" : 893,
    "prop" : {
      "x" : 3076,
      "y" : 857,
      "width" : 94,
      "height" : 36
    },
    "textPosition" : {
      "x" : 3099,
      "y" : 864
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3170,
          "y" : 857
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3170,
          "y" : 857
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28955,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3173,
          "y" : 860
        },
        "to" : {
          "x" : 3218,
          "y" : 846
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28957,
    "reactomeId" : 112275,
    "displayName" : "DAGs",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3240,
      "y" : 882
    },
    "minX" : 3216,
    "maxX" : 3266,
    "minY" : 846,
    "maxY" : 897,
    "prop" : {
      "x" : 3216,
      "y" : 867,
      "width" : 49,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3220,
      "y" : 871
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3260,
          "y" : 872
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3260,
          "y" : 872
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28955,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3230,
          "y" : 864
        },
        "to" : {
          "x" : 3218,
          "y" : 846
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28958,
    "reactomeId" : 10004444,
    "displayName" : "PKC-theta (open): DAG",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3228,
      "y" : 766
    },
    "minX" : 3121,
    "maxX" : 3293,
    "minY" : 738,
    "maxY" : 784,
    "prop" : {
      "x" : 3170,
      "y" : 748,
      "width" : 117,
      "height" : 36
    },
    "textPosition" : {
      "x" : 3186,
      "y" : 749
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3287,
          "y" : 748
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3287,
          "y" : 748
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28955,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28959,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3167,
          "y" : 750
        },
        "to" : {
          "x" : 3121,
          "y" : 738
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28960,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3095,
      "y" : 770
    },
    "minX" : 3075,
    "maxX" : 3121,
    "minY" : 738,
    "maxY" : 785,
    "prop" : {
      "x" : 3075,
      "y" : 755,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3079,
      "y" : 759
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3110,
          "y" : 760
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3110,
          "y" : 760
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28959,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3107,
          "y" : 752
        },
        "to" : {
          "x" : 3121,
          "y" : 738
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28961,
    "reactomeId" : 10004379,
    "displayName" : "p-Y90-PKC-theta:DAG",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3236,
      "y" : 605
    },
    "minX" : 3121,
    "maxX" : 3301,
    "minY" : 556,
    "maxY" : 649,
    "prop" : {
      "x" : 3178,
      "y" : 587,
      "width" : 117,
      "height" : 36
    },
    "textPosition" : {
      "x" : 3180,
      "y" : 588
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3295,
          "y" : 587
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3295,
          "y" : 587
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28959,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3188,
          "y" : 626
        },
        "to" : {
          "x" : 3121,
          "y" : 649
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3183,
          "y" : 632
        },
        "b" : {
          "x" : 3188,
          "y" : 626
        },
        "c" : {
          "x" : 3180,
          "y" : 624
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3180,
          "y" : 624
        }
      }
    }, {
      "edgeId" : 28964,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3227,
          "y" : 584
        },
        "to" : {
          "x" : 3212,
          "y" : 556
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28962,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3084,
      "y" : 614
    },
    "minX" : 3064,
    "maxX" : 3121,
    "minY" : 598,
    "maxY" : 649,
    "prop" : {
      "x" : 3064,
      "y" : 599,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3068,
      "y" : 603
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3100,
          "y" : 604
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3100,
          "y" : 604
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28959,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3099,
          "y" : 632
        },
        "to" : {
          "x" : 3121,
          "y" : 649
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3107,
          "y" : 633
        },
        "b" : {
          "x" : 3099,
          "y" : 632
        },
        "c" : {
          "x" : 3102,
          "y" : 639
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3102,
          "y" : 639
        }
      }
    } ]
  }, {
    "id" : 28963,
    "reactomeId" : 10004253,
    "displayName" : "Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3238,
      "y" : 685
    },
    "minX" : 3129,
    "maxX" : 3303,
    "minY" : 640,
    "maxY" : 724,
    "prop" : {
      "x" : 3179,
      "y" : 646,
      "width" : 118,
      "height" : 78
    },
    "textPosition" : {
      "x" : 3178,
      "y" : 647
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3297,
          "y" : 646
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3297,
          "y" : 646
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28959,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3176,
          "y" : 686
        },
        "to" : {
          "x" : 3137,
          "y" : 687
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3133,
          "y" : 687
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3133,
          "y" : 687
        }
      }
    } ]
  }, {
    "id" : 28965,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3139,
      "y" : 582
    },
    "minX" : 3119,
    "maxX" : 3212,
    "minY" : 556,
    "maxY" : 597,
    "prop" : {
      "x" : 3119,
      "y" : 567,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3123,
      "y" : 571
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3154,
          "y" : 572
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3154,
          "y" : 572
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28964,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3162,
          "y" : 574
        },
        "to" : {
          "x" : 3212,
          "y" : 556
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 3181,
            "y" : 559
          },
          "b" : {
            "x" : 3193,
            "y" : 571
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 3187,
            "y" : 565
          }
        }
      }
    } ]
  }, {
    "id" : 28966,
    "reactomeId" : 10004386,
    "displayName" : "Active PKC theta bound to DAG",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3238,
      "y" : 462
    },
    "minX" : 3181,
    "maxX" : 3318,
    "minY" : 325,
    "maxY" : 504,
    "prop" : {
      "x" : 3181,
      "y" : 444,
      "width" : 115,
      "height" : 36
    },
    "textPosition" : {
      "x" : 3181,
      "y" : 445
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3296,
          "y" : 444
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3296,
          "y" : 444
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28964,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3226,
          "y" : 483
        },
        "to" : {
          "x" : 3212,
          "y" : 504
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3225,
          "y" : 491
        },
        "b" : {
          "x" : 3226,
          "y" : 483
        },
        "c" : {
          "x" : 3219,
          "y" : 487
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3219,
          "y" : 487
        }
      }
    }, {
      "edgeId" : 28971,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3299,
          "y" : 462
        },
        "to" : {
          "x" : 3318,
          "y" : 462
        }
      }, {
        "from" : {
          "x" : 3318,
          "y" : 462
        },
        "to" : {
          "x" : 3318,
          "y" : 328
        }
      }, {
        "from" : {
          "x" : 3318,
          "y" : 328
        },
        "to" : {
          "x" : 3252,
          "y" : 329
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3248,
          "y" : 329
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3248,
          "y" : 329
        }
      }
    } ]
  }, {
    "id" : 28967,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3138,
      "y" : 472
    },
    "minX" : 3118,
    "maxX" : 3212,
    "minY" : 456,
    "maxY" : 504,
    "prop" : {
      "x" : 3118,
      "y" : 457,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3122,
      "y" : 461
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3154,
          "y" : 462
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3154,
          "y" : 462
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28964,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3162,
          "y" : 480
        },
        "to" : {
          "x" : 3212,
          "y" : 504
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 3181,
            "y" : 486
          },
          "b" : {
            "x" : 3193,
            "y" : 498
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 3187,
            "y" : 492
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 3170,
          "y" : 479
        },
        "b" : {
          "x" : 3162,
          "y" : 480
        },
        "c" : {
          "x" : 3167,
          "y" : 487
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3167,
          "y" : 487
        }
      }
    } ]
  }, {
    "id" : 28969,
    "reactomeId" : 10004468,
    "displayName" : "Card11",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2996,
      "y" : 946
    },
    "minX" : 2967,
    "maxX" : 3031,
    "minY" : 905,
    "maxY" : 957,
    "prop" : {
      "x" : 2967,
      "y" : 935,
      "width" : 58,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2969,
      "y" : 935
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3025,
          "y" : 935
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3025,
          "y" : 935
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28968,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3003,
          "y" : 932
        },
        "to" : {
          "x" : 3023,
          "y" : 905
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28970,
    "reactomeId" : 10004470,
    "displayName" : "CARMA1 bound to PDK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3237,
      "y" : 398
    },
    "minX" : 3178,
    "maxX" : 3303,
    "minY" : 353,
    "maxY" : 416,
    "prop" : {
      "x" : 3178,
      "y" : 380,
      "width" : 119,
      "height" : 36
    },
    "textPosition" : {
      "x" : 3176,
      "y" : 381
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3297,
          "y" : 380
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3297,
          "y" : 380
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28968,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28971,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3236,
          "y" : 377
        },
        "to" : {
          "x" : 3236,
          "y" : 353
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28972,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3156,
      "y" : 365
    },
    "minX" : 3136,
    "maxX" : 3236,
    "minY" : 349,
    "maxY" : 380,
    "prop" : {
      "x" : 3136,
      "y" : 350,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3140,
      "y" : 354
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3171,
          "y" : 355
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3171,
          "y" : 355
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28971,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3179,
          "y" : 362
        },
        "to" : {
          "x" : 3236,
          "y" : 353
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28973,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3159,
      "y" : 282
    },
    "minX" : 3139,
    "maxX" : 3236,
    "minY" : 266,
    "maxY" : 307,
    "prop" : {
      "x" : 3139,
      "y" : 267,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3143,
      "y" : 271
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3175,
          "y" : 272
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3175,
          "y" : 272
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28971,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3183,
          "y" : 288
        },
        "to" : {
          "x" : 3236,
          "y" : 307
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3191,
          "y" : 287
        },
        "b" : {
          "x" : 3183,
          "y" : 288
        },
        "c" : {
          "x" : 3188,
          "y" : 294
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3188,
          "y" : 294
        }
      }
    } ]
  }, {
    "id" : 28974,
    "reactomeId" : 10004487,
    "displayName" : "Activated CARMA1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3237,
      "y" : 249
    },
    "minX" : 3177,
    "maxX" : 3304,
    "minY" : 201,
    "maxY" : 307,
    "prop" : {
      "x" : 3177,
      "y" : 238,
      "width" : 121,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3177,
      "y" : 239
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3298,
          "y" : 238
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3298,
          "y" : 238
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28971,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3236,
          "y" : 263
        },
        "to" : {
          "x" : 3236,
          "y" : 307
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3240,
          "y" : 270
        },
        "b" : {
          "x" : 3236,
          "y" : 263
        },
        "c" : {
          "x" : 3232,
          "y" : 270
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3232,
          "y" : 270
        }
      }
    }, {
      "edgeId" : 28975,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3228,
          "y" : 235
        },
        "to" : {
          "x" : 3201,
          "y" : 201
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28976,
    "reactomeId" : 10004485,
    "displayName" : "phospho-Card11",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3108,
      "y" : 227
    },
    "minX" : 3050,
    "maxX" : 3201,
    "minY" : 199,
    "maxY" : 245,
    "prop" : {
      "x" : 3050,
      "y" : 210,
      "width" : 117,
      "height" : 35
    },
    "textPosition" : {
      "x" : 3052,
      "y" : 217
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3167,
          "y" : 210
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3167,
          "y" : 210
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28975,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3170,
          "y" : 210
        },
        "to" : {
          "x" : 3201,
          "y" : 201
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 3179,
            "y" : 199
          },
          "b" : {
            "x" : 3191,
            "y" : 211
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 3185,
            "y" : 205
          }
        }
      }
    } ]
  }, {
    "id" : 28977,
    "reactomeId" : 10004492,
    "displayName" : "CARMA1 trimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3237,
      "y" : 77
    },
    "minX" : 3170,
    "maxX" : 3293,
    "minY" : 60,
    "maxY" : 88,
    "prop" : {
      "x" : 3187,
      "y" : 66,
      "width" : 100,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3187,
      "y" : 67
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3287,
          "y" : 66
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3287,
          "y" : 66
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28975,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28978,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3184,
          "y" : 74
        },
        "to" : {
          "x" : 3170,
          "y" : 74
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28979,
    "reactomeId" : 2685587,
    "displayName" : "Bcl10",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3171,
      "y" : 115
    },
    "minX" : 3148,
    "maxX" : 3200,
    "minY" : 74,
    "maxY" : 126,
    "prop" : {
      "x" : 3148,
      "y" : 104,
      "width" : 46,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3150,
      "y" : 104
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3194,
          "y" : 104
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3194,
          "y" : 104
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28978,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3170,
          "y" : 101
        },
        "to" : {
          "x" : 3170,
          "y" : 74
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28980,
    "reactomeId" : 10004519,
    "displayName" : "Bcl10 bound to CARMA1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 3066,
      "y" : 75
    },
    "minX" : 2995,
    "maxX" : 3123,
    "minY" : 51,
    "maxY" : 93,
    "prop" : {
      "x" : 3016,
      "y" : 57,
      "width" : 101,
      "height" : 36
    },
    "textPosition" : {
      "x" : 3021,
      "y" : 58
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3117,
          "y" : 57
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3117,
          "y" : 57
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28978,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28981,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3013,
          "y" : 75
        },
        "to" : {
          "x" : 2995,
          "y" : 75
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28982,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3045,
      "y" : 137
    },
    "minX" : 2995,
    "maxX" : 3066,
    "minY" : 75,
    "maxY" : 152,
    "prop" : {
      "x" : 3025,
      "y" : 122,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3029,
      "y" : 126
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3060,
          "y" : 127
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3060,
          "y" : 127
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28981,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 3032,
          "y" : 119
        },
        "to" : {
          "x" : 2995,
          "y" : 75
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28983,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2896,
      "y" : 137
    },
    "minX" : 2876,
    "maxX" : 2952,
    "minY" : 75,
    "maxY" : 152,
    "prop" : {
      "x" : 2876,
      "y" : 122,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 2880,
      "y" : 126
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2912,
          "y" : 127
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2912,
          "y" : 127
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28981,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2909,
          "y" : 119
        },
        "to" : {
          "x" : 2952,
          "y" : 75
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2911,
          "y" : 111
        },
        "b" : {
          "x" : 2909,
          "y" : 119
        },
        "c" : {
          "x" : 2917,
          "y" : 117
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2917,
          "y" : 117
        }
      }
    } ]
  }, {
    "id" : 28984,
    "reactomeId" : 10004521,
    "displayName" : "Phosphorylated Bcl10 bound to CARMA1 and RIP2",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2846,
      "y" : 75
    },
    "minX" : 2767,
    "maxX" : 2952,
    "minY" : 44,
    "maxY" : 100,
    "prop" : {
      "x" : 2787,
      "y" : 50,
      "width" : 118,
      "height" : 50
    },
    "textPosition" : {
      "x" : 2787,
      "y" : 51
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2905,
          "y" : 50
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2905,
          "y" : 50
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28981,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2908,
          "y" : 75
        },
        "to" : {
          "x" : 2952,
          "y" : 75
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2915,
          "y" : 71
        },
        "b" : {
          "x" : 2908,
          "y" : 75
        },
        "c" : {
          "x" : 2915,
          "y" : 79
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2915,
          "y" : 79
        }
      }
    }, {
      "edgeId" : 28986,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2784,
          "y" : 73
        },
        "to" : {
          "x" : 2767,
          "y" : 73
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28985,
    "reactomeId" : 9996957,
    "displayName" : "RIPK2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2971,
      "y" : 139
    },
    "minX" : 2950,
    "maxX" : 2999,
    "minY" : 83,
    "maxY" : 150,
    "prop" : {
      "x" : 2950,
      "y" : 128,
      "width" : 43,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2950,
      "y" : 128
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2993,
          "y" : 128
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2993,
          "y" : 128
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28981,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2970,
          "y" : 125
        },
        "to" : {
          "x" : 2970,
          "y" : 91
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2970,
          "y" : 87
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2970,
          "y" : 87
        }
      }
    } ]
  }, {
    "id" : 28987,
    "reactomeId" : 10004498,
    "displayName" : "phospho-Bcl10",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2791,
      "y" : 140
    },
    "minX" : 2753,
    "maxX" : 2835,
    "minY" : 73,
    "maxY" : 155,
    "prop" : {
      "x" : 2753,
      "y" : 126,
      "width" : 76,
      "height" : 29
    },
    "textPosition" : {
      "x" : 2757,
      "y" : 123
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2829,
          "y" : 126
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2829,
          "y" : 126
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28986,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2785,
          "y" : 123
        },
        "to" : {
          "x" : 2767,
          "y" : 73
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 2770,
            "y" : 92
          },
          "b" : {
            "x" : 2782,
            "y" : 104
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2776,
            "y" : 98
          }
        }
      }
    } ]
  }, {
    "id" : 28988,
    "reactomeId" : 10004500,
    "displayName" : "Bcl10 trimer bound to CARMA1 trimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2650,
      "y" : 73
    },
    "minX" : 2563,
    "maxX" : 2722,
    "minY" : 49,
    "maxY" : 91,
    "prop" : {
      "x" : 2584,
      "y" : 55,
      "width" : 132,
      "height" : 36
    },
    "textPosition" : {
      "x" : 2584,
      "y" : 56
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2716,
          "y" : 55
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2716,
          "y" : 55
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28986,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28989,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2581,
          "y" : 73
        },
        "to" : {
          "x" : 2563,
          "y" : 73
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28990,
    "reactomeId" : 10004505,
    "displayName" : "MALT1 trimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2618,
      "y" : 129
    },
    "minX" : 2563,
    "maxX" : 2668,
    "minY" : 73,
    "maxY" : 140,
    "prop" : {
      "x" : 2574,
      "y" : 118,
      "width" : 88,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2574,
      "y" : 119
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2662,
          "y" : 118
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2662,
          "y" : 118
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28989,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2607,
          "y" : 115
        },
        "to" : {
          "x" : 2563,
          "y" : 73
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28991,
    "reactomeId" : 10004507,
    "displayName" : "MALT1 trimer bound to Bcl10 and CARMA1 trimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2426,
      "y" : 75
    },
    "minX" : 2332,
    "maxX" : 2499,
    "minY" : 44,
    "maxY" : 100,
    "prop" : {
      "x" : 2360,
      "y" : 50,
      "width" : 133,
      "height" : 50
    },
    "textPosition" : {
      "x" : 2359,
      "y" : 51
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2493,
          "y" : 50
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2493,
          "y" : 50
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28989,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28992,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2357,
          "y" : 74
        },
        "to" : {
          "x" : 2332,
          "y" : 74
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28993,
    "reactomeId" : 9996713,
    "displayName" : "Traf6",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2368,
      "y" : 134
    },
    "minX" : 2332,
    "maxX" : 2398,
    "minY" : 74,
    "maxY" : 145,
    "prop" : {
      "x" : 2345,
      "y" : 123,
      "width" : 47,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2348,
      "y" : 123
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2392,
          "y" : 123
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2392,
          "y" : 123
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28992,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2361,
          "y" : 120
        },
        "to" : {
          "x" : 2332,
          "y" : 74
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 2340,
            "y" : 91
          },
          "b" : {
            "x" : 2352,
            "y" : 103
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2346,
            "y" : 97
          }
        }
      }
    } ]
  }, {
    "id" : 28994,
    "reactomeId" : 10004509,
    "displayName" : "TRAF6 trimer bound to CBM complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2209,
      "y" : 76
    },
    "minX" : 2074,
    "maxX" : 2281,
    "minY" : 42,
    "maxY" : 94,
    "prop" : {
      "x" : 2144,
      "y" : 58,
      "width" : 131,
      "height" : 36
    },
    "textPosition" : {
      "x" : 2142,
      "y" : 59
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2275,
          "y" : 58
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2275,
          "y" : 58
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28992,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28995,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2141,
          "y" : 74
        },
        "to" : {
          "x" : 2117,
          "y" : 74
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28995,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2141,
          "y" : 59
        },
        "to" : {
          "x" : 2078,
          "y" : 42
        }
      }, {
        "from" : {
          "x" : 2078,
          "y" : 42
        },
        "to" : {
          "x" : 2078,
          "y" : 58
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2078,
          "y" : 62
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2078,
          "y" : 62
        }
      }
    } ]
  }, {
    "id" : 28996,
    "reactomeId" : 9997047,
    "displayName" : "UBE2N:UBE2V1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2052,
      "y" : 165
    },
    "minX" : 2001,
    "maxX" : 2117,
    "minY" : 74,
    "maxY" : 176,
    "prop" : {
      "x" : 2001,
      "y" : 154,
      "width" : 102,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2023,
      "y" : 141
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2103,
          "y" : 154
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2103,
          "y" : 154
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28995,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2059,
          "y" : 151
        },
        "to" : {
          "x" : 2117,
          "y" : 74
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 2082,
            "y" : 106
          },
          "b" : {
            "x" : 2094,
            "y" : 118
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2088,
            "y" : 112
          }
        }
      }
    }, {
      "edgeId" : 28995,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2052,
          "y" : 151
        },
        "to" : {
          "x" : 2052,
          "y" : 74
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 2046,
            "y" : 106
          },
          "b" : {
            "x" : 2058,
            "y" : 118
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2052,
            "y" : 112
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 2048,
          "y" : 144
        },
        "b" : {
          "x" : 2052,
          "y" : 151
        },
        "c" : {
          "x" : 2056,
          "y" : 144
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2056,
          "y" : 144
        }
      }
    } ]
  }, {
    "id" : 28997,
    "reactomeId" : 9997017,
    "displayName" : "K63polyUb",
    "schemaClass" : "Polymer",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 2188,
      "y" : 165
    },
    "minX" : 2117,
    "maxX" : 2225,
    "minY" : 74,
    "maxY" : 176,
    "prop" : {
      "x" : 2152,
      "y" : 154,
      "width" : 73,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2152,
      "y" : 154
    },
    "connectors" : [ {
      "edgeId" : 28995,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2179,
          "y" : 151
        },
        "to" : {
          "x" : 2117,
          "y" : 74
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 2142,
            "y" : 106
          },
          "b" : {
            "x" : 2154,
            "y" : 118
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 2148,
            "y" : 112
          }
        }
      }
    } ]
  }, {
    "id" : 28998,
    "reactomeId" : 10004514,
    "displayName" : "Ub-TRAF6 trimer bound to CBM complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1956,
      "y" : 74
    },
    "minX" : 1680,
    "maxX" : 2052,
    "minY" : 43,
    "maxY" : 323,
    "prop" : {
      "x" : 1900,
      "y" : 49,
      "width" : 113,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1900,
      "y" : 50
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2013,
          "y" : 49
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2013,
          "y" : 49
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28995,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2016,
          "y" : 74
        },
        "to" : {
          "x" : 2052,
          "y" : 74
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2023,
          "y" : 70
        },
        "b" : {
          "x" : 2016,
          "y" : 74
        },
        "c" : {
          "x" : 2023,
          "y" : 78
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2023,
          "y" : 78
        }
      }
    }, {
      "edgeId" : 28999,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1897,
          "y" : 72
        },
        "to" : {
          "x" : 1854,
          "y" : 72
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 29009,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1956,
          "y" : 102
        },
        "to" : {
          "x" : 1959,
          "y" : 299
        }
      }, {
        "from" : {
          "x" : 1959,
          "y" : 299
        },
        "to" : {
          "x" : 1684,
          "y" : 303
        }
      }, {
        "from" : {
          "x" : 1684,
          "y" : 303
        },
        "to" : {
          "x" : 1684,
          "y" : 315
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1684,
          "y" : 319
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1684,
          "y" : 319
        }
      }
    } ]
  }, {
    "id" : 29000,
    "reactomeId" : 10004555,
    "displayName" : "TAB2/TAK1 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1877,
      "y" : 182
    },
    "minX" : 1812,
    "maxX" : 1949,
    "minY" : 72,
    "maxY" : 193,
    "prop" : {
      "x" : 1812,
      "y" : 171,
      "width" : 131,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1813,
      "y" : 172
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1943,
          "y" : 171
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1943,
          "y" : 171
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28999,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1874,
          "y" : 168
        },
        "to" : {
          "x" : 1854,
          "y" : 72
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28999,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1857,
          "y" : 168
        },
        "to" : {
          "x" : 1827,
          "y" : 154
        }
      }, {
        "from" : {
          "x" : 1827,
          "y" : 154
        },
        "to" : {
          "x" : 1827,
          "y" : 88
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1827,
          "y" : 84
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1827,
          "y" : 84
        }
      }
    } ]
  }, {
    "id" : 29001,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1905,
      "y" : 136
    },
    "minX" : 1854,
    "maxX" : 1926,
    "minY" : 72,
    "maxY" : 151,
    "prop" : {
      "x" : 1885,
      "y" : 121,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1889,
      "y" : 125
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1920,
          "y" : 126
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1920,
          "y" : 126
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28999,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1893,
          "y" : 118
        },
        "to" : {
          "x" : 1854,
          "y" : 72
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1867,
            "y" : 89
          },
          "b" : {
            "x" : 1879,
            "y" : 101
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1873,
            "y" : 95
          }
        }
      }
    } ]
  }, {
    "id" : 29002,
    "reactomeId" : 10004547,
    "displayName" : "TAK1/TAB2 complex bound to TRAF6/CBM complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1685,
      "y" : 74
    },
    "minX" : 1590,
    "maxX" : 1792,
    "minY" : 43,
    "maxY" : 178,
    "prop" : {
      "x" : 1618,
      "y" : 49,
      "width" : 135,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1619,
      "y" : 50
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1753,
          "y" : 49
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1753,
          "y" : 49
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28999,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1756,
          "y" : 72
        },
        "to" : {
          "x" : 1792,
          "y" : 72
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1763,
          "y" : 68
        },
        "b" : {
          "x" : 1756,
          "y" : 72
        },
        "c" : {
          "x" : 1763,
          "y" : 76
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1763,
          "y" : 76
        }
      }
    }, {
      "edgeId" : 29004,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1615,
          "y" : 73
        },
        "to" : {
          "x" : 1594,
          "y" : 73
        }
      }, {
        "from" : {
          "x" : 1594,
          "y" : 73
        },
        "to" : {
          "x" : 1594,
          "y" : 170
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1594,
          "y" : 174
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1594,
          "y" : 174
        }
      }
    } ]
  }, {
    "id" : 29003,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1751,
      "y" : 140
    },
    "minX" : 1731,
    "maxX" : 1792,
    "minY" : 72,
    "maxY" : 155,
    "prop" : {
      "x" : 1731,
      "y" : 125,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1735,
      "y" : 129
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1767,
          "y" : 130
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1767,
          "y" : 130
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28999,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1760,
          "y" : 122
        },
        "to" : {
          "x" : 1792,
          "y" : 72
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1770,
            "y" : 91
          },
          "b" : {
            "x" : 1782,
            "y" : 103
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1776,
            "y" : 97
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1760,
          "y" : 114
        },
        "b" : {
          "x" : 1760,
          "y" : 122
        },
        "c" : {
          "x" : 1767,
          "y" : 118
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1767,
          "y" : 118
        }
      }
    } ]
  }, {
    "id" : 29005,
    "reactomeId" : 10004534,
    "displayName" : "CHUK:IKBKB:IKBKG",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1681,
      "y" : 240
    },
    "minX" : 1622,
    "maxX" : 1746,
    "minY" : 186,
    "maxY" : 251,
    "prop" : {
      "x" : 1622,
      "y" : 229,
      "width" : 118,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1623,
      "y" : 230
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1740,
          "y" : 229
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1740,
          "y" : 229
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29004,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1669,
          "y" : 226
        },
        "to" : {
          "x" : 1624,
          "y" : 186
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29006,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1675,
      "y" : 144
    },
    "minX" : 1624,
    "maxX" : 1696,
    "minY" : 128,
    "maxY" : 186,
    "prop" : {
      "x" : 1655,
      "y" : 129,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1659,
      "y" : 133
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1690,
          "y" : 134
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1690,
          "y" : 134
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29004,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1656,
          "y" : 162
        },
        "to" : {
          "x" : 1624,
          "y" : 186
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1634,
            "y" : 168
          },
          "b" : {
            "x" : 1646,
            "y" : 180
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1640,
            "y" : 174
          }
        }
      }
    } ]
  }, {
    "id" : 29007,
    "reactomeId" : 10004536,
    "displayName" : "CHUK:p-S177,S181-IKBKB:IKBKG",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1489,
      "y" : 248
    },
    "minX" : 1427,
    "maxX" : 1647,
    "minY" : 186,
    "maxY" : 331,
    "prop" : {
      "x" : 1427,
      "y" : 230,
      "width" : 125,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1432,
      "y" : 231
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1552,
          "y" : 230
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1552,
          "y" : 230
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29004,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1509,
          "y" : 227
        },
        "to" : {
          "x" : 1561,
          "y" : 186
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1512,
          "y" : 220
        },
        "b" : {
          "x" : 1509,
          "y" : 227
        },
        "c" : {
          "x" : 1517,
          "y" : 226
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1517,
          "y" : 226
        }
      }
    }, {
      "edgeId" : 29009,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1523,
          "y" : 269
        },
        "to" : {
          "x" : 1647,
          "y" : 331
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29008,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1493,
      "y" : 147
    },
    "minX" : 1473,
    "maxX" : 1561,
    "minY" : 131,
    "maxY" : 186,
    "prop" : {
      "x" : 1473,
      "y" : 132,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1477,
      "y" : 136
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1509,
          "y" : 137
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1509,
          "y" : 137
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29004,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1517,
          "y" : 158
        },
        "to" : {
          "x" : 1561,
          "y" : 186
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1533,
            "y" : 166
          },
          "b" : {
            "x" : 1545,
            "y" : 178
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1539,
            "y" : 172
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1525,
          "y" : 158
        },
        "b" : {
          "x" : 1517,
          "y" : 158
        },
        "c" : {
          "x" : 1521,
          "y" : 165
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1521,
          "y" : 165
        }
      }
    } ]
  }, {
    "id" : 29010,
    "reactomeId" : 9997047,
    "displayName" : "UBE2N:UBE2V1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1594,
      "y" : 393
    },
    "minX" : 1543,
    "maxX" : 1757,
    "minY" : 331,
    "maxY" : 404,
    "prop" : {
      "x" : 1543,
      "y" : 382,
      "width" : 102,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1565,
      "y" : 369
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1645,
          "y" : 382
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1645,
          "y" : 382
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29009,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1603,
          "y" : 379
        },
        "to" : {
          "x" : 1647,
          "y" : 331
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 29009,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1622,
          "y" : 379
        },
        "to" : {
          "x" : 1757,
          "y" : 331
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1627,
          "y" : 373
        },
        "b" : {
          "x" : 1622,
          "y" : 379
        },
        "c" : {
          "x" : 1630,
          "y" : 380
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1630,
          "y" : 380
        }
      }
    } ]
  }, {
    "id" : 29011,
    "reactomeId" : 9997017,
    "displayName" : "K63polyUb",
    "schemaClass" : "Polymer",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1560,
      "y" : 332
    },
    "minX" : 1524,
    "maxX" : 1647,
    "minY" : 321,
    "maxY" : 343,
    "prop" : {
      "x" : 1524,
      "y" : 321,
      "width" : 73,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1524,
      "y" : 321
    },
    "connectors" : [ {
      "edgeId" : 29009,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1600,
          "y" : 331
        },
        "to" : {
          "x" : 1647,
          "y" : 331
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29012,
    "reactomeId" : 10004566,
    "displayName" : "CHUK:p-S177,S181-IKBKB:pUb-IKBKG",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1856,
      "y" : 404
    },
    "minX" : 1757,
    "maxX" : 1925,
    "minY" : 331,
    "maxY" : 589,
    "prop" : {
      "x" : 1794,
      "y" : 386,
      "width" : 125,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1801,
      "y" : 373
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1919,
          "y" : 386
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1919,
          "y" : 386
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29009,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1831,
          "y" : 383
        },
        "to" : {
          "x" : 1757,
          "y" : 331
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1823,
          "y" : 382
        },
        "b" : {
          "x" : 1831,
          "y" : 383
        },
        "c" : {
          "x" : 1828,
          "y" : 376
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1828,
          "y" : 376
        }
      }
    }, {
      "edgeId" : 29013,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1856,
          "y" : 425
        },
        "to" : {
          "x" : 1857,
          "y" : 581
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1857,
          "y" : 585
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1857,
          "y" : 585
        }
      }
    } ]
  }, {
    "id" : 29014,
    "reactomeId" : 10001780,
    "displayName" : "IkB(alpha):NF-kB complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1945,
      "y" : 556
    },
    "minX" : 1890,
    "maxX" : 2006,
    "minY" : 532,
    "maxY" : 597,
    "prop" : {
      "x" : 1890,
      "y" : 538,
      "width" : 110,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1888,
      "y" : 539
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2000,
          "y" : 538
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2000,
          "y" : 538
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29013,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1924,
          "y" : 577
        },
        "to" : {
          "x" : 1898,
          "y" : 597
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29015,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1951,
      "y" : 622
    },
    "minX" : 1898,
    "maxX" : 1972,
    "minY" : 597,
    "maxY" : 637,
    "prop" : {
      "x" : 1931,
      "y" : 607,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1935,
      "y" : 611
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1966,
          "y" : 612
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1966,
          "y" : 612
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29013,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1928,
          "y" : 612
        },
        "to" : {
          "x" : 1898,
          "y" : 597
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1907,
            "y" : 598
          },
          "b" : {
            "x" : 1919,
            "y" : 610
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1913,
            "y" : 604
          }
        }
      }
    } ]
  }, {
    "id" : 29016,
    "reactomeId" : 10004571,
    "displayName" : "p-S32,36-IkB-alpha:NF-kB complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1748,
      "y" : 643
    },
    "minX" : 1656,
    "maxX" : 1828,
    "minY" : 597,
    "maxY" : 668,
    "prop" : {
      "x" : 1700,
      "y" : 618,
      "width" : 97,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1703,
      "y" : 619
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1797,
          "y" : 618
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1797,
          "y" : 618
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29013,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1791,
          "y" : 615
        },
        "to" : {
          "x" : 1828,
          "y" : 597
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1795,
          "y" : 608
        },
        "b" : {
          "x" : 1791,
          "y" : 615
        },
        "c" : {
          "x" : 1799,
          "y" : 616
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1799,
          "y" : 616
        }
      }
    }, {
      "edgeId" : 29028,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1697,
          "y" : 642
        },
        "to" : {
          "x" : 1656,
          "y" : 642
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29017,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1764,
      "y" : 562
    },
    "minX" : 1744,
    "maxX" : 1828,
    "minY" : 546,
    "maxY" : 597,
    "prop" : {
      "x" : 1744,
      "y" : 547,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1748,
      "y" : 551
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1780,
          "y" : 552
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1780,
          "y" : 552
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29013,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1788,
          "y" : 573
        },
        "to" : {
          "x" : 1828,
          "y" : 597
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1802,
            "y" : 579
          },
          "b" : {
            "x" : 1814,
            "y" : 591
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1808,
            "y" : 585
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1796,
          "y" : 573
        },
        "b" : {
          "x" : 1788,
          "y" : 573
        },
        "c" : {
          "x" : 1792,
          "y" : 580
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1792,
          "y" : 580
        }
      }
    } ]
  }, {
    "id" : 29019,
    "reactomeId" : 10004369,
    "displayName" : "phospho-Lcp2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1054,
      "y" : 1161
    },
    "minX" : 1004,
    "maxX" : 1130,
    "minY" : 1112,
    "maxY" : 1184,
    "prop" : {
      "x" : 1005,
      "y" : 1138,
      "width" : 99,
      "height" : 46
    },
    "textPosition" : {
      "x" : 1006,
      "y" : 1150
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1104,
          "y" : 1138
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1104,
          "y" : 1138
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29018,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1030,
          "y" : 1135
        },
        "to" : {
          "x" : 1004,
          "y" : 1112
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 29022,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1090,
          "y" : 1135
        },
        "to" : {
          "x" : 1130,
          "y" : 1113
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29020,
    "reactomeId" : 10013302,
    "displayName" : "Fyb1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 962,
      "y" : 1155
    },
    "minX" : 947,
    "maxX" : 1004,
    "minY" : 1112,
    "maxY" : 1166,
    "prop" : {
      "x" : 947,
      "y" : 1144,
      "width" : 31,
      "height" : 22
    },
    "textPosition" : {
      "x" : 948,
      "y" : 1138
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 978,
          "y" : 1144
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 978,
          "y" : 1144
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29018,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 972,
          "y" : 1141
        },
        "to" : {
          "x" : 1004,
          "y" : 1112
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29021,
    "reactomeId" : 10016457,
    "displayName" : "p-SLP-76:ADAP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1003,
      "y" : 1045
    },
    "minX" : 952,
    "maxX" : 1060,
    "minY" : 1028,
    "maxY" : 1056,
    "prop" : {
      "x" : 952,
      "y" : 1034,
      "width" : 102,
      "height" : 22
    },
    "textPosition" : {
      "x" : 953,
      "y" : 1035
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1054,
          "y" : 1034
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1054,
          "y" : 1034
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29018,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29023,
    "reactomeId" : 10008682,
    "displayName" : "Nck1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1169,
      "y" : 1155
    },
    "minX" : 1130,
    "maxX" : 1196,
    "minY" : 1113,
    "maxY" : 1166,
    "prop" : {
      "x" : 1148,
      "y" : 1144,
      "width" : 42,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1149,
      "y" : 1144
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1190,
          "y" : 1144
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1190,
          "y" : 1144
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29022,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1158,
          "y" : 1141
        },
        "to" : {
          "x" : 1130,
          "y" : 1113
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29024,
    "reactomeId" : 10016467,
    "displayName" : "p-SLP-76:NCK1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1130,
      "y" : 1045
    },
    "minX" : 1079,
    "maxX" : 1188,
    "minY" : 1008,
    "maxY" : 1056,
    "prop" : {
      "x" : 1079,
      "y" : 1034,
      "width" : 103,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1081,
      "y" : 1035
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1182,
          "y" : 1034
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1182,
          "y" : 1034
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29022,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 29025,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1141,
          "y" : 1031
        },
        "to" : {
          "x" : 1168,
          "y" : 1008
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29026,
    "reactomeId" : 10012908,
    "displayName" : "PAK1,2,3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1220,
      "y" : 1046
    },
    "minX" : 1168,
    "maxX" : 1252,
    "minY" : 1008,
    "maxY" : 1057,
    "prop" : {
      "x" : 1188,
      "y" : 1035,
      "width" : 64,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1188,
      "y" : 1035
    },
    "connectors" : [ {
      "edgeId" : 29025,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1204,
          "y" : 1029
        },
        "to" : {
          "x" : 1168,
          "y" : 1008
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29027,
    "reactomeId" : 10016469,
    "displayName" : "p-SLP-76:NCK:PAK",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1168,
      "y" : 932
    },
    "minX" : 1107,
    "maxX" : 1235,
    "minY" : 915,
    "maxY" : 943,
    "prop" : {
      "x" : 1107,
      "y" : 921,
      "width" : 122,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1109,
      "y" : 922
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1229,
          "y" : 921
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1229,
          "y" : 921
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29025,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29029,
    "reactomeId" : 10055441,
    "displayName" : "UBE2D2,UBE2D1,(CDC34)",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1624,
      "y" : 726
    },
    "minX" : 1566,
    "maxX" : 1683,
    "minY" : 642,
    "maxY" : 744,
    "prop" : {
      "x" : 1566,
      "y" : 708,
      "width" : 117,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1566,
      "y" : 708
    },
    "connectors" : [ {
      "edgeId" : 29028,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1630,
          "y" : 702
        },
        "to" : {
          "x" : 1656,
          "y" : 642
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 29028,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1618,
          "y" : 702
        },
        "to" : {
          "x" : 1597,
          "y" : 642
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1612,
          "y" : 697
        },
        "b" : {
          "x" : 1618,
          "y" : 702
        },
        "c" : {
          "x" : 1619,
          "y" : 694
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1619,
          "y" : 694
        }
      }
    } ]
  }, {
    "id" : 29030,
    "reactomeId" : 10021592,
    "displayName" : "K48-Ub",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1741,
      "y" : 722
    },
    "minX" : 1656,
    "maxX" : 1769,
    "minY" : 642,
    "maxY" : 733,
    "prop" : {
      "x" : 1713,
      "y" : 711,
      "width" : 56,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1715,
      "y" : 711
    },
    "connectors" : [ {
      "edgeId" : 29028,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1729,
          "y" : 705
        },
        "to" : {
          "x" : 1656,
          "y" : 642
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 1686,
            "y" : 667
          },
          "b" : {
            "x" : 1698,
            "y" : 679
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1692,
            "y" : 673
          }
        }
      }
    } ]
  }, {
    "id" : 29031,
    "reactomeId" : 10028572,
    "displayName" : "CUL1:FBXW11:SKP1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1629,
      "y" : 565
    },
    "minX" : 1579,
    "maxX" : 1685,
    "minY" : 548,
    "maxY" : 642,
    "prop" : {
      "x" : 1579,
      "y" : 554,
      "width" : 100,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1581,
      "y" : 541
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1679,
          "y" : 554
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1679,
          "y" : 554
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29028,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1632,
          "y" : 579
        },
        "to" : {
          "x" : 1656,
          "y" : 642
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 29028,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1624,
          "y" : 579
        },
        "to" : {
          "x" : 1597,
          "y" : 642
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1625,
          "y" : 587
        },
        "b" : {
          "x" : 1624,
          "y" : 579
        },
        "c" : {
          "x" : 1618,
          "y" : 584
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1618,
          "y" : 584
        }
      }
    }, {
      "edgeId" : 29028,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1629,
          "y" : 579
        },
        "to" : {
          "x" : 1629,
          "y" : 626
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1629,
          "y" : 630
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1629,
          "y" : 630
        }
      }
    } ]
  }, {
    "id" : 29032,
    "reactomeId" : 10055426,
    "displayName" : "K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1479,
      "y" : 643
    },
    "minX" : 1414,
    "maxX" : 1597,
    "minY" : 612,
    "maxY" : 668,
    "prop" : {
      "x" : 1414,
      "y" : 618,
      "width" : 130,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1417,
      "y" : 619
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1544,
          "y" : 618
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1544,
          "y" : 618
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29028,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1547,
          "y" : 642
        },
        "to" : {
          "x" : 1597,
          "y" : 642
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1554,
          "y" : 638
        },
        "b" : {
          "x" : 1547,
          "y" : 642
        },
        "c" : {
          "x" : 1554,
          "y" : 646
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1554,
          "y" : 646
        }
      }
    }, {
      "edgeId" : 29033,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29034,
    "reactomeId" : 10001721,
    "displayName" : "NFKB1(1-433):RELA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1276,
      "y" : 645
    },
    "minX" : 1213,
    "maxX" : 1346,
    "minY" : 628,
    "maxY" : 656,
    "prop" : {
      "x" : 1213,
      "y" : 634,
      "width" : 127,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1213,
      "y" : 635
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1340,
          "y" : 634
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1340,
          "y" : 634
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29033,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 29036,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29035,
    "reactomeId" : 9985422,
    "displayName" : "26S proteasome",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1372,
      "y" : 521
    },
    "minX" : 1316,
    "maxX" : 1435,
    "minY" : 504,
    "maxY" : 635,
    "prop" : {
      "x" : 1316,
      "y" : 510,
      "width" : 113,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1316,
      "y" : 511
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1429,
          "y" : 510
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1429,
          "y" : 510
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29033,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1372,
          "y" : 535
        },
        "to" : {
          "x" : 1372,
          "y" : 627
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1372,
          "y" : 631
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1372,
          "y" : 631
        }
      }
    } ]
  }, {
    "id" : 29037,
    "reactomeId" : 10001723,
    "displayName" : "NFKB1(1-433):RELA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1067,
      "y" : 644
    },
    "minX" : 1004,
    "maxX" : 1137,
    "minY" : 627,
    "maxY" : 655,
    "prop" : {
      "x" : 1004,
      "y" : 633,
      "width" : 127,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1004,
      "y" : 634
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1131,
          "y" : 633
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1131,
          "y" : 633
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29036,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29039,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 307,
      "y" : 324
    },
    "minX" : 257,
    "maxX" : 329,
    "minY" : 263,
    "maxY" : 336,
    "prop" : {
      "x" : 287,
      "y" : 312,
      "width" : 41,
      "height" : 24
    },
    "textPosition" : {
      "x" : 290,
      "y" : 313
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 323,
          "y" : 317
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 323,
          "y" : 317
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29038,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 297,
          "y" : 309
        },
        "to" : {
          "x" : 257,
          "y" : 263
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 29040,
    "reactomeId" : 10076113,
    "displayName" : "PTPN22",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 395,
      "y" : 401
    },
    "minX" : 164,
    "maxX" : 433,
    "minY" : 282,
    "maxY" : 756,
    "prop" : {
      "x" : 364,
      "y" : 389,
      "width" : 63,
      "height" : 24
    },
    "textPosition" : {
      "x" : 367,
      "y" : 390
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 427,
          "y" : 389
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 427,
          "y" : 389
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29038,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 395,
          "y" : 386
        },
        "to" : {
          "x" : 395,
          "y" : 290
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 395,
          "y" : 286
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 395,
          "y" : 286
        }
      }
    }, {
      "edgeId" : 29041,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 361,
          "y" : 389
        },
        "to" : {
          "x" : 282,
          "y" : 361
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 353,
          "y" : 390
        },
        "b" : {
          "x" : 361,
          "y" : 389
        },
        "c" : {
          "x" : 356,
          "y" : 383
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 356,
          "y" : 383
        }
      }
    }, {
      "edgeId" : 29043,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 393,
          "y" : 416
        },
        "to" : {
          "x" : 343,
          "y" : 750
        }
      }, {
        "from" : {
          "x" : 343,
          "y" : 750
        },
        "to" : {
          "x" : 172,
          "y" : 752
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 168,
          "y" : 752
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 168,
          "y" : 752
        }
      }
    } ]
  }, {
    "id" : 29042,
    "reactomeId" : 10076732,
    "displayName" : "PTPN22:CSK",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 253,
      "y" : 418
    },
    "minX" : 221,
    "maxX" : 292,
    "minY" : 395,
    "maxY" : 435,
    "prop" : {
      "x" : 221,
      "y" : 401,
      "width" : 65,
      "height" : 34
    },
    "textPosition" : {
      "x" : 223,
      "y" : 400
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 286,
          "y" : 401
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 286,
          "y" : 401
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29041,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29044,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 201,
      "y" : 821
    },
    "minX" : 150,
    "maxX" : 224,
    "minY" : 782,
    "maxY" : 836,
    "prop" : {
      "x" : 180,
      "y" : 806,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 184,
      "y" : 810
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 218,
          "y" : 811
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 218,
          "y" : 811
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29043,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 181,
          "y" : 803
        },
        "to" : {
          "x" : 150,
          "y" : 782
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 29045,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 229,
      "y" : 700
    },
    "minX" : 159,
    "maxX" : 247,
    "minY" : 686,
    "maxY" : 722,
    "prop" : {
      "x" : 212,
      "y" : 687,
      "width" : 34,
      "height" : 26
    },
    "textPosition" : {
      "x" : 219,
      "y" : 689
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 241,
          "y" : 692
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 241,
          "y" : 692
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29043,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 209,
          "y" : 705
        },
        "to" : {
          "x" : 159,
          "y" : 722
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 204,
          "y" : 711
        },
        "b" : {
          "x" : 209,
          "y" : 705
        },
        "c" : {
          "x" : 201,
          "y" : 703
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 201,
          "y" : 703
        }
      }
    } ]
  }, {
    "id" : 29047,
    "reactomeId" : 179856,
    "displayName" : "PI(4,5)P2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 3238,
      "y" : 1203
    },
    "minX" : 3132,
    "maxX" : 3274,
    "minY" : 1187,
    "maxY" : 1231,
    "prop" : {
      "x" : 3203,
      "y" : 1188,
      "width" : 70,
      "height" : 30
    },
    "textPosition" : {
      "x" : 3205,
      "y" : 1192
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3268,
          "y" : 1193
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3268,
          "y" : 1193
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29046,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 3200,
          "y" : 1212
        },
        "to" : {
          "x" : 3132,
          "y" : 1231
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 3194,
          "y" : 1218
        },
        "b" : {
          "x" : 3200,
          "y" : 1212
        },
        "c" : {
          "x" : 3192,
          "y" : 1210
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 3192,
          "y" : 1210
        }
      }
    } ]
  }, {
    "id" : 29048,
    "reactomeId" : 10003158,
    "displayName" : "Pten",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 3019,
      "y" : 1357
    },
    "minX" : 2999,
    "maxX" : 3090,
    "minY" : 1340,
    "maxY" : 1368,
    "prop" : {
      "x" : 2999,
      "y" : 1346,
      "width" : 40,
      "height" : 22
    },
    "textPosition" : {
      "x" : 3000,
      "y" : 1346
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 3039,
          "y" : 1346
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3039,
          "y" : 1346
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29046,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 3042,
          "y" : 1358
        },
        "to" : {
          "x" : 3082,
          "y" : 1360
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 3086,
          "y" : 1360
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 3086,
          "y" : 1360
        }
      }
    } ]
  }, {
    "id" : 29051,
    "reactomeId" : 10099027,
    "displayName" : "PIP3 activates AKT signaling",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 3005,
      "y" : 1467
    },
    "minX" : 2937,
    "maxX" : 3074,
    "minY" : 1439,
    "maxY" : 1495,
    "prop" : {
      "x" : 2937,
      "y" : 1439,
      "width" : 137,
      "height" : 56
    },
    "textPosition" : {
      "x" : 2938,
      "y" : 1445
    },
    "connectors" : [ ]
  }, {
    "id" : 28863,
    "reactomeId" : 9999731,
    "displayName" : "phospho-Pag1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 140,
      "y" : 74
    },
    "minX" : 93,
    "maxX" : 233,
    "minY" : 55,
    "maxY" : 88,
    "prop" : {
      "x" : 93,
      "y" : 61,
      "width" : 95,
      "height" : 27
    },
    "textPosition" : {
      "x" : 107,
      "y" : 57
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 188,
          "y" : 61
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 188,
          "y" : 61
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28862,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 191,
          "y" : 74
        },
        "to" : {
          "x" : 233,
          "y" : 74
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28864,
    "reactomeId" : 10004391,
    "displayName" : "CSK",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 151,
      "y" : 134
    },
    "minX" : 136,
    "maxX" : 282,
    "minY" : 74,
    "maxY" : 361,
    "prop" : {
      "x" : 136,
      "y" : 123,
      "width" : 31,
      "height" : 22
    },
    "textPosition" : {
      "x" : 136,
      "y" : 123
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 167,
          "y" : 123
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 167,
          "y" : 123
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28862,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 166,
          "y" : 120
        },
        "to" : {
          "x" : 233,
          "y" : 74
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 29041,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 157,
          "y" : 148
        },
        "to" : {
          "x" : 282,
          "y" : 361
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 164,
          "y" : 152
        },
        "b" : {
          "x" : 157,
          "y" : 148
        },
        "c" : {
          "x" : 157,
          "y" : 156
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 157,
          "y" : 156
        }
      }
    } ]
  }, {
    "id" : 28865,
    "reactomeId" : 10004393,
    "displayName" : "Csk:p-PAG",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 361,
      "y" : 74
    },
    "minX" : 325,
    "maxX" : 684,
    "minY" : 13,
    "maxY" : 85,
    "prop" : {
      "x" : 325,
      "y" : 63,
      "width" : 73,
      "height" : 22
    },
    "textPosition" : {
      "x" : 326,
      "y" : 64
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 398,
          "y" : 63
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 398,
          "y" : 63
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28862,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28866,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 372,
          "y" : 60
        },
        "to" : {
          "x" : 424,
          "y" : 13
        }
      }, {
        "from" : {
          "x" : 424,
          "y" : 13
        },
        "to" : {
          "x" : 680,
          "y" : 13
        }
      }, {
        "from" : {
          "x" : 680,
          "y" : 13
        },
        "to" : {
          "x" : 680,
          "y" : 55
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 680,
          "y" : 59
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 680,
          "y" : 59
        }
      }
    } ]
  }, {
    "id" : 28867,
    "reactomeId" : 10004343,
    "displayName" : "Antigen-bearing MHC Class II  : TCR complex:CD4:Lck",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 514,
      "y" : 71
    },
    "minX" : 389,
    "maxX" : 645,
    "minY" : 40,
    "maxY" : 242,
    "prop" : {
      "x" : 452,
      "y" : 46,
      "width" : 124,
      "height" : 50
    },
    "textPosition" : {
      "x" : 452,
      "y" : 47
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 576,
          "y" : 46
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 576,
          "y" : 46
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28866,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 579,
          "y" : 71
        },
        "to" : {
          "x" : 645,
          "y" : 71
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28872,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 521,
          "y" : 99
        },
        "to" : {
          "x" : 556,
          "y" : 219
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 527,
          "y" : 105
        },
        "b" : {
          "x" : 521,
          "y" : 99
        },
        "c" : {
          "x" : 519,
          "y" : 107
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 519,
          "y" : 107
        }
      }
    }, {
      "edgeId" : 28875,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 500,
          "y" : 99
        },
        "to" : {
          "x" : 456,
          "y" : 182
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28875,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 449,
          "y" : 91
        },
        "to" : {
          "x" : 393,
          "y" : 111
        }
      }, {
        "from" : {
          "x" : 393,
          "y" : 111
        },
        "to" : {
          "x" : 393,
          "y" : 234
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 393,
          "y" : 238
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 393,
          "y" : 238
        }
      }
    }, {
      "edgeId" : 29038,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 519,
          "y" : 99
        },
        "to" : {
          "x" : 552,
          "y" : 236
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 525,
          "y" : 105
        },
        "b" : {
          "x" : 519,
          "y" : 99
        },
        "c" : {
          "x" : 517,
          "y" : 107
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 517,
          "y" : 107
        }
      }
    } ]
  }, {
    "id" : 28868,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 604,
      "y" : 129
    },
    "minX" : 584,
    "maxX" : 645,
    "minY" : 71,
    "maxY" : 144,
    "prop" : {
      "x" : 584,
      "y" : 114,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 588,
      "y" : 118
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 619,
          "y" : 119
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 619,
          "y" : 119
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28866,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 614,
          "y" : 111
        },
        "to" : {
          "x" : 645,
          "y" : 71
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28869,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 759,
      "y" : 133
    },
    "minX" : 713,
    "maxX" : 781,
    "minY" : 71,
    "maxY" : 148,
    "prop" : {
      "x" : 739,
      "y" : 118,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 743,
      "y" : 122
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 775,
          "y" : 123
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 775,
          "y" : 123
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28866,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 747,
          "y" : 115
        },
        "to" : {
          "x" : 713,
          "y" : 71
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 740,
          "y" : 112
        },
        "b" : {
          "x" : 747,
          "y" : 115
        },
        "c" : {
          "x" : 746,
          "y" : 107
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 746,
          "y" : 107
        }
      }
    } ]
  }, {
    "id" : 28870,
    "reactomeId" : 10004339,
    "displayName" : "Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 829,
      "y" : 72
    },
    "minX" : 713,
    "maxX" : 907,
    "minY" : 34,
    "maxY" : 217,
    "prop" : {
      "x" : 757,
      "y" : 40,
      "width" : 144,
      "height" : 64
    },
    "textPosition" : {
      "x" : 757,
      "y" : 41
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 901,
          "y" : 40
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 901,
          "y" : 40
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28866,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 754,
          "y" : 71
        },
        "to" : {
          "x" : 713,
          "y" : 71
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 747,
          "y" : 75
        },
        "b" : {
          "x" : 754,
          "y" : 71
        },
        "c" : {
          "x" : 747,
          "y" : 67
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 747,
          "y" : 67
        }
      }
    }, {
      "edgeId" : 28872,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 824,
          "y" : 107
        },
        "to" : {
          "x" : 808,
          "y" : 217
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28871,
    "reactomeId" : 10004353,
    "displayName" : "CD45,CD148",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 963,
      "y" : 73
    },
    "minX" : 686,
    "maxX" : 1007,
    "minY" : 0,
    "maxY" : 286,
    "prop" : {
      "x" : 920,
      "y" : 62,
      "width" : 87,
      "height" : 22
    },
    "textPosition" : {
      "x" : 920,
      "y" : 62
    },
    "connectors" : [ {
      "edgeId" : 28866,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 943,
          "y" : 56
        },
        "to" : {
          "x" : 832,
          "y" : 0
        }
      }, {
        "from" : {
          "x" : 832,
          "y" : 0
        },
        "to" : {
          "x" : 688,
          "y" : 67
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 686,
          "y" : 63
        },
        "b" : {
          "x" : 690,
          "y" : 71
        },
        "c" : {
          "x" : 688,
          "y" : 67
        },
        "type" : "STOP",
        "centre" : {
          "x" : 688,
          "y" : 67
        }
      }
    }, {
      "edgeId" : 28872,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 958,
          "y" : 90
        },
        "to" : {
          "x" : 872,
          "y" : 286
        }
      }, {
        "from" : {
          "x" : 872,
          "y" : 286
        },
        "to" : {
          "x" : 696,
          "y" : 286
        }
      }, {
        "from" : {
          "x" : 696,
          "y" : 286
        },
        "to" : {
          "x" : 696,
          "y" : 256
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 696,
          "y" : 252
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 696,
          "y" : 252
        }
      }
    } ]
  }, {
    "id" : 28873,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 753,
      "y" : 174
    },
    "minX" : 732,
    "maxX" : 808,
    "minY" : 158,
    "maxY" : 217,
    "prop" : {
      "x" : 732,
      "y" : 159,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 736,
      "y" : 163
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 770,
          "y" : 164
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 770,
          "y" : 164
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28872,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 772,
          "y" : 192
        },
        "to" : {
          "x" : 808,
          "y" : 217
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 28874,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 611,
      "y" : 170
    },
    "minX" : 552,
    "maxX" : 626,
    "minY" : 154,
    "maxY" : 236,
    "prop" : {
      "x" : 598,
      "y" : 155,
      "width" : 27,
      "height" : 30
    },
    "textPosition" : {
      "x" : 602,
      "y" : 159
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 620,
          "y" : 160
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 620,
          "y" : 160
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28872,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 595,
          "y" : 182
        },
        "to" : {
          "x" : 556,
          "y" : 219
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 593,
          "y" : 190
        },
        "b" : {
          "x" : 595,
          "y" : 182
        },
        "c" : {
          "x" : 587,
          "y" : 184
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 587,
          "y" : 184
        }
      }
    }, {
      "edgeId" : 29038,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 595,
          "y" : 185
        },
        "to" : {
          "x" : 552,
          "y" : 236
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 594,
          "y" : 193
        },
        "b" : {
          "x" : 595,
          "y" : 185
        },
        "c" : {
          "x" : 587,
          "y" : 188
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 587,
          "y" : 188
        }
      }
    } ]
  }, {
    "id" : 28876,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 495,
      "y" : 203
    },
    "minX" : 456,
    "maxX" : 516,
    "minY" : 182,
    "maxY" : 218,
    "prop" : {
      "x" : 475,
      "y" : 188,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 479,
      "y" : 192
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 510,
          "y" : 193
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 510,
          "y" : 193
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28875,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 472,
          "y" : 192
        },
        "to" : {
          "x" : 456,
          "y" : 182
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28877,
    "reactomeId" : 10004253,
    "displayName" : "Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 81,
      "y" : 251
    },
    "minX" : 3,
    "maxX" : 361,
    "minY" : 206,
    "maxY" : 755,
    "prop" : {
      "x" : 22,
      "y" : 212,
      "width" : 118,
      "height" : 78
    },
    "textPosition" : {
      "x" : 21,
      "y" : 213
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 140,
          "y" : 212
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 140,
          "y" : 212
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28875,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 143,
          "y" : 250
        },
        "to" : {
          "x" : 361,
          "y" : 250
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 150,
          "y" : 246
        },
        "b" : {
          "x" : 143,
          "y" : 250
        },
        "c" : {
          "x" : 150,
          "y" : 254
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 150,
          "y" : 254
        }
      }
    }, {
      "edgeId" : 28879,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 102,
          "y" : 293
        },
        "to" : {
          "x" : 127,
          "y" : 333
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28879,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 86,
          "y" : 293
        },
        "to" : {
          "x" : 98,
          "y" : 364
        }
      }, {
        "from" : {
          "x" : 98,
          "y" : 364
        },
        "to" : {
          "x" : 111,
          "y" : 364
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 115,
          "y" : 365
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 115,
          "y" : 365
        }
      }
    }, {
      "edgeId" : 28886,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 45,
          "y" : 293
        },
        "to" : {
          "x" : 3,
          "y" : 337
        }
      }, {
        "from" : {
          "x" : 3,
          "y" : 337
        },
        "to" : {
          "x" : 7,
          "y" : 752
        }
      }, {
        "from" : {
          "x" : 7,
          "y" : 752
        },
        "to" : {
          "x" : 115,
          "y" : 751
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 119,
          "y" : 751
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 119,
          "y" : 751
        }
      }
    }, {
      "edgeId" : 29038,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 143,
          "y" : 255
        },
        "to" : {
          "x" : 257,
          "y" : 263
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28878,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 335,
      "y" : 194
    },
    "minX" : 315,
    "maxX" : 361,
    "minY" : 178,
    "maxY" : 250,
    "prop" : {
      "x" : 315,
      "y" : 179,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 319,
      "y" : 183
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 351,
          "y" : 184
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 351,
          "y" : 184
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28875,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 341,
          "y" : 212
        },
        "to" : {
          "x" : 361,
          "y" : 250
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 348,
          "y" : 216
        },
        "b" : {
          "x" : 341,
          "y" : 212
        },
        "c" : {
          "x" : 341,
          "y" : 220
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 341,
          "y" : 220
        }
      }
    } ]
  }, {
    "id" : 28880,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 176,
      "y" : 292
    },
    "minX" : 127,
    "maxX" : 197,
    "minY" : 276,
    "maxY" : 333,
    "prop" : {
      "x" : 156,
      "y" : 277,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 160,
      "y" : 281
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 191,
          "y" : 282
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 191,
          "y" : 282
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28879,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 158,
          "y" : 310
        },
        "to" : {
          "x" : 127,
          "y" : 333
        }
      } ],
      "stoichiometry" : {
        "value" : 20,
        "shape" : {
          "a" : {
            "x" : 136,
            "y" : 315
          },
          "b" : {
            "x" : 148,
            "y" : 327
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 142,
            "y" : 321
          }
        }
      }
    } ]
  }, {
    "id" : 28881,
    "reactomeId" : 10004283,
    "displayName" : "Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 83,
      "y" : 477
    },
    "minX" : 18,
    "maxX" : 154,
    "minY" : 400,
    "maxY" : 534,
    "prop" : {
      "x" : 18,
      "y" : 438,
      "width" : 130,
      "height" : 78
    },
    "textPosition" : {
      "x" : 24,
      "y" : 439
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 148,
          "y" : 438
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 148,
          "y" : 438
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28879,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 105,
          "y" : 435
        },
        "to" : {
          "x" : 127,
          "y" : 400
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 105,
          "y" : 427
        },
        "b" : {
          "x" : 105,
          "y" : 435
        },
        "c" : {
          "x" : 112,
          "y" : 431
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 112,
          "y" : 431
        }
      }
    }, {
      "edgeId" : 28883,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 94,
          "y" : 519
        },
        "to" : {
          "x" : 100,
          "y" : 534
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28882,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 187,
      "y" : 453
    },
    "minX" : 127,
    "maxX" : 209,
    "minY" : 400,
    "maxY" : 468,
    "prop" : {
      "x" : 167,
      "y" : 438,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 171,
      "y" : 442
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 203,
          "y" : 443
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 203,
          "y" : 443
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28879,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 170,
          "y" : 435
        },
        "to" : {
          "x" : 127,
          "y" : 400
        }
      } ],
      "stoichiometry" : {
        "value" : 20,
        "shape" : {
          "a" : {
            "x" : 142,
            "y" : 411
          },
          "b" : {
            "x" : 154,
            "y" : 423
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 148,
            "y" : 417
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 162,
          "y" : 434
        },
        "b" : {
          "x" : 170,
          "y" : 435
        },
        "c" : {
          "x" : 167,
          "y" : 428
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 167,
          "y" : 428
        }
      }
    } ]
  }, {
    "id" : 28884,
    "reactomeId" : 10004290,
    "displayName" : "ZAP70",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 165,
      "y" : 541
    },
    "minX" : 100,
    "maxX" : 196,
    "minY" : 524,
    "maxY" : 552,
    "prop" : {
      "x" : 140,
      "y" : 530,
      "width" : 50,
      "height" : 22
    },
    "textPosition" : {
      "x" : 140,
      "y" : 530
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 190,
          "y" : 530
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 190,
          "y" : 530
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28883,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 137,
          "y" : 538
        },
        "to" : {
          "x" : 100,
          "y" : 534
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28885,
    "reactomeId" : 10004292,
    "displayName" : "ZAP-70 bound to phosphorylated ITAM motifs",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 89,
      "y" : 647
    },
    "minX" : 32,
    "maxX" : 159,
    "minY" : 616,
    "maxY" : 722,
    "prop" : {
      "x" : 32,
      "y" : 622,
      "width" : 114,
      "height" : 50
    },
    "textPosition" : {
      "x" : 30,
      "y" : 623
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 146,
          "y" : 622
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 146,
          "y" : 622
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28883,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28886,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 105,
          "y" : 675
        },
        "to" : {
          "x" : 132,
          "y" : 712
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 29043,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 112,
          "y" : 675
        },
        "to" : {
          "x" : 159,
          "y" : 722
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 120,
          "y" : 677
        },
        "b" : {
          "x" : 112,
          "y" : 675
        },
        "c" : {
          "x" : 114,
          "y" : 683
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 114,
          "y" : 683
        }
      }
    } ]
  }, {
    "id" : 28887,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 171,
      "y" : 675
    },
    "minX" : 132,
    "maxX" : 192,
    "minY" : 662,
    "maxY" : 712,
    "prop" : {
      "x" : 151,
      "y" : 663,
      "width" : 40,
      "height" : 25
    },
    "textPosition" : {
      "x" : 155,
      "y" : 665
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 186,
          "y" : 668
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 186,
          "y" : 668
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28886,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 157,
          "y" : 691
        },
        "to" : {
          "x" : 132,
          "y" : 712
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28888,
    "reactomeId" : 10004297,
    "displayName" : "phospho tyrosine ZAP-70",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 81,
      "y" : 911
    },
    "minX" : 25,
    "maxX" : 150,
    "minY" : 782,
    "maxY" : 1009,
    "prop" : {
      "x" : 25,
      "y" : 893,
      "width" : 112,
      "height" : 36
    },
    "textPosition" : {
      "x" : 27,
      "y" : 894
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 137,
          "y" : 893
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 137,
          "y" : 893
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28886,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 88,
          "y" : 890
        },
        "to" : {
          "x" : 132,
          "y" : 784
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 87,
          "y" : 882
        },
        "b" : {
          "x" : 88,
          "y" : 890
        },
        "c" : {
          "x" : 94,
          "y" : 885
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 94,
          "y" : 885
        }
      }
    }, {
      "edgeId" : 28890,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 95,
          "y" : 932
        },
        "to" : {
          "x" : 127,
          "y" : 967
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28890,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 83,
          "y" : 932
        },
        "to" : {
          "x" : 94,
          "y" : 1004
        }
      }, {
        "from" : {
          "x" : 94,
          "y" : 1004
        },
        "to" : {
          "x" : 111,
          "y" : 1005
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 115,
          "y" : 1005
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 115,
          "y" : 1005
        }
      }
    }, {
      "edgeId" : 29043,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 90,
          "y" : 890
        },
        "to" : {
          "x" : 150,
          "y" : 782
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28889,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 188,
      "y" : 876
    },
    "minX" : 132,
    "maxX" : 210,
    "minY" : 784,
    "maxY" : 891,
    "prop" : {
      "x" : 168,
      "y" : 861,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 172,
      "y" : 865
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 204,
          "y" : 866
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 204,
          "y" : 866
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28886,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 178,
          "y" : 858
        },
        "to" : {
          "x" : 132,
          "y" : 784
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 171,
          "y" : 854
        },
        "b" : {
          "x" : 178,
          "y" : 858
        },
        "c" : {
          "x" : 178,
          "y" : 850
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 178,
          "y" : 850
        }
      }
    } ]
  }, {
    "id" : 28891,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 191,
      "y" : 926
    },
    "minX" : 127,
    "maxX" : 212,
    "minY" : 910,
    "maxY" : 967,
    "prop" : {
      "x" : 171,
      "y" : 911,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 175,
      "y" : 915
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 206,
          "y" : 916
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 206,
          "y" : 916
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28890,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 168,
          "y" : 938
        },
        "to" : {
          "x" : 127,
          "y" : 967
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28892,
    "reactomeId" : 10004305,
    "displayName" : "Activated ZAP-70",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 90,
      "y" : 1191
    },
    "minX" : 0,
    "maxX" : 301,
    "minY" : 1089,
    "maxY" : 1729,
    "prop" : {
      "x" : 32,
      "y" : 1180,
      "width" : 116,
      "height" : 22
    },
    "textPosition" : {
      "x" : 32,
      "y" : 1181
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 148,
          "y" : 1180
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 148,
          "y" : 1180
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28890,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 93,
          "y" : 1177
        },
        "to" : {
          "x" : 127,
          "y" : 1089
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 92,
          "y" : 1169
        },
        "b" : {
          "x" : 93,
          "y" : 1177
        },
        "c" : {
          "x" : 99,
          "y" : 1172
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 99,
          "y" : 1172
        }
      }
    }, {
      "edgeId" : 28894,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 29,
          "y" : 1190
        },
        "to" : {
          "x" : 0,
          "y" : 1190
        }
      }, {
        "from" : {
          "x" : 0,
          "y" : 1190
        },
        "to" : {
          "x" : 32,
          "y" : 1312
        }
      }, {
        "from" : {
          "x" : 32,
          "y" : 1312
        },
        "to" : {
          "x" : 64,
          "y" : 1313
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 68,
          "y" : 1313
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 68,
          "y" : 1313
        }
      }
    }, {
      "edgeId" : 28905,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 105,
          "y" : 1205
        },
        "to" : {
          "x" : 296,
          "y" : 1341
        }
      }, {
        "from" : {
          "x" : 296,
          "y" : 1341
        },
        "to" : {
          "x" : 297,
          "y" : 1721
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 297,
          "y" : 1725
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 297,
          "y" : 1725
        }
      }
    } ]
  }, {
    "id" : 28893,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 192,
      "y" : 1113
    },
    "minX" : 127,
    "maxX" : 214,
    "minY" : 1089,
    "maxY" : 1128,
    "prop" : {
      "x" : 172,
      "y" : 1098,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 176,
      "y" : 1102
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 208,
          "y" : 1103
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 208,
          "y" : 1103
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28890,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 169,
          "y" : 1105
        },
        "to" : {
          "x" : 127,
          "y" : 1089
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 161,
          "y" : 1106
        },
        "b" : {
          "x" : 169,
          "y" : 1105
        },
        "c" : {
          "x" : 164,
          "y" : 1099
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 164,
          "y" : 1099
        }
      }
    } ]
  }, {
    "id" : 28895,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 135,
      "y" : 1265
    },
    "minX" : 80,
    "maxX" : 156,
    "minY" : 1249,
    "maxY" : 1286,
    "prop" : {
      "x" : 115,
      "y" : 1250,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 119,
      "y" : 1254
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 150,
          "y" : 1255
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 150,
          "y" : 1255
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28894,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 112,
          "y" : 1272
        },
        "to" : {
          "x" : 80,
          "y" : 1286
        }
      } ],
      "stoichiometry" : {
        "value" : 5,
        "shape" : {
          "a" : {
            "x" : 90,
            "y" : 1273
          },
          "b" : {
            "x" : 102,
            "y" : 1285
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 96,
            "y" : 1279
          }
        }
      }
    } ]
  }, {
    "id" : 28896,
    "reactomeId" : 10004407,
    "displayName" : "Lat",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 80,
      "y" : 1241
    },
    "minX" : 65,
    "maxX" : 102,
    "minY" : 1224,
    "maxY" : 1286,
    "prop" : {
      "x" : 65,
      "y" : 1230,
      "width" : 31,
      "height" : 22
    },
    "textPosition" : {
      "x" : 67,
      "y" : 1230
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 96,
          "y" : 1230
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 96,
          "y" : 1230
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28894,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 80,
          "y" : 1255
        },
        "to" : {
          "x" : 80,
          "y" : 1286
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28897,
    "reactomeId" : 10004330,
    "displayName" : "phospho-Lat",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 81,
      "y" : 1427
    },
    "minX" : 18,
    "maxX" : 1934,
    "minY" : 1343,
    "maxY" : 1704,
    "prop" : {
      "x" : 42,
      "y" : 1410,
      "width" : 79,
      "height" : 34
    },
    "textPosition" : {
      "x" : 48,
      "y" : 1410
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 121,
          "y" : 1410
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 121,
          "y" : 1410
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28894,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 80,
          "y" : 1407
        },
        "to" : {
          "x" : 80,
          "y" : 1343
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 76,
          "y" : 1400
        },
        "b" : {
          "x" : 80,
          "y" : 1407
        },
        "c" : {
          "x" : 84,
          "y" : 1400
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 84,
          "y" : 1400
        }
      }
    }, {
      "edgeId" : 28899,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 81,
          "y" : 1447
        },
        "to" : {
          "x" : 81,
          "y" : 1485
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28915,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 71,
          "y" : 1447
        },
        "to" : {
          "x" : 18,
          "y" : 1537
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28924,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 124,
          "y" : 1432
        },
        "to" : {
          "x" : 1934,
          "y" : 1704
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 131,
          "y" : 1429
        },
        "b" : {
          "x" : 124,
          "y" : 1432
        },
        "c" : {
          "x" : 130,
          "y" : 1437
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 130,
          "y" : 1437
        }
      }
    } ]
  }, {
    "id" : 28898,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 144,
      "y" : 1392
    },
    "minX" : 80,
    "maxX" : 166,
    "minY" : 1343,
    "maxY" : 1407,
    "prop" : {
      "x" : 124,
      "y" : 1377,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 128,
      "y" : 1381
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 160,
          "y" : 1382
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 160,
          "y" : 1382
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28894,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 124,
          "y" : 1374
        },
        "to" : {
          "x" : 80,
          "y" : 1343
        }
      } ],
      "stoichiometry" : {
        "value" : 5,
        "shape" : {
          "a" : {
            "x" : 96,
            "y" : 1352
          },
          "b" : {
            "x" : 108,
            "y" : 1364
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 102,
            "y" : 1358
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 116,
          "y" : 1373
        },
        "b" : {
          "x" : 124,
          "y" : 1374
        },
        "c" : {
          "x" : 121,
          "y" : 1367
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 121,
          "y" : 1367
        }
      }
    } ]
  }, {
    "id" : 28900,
    "reactomeId" : 10004359,
    "displayName" : "Grap2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 153,
      "y" : 1456
    },
    "minX" : 81,
    "maxX" : 184,
    "minY" : 1439,
    "maxY" : 1485,
    "prop" : {
      "x" : 129,
      "y" : 1445,
      "width" : 49,
      "height" : 22
    },
    "textPosition" : {
      "x" : 130,
      "y" : 1445
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 178,
          "y" : 1445
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 178,
          "y" : 1445
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28899,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 126,
          "y" : 1465
        },
        "to" : {
          "x" : 81,
          "y" : 1485
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28901,
    "reactomeId" : 10004361,
    "displayName" : "GADS:p-5Y-LAT",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 82,
      "y" : 1589
    },
    "minX" : 30,
    "maxX" : 142,
    "minY" : 1572,
    "maxY" : 1667,
    "prop" : {
      "x" : 30,
      "y" : 1578,
      "width" : 104,
      "height" : 22
    },
    "textPosition" : {
      "x" : 33,
      "y" : 1579
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 134,
          "y" : 1578
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 134,
          "y" : 1578
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28899,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28902,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 90,
          "y" : 1603
        },
        "to" : {
          "x" : 142,
          "y" : 1667
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28903,
    "reactomeId" : 430203,
    "displayName" : "SLP-76",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 200,
      "y" : 1619
    },
    "minX" : 142,
    "maxX" : 225,
    "minY" : 1602,
    "maxY" : 1667,
    "prop" : {
      "x" : 181,
      "y" : 1608,
      "width" : 38,
      "height" : 22
    },
    "textPosition" : {
      "x" : 183,
      "y" : 1602
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 219,
          "y" : 1608
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 219,
          "y" : 1608
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28902,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 186,
          "y" : 1633
        },
        "to" : {
          "x" : 142,
          "y" : 1667
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28904,
    "reactomeId" : 10004364,
    "displayName" : "SLP-76 bound to Gads:LAT",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 143,
      "y" : 1793
    },
    "minX" : 88,
    "maxX" : 241,
    "minY" : 1737,
    "maxY" : 1811,
    "prop" : {
      "x" : 88,
      "y" : 1775,
      "width" : 111,
      "height" : 36
    },
    "textPosition" : {
      "x" : 86,
      "y" : 1776
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 199,
          "y" : 1775
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 199,
          "y" : 1775
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28902,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28905,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 174,
          "y" : 1772
        },
        "to" : {
          "x" : 241,
          "y" : 1737
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28906,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 189,
      "y" : 1695
    },
    "minX" : 169,
    "maxX" : 241,
    "minY" : 1679,
    "maxY" : 1737,
    "prop" : {
      "x" : 169,
      "y" : 1680,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 173,
      "y" : 1684
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 204,
          "y" : 1685
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 204,
          "y" : 1685
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28905,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 207,
          "y" : 1713
        },
        "to" : {
          "x" : 241,
          "y" : 1737
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 218,
            "y" : 1719
          },
          "b" : {
            "x" : 230,
            "y" : 1731
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 224,
            "y" : 1725
          }
        }
      }
    } ]
  }, {
    "id" : 28907,
    "reactomeId" : 10004371,
    "displayName" : "p-Y113,128,145-SLP-76:GADS:LAT",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 402,
      "y" : 1789
    },
    "minX" : 332,
    "maxX" : 1846,
    "minY" : 1715,
    "maxY" : 1885,
    "prop" : {
      "x" : 337,
      "y" : 1768,
      "width" : 131,
      "height" : 43
    },
    "textPosition" : {
      "x" : 346,
      "y" : 1776
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 468,
          "y" : 1768
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 468,
          "y" : 1768
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28905,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 373,
          "y" : 1765
        },
        "to" : {
          "x" : 332,
          "y" : 1737
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 365,
          "y" : 1764
        },
        "b" : {
          "x" : 373,
          "y" : 1765
        },
        "c" : {
          "x" : 370,
          "y" : 1758
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 370,
          "y" : 1758
        }
      }
    }, {
      "edgeId" : 28909,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 471,
          "y" : 1788
        },
        "to" : {
          "x" : 501,
          "y" : 1788
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28912,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 417,
          "y" : 1765
        },
        "to" : {
          "x" : 457,
          "y" : 1715
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28927,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 435,
          "y" : 1814
        },
        "to" : {
          "x" : 551,
          "y" : 1885
        }
      }, {
        "from" : {
          "x" : 551,
          "y" : 1885
        },
        "to" : {
          "x" : 1846,
          "y" : 1872
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 443,
          "y" : 1814
        },
        "b" : {
          "x" : 435,
          "y" : 1814
        },
        "c" : {
          "x" : 439,
          "y" : 1821
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 439,
          "y" : 1821
        }
      }
    } ]
  }, {
    "id" : 28908,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 390,
      "y" : 1707
    },
    "minX" : 332,
    "maxX" : 412,
    "minY" : 1691,
    "maxY" : 1737,
    "prop" : {
      "x" : 370,
      "y" : 1692,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 374,
      "y" : 1696
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 406,
          "y" : 1697
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 406,
          "y" : 1697
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28905,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 367,
          "y" : 1717
        },
        "to" : {
          "x" : 332,
          "y" : 1737
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 343,
            "y" : 1721
          },
          "b" : {
            "x" : 355,
            "y" : 1733
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 349,
            "y" : 1727
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 363,
          "y" : 1724
        },
        "b" : {
          "x" : 367,
          "y" : 1717
        },
        "c" : {
          "x" : 359,
          "y" : 1717
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 359,
          "y" : 1717
        }
      }
    } ]
  }, {
    "id" : 28910,
    "reactomeId" : 10004425,
    "displayName" : "ITK",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 485,
      "y" : 1752
    },
    "minX" : 464,
    "maxX" : 512,
    "minY" : 1733,
    "maxY" : 1788,
    "prop" : {
      "x" : 464,
      "y" : 1739,
      "width" : 42,
      "height" : 26
    },
    "textPosition" : {
      "x" : 472,
      "y" : 1741
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 506,
          "y" : 1739
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 506,
          "y" : 1739
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28909,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 490,
          "y" : 1768
        },
        "to" : {
          "x" : 501,
          "y" : 1788
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28911,
    "reactomeId" : 10004427,
    "displayName" : "ITK:p-Y113,128,145-SLP-76:GADS:LAT",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 605,
      "y" : 1796
    },
    "minX" : 556,
    "maxX" : 660,
    "minY" : 1765,
    "maxY" : 1821,
    "prop" : {
      "x" : 556,
      "y" : 1771,
      "width" : 98,
      "height" : 50
    },
    "textPosition" : {
      "x" : 560,
      "y" : 1772
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 654,
          "y" : 1771
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 654,
          "y" : 1771
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28909,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28913,
    "reactomeId" : 10004321,
    "displayName" : "PLCG1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 392,
      "y" : 1652
    },
    "minX" : 18,
    "maxX" : 457,
    "minY" : 1537,
    "maxY" : 1715,
    "prop" : {
      "x" : 369,
      "y" : 1641,
      "width" : 47,
      "height" : 22
    },
    "textPosition" : {
      "x" : 369,
      "y" : 1641
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 416,
          "y" : 1641
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 416,
          "y" : 1641
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28912,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 403,
          "y" : 1666
        },
        "to" : {
          "x" : 457,
          "y" : 1715
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28915,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 366,
          "y" : 1644
        },
        "to" : {
          "x" : 18,
          "y" : 1537
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28914,
    "reactomeId" : 10004412,
    "displayName" : "PLCG1:p-3Y-SLP-76:Gads:LAT",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 735,
      "y" : 1791
    },
    "minX" : 678,
    "maxX" : 798,
    "minY" : 1767,
    "maxY" : 1809,
    "prop" : {
      "x" : 678,
      "y" : 1773,
      "width" : 114,
      "height" : 36
    },
    "textPosition" : {
      "x" : 681,
      "y" : 1774
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 792,
          "y" : 1773
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 792,
          "y" : 1773
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28912,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28916,
    "reactomeId" : 10004332,
    "displayName" : "PLCG1:p-5Y-LAT",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 74,
      "y" : 1741
    },
    "minX" : 19,
    "maxX" : 135,
    "minY" : 1724,
    "maxY" : 1752,
    "prop" : {
      "x" : 19,
      "y" : 1730,
      "width" : 110,
      "height" : 22
    },
    "textPosition" : {
      "x" : 22,
      "y" : 1731
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 129,
          "y" : 1730
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 129,
          "y" : 1730
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28915,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28918,
    "reactomeId" : 10004414,
    "displayName" : "PLC-gamma1 bound to LAT or SLP-76",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 903,
      "y" : 1792
    },
    "minX" : 837,
    "maxX" : 1053,
    "minY" : 1748,
    "maxY" : 1810,
    "prop" : {
      "x" : 837,
      "y" : 1774,
      "width" : 133,
      "height" : 36
    },
    "textPosition" : {
      "x" : 836,
      "y" : 1774
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 28917,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 964,
          "y" : 1768
        },
        "to" : {
          "x" : 1053,
          "y" : 1748
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28919,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 997,
      "y" : 1716
    },
    "minX" : 977,
    "maxX" : 1053,
    "minY" : 1700,
    "maxY" : 1748,
    "prop" : {
      "x" : 977,
      "y" : 1701,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 981,
      "y" : 1705
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1012,
          "y" : 1706
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1012,
          "y" : 1706
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28917,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1020,
          "y" : 1727
        },
        "to" : {
          "x" : 1053,
          "y" : 1748
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 1030,
            "y" : 1731
          },
          "b" : {
            "x" : 1042,
            "y" : 1743
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1036,
            "y" : 1737
          }
        }
      }
    } ]
  }, {
    "id" : 28920,
    "reactomeId" : 10004422,
    "displayName" : "Phosphorylated PLC-gamma1 bound to LAT or SLP-76",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1231,
      "y" : 1783
    },
    "minX" : 1100,
    "maxX" : 1296,
    "minY" : 1748,
    "maxY" : 1815,
    "prop" : {
      "x" : 1166,
      "y" : 1751,
      "width" : 130,
      "height" : 64
    },
    "textPosition" : {
      "x" : 1175,
      "y" : 1751
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "connectors" : [ {
      "edgeId" : 28917,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1160,
          "y" : 1765
        },
        "to" : {
          "x" : 1100,
          "y" : 1748
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1152,
          "y" : 1767
        },
        "b" : {
          "x" : 1160,
          "y" : 1765
        },
        "c" : {
          "x" : 1154,
          "y" : 1759
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1154,
          "y" : 1759
        }
      }
    } ]
  }, {
    "id" : 28921,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1176,
      "y" : 1719
    },
    "minX" : 1100,
    "maxX" : 1198,
    "minY" : 1703,
    "maxY" : 1748,
    "prop" : {
      "x" : 1156,
      "y" : 1704,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1160,
      "y" : 1708
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1192,
          "y" : 1709
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1192,
          "y" : 1709
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28917,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1153,
          "y" : 1726
        },
        "to" : {
          "x" : 1100,
          "y" : 1748
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 1120,
            "y" : 1731
          },
          "b" : {
            "x" : 1132,
            "y" : 1743
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1126,
            "y" : 1737
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1148,
          "y" : 1732
        },
        "b" : {
          "x" : 1153,
          "y" : 1726
        },
        "c" : {
          "x" : 1145,
          "y" : 1725
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1145,
          "y" : 1725
        }
      }
    } ]
  }, {
    "id" : 28922,
    "reactomeId" : 10004429,
    "displayName" : "ZAP-70 and ITK tyrosine kinases",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1076,
      "y" : 1813
    },
    "minX" : 1021,
    "maxX" : 1132,
    "minY" : 1756,
    "maxY" : 1831,
    "prop" : {
      "x" : 1021,
      "y" : 1795,
      "width" : 111,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1021,
      "y" : 1795
    },
    "connectors" : [ {
      "edgeId" : 28917,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1075,
          "y" : 1789
        },
        "to" : {
          "x" : 1075,
          "y" : 1764
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1075,
          "y" : 1760
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1075,
          "y" : 1760
        }
      }
    } ]
  }, {
    "id" : 28923,
    "reactomeId" : 10004434,
    "displayName" : "Cd101",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1073,
      "y" : 1631
    },
    "minX" : 1048,
    "maxX" : 1104,
    "minY" : 1614,
    "maxY" : 1739,
    "prop" : {
      "x" : 1048,
      "y" : 1620,
      "width" : 50,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1049,
      "y" : 1620
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1098,
          "y" : 1620
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1098,
          "y" : 1620
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28917,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1073,
          "y" : 1645
        },
        "to" : {
          "x" : 1075,
          "y" : 1739
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1071,
          "y" : 1739
        },
        "b" : {
          "x" : 1079,
          "y" : 1739
        },
        "c" : {
          "x" : 1075,
          "y" : 1739
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1075,
          "y" : 1739
        }
      }
    } ]
  }, {
    "id" : 28925,
    "reactomeId" : 10004418,
    "displayName" : "phosphorylated PLC-gamma1 bound to LAT",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1831,
      "y" : 1794
    },
    "minX" : 1766,
    "maxX" : 1903,
    "minY" : 1763,
    "maxY" : 1819,
    "prop" : {
      "x" : 1766,
      "y" : 1769,
      "width" : 131,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1776,
      "y" : 1770
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1897,
          "y" : 1769
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1897,
          "y" : 1769
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28924,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 28926,
    "reactomeId" : 10004416,
    "displayName" : "phospho-p-Y771,Y783,Y1254-PLCG1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2026,
      "y" : 1801
    },
    "minX" : 1846,
    "maxX" : 2188,
    "minY" : 1704,
    "maxY" : 1872,
    "prop" : {
      "x" : 1971,
      "y" : 1776,
      "width" : 111,
      "height" : 51
    },
    "textPosition" : {
      "x" : 1981,
      "y" : 1777
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2082,
          "y" : 1776
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2082,
          "y" : 1776
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 28929,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2085,
          "y" : 1811
        },
        "to" : {
          "x" : 2188,
          "y" : 1832
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 28924,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2001,
          "y" : 1773
        },
        "to" : {
          "x" : 1934,
          "y" : 1704
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1993,
          "y" : 1771
        },
        "b" : {
          "x" : 2001,
          "y" : 1773
        },
        "c" : {
          "x" : 1999,
          "y" : 1765
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1999,
          "y" : 1765
        }
      }
    }, {
      "edgeId" : 28927,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1968,
          "y" : 1822
        },
        "to" : {
          "x" : 1846,
          "y" : 1872
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1963,
          "y" : 1828
        },
        "b" : {
          "x" : 1968,
          "y" : 1822
        },
        "c" : {
          "x" : 1960,
          "y" : 1821
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1960,
          "y" : 1821
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 28929,
    "reactomeId" : 10004460,
    "displayName" : "Translocation of PLC-gamma1 to PIP2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2237,
      "y" : 1833
    },
    "minX" : 2188,
    "maxX" : 2269,
    "minY" : 1820,
    "maxY" : 1839,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2188,
        "y" : 1832
      },
      "to" : {
        "x" : 2237,
        "y" : 1833
      }
    }, {
      "from" : {
        "x" : 2237,
        "y" : 1833
      },
      "to" : {
        "x" : 2269,
        "y" : 1820
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2264,
        "y" : 1826
      },
      "b" : {
        "x" : 2269,
        "y" : 1820
      },
      "c" : {
        "x" : 2261,
        "y" : 1819
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2261,
        "y" : 1819
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2237,
        "y" : 1833
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2237,
        "y" : 1833
      }
    },
    "inputs" : [ {
      "id" : 28930,
      "points" : [ {
        "x" : 2175,
        "y" : 1812
      } ]
    }, {
      "id" : 28926,
      "points" : [ {
        "x" : 2085,
        "y" : 1811
      } ]
    } ],
    "outputs" : [ {
      "id" : 28931
    } ]
  }, {
    "id" : 28932,
    "reactomeId" : 10004482,
    "displayName" : "PLC-gamma1 hydrolyses PIP2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2379,
      "y" : 1726
    },
    "minX" : 2216,
    "maxX" : 2430,
    "minY" : 1720,
    "maxY" : 1732,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2216,
        "y" : 1725
      },
      "to" : {
        "x" : 2379,
        "y" : 1726
      }
    }, {
      "from" : {
        "x" : 2379,
        "y" : 1726
      },
      "to" : {
        "x" : 2430,
        "y" : 1726
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2373,
        "y" : 1720
      },
      "b" : {
        "x" : 2385,
        "y" : 1732
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2379,
        "y" : 1726
      }
    },
    "inputs" : [ {
      "id" : 28930,
      "points" : [ {
        "x" : 2178,
        "y" : 1776
      } ]
    }, {
      "id" : 28933,
      "points" : [ {
        "x" : 2210,
        "y" : 1718
      } ]
    } ],
    "outputs" : [ {
      "id" : 28934,
      "points" : [ {
        "x" : 2499,
        "y" : 1774
      } ]
    }, {
      "id" : 28935,
      "points" : [ {
        "x" : 2482,
        "y" : 1684
      } ]
    } ],
    "catalysts" : [ {
      "id" : 28936,
      "points" : [ {
        "x" : 2439,
        "y" : 1781
      } ]
    } ]
  }, {
    "id" : 28937,
    "reactomeId" : 10004319,
    "displayName" : "Recruitment of PI3K to plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3236,
      "y" : 1674
    },
    "minX" : 3230,
    "maxX" : 3242,
    "minY" : 1646,
    "maxY" : 1697,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3237,
        "y" : 1697
      },
      "to" : {
        "x" : 3236,
        "y" : 1674
      }
    }, {
      "from" : {
        "x" : 3236,
        "y" : 1674
      },
      "to" : {
        "x" : 3236,
        "y" : 1646
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3240,
        "y" : 1653
      },
      "b" : {
        "x" : 3236,
        "y" : 1646
      },
      "c" : {
        "x" : 3232,
        "y" : 1653
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3232,
        "y" : 1653
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3236,
        "y" : 1674
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3236,
        "y" : 1674
      }
    },
    "inputs" : [ {
      "id" : 28938,
      "points" : [ {
        "x" : 3237,
        "y" : 1720
      } ]
    }, {
      "id" : 28939,
      "points" : [ {
        "x" : 3153,
        "y" : 1711
      } ]
    } ],
    "outputs" : [ {
      "id" : 28940
    } ]
  }, {
    "id" : 28941,
    "reactomeId" : 10004463,
    "displayName" : "PI3K bound to TRAT1 phosphorylates PIP2 to PIP3",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3202,
      "y" : 1515
    },
    "minX" : 3196,
    "maxX" : 3208,
    "minY" : 1492,
    "maxY" : 1542,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3201,
        "y" : 1542
      },
      "to" : {
        "x" : 3202,
        "y" : 1515
      }
    }, {
      "from" : {
        "x" : 3202,
        "y" : 1515
      },
      "to" : {
        "x" : 3202,
        "y" : 1492
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3196,
        "y" : 1509
      },
      "b" : {
        "x" : 3208,
        "y" : 1521
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3202,
        "y" : 1515
      }
    },
    "inputs" : [ {
      "id" : 28942,
      "points" : [ {
        "x" : 3187,
        "y" : 1554
      } ]
    }, {
      "id" : 28943,
      "points" : [ {
        "x" : 3216,
        "y" : 1553
      } ]
    } ],
    "outputs" : [ {
      "id" : 28944,
      "points" : [ {
        "x" : 3227,
        "y" : 1461
      } ]
    }, {
      "id" : 28945,
      "points" : [ {
        "x" : 3188,
        "y" : 1484
      } ]
    } ],
    "catalysts" : [ {
      "id" : 28940,
      "points" : [ {
        "x" : 3247,
        "y" : 1618
      }, {
        "x" : 3278,
        "y" : 1593
      }, {
        "x" : 3277,
        "y" : 1513
      } ]
    } ]
  }, {
    "id" : 28946,
    "reactomeId" : 10004403,
    "displayName" : "Hydrolysis of PIP3 to PI(3,4)P2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3238,
      "y" : 1357
    },
    "minX" : 3232,
    "maxX" : 3244,
    "minY" : 1321,
    "maxY" : 1396,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3238,
        "y" : 1396
      },
      "to" : {
        "x" : 3238,
        "y" : 1357
      }
    }, {
      "from" : {
        "x" : 3238,
        "y" : 1357
      },
      "to" : {
        "x" : 3238,
        "y" : 1321
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3232,
        "y" : 1351
      },
      "b" : {
        "x" : 3244,
        "y" : 1363
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3238,
        "y" : 1357
      }
    },
    "inputs" : [ {
      "id" : 28947,
      "points" : [ {
        "x" : 3211,
        "y" : 1405
      } ]
    }, {
      "id" : 28944,
      "points" : [ {
        "x" : 3238,
        "y" : 1425
      } ]
    } ],
    "outputs" : [ {
      "id" : 28948,
      "points" : [ {
        "x" : 3238,
        "y" : 1274
      } ]
    }, {
      "id" : 28949,
      "points" : [ {
        "x" : 3192,
        "y" : 1277
      } ]
    } ],
    "catalysts" : [ {
      "id" : 28950,
      "points" : [ {
        "x" : 3199,
        "y" : 1357
      } ]
    } ]
  }, {
    "id" : 28951,
    "reactomeId" : 10004209,
    "displayName" : "Translocation of PDK1 to Plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3206,
      "y" : 1064
    },
    "minX" : 3200,
    "maxX" : 3236,
    "minY" : 948,
    "maxY" : 1086,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3206,
        "y" : 1086
      },
      "to" : {
        "x" : 3206,
        "y" : 1064
      }
    }, {
      "from" : {
        "x" : 3206,
        "y" : 1064
      },
      "to" : {
        "x" : 3236,
        "y" : 948
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3238,
        "y" : 956
      },
      "b" : {
        "x" : 3236,
        "y" : 948
      },
      "c" : {
        "x" : 3230,
        "y" : 954
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3230,
        "y" : 954
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3206,
        "y" : 1064
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3206,
        "y" : 1064
      }
    },
    "inputs" : [ {
      "id" : 28952,
      "points" : [ {
        "x" : 3227,
        "y" : 1102
      } ]
    }, {
      "id" : 28953,
      "points" : [ {
        "x" : 3158,
        "y" : 1105
      } ]
    } ],
    "outputs" : [ {
      "id" : 28954
    } ]
  }, {
    "id" : 28955,
    "reactomeId" : 10004450,
    "displayName" : "Translocation of PKC theta to plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3218,
      "y" : 819
    },
    "minX" : 3212,
    "maxX" : 3224,
    "minY" : 787,
    "maxY" : 846,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3218,
        "y" : 846
      },
      "to" : {
        "x" : 3218,
        "y" : 819
      }
    }, {
      "from" : {
        "x" : 3218,
        "y" : 819
      },
      "to" : {
        "x" : 3224,
        "y" : 787
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3227,
        "y" : 795
      },
      "b" : {
        "x" : 3224,
        "y" : 787
      },
      "c" : {
        "x" : 3219,
        "y" : 793
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3219,
        "y" : 793
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3218,
        "y" : 819
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3218,
        "y" : 819
      }
    },
    "inputs" : [ {
      "id" : 28956,
      "points" : [ {
        "x" : 3173,
        "y" : 860
      } ]
    }, {
      "id" : 28957,
      "points" : [ {
        "x" : 3230,
        "y" : 864
      } ]
    } ],
    "outputs" : [ {
      "id" : 28958
    } ]
  }, {
    "id" : 28959,
    "reactomeId" : 10004446,
    "displayName" : "Change of PKC theta conformation",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3121,
      "y" : 687
    },
    "minX" : 3115,
    "maxX" : 3127,
    "minY" : 649,
    "maxY" : 738,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3121,
        "y" : 738
      },
      "to" : {
        "x" : 3121,
        "y" : 687
      }
    }, {
      "from" : {
        "x" : 3121,
        "y" : 687
      },
      "to" : {
        "x" : 3121,
        "y" : 649
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3115,
        "y" : 681
      },
      "b" : {
        "x" : 3127,
        "y" : 693
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3121,
        "y" : 687
      }
    },
    "inputs" : [ {
      "id" : 28958,
      "points" : [ {
        "x" : 3167,
        "y" : 750
      } ]
    }, {
      "id" : 28960,
      "points" : [ {
        "x" : 3107,
        "y" : 752
      } ]
    } ],
    "outputs" : [ {
      "id" : 28961,
      "points" : [ {
        "x" : 3188,
        "y" : 626
      } ]
    }, {
      "id" : 28962,
      "points" : [ {
        "x" : 3099,
        "y" : 632
      } ]
    } ],
    "catalysts" : [ {
      "id" : 28963,
      "points" : [ {
        "x" : 3176,
        "y" : 686
      } ]
    } ]
  }, {
    "id" : 28964,
    "reactomeId" : 10004389,
    "displayName" : "Phosphorylation of PKC theta",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3212,
      "y" : 532
    },
    "minX" : 3206,
    "maxX" : 3218,
    "minY" : 504,
    "maxY" : 556,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3212,
        "y" : 556
      },
      "to" : {
        "x" : 3212,
        "y" : 532
      }
    }, {
      "from" : {
        "x" : 3212,
        "y" : 532
      },
      "to" : {
        "x" : 3212,
        "y" : 504
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3206,
        "y" : 526
      },
      "b" : {
        "x" : 3218,
        "y" : 538
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3212,
        "y" : 532
      }
    },
    "inputs" : [ {
      "id" : 28961,
      "points" : [ {
        "x" : 3227,
        "y" : 584
      } ]
    }, {
      "id" : 28965,
      "points" : [ {
        "x" : 3162,
        "y" : 574
      } ],
      "stoichiometry" : 3
    } ],
    "outputs" : [ {
      "id" : 28966,
      "points" : [ {
        "x" : 3226,
        "y" : 483
      } ]
    }, {
      "id" : 28967,
      "points" : [ {
        "x" : 3162,
        "y" : 480
      } ],
      "stoichiometry" : 3
    } ],
    "catalysts" : [ {
      "id" : 28954,
      "points" : [ {
        "x" : 3255,
        "y" : 920
      }, {
        "x" : 3317,
        "y" : 883
      }, {
        "x" : 3314,
        "y" : 529
      } ]
    } ]
  }, {
    "id" : 28968,
    "reactomeId" : 10004472,
    "displayName" : "Translocation of CARMA1 to Plasma membrane",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3025,
      "y" : 462
    },
    "minX" : 3019,
    "maxX" : 3175,
    "minY" : 415,
    "maxY" : 905,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3023,
        "y" : 905
      },
      "to" : {
        "x" : 3025,
        "y" : 462
      }
    }, {
      "from" : {
        "x" : 3025,
        "y" : 462
      },
      "to" : {
        "x" : 3175,
        "y" : 415
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3170,
        "y" : 421
      },
      "b" : {
        "x" : 3175,
        "y" : 415
      },
      "c" : {
        "x" : 3167,
        "y" : 413
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3167,
        "y" : 413
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3025,
        "y" : 462
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3025,
        "y" : 462
      }
    },
    "inputs" : [ {
      "id" : 28954,
      "points" : [ {
        "x" : 3185,
        "y" : 927
      } ]
    }, {
      "id" : 28969,
      "points" : [ {
        "x" : 3003,
        "y" : 932
      } ]
    } ],
    "outputs" : [ {
      "id" : 28970
    } ]
  }, {
    "id" : 28971,
    "reactomeId" : 10004490,
    "displayName" : "Phosphorylation of CARMA1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3236,
      "y" : 329
    },
    "minX" : 3230,
    "maxX" : 3242,
    "minY" : 307,
    "maxY" : 353,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3236,
        "y" : 353
      },
      "to" : {
        "x" : 3236,
        "y" : 329
      }
    }, {
      "from" : {
        "x" : 3236,
        "y" : 329
      },
      "to" : {
        "x" : 3236,
        "y" : 307
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3230,
        "y" : 323
      },
      "b" : {
        "x" : 3242,
        "y" : 335
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3236,
        "y" : 329
      }
    },
    "inputs" : [ {
      "id" : 28970,
      "points" : [ {
        "x" : 3236,
        "y" : 377
      } ]
    }, {
      "id" : 28972,
      "points" : [ {
        "x" : 3179,
        "y" : 362
      } ]
    } ],
    "outputs" : [ {
      "id" : 28973,
      "points" : [ {
        "x" : 3183,
        "y" : 288
      } ]
    }, {
      "id" : 28974,
      "points" : [ {
        "x" : 3236,
        "y" : 263
      } ]
    } ],
    "catalysts" : [ {
      "id" : 28966,
      "points" : [ {
        "x" : 3299,
        "y" : 462
      }, {
        "x" : 3318,
        "y" : 462
      }, {
        "x" : 3318,
        "y" : 328
      } ]
    } ]
  }, {
    "id" : 28975,
    "reactomeId" : 10004494,
    "displayName" : "Oligomerization of CARMA1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3208,
      "y" : 173
    },
    "minX" : 3201,
    "maxX" : 3233,
    "minY" : 91,
    "maxY" : 201,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3201,
        "y" : 201
      },
      "to" : {
        "x" : 3208,
        "y" : 173
      }
    }, {
      "from" : {
        "x" : 3208,
        "y" : 173
      },
      "to" : {
        "x" : 3233,
        "y" : 91
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3235,
        "y" : 99
      },
      "b" : {
        "x" : 3233,
        "y" : 91
      },
      "c" : {
        "x" : 3227,
        "y" : 96
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3227,
        "y" : 96
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3208,
        "y" : 173
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3208,
        "y" : 173
      }
    },
    "inputs" : [ {
      "id" : 28976,
      "points" : [ {
        "x" : 3170,
        "y" : 210
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 28974,
      "points" : [ {
        "x" : 3228,
        "y" : 235
      } ]
    } ],
    "outputs" : [ {
      "id" : 28977
    } ]
  }, {
    "id" : 28978,
    "reactomeId" : 10004526,
    "displayName" : "Interaction of Bcl10 to CARMA1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3154,
      "y" : 74
    },
    "minX" : 3120,
    "maxX" : 3170,
    "minY" : 68,
    "maxY" : 80,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 3170,
        "y" : 74
      },
      "to" : {
        "x" : 3154,
        "y" : 74
      }
    }, {
      "from" : {
        "x" : 3154,
        "y" : 74
      },
      "to" : {
        "x" : 3120,
        "y" : 74
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3127,
        "y" : 70
      },
      "b" : {
        "x" : 3120,
        "y" : 74
      },
      "c" : {
        "x" : 3127,
        "y" : 78
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 3127,
        "y" : 78
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 3154,
        "y" : 74
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 3154,
        "y" : 74
      }
    },
    "inputs" : [ {
      "id" : 28977,
      "points" : [ {
        "x" : 3184,
        "y" : 74
      } ]
    }, {
      "id" : 28979,
      "points" : [ {
        "x" : 3170,
        "y" : 101
      } ]
    } ],
    "outputs" : [ {
      "id" : 28980
    } ]
  }, {
    "id" : 28981,
    "reactomeId" : 10004524,
    "displayName" : "Phosphorylation of Bcl10",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2970,
      "y" : 75
    },
    "minX" : 2952,
    "maxX" : 2995,
    "minY" : 69,
    "maxY" : 81,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2995,
        "y" : 75
      },
      "to" : {
        "x" : 2970,
        "y" : 75
      }
    }, {
      "from" : {
        "x" : 2970,
        "y" : 75
      },
      "to" : {
        "x" : 2952,
        "y" : 75
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2964,
        "y" : 69
      },
      "b" : {
        "x" : 2976,
        "y" : 81
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2970,
        "y" : 75
      }
    },
    "inputs" : [ {
      "id" : 28980,
      "points" : [ {
        "x" : 3013,
        "y" : 75
      } ]
    }, {
      "id" : 28982,
      "points" : [ {
        "x" : 3032,
        "y" : 119
      } ]
    } ],
    "outputs" : [ {
      "id" : 28983,
      "points" : [ {
        "x" : 2909,
        "y" : 119
      } ]
    }, {
      "id" : 28984,
      "points" : [ {
        "x" : 2908,
        "y" : 75
      } ]
    } ],
    "catalysts" : [ {
      "id" : 28985,
      "points" : [ {
        "x" : 2970,
        "y" : 125
      } ]
    } ]
  }, {
    "id" : 28986,
    "reactomeId" : 10004532,
    "displayName" : "Oligomerization of Bcl10",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2745,
      "y" : 73
    },
    "minX" : 2719,
    "maxX" : 2767,
    "minY" : 67,
    "maxY" : 79,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2767,
        "y" : 73
      },
      "to" : {
        "x" : 2745,
        "y" : 73
      }
    }, {
      "from" : {
        "x" : 2745,
        "y" : 73
      },
      "to" : {
        "x" : 2719,
        "y" : 73
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2726,
        "y" : 69
      },
      "b" : {
        "x" : 2719,
        "y" : 73
      },
      "c" : {
        "x" : 2726,
        "y" : 77
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2726,
        "y" : 77
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2745,
        "y" : 73
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2745,
        "y" : 73
      }
    },
    "inputs" : [ {
      "id" : 28987,
      "points" : [ {
        "x" : 2785,
        "y" : 123
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 28984,
      "points" : [ {
        "x" : 2784,
        "y" : 73
      } ]
    } ],
    "outputs" : [ {
      "id" : 28988
    } ]
  }, {
    "id" : 28989,
    "reactomeId" : 10004530,
    "displayName" : "Interaction and oligomerization of MALT1 to Bcl10",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2534,
      "y" : 73
    },
    "minX" : 2496,
    "maxX" : 2563,
    "minY" : 67,
    "maxY" : 79,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2563,
        "y" : 73
      },
      "to" : {
        "x" : 2534,
        "y" : 73
      }
    }, {
      "from" : {
        "x" : 2534,
        "y" : 73
      },
      "to" : {
        "x" : 2496,
        "y" : 73
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2503,
        "y" : 69
      },
      "b" : {
        "x" : 2496,
        "y" : 73
      },
      "c" : {
        "x" : 2503,
        "y" : 77
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2503,
        "y" : 77
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2534,
        "y" : 73
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2534,
        "y" : 73
      }
    },
    "inputs" : [ {
      "id" : 28988,
      "points" : [ {
        "x" : 2581,
        "y" : 73
      } ]
    }, {
      "id" : 28990,
      "points" : [ {
        "x" : 2607,
        "y" : 115
      } ]
    } ],
    "outputs" : [ {
      "id" : 28991
    } ]
  }, {
    "id" : 28862,
    "reactomeId" : 10004913,
    "displayName" : "Interaction of Csk with PAG",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 255,
      "y" : 74
    },
    "minX" : 233,
    "maxX" : 322,
    "minY" : 68,
    "maxY" : 80,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 233,
        "y" : 74
      },
      "to" : {
        "x" : 255,
        "y" : 74
      }
    }, {
      "from" : {
        "x" : 255,
        "y" : 74
      },
      "to" : {
        "x" : 322,
        "y" : 74
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 315,
        "y" : 78
      },
      "b" : {
        "x" : 322,
        "y" : 74
      },
      "c" : {
        "x" : 315,
        "y" : 70
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 315,
        "y" : 70
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 255,
        "y" : 74
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 255,
        "y" : 74
      }
    },
    "inputs" : [ {
      "id" : 28863,
      "points" : [ {
        "x" : 191,
        "y" : 74
      } ]
    }, {
      "id" : 28864,
      "points" : [ {
        "x" : 166,
        "y" : 120
      } ]
    } ],
    "outputs" : [ {
      "id" : 28865
    } ]
  }, {
    "id" : 28992,
    "reactomeId" : 10004528,
    "displayName" : "Translocation of TRAF6 to CBM complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2307,
      "y" : 74
    },
    "minX" : 2278,
    "maxX" : 2332,
    "minY" : 68,
    "maxY" : 80,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2332,
        "y" : 74
      },
      "to" : {
        "x" : 2307,
        "y" : 74
      }
    }, {
      "from" : {
        "x" : 2307,
        "y" : 74
      },
      "to" : {
        "x" : 2278,
        "y" : 74
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2285,
        "y" : 70
      },
      "b" : {
        "x" : 2278,
        "y" : 74
      },
      "c" : {
        "x" : 2285,
        "y" : 78
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2285,
        "y" : 78
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2307,
        "y" : 74
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2307,
        "y" : 74
      }
    },
    "inputs" : [ {
      "id" : 28991,
      "points" : [ {
        "x" : 2357,
        "y" : 74
      } ]
    }, {
      "id" : 28993,
      "points" : [ {
        "x" : 2361,
        "y" : 120
      } ],
      "stoichiometry" : 3
    } ],
    "outputs" : [ {
      "id" : 28994
    } ]
  }, {
    "id" : 28866,
    "reactomeId" : 10004396,
    "displayName" : "Inactivation of Lck by Csk",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 680,
      "y" : 71
    },
    "minX" : 645,
    "maxX" : 713,
    "minY" : 65,
    "maxY" : 77,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 645,
        "y" : 71
      },
      "to" : {
        "x" : 680,
        "y" : 71
      }
    }, {
      "from" : {
        "x" : 680,
        "y" : 71
      },
      "to" : {
        "x" : 713,
        "y" : 71
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 674,
        "y" : 65
      },
      "b" : {
        "x" : 686,
        "y" : 77
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 680,
        "y" : 71
      }
    },
    "inputs" : [ {
      "id" : 28867,
      "points" : [ {
        "x" : 579,
        "y" : 71
      } ]
    }, {
      "id" : 28868,
      "points" : [ {
        "x" : 614,
        "y" : 111
      } ]
    } ],
    "outputs" : [ {
      "id" : 28869,
      "points" : [ {
        "x" : 747,
        "y" : 115
      } ]
    }, {
      "id" : 28870,
      "points" : [ {
        "x" : 754,
        "y" : 71
      } ]
    } ],
    "catalysts" : [ {
      "id" : 28865,
      "points" : [ {
        "x" : 372,
        "y" : 60
      }, {
        "x" : 424,
        "y" : 13
      }, {
        "x" : 680,
        "y" : 13
      } ]
    } ],
    "inhibitors" : [ {
      "id" : 28871,
      "points" : [ {
        "x" : 943,
        "y" : 56
      }, {
        "x" : 832,
        "y" : 0
      } ]
    } ]
  }, {
    "id" : 28995,
    "reactomeId" : 10004517,
    "displayName" : "Auto-ubiquitination of TRAF6",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2078,
      "y" : 74
    },
    "minX" : 2052,
    "maxX" : 2117,
    "minY" : 68,
    "maxY" : 80,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2117,
        "y" : 74
      },
      "to" : {
        "x" : 2078,
        "y" : 74
      }
    }, {
      "from" : {
        "x" : 2078,
        "y" : 74
      },
      "to" : {
        "x" : 2052,
        "y" : 74
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2072,
        "y" : 68
      },
      "b" : {
        "x" : 2084,
        "y" : 80
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2078,
        "y" : 74
      }
    },
    "inputs" : [ {
      "id" : 28994,
      "points" : [ {
        "x" : 2141,
        "y" : 74
      } ]
    }, {
      "id" : 28996,
      "points" : [ {
        "x" : 2059,
        "y" : 151
      } ],
      "stoichiometry" : 3
    }, {
      "id" : 28997,
      "points" : [ {
        "x" : 2179,
        "y" : 151
      } ],
      "stoichiometry" : 3
    } ],
    "outputs" : [ {
      "id" : 28998,
      "points" : [ {
        "x" : 2016,
        "y" : 74
      } ]
    }, {
      "id" : 28996,
      "points" : [ {
        "x" : 2052,
        "y" : 151
      } ],
      "stoichiometry" : 3
    } ],
    "catalysts" : [ {
      "id" : 28994,
      "points" : [ {
        "x" : 2141,
        "y" : 59
      }, {
        "x" : 2078,
        "y" : 42
      } ]
    } ]
  }, {
    "id" : 28999,
    "reactomeId" : 10004558,
    "displayName" : "Activation of TAK1-TAB2 complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1827,
      "y" : 72
    },
    "minX" : 1792,
    "maxX" : 1854,
    "minY" : 66,
    "maxY" : 78,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1854,
        "y" : 72
      },
      "to" : {
        "x" : 1827,
        "y" : 72
      }
    }, {
      "from" : {
        "x" : 1827,
        "y" : 72
      },
      "to" : {
        "x" : 1792,
        "y" : 72
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1821,
        "y" : 66
      },
      "b" : {
        "x" : 1833,
        "y" : 78
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1827,
        "y" : 72
      }
    },
    "inputs" : [ {
      "id" : 28998,
      "points" : [ {
        "x" : 1897,
        "y" : 72
      } ]
    }, {
      "id" : 29000,
      "points" : [ {
        "x" : 1874,
        "y" : 168
      } ]
    }, {
      "id" : 29001,
      "points" : [ {
        "x" : 1893,
        "y" : 118
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 29002,
      "points" : [ {
        "x" : 1756,
        "y" : 72
      } ]
    }, {
      "id" : 29003,
      "points" : [ {
        "x" : 1760,
        "y" : 122
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 29000,
      "points" : [ {
        "x" : 1857,
        "y" : 168
      }, {
        "x" : 1827,
        "y" : 154
      } ]
    } ]
  }, {
    "id" : 28872,
    "reactomeId" : 10004356,
    "displayName" : "Dephosphorylation of Lck-pY505 by CD45",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 696,
      "y" : 240
    },
    "minX" : 556,
    "maxX" : 808,
    "minY" : 217,
    "maxY" : 246,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 808,
        "y" : 217
      },
      "to" : {
        "x" : 696,
        "y" : 240
      }
    }, {
      "from" : {
        "x" : 696,
        "y" : 240
      },
      "to" : {
        "x" : 556,
        "y" : 219
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 690,
        "y" : 234
      },
      "b" : {
        "x" : 702,
        "y" : 246
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 696,
        "y" : 240
      }
    },
    "inputs" : [ {
      "id" : 28873,
      "points" : [ {
        "x" : 772,
        "y" : 192
      } ]
    }, {
      "id" : 28870,
      "points" : [ {
        "x" : 824,
        "y" : 107
      } ]
    } ],
    "outputs" : [ {
      "id" : 28874,
      "points" : [ {
        "x" : 595,
        "y" : 182
      } ]
    }, {
      "id" : 28867,
      "points" : [ {
        "x" : 521,
        "y" : 99
      } ]
    } ],
    "catalysts" : [ {
      "id" : 28871,
      "points" : [ {
        "x" : 958,
        "y" : 90
      }, {
        "x" : 872,
        "y" : 286
      }, {
        "x" : 696,
        "y" : 286
      } ]
    } ]
  }, {
    "id" : 28875,
    "reactomeId" : 10004440,
    "displayName" : "Activation of Lck",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 393,
      "y" : 250
    },
    "minX" : 361,
    "maxX" : 456,
    "minY" : 182,
    "maxY" : 256,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 456,
        "y" : 182
      },
      "to" : {
        "x" : 432,
        "y" : 250
      }
    }, {
      "from" : {
        "x" : 432,
        "y" : 250
      },
      "to" : {
        "x" : 393,
        "y" : 250
      }
    }, {
      "from" : {
        "x" : 393,
        "y" : 250
      },
      "to" : {
        "x" : 361,
        "y" : 250
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 387,
        "y" : 244
      },
      "b" : {
        "x" : 399,
        "y" : 256
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 393,
        "y" : 250
      }
    },
    "inputs" : [ {
      "id" : 28867,
      "points" : [ {
        "x" : 500,
        "y" : 99
      } ]
    }, {
      "id" : 28876,
      "points" : [ {
        "x" : 472,
        "y" : 192
      } ]
    } ],
    "outputs" : [ {
      "id" : 28877,
      "points" : [ {
        "x" : 143,
        "y" : 250
      } ]
    }, {
      "id" : 28878,
      "points" : [ {
        "x" : 341,
        "y" : 212
      } ]
    } ],
    "catalysts" : [ {
      "id" : 28867,
      "points" : [ {
        "x" : 449,
        "y" : 91
      }, {
        "x" : 393,
        "y" : 111
      } ]
    } ]
  }, {
    "id" : 29004,
    "reactomeId" : 10004550,
    "displayName" : "Activation of IKK complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1594,
      "y" : 186
    },
    "minX" : 1561,
    "maxX" : 1624,
    "minY" : 180,
    "maxY" : 192,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1624,
        "y" : 186
      },
      "to" : {
        "x" : 1594,
        "y" : 186
      }
    }, {
      "from" : {
        "x" : 1594,
        "y" : 186
      },
      "to" : {
        "x" : 1561,
        "y" : 186
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1588,
        "y" : 180
      },
      "b" : {
        "x" : 1600,
        "y" : 192
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1594,
        "y" : 186
      }
    },
    "inputs" : [ {
      "id" : 29005,
      "points" : [ {
        "x" : 1669,
        "y" : 226
      } ]
    }, {
      "id" : 29006,
      "points" : [ {
        "x" : 1656,
        "y" : 162
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 29007,
      "points" : [ {
        "x" : 1509,
        "y" : 227
      } ]
    }, {
      "id" : 29008,
      "points" : [ {
        "x" : 1517,
        "y" : 158
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 29002,
      "points" : [ {
        "x" : 1615,
        "y" : 73
      }, {
        "x" : 1594,
        "y" : 73
      } ]
    } ]
  }, {
    "id" : 28879,
    "reactomeId" : 10004286,
    "displayName" : "Phosphorylation of ITAM motifs in CD3 complexes",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 127,
      "y" : 365
    },
    "minX" : 121,
    "maxX" : 133,
    "minY" : 333,
    "maxY" : 400,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 127,
        "y" : 333
      },
      "to" : {
        "x" : 127,
        "y" : 365
      }
    }, {
      "from" : {
        "x" : 127,
        "y" : 365
      },
      "to" : {
        "x" : 127,
        "y" : 400
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 121,
        "y" : 359
      },
      "b" : {
        "x" : 133,
        "y" : 371
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 127,
        "y" : 365
      }
    },
    "inputs" : [ {
      "id" : 28877,
      "points" : [ {
        "x" : 102,
        "y" : 293
      } ]
    }, {
      "id" : 28880,
      "points" : [ {
        "x" : 158,
        "y" : 310
      } ],
      "stoichiometry" : 20
    } ],
    "outputs" : [ {
      "id" : 28881,
      "points" : [ {
        "x" : 105,
        "y" : 435
      } ]
    }, {
      "id" : 28882,
      "points" : [ {
        "x" : 170,
        "y" : 435
      } ],
      "stoichiometry" : 20
    } ],
    "catalysts" : [ {
      "id" : 28877,
      "points" : [ {
        "x" : 86,
        "y" : 293
      }, {
        "x" : 98,
        "y" : 364
      } ]
    } ]
  }, {
    "id" : 29009,
    "reactomeId" : 10004569,
    "displayName" : "Ubiquitination of NEMO by TRAF6",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1684,
      "y" : 331
    },
    "minX" : 1647,
    "maxX" : 1757,
    "minY" : 325,
    "maxY" : 337,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1647,
        "y" : 331
      },
      "to" : {
        "x" : 1684,
        "y" : 331
      }
    }, {
      "from" : {
        "x" : 1684,
        "y" : 331
      },
      "to" : {
        "x" : 1757,
        "y" : 331
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1678,
        "y" : 325
      },
      "b" : {
        "x" : 1690,
        "y" : 337
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1684,
        "y" : 331
      }
    },
    "inputs" : [ {
      "id" : 29007,
      "points" : [ {
        "x" : 1523,
        "y" : 269
      } ]
    }, {
      "id" : 29010,
      "points" : [ {
        "x" : 1603,
        "y" : 379
      } ]
    }, {
      "id" : 29011,
      "points" : [ {
        "x" : 1600,
        "y" : 331
      } ]
    } ],
    "outputs" : [ {
      "id" : 29012,
      "points" : [ {
        "x" : 1831,
        "y" : 383
      } ]
    }, {
      "id" : 29010,
      "points" : [ {
        "x" : 1622,
        "y" : 379
      } ]
    } ],
    "catalysts" : [ {
      "id" : 28998,
      "points" : [ {
        "x" : 1956,
        "y" : 102
      }, {
        "x" : 1959,
        "y" : 299
      }, {
        "x" : 1684,
        "y" : 303
      } ]
    } ]
  }, {
    "id" : 28883,
    "reactomeId" : 10004454,
    "displayName" : "Recruitment of ZAP-70 to phosphorylated ITAMs",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 100,
      "y" : 576
    },
    "minX" : 92,
    "maxX" : 106,
    "minY" : 534,
    "maxY" : 619,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 100,
        "y" : 534
      },
      "to" : {
        "x" : 100,
        "y" : 576
      }
    }, {
      "from" : {
        "x" : 100,
        "y" : 576
      },
      "to" : {
        "x" : 92,
        "y" : 619
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 89,
        "y" : 611
      },
      "b" : {
        "x" : 92,
        "y" : 619
      },
      "c" : {
        "x" : 97,
        "y" : 613
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 97,
        "y" : 613
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 100,
        "y" : 576
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 100,
        "y" : 576
      }
    },
    "inputs" : [ {
      "id" : 28881,
      "points" : [ {
        "x" : 94,
        "y" : 519
      } ]
    }, {
      "id" : 28884,
      "points" : [ {
        "x" : 137,
        "y" : 538
      } ]
    } ],
    "outputs" : [ {
      "id" : 28885
    } ]
  }, {
    "id" : 29013,
    "reactomeId" : 10004574,
    "displayName" : "p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1857,
      "y" : 597
    },
    "minX" : 1828,
    "maxX" : 1898,
    "minY" : 591,
    "maxY" : 603,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1898,
        "y" : 597
      },
      "to" : {
        "x" : 1857,
        "y" : 597
      }
    }, {
      "from" : {
        "x" : 1857,
        "y" : 597
      },
      "to" : {
        "x" : 1828,
        "y" : 597
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1851,
        "y" : 591
      },
      "b" : {
        "x" : 1863,
        "y" : 603
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1857,
        "y" : 597
      }
    },
    "inputs" : [ {
      "id" : 29014,
      "points" : [ {
        "x" : 1924,
        "y" : 577
      } ]
    }, {
      "id" : 29015,
      "points" : [ {
        "x" : 1928,
        "y" : 612
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 29016,
      "points" : [ {
        "x" : 1791,
        "y" : 615
      } ]
    }, {
      "id" : 29017,
      "points" : [ {
        "x" : 1788,
        "y" : 573
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 29012,
      "points" : [ {
        "x" : 1856,
        "y" : 425
      } ]
    } ]
  }, {
    "id" : 28886,
    "reactomeId" : 10004300,
    "displayName" : "Phosphorylation of ZAP-70 by Lck",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 131,
      "y" : 751
    },
    "minX" : 125,
    "maxX" : 137,
    "minY" : 712,
    "maxY" : 784,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 132,
        "y" : 712
      },
      "to" : {
        "x" : 131,
        "y" : 751
      }
    }, {
      "from" : {
        "x" : 131,
        "y" : 751
      },
      "to" : {
        "x" : 132,
        "y" : 784
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 125,
        "y" : 745
      },
      "b" : {
        "x" : 137,
        "y" : 757
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 131,
        "y" : 751
      }
    },
    "inputs" : [ {
      "id" : 28885,
      "points" : [ {
        "x" : 105,
        "y" : 675
      } ]
    }, {
      "id" : 28887,
      "points" : [ {
        "x" : 157,
        "y" : 691
      } ]
    } ],
    "outputs" : [ {
      "id" : 28888,
      "points" : [ {
        "x" : 88,
        "y" : 890
      } ]
    }, {
      "id" : 28889,
      "points" : [ {
        "x" : 178,
        "y" : 858
      } ]
    } ],
    "catalysts" : [ {
      "id" : 28877,
      "points" : [ {
        "x" : 45,
        "y" : 293
      }, {
        "x" : 3,
        "y" : 337
      }, {
        "x" : 7,
        "y" : 752
      } ]
    } ]
  }, {
    "id" : 28890,
    "reactomeId" : 10004308,
    "displayName" : "Activation of ZAP-70",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 127,
      "y" : 1005
    },
    "minX" : 121,
    "maxX" : 133,
    "minY" : 967,
    "maxY" : 1089,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 127,
        "y" : 967
      },
      "to" : {
        "x" : 127,
        "y" : 1005
      }
    }, {
      "from" : {
        "x" : 127,
        "y" : 1005
      },
      "to" : {
        "x" : 127,
        "y" : 1089
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 121,
        "y" : 999
      },
      "b" : {
        "x" : 133,
        "y" : 1011
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 127,
        "y" : 1005
      }
    },
    "inputs" : [ {
      "id" : 28888,
      "points" : [ {
        "x" : 95,
        "y" : 932
      } ]
    }, {
      "id" : 28891,
      "points" : [ {
        "x" : 168,
        "y" : 938
      } ]
    } ],
    "outputs" : [ {
      "id" : 28892,
      "points" : [ {
        "x" : 93,
        "y" : 1177
      } ]
    }, {
      "id" : 28893,
      "points" : [ {
        "x" : 169,
        "y" : 1105
      } ]
    } ],
    "catalysts" : [ {
      "id" : 28888,
      "points" : [ {
        "x" : 83,
        "y" : 932
      }, {
        "x" : 94,
        "y" : 1004
      } ]
    } ]
  }, {
    "id" : 29018,
    "reactomeId" : 10016459,
    "displayName" : "p-SLP-76 binds ADAP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1003,
      "y" : 1089
    },
    "minX" : 997,
    "maxX" : 1009,
    "minY" : 1059,
    "maxY" : 1112,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1004,
        "y" : 1112
      },
      "to" : {
        "x" : 1003,
        "y" : 1089
      }
    }, {
      "from" : {
        "x" : 1003,
        "y" : 1089
      },
      "to" : {
        "x" : 1003,
        "y" : 1059
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1007,
        "y" : 1066
      },
      "b" : {
        "x" : 1003,
        "y" : 1059
      },
      "c" : {
        "x" : 999,
        "y" : 1066
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 999,
        "y" : 1066
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1003,
        "y" : 1089
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1003,
        "y" : 1089
      }
    },
    "inputs" : [ {
      "id" : 29019,
      "points" : [ {
        "x" : 1030,
        "y" : 1135
      } ]
    }, {
      "id" : 29020,
      "points" : [ {
        "x" : 972,
        "y" : 1141
      } ]
    } ],
    "outputs" : [ {
      "id" : 29021
    } ]
  }, {
    "id" : 28894,
    "reactomeId" : 10004410,
    "displayName" : "Phosphorylation of TBSMs in LAT",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 80,
      "y" : 1313
    },
    "minX" : 74,
    "maxX" : 86,
    "minY" : 1286,
    "maxY" : 1343,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 80,
        "y" : 1286
      },
      "to" : {
        "x" : 80,
        "y" : 1313
      }
    }, {
      "from" : {
        "x" : 80,
        "y" : 1313
      },
      "to" : {
        "x" : 80,
        "y" : 1343
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 74,
        "y" : 1307
      },
      "b" : {
        "x" : 86,
        "y" : 1319
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 80,
        "y" : 1313
      }
    },
    "inputs" : [ {
      "id" : 28895,
      "points" : [ {
        "x" : 112,
        "y" : 1272
      } ],
      "stoichiometry" : 5
    }, {
      "id" : 28896,
      "points" : [ {
        "x" : 80,
        "y" : 1255
      } ]
    } ],
    "outputs" : [ {
      "id" : 28897,
      "points" : [ {
        "x" : 80,
        "y" : 1407
      } ]
    }, {
      "id" : 28898,
      "points" : [ {
        "x" : 124,
        "y" : 1374
      } ],
      "stoichiometry" : 5
    } ],
    "catalysts" : [ {
      "id" : 28892,
      "points" : [ {
        "x" : 29,
        "y" : 1190
      }, {
        "x" : 0,
        "y" : 1190
      }, {
        "x" : 32,
        "y" : 1312
      } ]
    } ]
  }, {
    "id" : 29022,
    "reactomeId" : 10016473,
    "displayName" : "p-SLP-76 binds NCK",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1130,
      "y" : 1086
    },
    "minX" : 1124,
    "maxX" : 1136,
    "minY" : 1059,
    "maxY" : 1113,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1130,
        "y" : 1113
      },
      "to" : {
        "x" : 1130,
        "y" : 1086
      }
    }, {
      "from" : {
        "x" : 1130,
        "y" : 1086
      },
      "to" : {
        "x" : 1130,
        "y" : 1059
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1134,
        "y" : 1066
      },
      "b" : {
        "x" : 1130,
        "y" : 1059
      },
      "c" : {
        "x" : 1126,
        "y" : 1066
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1126,
        "y" : 1066
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1130,
        "y" : 1086
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1130,
        "y" : 1086
      }
    },
    "inputs" : [ {
      "id" : 29019,
      "points" : [ {
        "x" : 1090,
        "y" : 1135
      } ]
    }, {
      "id" : 29023,
      "points" : [ {
        "x" : 1158,
        "y" : 1141
      } ]
    } ],
    "outputs" : [ {
      "id" : 29024
    } ]
  }, {
    "id" : 29025,
    "reactomeId" : 10016471,
    "displayName" : "NCK binds PAK",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1169,
      "y" : 978
    },
    "minX" : 1163,
    "maxX" : 1175,
    "minY" : 946,
    "maxY" : 1008,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1168,
        "y" : 1008
      },
      "to" : {
        "x" : 1169,
        "y" : 978
      }
    }, {
      "from" : {
        "x" : 1169,
        "y" : 978
      },
      "to" : {
        "x" : 1168,
        "y" : 946
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1172,
        "y" : 953
      },
      "b" : {
        "x" : 1168,
        "y" : 946
      },
      "c" : {
        "x" : 1164,
        "y" : 953
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1164,
        "y" : 953
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1169,
        "y" : 978
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1169,
        "y" : 978
      }
    },
    "inputs" : [ {
      "id" : 29026,
      "points" : [ {
        "x" : 1204,
        "y" : 1029
      } ]
    }, {
      "id" : 29024,
      "points" : [ {
        "x" : 1141,
        "y" : 1031
      } ]
    } ],
    "outputs" : [ {
      "id" : 29027
    } ]
  }, {
    "id" : 28899,
    "reactomeId" : 10004448,
    "displayName" : "Recruitment of Gads to LAT",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 81,
      "y" : 1520
    },
    "minX" : 75,
    "maxX" : 87,
    "minY" : 1485,
    "maxY" : 1575,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 81,
        "y" : 1485
      },
      "to" : {
        "x" : 81,
        "y" : 1520
      }
    }, {
      "from" : {
        "x" : 81,
        "y" : 1520
      },
      "to" : {
        "x" : 81,
        "y" : 1575
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 77,
        "y" : 1568
      },
      "b" : {
        "x" : 81,
        "y" : 1575
      },
      "c" : {
        "x" : 85,
        "y" : 1568
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 85,
        "y" : 1568
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 81,
        "y" : 1520
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 81,
        "y" : 1520
      }
    },
    "inputs" : [ {
      "id" : 28900,
      "points" : [ {
        "x" : 126,
        "y" : 1465
      } ]
    }, {
      "id" : 28897,
      "points" : [ {
        "x" : 81,
        "y" : 1447
      } ]
    } ],
    "outputs" : [ {
      "id" : 28901
    } ]
  }, {
    "id" : 29028,
    "reactomeId" : 10055444,
    "displayName" : "beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1629,
      "y" : 642
    },
    "minX" : 1597,
    "maxX" : 1656,
    "minY" : 636,
    "maxY" : 648,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1656,
        "y" : 642
      },
      "to" : {
        "x" : 1629,
        "y" : 642
      }
    }, {
      "from" : {
        "x" : 1629,
        "y" : 642
      },
      "to" : {
        "x" : 1597,
        "y" : 642
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1623,
        "y" : 636
      },
      "b" : {
        "x" : 1635,
        "y" : 648
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1629,
        "y" : 642
      }
    },
    "inputs" : [ {
      "id" : 29029,
      "points" : [ {
        "x" : 1630,
        "y" : 702
      } ]
    }, {
      "id" : 29030,
      "points" : [ {
        "x" : 1729,
        "y" : 705
      } ],
      "stoichiometry" : 4
    }, {
      "id" : 29016,
      "points" : [ {
        "x" : 1697,
        "y" : 642
      } ]
    }, {
      "id" : 29031,
      "points" : [ {
        "x" : 1632,
        "y" : 579
      } ]
    } ],
    "outputs" : [ {
      "id" : 29029,
      "points" : [ {
        "x" : 1618,
        "y" : 702
      } ]
    }, {
      "id" : 29032,
      "points" : [ {
        "x" : 1547,
        "y" : 642
      } ]
    }, {
      "id" : 29031,
      "points" : [ {
        "x" : 1624,
        "y" : 579
      } ]
    } ],
    "catalysts" : [ {
      "id" : 29031,
      "points" : [ {
        "x" : 1629,
        "y" : 579
      } ]
    } ]
  }, {
    "id" : 28902,
    "reactomeId" : 10004405,
    "displayName" : "Recruitment of SLP-76 to Gads",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 142,
      "y" : 1698
    },
    "minX" : 136,
    "maxX" : 148,
    "minY" : 1667,
    "maxY" : 1772,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 142,
        "y" : 1667
      },
      "to" : {
        "x" : 142,
        "y" : 1698
      }
    }, {
      "from" : {
        "x" : 142,
        "y" : 1698
      },
      "to" : {
        "x" : 142,
        "y" : 1772
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 138,
        "y" : 1765
      },
      "b" : {
        "x" : 142,
        "y" : 1772
      },
      "c" : {
        "x" : 146,
        "y" : 1765
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 146,
        "y" : 1765
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 142,
        "y" : 1698
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 142,
        "y" : 1698
      }
    },
    "inputs" : [ {
      "id" : 28903,
      "points" : [ {
        "x" : 186,
        "y" : 1633
      } ]
    }, {
      "id" : 28901,
      "points" : [ {
        "x" : 90,
        "y" : 1603
      } ]
    } ],
    "outputs" : [ {
      "id" : 28904
    } ]
  }, {
    "id" : 28905,
    "reactomeId" : 10004374,
    "displayName" : "Phosphorylation of SLP-76",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 297,
      "y" : 1737
    },
    "minX" : 241,
    "maxX" : 332,
    "minY" : 1731,
    "maxY" : 1743,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 241,
        "y" : 1737
      },
      "to" : {
        "x" : 297,
        "y" : 1737
      }
    }, {
      "from" : {
        "x" : 297,
        "y" : 1737
      },
      "to" : {
        "x" : 332,
        "y" : 1737
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 291,
        "y" : 1731
      },
      "b" : {
        "x" : 303,
        "y" : 1743
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 297,
        "y" : 1737
      }
    },
    "inputs" : [ {
      "id" : 28906,
      "points" : [ {
        "x" : 207,
        "y" : 1713
      } ],
      "stoichiometry" : 3
    }, {
      "id" : 28904,
      "points" : [ {
        "x" : 174,
        "y" : 1772
      } ]
    } ],
    "outputs" : [ {
      "id" : 28907,
      "points" : [ {
        "x" : 373,
        "y" : 1765
      } ]
    }, {
      "id" : 28908,
      "points" : [ {
        "x" : 367,
        "y" : 1717
      } ],
      "stoichiometry" : 3
    } ],
    "catalysts" : [ {
      "id" : 28892,
      "points" : [ {
        "x" : 105,
        "y" : 1205
      }, {
        "x" : 296,
        "y" : 1341
      } ]
    } ]
  }, {
    "id" : 29033,
    "reactomeId" : 10055428,
    "displayName" : "26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1372,
      "y" : 643
    },
    "minX" : 1343,
    "maxX" : 1411,
    "minY" : 637,
    "maxY" : 649,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1411,
        "y" : 643
      },
      "to" : {
        "x" : 1372,
        "y" : 643
      }
    }, {
      "from" : {
        "x" : 1372,
        "y" : 643
      },
      "to" : {
        "x" : 1343,
        "y" : 643
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1350,
        "y" : 639
      },
      "b" : {
        "x" : 1343,
        "y" : 643
      },
      "c" : {
        "x" : 1350,
        "y" : 647
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1350,
        "y" : 647
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1366,
        "y" : 637
      },
      "b" : {
        "x" : 1378,
        "y" : 649
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1372,
        "y" : 643
      }
    },
    "inputs" : [ {
      "id" : 29032
    } ],
    "outputs" : [ {
      "id" : 29034
    } ],
    "catalysts" : [ {
      "id" : 29035,
      "points" : [ {
        "x" : 1372,
        "y" : 535
      } ]
    } ]
  }, {
    "id" : 29036,
    "reactomeId" : 10046365,
    "displayName" : "NFKB1:RELA translocates from the cytosol to the nucleus",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1173,
      "y" : 644
    },
    "minX" : 1134,
    "maxX" : 1210,
    "minY" : 638,
    "maxY" : 650,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1210,
        "y" : 644
      },
      "to" : {
        "x" : 1173,
        "y" : 644
      }
    }, {
      "from" : {
        "x" : 1173,
        "y" : 644
      },
      "to" : {
        "x" : 1134,
        "y" : 644
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1141,
        "y" : 640
      },
      "b" : {
        "x" : 1134,
        "y" : 644
      },
      "c" : {
        "x" : 1141,
        "y" : 648
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1141,
        "y" : 648
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1167,
        "y" : 638
      },
      "b" : {
        "x" : 1179,
        "y" : 650
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1173,
        "y" : 644
      }
    },
    "inputs" : [ {
      "id" : 29034
    } ],
    "outputs" : [ {
      "id" : 29037
    } ]
  }, {
    "id" : 28909,
    "reactomeId" : 10004465,
    "displayName" : "Recruitment of ITK to SLP-76",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 523,
      "y" : 1788
    },
    "minX" : 501,
    "maxX" : 553,
    "minY" : 1782,
    "maxY" : 1794,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 501,
        "y" : 1788
      },
      "to" : {
        "x" : 523,
        "y" : 1788
      }
    }, {
      "from" : {
        "x" : 523,
        "y" : 1788
      },
      "to" : {
        "x" : 553,
        "y" : 1791
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 546,
        "y" : 1794
      },
      "b" : {
        "x" : 553,
        "y" : 1791
      },
      "c" : {
        "x" : 547,
        "y" : 1786
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 547,
        "y" : 1786
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 523,
        "y" : 1788
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 523,
        "y" : 1788
      }
    },
    "inputs" : [ {
      "id" : 28907,
      "points" : [ {
        "x" : 471,
        "y" : 1788
      } ]
    }, {
      "id" : 28910,
      "points" : [ {
        "x" : 490,
        "y" : 1768
      } ]
    } ],
    "outputs" : [ {
      "id" : 28911
    } ]
  }, {
    "id" : 29038,
    "reactomeId" : 10076116,
    "displayName" : "Inactivation of LCK by PTPN22",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 395,
      "y" : 274
    },
    "minX" : 257,
    "maxX" : 552,
    "minY" : 236,
    "maxY" : 280,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 257,
        "y" : 263
      },
      "to" : {
        "x" : 395,
        "y" : 274
      }
    }, {
      "from" : {
        "x" : 395,
        "y" : 274
      },
      "to" : {
        "x" : 552,
        "y" : 236
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 389,
        "y" : 268
      },
      "b" : {
        "x" : 401,
        "y" : 280
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 395,
        "y" : 274
      }
    },
    "inputs" : [ {
      "id" : 28877,
      "points" : [ {
        "x" : 143,
        "y" : 255
      } ]
    }, {
      "id" : 29039,
      "points" : [ {
        "x" : 297,
        "y" : 309
      } ]
    } ],
    "outputs" : [ {
      "id" : 28867,
      "points" : [ {
        "x" : 519,
        "y" : 99
      } ]
    }, {
      "id" : 28874,
      "points" : [ {
        "x" : 595,
        "y" : 185
      } ]
    } ],
    "catalysts" : [ {
      "id" : 29040,
      "points" : [ {
        "x" : 395,
        "y" : 386
      } ]
    } ]
  }, {
    "id" : 28912,
    "reactomeId" : 10004452,
    "displayName" : "Recruitment of PLC-gamma1 to SLP-76",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 648,
      "y" : 1710
    },
    "minX" : 457,
    "maxX" : 715,
    "minY" : 1704,
    "maxY" : 1770,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 457,
        "y" : 1715
      },
      "to" : {
        "x" : 648,
        "y" : 1710
      }
    }, {
      "from" : {
        "x" : 648,
        "y" : 1710
      },
      "to" : {
        "x" : 715,
        "y" : 1770
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 707,
        "y" : 1768
      },
      "b" : {
        "x" : 715,
        "y" : 1770
      },
      "c" : {
        "x" : 713,
        "y" : 1762
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 713,
        "y" : 1762
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 648,
        "y" : 1710
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 648,
        "y" : 1710
      }
    },
    "inputs" : [ {
      "id" : 28907,
      "points" : [ {
        "x" : 417,
        "y" : 1765
      } ]
    }, {
      "id" : 28913,
      "points" : [ {
        "x" : 403,
        "y" : 1666
      } ]
    } ],
    "outputs" : [ {
      "id" : 28914
    } ]
  }, {
    "id" : 29041,
    "reactomeId" : 10076734,
    "displayName" : "PTPN22 dissociates from CSK",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 270,
      "y" : 378
    },
    "minX" : 260,
    "maxX" : 282,
    "minY" : 361,
    "maxY" : 398,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 260,
        "y" : 398
      },
      "to" : {
        "x" : 270,
        "y" : 378
      }
    }, {
      "from" : {
        "x" : 270,
        "y" : 378
      },
      "to" : {
        "x" : 282,
        "y" : 361
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 270,
        "y" : 378
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 270,
        "y" : 378
      }
    },
    "inputs" : [ {
      "id" : 29042
    } ],
    "outputs" : [ {
      "id" : 29040,
      "points" : [ {
        "x" : 361,
        "y" : 389
      } ]
    }, {
      "id" : 28864,
      "points" : [ {
        "x" : 157,
        "y" : 148
      } ]
    } ]
  }, {
    "id" : 29043,
    "reactomeId" : 10076736,
    "displayName" : "PTPN22 dephosphorylates ZAP70",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 156,
      "y" : 752
    },
    "minX" : 150,
    "maxX" : 162,
    "minY" : 722,
    "maxY" : 782,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 150,
        "y" : 782
      },
      "to" : {
        "x" : 156,
        "y" : 752
      }
    }, {
      "from" : {
        "x" : 156,
        "y" : 752
      },
      "to" : {
        "x" : 159,
        "y" : 722
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 150,
        "y" : 746
      },
      "b" : {
        "x" : 162,
        "y" : 758
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 156,
        "y" : 752
      }
    },
    "inputs" : [ {
      "id" : 28888,
      "points" : [ {
        "x" : 90,
        "y" : 890
      } ]
    }, {
      "id" : 29044,
      "points" : [ {
        "x" : 181,
        "y" : 803
      } ]
    } ],
    "outputs" : [ {
      "id" : 28885,
      "points" : [ {
        "x" : 112,
        "y" : 675
      } ]
    }, {
      "id" : 29045,
      "points" : [ {
        "x" : 209,
        "y" : 705
      } ]
    } ],
    "catalysts" : [ {
      "id" : 29040,
      "points" : [ {
        "x" : 393,
        "y" : 416
      }, {
        "x" : 343,
        "y" : 750
      } ]
    } ]
  }, {
    "id" : 28915,
    "reactomeId" : 10004334,
    "displayName" : "Recruitment of PLC-gamma1 to LAT",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 18,
      "y" : 1630
    },
    "minX" : 12,
    "maxX" : 68,
    "minY" : 1537,
    "maxY" : 1727,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 18,
        "y" : 1537
      },
      "to" : {
        "x" : 18,
        "y" : 1630
      }
    }, {
      "from" : {
        "x" : 18,
        "y" : 1630
      },
      "to" : {
        "x" : 68,
        "y" : 1727
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 61,
        "y" : 1723
      },
      "b" : {
        "x" : 68,
        "y" : 1727
      },
      "c" : {
        "x" : 68,
        "y" : 1719
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 68,
        "y" : 1719
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 18,
        "y" : 1630
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 18,
        "y" : 1630
      }
    },
    "inputs" : [ {
      "id" : 28897,
      "points" : [ {
        "x" : 71,
        "y" : 1447
      } ]
    }, {
      "id" : 28913,
      "points" : [ {
        "x" : 366,
        "y" : 1644
      } ]
    } ],
    "outputs" : [ {
      "id" : 28916
    } ]
  }, {
    "id" : 28917,
    "reactomeId" : 10004436,
    "displayName" : "Phosphorylation of PLC-gamma1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1075,
      "y" : 1748
    },
    "minX" : 1053,
    "maxX" : 1100,
    "minY" : 1742,
    "maxY" : 1754,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1053,
        "y" : 1748
      },
      "to" : {
        "x" : 1075,
        "y" : 1748
      }
    }, {
      "from" : {
        "x" : 1075,
        "y" : 1748
      },
      "to" : {
        "x" : 1100,
        "y" : 1748
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1069,
        "y" : 1742
      },
      "b" : {
        "x" : 1081,
        "y" : 1754
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1075,
        "y" : 1748
      }
    },
    "inputs" : [ {
      "id" : 28918,
      "points" : [ {
        "x" : 964,
        "y" : 1768
      } ]
    }, {
      "id" : 28919,
      "points" : [ {
        "x" : 1020,
        "y" : 1727
      } ],
      "stoichiometry" : 3
    } ],
    "outputs" : [ {
      "id" : 28920,
      "points" : [ {
        "x" : 1160,
        "y" : 1765
      } ]
    }, {
      "id" : 28921,
      "points" : [ {
        "x" : 1153,
        "y" : 1726
      } ],
      "stoichiometry" : 3
    } ],
    "catalysts" : [ {
      "id" : 28922,
      "points" : [ {
        "x" : 1075,
        "y" : 1789
      } ]
    } ],
    "inhibitors" : [ {
      "id" : 28923,
      "points" : [ {
        "x" : 1073,
        "y" : 1645
      } ]
    } ]
  }, {
    "id" : 29046,
    "reactomeId" : 10003161,
    "displayName" : "PTEN dephosphorylates PIP3",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 3098,
      "y" : 1361
    },
    "minX" : 3092,
    "maxX" : 3146,
    "minY" : 1231,
    "maxY" : 1428,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 3146,
        "y" : 1428
      },
      "to" : {
        "x" : 3098,
        "y" : 1361
      }
    }, {
      "from" : {
        "x" : 3098,
        "y" : 1361
      },
      "to" : {
        "x" : 3132,
        "y" : 1231
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3092,
        "y" : 1355
      },
      "b" : {
        "x" : 3104,
        "y" : 1367
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3098,
        "y" : 1361
      }
    },
    "inputs" : [ {
      "id" : 28944,
      "points" : [ {
        "x" : 3195,
        "y" : 1436
      } ]
    }, {
      "id" : 28947,
      "points" : [ {
        "x" : 3168,
        "y" : 1418
      } ]
    } ],
    "outputs" : [ {
      "id" : 29047,
      "points" : [ {
        "x" : 3200,
        "y" : 1212
      } ]
    }, {
      "id" : 28949,
      "points" : [ {
        "x" : 3159,
        "y" : 1254
      } ]
    } ],
    "catalysts" : [ {
      "id" : 29048,
      "points" : [ {
        "x" : 3042,
        "y" : 1358
      } ]
    } ]
  }, {
    "id" : 28924,
    "reactomeId" : 10007155,
    "displayName" : "Disassociation of PLC-gamma1 from LAT",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1915,
      "y" : 1739
    },
    "minX" : 1869,
    "maxX" : 1934,
    "minY" : 1704,
    "maxY" : 1766,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 1869,
        "y" : 1766
      },
      "to" : {
        "x" : 1915,
        "y" : 1739
      }
    }, {
      "from" : {
        "x" : 1915,
        "y" : 1739
      },
      "to" : {
        "x" : 1934,
        "y" : 1704
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 1915,
        "y" : 1739
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 1915,
        "y" : 1739
      }
    },
    "inputs" : [ {
      "id" : 28925
    } ],
    "outputs" : [ {
      "id" : 28926,
      "points" : [ {
        "x" : 2001,
        "y" : 1773
      } ]
    }, {
      "id" : 28897,
      "points" : [ {
        "x" : 124,
        "y" : 1432
      } ]
    } ]
  }, {
    "id" : 28927,
    "reactomeId" : 10007157,
    "displayName" : "Disassociation of PLC-gamma1 from SLP-76",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1745,
      "y" : 1838
    },
    "minX" : 1689,
    "maxX" : 1846,
    "minY" : 1815,
    "maxY" : 1872,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 1689,
        "y" : 1815
      },
      "to" : {
        "x" : 1745,
        "y" : 1838
      }
    }, {
      "from" : {
        "x" : 1745,
        "y" : 1838
      },
      "to" : {
        "x" : 1846,
        "y" : 1872
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 1745,
        "y" : 1838
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 1745,
        "y" : 1838
      }
    },
    "inputs" : [ {
      "id" : 28928
    } ],
    "outputs" : [ {
      "id" : 28926,
      "points" : [ {
        "x" : 1968,
        "y" : 1822
      } ]
    }, {
      "id" : 28907,
      "points" : [ {
        "x" : 435,
        "y" : 1814
      }, {
        "x" : 551,
        "y" : 1885
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 29049,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1658,
      "y" : 935
    },
    "minX" : 75,
    "maxX" : 3241,
    "minY" : 68,
    "maxY" : 1802,
    "prop" : {
      "x" : 75,
      "y" : 68,
      "width" : 3166,
      "height" : 1734
    },
    "textPosition" : {
      "x" : 600,
      "y" : 1426
    },
    "insets" : {
      "x" : 85,
      "y" : 78,
      "width" : 3146,
      "height" : 1714
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 28863, 28864, 28865, 28876, 28877, 28878, 28862, 28875, 28879, 28880, 28867, 28868, 28869, 28870, 28881, 28882, 28866, 28872, 28883, 28884, 28885, 28887, 28873, 28888, 28889, 28890, 28891, 28892, 28893, 28894, 28896, 28897, 28899, 28900, 28901, 28902, 28903, 28904, 28905, 28907, 28906, 28908, 28909, 28911, 28910, 28912, 28913, 28914, 28916, 28917, 28918, 28919, 28920, 28921, 28922, 28924, 28925, 28926, 28928, 28930, 28931, 28932, 28933, 28934, 28937, 28938, 28939, 28940, 28941, 28944, 28945, 28946, 28948, 28950, 28951, 28952, 28953, 28954, 28955, 28956, 28958, 28943, 28942, 29047, 28957, 28959, 28960, 28961, 28962, 28963, 28964, 28965, 28966, 28967, 28968, 28969, 28970, 28971, 28972, 28973, 28974, 28975, 28976, 28977, 28978, 28979, 28980, 28981, 28982, 28983, 28984, 28985, 28986, 28987, 28988, 28989, 28990, 28991, 28992, 28993, 28994, 28995, 28996, 28998, 28999, 29000, 29001, 29002, 29003, 29007, 29005, 29004, 29006, 29008, 29009, 29012, 29010, 29013, 29014, 29015, 28874, 28997, 29011, 29018, 29019, 29020, 29021, 29022, 29023, 29024, 29025, 29026, 29027, 28935, 29052, 29054, 29058, 28886, 28895, 28898, 29017, 29016, 29028, 29029, 29030, 29032, 29031, 29033, 29035, 29050, 29034, 28871, 29038, 29039, 29040, 29041, 29042, 29043, 29044, 29045, 28923, 29048, 29046, 28949, 28947, 29051, 29060, 28936 ]
  }, {
    "id" : 29050,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1096,
      "y" : 647
    },
    "minX" : 983,
    "maxX" : 1209,
    "minY" : 570,
    "maxY" : 725,
    "prop" : {
      "x" : 983,
      "y" : 570,
      "width" : 226,
      "height" : 155
    },
    "textPosition" : {
      "x" : 1053,
      "y" : 656
    },
    "insets" : {
      "x" : 993,
      "y" : 580,
      "width" : 206,
      "height" : 135
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 29036, 29037 ]
  } ],
  "notes" : [ ],
  "links" : [ {
    "id" : 29056,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 3333,
      "y" : 1233
    },
    "minX" : 3245,
    "maxX" : 3339,
    "minY" : 1136,
    "maxY" : 1425,
    "segments" : [ {
      "from" : {
        "x" : 3245,
        "y" : 1425
      },
      "to" : {
        "x" : 3333,
        "y" : 1233
      }
    }, {
      "from" : {
        "x" : 3333,
        "y" : 1233
      },
      "to" : {
        "x" : 3247,
        "y" : 1136
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3327,
        "y" : 1227
      },
      "b" : {
        "x" : 3339,
        "y" : 1239
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3333,
        "y" : 1233
      }
    },
    "inputs" : [ {
      "id" : 28944
    } ],
    "outputs" : [ {
      "id" : 28952
    } ]
  }, {
    "id" : 29057,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 3309,
      "y" : 1228
    },
    "minX" : 3245,
    "maxX" : 3315,
    "minY" : 1136,
    "maxY" : 1242,
    "segments" : [ {
      "from" : {
        "x" : 3276,
        "y" : 1242
      },
      "to" : {
        "x" : 3309,
        "y" : 1228
      }
    }, {
      "from" : {
        "x" : 3309,
        "y" : 1228
      },
      "to" : {
        "x" : 3245,
        "y" : 1136
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 3303,
        "y" : 1222
      },
      "b" : {
        "x" : 3315,
        "y" : 1234
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3309,
        "y" : 1228
      }
    },
    "inputs" : [ {
      "id" : 28948
    } ],
    "outputs" : [ {
      "id" : 28952
    } ]
  }, {
    "id" : 29058,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 813,
      "y" : 1790
    },
    "minX" : 795,
    "maxX" : 831,
    "minY" : 1784,
    "maxY" : 1796,
    "segments" : [ {
      "from" : {
        "x" : 795,
        "y" : 1790
      },
      "to" : {
        "x" : 831,
        "y" : 1790
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 807,
        "y" : 1784
      },
      "b" : {
        "x" : 819,
        "y" : 1796
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 813,
        "y" : 1790
      }
    },
    "inputs" : [ {
      "id" : 28914
    } ],
    "outputs" : [ {
      "id" : 28918
    } ]
  }, {
    "id" : 29059,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 253,
      "y" : 1850
    },
    "minX" : 55,
    "maxX" : 831,
    "minY" : 1755,
    "maxY" : 1887,
    "segments" : [ {
      "from" : {
        "x" : 71,
        "y" : 1755
      },
      "to" : {
        "x" : 55,
        "y" : 1813
      }
    }, {
      "from" : {
        "x" : 55,
        "y" : 1813
      },
      "to" : {
        "x" : 451,
        "y" : 1887
      }
    }, {
      "from" : {
        "x" : 451,
        "y" : 1887
      },
      "to" : {
        "x" : 831,
        "y" : 1805
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 247,
        "y" : 1844
      },
      "b" : {
        "x" : 259,
        "y" : 1856
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 253,
        "y" : 1850
      }
    },
    "inputs" : [ {
      "id" : 28916
    } ],
    "outputs" : [ {
      "id" : 28918
    } ]
  }, {
    "id" : 29060,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 3136,
      "y" : 1453
    },
    "minX" : 3077,
    "maxX" : 3195,
    "minY" : 1447,
    "maxY" : 1459,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 3195,
        "y" : 1447
      },
      "to" : {
        "x" : 3077,
        "y" : 1459
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 3083,
        "y" : 1454
      },
      "b" : {
        "x" : 3077,
        "y" : 1459
      },
      "c" : {
        "x" : 3084,
        "y" : 1462
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 3084,
        "y" : 1462
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 3130,
        "y" : 1447
      },
      "b" : {
        "x" : 3142,
        "y" : 1459
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 3136,
        "y" : 1453
      }
    },
    "inputs" : [ {
      "id" : 28944
    } ],
    "outputs" : [ {
      "id" : 29051
    } ]
  }, {
    "id" : 29052,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1563,
      "y" : 1722
    },
    "minX" : 1302,
    "maxX" : 1763,
    "minY" : 1716,
    "maxY" : 1776,
    "segments" : [ {
      "from" : {
        "x" : 1763,
        "y" : 1776
      },
      "to" : {
        "x" : 1563,
        "y" : 1722
      }
    }, {
      "from" : {
        "x" : 1563,
        "y" : 1722
      },
      "to" : {
        "x" : 1302,
        "y" : 1771
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1557,
        "y" : 1716
      },
      "b" : {
        "x" : 1569,
        "y" : 1728
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1563,
        "y" : 1722
      }
    },
    "inputs" : [ {
      "id" : 28925
    } ],
    "outputs" : [ {
      "id" : 28920
    } ]
  }, {
    "id" : 29053,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1394,
      "y" : 1851
    },
    "minX" : 1302,
    "maxX" : 1569,
    "minY" : 1804,
    "maxY" : 1857,
    "segments" : [ {
      "from" : {
        "x" : 1569,
        "y" : 1804
      },
      "to" : {
        "x" : 1394,
        "y" : 1851
      }
    }, {
      "from" : {
        "x" : 1394,
        "y" : 1851
      },
      "to" : {
        "x" : 1302,
        "y" : 1810
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1388,
        "y" : 1845
      },
      "b" : {
        "x" : 1400,
        "y" : 1857
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1394,
        "y" : 1851
      }
    },
    "inputs" : [ {
      "id" : 28928
    } ],
    "outputs" : [ {
      "id" : 28920
    } ]
  }, {
    "id" : 29054,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 577,
      "y" : 1497
    },
    "minX" : 107,
    "maxX" : 1047,
    "minY" : 1205,
    "maxY" : 1789,
    "segments" : [ {
      "from" : {
        "x" : 107,
        "y" : 1205
      },
      "to" : {
        "x" : 1047,
        "y" : 1789
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 571,
        "y" : 1491
      },
      "b" : {
        "x" : 583,
        "y" : 1503
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 577,
        "y" : 1497
      }
    },
    "inputs" : [ {
      "id" : 28892
    } ],
    "outputs" : [ {
      "id" : 28922
    } ]
  }, {
    "id" : 29055,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 974,
      "y" : 1868
    },
    "minX" : 657,
    "maxX" : 1042,
    "minY" : 1805,
    "maxY" : 1874,
    "segments" : [ {
      "from" : {
        "x" : 657,
        "y" : 1805
      },
      "to" : {
        "x" : 974,
        "y" : 1868
      }
    }, {
      "from" : {
        "x" : 974,
        "y" : 1868
      },
      "to" : {
        "x" : 1042,
        "y" : 1837
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 968,
        "y" : 1862
      },
      "b" : {
        "x" : 980,
        "y" : 1874
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 974,
        "y" : 1868
      }
    },
    "inputs" : [ {
      "id" : 28911
    } ],
    "outputs" : [ {
      "id" : 28922
    } ]
  } ],
  "shadows" : [ {
    "id" : 29061,
    "reactomeId" : 10099759,
    "displayName" : "Downstream TCR signaling",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 2152,
      "y" : 911
    },
    "minX" : 994,
    "maxX" : 3311,
    "minY" : 39,
    "maxY" : 1784,
    "prop" : {
      "x" : 1017,
      "y" : 39,
      "width" : 2294,
      "height" : 487
    },
    "points" : [ {
      "x" : 994,
      "y" : 39
    }, {
      "x" : 3311,
      "y" : 39
    }, {
      "x" : 3311,
      "y" : 1784
    }, {
      "x" : 994,
      "y" : 1784
    } ],
    "colour" : "#4684ee"
  }, {
    "id" : 29062,
    "reactomeId" : 10099803,
    "displayName" : "Phosphorylation of CD3 and TCR zeta chains",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 512,
      "y" : 278
    },
    "minX" : 8,
    "maxX" : 1017,
    "minY" : 30,
    "maxY" : 526,
    "prop" : {
      "x" : 437,
      "y" : 202,
      "width" : 557,
      "height" : 324
    },
    "points" : [ {
      "x" : 8,
      "y" : 30
    }, {
      "x" : 1017,
      "y" : 30
    }, {
      "x" : 1017,
      "y" : 526
    }, {
      "x" : 8,
      "y" : 526
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 29063,
    "reactomeId" : 10099805,
    "displayName" : "Translocation of ZAP-70 to Immunological synapse",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 222,
      "y" : 707
    },
    "minX" : 8,
    "maxX" : 437,
    "minY" : 202,
    "maxY" : 1212,
    "prop" : {
      "x" : 8,
      "y" : 526,
      "width" : 429,
      "height" : 385
    },
    "points" : [ {
      "x" : 8,
      "y" : 202
    }, {
      "x" : 437,
      "y" : 202
    }, {
      "x" : 437,
      "y" : 1212
    }, {
      "x" : 8,
      "y" : 1212
    } ],
    "colour" : "#008000"
  }, {
    "id" : 29064,
    "reactomeId" : 10099807,
    "displayName" : "Generation of second messenger molecules",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1278,
      "y" : 1396
    },
    "minX" : 2,
    "maxX" : 2555,
    "minY" : 911,
    "maxY" : 1882,
    "prop" : {
      "x" : 2,
      "y" : 1212,
      "width" : 992,
      "height" : 572
    },
    "points" : [ {
      "x" : 2,
      "y" : 911
    }, {
      "x" : 2555,
      "y" : 911
    }, {
      "x" : 2555,
      "y" : 1882
    }, {
      "x" : 2,
      "y" : 1882
    } ],
    "colour" : "#666666"
  } ],
  "minX" : 0,
  "maxX" : 3339,
  "minY" : 0,
  "maxY" : 1887,
  "disease" : false
}