{
  "dbId" : 9860276,
  "stId" : "R-HSA-9860276",
  "speciesName" : "Homo sapiens",
  "nodes" : [ {
    "dbId" : 9860274,
    "stId" : "R-HSA-9860274",
    "displayName" : "p-S446-IRF5:p-S446-IRF5 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 48887,
    "diagramIds" : [ 27 ],
    "parents" : [ ],
    "children" : [ 9860304 ]
  }, {
    "dbId" : 9860275,
    "stId" : "R-HSA-9860275",
    "displayName" : "SLC15A4:SLC15A4 [endolysosome membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48887,
    "diagramIds" : [ 4 ],
    "parents" : [ ],
    "children" : [ 9860282 ]
  }, {
    "dbId" : 9860304,
    "stId" : "R-HSA-9860304",
    "displayName" : "p-S446-IRF5 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48887,
    "identifier" : "Q13568",
    "standardIdentifier" : "uniprot:Q13568",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IRF5" ],
    "parents" : [ 9860274 ],
    "children" : [ ]
  }, {
    "dbId" : 202506,
    "stId" : "R-HSA-202506",
    "displayName" : "p-S177,S181-IKBKB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48887,
    "identifier" : "O14920",
    "standardIdentifier" : "uniprot:O14920",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IKBKB", "IKKB" ],
    "parents" : [ 202513 ],
    "children" : [ ]
  }, {
    "dbId" : 9860255,
    "stId" : "R-HSA-9860255",
    "displayName" : "SLC15A4:p-S-TASL:IRF5 [endolysosome membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48887,
    "diagramIds" : [ 19 ],
    "parents" : [ ],
    "children" : [ 9860291, 1015676 ]
  }, {
    "dbId" : 168104,
    "stId" : "R-HSA-168104",
    "displayName" : "CHUK [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48887,
    "identifier" : "O15111",
    "standardIdentifier" : "uniprot:O15111",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CHUK", "IKKA", "TCF16" ],
    "parents" : [ 202513 ],
    "children" : [ ]
  }, {
    "dbId" : 9860284,
    "stId" : "R-HSA-9860284",
    "displayName" : "p-S294-TASL [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48887,
    "identifier" : "Q9HAI6",
    "standardIdentifier" : "uniprot:Q9HAI6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TASL", "CXorf21" ],
    "parents" : [ 9860291 ],
    "children" : [ ]
  }, {
    "dbId" : 9860285,
    "stId" : "R-HSA-9860285",
    "displayName" : "SLC15A4:TASL [endolysosome membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48887,
    "diagramIds" : [ 6 ],
    "parents" : [ ],
    "children" : [ 9860282, 9860303 ]
  }, {
    "dbId" : 9860282,
    "stId" : "R-HSA-9860282",
    "displayName" : "SLC15A4 [endolysosome membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48887,
    "identifier" : "Q8N697",
    "standardIdentifier" : "uniprot:Q8N697",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "SLC15A4", "PHT1", "PTR4", "FP12591" ],
    "parents" : [ 9860291, 9860285, 9860275 ],
    "children" : [ ]
  }, {
    "dbId" : 168108,
    "stId" : "R-HSA-168108",
    "displayName" : "IKBKG [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48887,
    "identifier" : "Q9Y6K9",
    "standardIdentifier" : "uniprot:Q9Y6K9",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IKBKG", "FIP3", "NEMO" ],
    "parents" : [ 202513 ],
    "children" : [ ]
  }, {
    "dbId" : 202513,
    "stId" : "R-HSA-202513",
    "displayName" : "CHUK:p-S177,S181-IKBKB:IKBKG [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48887,
    "diagramIds" : [ 22 ],
    "parents" : [ ],
    "children" : [ 168108, 168104, 202506 ]
  }, {
    "dbId" : 1015676,
    "stId" : "R-HSA-1015676",
    "displayName" : "IRF5 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48887,
    "diagramIds" : [ 18 ],
    "identifier" : "Q13568",
    "standardIdentifier" : "uniprot:Q13568",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IRF5" ],
    "parents" : [ 9860255 ],
    "children" : [ ]
  }, {
    "dbId" : 9860291,
    "stId" : "R-HSA-9860291",
    "displayName" : "SLC15A4:p-S294-TASL [endolysosome membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 48887,
    "diagramIds" : [ 9 ],
    "parents" : [ 9860255 ],
    "children" : [ 9860282, 9860284 ]
  }, {
    "dbId" : 9860257,
    "stId" : "R-HSA-9860257",
    "displayName" : "p-S446-IRF5:p-S446-IRF5 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 48887,
    "diagramIds" : [ 24 ],
    "parents" : [ ],
    "children" : [ 9860271 ]
  }, {
    "dbId" : 9860271,
    "stId" : "R-HSA-9860271",
    "displayName" : "p-S446-IRF5 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48887,
    "diagramIds" : [ 21 ],
    "identifier" : "Q13568",
    "standardIdentifier" : "uniprot:Q13568",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IRF5" ],
    "parents" : [ 9860257 ],
    "children" : [ ]
  }, {
    "dbId" : 9860303,
    "stId" : "R-HSA-9860303",
    "displayName" : "TASL [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 48887,
    "diagramIds" : [ 5 ],
    "identifier" : "Q9HAI6",
    "standardIdentifier" : "uniprot:Q9HAI6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TASL", "CXorf21" ],
    "parents" : [ 9860285 ],
    "children" : [ ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 8 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 10 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 9860278,
    "stId" : "R-HSA-9860278",
    "displayName" : "p-S446-IRF5 dimer translocates to the nucleus",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 9860273 ],
    "inputs" : [ 9860257 ],
    "outputs" : [ 9860274 ],
    "efs" : [ ],
    "diagramIds" : [ 26 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 9860295,
    "stId" : "R-HSA-9860295",
    "displayName" : "SLC15A4 binds TASL",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 9860264 ],
    "inputs" : [ 9860303, 9860275 ],
    "outputs" : [ 9860285 ],
    "efs" : [ ],
    "diagramIds" : [ 3 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 9860292,
    "stId" : "R-HSA-9860292",
    "displayName" : "Activated IKBKB phosphorylates IRF5",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 9860290 ],
    "following" : [ 9860273 ],
    "inputs" : [ 9860255 ],
    "outputs" : [ 9860271, 9860291 ],
    "catalysts" : [ 202513 ],
    "efs" : [ ],
    "diagramIds" : [ 20 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 9860290,
    "stId" : "R-HSA-9860290",
    "displayName" : "TASL recruits IRF5",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 9860264 ],
    "following" : [ 9860292 ],
    "inputs" : [ 9860291, 1015676 ],
    "outputs" : [ 9860255 ],
    "efs" : [ ],
    "diagramIds" : [ 17 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 9860273,
    "stId" : "R-HSA-9860273",
    "displayName" : "Dimerization of p-S446-IRF5",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 9860292 ],
    "following" : [ 9860278 ],
    "inputs" : [ 9860271 ],
    "outputs" : [ 9860257 ],
    "efs" : [ ],
    "diagramIds" : [ 23 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 9860264,
    "stId" : "R-HSA-9860264",
    "displayName" : "TASL is phosphorylated",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 9860295 ],
    "following" : [ 9860290 ],
    "inputs" : [ 9860285, 113592 ],
    "outputs" : [ 29370, 9860291 ],
    "efs" : [ ],
    "diagramIds" : [ 7 ],
    "entityFunctionalStatus" : [ ]
  } ]
}