{
  "dbId" : 373753,
  "stableId" : "R-HSA-373753",
  "displayName" : "Nephrin family interactions",
  "nodes" : [ {
    "id" : 3,
    "reactomeId" : 373670,
    "displayName" : "NPHS1 dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 424,
      "y" : 38
    },
    "minX" : 174,
    "maxX" : 560,
    "minY" : 6,
    "maxY" : 75,
    "prop" : {
      "x" : 378,
      "y" : 27,
      "width" : 92,
      "height" : 22
    },
    "textPosition" : {
      "x" : 379,
      "y" : 28
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 470,
          "y" : 27
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 470,
          "y" : 27
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 1,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 4,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 473,
          "y" : 27
        },
        "to" : {
          "x" : 560,
          "y" : 6
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 7,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 375,
          "y" : 44
        },
        "to" : {
          "x" : 174,
          "y" : 75
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 6,
    "reactomeId" : 373679,
    "displayName" : "NPHS1 dimer:KIRREL",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 663,
      "y" : 36
    },
    "minX" : 177,
    "maxX" : 717,
    "minY" : 12,
    "maxY" : 476,
    "prop" : {
      "x" : 615,
      "y" : 18,
      "width" : 96,
      "height" : 36
    },
    "textPosition" : {
      "x" : 616,
      "y" : 19
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 711,
          "y" : 18
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 711,
          "y" : 18
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 35,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 632,
          "y" : 57
        },
        "to" : {
          "x" : 182,
          "y" : 319
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 4,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 38,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 638,
          "y" : 57
        },
        "to" : {
          "x" : 177,
          "y" : 394
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 42,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 644,
          "y" : 57
        },
        "to" : {
          "x" : 210,
          "y" : 476
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 428,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 681,
          "y" : 57
        },
        "to" : {
          "x" : 712,
          "y" : 84
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 9,
    "reactomeId" : 451719,
    "displayName" : "NPHS1 dimer:KIRREL2,KIRREL3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 50,
      "y" : 70
    },
    "minX" : 2,
    "maxX" : 105,
    "minY" : 39,
    "maxY" : 95,
    "prop" : {
      "x" : 2,
      "y" : 45,
      "width" : 97,
      "height" : 50
    },
    "textPosition" : {
      "x" : 4,
      "y" : 46
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 99,
          "y" : 45
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 99,
          "y" : 45
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 7,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 397,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 796,
      "y" : 123
    },
    "minX" : 776,
    "maxX" : 817,
    "minY" : 72,
    "maxY" : 138,
    "prop" : {
      "x" : 776,
      "y" : 108,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 780,
      "y" : 112
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 811,
          "y" : 113
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 811,
          "y" : 113
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 13,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 801,
          "y" : 105
        },
        "to" : {
          "x" : 815,
          "y" : 72
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 802,
            "y" : 82
          },
          "b" : {
            "x" : 814,
            "y" : 94
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 808,
            "y" : 88
          }
        }
      }
    } ]
  }, {
    "id" : 14,
    "reactomeId" : 200917,
    "displayName" : "FYN",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 692,
      "y" : 122
    },
    "minX" : 677,
    "maxX" : 713,
    "minY" : 84,
    "maxY" : 133,
    "prop" : {
      "x" : 677,
      "y" : 111,
      "width" : 30,
      "height" : 22
    },
    "textPosition" : {
      "x" : 681,
      "y" : 105
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 707,
          "y" : 111
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 707,
          "y" : 111
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 428,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 697,
          "y" : 108
        },
        "to" : {
          "x" : 712,
          "y" : 84
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 16,
    "reactomeId" : 374555,
    "displayName" : "p-Y1158,Y1176,Y1193,Y1217-NPHS1:KIRREL:FYN",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 945,
      "y" : 43
    },
    "minX" : 861,
    "maxX" : 1187,
    "minY" : 11,
    "maxY" : 243,
    "prop" : {
      "x" : 885,
      "y" : 17,
      "width" : 121,
      "height" : 53
    },
    "textPosition" : {
      "x" : 885,
      "y" : 21
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1006,
          "y" : 17
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1006,
          "y" : 17
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 13,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 882,
          "y" : 63
        },
        "to" : {
          "x" : 861,
          "y" : 72
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 877,
          "y" : 69
        },
        "b" : {
          "x" : 882,
          "y" : 63
        },
        "c" : {
          "x" : 874,
          "y" : 62
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 874,
          "y" : 62
        }
      }
    }, {
      "edgeId" : 19,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1009,
          "y" : 44
        },
        "to" : {
          "x" : 1099,
          "y" : 48
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 25,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 984,
          "y" : 73
        },
        "to" : {
          "x" : 1187,
          "y" : 204
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 29,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 967,
          "y" : 73
        },
        "to" : {
          "x" : 1114,
          "y" : 243
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 17,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 903,
      "y" : 122
    },
    "minX" : 861,
    "maxX" : 924,
    "minY" : 72,
    "maxY" : 137,
    "prop" : {
      "x" : 883,
      "y" : 107,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 886,
      "y" : 111
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 918,
          "y" : 112
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 918,
          "y" : 112
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 13,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 890,
          "y" : 104
        },
        "to" : {
          "x" : 861,
          "y" : 72
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 869,
            "y" : 82
          },
          "b" : {
            "x" : 881,
            "y" : 94
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 875,
            "y" : 88
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 882,
          "y" : 102
        },
        "b" : {
          "x" : 890,
          "y" : 104
        },
        "c" : {
          "x" : 888,
          "y" : 96
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 888,
          "y" : 96
        }
      }
    } ]
  }, {
    "id" : 20,
    "reactomeId" : 381949,
    "displayName" : "NCK1,NCK2",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1077,
      "y" : 76
    },
    "minX" : 1032,
    "maxX" : 1123,
    "minY" : 48,
    "maxY" : 87,
    "prop" : {
      "x" : 1032,
      "y" : 65,
      "width" : 91,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1039,
      "y" : 65
    },
    "connectors" : [ {
      "edgeId" : 19,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1085,
          "y" : 59
        },
        "to" : {
          "x" : 1099,
          "y" : 48
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 21,
    "reactomeId" : 373677,
    "displayName" : "NEPH1:p-Nephrin:Fyn:NCK",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1251,
      "y" : 39
    },
    "minX" : 1193,
    "maxX" : 1316,
    "minY" : 15,
    "maxY" : 80,
    "prop" : {
      "x" : 1193,
      "y" : 21,
      "width" : 117,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1196,
      "y" : 22
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1310,
          "y" : 21
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1310,
          "y" : 21
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 22,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1234,
          "y" : 60
        },
        "to" : {
          "x" : 1213,
          "y" : 80
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 23,
    "reactomeId" : 201873,
    "displayName" : "N-WASP",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1169,
      "y" : 76
    },
    "minX" : 1142,
    "maxX" : 1213,
    "minY" : 59,
    "maxY" : 87,
    "prop" : {
      "x" : 1142,
      "y" : 65,
      "width" : 55,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1148,
      "y" : 59
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1197,
          "y" : 65
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1197,
          "y" : 65
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 22,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1200,
          "y" : 78
        },
        "to" : {
          "x" : 1213,
          "y" : 80
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 24,
    "reactomeId" : 532605,
    "displayName" : "NEPH1:p-Nephrin:Fyn:NCK:N-WASP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1278,
      "y" : 137
    },
    "minX" : 1220,
    "maxX" : 1343,
    "minY" : 113,
    "maxY" : 155,
    "prop" : {
      "x" : 1220,
      "y" : 119,
      "width" : 117,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1221,
      "y" : 106
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1337,
          "y" : 119
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1337,
          "y" : 119
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 22,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26,
    "reactomeId" : 451771,
    "displayName" : "Podocin oligomer",
    "schemaClass" : "Polymer",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1275,
      "y" : 187
    },
    "minX" : 1187,
    "maxX" : 1329,
    "minY" : 176,
    "maxY" : 204,
    "prop" : {
      "x" : 1222,
      "y" : 176,
      "width" : 107,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1244,
      "y" : 170
    },
    "connectors" : [ {
      "edgeId" : 25,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1219,
          "y" : 197
        },
        "to" : {
          "x" : 1187,
          "y" : 204
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 27,
    "reactomeId" : 373691,
    "displayName" : "Podocin:p-Nephrin:Fyn:NEPH1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1277,
      "y" : 279
    },
    "minX" : 1216,
    "maxX" : 1344,
    "minY" : 255,
    "maxY" : 297,
    "prop" : {
      "x" : 1216,
      "y" : 261,
      "width" : 122,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1234,
      "y" : 248
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1338,
          "y" : 261
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1338,
          "y" : 261
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 25,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 30,
    "reactomeId" : 373620,
    "displayName" : "CD2AP",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1053,
      "y" : 235
    },
    "minX" : 1029,
    "maxX" : 1114,
    "minY" : 218,
    "maxY" : 246,
    "prop" : {
      "x" : 1029,
      "y" : 224,
      "width" : 48,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1032,
      "y" : 218
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1077,
          "y" : 224
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1077,
          "y" : 224
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 29,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1080,
          "y" : 238
        },
        "to" : {
          "x" : 1114,
          "y" : 243
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 31,
    "reactomeId" : 373680,
    "displayName" : "CD2AP:p-Nephrin:Fyn:NEPH1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1276,
      "y" : 370
    },
    "minX" : 1218,
    "maxX" : 1341,
    "minY" : 346,
    "maxY" : 424,
    "prop" : {
      "x" : 1218,
      "y" : 352,
      "width" : 117,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1233,
      "y" : 339
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1335,
          "y" : 352
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1335,
          "y" : 352
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 32,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1266,
          "y" : 391
        },
        "to" : {
          "x" : 1246,
          "y" : 424
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 29,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 33,
    "reactomeId" : 74693,
    "displayName" : "PI3K",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1171,
      "y" : 379
    },
    "minX" : 1154,
    "maxX" : 1246,
    "minY" : 362,
    "maxY" : 424,
    "prop" : {
      "x" : 1154,
      "y" : 368,
      "width" : 34,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1154,
      "y" : 369
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1188,
          "y" : 368
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1188,
          "y" : 368
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 32,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1191,
          "y" : 389
        },
        "to" : {
          "x" : 1246,
          "y" : 424
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 34,
    "reactomeId" : 451720,
    "displayName" : "PI3K:CD2AP:p-Nephrin:Fyn:NEPH1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1275,
      "y" : 498
    },
    "minX" : 1215,
    "maxX" : 1342,
    "minY" : 474,
    "maxY" : 516,
    "prop" : {
      "x" : 1215,
      "y" : 480,
      "width" : 121,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1228,
      "y" : 467
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1336,
          "y" : 480
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1336,
          "y" : 480
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 32,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 36,
    "reactomeId" : 373631,
    "displayName" : "CASK",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 185,
      "y" : 346
    },
    "minX" : 166,
    "maxX" : 210,
    "minY" : 319,
    "maxY" : 357,
    "prop" : {
      "x" : 166,
      "y" : 335,
      "width" : 38,
      "height" : 22
    },
    "textPosition" : {
      "x" : 169,
      "y" : 329
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 204,
          "y" : 335
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 204,
          "y" : 335
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 35,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 183,
          "y" : 332
        },
        "to" : {
          "x" : 182,
          "y" : 319
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 37,
    "reactomeId" : 373681,
    "displayName" : "Nephrin dimer:CASK",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 63,
      "y" : 321
    },
    "minX" : 0,
    "maxX" : 132,
    "minY" : 304,
    "maxY" : 332,
    "prop" : {
      "x" : 0,
      "y" : 310,
      "width" : 126,
      "height" : 22
    },
    "textPosition" : {
      "x" : 13,
      "y" : 297
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 126,
          "y" : 310
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 126,
          "y" : 310
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 35,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 39,
    "reactomeId" : 381681,
    "displayName" : "IQGAP1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 183,
      "y" : 421
    },
    "minX" : 157,
    "maxX" : 215,
    "minY" : 394,
    "maxY" : 432,
    "prop" : {
      "x" : 157,
      "y" : 410,
      "width" : 52,
      "height" : 22
    },
    "textPosition" : {
      "x" : 160,
      "y" : 404
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 209,
          "y" : 410
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 209,
          "y" : 410
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 38,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 180,
          "y" : 407
        },
        "to" : {
          "x" : 177,
          "y" : 394
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 40,
    "reactomeId" : 451398,
    "displayName" : "Nephrin dimer:IQGAP1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 61,
      "y" : 395
    },
    "minX" : 13,
    "maxX" : 115,
    "minY" : 371,
    "maxY" : 413,
    "prop" : {
      "x" : 13,
      "y" : 377,
      "width" : 96,
      "height" : 36
    },
    "textPosition" : {
      "x" : 15,
      "y" : 378
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 109,
          "y" : 377
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 109,
          "y" : 377
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 38,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 43,
    "reactomeId" : 451386,
    "displayName" : "adherens junction-associated proteins",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 234,
      "y" : 517
    },
    "minX" : 174,
    "maxX" : 294,
    "minY" : 476,
    "maxY" : 535,
    "prop" : {
      "x" : 174,
      "y" : 499,
      "width" : 120,
      "height" : 36
    },
    "textPosition" : {
      "x" : 193,
      "y" : 486
    },
    "connectors" : [ {
      "edgeId" : 42,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 223,
          "y" : 493
        },
        "to" : {
          "x" : 210,
          "y" : 476
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 44,
    "reactomeId" : 451387,
    "displayName" : "Nephrin dimer:adherins junction-associated proteins",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 66,
      "y" : 480
    },
    "minX" : 6,
    "maxX" : 132,
    "minY" : 449,
    "maxY" : 505,
    "prop" : {
      "x" : 6,
      "y" : 455,
      "width" : 120,
      "height" : 50
    },
    "textPosition" : {
      "x" : 16,
      "y" : 428
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 126,
          "y" : 455
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 126,
          "y" : 455
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 42,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 45,
    "reactomeId" : 936056,
    "displayName" : "KIRREL2, KIRREL3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 193,
      "y" : 36
    },
    "minX" : 155,
    "maxX" : 231,
    "minY" : 21,
    "maxY" : 75,
    "prop" : {
      "x" : 155,
      "y" : 21,
      "width" : 76,
      "height" : 30
    },
    "textPosition" : {
      "x" : 161,
      "y" : 19
    },
    "connectors" : [ {
      "edgeId" : 7,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 185,
          "y" : 57
        },
        "to" : {
          "x" : 174,
          "y" : 75
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 47,
    "reactomeId" : 8981500,
    "displayName" : "NPHS1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 293,
      "y" : 34
    },
    "minX" : 269,
    "maxX" : 346,
    "minY" : 13,
    "maxY" : 45,
    "prop" : {
      "x" : 269,
      "y" : 23,
      "width" : 48,
      "height" : 22
    },
    "textPosition" : {
      "x" : 272,
      "y" : 17
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 317,
          "y" : 23
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 317,
          "y" : 23
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 1,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 334,
            "y" : 13
          },
          "b" : {
            "x" : 346,
            "y" : 25
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 340,
            "y" : 19
          }
        }
      }
    } ]
  }, {
    "id" : 48,
    "reactomeId" : 8954311,
    "displayName" : "KIRREL",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 554,
      "y" : 37
    },
    "minX" : 530,
    "maxX" : 585,
    "minY" : 6,
    "maxY" : 48,
    "prop" : {
      "x" : 530,
      "y" : 26,
      "width" : 49,
      "height" : 22
    },
    "textPosition" : {
      "x" : 530,
      "y" : 26
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 579,
          "y" : 26
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 579,
          "y" : 26
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 4,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 556,
          "y" : 23
        },
        "to" : {
          "x" : 560,
          "y" : 6
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 379,
    "reactomeId" : 8981533,
    "displayName" : "NPHS1 dimer:KIRREL:FYN",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 767,
      "y" : 37
    },
    "minX" : 722,
    "maxX" : 844,
    "minY" : 13,
    "maxY" : 72,
    "prop" : {
      "x" : 722,
      "y" : 19,
      "width" : 90,
      "height" : 36
    },
    "textPosition" : {
      "x" : 729,
      "y" : 6
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 812,
          "y" : 19
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 812,
          "y" : 19
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 428,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 13,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 791,
          "y" : 58
        },
        "to" : {
          "x" : 815,
          "y" : 72
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 13,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 815,
          "y" : 35
        },
        "to" : {
          "x" : 839,
          "y" : 34
        }
      }, {
        "from" : {
          "x" : 839,
          "y" : 34
        },
        "to" : {
          "x" : 840,
          "y" : 55
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 840,
          "y" : 59
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 840,
          "y" : 59
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 32,
    "reactomeId" : 451758,
    "displayName" : "p85 associates with both p-Nephrin and CD2AP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1246,
      "y" : 453
    },
    "minX" : 1241,
    "maxX" : 1263,
    "minY" : 424,
    "maxY" : 477,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1246,
        "y" : 424
      },
      "to" : {
        "x" : 1246,
        "y" : 453
      }
    }, {
      "from" : {
        "x" : 1246,
        "y" : 453
      },
      "to" : {
        "x" : 1263,
        "y" : 477
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1256,
        "y" : 474
      },
      "b" : {
        "x" : 1263,
        "y" : 477
      },
      "c" : {
        "x" : 1262,
        "y" : 469
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1262,
        "y" : 469
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1246,
        "y" : 453
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1246,
        "y" : 453
      }
    },
    "inputs" : [ {
      "id" : 33,
      "points" : [ {
        "x" : 1191,
        "y" : 389
      } ]
    }, {
      "id" : 31,
      "points" : [ {
        "x" : 1266,
        "y" : 391
      } ]
    } ],
    "outputs" : [ {
      "id" : 34
    } ]
  }, {
    "id" : 1,
    "reactomeId" : 373732,
    "displayName" : "Nephrin trans-homophilic interaction",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 361,
      "y" : 13
    },
    "minX" : 320,
    "maxX" : 396,
    "minY" : 8,
    "maxY" : 26,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 320,
        "y" : 26
      },
      "to" : {
        "x" : 361,
        "y" : 13
      }
    }, {
      "from" : {
        "x" : 361,
        "y" : 13
      },
      "to" : {
        "x" : 396,
        "y" : 24
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 388,
        "y" : 26
      },
      "b" : {
        "x" : 396,
        "y" : 24
      },
      "c" : {
        "x" : 391,
        "y" : 18
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 391,
        "y" : 18
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 361,
        "y" : 13
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 361,
        "y" : 13
      }
    },
    "inputs" : [ {
      "id" : 47,
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 3
    } ]
  }, {
    "id" : 35,
    "reactomeId" : 373722,
    "displayName" : "Nephrin binds CASK",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 152,
      "y" : 318
    },
    "minX" : 129,
    "maxX" : 182,
    "minY" : 313,
    "maxY" : 323,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 182,
        "y" : 319
      },
      "to" : {
        "x" : 152,
        "y" : 318
      }
    }, {
      "from" : {
        "x" : 152,
        "y" : 318
      },
      "to" : {
        "x" : 129,
        "y" : 318
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 136,
        "y" : 314
      },
      "b" : {
        "x" : 129,
        "y" : 318
      },
      "c" : {
        "x" : 136,
        "y" : 322
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 136,
        "y" : 322
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 152,
        "y" : 318
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 152,
        "y" : 318
      }
    },
    "inputs" : [ {
      "id" : 36,
      "points" : [ {
        "x" : 183,
        "y" : 332
      } ]
    }, {
      "id" : 6,
      "points" : [ {
        "x" : 632,
        "y" : 57
      } ]
    } ],
    "outputs" : [ {
      "id" : 37
    } ]
  }, {
    "id" : 4,
    "reactomeId" : 373714,
    "displayName" : "Cis-Heterodimerization of nephrin and KIRREL",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 583,
      "y" : 5
    },
    "minX" : 560,
    "maxX" : 616,
    "minY" : 0,
    "maxY" : 15,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 560,
        "y" : 6
      },
      "to" : {
        "x" : 583,
        "y" : 5
      }
    }, {
      "from" : {
        "x" : 583,
        "y" : 5
      },
      "to" : {
        "x" : 616,
        "y" : 15
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 608,
        "y" : 17
      },
      "b" : {
        "x" : 616,
        "y" : 15
      },
      "c" : {
        "x" : 611,
        "y" : 9
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 611,
        "y" : 9
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 583,
        "y" : 5
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 583,
        "y" : 5
      }
    },
    "inputs" : [ {
      "id" : 3,
      "points" : [ {
        "x" : 473,
        "y" : 27
      } ]
    }, {
      "id" : 48,
      "points" : [ {
        "x" : 556,
        "y" : 23
      } ]
    } ],
    "outputs" : [ {
      "id" : 6
    } ]
  }, {
    "id" : 38,
    "reactomeId" : 451377,
    "displayName" : "Interaction of IQGAP1 with nephrin",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 141,
      "y" : 394
    },
    "minX" : 112,
    "maxX" : 177,
    "minY" : 389,
    "maxY" : 399,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 177,
        "y" : 394
      },
      "to" : {
        "x" : 141,
        "y" : 394
      }
    }, {
      "from" : {
        "x" : 141,
        "y" : 394
      },
      "to" : {
        "x" : 112,
        "y" : 394
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 119,
        "y" : 390
      },
      "b" : {
        "x" : 112,
        "y" : 394
      },
      "c" : {
        "x" : 119,
        "y" : 398
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 119,
        "y" : 398
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 141,
        "y" : 394
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 141,
        "y" : 394
      }
    },
    "inputs" : [ {
      "id" : 39,
      "points" : [ {
        "x" : 180,
        "y" : 407
      } ]
    }, {
      "id" : 6,
      "points" : [ {
        "x" : 638,
        "y" : 57
      } ]
    } ],
    "outputs" : [ {
      "id" : 40
    } ]
  }, {
    "id" : 7,
    "reactomeId" : 451757,
    "displayName" : "Heterodimerization of nephrin and KIRREL2, KIRREL3",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 134,
      "y" : 76
    },
    "minX" : 102,
    "maxX" : 174,
    "minY" : 71,
    "maxY" : 81,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 174,
        "y" : 75
      },
      "to" : {
        "x" : 134,
        "y" : 76
      }
    }, {
      "from" : {
        "x" : 134,
        "y" : 76
      },
      "to" : {
        "x" : 102,
        "y" : 73
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 109,
        "y" : 70
      },
      "b" : {
        "x" : 102,
        "y" : 73
      },
      "c" : {
        "x" : 109,
        "y" : 78
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 109,
        "y" : 78
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 134,
        "y" : 76
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 134,
        "y" : 76
      }
    },
    "inputs" : [ {
      "id" : 45,
      "points" : [ {
        "x" : 185,
        "y" : 57
      } ]
    }, {
      "id" : 3,
      "points" : [ {
        "x" : 375,
        "y" : 44
      } ]
    } ],
    "outputs" : [ {
      "id" : 9
    } ]
  }, {
    "id" : 42,
    "reactomeId" : 451403,
    "displayName" : "Interaction of nephrin with adherens junction-associated proteins",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 179,
      "y" : 477
    },
    "minX" : 129,
    "maxX" : 210,
    "minY" : 472,
    "maxY" : 482,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 210,
        "y" : 476
      },
      "to" : {
        "x" : 179,
        "y" : 477
      }
    }, {
      "from" : {
        "x" : 179,
        "y" : 477
      },
      "to" : {
        "x" : 129,
        "y" : 478
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 136,
        "y" : 474
      },
      "b" : {
        "x" : 129,
        "y" : 478
      },
      "c" : {
        "x" : 136,
        "y" : 482
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 136,
        "y" : 482
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 179,
        "y" : 477
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 179,
        "y" : 477
      }
    },
    "inputs" : [ {
      "id" : 43,
      "points" : [ {
        "x" : 223,
        "y" : 493
      } ]
    }, {
      "id" : 6,
      "points" : [ {
        "x" : 644,
        "y" : 57
      } ]
    } ],
    "outputs" : [ {
      "id" : 44
    } ]
  }, {
    "id" : 428,
    "reactomeId" : 8981534,
    "displayName" : "Nephrin dimer:KIRREL binds FYN",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 734,
      "y" : 84
    },
    "minX" : 712,
    "maxX" : 754,
    "minY" : 58,
    "maxY" : 89,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 712,
        "y" : 84
      },
      "to" : {
        "x" : 734,
        "y" : 84
      }
    }, {
      "from" : {
        "x" : 734,
        "y" : 84
      },
      "to" : {
        "x" : 754,
        "y" : 58
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 753,
        "y" : 66
      },
      "b" : {
        "x" : 754,
        "y" : 58
      },
      "c" : {
        "x" : 747,
        "y" : 61
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 747,
        "y" : 61
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 734,
        "y" : 84
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 734,
        "y" : 84
      }
    },
    "inputs" : [ {
      "id" : 6,
      "points" : [ {
        "x" : 681,
        "y" : 57
      } ]
    }, {
      "id" : 14,
      "points" : [ {
        "x" : 697,
        "y" : 108
      } ]
    } ],
    "outputs" : [ {
      "id" : 379
    } ]
  }, {
    "id" : 13,
    "reactomeId" : 373747,
    "displayName" : "Phosphorylation of nephrin by FYN",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 840,
      "y" : 71
    },
    "minX" : 815,
    "maxX" : 861,
    "minY" : 65,
    "maxY" : 77,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 815,
        "y" : 72
      },
      "to" : {
        "x" : 840,
        "y" : 71
      }
    }, {
      "from" : {
        "x" : 840,
        "y" : 71
      },
      "to" : {
        "x" : 861,
        "y" : 72
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 834,
        "y" : 65
      },
      "b" : {
        "x" : 846,
        "y" : 77
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 840,
        "y" : 71
      }
    },
    "inputs" : [ {
      "id" : 397,
      "points" : [ {
        "x" : 801,
        "y" : 105
      } ],
      "stoichiometry" : 4
    }, {
      "id" : 379,
      "points" : [ {
        "x" : 791,
        "y" : 58
      } ]
    } ],
    "outputs" : [ {
      "id" : 16,
      "points" : [ {
        "x" : 882,
        "y" : 63
      } ]
    }, {
      "id" : 17,
      "points" : [ {
        "x" : 890,
        "y" : 104
      } ],
      "stoichiometry" : 4
    } ],
    "catalysts" : [ {
      "id" : 379,
      "points" : [ {
        "x" : 815,
        "y" : 35
      }, {
        "x" : 839,
        "y" : 34
      } ]
    } ]
  }, {
    "id" : 19,
    "reactomeId" : 373724,
    "displayName" : "Nephrin binds NCK",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1127,
      "y" : 48
    },
    "minX" : 1099,
    "maxX" : 1190,
    "minY" : 43,
    "maxY" : 53,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1099,
        "y" : 48
      },
      "to" : {
        "x" : 1127,
        "y" : 48
      }
    }, {
      "from" : {
        "x" : 1127,
        "y" : 48
      },
      "to" : {
        "x" : 1190,
        "y" : 43
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1183,
        "y" : 48
      },
      "b" : {
        "x" : 1190,
        "y" : 43
      },
      "c" : {
        "x" : 1183,
        "y" : 40
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1183,
        "y" : 40
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1127,
        "y" : 48
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1127,
        "y" : 48
      }
    },
    "inputs" : [ {
      "id" : 16,
      "points" : [ {
        "x" : 1009,
        "y" : 44
      } ]
    }, {
      "id" : 20,
      "points" : [ {
        "x" : 1085,
        "y" : 59
      } ]
    } ],
    "outputs" : [ {
      "id" : 21
    } ]
  }, {
    "id" : 22,
    "reactomeId" : 532603,
    "displayName" : "Nephrin mediated activation of N-WASP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1221,
      "y" : 98
    },
    "minX" : 1213,
    "maxX" : 1251,
    "minY" : 80,
    "maxY" : 116,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1213,
        "y" : 80
      },
      "to" : {
        "x" : 1221,
        "y" : 98
      }
    }, {
      "from" : {
        "x" : 1221,
        "y" : 98
      },
      "to" : {
        "x" : 1251,
        "y" : 116
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1243,
        "y" : 116
      },
      "b" : {
        "x" : 1251,
        "y" : 116
      },
      "c" : {
        "x" : 1247,
        "y" : 109
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1247,
        "y" : 109
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1221,
        "y" : 98
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1221,
        "y" : 98
      }
    },
    "inputs" : [ {
      "id" : 21,
      "points" : [ {
        "x" : 1234,
        "y" : 60
      } ]
    }, {
      "id" : 23,
      "points" : [ {
        "x" : 1200,
        "y" : 78
      } ]
    } ],
    "outputs" : [ {
      "id" : 24
    } ]
  }, {
    "id" : 25,
    "reactomeId" : 373734,
    "displayName" : "Nephrin interacts with Podocin",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1191,
      "y" : 236
    },
    "minX" : 1186,
    "maxX" : 1241,
    "minY" : 204,
    "maxY" : 258,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1187,
        "y" : 204
      },
      "to" : {
        "x" : 1191,
        "y" : 236
      }
    }, {
      "from" : {
        "x" : 1191,
        "y" : 236
      },
      "to" : {
        "x" : 1241,
        "y" : 258
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1233,
        "y" : 259
      },
      "b" : {
        "x" : 1241,
        "y" : 258
      },
      "c" : {
        "x" : 1236,
        "y" : 252
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1236,
        "y" : 252
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1191,
        "y" : 236
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1191,
        "y" : 236
      }
    },
    "inputs" : [ {
      "id" : 26,
      "points" : [ {
        "x" : 1219,
        "y" : 197
      } ]
    }, {
      "id" : 16,
      "points" : [ {
        "x" : 984,
        "y" : 73
      } ]
    } ],
    "outputs" : [ {
      "id" : 27
    } ]
  }, {
    "id" : 29,
    "reactomeId" : 373727,
    "displayName" : "Nephrin binds CD2AP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1163,
      "y" : 288
    },
    "minX" : 1114,
    "maxX" : 1251,
    "minY" : 243,
    "maxY" : 349,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1114,
        "y" : 243
      },
      "to" : {
        "x" : 1163,
        "y" : 288
      }
    }, {
      "from" : {
        "x" : 1163,
        "y" : 288
      },
      "to" : {
        "x" : 1251,
        "y" : 349
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1243,
        "y" : 348
      },
      "b" : {
        "x" : 1251,
        "y" : 349
      },
      "c" : {
        "x" : 1248,
        "y" : 342
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1248,
        "y" : 342
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1163,
        "y" : 288
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1163,
        "y" : 288
      }
    },
    "inputs" : [ {
      "id" : 16,
      "points" : [ {
        "x" : 967,
        "y" : 73
      } ]
    }, {
      "id" : 30,
      "points" : [ {
        "x" : 1080,
        "y" : 238
      } ]
    } ],
    "outputs" : [ {
      "id" : 31
    } ]
  } ],
  "compartments" : [ {
    "id" : 10,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 666,
      "y" : 293
    },
    "minX" : 54,
    "maxX" : 1279,
    "minY" : 30,
    "maxY" : 557,
    "prop" : {
      "x" : 54,
      "y" : 30,
      "width" : 1225,
      "height" : 527
    },
    "textPosition" : {
      "x" : 368,
      "y" : 495
    },
    "insets" : {
      "x" : 64,
      "y" : 39,
      "width" : 1208,
      "height" : 510
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 7, 9, 35, 37, 38, 40, 42, 44, 3, 6, 13, 14, 16, 17, 19, 20, 21, 22, 23, 24, 25, 26, 27, 29, 30, 31, 32, 33, 34, 36, 39, 43, 45, 48, 47, 379, 397, 428 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 1344,
  "minY" : 0,
  "maxY" : 557,
  "disease" : false
}