{
  "dbId" : 2408522,
  "stableId" : "R-HSA-2408522",
  "displayName" : "Selenoamino acid metabolism",
  "nodes" : [ {
    "id" : 260,
    "reactomeId" : 73532,
    "displayName" : "TNXRD1:FAD dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 980,
      "y" : 720
    },
    "minX" : 914,
    "maxX" : 1026,
    "minY" : 695,
    "maxY" : 740,
    "prop" : {
      "x" : 940,
      "y" : 701,
      "width" : 80,
      "height" : 39
    },
    "textPosition" : {
      "x" : 944,
      "y" : 705
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1020,
          "y" : 701
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1020,
          "y" : 701
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 250,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 937,
          "y" : 721
        },
        "to" : {
          "x" : 922,
          "y" : 721
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 918,
          "y" : 722
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 918,
          "y" : 722
        }
      }
    } ]
  }, {
    "id" : 5,
    "reactomeId" : 5357707,
    "displayName" : "SeMet",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 610,
      "y" : 196
    },
    "minX" : 440,
    "maxX" : 656,
    "minY" : 125,
    "maxY" : 244,
    "prop" : {
      "x" : 585,
      "y" : 181,
      "width" : 51,
      "height" : 30
    },
    "textPosition" : {
      "x" : 587,
      "y" : 185
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 631,
          "y" : 186
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 631,
          "y" : 186
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 4,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 626,
          "y" : 214
        },
        "to" : {
          "x" : 656,
          "y" : 239
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 12,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 582,
          "y" : 203
        },
        "to" : {
          "x" : 440,
          "y" : 244
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 312,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 610,
          "y" : 178
        },
        "to" : {
          "x" : 611,
          "y" : 125
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 262,
    "reactomeId" : 111745,
    "displayName" : "GSSG",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 753,
      "y" : 662
    },
    "minX" : 730,
    "maxX" : 821,
    "minY" : 646,
    "maxY" : 677,
    "prop" : {
      "x" : 730,
      "y" : 647,
      "width" : 47,
      "height" : 30
    },
    "textPosition" : {
      "x" : 732,
      "y" : 651
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 772,
          "y" : 652
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 772,
          "y" : 652
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 261,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 780,
          "y" : 663
        },
        "to" : {
          "x" : 821,
          "y" : 666
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 787,
          "y" : 660
        },
        "b" : {
          "x" : 780,
          "y" : 663
        },
        "c" : {
          "x" : 787,
          "y" : 667
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 787,
          "y" : 667
        }
      }
    } ]
  }, {
    "id" : 6,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 733,
      "y" : 204
    },
    "minX" : 656,
    "maxX" : 804,
    "minY" : 188,
    "maxY" : 239,
    "prop" : {
      "x" : 712,
      "y" : 189,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 716,
      "y" : 193
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 750,
          "y" : 194
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 750,
          "y" : 194
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 4,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 709,
          "y" : 213
        },
        "to" : {
          "x" : 656,
          "y" : 239
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 127,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 758,
          "y" : 213
        },
        "to" : {
          "x" : 804,
          "y" : 235
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 7,
    "reactomeId" : 936714,
    "displayName" : "2OBUTA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 550,
      "y" : 354
    },
    "minX" : 485,
    "maxX" : 656,
    "minY" : 318,
    "maxY" : 369,
    "prop" : {
      "x" : 485,
      "y" : 339,
      "width" : 130,
      "height" : 30
    },
    "textPosition" : {
      "x" : 521,
      "y" : 343
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 610,
          "y" : 344
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 610,
          "y" : 344
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 4,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 594,
          "y" : 336
        },
        "to" : {
          "x" : 656,
          "y" : 318
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 600,
          "y" : 330
        },
        "b" : {
          "x" : 594,
          "y" : 336
        },
        "c" : {
          "x" : 602,
          "y" : 338
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 602,
          "y" : 338
        }
      }
    } ]
  }, {
    "id" : 263,
    "reactomeId" : 29450,
    "displayName" : "GSH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 788,
      "y" : 765
    },
    "minX" : 768,
    "maxX" : 836,
    "minY" : 747,
    "maxY" : 780,
    "prop" : {
      "x" : 768,
      "y" : 750,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 771,
      "y" : 754
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 804,
          "y" : 755
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 804,
          "y" : 755
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 261,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 812,
          "y" : 757
        },
        "to" : {
          "x" : 836,
          "y" : 747
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 8,
    "reactomeId" : 5357669,
    "displayName" : "MeSeH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 728,
      "y" : 420
    },
    "minX" : 656,
    "maxX" : 975,
    "minY" : 314,
    "maxY" : 478,
    "prop" : {
      "x" : 700,
      "y" : 405,
      "width" : 56,
      "height" : 30
    },
    "textPosition" : {
      "x" : 702,
      "y" : 409
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 751,
          "y" : 410
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 751,
          "y" : 410
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 4,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 717,
          "y" : 402
        },
        "to" : {
          "x" : 656,
          "y" : 318
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 710,
          "y" : 399
        },
        "b" : {
          "x" : 717,
          "y" : 402
        },
        "c" : {
          "x" : 716,
          "y" : 394
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 716,
          "y" : 394
        }
      }
    }, {
      "edgeId" : 133,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 724,
          "y" : 438
        },
        "to" : {
          "x" : 716,
          "y" : 472
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 138,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 733,
          "y" : 438
        },
        "to" : {
          "x" : 751,
          "y" : 478
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 739,
          "y" : 443
        },
        "b" : {
          "x" : 733,
          "y" : 438
        },
        "c" : {
          "x" : 732,
          "y" : 446
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 732,
          "y" : 446
        }
      }
    }, {
      "edgeId" : 209,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 759,
          "y" : 419
        },
        "to" : {
          "x" : 975,
          "y" : 415
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 766,
          "y" : 415
        },
        "b" : {
          "x" : 759,
          "y" : 419
        },
        "c" : {
          "x" : 766,
          "y" : 423
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 766,
          "y" : 423
        }
      }
    }, {
      "edgeId" : 213,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 759,
          "y" : 427
        },
        "to" : {
          "x" : 911,
          "y" : 471
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 190,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 759,
          "y" : 414
        },
        "to" : {
          "x" : 871,
          "y" : 391
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 765,
          "y" : 409
        },
        "b" : {
          "x" : 759,
          "y" : 414
        },
        "c" : {
          "x" : 767,
          "y" : 417
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 767,
          "y" : 417
        }
      }
    }, {
      "edgeId" : 127,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 739,
          "y" : 402
        },
        "to" : {
          "x" : 807,
          "y" : 314
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 740,
          "y" : 394
        },
        "b" : {
          "x" : 739,
          "y" : 402
        },
        "c" : {
          "x" : 746,
          "y" : 399
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 746,
          "y" : 399
        }
      }
    } ]
  }, {
    "id" : 10,
    "reactomeId" : 1625212,
    "displayName" : "PXLP-K212-CTH tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 732,
      "y" : 278
    },
    "minX" : 664,
    "maxX" : 797,
    "minY" : 242,
    "maxY" : 309,
    "prop" : {
      "x" : 701,
      "y" : 248,
      "width" : 62,
      "height" : 61
    },
    "textPosition" : {
      "x" : 703,
      "y" : 232
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 763,
          "y" : 248
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 763,
          "y" : 248
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 4,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 698,
          "y" : 278
        },
        "to" : {
          "x" : 672,
          "y" : 279
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 668,
          "y" : 279
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 668,
          "y" : 279
        }
      }
    }, {
      "edgeId" : 127,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 766,
          "y" : 278
        },
        "to" : {
          "x" : 789,
          "y" : 278
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 793,
          "y" : 278
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 793,
          "y" : 278
        }
      }
    } ]
  }, {
    "id" : 268,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1263,
      "y" : 868
    },
    "minX" : 1232,
    "maxX" : 1286,
    "minY" : 802,
    "maxY" : 883,
    "prop" : {
      "x" : 1242,
      "y" : 853,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1246,
      "y" : 857
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1280,
          "y" : 858
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1280,
          "y" : 858
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 267,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1255,
          "y" : 850
        },
        "to" : {
          "x" : 1232,
          "y" : 802
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 1237,
            "y" : 820
          },
          "b" : {
            "x" : 1249,
            "y" : 832
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1243,
            "y" : 826
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1248,
          "y" : 845
        },
        "b" : {
          "x" : 1255,
          "y" : 850
        },
        "c" : {
          "x" : 1256,
          "y" : 842
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1256,
          "y" : 842
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 269,
    "reactomeId" : 5357667,
    "displayName" : "GSSeSG",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1316,
      "y" : 807
    },
    "minX" : 1232,
    "maxX" : 1417,
    "minY" : 791,
    "maxY" : 822,
    "prop" : {
      "x" : 1286,
      "y" : 792,
      "width" : 60,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1287,
      "y" : 796
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1341,
          "y" : 797
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1341,
          "y" : 797
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 267,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1283,
          "y" : 805
        },
        "to" : {
          "x" : 1232,
          "y" : 802
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1276,
          "y" : 809
        },
        "b" : {
          "x" : 1283,
          "y" : 805
        },
        "c" : {
          "x" : 1276,
          "y" : 801
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1276,
          "y" : 801
        }
      }
    }, {
      "edgeId" : 276,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1349,
          "y" : 806
        },
        "to" : {
          "x" : 1417,
          "y" : 806
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 13,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 339,
      "y" : 207
    },
    "minX" : 319,
    "maxX" : 440,
    "minY" : 191,
    "maxY" : 244,
    "prop" : {
      "x" : 319,
      "y" : 192,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 323,
      "y" : 196
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 354,
          "y" : 197
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 354,
          "y" : 197
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 12,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 362,
          "y" : 214
        },
        "to" : {
          "x" : 440,
          "y" : 244
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 14,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 443,
      "y" : 185
    },
    "minX" : 422,
    "maxX" : 466,
    "minY" : 169,
    "maxY" : 244,
    "prop" : {
      "x" : 422,
      "y" : 170,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 426,
      "y" : 174
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 460,
          "y" : 175
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 460,
          "y" : 175
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 12,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 442,
          "y" : 203
        },
        "to" : {
          "x" : 440,
          "y" : 244
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 15,
    "reactomeId" : 5357652,
    "displayName" : "AdoSeMet",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 341,
      "y" : 458
    },
    "minX" : 279,
    "maxX" : 443,
    "minY" : 402,
    "maxY" : 507,
    "prop" : {
      "x" : 304,
      "y" : 443,
      "width" : 74,
      "height" : 30
    },
    "textPosition" : {
      "x" : 305,
      "y" : 447
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 373,
          "y" : 448
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 373,
          "y" : 448
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 12,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 368,
          "y" : 440
        },
        "to" : {
          "x" : 443,
          "y" : 402
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 372,
          "y" : 433
        },
        "b" : {
          "x" : 368,
          "y" : 440
        },
        "c" : {
          "x" : 376,
          "y" : 440
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 376,
          "y" : 440
        }
      }
    }, {
      "edgeId" : 20,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 322,
          "y" : 476
        },
        "to" : {
          "x" : 279,
          "y" : 507
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 271,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1070,
      "y" : 756
    },
    "minX" : 1052,
    "maxX" : 1139,
    "minY" : 740,
    "maxY" : 798,
    "prop" : {
      "x" : 1052,
      "y" : 741,
      "width" : 36,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1056,
      "y" : 745
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1083,
          "y" : 746
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1083,
          "y" : 746
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 267,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1091,
          "y" : 766
        },
        "to" : {
          "x" : 1139,
          "y" : 798
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1109,
            "y" : 776
          },
          "b" : {
            "x" : 1121,
            "y" : 788
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1115,
            "y" : 782
          }
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 784,
    "reactomeId" : 31633,
    "displayName" : "NH4+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 744,
      "y" : 811
    },
    "minX" : 675,
    "maxX" : 772,
    "minY" : 795,
    "maxY" : 827,
    "prop" : {
      "x" : 718,
      "y" : 796,
      "width" : 53,
      "height" : 31
    },
    "textPosition" : {
      "x" : 722,
      "y" : 801
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 766,
          "y" : 801
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 766,
          "y" : 801
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 109,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 715,
          "y" : 811
        },
        "to" : {
          "x" : 675,
          "y" : 813
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 708,
          "y" : 815
        },
        "b" : {
          "x" : 715,
          "y" : 811
        },
        "c" : {
          "x" : 708,
          "y" : 807
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 708,
          "y" : 807
        }
      }
    } ]
  }, {
    "id" : 16,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 527,
      "y" : 482
    },
    "minX" : 443,
    "maxX" : 544,
    "minY" : 402,
    "maxY" : 497,
    "prop" : {
      "x" : 512,
      "y" : 467,
      "width" : 31,
      "height" : 30
    },
    "textPosition" : {
      "x" : 518,
      "y" : 471
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 538,
          "y" : 472
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 538,
          "y" : 472
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 12,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 509,
          "y" : 467
        },
        "to" : {
          "x" : 443,
          "y" : 402
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 501,
          "y" : 465
        },
        "b" : {
          "x" : 509,
          "y" : 467
        },
        "c" : {
          "x" : 507,
          "y" : 459
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 507,
          "y" : 459
        }
      }
    } ]
  }, {
    "id" : 273,
    "reactomeId" : 29450,
    "displayName" : "GSH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1124,
      "y" : 735
    },
    "minX" : 1104,
    "maxX" : 1146,
    "minY" : 719,
    "maxY" : 798,
    "prop" : {
      "x" : 1104,
      "y" : 720,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1107,
      "y" : 724
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1140,
          "y" : 725
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1140,
          "y" : 725
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 267,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1127,
          "y" : 753
        },
        "to" : {
          "x" : 1139,
          "y" : 798
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 1127,
            "y" : 769
          },
          "b" : {
            "x" : 1139,
            "y" : 781
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1133,
            "y" : 775
          }
        }
      }
    } ]
  }, {
    "id" : 785,
    "reactomeId" : 1131953,
    "displayName" : "hydrogen donor",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 641,
      "y" : 739
    },
    "minX" : 587,
    "maxX" : 714,
    "minY" : 722,
    "maxY" : 755,
    "prop" : {
      "x" : 587,
      "y" : 724,
      "width" : 109,
      "height" : 31
    },
    "textPosition" : {
      "x" : 587,
      "y" : 729
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 691,
          "y" : 729
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 691,
          "y" : 729
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 120,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 699,
          "y" : 726
        },
        "to" : {
          "x" : 714,
          "y" : 722
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 17,
    "reactomeId" : 111294,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 463,
      "y" : 495
    },
    "minX" : 443,
    "maxX" : 481,
    "minY" : 402,
    "maxY" : 510,
    "prop" : {
      "x" : 446,
      "y" : 480,
      "width" : 34,
      "height" : 30
    },
    "textPosition" : {
      "x" : 449,
      "y" : 484
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 475,
          "y" : 485
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 475,
          "y" : 485
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 12,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 459,
          "y" : 477
        },
        "to" : {
          "x" : 443,
          "y" : 402
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 454,
          "y" : 471
        },
        "b" : {
          "x" : 459,
          "y" : 477
        },
        "c" : {
          "x" : 461,
          "y" : 469
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 461,
          "y" : 469
        }
      }
    } ]
  }, {
    "id" : 274,
    "reactomeId" : 111745,
    "displayName" : "GSSG",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1304,
      "y" : 761
    },
    "minX" : 1232,
    "maxX" : 1329,
    "minY" : 745,
    "maxY" : 802,
    "prop" : {
      "x" : 1281,
      "y" : 746,
      "width" : 47,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1283,
      "y" : 750
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1323,
          "y" : 751
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1323,
          "y" : 751
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 267,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1278,
          "y" : 774
        },
        "to" : {
          "x" : 1232,
          "y" : 802
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1274,
          "y" : 781
        },
        "b" : {
          "x" : 1278,
          "y" : 774
        },
        "c" : {
          "x" : 1270,
          "y" : 774
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1270,
          "y" : 774
        }
      }
    } ]
  }, {
    "id" : 18,
    "reactomeId" : 174383,
    "displayName" : "MAT1A multimers",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 525,
      "y" : 307
    },
    "minX" : 449,
    "maxX" : 566,
    "minY" : 289,
    "maxY" : 325,
    "prop" : {
      "x" : 485,
      "y" : 289,
      "width" : 81,
      "height" : 36
    },
    "textPosition" : {
      "x" : 491,
      "y" : 289
    },
    "connectors" : [ {
      "edgeId" : 12,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 479,
          "y" : 307
        },
        "to" : {
          "x" : 457,
          "y" : 308
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 453,
          "y" : 308
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 453,
          "y" : 308
        }
      }
    } ]
  }, {
    "id" : 277,
    "reactomeId" : 71680,
    "displayName" : "GSR-2:FAD dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1464,
      "y" : 867
    },
    "minX" : 1412,
    "maxX" : 1523,
    "minY" : 814,
    "maxY" : 887,
    "prop" : {
      "x" : 1412,
      "y" : 847,
      "width" : 105,
      "height" : 40
    },
    "textPosition" : {
      "x" : 1426,
      "y" : 852
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1517,
          "y" : 847
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1517,
          "y" : 847
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 276,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1464,
          "y" : 844
        },
        "to" : {
          "x" : 1464,
          "y" : 822
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1464,
          "y" : 818
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1464,
          "y" : 818
        }
      }
    } ]
  }, {
    "id" : 21,
    "reactomeId" : 5359033,
    "displayName" : "Hist,NAM,Gly",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 207,
      "y" : 458
    },
    "minX" : 165,
    "maxX" : 279,
    "minY" : 447,
    "maxY" : 507,
    "prop" : {
      "x" : 165,
      "y" : 447,
      "width" : 84,
      "height" : 22
    },
    "textPosition" : {
      "x" : 173,
      "y" : 441
    },
    "connectors" : [ {
      "edgeId" : 20,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 223,
          "y" : 475
        },
        "to" : {
          "x" : 279,
          "y" : 507
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 22,
    "reactomeId" : 5359014,
    "displayName" : "MeHist,N1MNA,MeGly",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 366,
      "y" : 639
    },
    "minX" : 278,
    "maxX" : 416,
    "minY" : 608,
    "maxY" : 657,
    "prop" : {
      "x" : 316,
      "y" : 621,
      "width" : 100,
      "height" : 36
    },
    "textPosition" : {
      "x" : 320,
      "y" : 621
    },
    "connectors" : [ {
      "edgeId" : 20,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 310,
          "y" : 621
        },
        "to" : {
          "x" : 278,
          "y" : 608
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 302,
          "y" : 622
        },
        "b" : {
          "x" : 310,
          "y" : 621
        },
        "c" : {
          "x" : 305,
          "y" : 615
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 305,
          "y" : 615
        }
      }
    } ]
  }, {
    "id" : 23,
    "reactomeId" : 5357653,
    "displayName" : "AdeSeHCys",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 278,
      "y" : 677
    },
    "minX" : 237,
    "maxX" : 320,
    "minY" : 608,
    "maxY" : 752,
    "prop" : {
      "x" : 237,
      "y" : 662,
      "width" : 82,
      "height" : 30
    },
    "textPosition" : {
      "x" : 239,
      "y" : 666
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 314,
          "y" : 667
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 314,
          "y" : 667
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 20,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 278,
          "y" : 659
        },
        "to" : {
          "x" : 278,
          "y" : 608
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 274,
          "y" : 652
        },
        "b" : {
          "x" : 278,
          "y" : 659
        },
        "c" : {
          "x" : 282,
          "y" : 652
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 282,
          "y" : 652
        }
      }
    }, {
      "edgeId" : 25,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 278,
          "y" : 695
        },
        "to" : {
          "x" : 278,
          "y" : 752
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 279,
    "reactomeId" : 29450,
    "displayName" : "GSH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1464,
      "y" : 694
    },
    "minX" : 1444,
    "maxX" : 1486,
    "minY" : 678,
    "maxY" : 744,
    "prop" : {
      "x" : 1444,
      "y" : 679,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1447,
      "y" : 683
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1480,
          "y" : 684
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1480,
          "y" : 684
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 276,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1464,
          "y" : 712
        },
        "to" : {
          "x" : 1464,
          "y" : 744
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1468,
          "y" : 719
        },
        "b" : {
          "x" : 1464,
          "y" : 712
        },
        "c" : {
          "x" : 1460,
          "y" : 719
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1460,
          "y" : 719
        }
      }
    } ]
  }, {
    "id" : 1048,
    "reactomeId" : 9939362,
    "displayName" : "unknown selenosugar oxidase",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1198,
      "y" : 401
    },
    "minX" : 1155,
    "maxX" : 1242,
    "minY" : 379,
    "maxY" : 452,
    "prop" : {
      "x" : 1155,
      "y" : 379,
      "width" : 87,
      "height" : 45
    },
    "textPosition" : {
      "x" : 1154,
      "y" : 377
    },
    "connectors" : [ {
      "edgeId" : 229,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1198,
          "y" : 427
        },
        "to" : {
          "x" : 1199,
          "y" : 444
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1199,
          "y" : 448
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1199,
          "y" : 448
        }
      }
    } ]
  }, {
    "id" : 24,
    "reactomeId" : 5359013,
    "displayName" : "MetTrans(1)",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 197,
      "y" : 557
    },
    "minX" : 158,
    "maxX" : 270,
    "minY" : 546,
    "maxY" : 568,
    "prop" : {
      "x" : 158,
      "y" : 546,
      "width" : 79,
      "height" : 22
    },
    "textPosition" : {
      "x" : 164,
      "y" : 540
    },
    "connectors" : [ {
      "edgeId" : 20,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 243,
          "y" : 557
        },
        "to" : {
          "x" : 262,
          "y" : 558
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 266,
          "y" : 558
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 266,
          "y" : 558
        }
      }
    } ]
  }, {
    "id" : 281,
    "reactomeId" : 29364,
    "displayName" : "NADPH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1354,
      "y" : 863
    },
    "minX" : 1325,
    "maxX" : 1417,
    "minY" : 806,
    "maxY" : 878,
    "prop" : {
      "x" : 1325,
      "y" : 848,
      "width" : 59,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1329,
      "y" : 852
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1379,
          "y" : 853
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1379,
          "y" : 853
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 276,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1370,
          "y" : 845
        },
        "to" : {
          "x" : 1417,
          "y" : 806
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 26,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 239,
      "y" : 725
    },
    "minX" : 218,
    "maxX" : 278,
    "minY" : 709,
    "maxY" : 752,
    "prop" : {
      "x" : 218,
      "y" : 710,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 222,
      "y" : 714
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 256,
          "y" : 715
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 256,
          "y" : 715
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 25,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 260,
          "y" : 743
        },
        "to" : {
          "x" : 278,
          "y" : 752
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 27,
    "reactomeId" : 83909,
    "displayName" : "Ade-Rib",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 342,
      "y" : 863
    },
    "minX" : 278,
    "maxX" : 376,
    "minY" : 825,
    "maxY" : 878,
    "prop" : {
      "x" : 309,
      "y" : 848,
      "width" : 66,
      "height" : 30
    },
    "textPosition" : {
      "x" : 314,
      "y" : 852
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 370,
          "y" : 853
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 370,
          "y" : 853
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 25,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 316,
          "y" : 845
        },
        "to" : {
          "x" : 278,
          "y" : 825
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 308,
          "y" : 845
        },
        "b" : {
          "x" : 316,
          "y" : 845
        },
        "c" : {
          "x" : 312,
          "y" : 838
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 312,
          "y" : 838
        }
      }
    } ]
  }, {
    "id" : 284,
    "reactomeId" : 29366,
    "displayName" : "NADP+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1525,
      "y" : 711
    },
    "minX" : 1464,
    "maxX" : 1556,
    "minY" : 695,
    "maxY" : 744,
    "prop" : {
      "x" : 1495,
      "y" : 696,
      "width" : 60,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1499,
      "y" : 700
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1550,
          "y" : 701
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1550,
          "y" : 701
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 276,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1497,
          "y" : 729
        },
        "to" : {
          "x" : 1464,
          "y" : 744
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1492,
          "y" : 736
        },
        "b" : {
          "x" : 1497,
          "y" : 729
        },
        "c" : {
          "x" : 1489,
          "y" : 728
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1489,
          "y" : 728
        }
      }
    } ]
  }, {
    "id" : 28,
    "reactomeId" : 5357702,
    "displayName" : "SeHCys",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 346,
      "y" : 797
    },
    "minX" : 278,
    "maxX" : 403,
    "minY" : 781,
    "maxY" : 825,
    "prop" : {
      "x" : 317,
      "y" : 782,
      "width" : 59,
      "height" : 30
    },
    "textPosition" : {
      "x" : 319,
      "y" : 786
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 371,
          "y" : 787
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 371,
          "y" : 787
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 25,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 314,
          "y" : 809
        },
        "to" : {
          "x" : 278,
          "y" : 825
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 309,
          "y" : 815
        },
        "b" : {
          "x" : 314,
          "y" : 809
        },
        "c" : {
          "x" : 306,
          "y" : 808
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 306,
          "y" : 808
        }
      }
    }, {
      "edgeId" : 103,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 379,
          "y" : 795
        },
        "to" : {
          "x" : 403,
          "y" : 794
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 29,
    "reactomeId" : 174373,
    "displayName" : "AHCY",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 223,
      "y" : 786
    },
    "minX" : 203,
    "maxX" : 270,
    "minY" : 769,
    "maxY" : 797,
    "prop" : {
      "x" : 203,
      "y" : 775,
      "width" : 41,
      "height" : 22
    },
    "textPosition" : {
      "x" : 203,
      "y" : 775
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 244,
          "y" : 775
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 244,
          "y" : 775
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 25,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 247,
          "y" : 787
        },
        "to" : {
          "x" : 262,
          "y" : 788
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 266,
          "y" : 788
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 266,
          "y" : 788
        }
      }
    } ]
  }, {
    "id" : 286,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1361,
      "y" : 762
    },
    "minX" : 1343,
    "maxX" : 1417,
    "minY" : 746,
    "maxY" : 806,
    "prop" : {
      "x" : 1343,
      "y" : 747,
      "width" : 36,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1347,
      "y" : 751
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1374,
          "y" : 752
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1374,
          "y" : 752
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 276,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1382,
          "y" : 776
        },
        "to" : {
          "x" : 1417,
          "y" : 806
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 289,
    "reactomeId" : 5357722,
    "displayName" : "PAPSe",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1118,
      "y" : 1042
    },
    "minX" : 1047,
    "maxX" : 1188,
    "minY" : 993,
    "maxY" : 1075,
    "prop" : {
      "x" : 1092,
      "y" : 1027,
      "width" : 52,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1094,
      "y" : 1031
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1139,
          "y" : 1032
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1139,
          "y" : 1032
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 288,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1096,
          "y" : 1024
        },
        "to" : {
          "x" : 1047,
          "y" : 993
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 300,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1147,
          "y" : 1054
        },
        "to" : {
          "x" : 1188,
          "y" : 1075
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1155,
          "y" : 1054
        },
        "b" : {
          "x" : 1147,
          "y" : 1054
        },
        "c" : {
          "x" : 1151,
          "y" : 1061
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1151,
          "y" : 1061
        }
      }
    } ]
  }, {
    "id" : 290,
    "reactomeId" : 158466,
    "displayName" : "PAP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1141,
      "y" : 903
    },
    "minX" : 1045,
    "maxX" : 1162,
    "minY" : 887,
    "maxY" : 918,
    "prop" : {
      "x" : 1122,
      "y" : 888,
      "width" : 39,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1125,
      "y" : 892
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1156,
          "y" : 893
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1156,
          "y" : 893
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 288,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1119,
          "y" : 902
        },
        "to" : {
          "x" : 1045,
          "y" : 902
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1112,
          "y" : 906
        },
        "b" : {
          "x" : 1119,
          "y" : 902
        },
        "c" : {
          "x" : 1112,
          "y" : 898
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1112,
          "y" : 898
        }
      }
    } ]
  }, {
    "id" : 291,
    "reactomeId" : 5359054,
    "displayName" : "PAPSeR",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1128,
      "y" : 961
    },
    "minX" : 1054,
    "maxX" : 1154,
    "minY" : 950,
    "maxY" : 972,
    "prop" : {
      "x" : 1102,
      "y" : 950,
      "width" : 52,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1104,
      "y" : 944
    },
    "connectors" : [ {
      "edgeId" : 288,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1099,
          "y" : 960
        },
        "to" : {
          "x" : 1062,
          "y" : 959
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1058,
          "y" : 959
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1058,
          "y" : 959
        }
      }
    } ]
  }, {
    "id" : 293,
    "reactomeId" : 29364,
    "displayName" : "NADPH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1038,
      "y" : 1047
    },
    "minX" : 1009,
    "maxX" : 1069,
    "minY" : 993,
    "maxY" : 1062,
    "prop" : {
      "x" : 1009,
      "y" : 1032,
      "width" : 59,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1013,
      "y" : 1036
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1063,
          "y" : 1037
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1063,
          "y" : 1037
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 288,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1040,
          "y" : 1029
        },
        "to" : {
          "x" : 1047,
          "y" : 993
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 295,
    "reactomeId" : 29366,
    "displayName" : "NADP+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 987,
      "y" : 890
    },
    "minX" : 957,
    "maxX" : 1045,
    "minY" : 874,
    "maxY" : 905,
    "prop" : {
      "x" : 957,
      "y" : 875,
      "width" : 60,
      "height" : 30
    },
    "textPosition" : {
      "x" : 961,
      "y" : 879
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1012,
          "y" : 880
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1012,
          "y" : 880
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 288,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1020,
          "y" : 896
        },
        "to" : {
          "x" : 1045,
          "y" : 902
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1028,
          "y" : 894
        },
        "b" : {
          "x" : 1020,
          "y" : 896
        },
        "c" : {
          "x" : 1026,
          "y" : 902
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1026,
          "y" : 902
        }
      }
    } ]
  }, {
    "id" : 809,
    "reactomeId" : 1130886,
    "displayName" : "hydrogen acceptor",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 579,
      "y" : 628
    },
    "minX" : 517,
    "maxX" : 723,
    "minY" : 612,
    "maxY" : 644,
    "prop" : {
      "x" : 517,
      "y" : 613,
      "width" : 125,
      "height" : 31
    },
    "textPosition" : {
      "x" : 544,
      "y" : 611
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 637,
          "y" : 618
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 637,
          "y" : 618
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 120,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 645,
          "y" : 634
        },
        "to" : {
          "x" : 723,
          "y" : 644
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 652,
          "y" : 631
        },
        "b" : {
          "x" : 645,
          "y" : 634
        },
        "c" : {
          "x" : 651,
          "y" : 639
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 651,
          "y" : 639
        }
      }
    } ]
  }, {
    "id" : 297,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 981,
      "y" : 1017
    },
    "minX" : 963,
    "maxX" : 1047,
    "minY" : 993,
    "maxY" : 1032,
    "prop" : {
      "x" : 963,
      "y" : 1002,
      "width" : 36,
      "height" : 30
    },
    "textPosition" : {
      "x" : 967,
      "y" : 1006
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 994,
          "y" : 1007
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 994,
          "y" : 1007
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 288,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1002,
          "y" : 1010
        },
        "to" : {
          "x" : 1047,
          "y" : 993
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 811,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 670,
      "y" : 613
    },
    "minX" : 652,
    "maxX" : 723,
    "minY" : 597,
    "maxY" : 644,
    "prop" : {
      "x" : 652,
      "y" : 598,
      "width" : 36,
      "height" : 30
    },
    "textPosition" : {
      "x" : 656,
      "y" : 602
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 683,
          "y" : 603
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 683,
          "y" : 603
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 120,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 691,
          "y" : 623
        },
        "to" : {
          "x" : 723,
          "y" : 644
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 699,
          "y" : 623
        },
        "b" : {
          "x" : 691,
          "y" : 623
        },
        "c" : {
          "x" : 695,
          "y" : 630
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 695,
          "y" : 630
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 301,
    "reactomeId" : 5357645,
    "displayName" : "APSe",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1328,
      "y" : 1042
    },
    "minX" : 1278,
    "maxX" : 1399,
    "minY" : 1026,
    "maxY" : 1073,
    "prop" : {
      "x" : 1306,
      "y" : 1027,
      "width" : 45,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1308,
      "y" : 1031
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1346,
          "y" : 1032
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1346,
          "y" : 1032
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 300,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1303,
          "y" : 1055
        },
        "to" : {
          "x" : 1278,
          "y" : 1073
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 306,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1354,
          "y" : 1051
        },
        "to" : {
          "x" : 1399,
          "y" : 1072
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1362,
          "y" : 1050
        },
        "b" : {
          "x" : 1354,
          "y" : 1051
        },
        "c" : {
          "x" : 1359,
          "y" : 1058
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1359,
          "y" : 1058
        }
      }
    } ]
  }, {
    "id" : 302,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1316,
      "y" : 1117
    },
    "minX" : 1278,
    "maxX" : 1337,
    "minY" : 1073,
    "maxY" : 1132,
    "prop" : {
      "x" : 1296,
      "y" : 1102,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1300,
      "y" : 1106
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1331,
          "y" : 1107
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1331,
          "y" : 1107
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 300,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1303,
          "y" : 1099
        },
        "to" : {
          "x" : 1278,
          "y" : 1073
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 303,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1146,
      "y" : 1120
    },
    "minX" : 1126,
    "maxX" : 1188,
    "minY" : 1075,
    "maxY" : 1135,
    "prop" : {
      "x" : 1126,
      "y" : 1105,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1130,
      "y" : 1109
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1162,
          "y" : 1110
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1162,
          "y" : 1110
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 300,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1160,
          "y" : 1102
        },
        "to" : {
          "x" : 1188,
          "y" : 1075
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1162,
          "y" : 1094
        },
        "b" : {
          "x" : 1160,
          "y" : 1102
        },
        "c" : {
          "x" : 1168,
          "y" : 1100
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1168,
          "y" : 1100
        }
      }
    } ]
  }, {
    "id" : 304,
    "reactomeId" : 174400,
    "displayName" : "PAPSS1,2",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1236,
      "y" : 1139
    },
    "minX" : 1205,
    "maxX" : 1268,
    "minY" : 1082,
    "maxY" : 1150,
    "prop" : {
      "x" : 1205,
      "y" : 1128,
      "width" : 63,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1206,
      "y" : 1122
    },
    "connectors" : [ {
      "edgeId" : 300,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1235,
          "y" : 1122
        },
        "to" : {
          "x" : 1234,
          "y" : 1090
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1233,
          "y" : 1086
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1233,
          "y" : 1086
        }
      }
    } ]
  }, {
    "id" : 307,
    "reactomeId" : 5357662,
    "displayName" : "selenate",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1534,
      "y" : 1035
    },
    "minX" : 1484,
    "maxX" : 1567,
    "minY" : 1019,
    "maxY" : 1072,
    "prop" : {
      "x" : 1502,
      "y" : 1020,
      "width" : 64,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1502,
      "y" : 1024
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1561,
          "y" : 1025
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1561,
          "y" : 1025
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 306,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1513,
          "y" : 1053
        },
        "to" : {
          "x" : 1484,
          "y" : 1072
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 308,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1520,
      "y" : 1116
    },
    "minX" : 1484,
    "maxX" : 1541,
    "minY" : 1072,
    "maxY" : 1131,
    "prop" : {
      "x" : 1500,
      "y" : 1101,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1504,
      "y" : 1105
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1535,
          "y" : 1106
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1535,
          "y" : 1106
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 306,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1507,
          "y" : 1098
        },
        "to" : {
          "x" : 1484,
          "y" : 1072
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 309,
    "reactomeId" : 111294,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1364,
      "y" : 1116
    },
    "minX" : 1347,
    "maxX" : 1399,
    "minY" : 1072,
    "maxY" : 1131,
    "prop" : {
      "x" : 1347,
      "y" : 1101,
      "width" : 34,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1350,
      "y" : 1105
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1376,
          "y" : 1106
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1376,
          "y" : 1106
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 306,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1375,
          "y" : 1098
        },
        "to" : {
          "x" : 1399,
          "y" : 1072
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1377,
          "y" : 1090
        },
        "b" : {
          "x" : 1375,
          "y" : 1098
        },
        "c" : {
          "x" : 1383,
          "y" : 1096
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1383,
          "y" : 1096
        }
      }
    } ]
  }, {
    "id" : 310,
    "reactomeId" : 174400,
    "displayName" : "PAPSS1,2",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1444,
      "y" : 1136
    },
    "minX" : 1413,
    "maxX" : 1476,
    "minY" : 1080,
    "maxY" : 1147,
    "prop" : {
      "x" : 1413,
      "y" : 1125,
      "width" : 63,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1414,
      "y" : 1119
    },
    "connectors" : [ {
      "edgeId" : 306,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1443,
          "y" : 1119
        },
        "to" : {
          "x" : 1443,
          "y" : 1088
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1443,
          "y" : 1084
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1443,
          "y" : 1084
        }
      }
    } ]
  }, {
    "id" : 313,
    "reactomeId" : 379742,
    "displayName" : "tRNA(Met)",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 525,
      "y" : 104
    },
    "minX" : 488,
    "maxX" : 611,
    "minY" : 89,
    "maxY" : 125,
    "prop" : {
      "x" : 488,
      "y" : 89,
      "width" : 75,
      "height" : 30
    },
    "textPosition" : {
      "x" : 490,
      "y" : 93
    },
    "connectors" : [ {
      "edgeId" : 312,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 566,
          "y" : 113
        },
        "to" : {
          "x" : 611,
          "y" : 125
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 314,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 571,
      "y" : 67
    },
    "minX" : 551,
    "maxX" : 611,
    "minY" : 51,
    "maxY" : 125,
    "prop" : {
      "x" : 551,
      "y" : 52,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 555,
      "y" : 56
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 586,
          "y" : 57
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 586,
          "y" : 57
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 312,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 581,
          "y" : 85
        },
        "to" : {
          "x" : 611,
          "y" : 125
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 315,
    "reactomeId" : 76577,
    "displayName" : "AMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 784,
      "y" : 157
    },
    "minX" : 715,
    "maxX" : 806,
    "minY" : 123,
    "maxY" : 172,
    "prop" : {
      "x" : 763,
      "y" : 142,
      "width" : 42,
      "height" : 30
    },
    "textPosition" : {
      "x" : 767,
      "y" : 146
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 800,
          "y" : 147
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 800,
          "y" : 147
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 312,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 760,
          "y" : 146
        },
        "to" : {
          "x" : 715,
          "y" : 123
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 752,
          "y" : 146
        },
        "b" : {
          "x" : 760,
          "y" : 146
        },
        "c" : {
          "x" : 756,
          "y" : 139
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 756,
          "y" : 139
        }
      }
    } ]
  }, {
    "id" : 316,
    "reactomeId" : 5357731,
    "displayName" : "SeMet-tRNA(Met)",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 851,
      "y" : 122
    },
    "minX" : 715,
    "maxX" : 909,
    "minY" : 107,
    "maxY" : 137,
    "prop" : {
      "x" : 793,
      "y" : 107,
      "width" : 116,
      "height" : 30
    },
    "textPosition" : {
      "x" : 794,
      "y" : 111
    },
    "connectors" : [ {
      "edgeId" : 312,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 790,
          "y" : 122
        },
        "to" : {
          "x" : 715,
          "y" : 123
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 783,
          "y" : 126
        },
        "b" : {
          "x" : 790,
          "y" : 122
        },
        "c" : {
          "x" : 783,
          "y" : 118
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 783,
          "y" : 118
        }
      }
    } ]
  }, {
    "id" : 317,
    "reactomeId" : 379688,
    "displayName" : "aminoacyl-tRNA synthetase multienzyme complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 663,
      "y" : 62
    },
    "minX" : 610,
    "maxX" : 722,
    "minY" : 24,
    "maxY" : 116,
    "prop" : {
      "x" : 610,
      "y" : 30,
      "width" : 106,
      "height" : 64
    },
    "textPosition" : {
      "x" : 609,
      "y" : 31
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 716,
          "y" : 30
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 716,
          "y" : 30
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 312,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 660,
          "y" : 97
        },
        "to" : {
          "x" : 660,
          "y" : 108
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 659,
          "y" : 112
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 659,
          "y" : 112
        }
      }
    } ]
  }, {
    "id" : 319,
    "reactomeId" : 111294,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 782,
      "y" : 84
    },
    "minX" : 715,
    "maxX" : 800,
    "minY" : 68,
    "maxY" : 123,
    "prop" : {
      "x" : 765,
      "y" : 69,
      "width" : 34,
      "height" : 30
    },
    "textPosition" : {
      "x" : 768,
      "y" : 73
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 794,
          "y" : 74
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 794,
          "y" : 74
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 312,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 762,
          "y" : 93
        },
        "to" : {
          "x" : 715,
          "y" : 123
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 758,
          "y" : 100
        },
        "b" : {
          "x" : 762,
          "y" : 93
        },
        "c" : {
          "x" : 754,
          "y" : 93
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 754,
          "y" : 93
        }
      }
    } ]
  }, {
    "id" : 835,
    "reactomeId" : 29398,
    "displayName" : "PYR",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 810,
      "y" : 371
    },
    "minX" : 791,
    "maxX" : 831,
    "minY" : 314,
    "maxY" : 387,
    "prop" : {
      "x" : 791,
      "y" : 356,
      "width" : 39,
      "height" : 31
    },
    "textPosition" : {
      "x" : 795,
      "y" : 361
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 825,
          "y" : 361
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 825,
          "y" : 361
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 127,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 809,
          "y" : 353
        },
        "to" : {
          "x" : 807,
          "y" : 314
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 805,
          "y" : 346
        },
        "b" : {
          "x" : 809,
          "y" : 353
        },
        "c" : {
          "x" : 813,
          "y" : 346
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 813,
          "y" : 346
        }
      }
    } ]
  }, {
    "id" : 324,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 199,
      "y" : 916
    },
    "minX" : 179,
    "maxX" : 266,
    "minY" : 900,
    "maxY" : 942,
    "prop" : {
      "x" : 179,
      "y" : 901,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 183,
      "y" : 905
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 214,
          "y" : 906
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 214,
          "y" : 906
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 323,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 222,
          "y" : 923
        },
        "to" : {
          "x" : 266,
          "y" : 942
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 837,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 216,
      "y" : 1071
    },
    "minX" : 198,
    "maxX" : 265,
    "minY" : 1014,
    "maxY" : 1086,
    "prop" : {
      "x" : 198,
      "y" : 1056,
      "width" : 36,
      "height" : 30
    },
    "textPosition" : {
      "x" : 202,
      "y" : 1060
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 229,
          "y" : 1061
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 229,
          "y" : 1061
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 323,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 228,
          "y" : 1053
        },
        "to" : {
          "x" : 265,
          "y" : 1014
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 230,
          "y" : 1045
        },
        "b" : {
          "x" : 228,
          "y" : 1053
        },
        "c" : {
          "x" : 236,
          "y" : 1051
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 236,
          "y" : 1051
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 325,
    "reactomeId" : 5357732,
    "displayName" : "tRNA(Sec)",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 355,
      "y" : 926
    },
    "minX" : 266,
    "maxX" : 715,
    "minY" : 911,
    "maxY" : 1118,
    "prop" : {
      "x" : 319,
      "y" : 911,
      "width" : 73,
      "height" : 30
    },
    "textPosition" : {
      "x" : 320,
      "y" : 915
    },
    "connectors" : [ {
      "edgeId" : 323,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 316,
          "y" : 932
        },
        "to" : {
          "x" : 266,
          "y" : 942
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 356,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 383,
          "y" : 944
        },
        "to" : {
          "x" : 715,
          "y" : 1118
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 391,
          "y" : 944
        },
        "b" : {
          "x" : 383,
          "y" : 944
        },
        "c" : {
          "x" : 387,
          "y" : 951
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 387,
          "y" : 951
        }
      }
    } ]
  }, {
    "id" : 326,
    "reactomeId" : 5357730,
    "displayName" : "Ser-tRNA(Sec)",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 367,
      "y" : 1047
    },
    "minX" : 265,
    "maxX" : 416,
    "minY" : 1014,
    "maxY" : 1128,
    "prop" : {
      "x" : 318,
      "y" : 1032,
      "width" : 98,
      "height" : 30
    },
    "textPosition" : {
      "x" : 319,
      "y" : 1036
    },
    "connectors" : [ {
      "edgeId" : 323,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 320,
          "y" : 1029
        },
        "to" : {
          "x" : 265,
          "y" : 1014
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 312,
          "y" : 1031
        },
        "b" : {
          "x" : 320,
          "y" : 1029
        },
        "c" : {
          "x" : 314,
          "y" : 1023
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 314,
          "y" : 1023
        }
      }
    }, {
      "edgeId" : 333,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 366,
          "y" : 1065
        },
        "to" : {
          "x" : 366,
          "y" : 1128
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 327,
    "reactomeId" : 379557,
    "displayName" : "SARS dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 199,
      "y" : 981
    },
    "minX" : 162,
    "maxX" : 257,
    "minY" : 964,
    "maxY" : 992,
    "prop" : {
      "x" : 162,
      "y" : 970,
      "width" : 75,
      "height" : 22
    },
    "textPosition" : {
      "x" : 177,
      "y" : 957
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 237,
          "y" : 970
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 237,
          "y" : 970
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 323,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 240,
          "y" : 982
        },
        "to" : {
          "x" : 249,
          "y" : 982
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 253,
          "y" : 983
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 253,
          "y" : 983
        }
      }
    } ]
  }, {
    "id" : 328,
    "reactomeId" : 200736,
    "displayName" : "L-Ser",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 265,
      "y" : 899
    },
    "minX" : 248,
    "maxX" : 284,
    "minY" : 883,
    "maxY" : 942,
    "prop" : {
      "x" : 248,
      "y" : 884,
      "width" : 35,
      "height" : 30
    },
    "textPosition" : {
      "x" : 251,
      "y" : 882
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 278,
          "y" : 889
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 278,
          "y" : 889
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 323,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 265,
          "y" : 917
        },
        "to" : {
          "x" : 266,
          "y" : 942
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 330,
    "reactomeId" : 111294,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 266,
      "y" : 1069
    },
    "minX" : 249,
    "maxX" : 284,
    "minY" : 1014,
    "maxY" : 1084,
    "prop" : {
      "x" : 249,
      "y" : 1054,
      "width" : 34,
      "height" : 30
    },
    "textPosition" : {
      "x" : 252,
      "y" : 1058
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 278,
          "y" : 1059
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 278,
          "y" : 1059
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 323,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 265,
          "y" : 1051
        },
        "to" : {
          "x" : 265,
          "y" : 1014
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 261,
          "y" : 1044
        },
        "b" : {
          "x" : 265,
          "y" : 1051
        },
        "c" : {
          "x" : 269,
          "y" : 1044
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 269,
          "y" : 1044
        }
      }
    } ]
  }, {
    "id" : 331,
    "reactomeId" : 76577,
    "displayName" : "AMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 205,
      "y" : 1032
    },
    "minX" : 184,
    "maxX" : 265,
    "minY" : 1014,
    "maxY" : 1047,
    "prop" : {
      "x" : 184,
      "y" : 1017,
      "width" : 42,
      "height" : 30
    },
    "textPosition" : {
      "x" : 188,
      "y" : 1021
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 221,
          "y" : 1022
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 221,
          "y" : 1022
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 323,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 229,
          "y" : 1025
        },
        "to" : {
          "x" : 265,
          "y" : 1014
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 234,
          "y" : 1019
        },
        "b" : {
          "x" : 229,
          "y" : 1025
        },
        "c" : {
          "x" : 237,
          "y" : 1027
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 237,
          "y" : 1027
        }
      }
    } ]
  }, {
    "id" : 334,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 417,
      "y" : 1091
    },
    "minX" : 366,
    "maxX" : 438,
    "minY" : 1075,
    "maxY" : 1128,
    "prop" : {
      "x" : 397,
      "y" : 1076,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 401,
      "y" : 1080
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 432,
          "y" : 1081
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 432,
          "y" : 1081
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 333,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 394,
          "y" : 1105
        },
        "to" : {
          "x" : 366,
          "y" : 1128
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 335,
    "reactomeId" : 29370,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 314,
      "y" : 1221
    },
    "minX" : 294,
    "maxX" : 367,
    "minY" : 1200,
    "maxY" : 1236,
    "prop" : {
      "x" : 294,
      "y" : 1206,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 298,
      "y" : 1210
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 330,
          "y" : 1211
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 330,
          "y" : 1211
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 333,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 338,
          "y" : 1212
        },
        "to" : {
          "x" : 367,
          "y" : 1200
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 343,
          "y" : 1206
        },
        "b" : {
          "x" : 338,
          "y" : 1212
        },
        "c" : {
          "x" : 346,
          "y" : 1213
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 346,
          "y" : 1213
        }
      }
    } ]
  }, {
    "id" : 336,
    "reactomeId" : 5357712,
    "displayName" : "Sep-tRNA(Sec)",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 423,
      "y" : 1235
    },
    "minX" : 367,
    "maxX" : 474,
    "minY" : 1200,
    "maxY" : 1296,
    "prop" : {
      "x" : 373,
      "y" : 1220,
      "width" : 101,
      "height" : 30
    },
    "textPosition" : {
      "x" : 374,
      "y" : 1224
    },
    "connectors" : [ {
      "edgeId" : 333,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 399,
          "y" : 1217
        },
        "to" : {
          "x" : 367,
          "y" : 1200
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 391,
          "y" : 1217
        },
        "b" : {
          "x" : 399,
          "y" : 1217
        },
        "c" : {
          "x" : 395,
          "y" : 1210
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 395,
          "y" : 1210
        }
      }
    }, {
      "edgeId" : 340,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 423,
          "y" : 1253
        },
        "to" : {
          "x" : 424,
          "y" : 1296
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 337,
    "reactomeId" : 5359062,
    "displayName" : "PSTK:Mg2+",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 288,
      "y" : 1161
    },
    "minX" : 250,
    "maxX" : 359,
    "minY" : 1144,
    "maxY" : 1172,
    "prop" : {
      "x" : 250,
      "y" : 1150,
      "width" : 77,
      "height" : 22
    },
    "textPosition" : {
      "x" : 266,
      "y" : 1137
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 327,
          "y" : 1150
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 327,
          "y" : 1150
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 333,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 330,
          "y" : 1161
        },
        "to" : {
          "x" : 351,
          "y" : 1162
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 355,
          "y" : 1162
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 355,
          "y" : 1162
        }
      }
    } ]
  }, {
    "id" : 343,
    "reactomeId" : 5357708,
    "displayName" : "Sec-tRNA(Sec)",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 438,
      "y" : 1411
    },
    "minX" : 389,
    "maxX" : 549,
    "minY" : 1368,
    "maxY" : 1426,
    "prop" : {
      "x" : 389,
      "y" : 1396,
      "width" : 99,
      "height" : 30
    },
    "textPosition" : {
      "x" : 389,
      "y" : 1400
    },
    "connectors" : [ {
      "edgeId" : 340,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 433,
          "y" : 1393
        },
        "to" : {
          "x" : 426,
          "y" : 1368
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 427,
          "y" : 1387
        },
        "b" : {
          "x" : 433,
          "y" : 1393
        },
        "c" : {
          "x" : 435,
          "y" : 1385
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 435,
          "y" : 1385
        }
      }
    }, {
      "edgeId" : 348,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 491,
          "y" : 1411
        },
        "to" : {
          "x" : 549,
          "y" : 1411
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 345,
    "reactomeId" : 5357724,
    "displayName" : "PXLP-K284-SEPSECS tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 516,
      "y" : 1334
    },
    "minX" : 433,
    "maxX" : 579,
    "minY" : 1310,
    "maxY" : 1352,
    "prop" : {
      "x" : 459,
      "y" : 1316,
      "width" : 114,
      "height" : 36
    },
    "textPosition" : {
      "x" : 478,
      "y" : 1303
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 573,
          "y" : 1316
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 573,
          "y" : 1316
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 340,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 456,
          "y" : 1336
        },
        "to" : {
          "x" : 441,
          "y" : 1337
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 437,
          "y" : 1337
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 437,
          "y" : 1337
        }
      }
    } ]
  }, {
    "id" : 349,
    "reactomeId" : 5359045,
    "displayName" : "EEFSEC:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 518,
      "y" : 1461
    },
    "minX" : 479,
    "maxX" : 596,
    "minY" : 1411,
    "maxY" : 1472,
    "prop" : {
      "x" : 479,
      "y" : 1450,
      "width" : 78,
      "height" : 22
    },
    "textPosition" : {
      "x" : 488,
      "y" : 1437
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 557,
          "y" : 1450
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 557,
          "y" : 1450
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 348,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 524,
          "y" : 1447
        },
        "to" : {
          "x" : 549,
          "y" : 1411
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 348,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 560,
          "y" : 1458
        },
        "to" : {
          "x" : 593,
          "y" : 1457
        }
      }, {
        "from" : {
          "x" : 593,
          "y" : 1457
        },
        "to" : {
          "x" : 592,
          "y" : 1427
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 592,
          "y" : 1423
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 592,
          "y" : 1423
        }
      }
    } ]
  }, {
    "id" : 350,
    "reactomeId" : 5359036,
    "displayName" : "Sec-tRNA(Sec):EEFSEC:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 700,
      "y" : 1411
    },
    "minX" : 653,
    "maxX" : 813,
    "minY" : 1387,
    "maxY" : 1429,
    "prop" : {
      "x" : 653,
      "y" : 1393,
      "width" : 95,
      "height" : 36
    },
    "textPosition" : {
      "x" : 659,
      "y" : 1380
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 748,
          "y" : 1393
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 748,
          "y" : 1393
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 348,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 351,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 751,
          "y" : 1411
        },
        "to" : {
          "x" : 813,
          "y" : 1413
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 352,
    "reactomeId" : 72505,
    "displayName" : "80S:Met-tRNAi:mRNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 754,
      "y" : 1345
    },
    "minX" : 705,
    "maxX" : 813,
    "minY" : 1321,
    "maxY" : 1413,
    "prop" : {
      "x" : 705,
      "y" : 1327,
      "width" : 99,
      "height" : 36
    },
    "textPosition" : {
      "x" : 714,
      "y" : 1328
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 804,
          "y" : 1327
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 804,
          "y" : 1327
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 351,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 769,
          "y" : 1366
        },
        "to" : {
          "x" : 813,
          "y" : 1413
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 353,
    "reactomeId" : 5357715,
    "displayName" : "SECISBP2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 765,
      "y" : 1464
    },
    "minX" : 735,
    "maxX" : 873,
    "minY" : 1413,
    "maxY" : 1475,
    "prop" : {
      "x" : 735,
      "y" : 1453,
      "width" : 61,
      "height" : 22
    },
    "textPosition" : {
      "x" : 736,
      "y" : 1447
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 796,
          "y" : 1453
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 796,
          "y" : 1453
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 351,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 775,
          "y" : 1450
        },
        "to" : {
          "x" : 813,
          "y" : 1413
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 351,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 799,
          "y" : 1463
        },
        "to" : {
          "x" : 869,
          "y" : 1462
        }
      }, {
        "from" : {
          "x" : 869,
          "y" : 1462
        },
        "to" : {
          "x" : 869,
          "y" : 1428
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 869,
          "y" : 1424
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 869,
          "y" : 1424
        }
      }
    } ]
  }, {
    "id" : 354,
    "reactomeId" : 5359044,
    "displayName" : "80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 867,
      "y" : 1254
    },
    "minX" : 802,
    "maxX" : 954,
    "minY" : 1117,
    "maxY" : 1286,
    "prop" : {
      "x" : 802,
      "y" : 1222,
      "width" : 131,
      "height" : 64
    },
    "textPosition" : {
      "x" : 812,
      "y" : 1223
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 933,
          "y" : 1222
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 933,
          "y" : 1222
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 351,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 356,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 936,
          "y" : 1250
        },
        "to" : {
          "x" : 954,
          "y" : 1250
        }
      }, {
        "from" : {
          "x" : 954,
          "y" : 1250
        },
        "to" : {
          "x" : 952,
          "y" : 1117
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 356,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 866,
          "y" : 1219
        },
        "to" : {
          "x" : 863,
          "y" : 1133
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 863,
          "y" : 1129
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 863,
          "y" : 1129
        }
      }
    } ]
  }, {
    "id" : 357,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1008,
      "y" : 1117
    },
    "minX" : 952,
    "maxX" : 1031,
    "minY" : 1101,
    "maxY" : 1132,
    "prop" : {
      "x" : 987,
      "y" : 1102,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 991,
      "y" : 1106
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1025,
          "y" : 1107
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1025,
          "y" : 1107
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 356,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 984,
          "y" : 1117
        },
        "to" : {
          "x" : 952,
          "y" : 1117
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 358,
    "reactomeId" : 5359053,
    "displayName" : "80S:Met-tRNAi:mRNA:SECISBP2:Sec",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 628,
      "y" : 1013
    },
    "minX" : 566,
    "maxX" : 715,
    "minY" : 989,
    "maxY" : 1118,
    "prop" : {
      "x" : 566,
      "y" : 995,
      "width" : 124,
      "height" : 36
    },
    "textPosition" : {
      "x" : 572,
      "y" : 982
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 690,
          "y" : 995
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 690,
          "y" : 995
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 356,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 642,
          "y" : 1034
        },
        "to" : {
          "x" : 715,
          "y" : 1118
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 650,
          "y" : 1037
        },
        "b" : {
          "x" : 642,
          "y" : 1034
        },
        "c" : {
          "x" : 644,
          "y" : 1042
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 644,
          "y" : 1042
        }
      }
    } ]
  }, {
    "id" : 359,
    "reactomeId" : 5359051,
    "displayName" : "EEFSEC:GDP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 750,
      "y" : 1026
    },
    "minX" : 711,
    "maxX" : 796,
    "minY" : 1009,
    "maxY" : 1118,
    "prop" : {
      "x" : 711,
      "y" : 1015,
      "width" : 79,
      "height" : 22
    },
    "textPosition" : {
      "x" : 721,
      "y" : 1002
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 790,
          "y" : 1015
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 790,
          "y" : 1015
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 356,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 745,
          "y" : 1040
        },
        "to" : {
          "x" : 715,
          "y" : 1118
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 746,
          "y" : 1048
        },
        "b" : {
          "x" : 745,
          "y" : 1040
        },
        "c" : {
          "x" : 739,
          "y" : 1045
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 739,
          "y" : 1045
        }
      }
    } ]
  }, {
    "id" : 104,
    "reactomeId" : 200736,
    "displayName" : "L-Ser",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 394,
      "y" : 735
    },
    "minX" : 371,
    "maxX" : 418,
    "minY" : 717,
    "maxY" : 794,
    "prop" : {
      "x" : 371,
      "y" : 718,
      "width" : 46,
      "height" : 34
    },
    "textPosition" : {
      "x" : 374,
      "y" : 724
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 412,
          "y" : 723
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 412,
          "y" : 723
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 103,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 396,
          "y" : 755
        },
        "to" : {
          "x" : 403,
          "y" : 794
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 360,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 615,
      "y" : 1162
    },
    "minX" : 601,
    "maxX" : 715,
    "minY" : 1118,
    "maxY" : 1175,
    "prop" : {
      "x" : 601,
      "y" : 1150,
      "width" : 29,
      "height" : 25
    },
    "textPosition" : {
      "x" : 606,
      "y" : 1152
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 625,
          "y" : 1155
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 625,
          "y" : 1155
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 356,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 633,
          "y" : 1155
        },
        "to" : {
          "x" : 715,
          "y" : 1118
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 638,
          "y" : 1149
        },
        "b" : {
          "x" : 633,
          "y" : 1155
        },
        "c" : {
          "x" : 641,
          "y" : 1156
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 641,
          "y" : 1156
        }
      }
    } ]
  }, {
    "id" : 105,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 548,
      "y" : 856
    },
    "minX" : 496,
    "maxX" : 613,
    "minY" : 793,
    "maxY" : 871,
    "prop" : {
      "x" : 527,
      "y" : 841,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 531,
      "y" : 845
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 565,
          "y" : 846
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 565,
          "y" : 846
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 103,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 535,
          "y" : 838
        },
        "to" : {
          "x" : 496,
          "y" : 793
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 527,
          "y" : 835
        },
        "b" : {
          "x" : 535,
          "y" : 838
        },
        "c" : {
          "x" : 533,
          "y" : 830
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 533,
          "y" : 830
        }
      }
    }, {
      "edgeId" : 109,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 573,
          "y" : 842
        },
        "to" : {
          "x" : 613,
          "y" : 814
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 361,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1099,
      "y" : 856
    },
    "minX" : 1045,
    "maxX" : 1122,
    "minY" : 840,
    "maxY" : 902,
    "prop" : {
      "x" : 1078,
      "y" : 841,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1082,
      "y" : 845
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1116,
          "y" : 846
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1116,
          "y" : 846
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 288,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1081,
          "y" : 874
        },
        "to" : {
          "x" : 1045,
          "y" : 902
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1078,
          "y" : 881
        },
        "b" : {
          "x" : 1081,
          "y" : 874
        },
        "c" : {
          "x" : 1073,
          "y" : 875
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1073,
          "y" : 875
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 106,
    "reactomeId" : 5357703,
    "displayName" : "SeCysta",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 543,
      "y" : 765
    },
    "minX" : 496,
    "maxX" : 613,
    "minY" : 749,
    "maxY" : 814,
    "prop" : {
      "x" : 513,
      "y" : 750,
      "width" : 61,
      "height" : 30
    },
    "textPosition" : {
      "x" : 514,
      "y" : 754
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 569,
          "y" : 755
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 569,
          "y" : 755
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 103,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 517,
          "y" : 783
        },
        "to" : {
          "x" : 496,
          "y" : 793
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 512,
          "y" : 790
        },
        "b" : {
          "x" : 517,
          "y" : 783
        },
        "c" : {
          "x" : 509,
          "y" : 782
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 509,
          "y" : 782
        }
      }
    }, {
      "edgeId" : 109,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 564,
          "y" : 783
        },
        "to" : {
          "x" : 613,
          "y" : 814
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 107,
    "reactomeId" : 1614610,
    "displayName" : "PXLP-K119-CBS tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 453,
      "y" : 838
    },
    "minX" : 411,
    "maxX" : 501,
    "minY" : 801,
    "maxY" : 849,
    "prop" : {
      "x" : 411,
      "y" : 827,
      "width" : 84,
      "height" : 22
    },
    "textPosition" : {
      "x" : 415,
      "y" : 800
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 495,
          "y" : 827
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 495,
          "y" : 827
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 103,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 452,
          "y" : 824
        },
        "to" : {
          "x" : 451,
          "y" : 809
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 451,
          "y" : 805
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 451,
          "y" : 805
        }
      }
    } ]
  }, {
    "id" : 363,
    "reactomeId" : 29364,
    "displayName" : "NADPH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 904,
      "y" : 840
    },
    "minX" : 875,
    "maxX" : 935,
    "minY" : 764,
    "maxY" : 855,
    "prop" : {
      "x" : 875,
      "y" : 825,
      "width" : 59,
      "height" : 30
    },
    "textPosition" : {
      "x" : 879,
      "y" : 829
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 929,
          "y" : 830
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 929,
          "y" : 830
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 250,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 904,
          "y" : 822
        },
        "to" : {
          "x" : 906,
          "y" : 764
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 899,
            "y" : 787
          },
          "b" : {
            "x" : 911,
            "y" : 799
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 905,
            "y" : 793
          }
        }
      }
    } ]
  }, {
    "id" : 365,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 967,
      "y" : 839
    },
    "minX" : 906,
    "maxX" : 986,
    "minY" : 764,
    "maxY" : 854,
    "prop" : {
      "x" : 949,
      "y" : 824,
      "width" : 36,
      "height" : 30
    },
    "textPosition" : {
      "x" : 953,
      "y" : 828
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 980,
          "y" : 829
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 980,
          "y" : 829
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 250,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 954,
          "y" : 821
        },
        "to" : {
          "x" : 906,
          "y" : 764
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 924,
            "y" : 786
          },
          "b" : {
            "x" : 936,
            "y" : 798
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 930,
            "y" : 792
          }
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 111,
    "reactomeId" : 5357697,
    "displayName" : "Sec",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 720,
      "y" : 768
    },
    "minX" : 675,
    "maxX" : 739,
    "minY" : 722,
    "maxY" : 813,
    "prop" : {
      "x" : 702,
      "y" : 753,
      "width" : 36,
      "height" : 30
    },
    "textPosition" : {
      "x" : 704,
      "y" : 757
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 733,
          "y" : 758
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 733,
          "y" : 758
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 109,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 705,
          "y" : 786
        },
        "to" : {
          "x" : 675,
          "y" : 813
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 703,
          "y" : 794
        },
        "b" : {
          "x" : 705,
          "y" : 786
        },
        "c" : {
          "x" : 697,
          "y" : 788
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 697,
          "y" : 788
        }
      }
    }, {
      "edgeId" : 120,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 718,
          "y" : 750
        },
        "to" : {
          "x" : 714,
          "y" : 722
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 115,
    "reactomeId" : 936714,
    "displayName" : "2OBUTA",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 714,
      "y" : 856
    },
    "minX" : 672,
    "maxX" : 758,
    "minY" : 813,
    "maxY" : 874,
    "prop" : {
      "x" : 672,
      "y" : 839,
      "width" : 85,
      "height" : 35
    },
    "textPosition" : {
      "x" : 686,
      "y" : 846
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 752,
          "y" : 844
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 752,
          "y" : 844
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 109,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 698,
          "y" : 836
        },
        "to" : {
          "x" : 675,
          "y" : 813
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 690,
          "y" : 834
        },
        "b" : {
          "x" : 698,
          "y" : 836
        },
        "c" : {
          "x" : 696,
          "y" : 828
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 696,
          "y" : 828
        }
      }
    } ]
  }, {
    "id" : 117,
    "reactomeId" : 1625212,
    "displayName" : "PXLP-K212-CTH tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 648,
      "y" : 899
    },
    "minX" : 599,
    "maxX" : 703,
    "minY" : 821,
    "maxY" : 919,
    "prop" : {
      "x" : 599,
      "y" : 879,
      "width" : 98,
      "height" : 40
    },
    "textPosition" : {
      "x" : 602,
      "y" : 884
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 697,
          "y" : 879
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 697,
          "y" : 879
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 109,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 648,
          "y" : 876
        },
        "to" : {
          "x" : 649,
          "y" : 829
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 649,
          "y" : 825
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 649,
          "y" : 825
        }
      }
    } ]
  }, {
    "id" : 122,
    "reactomeId" : 29432,
    "displayName" : "L-Ala",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 658,
      "y" : 661
    },
    "minX" : 635,
    "maxX" : 723,
    "minY" : 644,
    "maxY" : 676,
    "prop" : {
      "x" : 635,
      "y" : 646,
      "width" : 47,
      "height" : 30
    },
    "textPosition" : {
      "x" : 640,
      "y" : 650
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 677,
          "y" : 651
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 677,
          "y" : 651
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 120,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 685,
          "y" : 654
        },
        "to" : {
          "x" : 723,
          "y" : 644
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 691,
          "y" : 648
        },
        "b" : {
          "x" : 685,
          "y" : 654
        },
        "c" : {
          "x" : 693,
          "y" : 656
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 693,
          "y" : 656
        }
      }
    } ]
  }, {
    "id" : 123,
    "reactomeId" : 5357660,
    "displayName" : "selanide",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 741,
      "y" : 590
    },
    "minX" : 153,
    "maxX" : 904,
    "minY" : 545,
    "maxY" : 1282,
    "prop" : {
      "x" : 710,
      "y" : 576,
      "width" : 62,
      "height" : 28
    },
    "textPosition" : {
      "x" : 710,
      "y" : 579
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 767,
          "y" : 581
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 767,
          "y" : 581
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 261,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 755,
          "y" : 607
        },
        "to" : {
          "x" : 821,
          "y" : 666
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 763,
          "y" : 609
        },
        "b" : {
          "x" : 755,
          "y" : 607
        },
        "c" : {
          "x" : 757,
          "y" : 615
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 757,
          "y" : 615
        }
      }
    }, {
      "edgeId" : 133,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 733,
          "y" : 573
        },
        "to" : {
          "x" : 716,
          "y" : 545
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 726,
          "y" : 569
        },
        "b" : {
          "x" : 733,
          "y" : 573
        },
        "c" : {
          "x" : 733,
          "y" : 565
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 733,
          "y" : 565
        }
      }
    }, {
      "edgeId" : 138,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 744,
          "y" : 573
        },
        "to" : {
          "x" : 751,
          "y" : 550
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 418,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 707,
          "y" : 590
        },
        "to" : {
          "x" : 155,
          "y" : 594
        }
      }, {
        "from" : {
          "x" : 155,
          "y" : 594
        },
        "to" : {
          "x" : 153,
          "y" : 1282
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 120,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 736,
          "y" : 607
        },
        "to" : {
          "x" : 723,
          "y" : 644
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 737,
          "y" : 615
        },
        "b" : {
          "x" : 736,
          "y" : 607
        },
        "c" : {
          "x" : 730,
          "y" : 612
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 730,
          "y" : 612
        }
      }
    }, {
      "edgeId" : 250,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 768,
          "y" : 607
        },
        "to" : {
          "x" : 904,
          "y" : 672
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 776,
          "y" : 606
        },
        "b" : {
          "x" : 768,
          "y" : 607
        },
        "c" : {
          "x" : 773,
          "y" : 614
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 773,
          "y" : 614
        }
      }
    } ]
  }, {
    "id" : 125,
    "reactomeId" : 5359018,
    "displayName" : "PXLP-K259-SCLY dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 558,
      "y" : 688
    },
    "minX" : 514,
    "maxX" : 705,
    "minY" : 661,
    "maxY" : 710,
    "prop" : {
      "x" : 514,
      "y" : 667,
      "width" : 88,
      "height" : 43
    },
    "textPosition" : {
      "x" : 520,
      "y" : 675
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 602,
          "y" : 667
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 602,
          "y" : 667
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 120,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 605,
          "y" : 686
        },
        "to" : {
          "x" : 697,
          "y" : 683
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 701,
          "y" : 682
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 701,
          "y" : 682
        }
      }
    } ]
  }, {
    "id" : 129,
    "reactomeId" : 5357710,
    "displayName" : "MeSec",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 851,
      "y" : 195
    },
    "minX" : 804,
    "maxX" : 879,
    "minY" : 179,
    "maxY" : 235,
    "prop" : {
      "x" : 825,
      "y" : 180,
      "width" : 53,
      "height" : 30
    },
    "textPosition" : {
      "x" : 827,
      "y" : 184
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 873,
          "y" : 185
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 873,
          "y" : 185
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 127,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 833,
          "y" : 213
        },
        "to" : {
          "x" : 804,
          "y" : 235
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 134,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 632,
      "y" : 450
    },
    "minX" : 611,
    "maxX" : 716,
    "minY" : 434,
    "maxY" : 472,
    "prop" : {
      "x" : 611,
      "y" : 435,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 615,
      "y" : 439
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 649,
          "y" : 440
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 649,
          "y" : 440
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 133,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 657,
          "y" : 455
        },
        "to" : {
          "x" : 716,
          "y" : 472
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 135,
    "reactomeId" : 5359061,
    "displayName" : "MeOH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 623,
      "y" : 547
    },
    "minX" : 597,
    "maxX" : 716,
    "minY" : 531,
    "maxY" : 562,
    "prop" : {
      "x" : 597,
      "y" : 532,
      "width" : 52,
      "height" : 30
    },
    "textPosition" : {
      "x" : 601,
      "y" : 536
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 644,
          "y" : 537
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 644,
          "y" : 537
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 133,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 652,
          "y" : 546
        },
        "to" : {
          "x" : 716,
          "y" : 545
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 659,
          "y" : 542
        },
        "b" : {
          "x" : 652,
          "y" : 546
        },
        "c" : {
          "x" : 659,
          "y" : 550
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 659,
          "y" : 550
        }
      }
    } ]
  }, {
    "id" : 136,
    "reactomeId" : 5357666,
    "displayName" : "MSDM",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 641,
      "y" : 502
    },
    "minX" : 619,
    "maxX" : 708,
    "minY" : 491,
    "maxY" : 513,
    "prop" : {
      "x" : 619,
      "y" : 491,
      "width" : 44,
      "height" : 22
    },
    "textPosition" : {
      "x" : 623,
      "y" : 485
    },
    "connectors" : [ {
      "edgeId" : 133,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 666,
          "y" : 502
        },
        "to" : {
          "x" : 700,
          "y" : 503
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 704,
          "y" : 504
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 704,
          "y" : 504
        }
      }
    } ]
  }, {
    "id" : 907,
    "reactomeId" : 9939356,
    "displayName" : "unknown selenosugar synthase",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1313,
      "y" : 548
    },
    "minX" : 1274,
    "maxX" : 1353,
    "minY" : 524,
    "maxY" : 604,
    "prop" : {
      "x" : 1274,
      "y" : 524,
      "width" : 79,
      "height" : 49
    },
    "textPosition" : {
      "x" : 1277,
      "y" : 517
    },
    "connectors" : [ {
      "edgeId" : 243,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1314,
          "y" : 576
        },
        "to" : {
          "x" : 1316,
          "y" : 596
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1316,
          "y" : 600
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1316,
          "y" : 600
        }
      }
    } ]
  }, {
    "id" : 139,
    "reactomeId" : 71284,
    "displayName" : "AdoMet",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 819,
      "y" : 563
    },
    "minX" : 751,
    "maxX" : 911,
    "minY" : 471,
    "maxY" : 578,
    "prop" : {
      "x" : 789,
      "y" : 548,
      "width" : 61,
      "height" : 30
    },
    "textPosition" : {
      "x" : 792,
      "y" : 552
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 845,
          "y" : 553
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 845,
          "y" : 553
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 786,
          "y" : 557
        },
        "to" : {
          "x" : 751,
          "y" : 550
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 213,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 834,
          "y" : 545
        },
        "to" : {
          "x" : 911,
          "y" : 471
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 140,
    "reactomeId" : 71285,
    "displayName" : "AdoHcy",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 803,
      "y" : 468
    },
    "minX" : 751,
    "maxX" : 835,
    "minY" : 452,
    "maxY" : 483,
    "prop" : {
      "x" : 773,
      "y" : 453,
      "width" : 61,
      "height" : 30
    },
    "textPosition" : {
      "x" : 776,
      "y" : 457
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 829,
          "y" : 458
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 829,
          "y" : 458
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 138,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 770,
          "y" : 473
        },
        "to" : {
          "x" : 751,
          "y" : 478
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 764,
          "y" : 479
        },
        "b" : {
          "x" : 770,
          "y" : 473
        },
        "c" : {
          "x" : 762,
          "y" : 471
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 762,
          "y" : 471
        }
      }
    } ]
  }, {
    "id" : 141,
    "reactomeId" : 5359039,
    "displayName" : "HSeMT",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 818,
      "y" : 510
    },
    "minX" : 759,
    "maxX" : 843,
    "minY" : 499,
    "maxY" : 521,
    "prop" : {
      "x" : 794,
      "y" : 499,
      "width" : 49,
      "height" : 22
    },
    "textPosition" : {
      "x" : 797,
      "y" : 493
    },
    "connectors" : [ {
      "edgeId" : 138,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 791,
          "y" : 510
        },
        "to" : {
          "x" : 767,
          "y" : 510
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 763,
          "y" : 510
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 763,
          "y" : 510
        }
      }
    } ]
  }, {
    "id" : 405,
    "reactomeId" : 8959518,
    "displayName" : "SELP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 363,
      "y" : 1281
    },
    "minX" : 249,
    "maxX" : 424,
    "minY" : 1265,
    "maxY" : 1296,
    "prop" : {
      "x" : 342,
      "y" : 1266,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 344,
      "y" : 1270
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 380,
          "y" : 1271
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 380,
          "y" : 1271
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 340,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 388,
          "y" : 1286
        },
        "to" : {
          "x" : 424,
          "y" : 1296
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 418,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 339,
          "y" : 1281
        },
        "to" : {
          "x" : 249,
          "y" : 1282
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 332,
          "y" : 1285
        },
        "b" : {
          "x" : 339,
          "y" : 1281
        },
        "c" : {
          "x" : 332,
          "y" : 1277
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 332,
          "y" : 1277
        }
      }
    } ]
  }, {
    "id" : 406,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 470,
      "y" : 1282
    },
    "minX" : 424,
    "maxX" : 493,
    "minY" : 1266,
    "maxY" : 1297,
    "prop" : {
      "x" : 449,
      "y" : 1267,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 453,
      "y" : 1271
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 487,
          "y" : 1272
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 487,
          "y" : 1272
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 340,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 446,
          "y" : 1288
        },
        "to" : {
          "x" : 424,
          "y" : 1296
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 666,
    "reactomeId" : 31633,
    "displayName" : "NH4+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 730,
      "y" : 351
    },
    "minX" : 656,
    "maxX" : 807,
    "minY" : 314,
    "maxY" : 367,
    "prop" : {
      "x" : 704,
      "y" : 336,
      "width" : 53,
      "height" : 31
    },
    "textPosition" : {
      "x" : 708,
      "y" : 341
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 752,
          "y" : 341
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 752,
          "y" : 341
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 4,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 701,
          "y" : 339
        },
        "to" : {
          "x" : 656,
          "y" : 318
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 693,
          "y" : 340
        },
        "b" : {
          "x" : 701,
          "y" : 339
        },
        "c" : {
          "x" : 696,
          "y" : 332
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 696,
          "y" : 332
        }
      }
    }, {
      "edgeId" : 127,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 760,
          "y" : 338
        },
        "to" : {
          "x" : 807,
          "y" : 314
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 764,
          "y" : 331
        },
        "b" : {
          "x" : 760,
          "y" : 338
        },
        "c" : {
          "x" : 768,
          "y" : 338
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 768,
          "y" : 338
        }
      }
    } ]
  }, {
    "id" : 931,
    "reactomeId" : 9939359,
    "displayName" : "unknown selenosugar methylase",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1208,
      "y" : 538
    },
    "minX" : 1113,
    "maxX" : 1249,
    "minY" : 513,
    "maxY" : 564,
    "prop" : {
      "x" : 1167,
      "y" : 513,
      "width" : 82,
      "height" : 51
    },
    "textPosition" : {
      "x" : 1167,
      "y" : 514
    },
    "connectors" : [ {
      "edgeId" : 234,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1164,
          "y" : 537
        },
        "to" : {
          "x" : 1121,
          "y" : 537
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1117,
          "y" : 537
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1117,
          "y" : 537
        }
      }
    } ]
  }, {
    "id" : 419,
    "reactomeId" : 113592,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 110,
      "y" : 1324
    },
    "minX" : 90,
    "maxX" : 153,
    "minY" : 1282,
    "maxY" : 1339,
    "prop" : {
      "x" : 90,
      "y" : 1309,
      "width" : 40,
      "height" : 30
    },
    "textPosition" : {
      "x" : 94,
      "y" : 1313
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 125,
          "y" : 1314
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 125,
          "y" : 1314
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 418,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 125,
          "y" : 1306
        },
        "to" : {
          "x" : 153,
          "y" : 1282
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 420,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 97,
      "y" : 1247
    },
    "minX" : 76,
    "maxX" : 153,
    "minY" : 1231,
    "maxY" : 1282,
    "prop" : {
      "x" : 76,
      "y" : 1232,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 80,
      "y" : 1236
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 114,
          "y" : 1237
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 114,
          "y" : 1237
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 418,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 122,
          "y" : 1260
        },
        "to" : {
          "x" : 153,
          "y" : 1282
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 421,
    "reactomeId" : 8959500,
    "displayName" : "SEPHS2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 209,
      "y" : 1233
    },
    "minX" : 183,
    "maxX" : 241,
    "minY" : 1216,
    "maxY" : 1274,
    "prop" : {
      "x" : 183,
      "y" : 1222,
      "width" : 52,
      "height" : 22
    },
    "textPosition" : {
      "x" : 184,
      "y" : 1216
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 235,
          "y" : 1222
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 235,
          "y" : 1222
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 418,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 209,
          "y" : 1247
        },
        "to" : {
          "x" : 210,
          "y" : 1266
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 210,
          "y" : 1270
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 210,
          "y" : 1270
        }
      }
    } ]
  }, {
    "id" : 426,
    "reactomeId" : 76577,
    "displayName" : "AMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 299,
      "y" : 1325
    },
    "minX" : 249,
    "maxX" : 321,
    "minY" : 1282,
    "maxY" : 1340,
    "prop" : {
      "x" : 278,
      "y" : 1310,
      "width" : 42,
      "height" : 30
    },
    "textPosition" : {
      "x" : 282,
      "y" : 1314
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 315,
          "y" : 1315
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 315,
          "y" : 1315
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 418,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 281,
          "y" : 1307
        },
        "to" : {
          "x" : 249,
          "y" : 1282
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 273,
          "y" : 1306
        },
        "b" : {
          "x" : 281,
          "y" : 1307
        },
        "c" : {
          "x" : 278,
          "y" : 1300
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 278,
          "y" : 1300
        }
      }
    } ]
  }, {
    "id" : 428,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 274,
      "y" : 1363
    },
    "minX" : 249,
    "maxX" : 291,
    "minY" : 1282,
    "maxY" : 1378,
    "prop" : {
      "x" : 259,
      "y" : 1348,
      "width" : 31,
      "height" : 30
    },
    "textPosition" : {
      "x" : 265,
      "y" : 1352
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 285,
          "y" : 1353
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 285,
          "y" : 1353
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 418,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 269,
          "y" : 1345
        },
        "to" : {
          "x" : 249,
          "y" : 1282
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 263,
          "y" : 1340
        },
        "b" : {
          "x" : 269,
          "y" : 1345
        },
        "c" : {
          "x" : 271,
          "y" : 1337
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 271,
          "y" : 1337
        }
      }
    } ]
  }, {
    "id" : 430,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 235,
      "y" : 1339
    },
    "minX" : 217,
    "maxX" : 254,
    "minY" : 1282,
    "maxY" : 1354,
    "prop" : {
      "x" : 217,
      "y" : 1324,
      "width" : 36,
      "height" : 30
    },
    "textPosition" : {
      "x" : 221,
      "y" : 1328
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 248,
          "y" : 1329
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 248,
          "y" : 1329
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 418,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 238,
          "y" : 1321
        },
        "to" : {
          "x" : 249,
          "y" : 1282
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 237,
            "y" : 1295
          },
          "b" : {
            "x" : 249,
            "y" : 1307
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 243,
            "y" : 1301
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 236,
          "y" : 1313
        },
        "b" : {
          "x" : 238,
          "y" : 1321
        },
        "c" : {
          "x" : 244,
          "y" : 1315
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 244,
          "y" : 1315
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 433,
    "reactomeId" : 29372,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 357,
      "y" : 1385
    },
    "minX" : 342,
    "maxX" : 426,
    "minY" : 1368,
    "maxY" : 1400,
    "prop" : {
      "x" : 342,
      "y" : 1370,
      "width" : 31,
      "height" : 30
    },
    "textPosition" : {
      "x" : 348,
      "y" : 1374
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 368,
          "y" : 1375
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 368,
          "y" : 1375
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 340,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 376,
          "y" : 1381
        },
        "to" : {
          "x" : 426,
          "y" : 1368
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 395,
            "y" : 1368
          },
          "b" : {
            "x" : 407,
            "y" : 1380
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 401,
            "y" : 1374
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 382,
          "y" : 1375
        },
        "b" : {
          "x" : 376,
          "y" : 1381
        },
        "c" : {
          "x" : 384,
          "y" : 1383
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 384,
          "y" : 1383
        }
      }
    } ]
  }, {
    "id" : 955,
    "reactomeId" : 9939360,
    "displayName" : "unknown selenosugar hydrolase",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1029,
      "y" : 355
    },
    "minX" : 988,
    "maxX" : 1070,
    "minY" : 330,
    "maxY" : 408,
    "prop" : {
      "x" : 988,
      "y" : 330,
      "width" : 82,
      "height" : 51
    },
    "textPosition" : {
      "x" : 988,
      "y" : 331
    },
    "connectors" : [ {
      "edgeId" : 209,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1029,
          "y" : 384
        },
        "to" : {
          "x" : 1030,
          "y" : 400
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1030,
          "y" : 404
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1030,
          "y" : 404
        }
      }
    } ]
  }, {
    "id" : 191,
    "reactomeId" : 29364,
    "displayName" : "NADPH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 889,
      "y" : 236
    },
    "minX" : 860,
    "maxX" : 950,
    "minY" : 220,
    "maxY" : 262,
    "prop" : {
      "x" : 860,
      "y" : 221,
      "width" : 59,
      "height" : 30
    },
    "textPosition" : {
      "x" : 864,
      "y" : 225
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 914,
          "y" : 226
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 914,
          "y" : 226
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 190,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 922,
          "y" : 248
        },
        "to" : {
          "x" : 950,
          "y" : 262
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 192,
    "reactomeId" : 5357663,
    "displayName" : "MeSeOH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1007,
      "y" : 224
    },
    "minX" : 950,
    "maxX" : 1088,
    "minY" : 200,
    "maxY" : 262,
    "prop" : {
      "x" : 975,
      "y" : 209,
      "width" : 65,
      "height" : 30
    },
    "textPosition" : {
      "x" : 977,
      "y" : 213
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1035,
          "y" : 214
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1035,
          "y" : 214
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 197,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1043,
          "y" : 214
        },
        "to" : {
          "x" : 1088,
          "y" : 200
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1048,
          "y" : 208
        },
        "b" : {
          "x" : 1043,
          "y" : 214
        },
        "c" : {
          "x" : 1051,
          "y" : 216
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1051,
          "y" : 216
        }
      }
    }, {
      "edgeId" : 190,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 984,
          "y" : 242
        },
        "to" : {
          "x" : 950,
          "y" : 262
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 193,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 947,
      "y" : 194
    },
    "minX" : 929,
    "maxX" : 966,
    "minY" : 178,
    "maxY" : 262,
    "prop" : {
      "x" : 929,
      "y" : 179,
      "width" : 36,
      "height" : 30
    },
    "textPosition" : {
      "x" : 933,
      "y" : 183
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 960,
          "y" : 184
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 960,
          "y" : 184
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 190,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 947,
          "y" : 212
        },
        "to" : {
          "x" : 950,
          "y" : 262
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 194,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 957,
      "y" : 388
    },
    "minX" : 871,
    "maxX" : 980,
    "minY" : 372,
    "maxY" : 403,
    "prop" : {
      "x" : 936,
      "y" : 373,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 940,
      "y" : 377
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 974,
          "y" : 378
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 974,
          "y" : 378
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 190,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 933,
          "y" : 388
        },
        "to" : {
          "x" : 871,
          "y" : 391
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 926,
          "y" : 392
        },
        "b" : {
          "x" : 933,
          "y" : 388
        },
        "c" : {
          "x" : 926,
          "y" : 384
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 926,
          "y" : 384
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 195,
    "reactomeId" : 29366,
    "displayName" : "NADP+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 881,
      "y" : 346
    },
    "minX" : 851,
    "maxX" : 912,
    "minY" : 330,
    "maxY" : 391,
    "prop" : {
      "x" : 851,
      "y" : 331,
      "width" : 60,
      "height" : 30
    },
    "textPosition" : {
      "x" : 855,
      "y" : 335
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 906,
          "y" : 336
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 906,
          "y" : 336
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 190,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 877,
          "y" : 364
        },
        "to" : {
          "x" : 871,
          "y" : 391
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 879,
          "y" : 372
        },
        "b" : {
          "x" : 877,
          "y" : 364
        },
        "c" : {
          "x" : 872,
          "y" : 370
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 872,
          "y" : 370
        }
      }
    } ]
  }, {
    "id" : 196,
    "reactomeId" : 73532,
    "displayName" : "TNXRD1:FAD dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 882,
      "y" : 298
    },
    "minX" : 844,
    "maxX" : 944,
    "minY" : 272,
    "maxY" : 350,
    "prop" : {
      "x" : 844,
      "y" : 278,
      "width" : 76,
      "height" : 40
    },
    "textPosition" : {
      "x" : 846,
      "y" : 283
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 920,
          "y" : 278
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 920,
          "y" : 278
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 190,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 906,
          "y" : 321
        },
        "to" : {
          "x" : 937,
          "y" : 344
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 940,
          "y" : 346
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 940,
          "y" : 346
        }
      }
    } ]
  }, {
    "id" : 198,
    "reactomeId" : 5357694,
    "displayName" : "MeSeO2H",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1271,
      "y" : 232
    },
    "minX" : 1167,
    "maxX" : 1309,
    "minY" : 201,
    "maxY" : 460,
    "prop" : {
      "x" : 1235,
      "y" : 217,
      "width" : 73,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1237,
      "y" : 221
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1303,
          "y" : 222
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1303,
          "y" : 222
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 197,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1232,
          "y" : 221
        },
        "to" : {
          "x" : 1167,
          "y" : 201
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 229,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1271,
          "y" : 250
        },
        "to" : {
          "x" : 1272,
          "y" : 460
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1275,
          "y" : 257
        },
        "b" : {
          "x" : 1271,
          "y" : 250
        },
        "c" : {
          "x" : 1267,
          "y" : 257
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1267,
          "y" : 257
        }
      }
    } ]
  }, {
    "id" : 199,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1102,
      "y" : 249
    },
    "minX" : 1081,
    "maxX" : 1125,
    "minY" : 200,
    "maxY" : 264,
    "prop" : {
      "x" : 1081,
      "y" : 234,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1085,
      "y" : 238
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1119,
          "y" : 239
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1119,
          "y" : 239
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 197,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1097,
          "y" : 231
        },
        "to" : {
          "x" : 1088,
          "y" : 200
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1091,
          "y" : 225
        },
        "b" : {
          "x" : 1097,
          "y" : 231
        },
        "c" : {
          "x" : 1099,
          "y" : 223
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1099,
          "y" : 223
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 201,
    "reactomeId" : 29366,
    "displayName" : "NADP+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1010,
      "y" : 163
    },
    "minX" : 980,
    "maxX" : 1088,
    "minY" : 147,
    "maxY" : 200,
    "prop" : {
      "x" : 980,
      "y" : 148,
      "width" : 60,
      "height" : 30
    },
    "textPosition" : {
      "x" : 984,
      "y" : 152
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1035,
          "y" : 153
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1035,
          "y" : 153
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 197,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1043,
          "y" : 177
        },
        "to" : {
          "x" : 1088,
          "y" : 200
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1051,
          "y" : 177
        },
        "b" : {
          "x" : 1043,
          "y" : 177
        },
        "c" : {
          "x" : 1047,
          "y" : 184
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1047,
          "y" : 184
        }
      }
    } ]
  }, {
    "id" : 202,
    "reactomeId" : 29364,
    "displayName" : "NADPH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1236,
      "y" : 149
    },
    "minX" : 1167,
    "maxX" : 1267,
    "minY" : 133,
    "maxY" : 201,
    "prop" : {
      "x" : 1207,
      "y" : 134,
      "width" : 59,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1211,
      "y" : 138
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1261,
          "y" : 139
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1261,
          "y" : 139
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 197,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1216,
          "y" : 167
        },
        "to" : {
          "x" : 1167,
          "y" : 201
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 714,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 220,
      "y" : 634
    },
    "minX" : 202,
    "maxX" : 278,
    "minY" : 608,
    "maxY" : 649,
    "prop" : {
      "x" : 202,
      "y" : 619,
      "width" : 36,
      "height" : 30
    },
    "textPosition" : {
      "x" : 206,
      "y" : 623
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 233,
          "y" : 624
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 233,
          "y" : 624
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 20,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 241,
          "y" : 625
        },
        "to" : {
          "x" : 278,
          "y" : 608
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 246,
          "y" : 618
        },
        "b" : {
          "x" : 241,
          "y" : 625
        },
        "c" : {
          "x" : 249,
          "y" : 626
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 249,
          "y" : 626
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 205,
    "reactomeId" : 73532,
    "displayName" : "TNXRD1:FAD dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1127,
      "y" : 143
    },
    "minX" : 1089,
    "maxX" : 1172,
    "minY" : 119,
    "maxY" : 192,
    "prop" : {
      "x" : 1089,
      "y" : 125,
      "width" : 77,
      "height" : 37
    },
    "textPosition" : {
      "x" : 1092,
      "y" : 127
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1166,
          "y" : 125
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1166,
          "y" : 125
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 197,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1126,
          "y" : 165
        },
        "to" : {
          "x" : 1126,
          "y" : 184
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1126,
          "y" : 188
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1126,
          "y" : 188
        }
      }
    } ]
  }, {
    "id" : 206,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1171,
      "y" : 273
    },
    "minX" : 1153,
    "maxX" : 1190,
    "minY" : 201,
    "maxY" : 288,
    "prop" : {
      "x" : 1153,
      "y" : 258,
      "width" : 36,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1157,
      "y" : 262
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1184,
          "y" : 263
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1184,
          "y" : 263
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 197,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1170,
          "y" : 255
        },
        "to" : {
          "x" : 1167,
          "y" : 201
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 210,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1099,
      "y" : 382
    },
    "minX" : 1072,
    "maxX" : 1122,
    "minY" : 366,
    "maxY" : 417,
    "prop" : {
      "x" : 1078,
      "y" : 367,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1082,
      "y" : 371
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1116,
          "y" : 372
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1116,
          "y" : 372
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 209,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1087,
          "y" : 400
        },
        "to" : {
          "x" : 1072,
          "y" : 417
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 211,
    "reactomeId" : 5357685,
    "displayName" : "MeSebGalNac",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1106,
      "y" : 462
    },
    "minX" : 1058,
    "maxX" : 1155,
    "minY" : 417,
    "maxY" : 518,
    "prop" : {
      "x" : 1058,
      "y" : 447,
      "width" : 96,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1059,
      "y" : 451
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1149,
          "y" : 452
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1149,
          "y" : 452
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 209,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1094,
          "y" : 444
        },
        "to" : {
          "x" : 1072,
          "y" : 417
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 229,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 234,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1105,
          "y" : 480
        },
        "to" : {
          "x" : 1105,
          "y" : 518
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1109,
          "y" : 487
        },
        "b" : {
          "x" : 1105,
          "y" : 480
        },
        "c" : {
          "x" : 1101,
          "y" : 487
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1101,
          "y" : 487
        }
      }
    } ]
  }, {
    "id" : 212,
    "reactomeId" : 5357725,
    "displayName" : "bGalNAc",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 956,
      "y" : 446
    },
    "minX" : 923,
    "maxX" : 991,
    "minY" : 415,
    "maxY" : 461,
    "prop" : {
      "x" : 923,
      "y" : 431,
      "width" : 67,
      "height" : 30
    },
    "textPosition" : {
      "x" : 926,
      "y" : 435
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 985,
          "y" : 436
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 985,
          "y" : 436
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 209,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 965,
          "y" : 428
        },
        "to" : {
          "x" : 975,
          "y" : 415
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 966,
          "y" : 420
        },
        "b" : {
          "x" : 965,
          "y" : 428
        },
        "c" : {
          "x" : 972,
          "y" : 425
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 972,
          "y" : 425
        }
      }
    } ]
  }, {
    "id" : 214,
    "reactomeId" : 5357673,
    "displayName" : "Me2Se",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1067,
      "y" : 634
    },
    "minX" : 970,
    "maxX" : 1143,
    "minY" : 577,
    "maxY" : 662,
    "prop" : {
      "x" : 1040,
      "y" : 619,
      "width" : 55,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1042,
      "y" : 623
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1090,
          "y" : 624
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1090,
          "y" : 624
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 213,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1041,
          "y" : 616
        },
        "to" : {
          "x" : 970,
          "y" : 577
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1033,
          "y" : 616
        },
        "b" : {
          "x" : 1041,
          "y" : 616
        },
        "c" : {
          "x" : 1037,
          "y" : 609
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1037,
          "y" : 609
        }
      }
    }, {
      "edgeId" : 220,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1098,
          "y" : 644
        },
        "to" : {
          "x" : 1143,
          "y" : 662
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 215,
    "reactomeId" : 5359068,
    "displayName" : "MeSeHMT",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 918,
      "y" : 526
    },
    "minX" : 885,
    "maxX" : 964,
    "minY" : 493,
    "maxY" : 537,
    "prop" : {
      "x" : 885,
      "y" : 515,
      "width" : 66,
      "height" : 22
    },
    "textPosition" : {
      "x" : 887,
      "y" : 509
    },
    "connectors" : [ {
      "edgeId" : 213,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 934,
          "y" : 512
        },
        "to" : {
          "x" : 956,
          "y" : 499
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 960,
          "y" : 497
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 960,
          "y" : 497
        }
      }
    } ]
  }, {
    "id" : 218,
    "reactomeId" : 71285,
    "displayName" : "AdoHcy",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 881,
      "y" : 598
    },
    "minX" : 851,
    "maxX" : 970,
    "minY" : 577,
    "maxY" : 613,
    "prop" : {
      "x" : 851,
      "y" : 583,
      "width" : 61,
      "height" : 30
    },
    "textPosition" : {
      "x" : 854,
      "y" : 587
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 907,
          "y" : 588
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 907,
          "y" : 588
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 213,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 915,
          "y" : 590
        },
        "to" : {
          "x" : 970,
          "y" : 577
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 921,
          "y" : 585
        },
        "b" : {
          "x" : 915,
          "y" : 590
        },
        "c" : {
          "x" : 923,
          "y" : 592
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 923,
          "y" : 592
        }
      }
    } ]
  }, {
    "id" : 221,
    "reactomeId" : 5357659,
    "displayName" : "Me3Se+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1313,
      "y" : 722
    },
    "minX" : 1239,
    "maxX" : 1347,
    "minY" : 664,
    "maxY" : 737,
    "prop" : {
      "x" : 1281,
      "y" : 707,
      "width" : 65,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1283,
      "y" : 711
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1341,
          "y" : 712
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1341,
          "y" : 712
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 220,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1293,
          "y" : 704
        },
        "to" : {
          "x" : 1239,
          "y" : 664
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1285,
          "y" : 703
        },
        "b" : {
          "x" : 1293,
          "y" : 704
        },
        "c" : {
          "x" : 1290,
          "y" : 697
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1290,
          "y" : 697
        }
      }
    } ]
  }, {
    "id" : 222,
    "reactomeId" : 5357693,
    "displayName" : "INMT",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1187,
      "y" : 714
    },
    "minX" : 1168,
    "maxX" : 1213,
    "minY" : 671,
    "maxY" : 725,
    "prop" : {
      "x" : 1168,
      "y" : 703,
      "width" : 39,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1169,
      "y" : 703
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1207,
          "y" : 703
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1207,
          "y" : 703
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 220,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1186,
          "y" : 700
        },
        "to" : {
          "x" : 1185,
          "y" : 679
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1185,
          "y" : 675
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1185,
          "y" : 675
        }
      }
    } ]
  }, {
    "id" : 226,
    "reactomeId" : 71285,
    "displayName" : "AdoHcy",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1321,
      "y" : 667
    },
    "minX" : 1239,
    "maxX" : 1353,
    "minY" : 651,
    "maxY" : 682,
    "prop" : {
      "x" : 1291,
      "y" : 652,
      "width" : 61,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1294,
      "y" : 656
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1347,
          "y" : 657
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1347,
          "y" : 657
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 220,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1288,
          "y" : 665
        },
        "to" : {
          "x" : 1239,
          "y" : 664
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1281,
          "y" : 669
        },
        "b" : {
          "x" : 1288,
          "y" : 665
        },
        "c" : {
          "x" : 1281,
          "y" : 661
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1281,
          "y" : 661
        }
      }
    } ]
  }, {
    "id" : 227,
    "reactomeId" : 71284,
    "displayName" : "AdoMet",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1076,
      "y" : 691
    },
    "minX" : 1046,
    "maxX" : 1143,
    "minY" : 662,
    "maxY" : 706,
    "prop" : {
      "x" : 1046,
      "y" : 676,
      "width" : 61,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1049,
      "y" : 680
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1102,
          "y" : 681
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1102,
          "y" : 681
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 220,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1110,
          "y" : 677
        },
        "to" : {
          "x" : 1143,
          "y" : 662
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 230,
    "reactomeId" : 5357647,
    "displayName" : "2-acetamidoglucal",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1370,
      "y" : 471
    },
    "minX" : 1272,
    "maxX" : 1434,
    "minY" : 455,
    "maxY" : 486,
    "prop" : {
      "x" : 1308,
      "y" : 456,
      "width" : 125,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1309,
      "y" : 460
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1428,
          "y" : 461
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1428,
          "y" : 461
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 229,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1305,
          "y" : 463
        },
        "to" : {
          "x" : 1272,
          "y" : 460
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1298,
          "y" : 466
        },
        "b" : {
          "x" : 1305,
          "y" : 463
        },
        "c" : {
          "x" : 1298,
          "y" : 458
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1298,
          "y" : 458
        }
      }
    } ]
  }, {
    "id" : 235,
    "reactomeId" : 5357683,
    "displayName" : "GSSebGalNac",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1213,
      "y" : 606
    },
    "minX" : 1105,
    "maxX" : 1261,
    "minY" : 562,
    "maxY" : 621,
    "prop" : {
      "x" : 1166,
      "y" : 591,
      "width" : 94,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1166,
      "y" : 595
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1255,
          "y" : 596
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1255,
          "y" : 596
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 234,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1176,
          "y" : 588
        },
        "to" : {
          "x" : 1105,
          "y" : 562
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 243,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 236,
    "reactomeId" : 29450,
    "displayName" : "GSH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1165,
      "y" : 493
    },
    "minX" : 1105,
    "maxX" : 1187,
    "minY" : 477,
    "maxY" : 518,
    "prop" : {
      "x" : 1145,
      "y" : 478,
      "width" : 41,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1148,
      "y" : 482
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1181,
          "y" : 483
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1181,
          "y" : 483
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 234,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1142,
          "y" : 501
        },
        "to" : {
          "x" : 1105,
          "y" : 518
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1137,
          "y" : 508
        },
        "b" : {
          "x" : 1142,
          "y" : 501
        },
        "c" : {
          "x" : 1134,
          "y" : 500
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1134,
          "y" : 500
        }
      }
    } ]
  }, {
    "id" : 238,
    "reactomeId" : 71284,
    "displayName" : "AdoMet",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1047,
      "y" : 575
    },
    "minX" : 1017,
    "maxX" : 1105,
    "minY" : 559,
    "maxY" : 590,
    "prop" : {
      "x" : 1017,
      "y" : 560,
      "width" : 61,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1020,
      "y" : 564
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1073,
          "y" : 565
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1073,
          "y" : 565
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 234,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1081,
          "y" : 568
        },
        "to" : {
          "x" : 1105,
          "y" : 562
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 240,
    "reactomeId" : 71285,
    "displayName" : "AdoHcy",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1034,
      "y" : 489
    },
    "minX" : 1004,
    "maxX" : 1105,
    "minY" : 473,
    "maxY" : 518,
    "prop" : {
      "x" : 1004,
      "y" : 474,
      "width" : 61,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1007,
      "y" : 478
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1060,
          "y" : 479
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1060,
          "y" : 479
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 234,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1068,
          "y" : 501
        },
        "to" : {
          "x" : 1105,
          "y" : 518
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1076,
          "y" : 500
        },
        "b" : {
          "x" : 1068,
          "y" : 501
        },
        "c" : {
          "x" : 1073,
          "y" : 508
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1073,
          "y" : 508
        }
      }
    } ]
  }, {
    "id" : 244,
    "reactomeId" : 5357664,
    "displayName" : "GSSeH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1399,
      "y" : 661
    },
    "minX" : 836,
    "maxX" : 1579,
    "minY" : 613,
    "maxY" : 942,
    "prop" : {
      "x" : 1372,
      "y" : 646,
      "width" : 54,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1374,
      "y" : 650
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1421,
          "y" : 651
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1421,
          "y" : 651
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 261,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1429,
          "y" : 661
        },
        "to" : {
          "x" : 1577,
          "y" : 661
        }
      }, {
        "from" : {
          "x" : 1577,
          "y" : 661
        },
        "to" : {
          "x" : 1579,
          "y" : 942
        }
      }, {
        "from" : {
          "x" : 1579,
          "y" : 942
        },
        "to" : {
          "x" : 839,
          "y" : 931
        }
      }, {
        "from" : {
          "x" : 839,
          "y" : 931
        },
        "to" : {
          "x" : 836,
          "y" : 747
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 276,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1410,
          "y" : 679
        },
        "to" : {
          "x" : 1464,
          "y" : 744
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1418,
          "y" : 682
        },
        "b" : {
          "x" : 1410,
          "y" : 679
        },
        "c" : {
          "x" : 1411,
          "y" : 687
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1411,
          "y" : 687
        }
      }
    }, {
      "edgeId" : 243,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1386,
          "y" : 643
        },
        "to" : {
          "x" : 1358,
          "y" : 613
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 245,
    "reactomeId" : 5357698,
    "displayName" : "bGalNAc derivative",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1432,
      "y" : 572
    },
    "minX" : 1358,
    "maxX" : 1497,
    "minY" : 556,
    "maxY" : 613,
    "prop" : {
      "x" : 1369,
      "y" : 557,
      "width" : 127,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1370,
      "y" : 561
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1491,
          "y" : 562
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1491,
          "y" : 562
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 243,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1404,
          "y" : 590
        },
        "to" : {
          "x" : 1358,
          "y" : 613
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 251,
    "reactomeId" : 5357720,
    "displayName" : "SeO3(2-)",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1046,
      "y" : 800
    },
    "minX" : 906,
    "maxX" : 1139,
    "minY" : 764,
    "maxY" : 902,
    "prop" : {
      "x" : 1011,
      "y" : 785,
      "width" : 70,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1014,
      "y" : 789
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1076,
          "y" : 790
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1076,
          "y" : 790
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 267,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1084,
          "y" : 799
        },
        "to" : {
          "x" : 1139,
          "y" : 798
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 288,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1045,
          "y" : 818
        },
        "to" : {
          "x" : 1045,
          "y" : 902
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1049,
          "y" : 825
        },
        "b" : {
          "x" : 1045,
          "y" : 818
        },
        "c" : {
          "x" : 1041,
          "y" : 825
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1041,
          "y" : 825
        }
      }
    }, {
      "edgeId" : 250,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1008,
          "y" : 791
        },
        "to" : {
          "x" : 906,
          "y" : 764
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 252,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 947,
      "y" : 616
    },
    "minX" : 904,
    "maxX" : 970,
    "minY" : 600,
    "maxY" : 672,
    "prop" : {
      "x" : 926,
      "y" : 601,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 930,
      "y" : 605
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 964,
          "y" : 606
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 964,
          "y" : 606
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 250,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 935,
          "y" : 634
        },
        "to" : {
          "x" : 904,
          "y" : 672
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 913,
            "y" : 647
          },
          "b" : {
            "x" : 925,
            "y" : 659
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 919,
            "y" : 653
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 934,
          "y" : 642
        },
        "b" : {
          "x" : 935,
          "y" : 634
        },
        "c" : {
          "x" : 928,
          "y" : 637
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 928,
          "y" : 637
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 254,
    "reactomeId" : 29366,
    "displayName" : "NADP+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 991,
      "y" : 654
    },
    "minX" : 904,
    "maxX" : 1022,
    "minY" : 638,
    "maxY" : 672,
    "prop" : {
      "x" : 961,
      "y" : 639,
      "width" : 60,
      "height" : 30
    },
    "textPosition" : {
      "x" : 965,
      "y" : 643
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1016,
          "y" : 644
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1016,
          "y" : 644
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 250,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 958,
          "y" : 660
        },
        "to" : {
          "x" : 904,
          "y" : 672
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 925,
            "y" : 660
          },
          "b" : {
            "x" : 937,
            "y" : 672
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 931,
            "y" : 666
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 952,
          "y" : 665
        },
        "b" : {
          "x" : 958,
          "y" : 660
        },
        "c" : {
          "x" : 950,
          "y" : 658
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 950,
          "y" : 658
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 323,
    "reactomeId" : 2408526,
    "displayName" : "tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 265,
      "y" : 983
    },
    "minX" : 259,
    "maxX" : 271,
    "minY" : 942,
    "maxY" : 1014,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 266,
        "y" : 942
      },
      "to" : {
        "x" : 265,
        "y" : 983
      }
    }, {
      "from" : {
        "x" : 265,
        "y" : 983
      },
      "to" : {
        "x" : 265,
        "y" : 1014
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 259,
        "y" : 977
      },
      "b" : {
        "x" : 271,
        "y" : 989
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 265,
        "y" : 983
      }
    },
    "inputs" : [ {
      "id" : 324,
      "points" : [ {
        "x" : 222,
        "y" : 923
      } ]
    }, {
      "id" : 325,
      "points" : [ {
        "x" : 316,
        "y" : 932
      } ]
    }, {
      "id" : 328,
      "points" : [ {
        "x" : 265,
        "y" : 917
      } ]
    } ],
    "outputs" : [ {
      "id" : 326,
      "points" : [ {
        "x" : 320,
        "y" : 1029
      } ]
    }, {
      "id" : 331,
      "points" : [ {
        "x" : 229,
        "y" : 1025
      } ]
    }, {
      "id" : 330,
      "points" : [ {
        "x" : 265,
        "y" : 1051
      } ]
    }, {
      "id" : 837,
      "points" : [ {
        "x" : 228,
        "y" : 1053
      } ]
    } ],
    "catalysts" : [ {
      "id" : 327,
      "points" : [ {
        "x" : 240,
        "y" : 982
      } ]
    } ]
  }, {
    "id" : 4,
    "reactomeId" : 2408537,
    "displayName" : "Excess SeMet is cleaved into MeSeH by PXLP-K212-CTH",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 656,
      "y" : 280
    },
    "minX" : 650,
    "maxX" : 662,
    "minY" : 239,
    "maxY" : 318,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 656,
        "y" : 239
      },
      "to" : {
        "x" : 656,
        "y" : 280
      }
    }, {
      "from" : {
        "x" : 656,
        "y" : 280
      },
      "to" : {
        "x" : 656,
        "y" : 318
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 650,
        "y" : 274
      },
      "b" : {
        "x" : 662,
        "y" : 286
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 656,
        "y" : 280
      }
    },
    "inputs" : [ {
      "id" : 6,
      "points" : [ {
        "x" : 709,
        "y" : 213
      } ]
    }, {
      "id" : 5,
      "points" : [ {
        "x" : 626,
        "y" : 214
      } ]
    } ],
    "outputs" : [ {
      "id" : 7,
      "points" : [ {
        "x" : 594,
        "y" : 336
      } ]
    }, {
      "id" : 666,
      "points" : [ {
        "x" : 701,
        "y" : 339
      } ]
    }, {
      "id" : 8,
      "points" : [ {
        "x" : 717,
        "y" : 402
      } ]
    } ],
    "catalysts" : [ {
      "id" : 10,
      "points" : [ {
        "x" : 698,
        "y" : 278
      } ]
    } ]
  }, {
    "id" : 261,
    "reactomeId" : 2408500,
    "displayName" : "GSSeH condenses with GSH to form H2Se and GSSG",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 834,
      "y" : 706
    },
    "minX" : 821,
    "maxX" : 840,
    "minY" : 666,
    "maxY" : 747,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 836,
        "y" : 747
      },
      "to" : {
        "x" : 834,
        "y" : 706
      }
    }, {
      "from" : {
        "x" : 834,
        "y" : 706
      },
      "to" : {
        "x" : 821,
        "y" : 666
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 828,
        "y" : 700
      },
      "b" : {
        "x" : 840,
        "y" : 712
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 834,
        "y" : 706
      }
    },
    "inputs" : [ {
      "id" : 244,
      "points" : [ {
        "x" : 1429,
        "y" : 661
      }, {
        "x" : 1577,
        "y" : 661
      }, {
        "x" : 1579,
        "y" : 942
      }, {
        "x" : 839,
        "y" : 931
      } ]
    }, {
      "id" : 263,
      "points" : [ {
        "x" : 812,
        "y" : 757
      } ]
    } ],
    "outputs" : [ {
      "id" : 123,
      "points" : [ {
        "x" : 755,
        "y" : 607
      } ]
    }, {
      "id" : 262,
      "points" : [ {
        "x" : 780,
        "y" : 663
      } ]
    } ]
  }, {
    "id" : 197,
    "reactomeId" : 5263616,
    "displayName" : "MeSeO2H is reduced to MeSeOH by TXNRD1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1126,
      "y" : 200
    },
    "minX" : 1088,
    "maxX" : 1167,
    "minY" : 194,
    "maxY" : 206,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1167,
        "y" : 201
      },
      "to" : {
        "x" : 1126,
        "y" : 200
      }
    }, {
      "from" : {
        "x" : 1126,
        "y" : 200
      },
      "to" : {
        "x" : 1088,
        "y" : 200
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1120,
        "y" : 194
      },
      "b" : {
        "x" : 1132,
        "y" : 206
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1126,
        "y" : 200
      }
    },
    "inputs" : [ {
      "id" : 198,
      "points" : [ {
        "x" : 1232,
        "y" : 221
      } ]
    }, {
      "id" : 202,
      "points" : [ {
        "x" : 1216,
        "y" : 167
      } ]
    }, {
      "id" : 206,
      "points" : [ {
        "x" : 1170,
        "y" : 255
      } ]
    } ],
    "outputs" : [ {
      "id" : 199,
      "points" : [ {
        "x" : 1097,
        "y" : 231
      } ]
    }, {
      "id" : 192,
      "points" : [ {
        "x" : 1043,
        "y" : 214
      } ]
    }, {
      "id" : 201,
      "points" : [ {
        "x" : 1043,
        "y" : 177
      } ]
    } ],
    "catalysts" : [ {
      "id" : 205,
      "points" : [ {
        "x" : 1126,
        "y" : 165
      } ]
    } ]
  }, {
    "id" : 133,
    "reactomeId" : 2408530,
    "displayName" : "MeSeH is hydrolysed to H2Se by methylselenol demethylase",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 716,
      "y" : 504
    },
    "minX" : 710,
    "maxX" : 722,
    "minY" : 472,
    "maxY" : 545,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 716,
        "y" : 472
      },
      "to" : {
        "x" : 716,
        "y" : 504
      }
    }, {
      "from" : {
        "x" : 716,
        "y" : 504
      },
      "to" : {
        "x" : 716,
        "y" : 545
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 710,
        "y" : 498
      },
      "b" : {
        "x" : 722,
        "y" : 510
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 716,
        "y" : 504
      }
    },
    "inputs" : [ {
      "id" : 8,
      "points" : [ {
        "x" : 724,
        "y" : 438
      } ]
    }, {
      "id" : 134,
      "points" : [ {
        "x" : 657,
        "y" : 455
      } ]
    } ],
    "outputs" : [ {
      "id" : 123,
      "points" : [ {
        "x" : 733,
        "y" : 573
      } ]
    }, {
      "id" : 135,
      "points" : [ {
        "x" : 652,
        "y" : 546
      } ]
    } ],
    "catalysts" : [ {
      "id" : 136,
      "points" : [ {
        "x" : 666,
        "y" : 502
      } ]
    } ]
  }, {
    "id" : 138,
    "reactomeId" : 2408536,
    "displayName" : "H2Se is methylated to MeSeH by H2Se methyltransferase",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 751,
      "y" : 510
    },
    "minX" : 745,
    "maxX" : 757,
    "minY" : 478,
    "maxY" : 550,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 751,
        "y" : 550
      },
      "to" : {
        "x" : 751,
        "y" : 510
      }
    }, {
      "from" : {
        "x" : 751,
        "y" : 510
      },
      "to" : {
        "x" : 751,
        "y" : 478
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 745,
        "y" : 504
      },
      "b" : {
        "x" : 757,
        "y" : 516
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 751,
        "y" : 510
      }
    },
    "inputs" : [ {
      "id" : 139,
      "points" : [ {
        "x" : 786,
        "y" : 557
      } ]
    }, {
      "id" : 123,
      "points" : [ {
        "x" : 744,
        "y" : 573
      } ]
    } ],
    "outputs" : [ {
      "id" : 8,
      "points" : [ {
        "x" : 733,
        "y" : 438
      } ]
    }, {
      "id" : 140,
      "points" : [ {
        "x" : 770,
        "y" : 473
      } ]
    } ],
    "catalysts" : [ {
      "id" : 141,
      "points" : [ {
        "x" : 791,
        "y" : 510
      } ]
    } ]
  }, {
    "id" : 267,
    "reactomeId" : 2408556,
    "displayName" : "SeO3(2-) combines with GSH to form GSSeSG and GSSG",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1181,
      "y" : 801
    },
    "minX" : 1139,
    "maxX" : 1232,
    "minY" : 795,
    "maxY" : 807,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1139,
        "y" : 798
      },
      "to" : {
        "x" : 1181,
        "y" : 801
      }
    }, {
      "from" : {
        "x" : 1181,
        "y" : 801
      },
      "to" : {
        "x" : 1232,
        "y" : 802
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1175,
        "y" : 795
      },
      "b" : {
        "x" : 1187,
        "y" : 807
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1181,
        "y" : 801
      }
    },
    "inputs" : [ {
      "id" : 251,
      "points" : [ {
        "x" : 1084,
        "y" : 799
      } ]
    }, {
      "id" : 271,
      "points" : [ {
        "x" : 1091,
        "y" : 766
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 273,
      "points" : [ {
        "x" : 1127,
        "y" : 753
      } ],
      "stoichiometry" : 4
    } ],
    "outputs" : [ {
      "id" : 268,
      "points" : [ {
        "x" : 1255,
        "y" : 850
      } ],
      "stoichiometry" : 3
    }, {
      "id" : 269,
      "points" : [ {
        "x" : 1283,
        "y" : 805
      } ]
    }, {
      "id" : 274,
      "points" : [ {
        "x" : 1278,
        "y" : 774
      } ]
    } ]
  }, {
    "id" : 12,
    "reactomeId" : 2408551,
    "displayName" : "SeMet is converted to AdoSeMet by MAT",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 441,
      "y" : 309
    },
    "minX" : 435,
    "maxX" : 447,
    "minY" : 244,
    "maxY" : 402,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 440,
        "y" : 244
      },
      "to" : {
        "x" : 441,
        "y" : 309
      }
    }, {
      "from" : {
        "x" : 441,
        "y" : 309
      },
      "to" : {
        "x" : 443,
        "y" : 402
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 435,
        "y" : 303
      },
      "b" : {
        "x" : 447,
        "y" : 315
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 441,
        "y" : 309
      }
    },
    "inputs" : [ {
      "id" : 5,
      "points" : [ {
        "x" : 582,
        "y" : 203
      } ]
    }, {
      "id" : 13,
      "points" : [ {
        "x" : 362,
        "y" : 214
      } ]
    }, {
      "id" : 14,
      "points" : [ {
        "x" : 442,
        "y" : 203
      } ]
    } ],
    "outputs" : [ {
      "id" : 15,
      "points" : [ {
        "x" : 368,
        "y" : 440
      } ]
    }, {
      "id" : 16,
      "points" : [ {
        "x" : 509,
        "y" : 467
      } ]
    }, {
      "id" : 17,
      "points" : [ {
        "x" : 459,
        "y" : 477
      } ]
    } ],
    "catalysts" : [ {
      "id" : 18,
      "points" : [ {
        "x" : 479,
        "y" : 307
      } ]
    } ]
  }, {
    "id" : 333,
    "reactomeId" : 2408507,
    "displayName" : "Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 367,
      "y" : 1162
    },
    "minX" : 361,
    "maxX" : 373,
    "minY" : 1128,
    "maxY" : 1200,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 366,
        "y" : 1128
      },
      "to" : {
        "x" : 367,
        "y" : 1162
      }
    }, {
      "from" : {
        "x" : 367,
        "y" : 1162
      },
      "to" : {
        "x" : 367,
        "y" : 1200
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 361,
        "y" : 1156
      },
      "b" : {
        "x" : 373,
        "y" : 1168
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 367,
        "y" : 1162
      }
    },
    "inputs" : [ {
      "id" : 334,
      "points" : [ {
        "x" : 394,
        "y" : 1105
      } ]
    }, {
      "id" : 326,
      "points" : [ {
        "x" : 366,
        "y" : 1065
      } ]
    } ],
    "outputs" : [ {
      "id" : 335,
      "points" : [ {
        "x" : 338,
        "y" : 1212
      } ]
    }, {
      "id" : 336,
      "points" : [ {
        "x" : 399,
        "y" : 1217
      } ]
    } ],
    "catalysts" : [ {
      "id" : 337,
      "points" : [ {
        "x" : 330,
        "y" : 1161
      } ]
    } ]
  }, {
    "id" : 209,
    "reactomeId" : 5333609,
    "displayName" : "MeSebGalNac is hydrolysed to MeSeH and bGalNac",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1031,
      "y" : 416
    },
    "minX" : 975,
    "maxX" : 1072,
    "minY" : 410,
    "maxY" : 422,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1072,
        "y" : 417
      },
      "to" : {
        "x" : 1031,
        "y" : 416
      }
    }, {
      "from" : {
        "x" : 1031,
        "y" : 416
      },
      "to" : {
        "x" : 975,
        "y" : 415
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1025,
        "y" : 410
      },
      "b" : {
        "x" : 1037,
        "y" : 422
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1031,
        "y" : 416
      }
    },
    "inputs" : [ {
      "id" : 210,
      "points" : [ {
        "x" : 1087,
        "y" : 400
      } ]
    }, {
      "id" : 211,
      "points" : [ {
        "x" : 1094,
        "y" : 444
      } ]
    } ],
    "outputs" : [ {
      "id" : 212,
      "points" : [ {
        "x" : 965,
        "y" : 428
      } ]
    }, {
      "id" : 8,
      "points" : [ {
        "x" : 759,
        "y" : 419
      } ]
    } ],
    "catalysts" : [ {
      "id" : 955,
      "points" : [ {
        "x" : 1029,
        "y" : 384
      } ]
    } ]
  }, {
    "id" : 20,
    "reactomeId" : 2408544,
    "displayName" : "AdoSeMet is converted to AdeSeHCys by MetTrans(1)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 278,
      "y" : 558
    },
    "minX" : 272,
    "maxX" : 284,
    "minY" : 507,
    "maxY" : 608,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 279,
        "y" : 507
      },
      "to" : {
        "x" : 278,
        "y" : 558
      }
    }, {
      "from" : {
        "x" : 278,
        "y" : 558
      },
      "to" : {
        "x" : 278,
        "y" : 608
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 272,
        "y" : 552
      },
      "b" : {
        "x" : 284,
        "y" : 564
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 278,
        "y" : 558
      }
    },
    "inputs" : [ {
      "id" : 21,
      "points" : [ {
        "x" : 223,
        "y" : 475
      } ]
    }, {
      "id" : 15,
      "points" : [ {
        "x" : 322,
        "y" : 476
      } ]
    } ],
    "outputs" : [ {
      "id" : 23,
      "points" : [ {
        "x" : 278,
        "y" : 659
      } ]
    }, {
      "id" : 22,
      "points" : [ {
        "x" : 310,
        "y" : 621
      } ]
    }, {
      "id" : 714,
      "points" : [ {
        "x" : 241,
        "y" : 625
      } ]
    } ],
    "catalysts" : [ {
      "id" : 24,
      "points" : [ {
        "x" : 243,
        "y" : 557
      } ]
    } ]
  }, {
    "id" : 340,
    "reactomeId" : 2408555,
    "displayName" : "Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 425,
      "y" : 1338
    },
    "minX" : 419,
    "maxX" : 431,
    "minY" : 1296,
    "maxY" : 1368,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 424,
        "y" : 1296
      },
      "to" : {
        "x" : 425,
        "y" : 1338
      }
    }, {
      "from" : {
        "x" : 425,
        "y" : 1338
      },
      "to" : {
        "x" : 426,
        "y" : 1368
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 419,
        "y" : 1332
      },
      "b" : {
        "x" : 431,
        "y" : 1344
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 425,
        "y" : 1338
      }
    },
    "inputs" : [ {
      "id" : 405,
      "points" : [ {
        "x" : 388,
        "y" : 1286
      } ]
    }, {
      "id" : 336,
      "points" : [ {
        "x" : 423,
        "y" : 1253
      } ]
    }, {
      "id" : 406,
      "points" : [ {
        "x" : 446,
        "y" : 1288
      } ]
    } ],
    "outputs" : [ {
      "id" : 343,
      "points" : [ {
        "x" : 433,
        "y" : 1393
      } ]
    }, {
      "id" : 433,
      "points" : [ {
        "x" : 376,
        "y" : 1381
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 345,
      "points" : [ {
        "x" : 456,
        "y" : 1336
      } ]
    } ]
  }, {
    "id" : 276,
    "reactomeId" : 2408542,
    "displayName" : "GSSeSG is reduced to GSSeH and GSH by GSR",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1464,
      "y" : 806
    },
    "minX" : 1417,
    "maxX" : 1470,
    "minY" : 744,
    "maxY" : 812,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1417,
        "y" : 806
      },
      "to" : {
        "x" : 1464,
        "y" : 806
      }
    }, {
      "from" : {
        "x" : 1464,
        "y" : 806
      },
      "to" : {
        "x" : 1464,
        "y" : 744
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1458,
        "y" : 800
      },
      "b" : {
        "x" : 1470,
        "y" : 812
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1464,
        "y" : 806
      }
    },
    "inputs" : [ {
      "id" : 269,
      "points" : [ {
        "x" : 1349,
        "y" : 806
      } ]
    }, {
      "id" : 281,
      "points" : [ {
        "x" : 1370,
        "y" : 845
      } ]
    }, {
      "id" : 286,
      "points" : [ {
        "x" : 1382,
        "y" : 776
      } ]
    } ],
    "outputs" : [ {
      "id" : 244,
      "points" : [ {
        "x" : 1410,
        "y" : 679
      } ]
    }, {
      "id" : 279,
      "points" : [ {
        "x" : 1464,
        "y" : 712
      } ]
    }, {
      "id" : 284,
      "points" : [ {
        "x" : 1497,
        "y" : 729
      } ]
    } ],
    "catalysts" : [ {
      "id" : 277,
      "points" : [ {
        "x" : 1464,
        "y" : 844
      } ]
    } ]
  }, {
    "id" : 213,
    "reactomeId" : 2408541,
    "displayName" : "MeSeH is methylated to Me2Se by MeSeH methyltransferase",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 970,
      "y" : 491
    },
    "minX" : 911,
    "maxX" : 976,
    "minY" : 471,
    "maxY" : 577,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 911,
        "y" : 471
      },
      "to" : {
        "x" : 970,
        "y" : 491
      }
    }, {
      "from" : {
        "x" : 970,
        "y" : 491
      },
      "to" : {
        "x" : 970,
        "y" : 577
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 964,
        "y" : 485
      },
      "b" : {
        "x" : 976,
        "y" : 497
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 970,
        "y" : 491
      }
    },
    "inputs" : [ {
      "id" : 8,
      "points" : [ {
        "x" : 759,
        "y" : 427
      } ]
    }, {
      "id" : 139,
      "points" : [ {
        "x" : 834,
        "y" : 545
      } ]
    } ],
    "outputs" : [ {
      "id" : 214,
      "points" : [ {
        "x" : 1041,
        "y" : 616
      } ]
    }, {
      "id" : 218,
      "points" : [ {
        "x" : 915,
        "y" : 590
      } ]
    } ],
    "catalysts" : [ {
      "id" : 215,
      "points" : [ {
        "x" : 934,
        "y" : 512
      } ]
    } ]
  }, {
    "id" : 25,
    "reactomeId" : 2408532,
    "displayName" : "AdeSeHCys is hydrolysed to SeHCys by AHCY",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 278,
      "y" : 789
    },
    "minX" : 272,
    "maxX" : 284,
    "minY" : 752,
    "maxY" : 825,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 278,
        "y" : 752
      },
      "to" : {
        "x" : 278,
        "y" : 789
      }
    }, {
      "from" : {
        "x" : 278,
        "y" : 789
      },
      "to" : {
        "x" : 278,
        "y" : 825
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 272,
        "y" : 783
      },
      "b" : {
        "x" : 284,
        "y" : 795
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 278,
        "y" : 789
      }
    },
    "inputs" : [ {
      "id" : 26,
      "points" : [ {
        "x" : 260,
        "y" : 743
      } ]
    }, {
      "id" : 23,
      "points" : [ {
        "x" : 278,
        "y" : 695
      } ]
    } ],
    "outputs" : [ {
      "id" : 27,
      "points" : [ {
        "x" : 316,
        "y" : 845
      } ]
    }, {
      "id" : 28,
      "points" : [ {
        "x" : 314,
        "y" : 809
      } ]
    } ],
    "catalysts" : [ {
      "id" : 29,
      "points" : [ {
        "x" : 247,
        "y" : 787
      } ]
    } ]
  }, {
    "id" : 220,
    "reactomeId" : 2408554,
    "displayName" : "Me2Se is methylated to Me3Se+ by INMT",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1184,
      "y" : 663
    },
    "minX" : 1143,
    "maxX" : 1239,
    "minY" : 657,
    "maxY" : 669,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1143,
        "y" : 662
      },
      "to" : {
        "x" : 1184,
        "y" : 663
      }
    }, {
      "from" : {
        "x" : 1184,
        "y" : 663
      },
      "to" : {
        "x" : 1239,
        "y" : 664
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1178,
        "y" : 657
      },
      "b" : {
        "x" : 1190,
        "y" : 669
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1184,
        "y" : 663
      }
    },
    "inputs" : [ {
      "id" : 214,
      "points" : [ {
        "x" : 1098,
        "y" : 644
      } ]
    }, {
      "id" : 227,
      "points" : [ {
        "x" : 1110,
        "y" : 677
      } ]
    } ],
    "outputs" : [ {
      "id" : 221,
      "points" : [ {
        "x" : 1293,
        "y" : 704
      } ]
    }, {
      "id" : 226,
      "points" : [ {
        "x" : 1288,
        "y" : 665
      } ]
    } ],
    "catalysts" : [ {
      "id" : 222,
      "points" : [ {
        "x" : 1186,
        "y" : 700
      } ]
    } ]
  }, {
    "id" : 348,
    "reactomeId" : 2408509,
    "displayName" : "Sec-tRNA(Sec) binds to EEFSEC:GTP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 592,
      "y" : 1411
    },
    "minX" : 549,
    "maxX" : 650,
    "minY" : 1405,
    "maxY" : 1417,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 549,
        "y" : 1411
      },
      "to" : {
        "x" : 592,
        "y" : 1411
      }
    }, {
      "from" : {
        "x" : 592,
        "y" : 1411
      },
      "to" : {
        "x" : 650,
        "y" : 1411
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 643,
        "y" : 1415
      },
      "b" : {
        "x" : 650,
        "y" : 1411
      },
      "c" : {
        "x" : 643,
        "y" : 1407
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 643,
        "y" : 1407
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 586,
        "y" : 1405
      },
      "b" : {
        "x" : 598,
        "y" : 1417
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 592,
        "y" : 1411
      }
    },
    "inputs" : [ {
      "id" : 343,
      "points" : [ {
        "x" : 491,
        "y" : 1411
      } ]
    }, {
      "id" : 349,
      "points" : [ {
        "x" : 524,
        "y" : 1447
      } ]
    } ],
    "outputs" : [ {
      "id" : 350
    } ],
    "catalysts" : [ {
      "id" : 349,
      "points" : [ {
        "x" : 560,
        "y" : 1458
      }, {
        "x" : 593,
        "y" : 1457
      } ]
    } ]
  }, {
    "id" : 351,
    "reactomeId" : 2408529,
    "displayName" : "Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 869,
      "y" : 1412
    },
    "minX" : 813,
    "maxX" : 875,
    "minY" : 1289,
    "maxY" : 1418,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 813,
        "y" : 1413
      },
      "to" : {
        "x" : 869,
        "y" : 1412
      }
    }, {
      "from" : {
        "x" : 869,
        "y" : 1412
      },
      "to" : {
        "x" : 867,
        "y" : 1289
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 871,
        "y" : 1296
      },
      "b" : {
        "x" : 867,
        "y" : 1289
      },
      "c" : {
        "x" : 863,
        "y" : 1296
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 863,
        "y" : 1296
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 863,
        "y" : 1406
      },
      "b" : {
        "x" : 875,
        "y" : 1418
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 869,
        "y" : 1412
      }
    },
    "inputs" : [ {
      "id" : 350,
      "points" : [ {
        "x" : 751,
        "y" : 1411
      } ]
    }, {
      "id" : 352,
      "points" : [ {
        "x" : 769,
        "y" : 1366
      } ]
    }, {
      "id" : 353,
      "points" : [ {
        "x" : 775,
        "y" : 1450
      } ]
    } ],
    "outputs" : [ {
      "id" : 354
    } ],
    "catalysts" : [ {
      "id" : 353,
      "points" : [ {
        "x" : 799,
        "y" : 1463
      }, {
        "x" : 869,
        "y" : 1462
      } ]
    } ]
  }, {
    "id" : 288,
    "reactomeId" : 2408548,
    "displayName" : "PAPSe is reduced to SeO3(2-) by PAPSe reductase",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1046,
      "y" : 959
    },
    "minX" : 1040,
    "maxX" : 1052,
    "minY" : 902,
    "maxY" : 993,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1047,
        "y" : 993
      },
      "to" : {
        "x" : 1046,
        "y" : 959
      }
    }, {
      "from" : {
        "x" : 1046,
        "y" : 959
      },
      "to" : {
        "x" : 1045,
        "y" : 902
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1040,
        "y" : 953
      },
      "b" : {
        "x" : 1052,
        "y" : 965
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1046,
        "y" : 959
      }
    },
    "inputs" : [ {
      "id" : 289,
      "points" : [ {
        "x" : 1096,
        "y" : 1024
      } ]
    }, {
      "id" : 297,
      "points" : [ {
        "x" : 1002,
        "y" : 1010
      } ]
    }, {
      "id" : 293,
      "points" : [ {
        "x" : 1040,
        "y" : 1029
      } ]
    } ],
    "outputs" : [ {
      "id" : 251,
      "points" : [ {
        "x" : 1045,
        "y" : 818
      } ]
    }, {
      "id" : 361,
      "points" : [ {
        "x" : 1081,
        "y" : 874
      } ]
    }, {
      "id" : 290,
      "points" : [ {
        "x" : 1119,
        "y" : 902
      } ]
    }, {
      "id" : 295,
      "points" : [ {
        "x" : 1020,
        "y" : 896
      } ]
    } ],
    "catalysts" : [ {
      "id" : 291,
      "points" : [ {
        "x" : 1099,
        "y" : 960
      } ]
    } ]
  }, {
    "id" : 418,
    "reactomeId" : 8959510,
    "displayName" : "SEPHS2 phosphorylates H2Se to form SELP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 211,
      "y" : 1282
    },
    "minX" : 153,
    "maxX" : 249,
    "minY" : 1276,
    "maxY" : 1288,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 153,
        "y" : 1282
      },
      "to" : {
        "x" : 211,
        "y" : 1282
      }
    }, {
      "from" : {
        "x" : 211,
        "y" : 1282
      },
      "to" : {
        "x" : 249,
        "y" : 1282
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 205,
        "y" : 1276
      },
      "b" : {
        "x" : 217,
        "y" : 1288
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 211,
        "y" : 1282
      }
    },
    "inputs" : [ {
      "id" : 419,
      "points" : [ {
        "x" : 125,
        "y" : 1306
      } ]
    }, {
      "id" : 420,
      "points" : [ {
        "x" : 122,
        "y" : 1260
      } ]
    }, {
      "id" : 123,
      "points" : [ {
        "x" : 707,
        "y" : 590
      }, {
        "x" : 155,
        "y" : 594
      } ]
    } ],
    "outputs" : [ {
      "id" : 405,
      "points" : [ {
        "x" : 339,
        "y" : 1281
      } ]
    }, {
      "id" : 426,
      "points" : [ {
        "x" : 281,
        "y" : 1307
      } ]
    }, {
      "id" : 428,
      "points" : [ {
        "x" : 269,
        "y" : 1345
      } ]
    }, {
      "id" : 430,
      "points" : [ {
        "x" : 238,
        "y" : 1321
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 421,
      "points" : [ {
        "x" : 209,
        "y" : 1247
      } ]
    } ]
  }, {
    "id" : 356,
    "reactomeId" : 5333615,
    "displayName" : "80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 863,
      "y" : 1117
    },
    "minX" : 715,
    "maxX" : 952,
    "minY" : 1111,
    "maxY" : 1123,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 952,
        "y" : 1117
      },
      "to" : {
        "x" : 863,
        "y" : 1117
      }
    }, {
      "from" : {
        "x" : 863,
        "y" : 1117
      },
      "to" : {
        "x" : 715,
        "y" : 1118
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 857,
        "y" : 1111
      },
      "b" : {
        "x" : 869,
        "y" : 1123
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 863,
        "y" : 1117
      }
    },
    "inputs" : [ {
      "id" : 357,
      "points" : [ {
        "x" : 984,
        "y" : 1117
      } ]
    }, {
      "id" : 354,
      "points" : [ {
        "x" : 936,
        "y" : 1250
      }, {
        "x" : 954,
        "y" : 1250
      } ]
    } ],
    "outputs" : [ {
      "id" : 358,
      "points" : [ {
        "x" : 642,
        "y" : 1034
      } ]
    }, {
      "id" : 359,
      "points" : [ {
        "x" : 745,
        "y" : 1040
      } ]
    }, {
      "id" : 325,
      "points" : [ {
        "x" : 383,
        "y" : 944
      } ]
    }, {
      "id" : 360,
      "points" : [ {
        "x" : 633,
        "y" : 1155
      } ]
    } ],
    "catalysts" : [ {
      "id" : 354,
      "points" : [ {
        "x" : 866,
        "y" : 1219
      } ]
    } ]
  }, {
    "id" : 229,
    "reactomeId" : 5333612,
    "displayName" : "MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1199,
      "y" : 460
    },
    "minX" : 1157,
    "maxX" : 1272,
    "minY" : 454,
    "maxY" : 466,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1157,
        "y" : 460
      },
      "to" : {
        "x" : 1199,
        "y" : 460
      }
    }, {
      "from" : {
        "x" : 1199,
        "y" : 460
      },
      "to" : {
        "x" : 1272,
        "y" : 460
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1193,
        "y" : 454
      },
      "b" : {
        "x" : 1205,
        "y" : 466
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1199,
        "y" : 460
      }
    },
    "inputs" : [ {
      "id" : 211
    } ],
    "outputs" : [ {
      "id" : 230,
      "points" : [ {
        "x" : 1305,
        "y" : 463
      } ]
    }, {
      "id" : 198,
      "points" : [ {
        "x" : 1271,
        "y" : 250
      } ]
    } ],
    "catalysts" : [ {
      "id" : 1048,
      "points" : [ {
        "x" : 1198,
        "y" : 427
      } ]
    } ]
  }, {
    "id" : 103,
    "reactomeId" : 2408559,
    "displayName" : "SeHCys and Ser are dehydrated into SeCysta by CBS",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 450,
      "y" : 793
    },
    "minX" : 403,
    "maxX" : 496,
    "minY" : 787,
    "maxY" : 799,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 403,
        "y" : 794
      },
      "to" : {
        "x" : 450,
        "y" : 793
      }
    }, {
      "from" : {
        "x" : 450,
        "y" : 793
      },
      "to" : {
        "x" : 496,
        "y" : 793
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 444,
        "y" : 787
      },
      "b" : {
        "x" : 456,
        "y" : 799
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 450,
        "y" : 793
      }
    },
    "inputs" : [ {
      "id" : 104,
      "points" : [ {
        "x" : 396,
        "y" : 755
      } ]
    }, {
      "id" : 28,
      "points" : [ {
        "x" : 379,
        "y" : 795
      } ]
    } ],
    "outputs" : [ {
      "id" : 105,
      "points" : [ {
        "x" : 535,
        "y" : 838
      } ]
    }, {
      "id" : 106,
      "points" : [ {
        "x" : 517,
        "y" : 783
      } ]
    } ],
    "catalysts" : [ {
      "id" : 107,
      "points" : [ {
        "x" : 452,
        "y" : 824
      } ]
    } ]
  }, {
    "id" : 234,
    "reactomeId" : 5333608,
    "displayName" : "GSSebGalNac is reduced and methylated to MeSebGalNac",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1105,
      "y" : 537
    },
    "minX" : 1099,
    "maxX" : 1111,
    "minY" : 518,
    "maxY" : 562,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1105,
        "y" : 562
      },
      "to" : {
        "x" : 1105,
        "y" : 537
      }
    }, {
      "from" : {
        "x" : 1105,
        "y" : 537
      },
      "to" : {
        "x" : 1105,
        "y" : 518
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1099,
        "y" : 531
      },
      "b" : {
        "x" : 1111,
        "y" : 543
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1105,
        "y" : 537
      }
    },
    "inputs" : [ {
      "id" : 235,
      "points" : [ {
        "x" : 1176,
        "y" : 588
      } ]
    }, {
      "id" : 238,
      "points" : [ {
        "x" : 1081,
        "y" : 568
      } ]
    } ],
    "outputs" : [ {
      "id" : 211,
      "points" : [ {
        "x" : 1105,
        "y" : 480
      } ]
    }, {
      "id" : 236,
      "points" : [ {
        "x" : 1142,
        "y" : 501
      } ]
    }, {
      "id" : 240,
      "points" : [ {
        "x" : 1068,
        "y" : 501
      } ]
    } ],
    "catalysts" : [ {
      "id" : 931,
      "points" : [ {
        "x" : 1164,
        "y" : 537
      } ]
    } ]
  }, {
    "id" : 300,
    "reactomeId" : 2408540,
    "displayName" : "APSe is phosphorylated to PAPSe by PAPSS1,2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1233,
      "y" : 1074
    },
    "minX" : 1188,
    "maxX" : 1278,
    "minY" : 1068,
    "maxY" : 1080,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1278,
        "y" : 1073
      },
      "to" : {
        "x" : 1233,
        "y" : 1074
      }
    }, {
      "from" : {
        "x" : 1233,
        "y" : 1074
      },
      "to" : {
        "x" : 1188,
        "y" : 1075
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1227,
        "y" : 1068
      },
      "b" : {
        "x" : 1239,
        "y" : 1080
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1233,
        "y" : 1074
      }
    },
    "inputs" : [ {
      "id" : 301,
      "points" : [ {
        "x" : 1303,
        "y" : 1055
      } ]
    }, {
      "id" : 302,
      "points" : [ {
        "x" : 1303,
        "y" : 1099
      } ]
    } ],
    "outputs" : [ {
      "id" : 303,
      "points" : [ {
        "x" : 1160,
        "y" : 1102
      } ]
    }, {
      "id" : 289,
      "points" : [ {
        "x" : 1147,
        "y" : 1054
      } ]
    } ],
    "catalysts" : [ {
      "id" : 304,
      "points" : [ {
        "x" : 1235,
        "y" : 1122
      } ]
    } ]
  }, {
    "id" : 109,
    "reactomeId" : 2408543,
    "displayName" : "SeCysta is hydrolysed to Sec by PXLP-K212-CTH",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 649,
      "y" : 813
    },
    "minX" : 613,
    "maxX" : 675,
    "minY" : 807,
    "maxY" : 819,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 613,
        "y" : 814
      },
      "to" : {
        "x" : 649,
        "y" : 813
      }
    }, {
      "from" : {
        "x" : 649,
        "y" : 813
      },
      "to" : {
        "x" : 675,
        "y" : 813
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 643,
        "y" : 807
      },
      "b" : {
        "x" : 655,
        "y" : 819
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 649,
        "y" : 813
      }
    },
    "inputs" : [ {
      "id" : 106,
      "points" : [ {
        "x" : 564,
        "y" : 783
      } ]
    }, {
      "id" : 105,
      "points" : [ {
        "x" : 573,
        "y" : 842
      } ]
    } ],
    "outputs" : [ {
      "id" : 111,
      "points" : [ {
        "x" : 705,
        "y" : 786
      } ]
    }, {
      "id" : 115,
      "points" : [ {
        "x" : 698,
        "y" : 836
      } ]
    }, {
      "id" : 784,
      "points" : [ {
        "x" : 715,
        "y" : 811
      } ]
    } ],
    "catalysts" : [ {
      "id" : 117,
      "points" : [ {
        "x" : 648,
        "y" : 876
      } ]
    } ]
  }, {
    "id" : 306,
    "reactomeId" : 2408525,
    "displayName" : "H2SeO4 is converted to APSe by PAPSS1,2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1443,
      "y" : 1072
    },
    "minX" : 1399,
    "maxX" : 1484,
    "minY" : 1066,
    "maxY" : 1078,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1484,
        "y" : 1072
      },
      "to" : {
        "x" : 1443,
        "y" : 1072
      }
    }, {
      "from" : {
        "x" : 1443,
        "y" : 1072
      },
      "to" : {
        "x" : 1399,
        "y" : 1072
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1437,
        "y" : 1066
      },
      "b" : {
        "x" : 1449,
        "y" : 1078
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1443,
        "y" : 1072
      }
    },
    "inputs" : [ {
      "id" : 307,
      "points" : [ {
        "x" : 1513,
        "y" : 1053
      } ]
    }, {
      "id" : 308,
      "points" : [ {
        "x" : 1507,
        "y" : 1098
      } ]
    } ],
    "outputs" : [ {
      "id" : 301,
      "points" : [ {
        "x" : 1354,
        "y" : 1051
      } ]
    }, {
      "id" : 309,
      "points" : [ {
        "x" : 1375,
        "y" : 1098
      } ]
    } ],
    "catalysts" : [ {
      "id" : 310,
      "points" : [ {
        "x" : 1443,
        "y" : 1119
      } ]
    } ]
  }, {
    "id" : 243,
    "reactomeId" : 5333607,
    "displayName" : "GSSeH combines with bGalNAc derivative to form GSSebGalNac",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1317,
      "y" : 612
    },
    "minX" : 1263,
    "maxX" : 1358,
    "minY" : 606,
    "maxY" : 618,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1358,
        "y" : 613
      },
      "to" : {
        "x" : 1317,
        "y" : 612
      }
    }, {
      "from" : {
        "x" : 1317,
        "y" : 612
      },
      "to" : {
        "x" : 1263,
        "y" : 608
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1270,
        "y" : 605
      },
      "b" : {
        "x" : 1263,
        "y" : 608
      },
      "c" : {
        "x" : 1270,
        "y" : 613
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1270,
        "y" : 613
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1311,
        "y" : 606
      },
      "b" : {
        "x" : 1323,
        "y" : 618
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1317,
        "y" : 612
      }
    },
    "inputs" : [ {
      "id" : 244,
      "points" : [ {
        "x" : 1386,
        "y" : 643
      } ]
    }, {
      "id" : 245,
      "points" : [ {
        "x" : 1404,
        "y" : 590
      } ]
    } ],
    "outputs" : [ {
      "id" : 235
    } ],
    "catalysts" : [ {
      "id" : 907,
      "points" : [ {
        "x" : 1314,
        "y" : 576
      } ]
    } ]
  }, {
    "id" : 312,
    "reactomeId" : 2408546,
    "displayName" : "tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 659,
      "y" : 124
    },
    "minX" : 611,
    "maxX" : 715,
    "minY" : 118,
    "maxY" : 130,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 611,
        "y" : 125
      },
      "to" : {
        "x" : 659,
        "y" : 124
      }
    }, {
      "from" : {
        "x" : 659,
        "y" : 124
      },
      "to" : {
        "x" : 715,
        "y" : 123
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 653,
        "y" : 118
      },
      "b" : {
        "x" : 665,
        "y" : 130
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 659,
        "y" : 124
      }
    },
    "inputs" : [ {
      "id" : 313,
      "points" : [ {
        "x" : 566,
        "y" : 113
      } ]
    }, {
      "id" : 5,
      "points" : [ {
        "x" : 610,
        "y" : 178
      } ]
    }, {
      "id" : 314,
      "points" : [ {
        "x" : 581,
        "y" : 85
      } ]
    } ],
    "outputs" : [ {
      "id" : 315,
      "points" : [ {
        "x" : 760,
        "y" : 146
      } ]
    }, {
      "id" : 316,
      "points" : [ {
        "x" : 790,
        "y" : 122
      } ]
    }, {
      "id" : 319,
      "points" : [ {
        "x" : 762,
        "y" : 93
      } ]
    } ],
    "catalysts" : [ {
      "id" : 317,
      "points" : [ {
        "x" : 660,
        "y" : 97
      } ]
    } ]
  }, {
    "id" : 120,
    "reactomeId" : 2408524,
    "displayName" : "Sec is reduced to H2Se by PXLP-K259-SCLY dimer",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 713,
      "y" : 682
    },
    "minX" : 707,
    "maxX" : 723,
    "minY" : 644,
    "maxY" : 722,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 714,
        "y" : 722
      },
      "to" : {
        "x" : 713,
        "y" : 682
      }
    }, {
      "from" : {
        "x" : 713,
        "y" : 682
      },
      "to" : {
        "x" : 723,
        "y" : 644
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 707,
        "y" : 676
      },
      "b" : {
        "x" : 719,
        "y" : 688
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 713,
        "y" : 682
      }
    },
    "inputs" : [ {
      "id" : 785,
      "points" : [ {
        "x" : 699,
        "y" : 726
      } ]
    }, {
      "id" : 111,
      "points" : [ {
        "x" : 718,
        "y" : 750
      } ]
    } ],
    "outputs" : [ {
      "id" : 122,
      "points" : [ {
        "x" : 685,
        "y" : 654
      } ]
    }, {
      "id" : 809,
      "points" : [ {
        "x" : 645,
        "y" : 634
      } ]
    }, {
      "id" : 123,
      "points" : [ {
        "x" : 736,
        "y" : 607
      } ]
    }, {
      "id" : 811,
      "points" : [ {
        "x" : 691,
        "y" : 623
      } ]
    } ],
    "catalysts" : [ {
      "id" : 125,
      "points" : [ {
        "x" : 605,
        "y" : 686
      } ]
    } ]
  }, {
    "id" : 250,
    "reactomeId" : 2408558,
    "displayName" : "SeO3(2-) is reduced to H2Se by TXNRD1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 906,
      "y" : 722
    },
    "minX" : 900,
    "maxX" : 912,
    "minY" : 672,
    "maxY" : 764,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 906,
        "y" : 764
      },
      "to" : {
        "x" : 906,
        "y" : 722
      }
    }, {
      "from" : {
        "x" : 906,
        "y" : 722
      },
      "to" : {
        "x" : 904,
        "y" : 672
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 900,
        "y" : 716
      },
      "b" : {
        "x" : 912,
        "y" : 728
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 906,
        "y" : 722
      }
    },
    "inputs" : [ {
      "id" : 251,
      "points" : [ {
        "x" : 1008,
        "y" : 791
      } ]
    }, {
      "id" : 363,
      "points" : [ {
        "x" : 904,
        "y" : 822
      } ],
      "stoichiometry" : 3
    }, {
      "id" : 365,
      "points" : [ {
        "x" : 954,
        "y" : 821
      } ],
      "stoichiometry" : 3
    } ],
    "outputs" : [ {
      "id" : 123,
      "points" : [ {
        "x" : 768,
        "y" : 607
      } ]
    }, {
      "id" : 252,
      "points" : [ {
        "x" : 935,
        "y" : 634
      } ],
      "stoichiometry" : 3
    }, {
      "id" : 254,
      "points" : [ {
        "x" : 958,
        "y" : 660
      } ],
      "stoichiometry" : 3
    } ],
    "catalysts" : [ {
      "id" : 260,
      "points" : [ {
        "x" : 937,
        "y" : 721
      } ]
    } ]
  }, {
    "id" : 190,
    "reactomeId" : 5263614,
    "displayName" : "MeSeOH is reduced to MeSeH by TXNRD1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 950,
      "y" : 353
    },
    "minX" : 871,
    "maxX" : 956,
    "minY" : 262,
    "maxY" : 391,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 950,
        "y" : 262
      },
      "to" : {
        "x" : 950,
        "y" : 353
      }
    }, {
      "from" : {
        "x" : 950,
        "y" : 353
      },
      "to" : {
        "x" : 871,
        "y" : 391
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 944,
        "y" : 347
      },
      "b" : {
        "x" : 956,
        "y" : 359
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 950,
        "y" : 353
      }
    },
    "inputs" : [ {
      "id" : 191,
      "points" : [ {
        "x" : 922,
        "y" : 248
      } ]
    }, {
      "id" : 192,
      "points" : [ {
        "x" : 984,
        "y" : 242
      } ]
    }, {
      "id" : 193,
      "points" : [ {
        "x" : 947,
        "y" : 212
      } ]
    } ],
    "outputs" : [ {
      "id" : 8,
      "points" : [ {
        "x" : 759,
        "y" : 414
      } ]
    }, {
      "id" : 194,
      "points" : [ {
        "x" : 933,
        "y" : 388
      } ]
    }, {
      "id" : 195,
      "points" : [ {
        "x" : 877,
        "y" : 364
      } ]
    } ],
    "catalysts" : [ {
      "id" : 196,
      "points" : [ {
        "x" : 906,
        "y" : 321
      } ]
    } ]
  }, {
    "id" : 127,
    "reactomeId" : 2408539,
    "displayName" : "MeSec is hydrolysed to MeSeH by PXLP-K212-CTH",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 805,
      "y" : 278
    },
    "minX" : 799,
    "maxX" : 811,
    "minY" : 235,
    "maxY" : 314,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 804,
        "y" : 235
      },
      "to" : {
        "x" : 805,
        "y" : 278
      }
    }, {
      "from" : {
        "x" : 805,
        "y" : 278
      },
      "to" : {
        "x" : 807,
        "y" : 314
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 799,
        "y" : 272
      },
      "b" : {
        "x" : 811,
        "y" : 284
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 805,
        "y" : 278
      }
    },
    "inputs" : [ {
      "id" : 129,
      "points" : [ {
        "x" : 833,
        "y" : 213
      } ]
    }, {
      "id" : 6,
      "points" : [ {
        "x" : 758,
        "y" : 213
      } ]
    } ],
    "outputs" : [ {
      "id" : 666,
      "points" : [ {
        "x" : 760,
        "y" : 338
      } ]
    }, {
      "id" : 835,
      "points" : [ {
        "x" : 809,
        "y" : 353
      } ]
    }, {
      "id" : 8,
      "points" : [ {
        "x" : 739,
        "y" : 402
      } ]
    } ],
    "catalysts" : [ {
      "id" : 10,
      "points" : [ {
        "x" : 766,
        "y" : 278
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 1,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 888,
      "y" : 749
    },
    "minX" : 0,
    "maxX" : 1776,
    "minY" : 0,
    "maxY" : 1499,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 1776,
      "height" : 1499
    },
    "textPosition" : {
      "x" : 19,
      "y" : 1452
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 1758,
      "height" : 1480
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 4, 5, 6, 7, 8, 10, 12, 13, 14, 15, 16, 18, 17, 20, 21, 22, 23, 24, 26, 27, 28, 29, 25, 103, 104, 105, 106, 107, 109, 111, 115, 117, 120, 122, 123, 125, 127, 129, 133, 134, 135, 136, 138, 139, 140, 141, 190, 191, 192, 193, 194, 195, 196, 197, 199, 201, 205, 198, 202, 206, 209, 210, 211, 212, 213, 214, 215, 218, 220, 221, 222, 226, 227, 229, 230, 234, 235, 236, 238, 240, 243, 244, 245, 250, 251, 252, 254, 260, 261, 262, 263, 267, 268, 269, 271, 273, 274, 276, 277, 279, 281, 284, 286, 288, 289, 290, 291, 293, 295, 297, 300, 301, 302, 303, 304, 306, 307, 308, 309, 310, 312, 313, 314, 319, 315, 316, 317, 323, 324, 325, 326, 327, 328, 330, 331, 333, 334, 335, 336, 337, 340, 343, 345, 348, 349, 350, 351, 352, 353, 354, 356, 357, 358, 359, 360, 361, 363, 365, 406, 405, 418, 421, 420, 419, 426, 428, 430, 433, 666, 714, 784, 785, 809, 811, 835, 837, 907, 931, 955, 1048 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ {
    "id" : 1049,
    "reactomeId" : 2408499,
    "displayName" : "Formation of selenosugars for excretion",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1098,
      "y" : 446
    },
    "minX" : 690,
    "maxX" : 1506,
    "minY" : 207,
    "maxY" : 686,
    "prop" : {
      "x" : 1318,
      "y" : 207,
      "width" : 188,
      "height" : 188
    },
    "points" : [ {
      "x" : 690,
      "y" : 207
    }, {
      "x" : 1506,
      "y" : 207
    }, {
      "x" : 1506,
      "y" : 686
    }, {
      "x" : 690,
      "y" : 686
    } ],
    "colour" : "#4684ee"
  }, {
    "id" : 1050,
    "reactomeId" : 2408508,
    "displayName" : "Metabolism of ingested SeMet, Sec, MeSec into H2Se",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 518,
      "y" : 544
    },
    "minX" : 148,
    "maxX" : 888,
    "minY" : 160,
    "maxY" : 929,
    "prop" : {
      "x" : 148,
      "y" : 445,
      "width" : 542,
      "height" : 121
    },
    "points" : [ {
      "x" : 148,
      "y" : 160
    }, {
      "x" : 888,
      "y" : 160
    }, {
      "x" : 888,
      "y" : 929
    }, {
      "x" : 148,
      "y" : 929
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 1051,
    "reactomeId" : 2408550,
    "displayName" : "Metabolism of ingested H2SeO4 and H2SeO3 into H2Se",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1138,
      "y" : 863
    },
    "minX" : 700,
    "maxX" : 1576,
    "minY" : 566,
    "maxY" : 1160,
    "prop" : {
      "x" : 1040,
      "y" : 747,
      "width" : 536,
      "height" : 413
    },
    "points" : [ {
      "x" : 700,
      "y" : 566
    }, {
      "x" : 1576,
      "y" : 566
    }, {
      "x" : 1576,
      "y" : 1160
    }, {
      "x" : 700,
      "y" : 1160
    } ],
    "colour" : "#008000"
  }, {
    "id" : 1052,
    "reactomeId" : 2408552,
    "displayName" : "Methylation of MeSeH for excretion",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1026,
      "y" : 571
    },
    "minX" : 690,
    "maxX" : 1362,
    "minY" : 395,
    "maxY" : 747,
    "prop" : {
      "x" : 690,
      "y" : 395,
      "width" : 672,
      "height" : 352
    },
    "points" : [ {
      "x" : 690,
      "y" : 395
    }, {
      "x" : 1362,
      "y" : 395
    }, {
      "x" : 1362,
      "y" : 747
    }, {
      "x" : 690,
      "y" : 747
    } ],
    "colour" : "#666666"
  }, {
    "id" : 1053,
    "reactomeId" : 2408557,
    "displayName" : "Selenocysteine synthesis",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 553,
      "y" : 1025
    },
    "minX" : 66,
    "maxX" : 1040,
    "minY" : 566,
    "maxY" : 1485,
    "prop" : {
      "x" : 66,
      "y" : 1160,
      "width" : 974,
      "height" : 325
    },
    "points" : [ {
      "x" : 66,
      "y" : 566
    }, {
      "x" : 1040,
      "y" : 566
    }, {
      "x" : 1040,
      "y" : 1485
    }, {
      "x" : 66,
      "y" : 1485
    } ],
    "colour" : "#4942cc"
  }, {
    "id" : 1054,
    "reactomeId" : 5263617,
    "displayName" : "Metabolism of ingested MeSeO2H into MeSeH",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1004,
      "y" : 280
    },
    "minX" : 690,
    "maxX" : 1318,
    "minY" : 115,
    "maxY" : 445,
    "prop" : {
      "x" : 690,
      "y" : 115,
      "width" : 628,
      "height" : 45
    },
    "points" : [ {
      "x" : 690,
      "y" : 115
    }, {
      "x" : 1318,
      "y" : 115
    }, {
      "x" : 1318,
      "y" : 445
    }, {
      "x" : 690,
      "y" : 445
    } ],
    "colour" : "#cb4ac5"
  } ],
  "minX" : 0,
  "maxX" : 1776,
  "minY" : 0,
  "maxY" : 1499,
  "disease" : false
}