{
  "dbId" : 428359,
  "stableId" : "R-HSA-428359",
  "displayName" : "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA",
  "nodes" : [ {
    "id" : 3,
    "reactomeId" : 428308,
    "displayName" : "RNAs bound by IGF2BP1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 131,
      "y" : 85
    },
    "minX" : 67,
    "maxX" : 196,
    "minY" : 54,
    "maxY" : 174,
    "prop" : {
      "x" : 67,
      "y" : 54,
      "width" : 129,
      "height" : 63
    },
    "textPosition" : {
      "x" : 78,
      "y" : 68
    },
    "connectors" : [ {
      "edgeId" : 2,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 152,
          "y" : 123
        },
        "to" : {
          "x" : 192,
          "y" : 174
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 4,
    "reactomeId" : 428366,
    "displayName" : "IGF2BP1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 282,
      "y" : 85
    },
    "minX" : 192,
    "maxX" : 353,
    "minY" : 48,
    "maxY" : 174,
    "prop" : {
      "x" : 218,
      "y" : 54,
      "width" : 129,
      "height" : 63
    },
    "textPosition" : {
      "x" : 253,
      "y" : 75
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 347,
          "y" : 54
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 347,
          "y" : 54
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 250,
          "y" : 120
        },
        "to" : {
          "x" : 192,
          "y" : 174
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 5,
    "reactomeId" : 428327,
    "displayName" : "IGF2BP1:RNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 194,
      "y" : 341
    },
    "minX" : 132,
    "maxX" : 263,
    "minY" : 318,
    "maxY" : 359,
    "prop" : {
      "x" : 132,
      "y" : 324,
      "width" : 125,
      "height" : 35
    },
    "textPosition" : {
      "x" : 150,
      "y" : 338
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 257,
          "y" : 324
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 257,
          "y" : 324
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 7,
    "reactomeId" : 428302,
    "displayName" : "IGF2BP2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 596,
      "y" : 86
    },
    "minX" : 508,
    "maxX" : 667,
    "minY" : 49,
    "maxY" : 176,
    "prop" : {
      "x" : 532,
      "y" : 55,
      "width" : 129,
      "height" : 63
    },
    "textPosition" : {
      "x" : 567,
      "y" : 76
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 661,
          "y" : 55
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 661,
          "y" : 55
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 6,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 565,
          "y" : 121
        },
        "to" : {
          "x" : 508,
          "y" : 176
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 8,
    "reactomeId" : 428328,
    "displayName" : "RNAs bound by IGF2BP2",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 442,
      "y" : 88
    },
    "minX" : 378,
    "maxX" : 508,
    "minY" : 57,
    "maxY" : 176,
    "prop" : {
      "x" : 378,
      "y" : 57,
      "width" : 129,
      "height" : 63
    },
    "textPosition" : {
      "x" : 389,
      "y" : 71
    },
    "connectors" : [ {
      "edgeId" : 6,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 465,
          "y" : 126
        },
        "to" : {
          "x" : 508,
          "y" : 176
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 9,
    "reactomeId" : 428335,
    "displayName" : "IGF2BP2:RNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 505,
      "y" : 345
    },
    "minX" : 443,
    "maxX" : 574,
    "minY" : 322,
    "maxY" : 363,
    "prop" : {
      "x" : 443,
      "y" : 328,
      "width" : 125,
      "height" : 35
    },
    "textPosition" : {
      "x" : 461,
      "y" : 342
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 568,
          "y" : 328
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 568,
          "y" : 328
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 6,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 11,
    "reactomeId" : 428313,
    "displayName" : "IGF2BP3",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 930,
      "y" : 87
    },
    "minX" : 860,
    "maxX" : 1001,
    "minY" : 50,
    "maxY" : 169,
    "prop" : {
      "x" : 866,
      "y" : 56,
      "width" : 129,
      "height" : 63
    },
    "textPosition" : {
      "x" : 901,
      "y" : 77
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 995,
          "y" : 56
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 995,
          "y" : 56
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 10,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 903,
          "y" : 122
        },
        "to" : {
          "x" : 860,
          "y" : 169
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 12,
    "reactomeId" : 428384,
    "displayName" : "RNAs bound by IGF2BP3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 762,
      "y" : 89
    },
    "minX" : 698,
    "maxX" : 860,
    "minY" : 58,
    "maxY" : 169,
    "prop" : {
      "x" : 698,
      "y" : 58,
      "width" : 129,
      "height" : 63
    },
    "textPosition" : {
      "x" : 709,
      "y" : 72
    },
    "connectors" : [ {
      "edgeId" : 10,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 800,
          "y" : 127
        },
        "to" : {
          "x" : 860,
          "y" : 169
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 13,
    "reactomeId" : 428310,
    "displayName" : "IGF2BP3:RNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 865,
      "y" : 344
    },
    "minX" : 803,
    "maxX" : 934,
    "minY" : 321,
    "maxY" : 362,
    "prop" : {
      "x" : 803,
      "y" : 327,
      "width" : 125,
      "height" : 35
    },
    "textPosition" : {
      "x" : 821,
      "y" : 341
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 928,
          "y" : 327
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 928,
          "y" : 327
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 10,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 2,
    "reactomeId" : 428296,
    "displayName" : "IGF2BP1 binds specific RNAs",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 192,
      "y" : 244
    },
    "minX" : 187,
    "maxX" : 197,
    "minY" : 174,
    "maxY" : 321,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 192,
        "y" : 174
      },
      "to" : {
        "x" : 192,
        "y" : 244
      }
    }, {
      "from" : {
        "x" : 192,
        "y" : 244
      },
      "to" : {
        "x" : 193,
        "y" : 321
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 189,
        "y" : 314
      },
      "b" : {
        "x" : 193,
        "y" : 321
      },
      "c" : {
        "x" : 197,
        "y" : 314
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 197,
        "y" : 314
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 192,
        "y" : 244
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 192,
        "y" : 244
      }
    },
    "inputs" : [ {
      "id" : 3,
      "points" : [ {
        "x" : 152,
        "y" : 123
      } ]
    }, {
      "id" : 4,
      "points" : [ {
        "x" : 250,
        "y" : 120
      } ]
    } ],
    "outputs" : [ {
      "id" : 5
    } ]
  }, {
    "id" : 6,
    "reactomeId" : 428293,
    "displayName" : "IGF2BP2 binds specific RNAs",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 505,
      "y" : 246
    },
    "minX" : 500,
    "maxX" : 510,
    "minY" : 176,
    "maxY" : 325,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 508,
        "y" : 176
      },
      "to" : {
        "x" : 505,
        "y" : 246
      }
    }, {
      "from" : {
        "x" : 505,
        "y" : 246
      },
      "to" : {
        "x" : 505,
        "y" : 325
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 501,
        "y" : 318
      },
      "b" : {
        "x" : 505,
        "y" : 325
      },
      "c" : {
        "x" : 509,
        "y" : 318
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 509,
        "y" : 318
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 505,
        "y" : 246
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 505,
        "y" : 246
      }
    },
    "inputs" : [ {
      "id" : 7,
      "points" : [ {
        "x" : 565,
        "y" : 121
      } ]
    }, {
      "id" : 8,
      "points" : [ {
        "x" : 465,
        "y" : 126
      } ]
    } ],
    "outputs" : [ {
      "id" : 9
    } ]
  }, {
    "id" : 10,
    "reactomeId" : 428287,
    "displayName" : "IGF2BP3 binds specific RNAs",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 863,
      "y" : 247
    },
    "minX" : 858,
    "maxX" : 868,
    "minY" : 169,
    "maxY" : 324,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 860,
        "y" : 169
      },
      "to" : {
        "x" : 863,
        "y" : 247
      }
    }, {
      "from" : {
        "x" : 863,
        "y" : 247
      },
      "to" : {
        "x" : 864,
        "y" : 324
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 860,
        "y" : 317
      },
      "b" : {
        "x" : 864,
        "y" : 324
      },
      "c" : {
        "x" : 868,
        "y" : 317
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 868,
        "y" : 317
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 863,
        "y" : 247
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 863,
        "y" : 247
      }
    },
    "inputs" : [ {
      "id" : 11,
      "points" : [ {
        "x" : 903,
        "y" : 122
      } ]
    }, {
      "id" : 12,
      "points" : [ {
        "x" : 800,
        "y" : 127
      } ]
    } ],
    "outputs" : [ {
      "id" : 13
    } ]
  } ],
  "compartments" : [ {
    "id" : 1,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 535,
      "y" : 208
    },
    "minX" : 0,
    "maxX" : 1070,
    "minY" : 0,
    "maxY" : 417,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 1070,
      "height" : 417
    },
    "textPosition" : {
      "x" : 34,
      "y" : 381
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 1050,
      "height" : 397
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 1070,
  "minY" : 0,
  "maxY" : 417,
  "disease" : false
}