{
  "dbId" : 10825953,
  "stId" : "R-GGA-1834949",
  "speciesName" : "Gallus gallus",
  "nodes" : [ {
    "dbId" : 10783909,
    "stId" : "R-GGA-3134807",
    "displayName" : "DDX41 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98408 ],
    "identifier" : "A0A8V0Y242",
    "standardIdentifier" : "uniprot:A0A8V0Y242",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "DDX41" ],
    "parents" : [ 10814680 ],
    "children" : [ ]
  }, {
    "dbId" : 10783917,
    "stId" : "R-GGA-3134947",
    "displayName" : "K48polyUb-DDX41:TRIM21 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98411 ],
    "parents" : [ ],
    "children" : [ 10766459, 10783912 ]
  }, {
    "dbId" : 10783912,
    "stId" : "R-GGA-3134942",
    "displayName" : "DDX41 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0Y242",
    "standardIdentifier" : "uniprot:A0A8V0Y242",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "DDX41" ],
    "parents" : [ 10783917 ],
    "children" : [ ]
  }, {
    "dbId" : 10783924,
    "stId" : "R-GGA-3134862",
    "displayName" : "DHX36 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98400 ],
    "identifier" : "A0A1D5PHB6",
    "standardIdentifier" : "uniprot:A0A1D5PHB6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "DHX36" ],
    "parents" : [ 10783926 ],
    "children" : [ ]
  }, {
    "dbId" : 10783926,
    "stId" : "R-GGA-3134858",
    "displayName" : "DHX36:CpG [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98402, 98404 ],
    "parents" : [ 10783928 ],
    "children" : [ 3134861, 10783924 ]
  }, {
    "dbId" : 10742457,
    "stId" : "R-GGA-168172",
    "displayName" : "RELA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0X7S8",
    "standardIdentifier" : "uniprot:A0A8V0X7S8",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10742469 ],
    "children" : [ ]
  }, {
    "dbId" : 10746169,
    "stId" : "R-GGA-166059",
    "displayName" : "MYD88 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98405 ],
    "identifier" : "A0A8V1ABC8",
    "standardIdentifier" : "uniprot:A0A8V1ABC8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MYD88" ],
    "parents" : [ 10783928 ],
    "children" : [ ]
  }, {
    "dbId" : 3244587,
    "stId" : "R-ALL-3244587",
    "displayName" : "c-GMP-AMP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 98413 ],
    "identifier" : "71501",
    "standardIdentifier" : "chebi:71501",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10784236 ],
    "children" : [ ]
  }, {
    "dbId" : 10732735,
    "stId" : "R-GGA-939205",
    "displayName" : "UBA52 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V1ACS0",
    "standardIdentifier" : "uniprot:A0A8V1ACS0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "UBA52" ],
    "parents" : [ 10732743 ],
    "children" : [ ]
  }, {
    "dbId" : 10783928,
    "stId" : "R-GGA-3134859",
    "displayName" : "DHX36:CpG:MyD88 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98454, 98406 ],
    "parents" : [ ],
    "children" : [ 10746169, 10783926 ]
  }, {
    "dbId" : 10742461,
    "stId" : "R-GGA-168168",
    "displayName" : "NFKB1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0XLT0",
    "standardIdentifier" : "uniprot:A0A8V0XLT0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NFKB1" ],
    "parents" : [ 10742467 ],
    "children" : [ ]
  }, {
    "dbId" : 10781444,
    "stId" : "R-GGA-3134799",
    "displayName" : "STING:STING [cytoplasmic vesicle membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98421 ],
    "parents" : [ 10784512, 10784523, 10784514, 10781446, 10784236 ],
    "children" : [ 10781442 ]
  }, {
    "dbId" : 10784516,
    "stId" : "R-GGA-3249369",
    "displayName" : "phospho-STAT6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98432 ],
    "identifier" : "A0A8V1A4W2",
    "standardIdentifier" : "uniprot:A0A8V1A4W2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "STAT6" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 3134861,
    "stId" : "R-ALL-3134861",
    "displayName" : "Unmethylated CpG DNA [cytosol]",
    "schemaClass" : "OtherEntity",
    "speciesId" : 0,
    "diagramIds" : [ 98401 ],
    "parents" : [ 10783926 ],
    "children" : [ ]
  }, {
    "dbId" : 10781446,
    "stId" : "R-GGA-2395983",
    "displayName" : "STING:c-di-GMP [cytoplasmic vesicle membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98392 ],
    "parents" : [ ],
    "children" : [ 2395973, 10781444 ]
  }, {
    "dbId" : 10764423,
    "stId" : "R-GGA-166267",
    "displayName" : "TBK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98423 ],
    "identifier" : "A0A8V0YQ76",
    "standardIdentifier" : "uniprot:A0A8V0YQ76",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10784523 ],
    "children" : [ ]
  }, {
    "dbId" : 10827009,
    "stId" : "R-GGA-168643",
    "displayName" : "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways",
    "schemaClass" : "Pathway",
    "speciesId" : 49591,
    "diagramIds" : [ 98497 ]
  }, {
    "dbId" : 10784512,
    "stId" : "R-GGA-3249391",
    "displayName" : "STING:p-S172-TBK1:STAT6 [cytoplasmic vesicle membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98427 ],
    "parents" : [ ],
    "children" : [ 10754939, 10742260, 10781444 ]
  }, {
    "dbId" : 10781442,
    "stId" : "R-GGA-3248021",
    "displayName" : "TMEM173 [cytoplasmic vesicle membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0YBX8",
    "standardIdentifier" : "uniprot:A0A8V0YBX8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TMEM173" ],
    "parents" : [ 10781444 ],
    "children" : [ ]
  }, {
    "dbId" : 10784514,
    "stId" : "R-GGA-2396005",
    "displayName" : "STING:p-S172-TBK1 [cytoplasmic vesicle membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98431 ],
    "parents" : [ ],
    "children" : [ 10742260, 10781444 ]
  }, {
    "dbId" : 10742284,
    "stId" : "R-GGA-450318",
    "displayName" : "phospho-IRF3 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "Q90643",
    "standardIdentifier" : "uniprot:Q90643",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IRF3" ],
    "parents" : [ 10742625 ],
    "children" : [ ]
  }, {
    "dbId" : 10784523,
    "stId" : "R-GGA-3249399",
    "displayName" : "STING:TBK1:STAT6 [cytoplasmic vesicle membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98424 ],
    "parents" : [ ],
    "children" : [ 10754939, 10764423, 10781444 ]
  }, {
    "dbId" : 10775700,
    "stId" : "R-GGA-1834940",
    "displayName" : "TMEM173 [endoplasmic reticulum membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98394 ],
    "identifier" : "A0A8V0YBX8",
    "standardIdentifier" : "uniprot:A0A8V0YBX8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TMEM173" ],
    "parents" : [ 10775702, 10781439 ],
    "children" : [ ]
  }, {
    "dbId" : 10783892,
    "stId" : "R-GGA-3134805",
    "displayName" : "TMEM173 [endoplasmic reticulum membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98395 ],
    "identifier" : "A0A8V0YBX8",
    "standardIdentifier" : "uniprot:A0A8V0YBX8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TMEM173" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10775702,
    "stId" : "R-GGA-1834963",
    "displayName" : "STING:TRIM32/TRIM56 [endoplasmic reticulum membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98417 ],
    "parents" : [ ],
    "children" : [ 10766680, 10775700 ]
  }, {
    "dbId" : 10742550,
    "stId" : "R-GGA-177674",
    "displayName" : "NFKB2 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0ZFE4",
    "standardIdentifier" : "uniprot:A0A8V0ZFE4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NFKB2" ],
    "parents" : [ 10742552 ],
    "children" : [ ]
  }, {
    "dbId" : 10742548,
    "stId" : "R-GGA-177655",
    "displayName" : "NFKB1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0XLT0",
    "standardIdentifier" : "uniprot:A0A8V0XLT0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NFKB1" ],
    "parents" : [ 10742552 ],
    "children" : [ ]
  }, {
    "dbId" : 10783901,
    "stId" : "R-GGA-3134926",
    "displayName" : "phospho-CTNNB1 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98398 ],
    "identifier" : "A0A1D5NYE8",
    "standardIdentifier" : "uniprot:A0A1D5NYE8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CTNNB1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 98384, 98435, 98377, 98426, 98430 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10742554,
    "stId" : "R-GGA-177676",
    "displayName" : "RELA [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0X7S8",
    "standardIdentifier" : "uniprot:A0A8V0X7S8",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10742556 ],
    "children" : [ ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 98433, 98386, 98437, 98379, 98428 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10783903,
    "stId" : "R-GGA-3134933",
    "displayName" : "phospho-CTNNB1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98397 ],
    "identifier" : "A0A1D5NYE8",
    "standardIdentifier" : "uniprot:A0A1D5NYE8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CTNNB1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10742552,
    "stId" : "R-GGA-177662",
    "displayName" : "Nuclear factor NF-kappa-B p50 [nucleoplasm]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49591,
    "parents" : [ 10742556 ],
    "children" : [ 10742548, 10742550 ]
  }, {
    "dbId" : 10742556,
    "stId" : "R-GGA-177673",
    "displayName" : "NFKB1(1-433), NFKB2(1-454):RELA [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98450 ],
    "parents" : [ ],
    "children" : [ 10742552, 10742554 ]
  }, {
    "dbId" : 10825957,
    "stId" : "R-GGA-168928",
    "displayName" : "DDX58/IFIH1-mediated induction of interferon-alpha/beta",
    "schemaClass" : "Pathway",
    "speciesId" : 49591,
    "diagramIds" : [ 98489 ]
  }, {
    "dbId" : 10742625,
    "stId" : "R-GGA-450344",
    "displayName" : "p-2S-IRF7:p-2S-IRF7 [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98452 ],
    "parents" : [ ],
    "children" : [ 10742284 ]
  }, {
    "dbId" : 10742501,
    "stId" : "R-GGA-177667",
    "displayName" : "phospho-CWF19L1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0XYS4",
    "standardIdentifier" : "uniprot:A0A8V0XYS4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CWF19L1" ],
    "parents" : [ 10742509 ],
    "children" : [ ]
  }, {
    "dbId" : 10742507,
    "stId" : "R-GGA-202506",
    "displayName" : "phospho-p-S177,S181-IKBKB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0YXK2",
    "standardIdentifier" : "uniprot:A0A8V0YXK2",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10742509 ],
    "children" : [ ]
  }, {
    "dbId" : 10784236,
    "stId" : "R-GGA-3244600",
    "displayName" : "STING:cGAMP [cytoplasmic vesicle membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98414 ],
    "parents" : [ ],
    "children" : [ 3244587, 10781444 ]
  }, {
    "dbId" : 8982080,
    "stId" : "R-ALL-8982080",
    "displayName" : "c-di-AMP, c-di-GMP [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 0,
    "diagramIds" : [ 98447 ],
    "parents" : [ 10814680 ],
    "children" : [ 3134845, 2395973 ]
  }, {
    "dbId" : 10783982,
    "stId" : "R-GGA-3204309",
    "displayName" : "MRE11 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98443 ],
    "identifier" : "A0A8V0Y300",
    "standardIdentifier" : "uniprot:A0A8V0Y300",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "MRE11" ],
    "parents" : [ 10783984 ],
    "children" : [ ]
  }, {
    "dbId" : 10742509,
    "stId" : "R-GGA-177663",
    "displayName" : "IKBKG:p-S176,S180-CHUK:p-S177,S181-IKBKB [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "parents" : [ ],
    "children" : [ 10742495, 10742507, 10742501 ]
  }, {
    "dbId" : 10742514,
    "stId" : "R-GGA-8952686",
    "displayName" : "NKIRAS1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0XCJ7",
    "standardIdentifier" : "uniprot:A0A8V0XCJ7",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NKIRAS1" ],
    "parents" : [ 10742520 ],
    "children" : [ ]
  }, {
    "dbId" : 10784502,
    "stId" : "R-GGA-3249376",
    "displayName" : "phospho-STAT6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98436 ],
    "identifier" : "A0A8V1A4W2",
    "standardIdentifier" : "uniprot:A0A8V1A4W2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "STAT6" ],
    "parents" : [ 10784504 ],
    "children" : [ ]
  }, {
    "dbId" : 3134845,
    "stId" : "R-ALL-3134845",
    "displayName" : "c-di-AMP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "47037",
    "standardIdentifier" : "chebi:47037",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 8982080 ],
    "children" : [ ]
  }, {
    "dbId" : 10783984,
    "stId" : "R-GGA-3204308",
    "displayName" : "MRE11:dsDNA [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98445 ],
    "parents" : [ ],
    "children" : [ 10783982, 874088 ]
  }, {
    "dbId" : 10742518,
    "stId" : "R-GGA-8952684",
    "displayName" : "NKIRAS2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "Q5ZJW6",
    "standardIdentifier" : "uniprot:Q5ZJW6",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10742520 ],
    "children" : [ ]
  }, {
    "dbId" : 10742260,
    "stId" : "R-GGA-168379",
    "displayName" : "phospho-p-S172-TBK1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0YQ76",
    "standardIdentifier" : "uniprot:A0A8V0YQ76",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10784512, 10784514 ],
    "children" : [ ]
  }, {
    "dbId" : 10784508,
    "stId" : "R-GGA-3261240",
    "displayName" : "p-S407,Y641-STAT6 dimer [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98441 ],
    "parents" : [ ],
    "children" : [ 10784506 ]
  }, {
    "dbId" : 10742520,
    "stId" : "R-GGA-8952687",
    "displayName" : "NKIRAS [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49591,
    "diagramIds" : [ 98388 ],
    "parents" : [ ],
    "children" : [ 10742518, 10742514 ]
  }, {
    "dbId" : 10781439,
    "stId" : "R-GGA-2395989",
    "displayName" : "STING:STING [endoplasmic reticulum membrane]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98391 ],
    "parents" : [ ],
    "children" : [ 10775700 ]
  }, {
    "dbId" : 10784504,
    "stId" : "R-GGA-3249385",
    "displayName" : "p-S407,Y641-STAT6 dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98439 ],
    "parents" : [ ],
    "children" : [ 10784502 ]
  }, {
    "dbId" : 10784506,
    "stId" : "R-GGA-3261241",
    "displayName" : "phospho-STAT6 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V1A4W2",
    "standardIdentifier" : "uniprot:A0A8V1A4W2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "STAT6" ],
    "parents" : [ 10784508 ],
    "children" : [ ]
  }, {
    "dbId" : 10766459,
    "stId" : "R-GGA-976051",
    "displayName" : "TRIM58 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98409 ],
    "identifier" : "A0A8V1AP69",
    "standardIdentifier" : "uniprot:A0A8V1AP69",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TRIM58" ],
    "parents" : [ 10783917 ],
    "children" : [ ]
  }, {
    "dbId" : 10754939,
    "stId" : "R-GGA-629625",
    "displayName" : "STAT6 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98422 ],
    "identifier" : "A0A8V1A4W2",
    "standardIdentifier" : "uniprot:A0A8V1A4W2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "STAT6" ],
    "parents" : [ 10784512, 10784523 ],
    "children" : [ ]
  }, {
    "dbId" : 10742467,
    "stId" : "R-GGA-177656",
    "displayName" : "NFKB1(1-433), NFKB2(1-454) [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49591,
    "parents" : [ 10742469 ],
    "children" : [ 10742461, 10742465 ]
  }, {
    "dbId" : 2395973,
    "stId" : "R-ALL-2395973",
    "displayName" : "c-di-GMP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 98390 ],
    "identifier" : "49537",
    "standardIdentifier" : "chebi:49537",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 8982080, 10781446 ],
    "children" : [ ]
  }, {
    "dbId" : 10732737,
    "stId" : "R-GGA-939214",
    "displayName" : "RPS27A [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0Z4J0",
    "standardIdentifier" : "uniprot:A0A8V0Z4J0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "RPS27A" ],
    "parents" : [ 10732743 ],
    "children" : [ ]
  }, {
    "dbId" : 10742465,
    "stId" : "R-GGA-168144",
    "displayName" : "NFKB2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0ZFE4",
    "standardIdentifier" : "uniprot:A0A8V0ZFE4",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NFKB2" ],
    "parents" : [ 10742467 ],
    "children" : [ ]
  }, {
    "dbId" : 10732743,
    "stId" : "R-GGA-113595",
    "displayName" : "Ub [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49591,
    "diagramIds" : [ 98419, 98410 ],
    "parents" : [ ],
    "children" : [ 10732737, 939879, 10732735 ]
  }, {
    "dbId" : 874088,
    "stId" : "R-ALL-874088",
    "displayName" : "Double-stranded DNA [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 98444 ],
    "identifier" : "16991",
    "standardIdentifier" : "chebi:16991",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10783984 ],
    "children" : [ ]
  }, {
    "dbId" : 10742469,
    "stId" : "R-GGA-168155",
    "displayName" : "NFKB1(1-433), NFKB2(1-454):RELA [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98385 ],
    "parents" : [ 10742481 ],
    "children" : [ 10742457, 10742467 ]
  }, {
    "dbId" : 939879,
    "stId" : "R-GGA-939879",
    "displayName" : "ubiquitin (RPS27A) [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "P79781",
    "standardIdentifier" : "uniprot:P79781",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "RPS27A", "UBA80" ],
    "parents" : [ 10732743 ],
    "children" : [ ]
  }, {
    "dbId" : 10744266,
    "stId" : "R-GGA-450270",
    "displayName" : "phospho-IRF3 [nucleoplasm]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "Q90643",
    "standardIdentifier" : "uniprot:Q90643",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IRF3" ],
    "parents" : [ 10744268 ],
    "children" : [ ]
  }, {
    "dbId" : 10742473,
    "stId" : "R-GGA-168151",
    "displayName" : "NFKBIA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0XQY0",
    "standardIdentifier" : "uniprot:A0A8V0XQY0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NFKBIA" ],
    "parents" : [ 10742479 ],
    "children" : [ ]
  }, {
    "dbId" : 10742479,
    "stId" : "R-GGA-168143",
    "displayName" : "NFkB inhibitor [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49591,
    "parents" : [ 10742481 ],
    "children" : [ 10742477, 10742473 ]
  }, {
    "dbId" : 10742477,
    "stId" : "R-GGA-168132",
    "displayName" : "NFKBIB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0XWC2",
    "standardIdentifier" : "uniprot:A0A8V0XWC2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NFKBIB" ],
    "parents" : [ 10742479 ],
    "children" : [ ]
  }, {
    "dbId" : 10744268,
    "stId" : "R-GGA-450306",
    "displayName" : "2xp-S477,S479-IRF7 [nucleoplasm]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98453 ],
    "parents" : [ ],
    "children" : [ 10744266 ]
  }, {
    "dbId" : 10742481,
    "stId" : "R-GGA-168130",
    "displayName" : "NFkB inhibitor:NFkB complex [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98383 ],
    "parents" : [ ],
    "children" : [ 10742479, 10742469 ]
  }, {
    "dbId" : 10742485,
    "stId" : "R-GGA-177677",
    "displayName" : "phospho-NFKBIA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0XQY0",
    "standardIdentifier" : "uniprot:A0A8V0XQY0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NFKBIA" ],
    "parents" : [ 10742491 ],
    "children" : [ ]
  }, {
    "dbId" : 10742491,
    "stId" : "R-GGA-177678",
    "displayName" : "Phospho-NF-kappaB Inhibitor [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 49591,
    "diagramIds" : [ 98387 ],
    "parents" : [ ],
    "children" : [ 10742489, 10742485 ]
  }, {
    "dbId" : 10742489,
    "stId" : "R-GGA-177670",
    "displayName" : "phospho-NFKBIB [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0XWC2",
    "standardIdentifier" : "uniprot:A0A8V0XWC2",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "NFKBIB" ],
    "parents" : [ 10742491 ],
    "children" : [ ]
  }, {
    "dbId" : 10766680,
    "stId" : "R-GGA-976030",
    "displayName" : "TRIM32 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "diagramIds" : [ 98416 ],
    "identifier" : "A0A8V1AKB8",
    "standardIdentifier" : "uniprot:A0A8V1AKB8",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "TRIM32" ],
    "parents" : [ 10775702 ],
    "children" : [ ]
  }, {
    "dbId" : 10742495,
    "stId" : "R-GGA-168108",
    "displayName" : "IKBKG [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 49591,
    "identifier" : "A0A8V0WZH6",
    "standardIdentifier" : "uniprot:A0A8V0WZH6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "IKBKG" ],
    "parents" : [ 10742509 ],
    "children" : [ ]
  }, {
    "dbId" : 10814680,
    "stId" : "R-GGA-9013866",
    "displayName" : "DDX41:c-di-AMP, c-di-GMP [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 49591,
    "diagramIds" : [ 98448 ],
    "parents" : [ ],
    "children" : [ 8982080, 10783909 ]
  } ],
  "edges" : [ {
    "dbId" : 10784519,
    "stId" : "R-GGA-3249371",
    "displayName" : "TBK1 phosphorylates STAT6 at Ser407",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10784529 ],
    "following" : [ 10784527 ],
    "inputs" : [ 113592, 10784512 ],
    "outputs" : [ 29370, 10784514, 10784516 ],
    "catalysts" : [ 10784512 ],
    "efs" : [ ],
    "diagramIds" : [ 98429 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10783905,
    "stId" : "R-GGA-3134914",
    "displayName" : "Beta-catenin migrates to the nucleus",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "inputs" : [ 10783903 ],
    "outputs" : [ 10783901 ],
    "efs" : [ ],
    "diagramIds" : [ 98396 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10784525,
    "stId" : "R-GGA-3249378",
    "displayName" : "STING recruits TBK1 and STAT6",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10783894 ],
    "following" : [ 10784529 ],
    "inputs" : [ 10754939, 10764423, 10781444 ],
    "outputs" : [ 10784523 ],
    "efs" : [ ],
    "diagramIds" : [ 98420 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10784238,
    "stId" : "R-GGA-3244643",
    "displayName" : "STING binds cyclic GMP-AMP",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10783894 ],
    "inputs" : [ 10781439, 3244587 ],
    "outputs" : [ 10784236 ],
    "efs" : [ ],
    "diagramIds" : [ 98412 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10784527,
    "stId" : "R-GGA-3249379",
    "displayName" : "p-S407-STAT6 is phosphorylated at Tyr641",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10784519 ],
    "following" : [ 10784521 ],
    "inputs" : [ 113592, 10784516 ],
    "outputs" : [ 29370, 10784502 ],
    "efs" : [ ],
    "diagramIds" : [ 98434 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10781448,
    "stId" : "R-GGA-2396009",
    "displayName" : "STING binds c-di-GMP",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10783894 ],
    "inputs" : [ 10781439, 2395973 ],
    "outputs" : [ 10781446 ],
    "efs" : [ ],
    "diagramIds" : [ 98389 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10784521,
    "stId" : "R-GGA-3249372",
    "displayName" : "p-S407,Y641-STAT6 is dimerized",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10784527 ],
    "following" : [ 10784510 ],
    "inputs" : [ 10784502 ],
    "outputs" : [ 10784504 ],
    "efs" : [ ],
    "diagramIds" : [ 98438 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10783894,
    "stId" : "R-GGA-3134800",
    "displayName" : "STING dimerization",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10783898 ],
    "following" : [ 10784525, 10781448, 10784238 ],
    "inputs" : [ 10775700 ],
    "outputs" : [ 10781439 ],
    "efs" : [ ],
    "activators" : [ 10783892 ],
    "diagramIds" : [ 98393 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10783920,
    "stId" : "R-GGA-3134946",
    "displayName" : "DDX41 ubiquitination by TRIM21",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10766459, 10732743, 10783909 ],
    "outputs" : [ 10783917 ],
    "catalysts" : [ 10766459 ],
    "efs" : [ ],
    "diagramIds" : [ 98407 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10784529,
    "stId" : "R-GGA-3249390",
    "displayName" : "TBK1 is phosphorylated within STING:TBK1:STAT6 complex",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10784525 ],
    "following" : [ 10784519 ],
    "inputs" : [ 10784523, 113592 ],
    "outputs" : [ 29370, 10784512 ],
    "efs" : [ ],
    "diagramIds" : [ 98425 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10783986,
    "stId" : "R-GGA-3204303",
    "displayName" : "MRE11 binds cytosolic DNA",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10783982, 874088 ],
    "outputs" : [ 10783984 ],
    "efs" : [ ],
    "diagramIds" : [ 98442 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10783932,
    "stId" : "R-GGA-3134962",
    "displayName" : "DHX36 binds DNA",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10783930 ],
    "inputs" : [ 3134861, 10783924 ],
    "outputs" : [ 10783926 ],
    "efs" : [ ],
    "diagramIds" : [ 98399 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10815965,
    "stId" : "R-GGA-9604487",
    "displayName" : "p-IRF7:p-IRF7 translocates to the nucleus",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 10742625 ],
    "outputs" : [ 10744268 ],
    "efs" : [ ],
    "activators" : [ 10783928 ],
    "diagramIds" : [ 98451 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10742522,
    "stId" : "R-GGA-168140",
    "displayName" : "Active IKK Complex phosphorylates NF-kappa-B inhibitor ",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10815963 ],
    "inputs" : [ 113592, 10742481 ],
    "outputs" : [ 29370, 10742491, 10742469 ],
    "catalysts" : [ 10742509 ],
    "efs" : [ ],
    "inhibitors" : [ 10742520 ],
    "diagramIds" : [ 98382 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10784510,
    "stId" : "R-GGA-3249370",
    "displayName" : "p-S407,Y641-STAT6 dimer migrates to the nucleus",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10784521 ],
    "inputs" : [ 10784504 ],
    "outputs" : [ 10784508 ],
    "efs" : [ ],
    "diagramIds" : [ 98440 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10775704,
    "stId" : "R-GGA-1964496",
    "displayName" : "STING binds TRIM32 or TRIM56 ",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10783898 ],
    "inputs" : [ 10766680, 10775700 ],
    "outputs" : [ 10775702 ],
    "efs" : [ ],
    "diagramIds" : [ 98415 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10783898,
    "stId" : "R-GGA-3134804",
    "displayName" : "STING ubiquitination by TRIM32 or TRIM56",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10775704 ],
    "following" : [ 10783894 ],
    "inputs" : [ 10732743, 10775702 ],
    "outputs" : [ 10766680, 10783892 ],
    "catalysts" : [ 10775702 ],
    "efs" : [ ],
    "diagramIds" : [ 98418 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10815963,
    "stId" : "R-GGA-9604480",
    "displayName" : "NFkB complex translocates from the cytosol to the nucleus",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10742522 ],
    "inputs" : [ 10742469 ],
    "outputs" : [ 10742556 ],
    "efs" : [ ],
    "diagramIds" : [ 98449 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10783930,
    "stId" : "R-GGA-3134953",
    "displayName" : "DHX36 or DHX9 binds MyD88",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10783932 ],
    "inputs" : [ 10746169, 10783926 ],
    "outputs" : [ 10783928 ],
    "efs" : [ ],
    "diagramIds" : [ 98403 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10814682,
    "stId" : "R-GGA-9013869",
    "displayName" : "DDX41 binds bacterial c-di-AMP, c-di-GMP  ",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "inputs" : [ 8982080, 10783909 ],
    "outputs" : [ 10814680 ],
    "efs" : [ ],
    "diagramIds" : [ 98446 ],
    "entityFunctionalStatus" : [ ]
  } ],
  "subpathways" : [ {
    "dbId" : 10827393,
    "stId" : "R-GGA-3134975",
    "displayName" : "Regulation of innate immune responses to cytosolic DNA",
    "events" : [ 10783920, 10775704, 10783898 ]
  }, {
    "dbId" : 10827567,
    "stId" : "R-GGA-3134963",
    "displayName" : "DEx/H-box helicases activate type I IFN and inflammatory cytokines production ",
    "events" : [ 10783932, 10815965, 10783930, 10815963 ]
  }, {
    "dbId" : 10827565,
    "stId" : "R-GGA-3134973",
    "displayName" : "LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production",
    "events" : [ 10783905 ]
  }, {
    "dbId" : 10825951,
    "stId" : "R-GGA-1606322",
    "displayName" : "ZBP1(DAI) mediated induction of type I IFNs",
    "events" : [ 10742522, 10815963 ]
  }, {
    "dbId" : 10825949,
    "stId" : "R-GGA-1810476",
    "displayName" : "RIP-mediated NFkB activation via ZBP1",
    "events" : [ 10742522, 10815963 ]
  }, {
    "dbId" : 10827481,
    "stId" : "R-GGA-1834941",
    "displayName" : "STING mediated induction of host immune responses",
    "events" : [ 10783894, 10784238, 10781448, 10784519, 10784529, 10784525, 10784510, 10784527, 10784521, 10814682 ]
  }, {
    "dbId" : 10827577,
    "stId" : "R-GGA-3249367",
    "displayName" : "STAT6-mediated induction of chemokines",
    "events" : [ 10784519, 10784529, 10784525, 10784510, 10784527, 10784521 ]
  } ]
}