{
  "dbId" : 157579,
  "stableId" : "R-HSA-157579",
  "displayName" : "Telomere Maintenance",
  "forNormalDraw" : true,
  "nodes" : [ {
    "id" : 2,
    "reactomeId" : 29892,
    "displayName" : "dGTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 840,
      "y" : 288
    },
    "minX" : 705,
    "maxX" : 956,
    "minY" : 274,
    "maxY" : 555,
    "prop" : {
      "x" : 817,
      "y" : 275,
      "width" : 47,
      "height" : 27
    },
    "textPosition" : {
      "x" : 820,
      "y" : 278
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 859,
          "y" : 280
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 859,
          "y" : 280
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 21,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 821,
          "y" : 305
        },
        "to" : {
          "x" : 773,
          "y" : 336
        }
      }, {
        "from" : {
          "x" : 773,
          "y" : 336
        },
        "to" : {
          "x" : 705,
          "y" : 350
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 23,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 840,
          "y" : 305
        },
        "to" : {
          "x" : 843,
          "y" : 521
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 40,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 858,
          "y" : 305
        },
        "to" : {
          "x" : 937,
          "y" : 357
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 57,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 845,
          "y" : 305
        },
        "to" : {
          "x" : 956,
          "y" : 555
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3,
    "reactomeId" : 163102,
    "displayName" : "DKC1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 89,
      "y" : 428
    },
    "minX" : 67,
    "maxX" : 249,
    "minY" : 411,
    "maxY" : 735,
    "prop" : {
      "x" : 67,
      "y" : 417,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 69,
      "y" : 417
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 112,
          "y" : 417
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 112,
          "y" : 417
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 115,
          "y" : 430
        },
        "to" : {
          "x" : 249,
          "y" : 449
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 176,
            "y" : 433
          },
          "b" : {
            "x" : 188,
            "y" : 445
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 182,
            "y" : 439
          }
        }
      }
    }, {
      "edgeId" : 3615,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 91,
          "y" : 442
        },
        "to" : {
          "x" : 154,
          "y" : 735
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 4,
    "reactomeId" : 418386,
    "displayName" : "WRAP53",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 232,
      "y" : 604
    },
    "minX" : 198,
    "maxX" : 272,
    "minY" : 449,
    "maxY" : 615,
    "prop" : {
      "x" : 198,
      "y" : 593,
      "width" : 68,
      "height" : 22
    },
    "textPosition" : {
      "x" : 202,
      "y" : 593
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 266,
          "y" : 593
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 266,
          "y" : 593
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 233,
          "y" : 590
        },
        "to" : {
          "x" : 249,
          "y" : 449
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 6,
    "reactomeId" : 163076,
    "displayName" : "TERT",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 93,
      "y" : 385
    },
    "minX" : 71,
    "maxX" : 249,
    "minY" : 368,
    "maxY" : 449,
    "prop" : {
      "x" : 71,
      "y" : 374,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 74,
      "y" : 374
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 116,
          "y" : 374
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 116,
          "y" : 374
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 119,
          "y" : 394
        },
        "to" : {
          "x" : 249,
          "y" : 449
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 7,
    "reactomeId" : 163077,
    "displayName" : "Telomerase RNA Component (TERC)",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "RNA",
    "position" : {
      "x" : 214,
      "y" : 370
    },
    "minX" : 149,
    "maxX" : 279,
    "minY" : 345,
    "maxY" : 449,
    "prop" : {
      "x" : 149,
      "y" : 345,
      "width" : 130,
      "height" : 51
    },
    "textPosition" : {
      "x" : 151,
      "y" : 353
    },
    "connectors" : [ {
      "edgeId" : 26,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 225,
          "y" : 391
        },
        "to" : {
          "x" : 249,
          "y" : 449
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 8,
    "reactomeId" : 30187,
    "displayName" : "dTTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 814,
      "y" : 338
    },
    "minX" : 705,
    "maxX" : 956,
    "minY" : 324,
    "maxY" : 555,
    "prop" : {
      "x" : 790,
      "y" : 325,
      "width" : 48,
      "height" : 26
    },
    "textPosition" : {
      "x" : 795,
      "y" : 327
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 833,
          "y" : 330
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 833,
          "y" : 330
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 21,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 787,
          "y" : 340
        },
        "to" : {
          "x" : 705,
          "y" : 350
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 23,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 816,
          "y" : 354
        },
        "to" : {
          "x" : 843,
          "y" : 521
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 40,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 841,
          "y" : 341
        },
        "to" : {
          "x" : 937,
          "y" : 357
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 57,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 822,
          "y" : 354
        },
        "to" : {
          "x" : 956,
          "y" : 555
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 9,
    "reactomeId" : 163088,
    "displayName" : "Telomerase RNP:G-strand telomeric chromosome end",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 511,
      "y" : 280
    },
    "minX" : 457,
    "maxX" : 571,
    "minY" : 243,
    "maxY" : 312,
    "prop" : {
      "x" : 457,
      "y" : 249,
      "width" : 108,
      "height" : 63
    },
    "textPosition" : {
      "x" : 463,
      "y" : 235
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 565,
          "y" : 249
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 565,
          "y" : 249
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 25,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 27,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 10,
    "reactomeId" : 30185,
    "displayName" : "dCTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 789,
      "y" : 373
    },
    "minX" : 705,
    "maxX" : 956,
    "minY" : 350,
    "maxY" : 555,
    "prop" : {
      "x" : 766,
      "y" : 360,
      "width" : 46,
      "height" : 27
    },
    "textPosition" : {
      "x" : 769,
      "y" : 363
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 807,
          "y" : 365
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 807,
          "y" : 365
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 21,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 763,
          "y" : 366
        },
        "to" : {
          "x" : 705,
          "y" : 350
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 23,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 793,
          "y" : 390
        },
        "to" : {
          "x" : 843,
          "y" : 521
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 40,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 815,
          "y" : 370
        },
        "to" : {
          "x" : 937,
          "y" : 357
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 57,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 801,
          "y" : 390
        },
        "to" : {
          "x" : 956,
          "y" : 555
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 11,
    "reactomeId" : 164684,
    "displayName" : "Telomerase Holoenzyme Base-paired to the Telomeric Chromosome End with an Additional single Stranded Telomere repeat",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 683,
      "y" : 655
    },
    "minX" : 596,
    "maxX" : 847,
    "minY" : 521,
    "maxY" : 695,
    "prop" : {
      "x" : 596,
      "y" : 616,
      "width" : 174,
      "height" : 79
    },
    "textPosition" : {
      "x" : 596,
      "y" : 604
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 770,
          "y" : 616
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 770,
          "y" : 616
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 23,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 730,
          "y" : 613
        },
        "to" : {
          "x" : 843,
          "y" : 521
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 23,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 754,
          "y" : 613
        },
        "to" : {
          "x" : 840,
          "y" : 568
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 843,
          "y" : 567
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 843,
          "y" : 567
        }
      }
    }, {
      "edgeId" : 24,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 12,
    "reactomeId" : 418325,
    "displayName" : "NHP2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 185,
      "y" : 515
    },
    "minX" : 163,
    "maxX" : 249,
    "minY" : 449,
    "maxY" : 526,
    "prop" : {
      "x" : 163,
      "y" : 504,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 164,
      "y" : 504
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 208,
          "y" : 504
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 208,
          "y" : 504
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 195,
          "y" : 501
        },
        "to" : {
          "x" : 249,
          "y" : 449
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 216,
            "y" : 469
          },
          "b" : {
            "x" : 228,
            "y" : 481
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 222,
            "y" : 475
          }
        }
      }
    } ]
  }, {
    "id" : 13,
    "reactomeId" : 418323,
    "displayName" : "RUVBL1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 374,
      "y" : 500
    },
    "minX" : 308,
    "maxX" : 412,
    "minY" : 405,
    "maxY" : 511,
    "prop" : {
      "x" : 342,
      "y" : 489,
      "width" : 64,
      "height" : 22
    },
    "textPosition" : {
      "x" : 346,
      "y" : 489
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 406,
          "y" : 489
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 406,
          "y" : 489
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 366,
          "y" : 486
        },
        "to" : {
          "x" : 308,
          "y" : 405
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 315,
          "y" : 408
        },
        "b" : {
          "x" : 308,
          "y" : 405
        },
        "c" : {
          "x" : 309,
          "y" : 413
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 309,
          "y" : 413
        }
      }
    } ]
  }, {
    "id" : 14,
    "reactomeId" : 418321,
    "displayName" : "RUVBL2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 304,
      "y" : 533
    },
    "minX" : 272,
    "maxX" : 342,
    "minY" : 407,
    "maxY" : 544,
    "prop" : {
      "x" : 272,
      "y" : 522,
      "width" : 64,
      "height" : 22
    },
    "textPosition" : {
      "x" : 276,
      "y" : 522
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 336,
          "y" : 522
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 336,
          "y" : 522
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 303,
          "y" : 519
        },
        "to" : {
          "x" : 303,
          "y" : 407
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 307,
          "y" : 414
        },
        "b" : {
          "x" : 303,
          "y" : 407
        },
        "c" : {
          "x" : 299,
          "y" : 414
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 299,
          "y" : 414
        }
      }
    } ]
  }, {
    "id" : 15,
    "reactomeId" : 163098,
    "displayName" : "Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 691,
      "y" : 498
    },
    "minX" : 605,
    "maxX" : 784,
    "minY" : 459,
    "maxY" : 532,
    "prop" : {
      "x" : 605,
      "y" : 465,
      "width" : 173,
      "height" : 67
    },
    "textPosition" : {
      "x" : 605,
      "y" : 455
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 778,
          "y" : 465
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 778,
          "y" : 465
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 21,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 24,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 16,
    "reactomeId" : 164683,
    "displayName" : "Telomerase RNP Bound and base-paired to the Telomeric Chromosome End",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 713,
      "y" : 288
    },
    "minX" : 649,
    "maxX" : 783,
    "minY" : 243,
    "maxY" : 389,
    "prop" : {
      "x" : 649,
      "y" : 249,
      "width" : 128,
      "height" : 78
    },
    "textPosition" : {
      "x" : 654,
      "y" : 250
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 777,
          "y" : 249
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 777,
          "y" : 249
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 21,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 707,
          "y" : 330
        },
        "to" : {
          "x" : 705,
          "y" : 350
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 21,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 685,
          "y" : 330
        },
        "to" : {
          "x" : 663,
          "y" : 360
        }
      }, {
        "from" : {
          "x" : 663,
          "y" : 360
        },
        "to" : {
          "x" : 692,
          "y" : 383
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 695,
          "y" : 385
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 695,
          "y" : 385
        }
      }
    }, {
      "edgeId" : 27,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 17,
    "reactomeId" : 164619,
    "displayName" : "Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 876,
      "y" : 644
    },
    "minX" : 737,
    "maxX" : 945,
    "minY" : 592,
    "maxY" : 742,
    "prop" : {
      "x" : 814,
      "y" : 598,
      "width" : 125,
      "height" : 93
    },
    "textPosition" : {
      "x" : 812,
      "y" : 586
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 939,
          "y" : 598
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 939,
          "y" : 598
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 23,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 3803,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 811,
          "y" : 688
        },
        "to" : {
          "x" : 737,
          "y" : 742
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 18,
    "reactomeId" : 29604,
    "displayName" : "dATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 760,
      "y" : 411
    },
    "minX" : 705,
    "maxX" : 956,
    "minY" : 350,
    "maxY" : 555,
    "prop" : {
      "x" : 737,
      "y" : 396,
      "width" : 46,
      "height" : 30
    },
    "textPosition" : {
      "x" : 740,
      "y" : 400
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 778,
          "y" : 401
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 778,
          "y" : 401
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 21,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 746,
          "y" : 393
        },
        "to" : {
          "x" : 705,
          "y" : 350
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 23,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 771,
          "y" : 429
        },
        "to" : {
          "x" : 843,
          "y" : 521
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 40,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 786,
          "y" : 403
        },
        "to" : {
          "x" : 937,
          "y" : 357
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 57,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 780,
          "y" : 429
        },
        "to" : {
          "x" : 956,
          "y" : 555
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 20,
    "reactomeId" : 163101,
    "displayName" : "Telomerase RNP",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 359,
      "y" : 327
    },
    "minX" : 301,
    "maxX" : 505,
    "minY" : 277,
    "maxY" : 522,
    "prop" : {
      "x" : 301,
      "y" : 316,
      "width" : 117,
      "height" : 22
    },
    "textPosition" : {
      "x" : 304,
      "y" : 317
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 418,
          "y" : 316
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 418,
          "y" : 316
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 25,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 364,
          "y" : 313
        },
        "to" : {
          "x" : 385,
          "y" : 277
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 26,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 3803,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 367,
          "y" : 341
        },
        "to" : {
          "x" : 505,
          "y" : 522
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 374,
          "y" : 344
        },
        "b" : {
          "x" : 367,
          "y" : 341
        },
        "c" : {
          "x" : 368,
          "y" : 349
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 368,
          "y" : 349
        }
      }
    } ]
  }, {
    "id" : 1560,
    "reactomeId" : 9668898,
    "displayName" : "CHTF8",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1200,
      "y" : 167
    },
    "minX" : 1173,
    "maxX" : 1280,
    "minY" : 150,
    "maxY" : 178,
    "prop" : {
      "x" : 1173,
      "y" : 156,
      "width" : 55,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1177,
      "y" : 156
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1228,
          "y" : 156
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1228,
          "y" : 156
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 1559,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1231,
          "y" : 165
        },
        "to" : {
          "x" : 1280,
          "y" : 163
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 1561,
    "reactomeId" : 9668906,
    "displayName" : "CHTF18",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1218,
      "y" : 125
    },
    "minX" : 1186,
    "maxX" : 1280,
    "minY" : 108,
    "maxY" : 163,
    "prop" : {
      "x" : 1186,
      "y" : 114,
      "width" : 64,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1190,
      "y" : 114
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1250,
          "y" : 114
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1250,
          "y" : 114
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 1559,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1235,
          "y" : 139
        },
        "to" : {
          "x" : 1280,
          "y" : 163
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 1562,
    "reactomeId" : 9668907,
    "displayName" : "DSCC1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1293,
      "y" : 114
    },
    "minX" : 1266,
    "maxX" : 1327,
    "minY" : 97,
    "maxY" : 163,
    "prop" : {
      "x" : 1266,
      "y" : 103,
      "width" : 55,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1269,
      "y" : 103
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1321,
          "y" : 103
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1321,
          "y" : 103
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 1559,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1290,
          "y" : 128
        },
        "to" : {
          "x" : 1280,
          "y" : 163
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 1563,
    "reactomeId" : 9668900,
    "displayName" : "CTF18 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1403,
      "y" : 172
    },
    "minX" : 1341,
    "maxX" : 1575,
    "minY" : 155,
    "maxY" : 214,
    "prop" : {
      "x" : 1341,
      "y" : 161,
      "width" : 124,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1352,
      "y" : 162
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1465,
          "y" : 161
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1465,
          "y" : 161
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 1559,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 1564,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1448,
          "y" : 186
        },
        "to" : {
          "x" : 1575,
          "y" : 214
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3867,
    "reactomeId" : 113518,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 121,
      "y" : 273
    },
    "minX" : 101,
    "maxX" : 167,
    "minY" : 245,
    "maxY" : 286,
    "prop" : {
      "x" : 101,
      "y" : 260,
      "width" : 41,
      "height" : 26
    },
    "textPosition" : {
      "x" : 104,
      "y" : 262
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 137,
          "y" : 265
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 137,
          "y" : 265
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3866,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 145,
          "y" : 260
        },
        "to" : {
          "x" : 167,
          "y" : 245
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 3868,
    "reactomeId" : 9686572,
    "displayName" : "PP6-PPP6R3",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 230,
      "y" : 327
    },
    "minX" : 188,
    "maxX" : 410,
    "minY" : 249,
    "maxY" : 338,
    "prop" : {
      "x" : 188,
      "y" : 316,
      "width" : 84,
      "height" : 22
    },
    "textPosition" : {
      "x" : 188,
      "y" : 317
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 272,
          "y" : 316
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 272,
          "y" : 316
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 25,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 252,
          "y" : 313
        },
        "to" : {
          "x" : 393,
          "y" : 249
        }
      }, {
        "from" : {
          "x" : 393,
          "y" : 249
        },
        "to" : {
          "x" : 410,
          "y" : 270
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 403,
          "y" : 267
        },
        "b" : {
          "x" : 410,
          "y" : 270
        },
        "c" : {
          "x" : 409,
          "y" : 262
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 409,
          "y" : 262
        }
      }
    }, {
      "edgeId" : 3866,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 229,
          "y" : 313
        },
        "to" : {
          "x" : 227,
          "y" : 261
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 227,
          "y" : 257
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 227,
          "y" : 257
        }
      }
    } ]
  }, {
    "id" : 28,
    "reactomeId" : 68450,
    "displayName" : "DNA Polymerase delta tetramer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1457,
      "y" : 572
    },
    "minX" : 1348,
    "maxX" : 1563,
    "minY" : 548,
    "maxY" : 612,
    "prop" : {
      "x" : 1391,
      "y" : 554,
      "width" : 133,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1400,
      "y" : 555
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1524,
          "y" : 554
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1524,
          "y" : 554
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 32,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1407,
          "y" : 593
        },
        "to" : {
          "x" : 1348,
          "y" : 612
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1402,
          "y" : 599
        },
        "b" : {
          "x" : 1407,
          "y" : 593
        },
        "c" : {
          "x" : 1399,
          "y" : 591
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1399,
          "y" : 591
        }
      }
    }, {
      "edgeId" : 50,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1527,
          "y" : 572
        },
        "to" : {
          "x" : 1563,
          "y" : 573
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 1565,
    "reactomeId" : 68429,
    "displayName" : "RFC4",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1635,
      "y" : 120
    },
    "minX" : 1575,
    "maxX" : 1664,
    "minY" : 103,
    "maxY" : 214,
    "prop" : {
      "x" : 1613,
      "y" : 109,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1616,
      "y" : 109
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1658,
          "y" : 109
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1658,
          "y" : 109
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 1564,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1627,
          "y" : 134
        },
        "to" : {
          "x" : 1575,
          "y" : 214
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3870,
    "reactomeId" : 113550,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 272,
      "y" : 281
    },
    "minX" : 257,
    "maxX" : 288,
    "minY" : 244,
    "maxY" : 292,
    "prop" : {
      "x" : 257,
      "y" : 271,
      "width" : 30,
      "height" : 21
    },
    "textPosition" : {
      "x" : 262,
      "y" : 271
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 282,
          "y" : 276
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 282,
          "y" : 276
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3866,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 269,
          "y" : 268
        },
        "to" : {
          "x" : 263,
          "y" : 244
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 263,
          "y" : 262
        },
        "b" : {
          "x" : 269,
          "y" : 268
        },
        "c" : {
          "x" : 271,
          "y" : 260
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 271,
          "y" : 260
        }
      }
    } ]
  }, {
    "id" : 1566,
    "reactomeId" : 68427,
    "displayName" : "RFC5",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1691,
      "y" : 138
    },
    "minX" : 1575,
    "maxX" : 1720,
    "minY" : 121,
    "maxY" : 214,
    "prop" : {
      "x" : 1669,
      "y" : 127,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1672,
      "y" : 127
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1714,
          "y" : 127
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1714,
          "y" : 127
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 1564,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1674,
          "y" : 152
        },
        "to" : {
          "x" : 1575,
          "y" : 214
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 30,
    "reactomeId" : 68440,
    "displayName" : "PCNA homotrimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1632,
      "y" : 650
    },
    "minX" : 1348,
    "maxX" : 1684,
    "minY" : 561,
    "maxY" : 668,
    "prop" : {
      "x" : 1586,
      "y" : 632,
      "width" : 92,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1592,
      "y" : 633
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1678,
          "y" : 632
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1678,
          "y" : 632
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 32,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1583,
          "y" : 643
        },
        "to" : {
          "x" : 1348,
          "y" : 612
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1576,
          "y" : 646
        },
        "b" : {
          "x" : 1583,
          "y" : 643
        },
        "c" : {
          "x" : 1577,
          "y" : 638
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1577,
          "y" : 638
        }
      }
    }, {
      "edgeId" : 48,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1638,
          "y" : 629
        },
        "to" : {
          "x" : 1664,
          "y" : 561
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 31,
    "reactomeId" : 176394,
    "displayName" : "Processive complex loaded on telomere:ligated C-strand Okazaki fragments",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1149,
      "y" : 680
    },
    "minX" : 1086,
    "maxX" : 1219,
    "minY" : 643,
    "maxY" : 711,
    "prop" : {
      "x" : 1086,
      "y" : 649,
      "width" : 127,
      "height" : 62
    },
    "textPosition" : {
      "x" : 1085,
      "y" : 634
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1213,
          "y" : 649
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1213,
          "y" : 649
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 32,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 56,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3871,
    "reactomeId" : 9690022,
    "displayName" : "Extended And Processed Telomere End",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1477,
      "y" : 692
    },
    "minX" : 1292,
    "maxX" : 1560,
    "minY" : 612,
    "maxY" : 797,
    "prop" : {
      "x" : 1400,
      "y" : 670,
      "width" : 154,
      "height" : 44
    },
    "textPosition" : {
      "x" : 1407,
      "y" : 665
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1554,
          "y" : 670
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1554,
          "y" : 670
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 79,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1438,
          "y" : 717
        },
        "to" : {
          "x" : 1292,
          "y" : 797
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 32,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1441,
          "y" : 667
        },
        "to" : {
          "x" : 1348,
          "y" : 612
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1433,
          "y" : 667
        },
        "b" : {
          "x" : 1441,
          "y" : 667
        },
        "c" : {
          "x" : 1437,
          "y" : 660
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1437,
          "y" : 660
        }
      }
    } ]
  }, {
    "id" : 1567,
    "reactomeId" : 68433,
    "displayName" : "RFC2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1516,
      "y" : 119
    },
    "minX" : 1494,
    "maxX" : 1575,
    "minY" : 102,
    "maxY" : 214,
    "prop" : {
      "x" : 1494,
      "y" : 108,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1497,
      "y" : 108
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1539,
          "y" : 108
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1539,
          "y" : 108
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 1564,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1522,
          "y" : 133
        },
        "to" : {
          "x" : 1575,
          "y" : 214
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 1568,
    "reactomeId" : 68431,
    "displayName" : "RFC3",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1573,
      "y" : 116
    },
    "minX" : 1551,
    "maxX" : 1602,
    "minY" : 99,
    "maxY" : 214,
    "prop" : {
      "x" : 1551,
      "y" : 105,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1554,
      "y" : 105
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1596,
          "y" : 105
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1596,
          "y" : 105
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 1564,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1573,
          "y" : 130
        },
        "to" : {
          "x" : 1575,
          "y" : 214
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3872,
    "reactomeId" : 9757634,
    "displayName" : "NTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 889,
      "y" : 243
    },
    "minX" : 869,
    "maxX" : 911,
    "minY" : 199,
    "maxY" : 259,
    "prop" : {
      "x" : 869,
      "y" : 228,
      "width" : 41,
      "height" : 31
    },
    "textPosition" : {
      "x" : 873,
      "y" : 233
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 905,
          "y" : 233
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 905,
          "y" : 233
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 39,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 892,
          "y" : 225
        },
        "to" : {
          "x" : 899,
          "y" : 199
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3616,
    "reactomeId" : 9671152,
    "displayName" : "SHQ1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 152,
      "y" : 821
    },
    "minX" : 128,
    "maxX" : 182,
    "minY" : 735,
    "maxY" : 832,
    "prop" : {
      "x" : 128,
      "y" : 810,
      "width" : 48,
      "height" : 22
    },
    "textPosition" : {
      "x" : 131,
      "y" : 810
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 176,
          "y" : 810
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 176,
          "y" : 810
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3615,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 152,
          "y" : 807
        },
        "to" : {
          "x" : 154,
          "y" : 735
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 1569,
    "reactomeId" : 9668901,
    "displayName" : "CTF18-RFC(7s) complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1217,
      "y" : 262
    },
    "minX" : 1169,
    "maxX" : 1271,
    "minY" : 238,
    "maxY" : 280,
    "prop" : {
      "x" : 1169,
      "y" : 244,
      "width" : 96,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1173,
      "y" : 245
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1265,
          "y" : 244
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1265,
          "y" : 244
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 1564,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 33,
    "reactomeId" : 174433,
    "displayName" : "RNA primer:DNA primer:G-strand extended telomere:POLA:primase",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1026,
      "y" : 473
    },
    "minX" : 962,
    "maxX" : 1207,
    "minY" : 428,
    "maxY" : 512,
    "prop" : {
      "x" : 962,
      "y" : 434,
      "width" : 128,
      "height" : 78
    },
    "textPosition" : {
      "x" : 970,
      "y" : 435
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1090,
          "y" : 434
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1090,
          "y" : 434
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 40,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 49,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1093,
          "y" : 472
        },
        "to" : {
          "x" : 1207,
          "y" : 471
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3617,
    "reactomeId" : 9671148,
    "displayName" : "DKC1:SHQ1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 287,
      "y" : 699
    },
    "minX" : 244,
    "maxX" : 336,
    "minY" : 682,
    "maxY" : 710,
    "prop" : {
      "x" : 244,
      "y" : 688,
      "width" : 86,
      "height" : 22
    },
    "textPosition" : {
      "x" : 248,
      "y" : 689
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 330,
          "y" : 688
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 330,
          "y" : 688
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3615,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 37,
    "reactomeId" : 68507,
    "displayName" : "DNA polymerase alpha:primase",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 501,
      "y" : 101
    },
    "minX" : 435,
    "maxX" : 1209,
    "minY" : 77,
    "maxY" : 527,
    "prop" : {
      "x" : 435,
      "y" : 83,
      "width" : 133,
      "height" : 36
    },
    "textPosition" : {
      "x" : 444,
      "y" : 84
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 568,
          "y" : 83
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 568,
          "y" : 83
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 422,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 522,
          "y" : 122
        },
        "to" : {
          "x" : 604,
          "y" : 187
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 49,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 571,
          "y" : 101
        },
        "to" : {
          "x" : 1141,
          "y" : 108
        }
      }, {
        "from" : {
          "x" : 1141,
          "y" : 108
        },
        "to" : {
          "x" : 1154,
          "y" : 526
        }
      }, {
        "from" : {
          "x" : 1154,
          "y" : 526
        },
        "to" : {
          "x" : 1209,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 578,
          "y" : 97
        },
        "b" : {
          "x" : 571,
          "y" : 101
        },
        "c" : {
          "x" : 578,
          "y" : 105
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 578,
          "y" : 105
        }
      }
    } ]
  }, {
    "id" : 38,
    "reactomeId" : 174434,
    "displayName" : "RNA primer:G-strand extended telomere end:POLA:primase",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1029,
      "y" : 251
    },
    "minX" : 937,
    "maxX" : 1102,
    "minY" : 218,
    "maxY" : 382,
    "prop" : {
      "x" : 962,
      "y" : 224,
      "width" : 134,
      "height" : 54
    },
    "textPosition" : {
      "x" : 963,
      "y" : 215
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1096,
          "y" : 224
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1096,
          "y" : 224
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 39,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 40,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1005,
          "y" : 281
        },
        "to" : {
          "x" : 937,
          "y" : 357
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 40,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1015,
          "y" : 281
        },
        "to" : {
          "x" : 968,
          "y" : 375
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 966,
          "y" : 378
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 966,
          "y" : 378
        }
      }
    } ]
  }, {
    "id" : 42,
    "reactomeId" : 174453,
    "displayName" : "Processive complex loaded on telomere",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1086,
      "y" : 589
    },
    "minX" : 956,
    "maxX" : 1159,
    "minY" : 555,
    "maxY" : 632,
    "prop" : {
      "x" : 1020,
      "y" : 564,
      "width" : 133,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1020,
      "y" : 579
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1153,
          "y" : 564
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1153,
          "y" : 564
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 57,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1017,
          "y" : 571
        },
        "to" : {
          "x" : 956,
          "y" : 555
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 57,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1045,
          "y" : 617
        },
        "to" : {
          "x" : 1016,
          "y" : 632
        }
      }, {
        "from" : {
          "x" : 1016,
          "y" : 632
        },
        "to" : {
          "x" : 991,
          "y" : 628
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 987,
          "y" : 628
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 987,
          "y" : 628
        }
      }
    } ]
  }, {
    "id" : 43,
    "reactomeId" : 174449,
    "displayName" : "RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1368,
      "y" : 290
    },
    "minX" : 1291,
    "maxX" : 1660,
    "minY" : 240,
    "maxY" : 435,
    "prop" : {
      "x" : 1291,
      "y" : 246,
      "width" : 154,
      "height" : 89
    },
    "textPosition" : {
      "x" : 1296,
      "y" : 244
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1445,
          "y" : 246
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1445,
          "y" : 246
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 48,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1448,
          "y" : 290
        },
        "to" : {
          "x" : 1636,
          "y" : 291
        }
      }, {
        "from" : {
          "x" : 1636,
          "y" : 291
        },
        "to" : {
          "x" : 1660,
          "y" : 435
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1455,
          "y" : 286
        },
        "b" : {
          "x" : 1448,
          "y" : 290
        },
        "c" : {
          "x" : 1455,
          "y" : 294
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1455,
          "y" : 294
        }
      }
    }, {
      "edgeId" : 51,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 44,
    "reactomeId" : 174450,
    "displayName" : "RNA primer-DNA primer:G-strand extended telomere:PCNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1558,
      "y" : 457
    },
    "minX" : 1494,
    "maxX" : 1628,
    "minY" : 373,
    "maxY" : 573,
    "prop" : {
      "x" : 1494,
      "y" : 425,
      "width" : 128,
      "height" : 64
    },
    "textPosition" : {
      "x" : 1502,
      "y" : 426
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1622,
          "y" : 425
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1622,
          "y" : 425
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 50,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1559,
          "y" : 492
        },
        "to" : {
          "x" : 1563,
          "y" : 573
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 51,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1557,
          "y" : 422
        },
        "to" : {
          "x" : 1556,
          "y" : 373
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1553,
          "y" : 415
        },
        "b" : {
          "x" : 1557,
          "y" : 422
        },
        "c" : {
          "x" : 1561,
          "y" : 415
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1561,
          "y" : 415
        }
      }
    } ]
  }, {
    "id" : 46,
    "reactomeId" : 174454,
    "displayName" : "RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1310,
      "y" : 526
    },
    "minX" : 1209,
    "maxX" : 1664,
    "minY" : 475,
    "maxY" : 571,
    "prop" : {
      "x" : 1246,
      "y" : 481,
      "width" : 128,
      "height" : 90
    },
    "textPosition" : {
      "x" : 1245,
      "y" : 480
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1374,
          "y" : 481
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1374,
          "y" : 481
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 48,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1377,
          "y" : 532
        },
        "to" : {
          "x" : 1664,
          "y" : 561
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 48,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1377,
          "y" : 524
        },
        "to" : {
          "x" : 1643,
          "y" : 517
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1647,
          "y" : 517
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1647,
          "y" : 517
        }
      }
    }, {
      "edgeId" : 49,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1243,
          "y" : 526
        },
        "to" : {
          "x" : 1209,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1236,
          "y" : 530
        },
        "b" : {
          "x" : 1243,
          "y" : 526
        },
        "c" : {
          "x" : 1236,
          "y" : 522
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1236,
          "y" : 522
        }
      }
    } ]
  }, {
    "id" : 52,
    "reactomeId" : 174431,
    "displayName" : "Processive complex loaded on telomere:Okazaki fragment:Flap",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 708,
      "y" : 856
    },
    "minX" : 642,
    "maxX" : 855,
    "minY" : 817,
    "maxY" : 981,
    "prop" : {
      "x" : 642,
      "y" : 823,
      "width" : 133,
      "height" : 66
    },
    "textPosition" : {
      "x" : 642,
      "y" : 826
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 775,
          "y" : 823
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 775,
          "y" : 823
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 71,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 710,
          "y" : 892
        },
        "to" : {
          "x" : 718,
          "y" : 981
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 58,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 778,
          "y" : 853
        },
        "to" : {
          "x" : 855,
          "y" : 850
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 785,
          "y" : 849
        },
        "b" : {
          "x" : 778,
          "y" : 853
        },
        "c" : {
          "x" : 785,
          "y" : 857
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 785,
          "y" : 857
        }
      }
    } ]
  }, {
    "id" : 53,
    "reactomeId" : 174435,
    "displayName" : "Processive complex loaded on telomere:Okazaki fragment complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 998,
      "y" : 738
    },
    "minX" : 932,
    "maxX" : 1071,
    "minY" : 700,
    "maxY" : 810,
    "prop" : {
      "x" : 932,
      "y" : 706,
      "width" : 133,
      "height" : 64
    },
    "textPosition" : {
      "x" : 932,
      "y" : 707
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1065,
          "y" : 706
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1065,
          "y" : 706
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 57,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 58,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 986,
          "y" : 773
        },
        "to" : {
          "x" : 971,
          "y" : 810
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 2614,
    "reactomeId" : 212295,
    "displayName" : "H3F3A",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1843,
      "y" : 877
    },
    "minX" : 1816,
    "maxX" : 1911,
    "minY" : 860,
    "maxY" : 888,
    "prop" : {
      "x" : 1816,
      "y" : 866,
      "width" : 55,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1819,
      "y" : 866
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1871,
          "y" : 866
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1871,
          "y" : 866
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2627,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1874,
          "y" : 878
        },
        "to" : {
          "x" : 1911,
          "y" : 880
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1886,
            "y" : 873
          },
          "b" : {
            "x" : 1898,
            "y" : 885
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1892,
            "y" : 879
          }
        }
      }
    } ]
  }, {
    "id" : 1590,
    "reactomeId" : 9668941,
    "displayName" : "RFC,(CFT18-RFC)",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 1228,
      "y" : 409
    },
    "minX" : 1173,
    "maxX" : 1556,
    "minY" : 373,
    "maxY" : 471,
    "prop" : {
      "x" : 1173,
      "y" : 396,
      "width" : 110,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1173,
      "y" : 399
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "fgColor" : {
      "r" : 0,
      "g" : 0,
      "b" : 0
    },
    "connectors" : [ {
      "edgeId" : 49,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1223,
          "y" : 429
        },
        "to" : {
          "x" : 1207,
          "y" : 471
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 51,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1289,
          "y" : 402
        },
        "to" : {
          "x" : 1556,
          "y" : 373
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1295,
          "y" : 397
        },
        "b" : {
          "x" : 1289,
          "y" : 402
        },
        "c" : {
          "x" : 1296,
          "y" : 405
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1296,
          "y" : 405
        }
      }
    } ]
  }, {
    "id" : 54,
    "reactomeId" : 174432,
    "displayName" : "Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1166,
      "y" : 844
    },
    "minX" : 1084,
    "maxX" : 1255,
    "minY" : 804,
    "maxY" : 878,
    "prop" : {
      "x" : 1084,
      "y" : 810,
      "width" : 165,
      "height" : 68
    },
    "textPosition" : {
      "x" : 1099,
      "y" : 801
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1249,
          "y" : 810
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1249,
          "y" : 810
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 70,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 56,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 2615,
    "reactomeId" : 9670122,
    "displayName" : "Telomere:Shelterin:Nucleosome (H3F3A):ATRX:DAXX",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1922,
      "y" : 1019
    },
    "minX" : 1867,
    "maxX" : 1983,
    "minY" : 941,
    "maxY" : 1110,
    "prop" : {
      "x" : 1867,
      "y" : 980,
      "width" : 110,
      "height" : 78
    },
    "textPosition" : {
      "x" : 1874,
      "y" : 981
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1977,
          "y" : 980
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1977,
          "y" : 980
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2627,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1919,
          "y" : 977
        },
        "to" : {
          "x" : 1916,
          "y" : 941
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1914,
          "y" : 970
        },
        "b" : {
          "x" : 1919,
          "y" : 977
        },
        "c" : {
          "x" : 1922,
          "y" : 970
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1922,
          "y" : 970
        }
      }
    }, {
      "edgeId" : 2772,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 1922,
          "y" : 1061
        },
        "to" : {
          "x" : 1924,
          "y" : 1110
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1920,
          "y" : 1110
        },
        "b" : {
          "x" : 1928,
          "y" : 1110
        },
        "c" : {
          "x" : 1924,
          "y" : 1110
        },
        "type" : "STOP",
        "centre" : {
          "x" : 1924,
          "y" : 1110
        }
      }
    } ]
  }, {
    "id" : 2616,
    "reactomeId" : 181914,
    "displayName" : "HIST3H3",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1832,
      "y" : 950
    },
    "minX" : 1798,
    "maxX" : 1916,
    "minY" : 933,
    "maxY" : 961,
    "prop" : {
      "x" : 1798,
      "y" : 939,
      "width" : 68,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1802,
      "y" : 939
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1866,
          "y" : 939
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1866,
          "y" : 939
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2627,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1869,
          "y" : 946
        },
        "to" : {
          "x" : 1916,
          "y" : 941
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 1886,
            "y" : 937
          },
          "b" : {
            "x" : 1898,
            "y" : 949
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1892,
            "y" : 943
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1875,
          "y" : 941
        },
        "b" : {
          "x" : 1869,
          "y" : 946
        },
        "c" : {
          "x" : 1876,
          "y" : 949
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1876,
          "y" : 949
        }
      }
    } ]
  }, {
    "id" : 59,
    "reactomeId" : 29626,
    "displayName" : "GMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1335,
      "y" : 943
    },
    "minX" : 1149,
    "maxX" : 1361,
    "minY" : 927,
    "maxY" : 961,
    "prop" : {
      "x" : 1311,
      "y" : 928,
      "width" : 49,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1318,
      "y" : 932
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1355,
          "y" : 933
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1355,
          "y" : 933
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 69,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1308,
          "y" : 945
        },
        "to" : {
          "x" : 1149,
          "y" : 961
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1302,
          "y" : 950
        },
        "b" : {
          "x" : 1308,
          "y" : 945
        },
        "c" : {
          "x" : 1301,
          "y" : 942
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1301,
          "y" : 942
        }
      }
    } ]
  }, {
    "id" : 60,
    "reactomeId" : 418076,
    "displayName" : "CMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1385,
      "y" : 1002
    },
    "minX" : 1149,
    "maxX" : 1411,
    "minY" : 961,
    "maxY" : 1017,
    "prop" : {
      "x" : 1361,
      "y" : 987,
      "width" : 49,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1368,
      "y" : 991
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1405,
          "y" : 992
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1405,
          "y" : 992
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 69,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1358,
          "y" : 997
        },
        "to" : {
          "x" : 1149,
          "y" : 961
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1350,
          "y" : 1000
        },
        "b" : {
          "x" : 1358,
          "y" : 997
        },
        "c" : {
          "x" : 1352,
          "y" : 992
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1352,
          "y" : 992
        }
      }
    } ]
  }, {
    "id" : 61,
    "reactomeId" : 174442,
    "displayName" : "Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1130,
      "y" : 1077
    },
    "minX" : 1064,
    "maxX" : 1203,
    "minY" : 993,
    "maxY" : 1118,
    "prop" : {
      "x" : 1064,
      "y" : 1037,
      "width" : 133,
      "height" : 81
    },
    "textPosition" : {
      "x" : 1064,
      "y" : 1041
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1197,
          "y" : 1037
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1197,
          "y" : 1037
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 69,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 69,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1159,
          "y" : 1034
        },
        "to" : {
          "x" : 1178,
          "y" : 1012
        }
      }, {
        "from" : {
          "x" : 1178,
          "y" : 1012
        },
        "to" : {
          "x" : 1155,
          "y" : 999
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1151,
          "y" : 997
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1151,
          "y" : 997
        }
      }
    }, {
      "edgeId" : 72,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 2366,
    "reactomeId" : 3222068,
    "displayName" : "DAXX",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1917,
      "y" : 594
    },
    "minX" : 1812,
    "maxX" : 1946,
    "minY" : 577,
    "maxY" : 616,
    "prop" : {
      "x" : 1895,
      "y" : 583,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1898,
      "y" : 583
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1940,
          "y" : 583
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1940,
          "y" : 583
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2489,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1892,
          "y" : 598
        },
        "to" : {
          "x" : 1812,
          "y" : 616
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 62,
    "reactomeId" : 174436,
    "displayName" : "Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 954,
      "y" : 1076
    },
    "minX" : 888,
    "maxX" : 1027,
    "minY" : 1029,
    "maxY" : 1165,
    "prop" : {
      "x" : 888,
      "y" : 1035,
      "width" : 133,
      "height" : 82
    },
    "textPosition" : {
      "x" : 888,
      "y" : 1040
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1021,
          "y" : 1035
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1021,
          "y" : 1035
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 71,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 72,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 955,
          "y" : 1120
        },
        "to" : {
          "x" : 958,
          "y" : 1165
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 2367,
    "reactomeId" : 9007919,
    "displayName" : "ATRX",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1827,
      "y" : 576
    },
    "minX" : 1805,
    "maxX" : 1856,
    "minY" : 559,
    "maxY" : 616,
    "prop" : {
      "x" : 1805,
      "y" : 565,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1808,
      "y" : 565
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1850,
          "y" : 565
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1850,
          "y" : 565
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2489,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1822,
          "y" : 590
        },
        "to" : {
          "x" : 1812,
          "y" : 616
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 63,
    "reactomeId" : 68462,
    "displayName" : "RPA heterotrimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 988,
      "y" : 979
    },
    "minX" : 718,
    "maxX" : 1149,
    "minY" : 961,
    "maxY" : 990,
    "prop" : {
      "x" : 924,
      "y" : 968,
      "width" : 128,
      "height" : 22
    },
    "textPosition" : {
      "x" : 930,
      "y" : 969
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1052,
          "y" : 968
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1052,
          "y" : 968
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 69,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1055,
          "y" : 971
        },
        "to" : {
          "x" : 1149,
          "y" : 961
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1061,
          "y" : 966
        },
        "b" : {
          "x" : 1055,
          "y" : 971
        },
        "c" : {
          "x" : 1062,
          "y" : 974
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1062,
          "y" : 974
        }
      }
    }, {
      "edgeId" : 71,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 921,
          "y" : 979
        },
        "to" : {
          "x" : 718,
          "y" : 981
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 64,
    "reactomeId" : 418075,
    "displayName" : "UMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1384,
      "y" : 1060
    },
    "minX" : 1149,
    "maxX" : 1410,
    "minY" : 961,
    "maxY" : 1075,
    "prop" : {
      "x" : 1360,
      "y" : 1045,
      "width" : 49,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1367,
      "y" : 1049
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1404,
          "y" : 1050
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1404,
          "y" : 1050
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 69,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1357,
          "y" : 1049
        },
        "to" : {
          "x" : 1149,
          "y" : 961
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1349,
          "y" : 1050
        },
        "b" : {
          "x" : 1357,
          "y" : 1049
        },
        "c" : {
          "x" : 1352,
          "y" : 1043
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1352,
          "y" : 1043
        }
      }
    } ]
  }, {
    "id" : 2368,
    "reactomeId" : 9007927,
    "displayName" : "ATRX:DAXX",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1752,
      "y" : 730
    },
    "minX" : 1709,
    "maxX" : 2017,
    "minY" : 713,
    "maxY" : 912,
    "prop" : {
      "x" : 1709,
      "y" : 719,
      "width" : 87,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1716,
      "y" : 720
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1796,
          "y" : 719
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1796,
          "y" : 719
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2627,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 1799,
          "y" : 730
        },
        "to" : {
          "x" : 2010,
          "y" : 733
        }
      }, {
        "from" : {
          "x" : 2010,
          "y" : 733
        },
        "to" : {
          "x" : 2017,
          "y" : 906
        }
      }, {
        "from" : {
          "x" : 2017,
          "y" : 906
        },
        "to" : {
          "x" : 1922,
          "y" : 908
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1929,
          "y" : 904
        },
        "b" : {
          "x" : 1922,
          "y" : 908
        },
        "c" : {
          "x" : 1929,
          "y" : 912
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 1929,
          "y" : 912
        }
      }
    }, {
      "edgeId" : 2489,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 2490,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1750,
          "y" : 744
        },
        "to" : {
          "x" : 1736,
          "y" : 823
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 65,
    "reactomeId" : 174440,
    "displayName" : "Processive complex loaded on telomere:Okazaki fragments:Remaining Flap",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 984,
      "y" : 918
    },
    "minX" : 918,
    "maxX" : 1149,
    "minY" : 880,
    "maxY" : 961,
    "prop" : {
      "x" : 918,
      "y" : 886,
      "width" : 132,
      "height" : 64
    },
    "textPosition" : {
      "x" : 917,
      "y" : 873
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1050,
          "y" : 886
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1050,
          "y" : 886
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 69,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1053,
          "y" : 935
        },
        "to" : {
          "x" : 1149,
          "y" : 961
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1061,
          "y" : 933
        },
        "b" : {
          "x" : 1053,
          "y" : 935
        },
        "c" : {
          "x" : 1059,
          "y" : 941
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1059,
          "y" : 941
        }
      }
    }, {
      "edgeId" : 70,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 66,
    "reactomeId" : 164121,
    "displayName" : "AMP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1285,
      "y" : 1059
    },
    "minX" : 1149,
    "maxX" : 1311,
    "minY" : 961,
    "maxY" : 1074,
    "prop" : {
      "x" : 1261,
      "y" : 1044,
      "width" : 49,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1268,
      "y" : 1048
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1305,
          "y" : 1049
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1305,
          "y" : 1049
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 69,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1264,
          "y" : 1041
        },
        "to" : {
          "x" : 1149,
          "y" : 961
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1256,
          "y" : 1040
        },
        "b" : {
          "x" : 1264,
          "y" : 1041
        },
        "c" : {
          "x" : 1261,
          "y" : 1034
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1261,
          "y" : 1034
        }
      }
    } ]
  }, {
    "id" : 67,
    "reactomeId" : 68465,
    "displayName" : "DNA2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 960,
      "y" : 1242
    },
    "minX" : 938,
    "maxX" : 1219,
    "minY" : 961,
    "maxY" : 1253,
    "prop" : {
      "x" : 938,
      "y" : 1231,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 939,
      "y" : 1231
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 983,
          "y" : 1231
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 983,
          "y" : 1231
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 69,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 986,
          "y" : 1235
        },
        "to" : {
          "x" : 1219,
          "y" : 1162
        }
      }, {
        "from" : {
          "x" : 1219,
          "y" : 1162
        },
        "to" : {
          "x" : 1211,
          "y" : 1020
        }
      }, {
        "from" : {
          "x" : 1211,
          "y" : 1020
        },
        "to" : {
          "x" : 1149,
          "y" : 961
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 991,
          "y" : 1229
        },
        "b" : {
          "x" : 986,
          "y" : 1235
        },
        "c" : {
          "x" : 994,
          "y" : 1237
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 994,
          "y" : 1237
        }
      }
    }, {
      "edgeId" : 72,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 959,
          "y" : 1228
        },
        "to" : {
          "x" : 958,
          "y" : 1165
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 580,
    "reactomeId" : 9668821,
    "displayName" : "STN1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 93,
      "y" : 79
    },
    "minX" : 71,
    "maxX" : 196,
    "minY" : 62,
    "maxY" : 90,
    "prop" : {
      "x" : 71,
      "y" : 68,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 73,
      "y" : 68
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 116,
          "y" : 68
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 116,
          "y" : 68
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 579,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 119,
          "y" : 76
        },
        "to" : {
          "x" : 196,
          "y" : 68
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 68,
    "reactomeId" : 54745,
    "displayName" : "FEN1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1219,
      "y" : 928
    },
    "minX" : 1108,
    "maxX" : 1248,
    "minY" : 911,
    "maxY" : 939,
    "prop" : {
      "x" : 1197,
      "y" : 917,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1199,
      "y" : 917
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1242,
          "y" : 917
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1242,
          "y" : 917
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 70,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1194,
          "y" : 927
        },
        "to" : {
          "x" : 1116,
          "y" : 925
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1112,
          "y" : 924
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1112,
          "y" : 924
        }
      }
    } ]
  }, {
    "id" : 581,
    "reactomeId" : 9668823,
    "displayName" : "TEN1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 141,
      "y" : 37
    },
    "minX" : 119,
    "maxX" : 196,
    "minY" : 20,
    "maxY" : 68,
    "prop" : {
      "x" : 119,
      "y" : 26,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 121,
      "y" : 26
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 164,
          "y" : 26
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 164,
          "y" : 26
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 579,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 160,
          "y" : 51
        },
        "to" : {
          "x" : 196,
          "y" : 68
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 582,
    "reactomeId" : 9668825,
    "displayName" : "CTC1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 92,
      "y" : 120
    },
    "minX" : 70,
    "maxX" : 196,
    "minY" : 68,
    "maxY" : 131,
    "prop" : {
      "x" : 70,
      "y" : 109,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 73,
      "y" : 109
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 115,
          "y" : 109
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 115,
          "y" : 109
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 579,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 114,
          "y" : 106
        },
        "to" : {
          "x" : 196,
          "y" : 68
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 583,
    "reactomeId" : 9668830,
    "displayName" : "CST complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 346,
      "y" : 67
    },
    "minX" : 295,
    "maxX" : 1209,
    "minY" : 25,
    "maxY" : 539,
    "prop" : {
      "x" : 295,
      "y" : 55,
      "width" : 102,
      "height" : 24
    },
    "textPosition" : {
      "x" : 303,
      "y" : 58
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 397,
          "y" : 55
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 397,
          "y" : 55
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 579,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 422,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 355,
          "y" : 82
        },
        "to" : {
          "x" : 407,
          "y" : 141
        }
      }, {
        "from" : {
          "x" : 407,
          "y" : 141
        },
        "to" : {
          "x" : 604,
          "y" : 187
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 39,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 365,
          "y" : 52
        },
        "to" : {
          "x" : 413,
          "y" : 25
        }
      }, {
        "from" : {
          "x" : 413,
          "y" : 25
        },
        "to" : {
          "x" : 939,
          "y" : 50
        }
      }, {
        "from" : {
          "x" : 939,
          "y" : 50
        },
        "to" : {
          "x" : 939,
          "y" : 191
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 935,
          "y" : 184
        },
        "b" : {
          "x" : 939,
          "y" : 191
        },
        "c" : {
          "x" : 943,
          "y" : 184
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 943,
          "y" : 184
        }
      }
    }, {
      "edgeId" : 49,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 400,
          "y" : 67
        },
        "to" : {
          "x" : 1120,
          "y" : 82
        }
      }, {
        "from" : {
          "x" : 1120,
          "y" : 82
        },
        "to" : {
          "x" : 1130,
          "y" : 539
        }
      }, {
        "from" : {
          "x" : 1130,
          "y" : 539
        },
        "to" : {
          "x" : 1209,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 407,
          "y" : 63
        },
        "b" : {
          "x" : 400,
          "y" : 67
        },
        "c" : {
          "x" : 407,
          "y" : 71
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 407,
          "y" : 71
        }
      }
    } ]
  }, {
    "id" : 73,
    "reactomeId" : 181921,
    "displayName" : "Nucleosome",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1327,
      "y" : 703
    },
    "minX" : 1277,
    "maxX" : 1477,
    "minY" : 686,
    "maxY" : 875,
    "prop" : {
      "x" : 1277,
      "y" : 692,
      "width" : 101,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1285,
      "y" : 693
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1378,
          "y" : 692
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1378,
          "y" : 692
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 78,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1336,
          "y" : 717
        },
        "to" : {
          "x" : 1477,
          "y" : 875
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 79,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1322,
          "y" : 717
        },
        "to" : {
          "x" : 1292,
          "y" : 797
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 74,
    "reactomeId" : 176703,
    "displayName" : "Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1532,
      "y" : 1004
    },
    "minX" : 1466,
    "maxX" : 1604,
    "minY" : 875,
    "maxY" : 1051,
    "prop" : {
      "x" : 1466,
      "y" : 957,
      "width" : 132,
      "height" : 94
    },
    "textPosition" : {
      "x" : 1469,
      "y" : 946
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1598,
          "y" : 957
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1598,
          "y" : 957
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 78,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1511,
          "y" : 954
        },
        "to" : {
          "x" : 1477,
          "y" : 875
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 79,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 75,
    "reactomeId" : 174890,
    "displayName" : "POT1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1269,
      "y" : 736
    },
    "minX" : 1247,
    "maxX" : 1477,
    "minY" : 719,
    "maxY" : 875,
    "prop" : {
      "x" : 1247,
      "y" : 725,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1249,
      "y" : 725
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1292,
          "y" : 725
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1292,
          "y" : 725
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 78,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1285,
          "y" : 750
        },
        "to" : {
          "x" : 1477,
          "y" : 875
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 79,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1273,
          "y" : 750
        },
        "to" : {
          "x" : 1292,
          "y" : 797
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 76,
    "reactomeId" : 174898,
    "displayName" : "Shelterin complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1474,
      "y" : 762
    },
    "minX" : 1292,
    "maxX" : 1519,
    "minY" : 738,
    "maxY" : 875,
    "prop" : {
      "x" : 1435,
      "y" : 744,
      "width" : 78,
      "height" : 36
    },
    "textPosition" : {
      "x" : 1440,
      "y" : 745
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1513,
          "y" : 744
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1513,
          "y" : 744
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 78,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1474,
          "y" : 783
        },
        "to" : {
          "x" : 1477,
          "y" : 875
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 79,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1432,
          "y" : 769
        },
        "to" : {
          "x" : 1292,
          "y" : 797
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77,
    "reactomeId" : 182751,
    "displayName" : "Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1626,
      "y" : 839
    },
    "minX" : 1560,
    "maxX" : 1736,
    "minY" : 772,
    "maxY" : 901,
    "prop" : {
      "x" : 1560,
      "y" : 778,
      "width" : 132,
      "height" : 123
    },
    "textPosition" : {
      "x" : 1563,
      "y" : 768
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1692,
          "y" : 778
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1692,
          "y" : 778
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 78,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 2490,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1695,
          "y" : 829
        },
        "to" : {
          "x" : 1736,
          "y" : 823
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 1871,
    "reactomeId" : 67387,
    "displayName" : "WRN",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1023,
      "y" : 815
    },
    "minX" : 1003,
    "maxX" : 1095,
    "minY" : 798,
    "maxY" : 917,
    "prop" : {
      "x" : 1003,
      "y" : 804,
      "width" : 41,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1005,
      "y" : 804
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1044,
          "y" : 804
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1044,
          "y" : 804
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 70,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 1030,
          "y" : 829
        },
        "to" : {
          "x" : 1095,
          "y" : 917
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1088,
          "y" : 914
        },
        "b" : {
          "x" : 1095,
          "y" : 917
        },
        "c" : {
          "x" : 1094,
          "y" : 909
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 1094,
          "y" : 909
        }
      }
    } ]
  }, {
    "id" : 3664,
    "reactomeId" : 5686112,
    "displayName" : "RTEL1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 458,
      "y" : 344
    },
    "minX" : 385,
    "maxX" : 505,
    "minY" : 277,
    "maxY" : 522,
    "prop" : {
      "x" : 432,
      "y" : 335,
      "width" : 53,
      "height" : 19
    },
    "textPosition" : {
      "x" : 436,
      "y" : 334
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 485,
          "y" : 335
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 485,
          "y" : 335
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 25,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 447,
          "y" : 332
        },
        "to" : {
          "x" : 385,
          "y" : 277
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 3803,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 460,
          "y" : 357
        },
        "to" : {
          "x" : 505,
          "y" : 522
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 466,
          "y" : 363
        },
        "b" : {
          "x" : 460,
          "y" : 357
        },
        "c" : {
          "x" : 458,
          "y" : 365
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 458,
          "y" : 365
        }
      }
    } ]
  }, {
    "id" : 81,
    "reactomeId" : 53787,
    "displayName" : "LIG1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1094,
      "y" : 754
    },
    "minX" : 1074,
    "maxX" : 1146,
    "minY" : 737,
    "maxY" : 765,
    "prop" : {
      "x" : 1074,
      "y" : 743,
      "width" : 41,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1077,
      "y" : 743
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1115,
          "y" : 743
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1115,
          "y" : 743
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 56,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1118,
          "y" : 754
        },
        "to" : {
          "x" : 1138,
          "y" : 754
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1142,
          "y" : 754
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1142,
          "y" : 754
        }
      }
    } ]
  }, {
    "id" : 3465,
    "reactomeId" : 9671097,
    "displayName" : "Telomeric G-strand chromosome end with two additional single strand repeats",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 564,
      "y" : 398
    },
    "minX" : 490,
    "maxX" : 645,
    "minY" : 187,
    "maxY" : 522,
    "prop" : {
      "x" : 490,
      "y" : 365,
      "width" : 149,
      "height" : 66
    },
    "textPosition" : {
      "x" : 490,
      "y" : 368
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 639,
          "y" : 365
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 639,
          "y" : 365
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3803,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 548,
          "y" : 434
        },
        "to" : {
          "x" : 505,
          "y" : 522
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 549,
          "y" : 442
        },
        "b" : {
          "x" : 548,
          "y" : 434
        },
        "c" : {
          "x" : 541,
          "y" : 438
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 541,
          "y" : 438
        }
      }
    }, {
      "edgeId" : 422,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 570,
          "y" : 362
        },
        "to" : {
          "x" : 604,
          "y" : 187
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 2445,
    "reactomeId" : 2559586,
    "displayName" : "DNA Damage/Telomere Stress Induced Senescence",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 1701,
      "y" : 1206
    },
    "minX" : 1631,
    "maxX" : 1771,
    "minY" : 1164,
    "maxY" : 1249,
    "prop" : {
      "x" : 1631,
      "y" : 1164,
      "width" : 140,
      "height" : 85
    },
    "textPosition" : {
      "x" : 1634,
      "y" : 1171
    },
    "connectors" : [ ]
  }, {
    "id" : 2458,
    "reactomeId" : 9670098,
    "displayName" : "Telomere:Shelterin:Nucleosome:ATRX:DAXX",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1908,
      "y" : 819
    },
    "minX" : 1856,
    "maxX" : 1967,
    "minY" : 781,
    "maxY" : 880,
    "prop" : {
      "x" : 1856,
      "y" : 787,
      "width" : 105,
      "height" : 64
    },
    "textPosition" : {
      "x" : 1864,
      "y" : 788
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1961,
          "y" : 787
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1961,
          "y" : 787
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2627,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1909,
          "y" : 854
        },
        "to" : {
          "x" : 1911,
          "y" : 880
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 2490,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 932,
    "reactomeId" : 113518,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1706,
      "y" : 548
    },
    "minX" : 1664,
    "maxX" : 1729,
    "minY" : 532,
    "maxY" : 563,
    "prop" : {
      "x" : 1684,
      "y" : 533,
      "width" : 44,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1689,
      "y" : 537
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1723,
          "y" : 538
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1723,
          "y" : 538
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 48,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1681,
          "y" : 554
        },
        "to" : {
          "x" : 1664,
          "y" : 561
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 933,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1708,
      "y" : 610
    },
    "minX" : 1664,
    "maxX" : 1731,
    "minY" : 561,
    "maxY" : 625,
    "prop" : {
      "x" : 1686,
      "y" : 595,
      "width" : 44,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1692,
      "y" : 599
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1725,
          "y" : 600
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1725,
          "y" : 600
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 48,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1694,
          "y" : 592
        },
        "to" : {
          "x" : 1664,
          "y" : 561
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 935,
    "reactomeId" : 113550,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1695,
      "y" : 357
    },
    "minX" : 1660,
    "maxX" : 1711,
    "minY" : 343,
    "maxY" : 435,
    "prop" : {
      "x" : 1680,
      "y" : 344,
      "width" : 30,
      "height" : 26
    },
    "textPosition" : {
      "x" : 1685,
      "y" : 346
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1705,
          "y" : 349
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1705,
          "y" : 349
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 48,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1689,
          "y" : 373
        },
        "to" : {
          "x" : 1660,
          "y" : 435
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1690,
          "y" : 381
        },
        "b" : {
          "x" : 1689,
          "y" : 373
        },
        "c" : {
          "x" : 1682,
          "y" : 378
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1682,
          "y" : 378
        }
      }
    } ]
  }, {
    "id" : 936,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1718,
      "y" : 420
    },
    "minX" : 1660,
    "maxX" : 1741,
    "minY" : 407,
    "maxY" : 435,
    "prop" : {
      "x" : 1696,
      "y" : 408,
      "width" : 44,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1701,
      "y" : 409
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1735,
          "y" : 413
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1735,
          "y" : 413
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 48,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1693,
          "y" : 425
        },
        "to" : {
          "x" : 1660,
          "y" : 435
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1688,
          "y" : 431
        },
        "b" : {
          "x" : 1693,
          "y" : 425
        },
        "c" : {
          "x" : 1685,
          "y" : 423
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1685,
          "y" : 423
        }
      }
    } ]
  }, {
    "id" : 1716,
    "reactomeId" : 9668968,
    "displayName" : "BLM,WRN",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 854,
      "y" : 763
    },
    "minX" : 815,
    "maxX" : 895,
    "minY" : 752,
    "maxY" : 827,
    "prop" : {
      "x" : 815,
      "y" : 752,
      "width" : 78,
      "height" : 22
    },
    "textPosition" : {
      "x" : 822,
      "y" : 752
    },
    "connectors" : [ {
      "edgeId" : 58,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 860,
          "y" : 780
        },
        "to" : {
          "x" : 889,
          "y" : 820
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 891,
          "y" : 823
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 891,
          "y" : 823
        }
      }
    } ]
  }, {
    "id" : 1720,
    "reactomeId" : 113518,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 949,
      "y" : 842
    },
    "minX" : 928,
    "maxX" : 971,
    "minY" : 810,
    "maxY" : 853,
    "prop" : {
      "x" : 928,
      "y" : 831,
      "width" : 42,
      "height" : 22
    },
    "textPosition" : {
      "x" : 932,
      "y" : 831
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 965,
          "y" : 836
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 965,
          "y" : 836
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 58,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 956,
          "y" : 828
        },
        "to" : {
          "x" : 971,
          "y" : 810
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 1721,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1008,
      "y" : 846
    },
    "minX" : 971,
    "maxX" : 1027,
    "minY" : 810,
    "maxY" : 855,
    "prop" : {
      "x" : 990,
      "y" : 837,
      "width" : 36,
      "height" : 18
    },
    "textPosition" : {
      "x" : 992,
      "y" : 836
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1021,
          "y" : 842
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1021,
          "y" : 842
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 58,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 998,
          "y" : 834
        },
        "to" : {
          "x" : 971,
          "y" : 810
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 456,
    "reactomeId" : 9668602,
    "displayName" : "POLA:primase:G-strand extended telomere end",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 787,
      "y" : 201
    },
    "minX" : 730,
    "maxX" : 934,
    "minY" : 151,
    "maxY" : 233,
    "prop" : {
      "x" : 730,
      "y" : 169,
      "width" : 115,
      "height" : 64
    },
    "textPosition" : {
      "x" : 730,
      "y" : 184
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 845,
          "y" : 169
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 845,
          "y" : 169
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 422,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 39,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 848,
          "y" : 199
        },
        "to" : {
          "x" : 899,
          "y" : 199
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 39,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 848,
          "y" : 171
        },
        "to" : {
          "x" : 884,
          "y" : 151
        }
      }, {
        "from" : {
          "x" : 884,
          "y" : 151
        },
        "to" : {
          "x" : 927,
          "y" : 189
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 930,
          "y" : 192
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 930,
          "y" : 192
        }
      }
    } ]
  }, {
    "id" : 202,
    "reactomeId" : 6790665,
    "displayName" : "NOP10",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 174,
      "y" : 468
    },
    "minX" : 147,
    "maxX" : 249,
    "minY" : 449,
    "maxY" : 479,
    "prop" : {
      "x" : 147,
      "y" : 457,
      "width" : 55,
      "height" : 22
    },
    "textPosition" : {
      "x" : 149,
      "y" : 457
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 202,
          "y" : 457
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 202,
          "y" : 457
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 205,
          "y" : 461
        },
        "to" : {
          "x" : 249,
          "y" : 449
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 221,
            "y" : 449
          },
          "b" : {
            "x" : 233,
            "y" : 461
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 227,
            "y" : 455
          }
        }
      }
    } ]
  }, {
    "id" : 203,
    "reactomeId" : 6790707,
    "displayName" : "GAR1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 201,
      "y" : 561
    },
    "minX" : 179,
    "maxX" : 249,
    "minY" : 449,
    "maxY" : 572,
    "prop" : {
      "x" : 179,
      "y" : 550,
      "width" : 45,
      "height" : 22
    },
    "textPosition" : {
      "x" : 181,
      "y" : 550
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 224,
          "y" : 550
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 224,
          "y" : 550
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 26,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 205,
          "y" : 547
        },
        "to" : {
          "x" : 249,
          "y" : 449
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 221,
            "y" : 492
          },
          "b" : {
            "x" : 233,
            "y" : 504
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 227,
            "y" : 498
          }
        }
      }
    } ]
  }, {
    "id" : 2773,
    "reactomeId" : 9670147,
    "displayName" : "Telomeric DNA",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 1828,
      "y" : 1115
    },
    "minX" : 1771,
    "maxX" : 1886,
    "minY" : 1104,
    "maxY" : 1126,
    "prop" : {
      "x" : 1771,
      "y" : 1104,
      "width" : 115,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1779,
      "y" : 1104
    },
    "connectors" : [ {
      "edgeId" : 2772,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3286,
    "reactomeId" : 9671076,
    "displayName" : "Telomeric G-strand chromosome end:Shelterin",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 367,
      "y" : 211
    },
    "minX" : 263,
    "maxX" : 436,
    "minY" : 181,
    "maxY" : 277,
    "prop" : {
      "x" : 305,
      "y" : 187,
      "width" : 125,
      "height" : 49
    },
    "textPosition" : {
      "x" : 307,
      "y" : 173
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 430,
          "y" : 187
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 430,
          "y" : 187
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 25,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 373,
          "y" : 239
        },
        "to" : {
          "x" : 385,
          "y" : 277
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 3866,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 302,
          "y" : 230
        },
        "to" : {
          "x" : 263,
          "y" : 244
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 297,
          "y" : 236
        },
        "b" : {
          "x" : 302,
          "y" : 230
        },
        "c" : {
          "x" : 294,
          "y" : 229
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 294,
          "y" : 229
        }
      }
    }, {
      "edgeId" : 3813,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 302,
          "y" : 200
        },
        "to" : {
          "x" : 274,
          "y" : 196
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 2774,
    "reactomeId" : 9670084,
    "displayName" : "TERRA",
    "schemaClass" : "GenomeEncodedEntity",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 2038,
      "y" : 1120
    },
    "minX" : 2011,
    "maxX" : 2066,
    "minY" : 1109,
    "maxY" : 1131,
    "prop" : {
      "x" : 2011,
      "y" : 1109,
      "width" : 55,
      "height" : 22
    },
    "textPosition" : {
      "x" : 2015,
      "y" : 1109
    },
    "connectors" : [ {
      "edgeId" : 2772,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 2775,
    "reactomeId" : 209680,
    "displayName" : "RNA Polymerase II holoenzyme complex (generic)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1927,
      "y" : 1214
    },
    "minX" : 1861,
    "maxX" : 2000,
    "minY" : 1127,
    "maxY" : 1246,
    "prop" : {
      "x" : 1861,
      "y" : 1182,
      "width" : 133,
      "height" : 64
    },
    "textPosition" : {
      "x" : 1866,
      "y" : 1197
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1994,
          "y" : 1182
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1994,
          "y" : 1182
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 2772,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1925,
          "y" : 1179
        },
        "to" : {
          "x" : 1924,
          "y" : 1135
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1924,
          "y" : 1131
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1924,
          "y" : 1131
        }
      }
    } ]
  }, {
    "id" : 1755,
    "reactomeId" : 9668967,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 863,
      "y" : 951
    },
    "minX" : 846,
    "maxX" : 882,
    "minY" : 850,
    "maxY" : 966,
    "prop" : {
      "x" : 846,
      "y" : 936,
      "width" : 35,
      "height" : 30
    },
    "textPosition" : {
      "x" : 850,
      "y" : 940
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 876,
          "y" : 941
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 876,
          "y" : 941
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 58,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 861,
          "y" : 933
        },
        "to" : {
          "x" : 855,
          "y" : 850
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 857,
          "y" : 926
        },
        "b" : {
          "x" : 861,
          "y" : 933
        },
        "c" : {
          "x" : 864,
          "y" : 926
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 864,
          "y" : 926
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 3804,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 768,
      "y" : 775
    },
    "minX" : 737,
    "maxX" : 791,
    "minY" : 742,
    "maxY" : 789,
    "prop" : {
      "x" : 747,
      "y" : 762,
      "width" : 43,
      "height" : 27
    },
    "textPosition" : {
      "x" : 753,
      "y" : 765
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 785,
          "y" : 767
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 785,
          "y" : 767
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3803,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 755,
          "y" : 759
        },
        "to" : {
          "x" : 737,
          "y" : 742
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 1757,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 808,
      "y" : 948
    },
    "minX" : 789,
    "maxX" : 855,
    "minY" : 850,
    "maxY" : 960,
    "prop" : {
      "x" : 789,
      "y" : 937,
      "width" : 39,
      "height" : 23
    },
    "textPosition" : {
      "x" : 792,
      "y" : 938
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 823,
          "y" : 942
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 823,
          "y" : 942
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 58,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 813,
          "y" : 934
        },
        "to" : {
          "x" : 855,
          "y" : 850
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 813,
          "y" : 926
        },
        "b" : {
          "x" : 813,
          "y" : 934
        },
        "c" : {
          "x" : 820,
          "y" : 930
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 820,
          "y" : 930
        }
      }
    } ]
  }, {
    "id" : 3806,
    "reactomeId" : 113518,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 706,
      "y" : 776
    },
    "minX" : 686,
    "maxX" : 737,
    "minY" : 742,
    "maxY" : 789,
    "prop" : {
      "x" : 686,
      "y" : 763,
      "width" : 41,
      "height" : 26
    },
    "textPosition" : {
      "x" : 689,
      "y" : 765
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 722,
          "y" : 768
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 722,
          "y" : 768
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3803,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 717,
          "y" : 760
        },
        "to" : {
          "x" : 737,
          "y" : 742
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 3807,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 409,
      "y" : 580
    },
    "minX" : 389,
    "maxX" : 505,
    "minY" : 522,
    "maxY" : 593,
    "prop" : {
      "x" : 389,
      "y" : 567,
      "width" : 41,
      "height" : 26
    },
    "textPosition" : {
      "x" : 393,
      "y" : 569
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 425,
          "y" : 572
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 425,
          "y" : 572
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3803,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 433,
          "y" : 567
        },
        "to" : {
          "x" : 505,
          "y" : 522
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 437,
          "y" : 560
        },
        "b" : {
          "x" : 433,
          "y" : 567
        },
        "c" : {
          "x" : 441,
          "y" : 567
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 441,
          "y" : 567
        }
      }
    } ]
  }, {
    "id" : 3808,
    "reactomeId" : 418319,
    "displayName" : "PIF1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 585,
      "y" : 816
    },
    "minX" : 567,
    "maxX" : 610,
    "minY" : 758,
    "maxY" : 827,
    "prop" : {
      "x" : 567,
      "y" : 805,
      "width" : 37,
      "height" : 22
    },
    "textPosition" : {
      "x" : 568,
      "y" : 805
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 604,
          "y" : 805
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 604,
          "y" : 805
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3803,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 585,
          "y" : 802
        },
        "to" : {
          "x" : 586,
          "y" : 766
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 586,
          "y" : 762
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 586,
          "y" : 762
        }
      }
    } ]
  }, {
    "id" : 3810,
    "reactomeId" : 113550,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 433,
      "y" : 626
    },
    "minX" : 416,
    "maxX" : 505,
    "minY" : 522,
    "maxY" : 639,
    "prop" : {
      "x" : 416,
      "y" : 614,
      "width" : 35,
      "height" : 25
    },
    "textPosition" : {
      "x" : 424,
      "y" : 616
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 446,
          "y" : 619
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 446,
          "y" : 619
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3803,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 441,
          "y" : 611
        },
        "to" : {
          "x" : 505,
          "y" : 522
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 442,
          "y" : 603
        },
        "b" : {
          "x" : 441,
          "y" : 611
        },
        "c" : {
          "x" : 448,
          "y" : 608
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 448,
          "y" : 608
        }
      }
    } ]
  }, {
    "id" : 3812,
    "reactomeId" : 9668967,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 473,
      "y" : 667
    },
    "minX" : 456,
    "maxX" : 505,
    "minY" : 522,
    "maxY" : 681,
    "prop" : {
      "x" : 456,
      "y" : 653,
      "width" : 34,
      "height" : 28
    },
    "textPosition" : {
      "x" : 459,
      "y" : 656
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 485,
          "y" : 658
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 485,
          "y" : 658
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3803,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 476,
          "y" : 650
        },
        "to" : {
          "x" : 505,
          "y" : 522
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 474,
          "y" : 642
        },
        "b" : {
          "x" : 476,
          "y" : 650
        },
        "c" : {
          "x" : 481,
          "y" : 644
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 481,
          "y" : 644
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 3814,
    "reactomeId" : 29358,
    "displayName" : "ATP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 292,
      "y" : 152
    },
    "minX" : 272,
    "maxX" : 314,
    "minY" : 141,
    "maxY" : 196,
    "prop" : {
      "x" : 272,
      "y" : 142,
      "width" : 41,
      "height" : 21
    },
    "textPosition" : {
      "x" : 277,
      "y" : 142
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 308,
          "y" : 147
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 308,
          "y" : 147
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3813,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 287,
          "y" : 166
        },
        "to" : {
          "x" : 274,
          "y" : 196
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 3815,
    "reactomeId" : 9686523,
    "displayName" : "Telomeric G-strand chromosome end:Shelterin (p-S365-TERF2)",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 99,
      "y" : 191
    },
    "minX" : 19,
    "maxX" : 225,
    "minY" : 159,
    "maxY" : 245,
    "prop" : {
      "x" : 19,
      "y" : 165,
      "width" : 161,
      "height" : 53
    },
    "textPosition" : {
      "x" : 34,
      "y" : 155
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 180,
          "y" : 165
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 180,
          "y" : 165
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3866,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 132,
          "y" : 221
        },
        "to" : {
          "x" : 167,
          "y" : 245
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 3813,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 183,
          "y" : 192
        },
        "to" : {
          "x" : 225,
          "y" : 194
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 190,
          "y" : 188
        },
        "b" : {
          "x" : 183,
          "y" : 192
        },
        "c" : {
          "x" : 190,
          "y" : 196
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 190,
          "y" : 196
        }
      }
    } ]
  }, {
    "id" : 1768,
    "reactomeId" : 113550,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 778,
      "y" : 912
    },
    "minX" : 764,
    "maxX" : 855,
    "minY" : 850,
    "maxY" : 923,
    "prop" : {
      "x" : 764,
      "y" : 901,
      "width" : 29,
      "height" : 22
    },
    "textPosition" : {
      "x" : 769,
      "y" : 901
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 788,
          "y" : 906
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 788,
          "y" : 906
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 58,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 791,
          "y" : 898
        },
        "to" : {
          "x" : 855,
          "y" : 850
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 794,
          "y" : 891
        },
        "b" : {
          "x" : 791,
          "y" : 898
        },
        "c" : {
          "x" : 799,
          "y" : 897
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 799,
          "y" : 897
        }
      }
    } ]
  }, {
    "id" : 3816,
    "reactomeId" : 113582,
    "displayName" : "ADP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 207,
      "y" : 154
    },
    "minX" : 189,
    "maxX" : 226,
    "minY" : 142,
    "maxY" : 194,
    "prop" : {
      "x" : 189,
      "y" : 143,
      "width" : 36,
      "height" : 22
    },
    "textPosition" : {
      "x" : 190,
      "y" : 143
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 220,
          "y" : 148
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 220,
          "y" : 148
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 3813,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 211,
          "y" : 168
        },
        "to" : {
          "x" : 225,
          "y" : 194
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 218,
          "y" : 172
        },
        "b" : {
          "x" : 211,
          "y" : 168
        },
        "c" : {
          "x" : 211,
          "y" : 176
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 211,
          "y" : 176
        }
      }
    } ]
  }, {
    "id" : 3817,
    "reactomeId" : 187952,
    "displayName" : "CCNA:p-T160-CDK2",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 244,
      "y" : 114
    },
    "minX" : 178,
    "maxX" : 468,
    "minY" : 97,
    "maxY" : 271,
    "prop" : {
      "x" : 178,
      "y" : 103,
      "width" : 133,
      "height" : 23
    },
    "textPosition" : {
      "x" : 182,
      "y" : 105
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 311,
          "y" : 103
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 311,
          "y" : 103
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 25,
      "type" : "INHIBITOR",
      "segments" : [ {
        "from" : {
          "x" : 286,
          "y" : 129
        },
        "to" : {
          "x" : 468,
          "y" : 174
        }
      }, {
        "from" : {
          "x" : 468,
          "y" : 174
        },
        "to" : {
          "x" : 420,
          "y" : 269
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 416,
          "y" : 267
        },
        "b" : {
          "x" : 424,
          "y" : 271
        },
        "c" : {
          "x" : 420,
          "y" : 269
        },
        "type" : "STOP",
        "centre" : {
          "x" : 420,
          "y" : 269
        }
      }
    }, {
      "edgeId" : 3813,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 244,
          "y" : 129
        },
        "to" : {
          "x" : 246,
          "y" : 182
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 246,
          "y" : 186
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 246,
          "y" : 186
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 579,
    "reactomeId" : 9668831,
    "displayName" : "CST complex formation",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 249,
      "y" : 73
    },
    "minX" : 196,
    "maxX" : 292,
    "minY" : 68,
    "maxY" : 78,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 196,
        "y" : 68
      },
      "to" : {
        "x" : 249,
        "y" : 73
      }
    }, {
      "from" : {
        "x" : 249,
        "y" : 73
      },
      "to" : {
        "x" : 292,
        "y" : 70
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 285,
        "y" : 74
      },
      "b" : {
        "x" : 292,
        "y" : 70
      },
      "c" : {
        "x" : 285,
        "y" : 66
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 285,
        "y" : 66
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 249,
        "y" : 73
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 249,
        "y" : 73
      }
    },
    "inputs" : [ {
      "id" : 580,
      "points" : [ {
        "x" : 119,
        "y" : 76
      } ]
    }, {
      "id" : 581,
      "points" : [ {
        "x" : 160,
        "y" : 51
      } ]
    }, {
      "id" : 582,
      "points" : [ {
        "x" : 114,
        "y" : 106
      } ]
    } ],
    "outputs" : [ {
      "id" : 583
    } ]
  }, {
    "id" : 2627,
    "reactomeId" : 9670114,
    "displayName" : "Histone H3.3 deposition at telomere",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1913,
      "y" : 908
    },
    "minX" : 1907,
    "maxX" : 1919,
    "minY" : 880,
    "maxY" : 941,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1911,
        "y" : 880
      },
      "to" : {
        "x" : 1913,
        "y" : 908
      }
    }, {
      "from" : {
        "x" : 1913,
        "y" : 908
      },
      "to" : {
        "x" : 1916,
        "y" : 941
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1907,
        "y" : 902
      },
      "b" : {
        "x" : 1919,
        "y" : 914
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1913,
        "y" : 908
      }
    },
    "inputs" : [ {
      "id" : 2458,
      "points" : [ {
        "x" : 1909,
        "y" : 854
      } ]
    }, {
      "id" : 2614,
      "points" : [ {
        "x" : 1874,
        "y" : 878
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 2615,
      "points" : [ {
        "x" : 1919,
        "y" : 977
      } ]
    }, {
      "id" : 2616,
      "points" : [ {
        "x" : 1869,
        "y" : 946
      } ],
      "stoichiometry" : 2
    } ],
    "activators" : [ {
      "id" : 2368,
      "points" : [ {
        "x" : 1799,
        "y" : 730
      }, {
        "x" : 2010,
        "y" : 733
      }, {
        "x" : 2017,
        "y" : 906
      } ]
    } ]
  }, {
    "id" : 69,
    "reactomeId" : 174441,
    "displayName" : "Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1141,
      "y" : 991
    },
    "minX" : 1135,
    "maxX" : 1149,
    "minY" : 961,
    "maxY" : 1034,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1135,
        "y" : 1034
      },
      "to" : {
        "x" : 1141,
        "y" : 991
      }
    }, {
      "from" : {
        "x" : 1141,
        "y" : 991
      },
      "to" : {
        "x" : 1149,
        "y" : 961
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1135,
        "y" : 985
      },
      "b" : {
        "x" : 1147,
        "y" : 997
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1141,
        "y" : 991
      }
    },
    "inputs" : [ {
      "id" : 61
    } ],
    "outputs" : [ {
      "id" : 65,
      "points" : [ {
        "x" : 1053,
        "y" : 935
      } ]
    }, {
      "id" : 59,
      "points" : [ {
        "x" : 1308,
        "y" : 945
      } ]
    }, {
      "id" : 60,
      "points" : [ {
        "x" : 1358,
        "y" : 997
      } ]
    }, {
      "id" : 66,
      "points" : [ {
        "x" : 1264,
        "y" : 1041
      } ]
    }, {
      "id" : 67,
      "points" : [ {
        "x" : 986,
        "y" : 1235
      }, {
        "x" : 1219,
        "y" : 1162
      }, {
        "x" : 1211,
        "y" : 1020
      } ]
    }, {
      "id" : 64,
      "points" : [ {
        "x" : 1357,
        "y" : 1049
      } ]
    }, {
      "id" : 63,
      "points" : [ {
        "x" : 1055,
        "y" : 971
      } ]
    } ],
    "catalysts" : [ {
      "id" : 61,
      "points" : [ {
        "x" : 1159,
        "y" : 1034
      }, {
        "x" : 1178,
        "y" : 1012
      } ]
    } ]
  }, {
    "id" : 70,
    "reactomeId" : 174446,
    "displayName" : "Removal of remaining Flap from the C-strand",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1100,
      "y" : 924
    },
    "minX" : 1053,
    "maxX" : 1137,
    "minY" : 881,
    "maxY" : 930,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1053,
        "y" : 921
      },
      "to" : {
        "x" : 1100,
        "y" : 924
      }
    }, {
      "from" : {
        "x" : 1100,
        "y" : 924
      },
      "to" : {
        "x" : 1137,
        "y" : 881
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1136,
        "y" : 889
      },
      "b" : {
        "x" : 1137,
        "y" : 881
      },
      "c" : {
        "x" : 1129,
        "y" : 884
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1129,
        "y" : 884
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1094,
        "y" : 918
      },
      "b" : {
        "x" : 1106,
        "y" : 930
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1100,
        "y" : 924
      }
    },
    "inputs" : [ {
      "id" : 65
    } ],
    "outputs" : [ {
      "id" : 54
    } ],
    "catalysts" : [ {
      "id" : 68,
      "points" : [ {
        "x" : 1194,
        "y" : 927
      } ]
    } ],
    "activators" : [ {
      "id" : 1871,
      "points" : [ {
        "x" : 1030,
        "y" : 829
      } ]
    } ]
  }, {
    "id" : 71,
    "reactomeId" : 174445,
    "displayName" : "RPA binds to the Flap on the C-strand",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 718,
      "y" : 1075
    },
    "minX" : 713,
    "maxX" : 885,
    "minY" : 981,
    "maxY" : 1080,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 718,
        "y" : 981
      },
      "to" : {
        "x" : 718,
        "y" : 1075
      }
    }, {
      "from" : {
        "x" : 718,
        "y" : 1075
      },
      "to" : {
        "x" : 885,
        "y" : 1075
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 878,
        "y" : 1079
      },
      "b" : {
        "x" : 885,
        "y" : 1075
      },
      "c" : {
        "x" : 878,
        "y" : 1071
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 878,
        "y" : 1071
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 718,
        "y" : 1075
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 718,
        "y" : 1075
      }
    },
    "inputs" : [ {
      "id" : 52,
      "points" : [ {
        "x" : 710,
        "y" : 892
      } ]
    }, {
      "id" : 63,
      "points" : [ {
        "x" : 921,
        "y" : 979
      } ]
    } ],
    "outputs" : [ {
      "id" : 62
    } ]
  }, {
    "id" : 72,
    "reactomeId" : 174451,
    "displayName" : "Recruitment of DNA2 endonuclease to the C strand",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1032,
      "y" : 1149
    },
    "minX" : 958,
    "maxX" : 1074,
    "minY" : 1121,
    "maxY" : 1165,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 958,
        "y" : 1165
      },
      "to" : {
        "x" : 1032,
        "y" : 1149
      }
    }, {
      "from" : {
        "x" : 1032,
        "y" : 1149
      },
      "to" : {
        "x" : 1074,
        "y" : 1121
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1070,
        "y" : 1128
      },
      "b" : {
        "x" : 1074,
        "y" : 1121
      },
      "c" : {
        "x" : 1066,
        "y" : 1122
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1066,
        "y" : 1122
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1032,
        "y" : 1149
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1032,
        "y" : 1149
      }
    },
    "inputs" : [ {
      "id" : 67,
      "points" : [ {
        "x" : 959,
        "y" : 1228
      } ]
    }, {
      "id" : 62,
      "points" : [ {
        "x" : 955,
        "y" : 1120
      } ]
    } ],
    "outputs" : [ {
      "id" : 61
    } ]
  }, {
    "id" : 78,
    "reactomeId" : 176700,
    "displayName" : "Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1513,
      "y" : 863
    },
    "minX" : 1477,
    "maxX" : 1557,
    "minY" : 853,
    "maxY" : 875,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1477,
        "y" : 875
      },
      "to" : {
        "x" : 1513,
        "y" : 863
      }
    }, {
      "from" : {
        "x" : 1513,
        "y" : 863
      },
      "to" : {
        "x" : 1557,
        "y" : 853
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1551,
        "y" : 858
      },
      "b" : {
        "x" : 1557,
        "y" : 853
      },
      "c" : {
        "x" : 1549,
        "y" : 851
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1549,
        "y" : 851
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1507,
        "y" : 857
      },
      "b" : {
        "x" : 1519,
        "y" : 869
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1513,
        "y" : 863
      }
    },
    "inputs" : [ {
      "id" : 73,
      "points" : [ {
        "x" : 1336,
        "y" : 717
      } ]
    }, {
      "id" : 74,
      "points" : [ {
        "x" : 1511,
        "y" : 954
      } ]
    }, {
      "id" : 76,
      "points" : [ {
        "x" : 1474,
        "y" : 783
      } ]
    }, {
      "id" : 75,
      "points" : [ {
        "x" : 1285,
        "y" : 750
      } ]
    } ],
    "outputs" : [ {
      "id" : 77
    } ]
  }, {
    "id" : 79,
    "reactomeId" : 181450,
    "displayName" : "Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1311,
      "y" : 845
    },
    "minX" : 1292,
    "maxX" : 1466,
    "minY" : 797,
    "maxY" : 954,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1292,
        "y" : 797
      },
      "to" : {
        "x" : 1311,
        "y" : 845
      }
    }, {
      "from" : {
        "x" : 1311,
        "y" : 845
      },
      "to" : {
        "x" : 1466,
        "y" : 954
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1458,
        "y" : 953
      },
      "b" : {
        "x" : 1466,
        "y" : 954
      },
      "c" : {
        "x" : 1463,
        "y" : 947
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1463,
        "y" : 947
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1311,
        "y" : 845
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1311,
        "y" : 845
      }
    },
    "inputs" : [ {
      "id" : 75,
      "points" : [ {
        "x" : 1273,
        "y" : 750
      } ]
    }, {
      "id" : 76,
      "points" : [ {
        "x" : 1432,
        "y" : 769
      } ]
    }, {
      "id" : 73,
      "points" : [ {
        "x" : 1322,
        "y" : 717
      } ]
    }, {
      "id" : 3871,
      "points" : [ {
        "x" : 1438,
        "y" : 717
      } ]
    } ],
    "outputs" : [ {
      "id" : 74
    } ]
  }, {
    "id" : 2772,
    "reactomeId" : 9670149,
    "displayName" : "TERRA transcription",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1924,
      "y" : 1119
    },
    "minX" : 1889,
    "maxX" : 2008,
    "minY" : 1113,
    "maxY" : 1125,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1889,
        "y" : 1117
      },
      "to" : {
        "x" : 1924,
        "y" : 1119
      }
    }, {
      "from" : {
        "x" : 1924,
        "y" : 1119
      },
      "to" : {
        "x" : 2008,
        "y" : 1119
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2001,
        "y" : 1123
      },
      "b" : {
        "x" : 2008,
        "y" : 1119
      },
      "c" : {
        "x" : 2001,
        "y" : 1115
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2001,
        "y" : 1115
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1918,
        "y" : 1113
      },
      "b" : {
        "x" : 1930,
        "y" : 1125
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1924,
        "y" : 1119
      }
    },
    "inputs" : [ {
      "id" : 2773
    } ],
    "outputs" : [ {
      "id" : 2774
    } ],
    "catalysts" : [ {
      "id" : 2775,
      "points" : [ {
        "x" : 1925,
        "y" : 1179
      } ]
    } ],
    "inhibitors" : [ {
      "id" : 2615,
      "points" : [ {
        "x" : 1922,
        "y" : 1061
      } ]
    } ]
  }, {
    "id" : 21,
    "reactomeId" : 163090,
    "displayName" : "Elongation Of The Telomeric Chromosome End",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 704,
      "y" : 393
    },
    "minX" : 695,
    "maxX" : 710,
    "minY" : 350,
    "maxY" : 462,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 705,
        "y" : 350
      },
      "to" : {
        "x" : 704,
        "y" : 393
      }
    }, {
      "from" : {
        "x" : 704,
        "y" : 393
      },
      "to" : {
        "x" : 695,
        "y" : 462
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 692,
        "y" : 455
      },
      "b" : {
        "x" : 695,
        "y" : 462
      },
      "c" : {
        "x" : 700,
        "y" : 456
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 700,
        "y" : 456
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 698,
        "y" : 387
      },
      "b" : {
        "x" : 710,
        "y" : 399
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 704,
        "y" : 393
      }
    },
    "inputs" : [ {
      "id" : 2,
      "points" : [ {
        "x" : 821,
        "y" : 305
      }, {
        "x" : 773,
        "y" : 336
      } ]
    }, {
      "id" : 16,
      "points" : [ {
        "x" : 707,
        "y" : 330
      } ]
    }, {
      "id" : 8,
      "points" : [ {
        "x" : 787,
        "y" : 340
      } ]
    }, {
      "id" : 18,
      "points" : [ {
        "x" : 746,
        "y" : 393
      } ]
    }, {
      "id" : 10,
      "points" : [ {
        "x" : 763,
        "y" : 366
      } ]
    } ],
    "outputs" : [ {
      "id" : 15
    } ],
    "catalysts" : [ {
      "id" : 16,
      "points" : [ {
        "x" : 685,
        "y" : 330
      }, {
        "x" : 663,
        "y" : 360
      } ]
    } ]
  }, {
    "id" : 23,
    "reactomeId" : 164617,
    "displayName" : "Elongation of Extended Telomeric Chromosome End",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 854,
      "y" : 561
    },
    "minX" : 843,
    "maxX" : 863,
    "minY" : 521,
    "maxY" : 595,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 843,
        "y" : 521
      },
      "to" : {
        "x" : 854,
        "y" : 561
      }
    }, {
      "from" : {
        "x" : 854,
        "y" : 561
      },
      "to" : {
        "x" : 863,
        "y" : 595
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 857,
        "y" : 589
      },
      "b" : {
        "x" : 863,
        "y" : 595
      },
      "c" : {
        "x" : 865,
        "y" : 587
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 865,
        "y" : 587
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 848,
        "y" : 555
      },
      "b" : {
        "x" : 860,
        "y" : 567
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 854,
        "y" : 561
      }
    },
    "inputs" : [ {
      "id" : 11,
      "points" : [ {
        "x" : 730,
        "y" : 613
      } ]
    }, {
      "id" : 8,
      "points" : [ {
        "x" : 816,
        "y" : 354
      } ]
    }, {
      "id" : 2,
      "points" : [ {
        "x" : 840,
        "y" : 305
      } ]
    }, {
      "id" : 18,
      "points" : [ {
        "x" : 771,
        "y" : 429
      } ]
    }, {
      "id" : 10,
      "points" : [ {
        "x" : 793,
        "y" : 390
      } ]
    } ],
    "outputs" : [ {
      "id" : 17
    } ],
    "catalysts" : [ {
      "id" : 11,
      "points" : [ {
        "x" : 754,
        "y" : 613
      } ]
    } ]
  }, {
    "id" : 1559,
    "reactomeId" : 9668904,
    "displayName" : "Formation of the CTF18 complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1314,
      "y" : 172
    },
    "minX" : 1280,
    "maxX" : 1338,
    "minY" : 163,
    "maxY" : 177,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1280,
        "y" : 163
      },
      "to" : {
        "x" : 1314,
        "y" : 172
      }
    }, {
      "from" : {
        "x" : 1314,
        "y" : 172
      },
      "to" : {
        "x" : 1338,
        "y" : 172
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1331,
        "y" : 176
      },
      "b" : {
        "x" : 1338,
        "y" : 172
      },
      "c" : {
        "x" : 1331,
        "y" : 168
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1331,
        "y" : 168
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1314,
        "y" : 172
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1314,
        "y" : 172
      }
    },
    "inputs" : [ {
      "id" : 1560,
      "points" : [ {
        "x" : 1231,
        "y" : 165
      } ]
    }, {
      "id" : 1561,
      "points" : [ {
        "x" : 1235,
        "y" : 139
      } ]
    }, {
      "id" : 1562,
      "points" : [ {
        "x" : 1290,
        "y" : 128
      } ]
    } ],
    "outputs" : [ {
      "id" : 1563
    } ]
  }, {
    "id" : 24,
    "reactomeId" : 164620,
    "displayName" : "Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 685,
      "y" : 570
    },
    "minX" : 679,
    "maxX" : 691,
    "minY" : 535,
    "maxY" : 613,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 688,
        "y" : 535
      },
      "to" : {
        "x" : 685,
        "y" : 570
      }
    }, {
      "from" : {
        "x" : 685,
        "y" : 570
      },
      "to" : {
        "x" : 683,
        "y" : 613
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 679,
        "y" : 606
      },
      "b" : {
        "x" : 683,
        "y" : 613
      },
      "c" : {
        "x" : 687,
        "y" : 606
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 687,
        "y" : 606
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 679,
        "y" : 564
      },
      "b" : {
        "x" : 691,
        "y" : 576
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 685,
        "y" : 570
      }
    },
    "inputs" : [ {
      "id" : 15
    } ],
    "outputs" : [ {
      "id" : 11
    } ]
  }, {
    "id" : 25,
    "reactomeId" : 163096,
    "displayName" : "Recruitment of Telomerase RNP to the Telomeric Chromosome End",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 416,
      "y" : 277
    },
    "minX" : 385,
    "maxX" : 454,
    "minY" : 272,
    "maxY" : 282,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 385,
        "y" : 277
      },
      "to" : {
        "x" : 416,
        "y" : 277
      }
    }, {
      "from" : {
        "x" : 416,
        "y" : 277
      },
      "to" : {
        "x" : 454,
        "y" : 278
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 447,
        "y" : 282
      },
      "b" : {
        "x" : 454,
        "y" : 278
      },
      "c" : {
        "x" : 447,
        "y" : 274
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 447,
        "y" : 274
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 416,
        "y" : 277
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 416,
        "y" : 277
      }
    },
    "inputs" : [ {
      "id" : 3286,
      "points" : [ {
        "x" : 373,
        "y" : 239
      } ]
    }, {
      "id" : 20,
      "points" : [ {
        "x" : 364,
        "y" : 313
      } ]
    }, {
      "id" : 3664,
      "points" : [ {
        "x" : 447,
        "y" : 332
      } ]
    } ],
    "outputs" : [ {
      "id" : 9
    } ],
    "inhibitors" : [ {
      "id" : 3817,
      "points" : [ {
        "x" : 286,
        "y" : 129
      }, {
        "x" : 468,
        "y" : 174
      } ]
    } ],
    "activators" : [ {
      "id" : 3868,
      "points" : [ {
        "x" : 252,
        "y" : 313
      }, {
        "x" : 393,
        "y" : 249
      } ]
    } ]
  }, {
    "id" : 26,
    "reactomeId" : 164616,
    "displayName" : "Biogenesis and assembly of the telomerase RNP",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 303,
      "y" : 398
    },
    "minX" : 249,
    "maxX" : 350,
    "minY" : 341,
    "maxY" : 449,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 249,
        "y" : 449
      },
      "to" : {
        "x" : 303,
        "y" : 398
      }
    }, {
      "from" : {
        "x" : 303,
        "y" : 398
      },
      "to" : {
        "x" : 350,
        "y" : 341
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 349,
        "y" : 349
      },
      "b" : {
        "x" : 350,
        "y" : 341
      },
      "c" : {
        "x" : 343,
        "y" : 344
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 343,
        "y" : 344
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 303,
        "y" : 398
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 303,
        "y" : 398
      }
    },
    "inputs" : [ {
      "id" : 203,
      "points" : [ {
        "x" : 205,
        "y" : 547
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 3,
      "points" : [ {
        "x" : 115,
        "y" : 430
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 12,
      "points" : [ {
        "x" : 195,
        "y" : 501
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 202,
      "points" : [ {
        "x" : 205,
        "y" : 461
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 7,
      "points" : [ {
        "x" : 225,
        "y" : 391
      } ]
    }, {
      "id" : 6,
      "points" : [ {
        "x" : 119,
        "y" : 394
      } ]
    }, {
      "id" : 4,
      "points" : [ {
        "x" : 233,
        "y" : 590
      } ]
    } ],
    "outputs" : [ {
      "id" : 20
    } ],
    "activators" : [ {
      "id" : 13,
      "points" : [ {
        "x" : 366,
        "y" : 486
      } ]
    }, {
      "id" : 14,
      "points" : [ {
        "x" : 303,
        "y" : 519
      } ]
    } ]
  }, {
    "id" : 3866,
    "reactomeId" : 9686524,
    "displayName" : "PP6-PPP6R3 dephosphorylates TERF2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 226,
      "y" : 245
    },
    "minX" : 167,
    "maxX" : 263,
    "minY" : 239,
    "maxY" : 251,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 167,
        "y" : 245
      },
      "to" : {
        "x" : 226,
        "y" : 245
      }
    }, {
      "from" : {
        "x" : 226,
        "y" : 245
      },
      "to" : {
        "x" : 263,
        "y" : 244
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 220,
        "y" : 239
      },
      "b" : {
        "x" : 232,
        "y" : 251
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 226,
        "y" : 245
      }
    },
    "inputs" : [ {
      "id" : 3815,
      "points" : [ {
        "x" : 132,
        "y" : 221
      } ]
    }, {
      "id" : 3867,
      "points" : [ {
        "x" : 145,
        "y" : 260
      } ]
    } ],
    "outputs" : [ {
      "id" : 3286,
      "points" : [ {
        "x" : 302,
        "y" : 230
      } ]
    }, {
      "id" : 3870,
      "points" : [ {
        "x" : 269,
        "y" : 268
      } ]
    } ],
    "catalysts" : [ {
      "id" : 3868,
      "points" : [ {
        "x" : 229,
        "y" : 313
      } ]
    } ]
  }, {
    "id" : 27,
    "reactomeId" : 163099,
    "displayName" : "Alignment Of The RNA Template On The Telomeric Chromosome End",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 614,
      "y" : 284
    },
    "minX" : 568,
    "maxX" : 646,
    "minY" : 278,
    "maxY" : 290,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 568,
        "y" : 282
      },
      "to" : {
        "x" : 614,
        "y" : 284
      }
    }, {
      "from" : {
        "x" : 614,
        "y" : 284
      },
      "to" : {
        "x" : 646,
        "y" : 285
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 639,
        "y" : 289
      },
      "b" : {
        "x" : 646,
        "y" : 285
      },
      "c" : {
        "x" : 639,
        "y" : 281
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 639,
        "y" : 281
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 608,
        "y" : 278
      },
      "b" : {
        "x" : 620,
        "y" : 290
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 614,
        "y" : 284
      }
    },
    "inputs" : [ {
      "id" : 9
    } ],
    "outputs" : [ {
      "id" : 16
    } ]
  }, {
    "id" : 3803,
    "reactomeId" : 163120,
    "displayName" : "Disassociation of Telomerase RNP and the Chromosome End",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 586,
      "y" : 750
    },
    "minX" : 505,
    "maxX" : 737,
    "minY" : 522,
    "maxY" : 756,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 737,
        "y" : 742
      },
      "to" : {
        "x" : 586,
        "y" : 750
      }
    }, {
      "from" : {
        "x" : 586,
        "y" : 750
      },
      "to" : {
        "x" : 505,
        "y" : 522
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 580,
        "y" : 744
      },
      "b" : {
        "x" : 592,
        "y" : 756
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 586,
        "y" : 750
      }
    },
    "inputs" : [ {
      "id" : 3804,
      "points" : [ {
        "x" : 755,
        "y" : 759
      } ]
    }, {
      "id" : 17,
      "points" : [ {
        "x" : 811,
        "y" : 688
      } ]
    }, {
      "id" : 3806,
      "points" : [ {
        "x" : 717,
        "y" : 760
      } ]
    } ],
    "outputs" : [ {
      "id" : 3465,
      "points" : [ {
        "x" : 548,
        "y" : 434
      } ]
    }, {
      "id" : 3807,
      "points" : [ {
        "x" : 433,
        "y" : 567
      } ]
    }, {
      "id" : 3664,
      "points" : [ {
        "x" : 460,
        "y" : 357
      } ]
    }, {
      "id" : 20,
      "points" : [ {
        "x" : 367,
        "y" : 341
      } ]
    }, {
      "id" : 3810,
      "points" : [ {
        "x" : 441,
        "y" : 611
      } ]
    }, {
      "id" : 3812,
      "points" : [ {
        "x" : 476,
        "y" : 650
      } ]
    } ],
    "catalysts" : [ {
      "id" : 3808,
      "points" : [ {
        "x" : 585,
        "y" : 802
      } ]
    } ]
  }, {
    "id" : 1564,
    "reactomeId" : 9668902,
    "displayName" : "Formation of the CTF18-RFC(7s) complex",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1274,
      "y" : 216
    },
    "minX" : 1239,
    "maxX" : 1575,
    "minY" : 211,
    "maxY" : 241,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1575,
        "y" : 214
      },
      "to" : {
        "x" : 1274,
        "y" : 216
      }
    }, {
      "from" : {
        "x" : 1274,
        "y" : 216
      },
      "to" : {
        "x" : 1239,
        "y" : 241
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1242,
        "y" : 234
      },
      "b" : {
        "x" : 1239,
        "y" : 241
      },
      "c" : {
        "x" : 1247,
        "y" : 240
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1247,
        "y" : 240
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1274,
        "y" : 216
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1274,
        "y" : 216
      }
    },
    "inputs" : [ {
      "id" : 1565,
      "points" : [ {
        "x" : 1627,
        "y" : 134
      } ]
    }, {
      "id" : 1566,
      "points" : [ {
        "x" : 1674,
        "y" : 152
      } ]
    }, {
      "id" : 1563,
      "points" : [ {
        "x" : 1448,
        "y" : 186
      } ]
    }, {
      "id" : 1567,
      "points" : [ {
        "x" : 1522,
        "y" : 133
      } ]
    }, {
      "id" : 1568,
      "points" : [ {
        "x" : 1573,
        "y" : 130
      } ]
    } ],
    "outputs" : [ {
      "id" : 1569
    } ]
  }, {
    "id" : 3615,
    "reactomeId" : 9671145,
    "displayName" : "DKC1 binds SHQ1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 193,
      "y" : 727
    },
    "minX" : 154,
    "maxX" : 250,
    "minY" : 713,
    "maxY" : 735,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 154,
        "y" : 735
      },
      "to" : {
        "x" : 193,
        "y" : 727
      }
    }, {
      "from" : {
        "x" : 193,
        "y" : 727
      },
      "to" : {
        "x" : 250,
        "y" : 713
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 244,
        "y" : 719
      },
      "b" : {
        "x" : 250,
        "y" : 713
      },
      "c" : {
        "x" : 242,
        "y" : 711
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 242,
        "y" : 711
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 193,
        "y" : 727
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 193,
        "y" : 727
      }
    },
    "inputs" : [ {
      "id" : 3,
      "points" : [ {
        "x" : 91,
        "y" : 442
      } ]
    }, {
      "id" : 3616,
      "points" : [ {
        "x" : 152,
        "y" : 807
      } ]
    } ],
    "outputs" : [ {
      "id" : 3617
    } ]
  }, {
    "id" : 32,
    "reactomeId" : 176702,
    "displayName" : "Disassociation of Processive Complex and Completed Telomere End",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1255,
      "y" : 631
    },
    "minX" : 1216,
    "maxX" : 1348,
    "minY" : 612,
    "maxY" : 650,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 1216,
        "y" : 650
      },
      "to" : {
        "x" : 1255,
        "y" : 631
      }
    }, {
      "from" : {
        "x" : 1255,
        "y" : 631
      },
      "to" : {
        "x" : 1348,
        "y" : 612
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 1255,
        "y" : 631
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 1255,
        "y" : 631
      }
    },
    "inputs" : [ {
      "id" : 31
    } ],
    "outputs" : [ {
      "id" : 28,
      "points" : [ {
        "x" : 1407,
        "y" : 593
      } ]
    }, {
      "id" : 3871,
      "points" : [ {
        "x" : 1441,
        "y" : 667
      } ]
    }, {
      "id" : 30,
      "points" : [ {
        "x" : 1583,
        "y" : 643
      } ]
    } ]
  }, {
    "id" : 3813,
    "reactomeId" : 9686521,
    "displayName" : "CDK2:CCNA phosphorylates TERF2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 247,
      "y" : 198
    },
    "minX" : 225,
    "maxX" : 274,
    "minY" : 192,
    "maxY" : 204,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 274,
        "y" : 196
      },
      "to" : {
        "x" : 247,
        "y" : 198
      }
    }, {
      "from" : {
        "x" : 247,
        "y" : 198
      },
      "to" : {
        "x" : 225,
        "y" : 194
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 241,
        "y" : 192
      },
      "b" : {
        "x" : 253,
        "y" : 204
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 247,
        "y" : 198
      }
    },
    "inputs" : [ {
      "id" : 3286,
      "points" : [ {
        "x" : 302,
        "y" : 200
      } ]
    }, {
      "id" : 3814,
      "points" : [ {
        "x" : 287,
        "y" : 166
      } ]
    } ],
    "outputs" : [ {
      "id" : 3815,
      "points" : [ {
        "x" : 183,
        "y" : 192
      } ]
    }, {
      "id" : 3816,
      "points" : [ {
        "x" : 211,
        "y" : 168
      } ]
    } ],
    "catalysts" : [ {
      "id" : 3817,
      "points" : [ {
        "x" : 244,
        "y" : 129
      } ]
    } ]
  }, {
    "id" : 422,
    "reactomeId" : 9668597,
    "displayName" : "DNA polymerase:primase binds G-strand of the telomere",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 675,
      "y" : 194
    },
    "minX" : 604,
    "maxX" : 727,
    "minY" : 187,
    "maxY" : 199,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 604,
        "y" : 187
      },
      "to" : {
        "x" : 675,
        "y" : 194
      }
    }, {
      "from" : {
        "x" : 675,
        "y" : 194
      },
      "to" : {
        "x" : 727,
        "y" : 197
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 720,
        "y" : 201
      },
      "b" : {
        "x" : 727,
        "y" : 197
      },
      "c" : {
        "x" : 720,
        "y" : 193
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 720,
        "y" : 193
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 675,
        "y" : 194
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 675,
        "y" : 194
      }
    },
    "inputs" : [ {
      "id" : 37,
      "points" : [ {
        "x" : 522,
        "y" : 122
      } ]
    }, {
      "id" : 3465,
      "points" : [ {
        "x" : 570,
        "y" : 362
      } ]
    }, {
      "id" : 583,
      "points" : [ {
        "x" : 355,
        "y" : 82
      }, {
        "x" : 407,
        "y" : 141
      } ]
    } ],
    "outputs" : [ {
      "id" : 456
    } ]
  }, {
    "id" : 39,
    "reactomeId" : 174425,
    "displayName" : "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 939,
      "y" : 200
    },
    "minX" : 899,
    "maxX" : 981,
    "minY" : 194,
    "maxY" : 221,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 899,
        "y" : 199
      },
      "to" : {
        "x" : 939,
        "y" : 200
      }
    }, {
      "from" : {
        "x" : 939,
        "y" : 200
      },
      "to" : {
        "x" : 981,
        "y" : 221
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 973,
        "y" : 221
      },
      "b" : {
        "x" : 981,
        "y" : 221
      },
      "c" : {
        "x" : 977,
        "y" : 214
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 977,
        "y" : 214
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 933,
        "y" : 194
      },
      "b" : {
        "x" : 945,
        "y" : 206
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 939,
        "y" : 200
      }
    },
    "inputs" : [ {
      "id" : 3872,
      "points" : [ {
        "x" : 892,
        "y" : 225
      } ]
    }, {
      "id" : 456,
      "points" : [ {
        "x" : 848,
        "y" : 199
      } ]
    } ],
    "outputs" : [ {
      "id" : 38
    } ],
    "catalysts" : [ {
      "id" : 456,
      "points" : [ {
        "x" : 848,
        "y" : 171
      }, {
        "x" : 884,
        "y" : 151
      } ]
    } ],
    "activators" : [ {
      "id" : 583,
      "points" : [ {
        "x" : 365,
        "y" : 52
      }, {
        "x" : 413,
        "y" : 25
      }, {
        "x" : 939,
        "y" : 50
      } ]
    } ]
  }, {
    "id" : 40,
    "reactomeId" : 174427,
    "displayName" : "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 961,
      "y" : 389
    },
    "minX" : 937,
    "maxX" : 995,
    "minY" : 357,
    "maxY" : 431,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 937,
        "y" : 357
      },
      "to" : {
        "x" : 961,
        "y" : 389
      }
    }, {
      "from" : {
        "x" : 961,
        "y" : 389
      },
      "to" : {
        "x" : 995,
        "y" : 431
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 988,
        "y" : 428
      },
      "b" : {
        "x" : 995,
        "y" : 431
      },
      "c" : {
        "x" : 994,
        "y" : 423
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 994,
        "y" : 423
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 955,
        "y" : 383
      },
      "b" : {
        "x" : 967,
        "y" : 395
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 961,
        "y" : 389
      }
    },
    "inputs" : [ {
      "id" : 2,
      "points" : [ {
        "x" : 858,
        "y" : 305
      } ]
    }, {
      "id" : 8,
      "points" : [ {
        "x" : 841,
        "y" : 341
      } ]
    }, {
      "id" : 18,
      "points" : [ {
        "x" : 786,
        "y" : 403
      } ]
    }, {
      "id" : 10,
      "points" : [ {
        "x" : 815,
        "y" : 370
      } ]
    }, {
      "id" : 38,
      "points" : [ {
        "x" : 1005,
        "y" : 281
      } ]
    } ],
    "outputs" : [ {
      "id" : 33
    } ],
    "catalysts" : [ {
      "id" : 38,
      "points" : [ {
        "x" : 1015,
        "y" : 281
      } ]
    } ]
  }, {
    "id" : 48,
    "reactomeId" : 174439,
    "displayName" : "Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1659,
      "y" : 517
    },
    "minX" : 1653,
    "maxX" : 1665,
    "minY" : 435,
    "maxY" : 561,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1664,
        "y" : 561
      },
      "to" : {
        "x" : 1659,
        "y" : 517
      }
    }, {
      "from" : {
        "x" : 1659,
        "y" : 517
      },
      "to" : {
        "x" : 1660,
        "y" : 435
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1653,
        "y" : 511
      },
      "b" : {
        "x" : 1665,
        "y" : 523
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1659,
        "y" : 517
      }
    },
    "inputs" : [ {
      "id" : 30,
      "points" : [ {
        "x" : 1638,
        "y" : 629
      } ]
    }, {
      "id" : 46,
      "points" : [ {
        "x" : 1377,
        "y" : 532
      } ]
    }, {
      "id" : 932,
      "points" : [ {
        "x" : 1681,
        "y" : 554
      } ]
    }, {
      "id" : 933,
      "points" : [ {
        "x" : 1694,
        "y" : 592
      } ]
    } ],
    "outputs" : [ {
      "id" : 43,
      "points" : [ {
        "x" : 1448,
        "y" : 290
      }, {
        "x" : 1636,
        "y" : 291
      } ]
    }, {
      "id" : 935,
      "points" : [ {
        "x" : 1689,
        "y" : 373
      } ]
    }, {
      "id" : 936,
      "points" : [ {
        "x" : 1693,
        "y" : 425
      } ]
    } ],
    "catalysts" : [ {
      "id" : 46,
      "points" : [ {
        "x" : 1377,
        "y" : 524
      } ]
    } ]
  }, {
    "id" : 49,
    "reactomeId" : 174452,
    "displayName" : "RFC binding displaces Pol Alpha on the C-strand of the telomere",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1206,
      "y" : 500
    },
    "minX" : 1200,
    "maxX" : 1212,
    "minY" : 471,
    "maxY" : 527,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 1207,
        "y" : 471
      },
      "to" : {
        "x" : 1206,
        "y" : 500
      }
    }, {
      "from" : {
        "x" : 1206,
        "y" : 500
      },
      "to" : {
        "x" : 1209,
        "y" : 527
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 1206,
        "y" : 500
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 1206,
        "y" : 500
      }
    },
    "inputs" : [ {
      "id" : 1590,
      "points" : [ {
        "x" : 1223,
        "y" : 429
      } ]
    }, {
      "id" : 33,
      "points" : [ {
        "x" : 1093,
        "y" : 472
      } ]
    } ],
    "outputs" : [ {
      "id" : 46,
      "points" : [ {
        "x" : 1243,
        "y" : 526
      } ]
    }, {
      "id" : 37,
      "points" : [ {
        "x" : 571,
        "y" : 101
      }, {
        "x" : 1141,
        "y" : 108
      }, {
        "x" : 1154,
        "y" : 526
      } ]
    }, {
      "id" : 583,
      "points" : [ {
        "x" : 400,
        "y" : 67
      }, {
        "x" : 1120,
        "y" : 82
      }, {
        "x" : 1130,
        "y" : 539
      } ]
    } ]
  }, {
    "id" : 50,
    "reactomeId" : 174448,
    "displayName" : "Formation of Processive Complex on the C-strand of the telomere",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1561,
      "y" : 610
    },
    "minX" : 1156,
    "maxX" : 1566,
    "minY" : 573,
    "maxY" : 615,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1563,
        "y" : 573
      },
      "to" : {
        "x" : 1561,
        "y" : 610
      }
    }, {
      "from" : {
        "x" : 1561,
        "y" : 610
      },
      "to" : {
        "x" : 1156,
        "y" : 591
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1163,
        "y" : 587
      },
      "b" : {
        "x" : 1156,
        "y" : 591
      },
      "c" : {
        "x" : 1163,
        "y" : 595
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1163,
        "y" : 595
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1561,
        "y" : 610
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1561,
        "y" : 610
      }
    },
    "inputs" : [ {
      "id" : 28,
      "points" : [ {
        "x" : 1527,
        "y" : 572
      } ]
    }, {
      "id" : 44,
      "points" : [ {
        "x" : 1559,
        "y" : 492
      } ]
    } ],
    "outputs" : [ {
      "id" : 42
    } ]
  }, {
    "id" : 51,
    "reactomeId" : 174447,
    "displayName" : "RFC dissociates after sliding clamp formation on the C-strand of the telomere",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1555,
      "y" : 324
    },
    "minX" : 1448,
    "maxX" : 1560,
    "minY" : 304,
    "maxY" : 373,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 1448,
        "y" : 304
      },
      "to" : {
        "x" : 1555,
        "y" : 324
      }
    }, {
      "from" : {
        "x" : 1555,
        "y" : 324
      },
      "to" : {
        "x" : 1556,
        "y" : 373
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 1555,
        "y" : 324
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 1555,
        "y" : 324
      }
    },
    "inputs" : [ {
      "id" : 43
    } ],
    "outputs" : [ {
      "id" : 1590,
      "points" : [ {
        "x" : 1289,
        "y" : 402
      } ]
    }, {
      "id" : 44,
      "points" : [ {
        "x" : 1557,
        "y" : 422
      } ]
    } ]
  }, {
    "id" : 56,
    "reactomeId" : 174456,
    "displayName" : "Joining of adjacent Okazaki fragments of the C-strand",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1154,
      "y" : 754
    },
    "minX" : 1148,
    "maxX" : 1161,
    "minY" : 714,
    "maxY" : 807,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1161,
        "y" : 807
      },
      "to" : {
        "x" : 1154,
        "y" : 754
      }
    }, {
      "from" : {
        "x" : 1154,
        "y" : 754
      },
      "to" : {
        "x" : 1151,
        "y" : 714
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1156,
        "y" : 721
      },
      "b" : {
        "x" : 1151,
        "y" : 714
      },
      "c" : {
        "x" : 1148,
        "y" : 721
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1148,
        "y" : 721
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1148,
        "y" : 748
      },
      "b" : {
        "x" : 1160,
        "y" : 760
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1154,
        "y" : 754
      }
    },
    "inputs" : [ {
      "id" : 54
    } ],
    "outputs" : [ {
      "id" : 31
    } ],
    "catalysts" : [ {
      "id" : 81,
      "points" : [ {
        "x" : 1118,
        "y" : 754
      } ]
    } ]
  }, {
    "id" : 57,
    "reactomeId" : 174444,
    "displayName" : "Formation of C-strand Okazaki fragments",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 975,
      "y" : 626
    },
    "minX" : 956,
    "maxX" : 991,
    "minY" : 555,
    "maxY" : 703,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 956,
        "y" : 555
      },
      "to" : {
        "x" : 975,
        "y" : 626
      }
    }, {
      "from" : {
        "x" : 975,
        "y" : 626
      },
      "to" : {
        "x" : 991,
        "y" : 703
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 986,
        "y" : 697
      },
      "b" : {
        "x" : 991,
        "y" : 703
      },
      "c" : {
        "x" : 994,
        "y" : 695
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 994,
        "y" : 695
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 969,
        "y" : 620
      },
      "b" : {
        "x" : 981,
        "y" : 632
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 975,
        "y" : 626
      }
    },
    "inputs" : [ {
      "id" : 2,
      "points" : [ {
        "x" : 845,
        "y" : 305
      } ]
    }, {
      "id" : 8,
      "points" : [ {
        "x" : 822,
        "y" : 354
      } ]
    }, {
      "id" : 18,
      "points" : [ {
        "x" : 780,
        "y" : 429
      } ]
    }, {
      "id" : 42,
      "points" : [ {
        "x" : 1017,
        "y" : 571
      } ]
    }, {
      "id" : 10,
      "points" : [ {
        "x" : 801,
        "y" : 390
      } ]
    } ],
    "outputs" : [ {
      "id" : 53
    } ],
    "catalysts" : [ {
      "id" : 42,
      "points" : [ {
        "x" : 1045,
        "y" : 617
      }, {
        "x" : 1016,
        "y" : 632
      } ]
    } ]
  }, {
    "id" : 2489,
    "reactomeId" : 9007926,
    "displayName" : "ATRX binds DAXX",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1789,
      "y" : 660
    },
    "minX" : 1757,
    "maxX" : 1812,
    "minY" : 616,
    "maxY" : 716,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1812,
        "y" : 616
      },
      "to" : {
        "x" : 1789,
        "y" : 660
      }
    }, {
      "from" : {
        "x" : 1789,
        "y" : 660
      },
      "to" : {
        "x" : 1757,
        "y" : 716
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1757,
        "y" : 708
      },
      "b" : {
        "x" : 1757,
        "y" : 716
      },
      "c" : {
        "x" : 1764,
        "y" : 712
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1764,
        "y" : 712
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1789,
        "y" : 660
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1789,
        "y" : 660
      }
    },
    "inputs" : [ {
      "id" : 2366,
      "points" : [ {
        "x" : 1892,
        "y" : 598
      } ]
    }, {
      "id" : 2367,
      "points" : [ {
        "x" : 1822,
        "y" : 590
      } ]
    } ],
    "outputs" : [ {
      "id" : 2368
    } ]
  }, {
    "id" : 2490,
    "reactomeId" : 9670101,
    "displayName" : "ATRX:DAXX binds to subtelomeric chromosomal regions",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1775,
      "y" : 822
    },
    "minX" : 1736,
    "maxX" : 1853,
    "minY" : 817,
    "maxY" : 827,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1736,
        "y" : 823
      },
      "to" : {
        "x" : 1775,
        "y" : 822
      }
    }, {
      "from" : {
        "x" : 1775,
        "y" : 822
      },
      "to" : {
        "x" : 1853,
        "y" : 820
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1846,
        "y" : 824
      },
      "b" : {
        "x" : 1853,
        "y" : 820
      },
      "c" : {
        "x" : 1846,
        "y" : 816
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1846,
        "y" : 816
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1775,
        "y" : 822
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1775,
        "y" : 822
      }
    },
    "inputs" : [ {
      "id" : 77,
      "points" : [ {
        "x" : 1695,
        "y" : 829
      } ]
    }, {
      "id" : 2368,
      "points" : [ {
        "x" : 1750,
        "y" : 744
      } ]
    } ],
    "outputs" : [ {
      "id" : 2458
    } ]
  }, {
    "id" : 58,
    "reactomeId" : 174438,
    "displayName" : "Formation of the Flap Intermediate on the C-strand",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 898,
      "y" : 833
    },
    "minX" : 855,
    "maxX" : 971,
    "minY" : 810,
    "maxY" : 850,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 971,
        "y" : 810
      },
      "to" : {
        "x" : 898,
        "y" : 833
      }
    }, {
      "from" : {
        "x" : 898,
        "y" : 833
      },
      "to" : {
        "x" : 855,
        "y" : 850
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 892,
        "y" : 827
      },
      "b" : {
        "x" : 904,
        "y" : 839
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 898,
        "y" : 833
      }
    },
    "inputs" : [ {
      "id" : 53,
      "points" : [ {
        "x" : 986,
        "y" : 773
      } ]
    }, {
      "id" : 1720,
      "points" : [ {
        "x" : 956,
        "y" : 828
      } ]
    }, {
      "id" : 1721,
      "points" : [ {
        "x" : 998,
        "y" : 834
      } ]
    } ],
    "outputs" : [ {
      "id" : 1755,
      "points" : [ {
        "x" : 861,
        "y" : 933
      } ]
    }, {
      "id" : 52,
      "points" : [ {
        "x" : 778,
        "y" : 853
      } ]
    }, {
      "id" : 1757,
      "points" : [ {
        "x" : 813,
        "y" : 934
      } ]
    }, {
      "id" : 1768,
      "points" : [ {
        "x" : 791,
        "y" : 898
      } ]
    } ],
    "catalysts" : [ {
      "id" : 1716,
      "points" : [ {
        "x" : 860,
        "y" : 780
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 1,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1070,
      "y" : 660
    },
    "minX" : 0,
    "maxX" : 2141,
    "minY" : 0,
    "maxY" : 1320,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 2141,
      "height" : 1320
    },
    "textPosition" : {
      "x" : 1387,
      "y" : 1222
    },
    "insets" : {
      "x" : 13,
      "y" : 9,
      "width" : 2104,
      "height" : 1290
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 26, 7, 6, 3, 20, 4, 12, 13, 14, 21, 25, 9, 27, 16, 2, 8, 10, 18, 15, 23, 11, 24, 17, 37, 39, 40, 38, 33, 43, 48, 49, 44, 46, 50, 51, 42, 28, 30, 31, 32, 52, 53, 54, 56, 57, 58, 59, 60, 63, 64, 67, 69, 70, 71, 68, 65, 61, 72, 66, 62, 79, 78, 77, 76, 73, 75, 74, 81, 202, 203, 422, 456, 579, 580, 581, 582, 583, 932, 933, 935, 936, 1559, 1560, 1561, 1562, 1563, 1564, 1565, 1566, 1567, 1568, 1569, 1590, 1591, 1716, 1720, 1721, 1755, 1757, 1768, 1871, 1872, 2366, 2367, 2368, 2445, 2446, 2458, 2489, 2490, 2614, 2615, 2616, 2627, 2772, 2773, 2774, 2775, 3286, 3465, 3615, 3616, 3617, 3664, 3803, 3804, 3806, 3807, 3808, 3810, 3812, 3813, 3814, 3815, 3816, 3817, 3866, 3867, 3868, 3870, 3871, 3872 ]
  } ],
  "notes" : [ ],
  "links" : [ {
    "id" : 1872,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 944,
      "y" : 794
    },
    "minX" : 888,
    "maxX" : 1000,
    "minY" : 780,
    "maxY" : 809,
    "segments" : [ {
      "from" : {
        "x" : 1000,
        "y" : 809
      },
      "to" : {
        "x" : 888,
        "y" : 780
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 938,
        "y" : 788
      },
      "b" : {
        "x" : 950,
        "y" : 800
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 944,
        "y" : 794
      }
    },
    "inputs" : [ {
      "id" : 1871
    } ],
    "outputs" : [ {
      "id" : 1716
    } ]
  }, {
    "id" : 1591,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 1222,
      "y" : 336
    },
    "minX" : 1216,
    "maxX" : 1228,
    "minY" : 283,
    "maxY" : 390,
    "segments" : [ {
      "from" : {
        "x" : 1218,
        "y" : 283
      },
      "to" : {
        "x" : 1226,
        "y" : 390
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1216,
        "y" : 330
      },
      "b" : {
        "x" : 1228,
        "y" : 342
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1222,
        "y" : 336
      }
    },
    "inputs" : [ {
      "id" : 1569
    } ],
    "outputs" : [ {
      "id" : 1590
    } ]
  }, {
    "id" : 2446,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 1665,
      "y" : 1032
    },
    "minX" : 1638,
    "maxX" : 1692,
    "minY" : 904,
    "maxY" : 1161,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 1638,
        "y" : 904
      },
      "to" : {
        "x" : 1692,
        "y" : 1161
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1687,
        "y" : 1155
      },
      "b" : {
        "x" : 1692,
        "y" : 1161
      },
      "c" : {
        "x" : 1694,
        "y" : 1153
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 1694,
        "y" : 1153
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1659,
        "y" : 1026
      },
      "b" : {
        "x" : 1671,
        "y" : 1038
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1665,
        "y" : 1032
      }
    },
    "inputs" : [ {
      "id" : 77
    } ],
    "outputs" : [ {
      "id" : 2445
    } ]
  } ],
  "shadows" : [ {
    "id" : 3873,
    "reactomeId" : 171306,
    "displayName" : "Packaging Of Telomere Ends",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1469,
      "y" : 860
    },
    "minX" : 1237,
    "maxX" : 1702,
    "minY" : 660,
    "maxY" : 1061,
    "prop" : {
      "x" : 1237,
      "y" : 660,
      "width" : 313,
      "height" : 401
    },
    "points" : [ {
      "x" : 1237,
      "y" : 660
    }, {
      "x" : 1702,
      "y" : 660
    }, {
      "x" : 1702,
      "y" : 1061
    }, {
      "x" : 1237,
      "y" : 1061
    } ],
    "colour" : "#4684ee"
  }, {
    "id" : 3874,
    "reactomeId" : 180786,
    "displayName" : "Extension of Telomeres",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 879,
      "y" : 639
    },
    "minX" : 9,
    "maxX" : 1750,
    "minY" : 16,
    "maxY" : 1263,
    "prop" : {
      "x" : 9,
      "y" : 16,
      "width" : 1741,
      "height" : 539
    },
    "points" : [ {
      "x" : 9,
      "y" : 16
    }, {
      "x" : 1750,
      "y" : 16
    }, {
      "x" : 1750,
      "y" : 1263
    }, {
      "x" : 9,
      "y" : 1263
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 3875,
    "reactomeId" : 9670095,
    "displayName" : "Inhibition of DNA recombination at telomere",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1813,
      "y" : 905
    },
    "minX" : 1550,
    "maxX" : 2076,
    "minY" : 555,
    "maxY" : 1256,
    "prop" : {
      "x" : 1750,
      "y" : 555,
      "width" : 326,
      "height" : 701
    },
    "points" : [ {
      "x" : 1550,
      "y" : 555
    }, {
      "x" : 2076,
      "y" : 555
    }, {
      "x" : 2076,
      "y" : 1256
    }, {
      "x" : 1550,
      "y" : 1256
    } ],
    "colour" : "#008000"
  } ],
  "minX" : 0,
  "maxX" : 2141,
  "minY" : 0,
  "maxY" : 1320,
  "disease" : true
}