{
  "dbId" : 71262,
  "stableId" : "R-HSA-71262",
  "displayName" : "Carnitine synthesis",
  "nodes" : [ {
    "id" : 594,
    "reactomeId" : 113533,
    "displayName" : "O2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 512,
      "y" : 122
    },
    "minX" : 495,
    "maxX" : 555,
    "minY" : 106,
    "maxY" : 144,
    "prop" : {
      "x" : 495,
      "y" : 107,
      "width" : 34,
      "height" : 30
    },
    "textPosition" : {
      "x" : 499,
      "y" : 111
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 524,
          "y" : 112
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 524,
          "y" : 112
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2546,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 532,
          "y" : 130
        },
        "to" : {
          "x" : 555,
          "y" : 144
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 595,
    "reactomeId" : 35139,
    "displayName" : "TMLYS",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 554,
      "y" : 83
    },
    "minX" : 527,
    "maxX" : 583,
    "minY" : 67,
    "maxY" : 144,
    "prop" : {
      "x" : 527,
      "y" : 68,
      "width" : 55,
      "height" : 30
    },
    "textPosition" : {
      "x" : 531,
      "y" : 72
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 577,
          "y" : 73
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 577,
          "y" : 73
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2546,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 554,
          "y" : 101
        },
        "to" : {
          "x" : 555,
          "y" : 144
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 596,
    "reactomeId" : 113546,
    "displayName" : "HTMLYS",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 557,
      "y" : 251
    },
    "minX" : 525,
    "maxX" : 590,
    "minY" : 192,
    "maxY" : 266,
    "prop" : {
      "x" : 525,
      "y" : 236,
      "width" : 64,
      "height" : 30
    },
    "textPosition" : {
      "x" : 529,
      "y" : 240
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 584,
          "y" : 241
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 584,
          "y" : 241
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2546,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 556,
          "y" : 233
        },
        "to" : {
          "x" : 555,
          "y" : 192
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 552,
          "y" : 226
        },
        "b" : {
          "x" : 556,
          "y" : 233
        },
        "c" : {
          "x" : 560,
          "y" : 226
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 560,
          "y" : 226
        }
      }
    }, {
      "edgeId" : 2788,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 597,
    "reactomeId" : 113536,
    "displayName" : "SUCCA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 623,
      "y" : 232
    },
    "minX" : 555,
    "maxX" : 652,
    "minY" : 192,
    "maxY" : 247,
    "prop" : {
      "x" : 595,
      "y" : 217,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 598,
      "y" : 221
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 646,
          "y" : 222
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 646,
          "y" : 222
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2546,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 597,
          "y" : 214
        },
        "to" : {
          "x" : 555,
          "y" : 192
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 589,
          "y" : 214
        },
        "b" : {
          "x" : 597,
          "y" : 214
        },
        "c" : {
          "x" : 593,
          "y" : 207
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 593,
          "y" : 207
        }
      }
    } ]
  }, {
    "id" : 598,
    "reactomeId" : 71098,
    "displayName" : "TMLHE:AscH-:Fe2+ dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 664,
      "y" : 167
    },
    "minX" : 564,
    "maxX" : 736,
    "minY" : 143,
    "maxY" : 185,
    "prop" : {
      "x" : 598,
      "y" : 149,
      "width" : 132,
      "height" : 36
    },
    "textPosition" : {
      "x" : 600,
      "y" : 150
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 730,
          "y" : 149
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 730,
          "y" : 149
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2546,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 595,
          "y" : 167
        },
        "to" : {
          "x" : 572,
          "y" : 168
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 568,
          "y" : 168
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 568,
          "y" : 168
        }
      }
    } ]
  }, {
    "id" : 600,
    "reactomeId" : 29376,
    "displayName" : "CO2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 513,
      "y" : 204
    },
    "minX" : 492,
    "maxX" : 555,
    "minY" : 188,
    "maxY" : 219,
    "prop" : {
      "x" : 492,
      "y" : 189,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 497,
      "y" : 193
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 530,
          "y" : 194
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 530,
          "y" : 194
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2546,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 538,
          "y" : 197
        },
        "to" : {
          "x" : 555,
          "y" : 192
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 544,
          "y" : 191
        },
        "b" : {
          "x" : 538,
          "y" : 197
        },
        "c" : {
          "x" : 546,
          "y" : 199
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 546,
          "y" : 199
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 602,
    "reactomeId" : 113594,
    "displayName" : "2OG",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 637,
      "y" : 113
    },
    "minX" : 555,
    "maxX" : 660,
    "minY" : 97,
    "maxY" : 144,
    "prop" : {
      "x" : 615,
      "y" : 98,
      "width" : 44,
      "height" : 30
    },
    "textPosition" : {
      "x" : 620,
      "y" : 102
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 654,
          "y" : 103
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 654,
          "y" : 103
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2546,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 612,
          "y" : 121
        },
        "to" : {
          "x" : 555,
          "y" : 144
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 604,
    "reactomeId" : 31503,
    "displayName" : "HTMLYS",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 305,
      "y" : 250
    },
    "minX" : 273,
    "maxX" : 338,
    "minY" : 234,
    "maxY" : 265,
    "prop" : {
      "x" : 273,
      "y" : 235,
      "width" : 64,
      "height" : 30
    },
    "textPosition" : {
      "x" : 277,
      "y" : 239
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 332,
          "y" : 240
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 332,
          "y" : 240
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2788,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 2549,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 605,
    "reactomeId" : 29424,
    "displayName" : "Gly",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 364,
      "y" : 355
    },
    "minX" : 305,
    "maxX" : 383,
    "minY" : 337,
    "maxY" : 370,
    "prop" : {
      "x" : 347,
      "y" : 340,
      "width" : 35,
      "height" : 30
    },
    "textPosition" : {
      "x" : 351,
      "y" : 344
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 377,
          "y" : 345
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 377,
          "y" : 345
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2549,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 344,
          "y" : 349
        },
        "to" : {
          "x" : 305,
          "y" : 337
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 336,
          "y" : 351
        },
        "b" : {
          "x" : 344,
          "y" : 349
        },
        "c" : {
          "x" : 339,
          "y" : 343
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 339,
          "y" : 343
        }
      }
    } ]
  }, {
    "id" : 606,
    "reactomeId" : 31311,
    "displayName" : "TEABL",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 305,
      "y" : 375
    },
    "minX" : 278,
    "maxX" : 333,
    "minY" : 337,
    "maxY" : 441,
    "prop" : {
      "x" : 278,
      "y" : 360,
      "width" : 54,
      "height" : 30
    },
    "textPosition" : {
      "x" : 282,
      "y" : 364
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 327,
          "y" : 365
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 327,
          "y" : 365
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2549,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 305,
          "y" : 357
        },
        "to" : {
          "x" : 305,
          "y" : 337
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 301,
          "y" : 350
        },
        "b" : {
          "x" : 305,
          "y" : 357
        },
        "c" : {
          "x" : 309,
          "y" : 350
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 309,
          "y" : 350
        }
      }
    }, {
      "edgeId" : 2550,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 305,
          "y" : 393
        },
        "to" : {
          "x" : 306,
          "y" : 441
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 607,
    "reactomeId" : 71243,
    "displayName" : "SHMT1 tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 217,
      "y" : 306
    },
    "minX" : 178,
    "maxX" : 297,
    "minY" : 282,
    "maxY" : 324,
    "prop" : {
      "x" : 178,
      "y" : 288,
      "width" : 79,
      "height" : 36
    },
    "textPosition" : {
      "x" : 186,
      "y" : 289
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 257,
          "y" : 288
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 257,
          "y" : 288
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2549,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 260,
          "y" : 305
        },
        "to" : {
          "x" : 289,
          "y" : 304
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 293,
          "y" : 304
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 293,
          "y" : 304
        }
      }
    } ]
  }, {
    "id" : 609,
    "reactomeId" : 31369,
    "displayName" : "TEABT",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 305,
      "y" : 590
    },
    "minX" : 277,
    "maxX" : 334,
    "minY" : 515,
    "maxY" : 631,
    "prop" : {
      "x" : 277,
      "y" : 575,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 282,
      "y" : 579
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 328,
          "y" : 580
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 328,
          "y" : 580
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2550,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 305,
          "y" : 572
        },
        "to" : {
          "x" : 307,
          "y" : 515
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 301,
          "y" : 565
        },
        "b" : {
          "x" : 305,
          "y" : 572
        },
        "c" : {
          "x" : 309,
          "y" : 565
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 309,
          "y" : 565
        }
      }
    }, {
      "edgeId" : 2552,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 305,
          "y" : 608
        },
        "to" : {
          "x" : 305,
          "y" : 631
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 610,
    "reactomeId" : 71258,
    "displayName" : "ALDH9A1 tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 392,
      "y" : 479
    },
    "minX" : 314,
    "maxX" : 439,
    "minY" : 456,
    "maxY" : 496,
    "prop" : {
      "x" : 351,
      "y" : 462,
      "width" : 82,
      "height" : 34
    },
    "textPosition" : {
      "x" : 358,
      "y" : 461
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 433,
          "y" : 462
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 433,
          "y" : 462
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2550,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 348,
          "y" : 477
        },
        "to" : {
          "x" : 322,
          "y" : 476
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 318,
          "y" : 476
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 318,
          "y" : 476
        }
      }
    } ]
  }, {
    "id" : 2786,
    "reactomeId" : 164988,
    "displayName" : "CAR",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 20,
      "y" : 760
    },
    "minX" : 0,
    "maxX" : 42,
    "minY" : 744,
    "maxY" : 775,
    "prop" : {
      "x" : 0,
      "y" : 745,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 4,
      "y" : 749
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 36,
          "y" : 750
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 36,
          "y" : 750
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2785,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 2787,
    "reactomeId" : 165022,
    "displayName" : "carnitine exporter",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 100,
      "y" : 811
    },
    "minX" : 42,
    "maxX" : 158,
    "minY" : 767,
    "maxY" : 822,
    "prop" : {
      "x" : 42,
      "y" : 800,
      "width" : 116,
      "height" : 22
    },
    "textPosition" : {
      "x" : 66,
      "y" : 794
    },
    "connectors" : [ {
      "edgeId" : 2785,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 100,
          "y" : 797
        },
        "to" : {
          "x" : 100,
          "y" : 775
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 100,
          "y" : 771
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 100,
          "y" : 771
        }
      }
    } ]
  }, {
    "id" : 612,
    "reactomeId" : 73473,
    "displayName" : "NADH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 376,
      "y" : 548
    },
    "minX" : 307,
    "maxX" : 404,
    "minY" : 515,
    "maxY" : 563,
    "prop" : {
      "x" : 350,
      "y" : 533,
      "width" : 53,
      "height" : 30
    },
    "textPosition" : {
      "x" : 355,
      "y" : 537
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 398,
          "y" : 538
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 398,
          "y" : 538
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2550,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 347,
          "y" : 535
        },
        "to" : {
          "x" : 307,
          "y" : 515
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 339,
          "y" : 535
        },
        "b" : {
          "x" : 347,
          "y" : 535
        },
        "c" : {
          "x" : 343,
          "y" : 528
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 343,
          "y" : 528
        }
      }
    } ]
  }, {
    "id" : 616,
    "reactomeId" : 29360,
    "displayName" : "NAD+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 358,
      "y" : 427
    },
    "minX" : 306,
    "maxX" : 386,
    "minY" : 411,
    "maxY" : 442,
    "prop" : {
      "x" : 331,
      "y" : 412,
      "width" : 54,
      "height" : 30
    },
    "textPosition" : {
      "x" : 336,
      "y" : 416
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 380,
          "y" : 417
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 380,
          "y" : 417
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2550,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 328,
          "y" : 434
        },
        "to" : {
          "x" : 306,
          "y" : 441
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 618,
    "reactomeId" : 30235,
    "displayName" : "CAR",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 305,
      "y" : 761
    },
    "minX" : 285,
    "maxX" : 327,
    "minY" : 706,
    "maxY" : 776,
    "prop" : {
      "x" : 285,
      "y" : 746,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 289,
      "y" : 750
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 321,
          "y" : 751
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 321,
          "y" : 751
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2785,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 2552,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 305,
          "y" : 743
        },
        "to" : {
          "x" : 305,
          "y" : 706
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 301,
          "y" : 736
        },
        "b" : {
          "x" : 305,
          "y" : 743
        },
        "c" : {
          "x" : 309,
          "y" : 736
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 309,
          "y" : 736
        }
      }
    } ]
  }, {
    "id" : 619,
    "reactomeId" : 29434,
    "displayName" : "SUCCA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 256,
      "y" : 737
    },
    "minX" : 228,
    "maxX" : 305,
    "minY" : 706,
    "maxY" : 752,
    "prop" : {
      "x" : 228,
      "y" : 722,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 231,
      "y" : 726
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 279,
          "y" : 727
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 279,
          "y" : 727
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2552,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 279,
          "y" : 719
        },
        "to" : {
          "x" : 305,
          "y" : 706
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 283,
          "y" : 712
        },
        "b" : {
          "x" : 279,
          "y" : 719
        },
        "c" : {
          "x" : 287,
          "y" : 719
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 287,
          "y" : 719
        }
      }
    } ]
  }, {
    "id" : 620,
    "reactomeId" : 71107,
    "displayName" : "BBOX1:AscH-:Fe2+ dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 412,
      "y" : 668
    },
    "minX" : 313,
    "maxX" : 484,
    "minY" : 644,
    "maxY" : 686,
    "prop" : {
      "x" : 347,
      "y" : 650,
      "width" : 131,
      "height" : 36
    },
    "textPosition" : {
      "x" : 348,
      "y" : 651
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 478,
          "y" : 650
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 478,
          "y" : 650
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2552,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 344,
          "y" : 667
        },
        "to" : {
          "x" : 321,
          "y" : 667
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 317,
          "y" : 667
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 317,
          "y" : 667
        }
      }
    } ]
  }, {
    "id" : 622,
    "reactomeId" : 113528,
    "displayName" : "CO2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 376,
      "y" : 733
    },
    "minX" : 305,
    "maxX" : 399,
    "minY" : 706,
    "maxY" : 748,
    "prop" : {
      "x" : 355,
      "y" : 718,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 360,
      "y" : 722
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 393,
          "y" : 723
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 393,
          "y" : 723
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2552,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 352,
          "y" : 724
        },
        "to" : {
          "x" : 305,
          "y" : 706
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 344,
          "y" : 725
        },
        "b" : {
          "x" : 352,
          "y" : 724
        },
        "c" : {
          "x" : 347,
          "y" : 718
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 347,
          "y" : 718
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 1006,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 255,
      "y" : 541
    },
    "minX" : 237,
    "maxX" : 307,
    "minY" : 515,
    "maxY" : 556,
    "prop" : {
      "x" : 237,
      "y" : 526,
      "width" : 36,
      "height" : 30
    },
    "textPosition" : {
      "x" : 241,
      "y" : 530
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 268,
          "y" : 531
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 268,
          "y" : 531
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2550,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 276,
          "y" : 532
        },
        "to" : {
          "x" : 307,
          "y" : 515
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 285,
            "y" : 517
          },
          "b" : {
            "x" : 297,
            "y" : 529
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 291,
            "y" : 523
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 280,
          "y" : 525
        },
        "b" : {
          "x" : 276,
          "y" : 532
        },
        "c" : {
          "x" : 284,
          "y" : 532
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 284,
          "y" : 532
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 624,
    "reactomeId" : 29406,
    "displayName" : "2OG",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 256,
      "y" : 620
    },
    "minX" : 234,
    "maxX" : 305,
    "minY" : 604,
    "maxY" : 635,
    "prop" : {
      "x" : 234,
      "y" : 605,
      "width" : 44,
      "height" : 30
    },
    "textPosition" : {
      "x" : 239,
      "y" : 609
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 273,
          "y" : 610
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 273,
          "y" : 610
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2552,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 281,
          "y" : 624
        },
        "to" : {
          "x" : 305,
          "y" : 631
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 626,
    "reactomeId" : 29368,
    "displayName" : "O2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 360,
      "y" : 618
    },
    "minX" : 305,
    "maxX" : 378,
    "minY" : 602,
    "maxY" : 633,
    "prop" : {
      "x" : 343,
      "y" : 603,
      "width" : 34,
      "height" : 30
    },
    "textPosition" : {
      "x" : 347,
      "y" : 607
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 372,
          "y" : 608
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 372,
          "y" : 608
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2552,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 340,
          "y" : 622
        },
        "to" : {
          "x" : 305,
          "y" : 631
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 957,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 256,
      "y" : 428
    },
    "minX" : 234,
    "maxX" : 306,
    "minY" : 412,
    "maxY" : 443,
    "prop" : {
      "x" : 234,
      "y" : 413,
      "width" : 44,
      "height" : 30
    },
    "textPosition" : {
      "x" : 239,
      "y" : 417
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 273,
          "y" : 418
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 273,
          "y" : 418
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2550,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 281,
          "y" : 433
        },
        "to" : {
          "x" : 306,
          "y" : 441
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  } ],
  "edges" : [ {
    "id" : 2785,
    "reactomeId" : 164967,
    "displayName" : "Unknown carnitine exporter transports CAR from the cytosol to the extracellular space",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 100,
      "y" : 759
    },
    "minX" : 44,
    "maxX" : 282,
    "minY" : 753,
    "maxY" : 765,
    "reactionType" : "uncertain",
    "segments" : [ {
      "from" : {
        "x" : 282,
        "y" : 760
      },
      "to" : {
        "x" : 100,
        "y" : 759
      }
    }, {
      "from" : {
        "x" : 100,
        "y" : 759
      },
      "to" : {
        "x" : 44,
        "y" : 759
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 51,
        "y" : 755
      },
      "b" : {
        "x" : 44,
        "y" : 759
      },
      "c" : {
        "x" : 51,
        "y" : 763
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 51,
        "y" : 763
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 94,
        "y" : 753
      },
      "b" : {
        "x" : 106,
        "y" : 765
      },
      "s" : "?",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 100,
        "y" : 759
      }
    },
    "inputs" : [ {
      "id" : 618
    } ],
    "outputs" : [ {
      "id" : 2786
    } ],
    "catalysts" : [ {
      "id" : 2787,
      "points" : [ {
        "x" : 100,
        "y" : 797
      } ]
    } ]
  }, {
    "id" : 2546,
    "reactomeId" : 71241,
    "displayName" : "TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 556,
      "y" : 168
    },
    "minX" : 550,
    "maxX" : 562,
    "minY" : 144,
    "maxY" : 192,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 555,
        "y" : 144
      },
      "to" : {
        "x" : 556,
        "y" : 168
      }
    }, {
      "from" : {
        "x" : 556,
        "y" : 168
      },
      "to" : {
        "x" : 555,
        "y" : 192
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 550,
        "y" : 162
      },
      "b" : {
        "x" : 562,
        "y" : 174
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 556,
        "y" : 168
      }
    },
    "inputs" : [ {
      "id" : 594,
      "points" : [ {
        "x" : 532,
        "y" : 130
      } ]
    }, {
      "id" : 595,
      "points" : [ {
        "x" : 554,
        "y" : 101
      } ]
    }, {
      "id" : 602,
      "points" : [ {
        "x" : 612,
        "y" : 121
      } ]
    } ],
    "outputs" : [ {
      "id" : 596,
      "points" : [ {
        "x" : 556,
        "y" : 233
      } ]
    }, {
      "id" : 597,
      "points" : [ {
        "x" : 597,
        "y" : 214
      } ]
    }, {
      "id" : 600,
      "points" : [ {
        "x" : 538,
        "y" : 197
      } ]
    } ],
    "catalysts" : [ {
      "id" : 598,
      "points" : [ {
        "x" : 595,
        "y" : 167
      } ]
    } ]
  }, {
    "id" : 2788,
    "reactomeId" : 8949413,
    "displayName" : "HTMLYS translocates from the mitochondrial matrix to the cytosol",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 463,
      "y" : 249
    },
    "minX" : 340,
    "maxX" : 522,
    "minY" : 243,
    "maxY" : 255,
    "reactionType" : "uncertain",
    "segments" : [ {
      "from" : {
        "x" : 522,
        "y" : 250
      },
      "to" : {
        "x" : 463,
        "y" : 249
      }
    }, {
      "from" : {
        "x" : 463,
        "y" : 249
      },
      "to" : {
        "x" : 340,
        "y" : 249
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 347,
        "y" : 245
      },
      "b" : {
        "x" : 340,
        "y" : 249
      },
      "c" : {
        "x" : 347,
        "y" : 253
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 347,
        "y" : 253
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 457,
        "y" : 243
      },
      "b" : {
        "x" : 469,
        "y" : 255
      },
      "s" : "?",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 463,
        "y" : 249
      }
    },
    "inputs" : [ {
      "id" : 596
    } ],
    "outputs" : [ {
      "id" : 604
    } ]
  }, {
    "id" : 2549,
    "reactomeId" : 71249,
    "displayName" : "SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 305,
      "y" : 304
    },
    "minX" : 299,
    "maxX" : 311,
    "minY" : 268,
    "maxY" : 337,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 305,
        "y" : 268
      },
      "to" : {
        "x" : 305,
        "y" : 304
      }
    }, {
      "from" : {
        "x" : 305,
        "y" : 304
      },
      "to" : {
        "x" : 305,
        "y" : 337
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 299,
        "y" : 298
      },
      "b" : {
        "x" : 311,
        "y" : 310
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 305,
        "y" : 304
      }
    },
    "inputs" : [ {
      "id" : 604
    } ],
    "outputs" : [ {
      "id" : 605,
      "points" : [ {
        "x" : 344,
        "y" : 349
      } ]
    }, {
      "id" : 606,
      "points" : [ {
        "x" : 305,
        "y" : 357
      } ]
    } ],
    "catalysts" : [ {
      "id" : 607,
      "points" : [ {
        "x" : 260,
        "y" : 305
      } ]
    } ]
  }, {
    "id" : 2550,
    "reactomeId" : 71260,
    "displayName" : "ALDH9A1 tetramer dehydrogenates TEABL to form TEABT",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 306,
      "y" : 476
    },
    "minX" : 300,
    "maxX" : 312,
    "minY" : 441,
    "maxY" : 515,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 306,
        "y" : 441
      },
      "to" : {
        "x" : 306,
        "y" : 476
      }
    }, {
      "from" : {
        "x" : 306,
        "y" : 476
      },
      "to" : {
        "x" : 307,
        "y" : 515
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 300,
        "y" : 470
      },
      "b" : {
        "x" : 312,
        "y" : 482
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 306,
        "y" : 476
      }
    },
    "inputs" : [ {
      "id" : 606,
      "points" : [ {
        "x" : 305,
        "y" : 393
      } ]
    }, {
      "id" : 616,
      "points" : [ {
        "x" : 328,
        "y" : 434
      } ]
    }, {
      "id" : 957,
      "points" : [ {
        "x" : 281,
        "y" : 433
      } ]
    } ],
    "outputs" : [ {
      "id" : 1006,
      "points" : [ {
        "x" : 276,
        "y" : 532
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 609,
      "points" : [ {
        "x" : 305,
        "y" : 572
      } ]
    }, {
      "id" : 612,
      "points" : [ {
        "x" : 347,
        "y" : 535
      } ]
    } ],
    "catalysts" : [ {
      "id" : 610,
      "points" : [ {
        "x" : 348,
        "y" : 477
      } ]
    } ]
  }, {
    "id" : 2552,
    "reactomeId" : 71261,
    "displayName" : "BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 305,
      "y" : 667
    },
    "minX" : 299,
    "maxX" : 311,
    "minY" : 631,
    "maxY" : 706,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 305,
        "y" : 631
      },
      "to" : {
        "x" : 305,
        "y" : 667
      }
    }, {
      "from" : {
        "x" : 305,
        "y" : 667
      },
      "to" : {
        "x" : 305,
        "y" : 706
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 299,
        "y" : 661
      },
      "b" : {
        "x" : 311,
        "y" : 673
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 305,
        "y" : 667
      }
    },
    "inputs" : [ {
      "id" : 609,
      "points" : [ {
        "x" : 305,
        "y" : 608
      } ]
    }, {
      "id" : 626,
      "points" : [ {
        "x" : 340,
        "y" : 622
      } ]
    }, {
      "id" : 624,
      "points" : [ {
        "x" : 281,
        "y" : 624
      } ]
    } ],
    "outputs" : [ {
      "id" : 619,
      "points" : [ {
        "x" : 279,
        "y" : 719
      } ]
    }, {
      "id" : 618,
      "points" : [ {
        "x" : 305,
        "y" : 743
      } ]
    }, {
      "id" : 622,
      "points" : [ {
        "x" : 352,
        "y" : 724
      } ]
    } ],
    "catalysts" : [ {
      "id" : 620,
      "points" : [ {
        "x" : 344,
        "y" : 667
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 16,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 457,
      "y" : 432
    },
    "minX" : 94,
    "maxX" : 820,
    "minY" : 0,
    "maxY" : 865,
    "prop" : {
      "x" : 94,
      "y" : 0,
      "width" : 726,
      "height" : 865
    },
    "textPosition" : {
      "x" : 741,
      "y" : 774
    },
    "insets" : {
      "x" : 103,
      "y" : 7,
      "width" : 705,
      "height" : 846
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 604, 605, 606, 607, 609, 610, 612, 616, 618, 619, 620, 622, 624, 626, 17, 957, 1006, 2549, 2550, 2552, 2785, 2787 ]
  }, {
    "id" : 17,
    "reactomeId" : 5460,
    "displayName" : "mitochondrial matrix",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 607,
      "y" : 193
    },
    "minX" : 457,
    "maxX" : 758,
    "minY" : 33,
    "maxY" : 353,
    "prop" : {
      "x" : 457,
      "y" : 33,
      "width" : 301,
      "height" : 320
    },
    "textPosition" : {
      "x" : 480,
      "y" : 282
    },
    "insets" : {
      "x" : 467,
      "y" : 42,
      "width" : 278,
      "height" : 301
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 594, 595, 596, 597, 598, 600, 602, 2546, 2788 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 820,
  "minY" : 0,
  "maxY" : 865,
  "disease" : false
}