{
  "dbId" : 10649766,
  "stableId" : "R-DRE-3899300",
  "displayName" : "SUMOylation of transcription cofactors",
  "nodes" : [ {
    "id" : 19328,
    "reactomeId" : 10605168,
    "displayName" : "UBE2I:SUMO2,UBE2I:SUMO3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 765,
      "y" : 245
    },
    "minX" : 695,
    "maxX" : 829,
    "minY" : 227,
    "maxY" : 292,
    "prop" : {
      "x" : 702,
      "y" : 227,
      "width" : 127,
      "height" : 36
    },
    "textPosition" : {
      "x" : 717,
      "y" : 227
    },
    "connectors" : [ {
      "edgeId" : 19327,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 738,
          "y" : 269
        },
        "to" : {
          "x" : 695,
          "y" : 292
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 710,
            "y" : 274
          },
          "b" : {
            "x" : 722,
            "y" : 286
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 716,
            "y" : 280
          }
        }
      }
    } ]
  }, {
    "id" : 19329,
    "reactomeId" : 10608571,
    "displayName" : "safb",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 743,
      "y" : 376
    },
    "minX" : 672,
    "maxX" : 807,
    "minY" : 344,
    "maxY" : 396,
    "prop" : {
      "x" : 685,
      "y" : 356,
      "width" : 116,
      "height" : 40
    },
    "textPosition" : {
      "x" : 725,
      "y" : 365
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 801,
          "y" : 356
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 801,
          "y" : 356
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19327,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 698,
          "y" : 353
        },
        "to" : {
          "x" : 672,
          "y" : 344
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 690,
          "y" : 355
        },
        "b" : {
          "x" : 698,
          "y" : 353
        },
        "c" : {
          "x" : 693,
          "y" : 347
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 693,
          "y" : 347
        }
      }
    } ]
  }, {
    "id" : 19331,
    "reactomeId" : 10607979,
    "displayName" : "ddx17",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1178,
      "y" : 55
    },
    "minX" : 1146,
    "maxX" : 1238,
    "minY" : 35,
    "maxY" : 97,
    "prop" : {
      "x" : 1146,
      "y" : 41,
      "width" : 65,
      "height" : 28
    },
    "textPosition" : {
      "x" : 1155,
      "y" : 44
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1211,
          "y" : 41
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1211,
          "y" : 41
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19330,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1198,
          "y" : 72
        },
        "to" : {
          "x" : 1238,
          "y" : 97
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19332,
    "reactomeId" : 10605072,
    "displayName" : "SUMO1:C93-UBE2I",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1288,
      "y" : 55
    },
    "minX" : 1221,
    "maxX" : 1362,
    "minY" : 36,
    "maxY" : 116,
    "prop" : {
      "x" : 1221,
      "y" : 42,
      "width" : 135,
      "height" : 26
    },
    "textPosition" : {
      "x" : 1228,
      "y" : 47
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1356,
          "y" : 42
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1356,
          "y" : 42
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19330,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1272,
          "y" : 71
        },
        "to" : {
          "x" : 1238,
          "y" : 97
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19330,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1278,
          "y" : 71
        },
        "to" : {
          "x" : 1250,
          "y" : 109
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1247,
          "y" : 112
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1247,
          "y" : 112
        }
      }
    } ]
  }, {
    "id" : 19333,
    "reactomeId" : 10607982,
    "displayName" : "ddx17",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1189,
      "y" : 190
    },
    "minX" : 1133,
    "maxX" : 1252,
    "minY" : 152,
    "maxY" : 211,
    "prop" : {
      "x" : 1133,
      "y" : 170,
      "width" : 113,
      "height" : 41
    },
    "textPosition" : {
      "x" : 1166,
      "y" : 180
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1246,
          "y" : 170
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1246,
          "y" : 170
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19330,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1217,
          "y" : 167
        },
        "to" : {
          "x" : 1242,
          "y" : 152
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1221,
          "y" : 160
        },
        "b" : {
          "x" : 1217,
          "y" : 167
        },
        "c" : {
          "x" : 1225,
          "y" : 167
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1225,
          "y" : 167
        }
      }
    } ]
  }, {
    "id" : 19334,
    "reactomeId" : 10605064,
    "displayName" : "ube2ia",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1335,
      "y" : 189
    },
    "minX" : 1242,
    "maxX" : 1372,
    "minY" : 152,
    "maxY" : 205,
    "prop" : {
      "x" : 1305,
      "y" : 173,
      "width" : 61,
      "height" : 32
    },
    "textPosition" : {
      "x" : 1310,
      "y" : 178
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1366,
          "y" : 173
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1366,
          "y" : 173
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19330,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1302,
          "y" : 176
        },
        "to" : {
          "x" : 1242,
          "y" : 152
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1294,
          "y" : 177
        },
        "b" : {
          "x" : 1302,
          "y" : 176
        },
        "c" : {
          "x" : 1297,
          "y" : 170
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1297,
          "y" : 170
        }
      }
    } ]
  }, {
    "id" : 19336,
    "reactomeId" : 10608715,
    "displayName" : "HIPK2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1186,
      "y" : 252
    },
    "minX" : 1154,
    "maxX" : 1226,
    "minY" : 231,
    "maxY" : 292,
    "prop" : {
      "x" : 1154,
      "y" : 237,
      "width" : 64,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1164,
      "y" : 241
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1218,
          "y" : 237
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1218,
          "y" : 237
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19335,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1201,
          "y" : 270
        },
        "to" : {
          "x" : 1226,
          "y" : 292
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19337,
    "reactomeId" : 10605072,
    "displayName" : "SUMO1:C93-UBE2I",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1297,
      "y" : 251
    },
    "minX" : 1226,
    "maxX" : 1372,
    "minY" : 231,
    "maxY" : 314,
    "prop" : {
      "x" : 1229,
      "y" : 237,
      "width" : 137,
      "height" : 28
    },
    "textPosition" : {
      "x" : 1237,
      "y" : 244
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1366,
          "y" : 237
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1366,
          "y" : 237
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19335,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1272,
          "y" : 268
        },
        "to" : {
          "x" : 1226,
          "y" : 292
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19335,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1282,
          "y" : 268
        },
        "to" : {
          "x" : 1238,
          "y" : 307
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1235,
          "y" : 310
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1235,
          "y" : 310
        }
      }
    } ]
  }, {
    "id" : 19338,
    "reactomeId" : 10608718,
    "displayName" : "monoSUMO1-K32-HIPK2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1167,
      "y" : 377
    },
    "minX" : 1111,
    "maxX" : 1230,
    "minY" : 341,
    "maxY" : 398,
    "prop" : {
      "x" : 1111,
      "y" : 356,
      "width" : 113,
      "height" : 42
    },
    "textPosition" : {
      "x" : 1122,
      "y" : 359
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1224,
          "y" : 356
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1224,
          "y" : 356
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19335,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1202,
          "y" : 353
        },
        "to" : {
          "x" : 1227,
          "y" : 341
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1207,
          "y" : 346
        },
        "b" : {
          "x" : 1202,
          "y" : 353
        },
        "c" : {
          "x" : 1210,
          "y" : 354
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1210,
          "y" : 354
        }
      }
    } ]
  }, {
    "id" : 19339,
    "reactomeId" : 10605064,
    "displayName" : "ube2ia",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1284,
      "y" : 375
    },
    "minX" : 1227,
    "maxX" : 1324,
    "minY" : 341,
    "maxY" : 389,
    "prop" : {
      "x" : 1251,
      "y" : 362,
      "width" : 67,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1259,
      "y" : 365
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1318,
          "y" : 362
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1318,
          "y" : 362
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19335,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1261,
          "y" : 359
        },
        "to" : {
          "x" : 1227,
          "y" : 341
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1253,
          "y" : 359
        },
        "b" : {
          "x" : 1261,
          "y" : 359
        },
        "c" : {
          "x" : 1257,
          "y" : 352
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1257,
          "y" : 352
        }
      }
    } ]
  }, {
    "id" : 19341,
    "reactomeId" : 10608603,
    "displayName" : "ING2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 603,
      "y" : 462
    },
    "minX" : 570,
    "maxX" : 664,
    "minY" : 442,
    "maxY" : 509,
    "prop" : {
      "x" : 570,
      "y" : 448,
      "width" : 67,
      "height" : 29
    },
    "textPosition" : {
      "x" : 585,
      "y" : 452
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 637,
          "y" : 448
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 637,
          "y" : 448
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19340,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 621,
          "y" : 480
        },
        "to" : {
          "x" : 664,
          "y" : 509
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19342,
    "reactomeId" : 10605072,
    "displayName" : "SUMO1:C93-UBE2I",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 720,
      "y" : 464
    },
    "minX" : 649,
    "maxX" : 798,
    "minY" : 442,
    "maxY" : 531,
    "prop" : {
      "x" : 649,
      "y" : 448,
      "width" : 143,
      "height" : 32
    },
    "textPosition" : {
      "x" : 660,
      "y" : 459
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 792,
          "y" : 448
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 792,
          "y" : 448
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19340,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 700,
          "y" : 483
        },
        "to" : {
          "x" : 664,
          "y" : 509
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19340,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 707,
          "y" : 483
        },
        "to" : {
          "x" : 675,
          "y" : 523
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 672,
          "y" : 527
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 672,
          "y" : 527
        }
      }
    } ]
  }, {
    "id" : 19343,
    "reactomeId" : 10608606,
    "displayName" : "monoSUMO1-K195-ING2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 597,
      "y" : 589
    },
    "minX" : 535,
    "maxX" : 667,
    "minY" : 556,
    "maxY" : 610,
    "prop" : {
      "x" : 535,
      "y" : 569,
      "width" : 125,
      "height" : 41
    },
    "textPosition" : {
      "x" : 552,
      "y" : 572
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 660,
          "y" : 569
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 660,
          "y" : 569
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19340,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 640,
          "y" : 566
        },
        "to" : {
          "x" : 667,
          "y" : 556
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 645,
          "y" : 560
        },
        "b" : {
          "x" : 640,
          "y" : 566
        },
        "c" : {
          "x" : 648,
          "y" : 567
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 648,
          "y" : 567
        }
      }
    } ]
  }, {
    "id" : 19344,
    "reactomeId" : 10605064,
    "displayName" : "ube2ia",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 727,
      "y" : 597
    },
    "minX" : 667,
    "maxX" : 767,
    "minY" : 556,
    "maxY" : 611,
    "prop" : {
      "x" : 694,
      "y" : 584,
      "width" : 67,
      "height" : 27
    },
    "textPosition" : {
      "x" : 702,
      "y" : 587
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 761,
          "y" : 584
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 761,
          "y" : 584
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19340,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 707,
          "y" : 581
        },
        "to" : {
          "x" : 667,
          "y" : 556
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 699,
          "y" : 581
        },
        "b" : {
          "x" : 707,
          "y" : 581
        },
        "c" : {
          "x" : 703,
          "y" : 574
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 703,
          "y" : 574
        }
      }
    } ]
  }, {
    "id" : 19346,
    "reactomeId" : 10608724,
    "displayName" : "mbd1b",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 150,
      "y" : 452
    },
    "minX" : 120,
    "maxX" : 191,
    "minY" : 432,
    "maxY" : 495,
    "prop" : {
      "x" : 120,
      "y" : 438,
      "width" : 60,
      "height" : 29
    },
    "textPosition" : {
      "x" : 124,
      "y" : 442
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 180,
          "y" : 438
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 180,
          "y" : 438
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19345,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 163,
          "y" : 470
        },
        "to" : {
          "x" : 191,
          "y" : 495
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19347,
    "reactomeId" : 10605072,
    "displayName" : "SUMO1:C93-UBE2I",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 272,
      "y" : 447
    },
    "minX" : 191,
    "maxX" : 359,
    "minY" : 424,
    "maxY" : 495,
    "prop" : {
      "x" : 208,
      "y" : 430,
      "width" : 129,
      "height" : 34
    },
    "textPosition" : {
      "x" : 212,
      "y" : 443
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 337,
          "y" : 430
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 337,
          "y" : 430
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19345,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 243,
          "y" : 467
        },
        "to" : {
          "x" : 191,
          "y" : 495
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 211,
            "y" : 475
          },
          "b" : {
            "x" : 223,
            "y" : 487
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 217,
            "y" : 481
          }
        }
      }
    }, {
      "edgeId" : 19351,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 308,
          "y" : 467
        },
        "to" : {
          "x" : 359,
          "y" : 488
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 327,
            "y" : 471
          },
          "b" : {
            "x" : 339,
            "y" : 483
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 333,
            "y" : 477
          }
        }
      }
    } ]
  }, {
    "id" : 19348,
    "reactomeId" : 10608728,
    "displayName" : "mbd1b",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 108,
      "y" : 594
    },
    "minX" : 44,
    "maxX" : 194,
    "minY" : 553,
    "maxY" : 615,
    "prop" : {
      "x" : 44,
      "y" : 573,
      "width" : 128,
      "height" : 42
    },
    "textPosition" : {
      "x" : 82,
      "y" : 583
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 172,
          "y" : 573
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 172,
          "y" : 573
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19345,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 152,
          "y" : 570
        },
        "to" : {
          "x" : 194,
          "y" : 553
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 157,
          "y" : 564
        },
        "b" : {
          "x" : 152,
          "y" : 570
        },
        "c" : {
          "x" : 160,
          "y" : 571
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 160,
          "y" : 571
        }
      }
    } ]
  }, {
    "id" : 19349,
    "reactomeId" : 10605064,
    "displayName" : "ube2ia",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 286,
      "y" : 594
    },
    "minX" : 194,
    "maxX" : 381,
    "minY" : 553,
    "maxY" : 607,
    "prop" : {
      "x" : 254,
      "y" : 582,
      "width" : 64,
      "height" : 25
    },
    "textPosition" : {
      "x" : 260,
      "y" : 584
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 318,
          "y" : 582
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 318,
          "y" : 582
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19345,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 257,
          "y" : 579
        },
        "to" : {
          "x" : 194,
          "y" : 553
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 219,
            "y" : 560
          },
          "b" : {
            "x" : 231,
            "y" : 572
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 225,
            "y" : 566
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 249,
          "y" : 580
        },
        "b" : {
          "x" : 257,
          "y" : 579
        },
        "c" : {
          "x" : 252,
          "y" : 573
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 252,
          "y" : 573
        }
      }
    }, {
      "edgeId" : 19351,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 315,
          "y" : 579
        },
        "to" : {
          "x" : 381,
          "y" : 554
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 342,
            "y" : 560
          },
          "b" : {
            "x" : 354,
            "y" : 572
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 348,
            "y" : 566
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 320,
          "y" : 573
        },
        "b" : {
          "x" : 315,
          "y" : 579
        },
        "c" : {
          "x" : 323,
          "y" : 580
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 323,
          "y" : 580
        }
      }
    } ]
  }, {
    "id" : 19350,
    "reactomeId" : 10608586,
    "displayName" : "PIAS1,3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 274,
      "y" : 520
    },
    "minX" : 197,
    "maxX" : 352,
    "minY" : 506,
    "maxY" : 534,
    "prop" : {
      "x" : 234,
      "y" : 506,
      "width" : 80,
      "height" : 28
    },
    "textPosition" : {
      "x" : 246,
      "y" : 509
    },
    "connectors" : [ {
      "edgeId" : 19345,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 228,
          "y" : 521
        },
        "to" : {
          "x" : 205,
          "y" : 522
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 201,
          "y" : 522
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 201,
          "y" : 522
        }
      }
    }, {
      "edgeId" : 19351,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 320,
          "y" : 522
        },
        "to" : {
          "x" : 344,
          "y" : 524
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 348,
          "y" : 524
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 348,
          "y" : 524
        }
      }
    } ]
  }, {
    "id" : 19352,
    "reactomeId" : 10608580,
    "displayName" : "nrip1a",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 399,
      "y" : 453
    },
    "minX" : 359,
    "maxX" : 439,
    "minY" : 434,
    "maxY" : 488,
    "prop" : {
      "x" : 365,
      "y" : 440,
      "width" : 68,
      "height" : 27
    },
    "textPosition" : {
      "x" : 375,
      "y" : 443
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 433,
          "y" : 440
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 433,
          "y" : 440
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19351,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 383,
          "y" : 470
        },
        "to" : {
          "x" : 359,
          "y" : 488
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19353,
    "reactomeId" : 10608584,
    "displayName" : "nrip1a",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 428,
      "y" : 601
    },
    "minX" : 364,
    "maxX" : 498,
    "minY" : 554,
    "maxY" : 621,
    "prop" : {
      "x" : 364,
      "y" : 582,
      "width" : 128,
      "height" : 39
    },
    "textPosition" : {
      "x" : 404,
      "y" : 591
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 492,
          "y" : 582
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 492,
          "y" : 582
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19351,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 408,
          "y" : 579
        },
        "to" : {
          "x" : 381,
          "y" : 554
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 400,
          "y" : 577
        },
        "b" : {
          "x" : 408,
          "y" : 579
        },
        "c" : {
          "x" : 406,
          "y" : 571
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 406,
          "y" : 571
        }
      }
    } ]
  }, {
    "id" : 19355,
    "reactomeId" : 10607988,
    "displayName" : "mrtfab",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1140,
      "y" : 472
    },
    "minX" : 1109,
    "maxX" : 1201,
    "minY" : 453,
    "maxY" : 514,
    "prop" : {
      "x" : 1109,
      "y" : 459,
      "width" : 63,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1116,
      "y" : 462
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1172,
          "y" : 459
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1172,
          "y" : 459
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19354,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1159,
          "y" : 489
        },
        "to" : {
          "x" : 1201,
          "y" : 514
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19356,
    "reactomeId" : 10605072,
    "displayName" : "SUMO1:C93-UBE2I",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1256,
      "y" : 472
    },
    "minX" : 1181,
    "maxX" : 1337,
    "minY" : 451,
    "maxY" : 538,
    "prop" : {
      "x" : 1181,
      "y" : 457,
      "width" : 150,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1196,
      "y" : 466
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1331,
          "y" : 457
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1331,
          "y" : 457
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19354,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1236,
          "y" : 490
        },
        "to" : {
          "x" : 1201,
          "y" : 514
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 1212,
            "y" : 496
          },
          "b" : {
            "x" : 1224,
            "y" : 508
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1218,
            "y" : 502
          }
        }
      }
    }, {
      "edgeId" : 19354,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1244,
          "y" : 490
        },
        "to" : {
          "x" : 1212,
          "y" : 530
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1209,
          "y" : 534
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1209,
          "y" : 534
        }
      }
    } ]
  }, {
    "id" : 19357,
    "reactomeId" : 10607993,
    "displayName" : "mrtfab",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1152,
      "y" : 618
    },
    "minX" : 1088,
    "maxX" : 1223,
    "minY" : 568,
    "maxY" : 641,
    "prop" : {
      "x" : 1088,
      "y" : 596,
      "width" : 129,
      "height" : 45
    },
    "textPosition" : {
      "x" : 1128,
      "y" : 608
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1217,
          "y" : 596
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1217,
          "y" : 596
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19354,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1174,
          "y" : 593
        },
        "to" : {
          "x" : 1203,
          "y" : 568
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1177,
          "y" : 585
        },
        "b" : {
          "x" : 1174,
          "y" : 593
        },
        "c" : {
          "x" : 1182,
          "y" : 592
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1182,
          "y" : 592
        }
      }
    } ]
  }, {
    "id" : 19358,
    "reactomeId" : 10605064,
    "displayName" : "ube2ia",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1283,
      "y" : 610
    },
    "minX" : 1203,
    "maxX" : 1324,
    "minY" : 568,
    "maxY" : 626,
    "prop" : {
      "x" : 1249,
      "y" : 594,
      "width" : 69,
      "height" : 32
    },
    "textPosition" : {
      "x" : 1258,
      "y" : 599
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1318,
          "y" : 594
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1318,
          "y" : 594
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19354,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1252,
          "y" : 591
        },
        "to" : {
          "x" : 1203,
          "y" : 568
        }
      } ],
      "stoichiometry" : {
        "value" : 3,
        "shape" : {
          "a" : {
            "x" : 1221,
            "y" : 573
          },
          "b" : {
            "x" : 1233,
            "y" : 585
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1227,
            "y" : 579
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1244,
          "y" : 592
        },
        "b" : {
          "x" : 1252,
          "y" : 591
        },
        "c" : {
          "x" : 1247,
          "y" : 584
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1247,
          "y" : 584
        }
      }
    } ]
  }, {
    "id" : 19360,
    "reactomeId" : 10573320,
    "displayName" : "ncoa1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 889,
      "y" : 470
    },
    "minX" : 855,
    "maxX" : 941,
    "minY" : 449,
    "maxY" : 514,
    "prop" : {
      "x" : 855,
      "y" : 455,
      "width" : 69,
      "height" : 30
    },
    "textPosition" : {
      "x" : 866,
      "y" : 459
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 924,
          "y" : 455
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 924,
          "y" : 455
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19359,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 906,
          "y" : 488
        },
        "to" : {
          "x" : 941,
          "y" : 514
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19361,
    "reactomeId" : 10605072,
    "displayName" : "SUMO1:C93-UBE2I",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1003,
      "y" : 468
    },
    "minX" : 932,
    "maxX" : 1080,
    "minY" : 447,
    "maxY" : 539,
    "prop" : {
      "x" : 932,
      "y" : 453,
      "width" : 142,
      "height" : 30
    },
    "textPosition" : {
      "x" : 943,
      "y" : 462
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1074,
          "y" : 453
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1074,
          "y" : 453
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19359,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 982,
          "y" : 486
        },
        "to" : {
          "x" : 941,
          "y" : 514
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 955,
            "y" : 494
          },
          "b" : {
            "x" : 967,
            "y" : 506
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 961,
            "y" : 500
          }
        }
      }
    }, {
      "edgeId" : 19359,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 990,
          "y" : 486
        },
        "to" : {
          "x" : 952,
          "y" : 532
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 950,
          "y" : 535
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 950,
          "y" : 535
        }
      }
    } ]
  }, {
    "id" : 19362,
    "reactomeId" : 10608543,
    "displayName" : "ncoa1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 902,
      "y" : 615
    },
    "minX" : 839,
    "maxX" : 971,
    "minY" : 570,
    "maxY" : 635,
    "prop" : {
      "x" : 839,
      "y" : 596,
      "width" : 126,
      "height" : 39
    },
    "textPosition" : {
      "x" : 878,
      "y" : 605
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 965,
          "y" : 596
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 965,
          "y" : 596
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19359,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 919,
          "y" : 593
        },
        "to" : {
          "x" : 943,
          "y" : 570
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 921,
          "y" : 585
        },
        "b" : {
          "x" : 919,
          "y" : 593
        },
        "c" : {
          "x" : 927,
          "y" : 591
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 927,
          "y" : 591
        }
      }
    } ]
  }, {
    "id" : 19363,
    "reactomeId" : 10605064,
    "displayName" : "ube2ia",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1029,
      "y" : 609
    },
    "minX" : 943,
    "maxX" : 1067,
    "minY" : 570,
    "maxY" : 624,
    "prop" : {
      "x" : 997,
      "y" : 594,
      "width" : 64,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1003,
      "y" : 598
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1061,
          "y" : 594
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1061,
          "y" : 594
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19359,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 994,
          "y" : 594
        },
        "to" : {
          "x" : 943,
          "y" : 570
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 962,
            "y" : 576
          },
          "b" : {
            "x" : 974,
            "y" : 588
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 968,
            "y" : 582
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 986,
          "y" : 595
        },
        "b" : {
          "x" : 994,
          "y" : 594
        },
        "c" : {
          "x" : 989,
          "y" : 587
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 989,
          "y" : 587
        }
      }
    } ]
  }, {
    "id" : 19365,
    "reactomeId" : 10608593,
    "displayName" : "npm1a",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 533,
      "y" : 674
    },
    "minX" : 478,
    "maxX" : 582,
    "minY" : 653,
    "maxY" : 711,
    "prop" : {
      "x" : 504,
      "y" : 659,
      "width" : 58,
      "height" : 31
    },
    "textPosition" : {
      "x" : 507,
      "y" : 664
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 562,
          "y" : 659
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 562,
          "y" : 659
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19364,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 509,
          "y" : 693
        },
        "to" : {
          "x" : 478,
          "y" : 711
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19369,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 554,
          "y" : 693
        },
        "to" : {
          "x" : 582,
          "y" : 710
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19366,
    "reactomeId" : 10605072,
    "displayName" : "SUMO1:C93-UBE2I",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 396,
      "y" : 677
    },
    "minX" : 331,
    "maxX" : 478,
    "minY" : 656,
    "maxY" : 732,
    "prop" : {
      "x" : 331,
      "y" : 662,
      "width" : 130,
      "height" : 31
    },
    "textPosition" : {
      "x" : 336,
      "y" : 672
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 461,
          "y" : 662
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 461,
          "y" : 662
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19364,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 433,
          "y" : 696
        },
        "to" : {
          "x" : 478,
          "y" : 711
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19364,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 417,
          "y" : 696
        },
        "to" : {
          "x" : 464,
          "y" : 726
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 467,
          "y" : 728
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 467,
          "y" : 728
        }
      }
    } ]
  }, {
    "id" : 19367,
    "reactomeId" : 10608611,
    "displayName" : "npm1a",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 421,
      "y" : 808
    },
    "minX" : 359,
    "maxX" : 501,
    "minY" : 761,
    "maxY" : 829,
    "prop" : {
      "x" : 359,
      "y" : 788,
      "width" : 125,
      "height" : 41
    },
    "textPosition" : {
      "x" : 396,
      "y" : 798
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 484,
          "y" : 788
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 484,
          "y" : 788
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19364,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 455,
          "y" : 785
        },
        "to" : {
          "x" : 501,
          "y" : 761
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 459,
          "y" : 778
        },
        "b" : {
          "x" : 455,
          "y" : 785
        },
        "c" : {
          "x" : 463,
          "y" : 785
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 463,
          "y" : 785
        }
      }
    } ]
  }, {
    "id" : 19368,
    "reactomeId" : 10605064,
    "displayName" : "ube2ia",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 549,
      "y" : 804
    },
    "minX" : 501,
    "maxX" : 600,
    "minY" : 754,
    "maxY" : 819,
    "prop" : {
      "x" : 514,
      "y" : 790,
      "width" : 70,
      "height" : 29
    },
    "textPosition" : {
      "x" : 523,
      "y" : 794
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 584,
          "y" : 790
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 584,
          "y" : 790
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19364,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 532,
          "y" : 787
        },
        "to" : {
          "x" : 501,
          "y" : 761
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 524,
          "y" : 786
        },
        "b" : {
          "x" : 532,
          "y" : 787
        },
        "c" : {
          "x" : 529,
          "y" : 779
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 529,
          "y" : 779
        }
      }
    }, {
      "edgeId" : 19369,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 563,
          "y" : 787
        },
        "to" : {
          "x" : 600,
          "y" : 754
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 575,
            "y" : 764
          },
          "b" : {
            "x" : 587,
            "y" : 776
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 581,
            "y" : 770
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 566,
          "y" : 779
        },
        "b" : {
          "x" : 563,
          "y" : 787
        },
        "c" : {
          "x" : 571,
          "y" : 785
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 571,
          "y" : 785
        }
      }
    } ]
  }, {
    "id" : 19370,
    "reactomeId" : 10605168,
    "displayName" : "UBE2I:SUMO2,UBE2I:SUMO3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 689,
      "y" : 672
    },
    "minX" : 582,
    "maxX" : 744,
    "minY" : 650,
    "maxY" : 730,
    "prop" : {
      "x" : 634,
      "y" : 650,
      "width" : 110,
      "height" : 44
    },
    "textPosition" : {
      "x" : 641,
      "y" : 654
    },
    "connectors" : [ {
      "edgeId" : 19369,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 628,
          "y" : 691
        },
        "to" : {
          "x" : 582,
          "y" : 710
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 599,
            "y" : 694
          },
          "b" : {
            "x" : 611,
            "y" : 706
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 605,
            "y" : 700
          }
        }
      }
    }, {
      "edgeId" : 19369,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 656,
          "y" : 700
        },
        "to" : {
          "x" : 613,
          "y" : 724
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 609,
          "y" : 726
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 609,
          "y" : 726
        }
      }
    } ]
  }, {
    "id" : 19371,
    "reactomeId" : 10608596,
    "displayName" : "npm1a",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 689,
      "y" : 806
    },
    "minX" : 600,
    "maxX" : 757,
    "minY" : 754,
    "maxY" : 832,
    "prop" : {
      "x" : 628,
      "y" : 781,
      "width" : 123,
      "height" : 51
    },
    "textPosition" : {
      "x" : 664,
      "y" : 796
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 751,
          "y" : 781
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 751,
          "y" : 781
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19369,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 645,
          "y" : 778
        },
        "to" : {
          "x" : 600,
          "y" : 754
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 637,
          "y" : 778
        },
        "b" : {
          "x" : 645,
          "y" : 778
        },
        "c" : {
          "x" : 641,
          "y" : 771
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 641,
          "y" : 771
        }
      }
    } ]
  }, {
    "id" : 19373,
    "reactomeId" : 10607733,
    "displayName" : "TRIM28:ZNF350",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 544,
      "y" : 882
    },
    "minX" : 483,
    "maxX" : 611,
    "minY" : 861,
    "maxY" : 927,
    "prop" : {
      "x" : 483,
      "y" : 867,
      "width" : 122,
      "height" : 31
    },
    "textPosition" : {
      "x" : 491,
      "y" : 877
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 605,
          "y" : 867
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 605,
          "y" : 867
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19372,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 566,
          "y" : 901
        },
        "to" : {
          "x" : 609,
          "y" : 927
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19374,
    "reactomeId" : 10605072,
    "displayName" : "SUMO1:C93-UBE2I",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 692,
      "y" : 884
    },
    "minX" : 609,
    "maxX" : 772,
    "minY" : 862,
    "maxY" : 927,
    "prop" : {
      "x" : 619,
      "y" : 868,
      "width" : 147,
      "height" : 33
    },
    "textPosition" : {
      "x" : 632,
      "y" : 880
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 766,
          "y" : 868
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 766,
          "y" : 868
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19372,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 660,
          "y" : 904
        },
        "to" : {
          "x" : 609,
          "y" : 927
        }
      } ],
      "stoichiometry" : {
        "value" : 6,
        "shape" : {
          "a" : {
            "x" : 628,
            "y" : 909
          },
          "b" : {
            "x" : 640,
            "y" : 921
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 634,
            "y" : 915
          }
        }
      }
    } ]
  }, {
    "id" : 19375,
    "reactomeId" : 10607743,
    "displayName" : "monoSUMO1-TRIM28:ZNF350",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 555,
      "y" : 1032
    },
    "minX" : 471,
    "maxX" : 645,
    "minY" : 980,
    "maxY" : 1054,
    "prop" : {
      "x" : 471,
      "y" : 1010,
      "width" : 168,
      "height" : 44
    },
    "textPosition" : {
      "x" : 485,
      "y" : 1019
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 639,
          "y" : 1010
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 639,
          "y" : 1010
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19372,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 577,
          "y" : 1007
        },
        "to" : {
          "x" : 609,
          "y" : 980
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 580,
          "y" : 999
        },
        "b" : {
          "x" : 577,
          "y" : 1007
        },
        "c" : {
          "x" : 585,
          "y" : 1006
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 585,
          "y" : 1006
        }
      }
    } ]
  }, {
    "id" : 19376,
    "reactomeId" : 10605064,
    "displayName" : "ube2ia",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 699,
      "y" : 1031
    },
    "minX" : 609,
    "maxX" : 740,
    "minY" : 980,
    "maxY" : 1047,
    "prop" : {
      "x" : 664,
      "y" : 1016,
      "width" : 70,
      "height" : 31
    },
    "textPosition" : {
      "x" : 673,
      "y" : 1021
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 734,
          "y" : 1016
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 734,
          "y" : 1016
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19372,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 671,
          "y" : 1013
        },
        "to" : {
          "x" : 609,
          "y" : 980
        }
      } ],
      "stoichiometry" : {
        "value" : 6,
        "shape" : {
          "a" : {
            "x" : 634,
            "y" : 990
          },
          "b" : {
            "x" : 646,
            "y" : 1002
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 640,
            "y" : 996
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 663,
          "y" : 1013
        },
        "b" : {
          "x" : 671,
          "y" : 1013
        },
        "c" : {
          "x" : 667,
          "y" : 1006
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 667,
          "y" : 1006
        }
      }
    } ]
  }, {
    "id" : 19377,
    "reactomeId" : 10590627,
    "displayName" : "TRIM28",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 535,
      "y" : 957
    },
    "minX" : 500,
    "maxX" : 601,
    "minY" : 937,
    "maxY" : 972,
    "prop" : {
      "x" : 500,
      "y" : 943,
      "width" : 70,
      "height" : 29
    },
    "textPosition" : {
      "x" : 509,
      "y" : 947
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 570,
          "y" : 943
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 570,
          "y" : 943
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19372,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 573,
          "y" : 956
        },
        "to" : {
          "x" : 593,
          "y" : 956
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 597,
          "y" : 956
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 597,
          "y" : 956
        }
      }
    } ]
  }, {
    "id" : 19379,
    "reactomeId" : 10606339,
    "displayName" : "Homologues of ZNF131",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 197,
      "y" : 886
    },
    "minX" : 161,
    "maxX" : 270,
    "minY" : 870,
    "maxY" : 927,
    "prop" : {
      "x" : 161,
      "y" : 870,
      "width" : 72,
      "height" : 32
    },
    "textPosition" : {
      "x" : 161,
      "y" : 862
    },
    "connectors" : [ {
      "edgeId" : 19378,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 225,
          "y" : 905
        },
        "to" : {
          "x" : 270,
          "y" : 927
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19380,
    "reactomeId" : 10605072,
    "displayName" : "SUMO1:C93-UBE2I",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 339,
      "y" : 883
    },
    "minX" : 265,
    "maxX" : 420,
    "minY" : 861,
    "maxY" : 927,
    "prop" : {
      "x" : 265,
      "y" : 867,
      "width" : 149,
      "height" : 32
    },
    "textPosition" : {
      "x" : 279,
      "y" : 878
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 414,
          "y" : 867
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 414,
          "y" : 867
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19378,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 313,
          "y" : 902
        },
        "to" : {
          "x" : 270,
          "y" : 927
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19381,
    "reactomeId" : 10606365,
    "displayName" : "Homologues of monoSUMO1-K601-ZNF131",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 175,
      "y" : 1031
    },
    "minX" : 114,
    "maxX" : 271,
    "minY" : 983,
    "maxY" : 1052,
    "prop" : {
      "x" : 114,
      "y" : 1011,
      "width" : 122,
      "height" : 41
    },
    "textPosition" : {
      "x" : 122,
      "y" : 1007
    },
    "connectors" : [ {
      "edgeId" : 19378,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 216,
          "y" : 1008
        },
        "to" : {
          "x" : 271,
          "y" : 983
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 221,
          "y" : 1001
        },
        "b" : {
          "x" : 216,
          "y" : 1008
        },
        "c" : {
          "x" : 224,
          "y" : 1009
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 224,
          "y" : 1009
        }
      }
    } ]
  }, {
    "id" : 19382,
    "reactomeId" : 10605064,
    "displayName" : "ube2ia",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 331,
      "y" : 1027
    },
    "minX" : 271,
    "maxX" : 369,
    "minY" : 983,
    "maxY" : 1042,
    "prop" : {
      "x" : 299,
      "y" : 1012,
      "width" : 64,
      "height" : 30
    },
    "textPosition" : {
      "x" : 305,
      "y" : 1016
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 363,
          "y" : 1012
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 363,
          "y" : 1012
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19378,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 310,
          "y" : 1009
        },
        "to" : {
          "x" : 271,
          "y" : 983
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 302,
          "y" : 1008
        },
        "b" : {
          "x" : 310,
          "y" : 1009
        },
        "c" : {
          "x" : 306,
          "y" : 1002
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 306,
          "y" : 1002
        }
      }
    } ]
  }, {
    "id" : 19383,
    "reactomeId" : 10605378,
    "displayName" : "cbx7a",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 180,
      "y" : 957
    },
    "minX" : 123,
    "maxX" : 261,
    "minY" : 936,
    "maxY" : 972,
    "prop" : {
      "x" : 123,
      "y" : 942,
      "width" : 115,
      "height" : 30
    },
    "textPosition" : {
      "x" : 158,
      "y" : 946
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 238,
          "y" : 942
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 238,
          "y" : 942
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19378,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 244,
          "y" : 957
        },
        "to" : {
          "x" : 253,
          "y" : 957
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 257,
          "y" : 957
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 257,
          "y" : 957
        }
      }
    } ]
  }, {
    "id" : 19299,
    "reactomeId" : 10608013,
    "displayName" : "casp8ap2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 70,
      "y" : 35
    },
    "minX" : 30,
    "maxX" : 138,
    "minY" : 15,
    "maxY" : 86,
    "prop" : {
      "x" : 30,
      "y" : 21,
      "width" : 81,
      "height" : 29
    },
    "textPosition" : {
      "x" : 35,
      "y" : 25
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 111,
          "y" : 21
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 111,
          "y" : 21
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19298,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 84,
          "y" : 53
        },
        "to" : {
          "x" : 111,
          "y" : 76
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19304,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 89,
          "y" : 53
        },
        "to" : {
          "x" : 138,
          "y" : 86
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19300,
    "reactomeId" : 10605072,
    "displayName" : "SUMO1:C93-UBE2I",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 212,
      "y" : 39
    },
    "minX" : 111,
    "maxX" : 335,
    "minY" : 19,
    "maxY" : 94,
    "prop" : {
      "x" : 146,
      "y" : 25,
      "width" : 132,
      "height" : 28
    },
    "textPosition" : {
      "x" : 152,
      "y" : 32
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 278,
          "y" : 25
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 278,
          "y" : 25
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19298,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 173,
          "y" : 56
        },
        "to" : {
          "x" : 111,
          "y" : 76
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19304,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 189,
          "y" : 56
        },
        "to" : {
          "x" : 138,
          "y" : 86
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19306,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 243,
          "y" : 56
        },
        "to" : {
          "x" : 335,
          "y" : 94
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19301,
    "reactomeId" : 10605064,
    "displayName" : "ube2ia",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 187,
      "y" : 192
    },
    "minX" : 106,
    "maxX" : 225,
    "minY" : 131,
    "maxY" : 207,
    "prop" : {
      "x" : 155,
      "y" : 177,
      "width" : 64,
      "height" : 30
    },
    "textPosition" : {
      "x" : 161,
      "y" : 181
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 219,
          "y" : 177
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 219,
          "y" : 177
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19298,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 167,
          "y" : 174
        },
        "to" : {
          "x" : 106,
          "y" : 131
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 159,
          "y" : 173
        },
        "b" : {
          "x" : 167,
          "y" : 174
        },
        "c" : {
          "x" : 164,
          "y" : 167
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 164,
          "y" : 167
        }
      }
    }, {
      "edgeId" : 19304,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 170,
          "y" : 174
        },
        "to" : {
          "x" : 122,
          "y" : 132
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 162,
          "y" : 172
        },
        "b" : {
          "x" : 170,
          "y" : 174
        },
        "c" : {
          "x" : 167,
          "y" : 166
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 167,
          "y" : 166
        }
      }
    } ]
  }, {
    "id" : 19302,
    "reactomeId" : 10608016,
    "displayName" : "casp8ap2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 80,
      "y" : 190
    },
    "minX" : 23,
    "maxX" : 144,
    "minY" : 131,
    "maxY" : 212,
    "prop" : {
      "x" : 23,
      "y" : 169,
      "width" : 115,
      "height" : 43
    },
    "textPosition" : {
      "x" : 45,
      "y" : 180
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 138,
          "y" : 169
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 138,
          "y" : 169
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19298,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 89,
          "y" : 166
        },
        "to" : {
          "x" : 106,
          "y" : 131
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 88,
          "y" : 158
        },
        "b" : {
          "x" : 89,
          "y" : 166
        },
        "c" : {
          "x" : 96,
          "y" : 162
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 96,
          "y" : 162
        }
      }
    }, {
      "edgeId" : 19304,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 95,
          "y" : 166
        },
        "to" : {
          "x" : 122,
          "y" : 132
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 96,
          "y" : 158
        },
        "b" : {
          "x" : 95,
          "y" : 166
        },
        "c" : {
          "x" : 102,
          "y" : 163
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 102,
          "y" : 163
        }
      }
    } ]
  }, {
    "id" : 19303,
    "reactomeId" : 10610806,
    "displayName" : "PIAS1,4",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 52,
      "y" : 105
    },
    "minX" : 19,
    "maxX" : 104,
    "minY" : 92,
    "maxY" : 119,
    "prop" : {
      "x" : 19,
      "y" : 92,
      "width" : 66,
      "height" : 27
    },
    "textPosition" : {
      "x" : 24,
      "y" : 95
    },
    "connectors" : [ {
      "edgeId" : 19298,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 91,
          "y" : 103
        },
        "to" : {
          "x" : 96,
          "y" : 103
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 100,
          "y" : 103
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 100,
          "y" : 103
        }
      }
    } ]
  }, {
    "id" : 19305,
    "reactomeId" : 10605386,
    "displayName" : "PRC1 complex",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 227,
      "y" : 101
    },
    "minX" : 144,
    "maxX" : 425,
    "minY" : 82,
    "maxY" : 122,
    "prop" : {
      "x" : 170,
      "y" : 88,
      "width" : 115,
      "height" : 27
    },
    "textPosition" : {
      "x" : 180,
      "y" : 94
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 285,
          "y" : 88
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 285,
          "y" : 88
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19304,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 167,
          "y" : 104
        },
        "to" : {
          "x" : 152,
          "y" : 105
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 148,
          "y" : 105
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 148,
          "y" : 105
        }
      }
    }, {
      "edgeId" : 19306,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 288,
          "y" : 111
        },
        "to" : {
          "x" : 317,
          "y" : 118
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 321,
          "y" : 118
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 321,
          "y" : 118
        }
      }
    }, {
      "edgeId" : 19310,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 288,
          "y" : 105
        },
        "to" : {
          "x" : 417,
          "y" : 117
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 421,
          "y" : 117
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 421,
          "y" : 117
        }
      }
    } ]
  }, {
    "id" : 19307,
    "reactomeId" : 10605339,
    "displayName" : "ctbp1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 381,
      "y" : 45
    },
    "minX" : 335,
    "maxX" : 431,
    "minY" : 26,
    "maxY" : 94,
    "prop" : {
      "x" : 348,
      "y" : 32,
      "width" : 67,
      "height" : 27
    },
    "textPosition" : {
      "x" : 359,
      "y" : 35
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 415,
          "y" : 32
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 415,
          "y" : 32
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19306,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 368,
          "y" : 62
        },
        "to" : {
          "x" : 335,
          "y" : 94
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19310,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 395,
          "y" : 62
        },
        "to" : {
          "x" : 431,
          "y" : 93
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19308,
    "reactomeId" : 10605392,
    "displayName" : "ctbp1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 290,
      "y" : 186
    },
    "minX" : 238,
    "maxX" : 349,
    "minY" : 143,
    "maxY" : 207,
    "prop" : {
      "x" : 238,
      "y" : 166,
      "width" : 105,
      "height" : 41
    },
    "textPosition" : {
      "x" : 268,
      "y" : 176
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 343,
          "y" : 166
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 343,
          "y" : 166
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19306,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 310,
          "y" : 163
        },
        "to" : {
          "x" : 334,
          "y" : 143
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 313,
          "y" : 155
        },
        "b" : {
          "x" : 310,
          "y" : 163
        },
        "c" : {
          "x" : 318,
          "y" : 162
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 318,
          "y" : 162
        }
      }
    } ]
  }, {
    "id" : 19309,
    "reactomeId" : 10605064,
    "displayName" : "ube2ia",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 387,
      "y" : 186
    },
    "minX" : 334,
    "maxX" : 431,
    "minY" : 139,
    "maxY" : 202,
    "prop" : {
      "x" : 357,
      "y" : 170,
      "width" : 60,
      "height" : 32
    },
    "textPosition" : {
      "x" : 361,
      "y" : 175
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 417,
          "y" : 170
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 417,
          "y" : 170
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19306,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 367,
          "y" : 167
        },
        "to" : {
          "x" : 334,
          "y" : 143
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 359,
          "y" : 166
        },
        "b" : {
          "x" : 367,
          "y" : 167
        },
        "c" : {
          "x" : 364,
          "y" : 160
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 364,
          "y" : 160
        }
      }
    }, {
      "edgeId" : 19310,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 401,
          "y" : 167
        },
        "to" : {
          "x" : 431,
          "y" : 139
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 410,
            "y" : 147
          },
          "b" : {
            "x" : 422,
            "y" : 159
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 416,
            "y" : 153
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 403,
          "y" : 159
        },
        "b" : {
          "x" : 401,
          "y" : 167
        },
        "c" : {
          "x" : 409,
          "y" : 165
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 409,
          "y" : 165
        }
      }
    } ]
  }, {
    "id" : 19311,
    "reactomeId" : 10605168,
    "displayName" : "UBE2I:SUMO2,UBE2I:SUMO3",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 550,
      "y" : 55
    },
    "minX" : 431,
    "maxX" : 606,
    "minY" : 35,
    "maxY" : 93,
    "prop" : {
      "x" : 494,
      "y" : 35,
      "width" : 112,
      "height" : 41
    },
    "textPosition" : {
      "x" : 502,
      "y" : 38
    },
    "connectors" : [ {
      "edgeId" : 19310,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 488,
          "y" : 72
        },
        "to" : {
          "x" : 431,
          "y" : 93
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 453,
            "y" : 76
          },
          "b" : {
            "x" : 465,
            "y" : 88
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 459,
            "y" : 82
          }
        }
      }
    } ]
  }, {
    "id" : 19312,
    "reactomeId" : 10605342,
    "displayName" : "ctbp1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 507,
      "y" : 189
    },
    "minX" : 431,
    "maxX" : 576,
    "minY" : 139,
    "maxY" : 207,
    "prop" : {
      "x" : 445,
      "y" : 171,
      "width" : 125,
      "height" : 36
    },
    "textPosition" : {
      "x" : 485,
      "y" : 178
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 570,
          "y" : 171
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 570,
          "y" : 171
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19310,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 479,
          "y" : 168
        },
        "to" : {
          "x" : 431,
          "y" : 139
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 471,
          "y" : 168
        },
        "b" : {
          "x" : 479,
          "y" : 168
        },
        "c" : {
          "x" : 475,
          "y" : 161
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 475,
          "y" : 161
        }
      }
    } ]
  }, {
    "id" : 19314,
    "reactomeId" : 10607999,
    "displayName" : "ddx5",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 209,
      "y" : 243
    },
    "minX" : 161,
    "maxX" : 275,
    "minY" : 222,
    "maxY" : 279,
    "prop" : {
      "x" : 177,
      "y" : 228,
      "width" : 64,
      "height" : 30
    },
    "textPosition" : {
      "x" : 190,
      "y" : 232
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 241,
          "y" : 228
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 241,
          "y" : 228
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19313,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 189,
          "y" : 261
        },
        "to" : {
          "x" : 161,
          "y" : 279
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19318,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 244,
          "y" : 255
        },
        "to" : {
          "x" : 275,
          "y" : 268
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19315,
    "reactomeId" : 10605072,
    "displayName" : "SUMO1:C93-UBE2I",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 101,
      "y" : 243
    },
    "minX" : 36,
    "maxX" : 173,
    "minY" : 221,
    "maxY" : 301,
    "prop" : {
      "x" : 36,
      "y" : 227,
      "width" : 131,
      "height" : 32
    },
    "textPosition" : {
      "x" : 41,
      "y" : 238
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 167,
          "y" : 227
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 167,
          "y" : 227
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19313,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 127,
          "y" : 262
        },
        "to" : {
          "x" : 161,
          "y" : 279
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19313,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 116,
          "y" : 262
        },
        "to" : {
          "x" : 149,
          "y" : 294
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 152,
          "y" : 297
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 152,
          "y" : 297
        }
      }
    } ]
  }, {
    "id" : 19316,
    "reactomeId" : 10608002,
    "displayName" : "ddx5",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 98,
      "y" : 374
    },
    "minX" : 41,
    "maxX" : 162,
    "minY" : 331,
    "maxY" : 396,
    "prop" : {
      "x" : 41,
      "y" : 352,
      "width" : 115,
      "height" : 44
    },
    "textPosition" : {
      "x" : 79,
      "y" : 363
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 156,
          "y" : 352
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 156,
          "y" : 352
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19313,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 130,
          "y" : 349
        },
        "to" : {
          "x" : 161,
          "y" : 331
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 134,
          "y" : 342
        },
        "b" : {
          "x" : 130,
          "y" : 349
        },
        "c" : {
          "x" : 138,
          "y" : 349
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 138,
          "y" : 349
        }
      }
    } ]
  }, {
    "id" : 19317,
    "reactomeId" : 10605064,
    "displayName" : "ube2ia",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 220,
      "y" : 365
    },
    "minX" : 161,
    "maxX" : 277,
    "minY" : 322,
    "maxY" : 380,
    "prop" : {
      "x" : 191,
      "y" : 350,
      "width" : 58,
      "height" : 30
    },
    "textPosition" : {
      "x" : 194,
      "y" : 354
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 249,
          "y" : 350
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 249,
          "y" : 350
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19313,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 193,
          "y" : 347
        },
        "to" : {
          "x" : 161,
          "y" : 331
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 185,
          "y" : 347
        },
        "b" : {
          "x" : 193,
          "y" : 347
        },
        "c" : {
          "x" : 189,
          "y" : 340
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 189,
          "y" : 340
        }
      }
    }, {
      "edgeId" : 19318,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 239,
          "y" : 347
        },
        "to" : {
          "x" : 277,
          "y" : 322
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 252,
            "y" : 328
          },
          "b" : {
            "x" : 264,
            "y" : 340
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 258,
            "y" : 334
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 243,
          "y" : 340
        },
        "b" : {
          "x" : 239,
          "y" : 347
        },
        "c" : {
          "x" : 247,
          "y" : 347
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 247,
          "y" : 347
        }
      }
    } ]
  }, {
    "id" : 19319,
    "reactomeId" : 10605158,
    "displayName" : "SUMO2:UBE2I",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 363,
      "y" : 245
    },
    "minX" : 275,
    "maxX" : 426,
    "minY" : 223,
    "maxY" : 269,
    "prop" : {
      "x" : 306,
      "y" : 229,
      "width" : 114,
      "height" : 32
    },
    "textPosition" : {
      "x" : 317,
      "y" : 240
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 420,
          "y" : 229
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 420,
          "y" : 229
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19318,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 303,
          "y" : 259
        },
        "to" : {
          "x" : 275,
          "y" : 268
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 283,
            "y" : 257
          },
          "b" : {
            "x" : 295,
            "y" : 269
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 289,
            "y" : 263
          }
        }
      }
    } ]
  }, {
    "id" : 19320,
    "reactomeId" : 10608007,
    "displayName" : "ddx5",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 362,
      "y" : 372
    },
    "minX" : 277,
    "maxX" : 422,
    "minY" : 322,
    "maxY" : 392,
    "prop" : {
      "x" : 309,
      "y" : 353,
      "width" : 107,
      "height" : 39
    },
    "textPosition" : {
      "x" : 343,
      "y" : 362
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 416,
          "y" : 353
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 416,
          "y" : 353
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19318,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 328,
          "y" : 350
        },
        "to" : {
          "x" : 277,
          "y" : 322
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 320,
          "y" : 350
        },
        "b" : {
          "x" : 328,
          "y" : 350
        },
        "c" : {
          "x" : 324,
          "y" : 343
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 324,
          "y" : 343
        }
      }
    } ]
  }, {
    "id" : 19321,
    "reactomeId" : 10589113,
    "displayName" : "pias1b",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 438,
      "y" : 311
    },
    "minX" : 283,
    "maxX" : 664,
    "minY" : 290,
    "maxY" : 327,
    "prop" : {
      "x" : 409,
      "y" : 296,
      "width" : 58,
      "height" : 31
    },
    "textPosition" : {
      "x" : 413,
      "y" : 301
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 467,
          "y" : 296
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 467,
          "y" : 296
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19318,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 406,
          "y" : 308
        },
        "to" : {
          "x" : 291,
          "y" : 298
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 287,
          "y" : 298
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 287,
          "y" : 298
        }
      }
    }, {
      "edgeId" : 19322,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 470,
          "y" : 308
        },
        "to" : {
          "x" : 560,
          "y" : 302
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 564,
          "y" : 302
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 564,
          "y" : 302
        }
      }
    }, {
      "edgeId" : 19327,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 470,
          "y" : 311
        },
        "to" : {
          "x" : 656,
          "y" : 316
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 660,
          "y" : 316
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 660,
          "y" : 316
        }
      }
    } ]
  }, {
    "id" : 19323,
    "reactomeId" : 10608556,
    "displayName" : "safb",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 627,
      "y" : 245
    },
    "minX" : 578,
    "maxX" : 695,
    "minY" : 223,
    "maxY" : 292,
    "prop" : {
      "x" : 592,
      "y" : 229,
      "width" : 70,
      "height" : 32
    },
    "textPosition" : {
      "x" : 609,
      "y" : 234
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 662,
          "y" : 229
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 662,
          "y" : 229
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19322,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 607,
          "y" : 264
        },
        "to" : {
          "x" : 578,
          "y" : 285
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 19327,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 650,
          "y" : 264
        },
        "to" : {
          "x" : 695,
          "y" : 292
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 19324,
    "reactomeId" : 10605072,
    "displayName" : "SUMO1:C93-UBE2I",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 515,
      "y" : 238
    },
    "minX" : 445,
    "maxX" : 592,
    "minY" : 219,
    "maxY" : 285,
    "prop" : {
      "x" : 445,
      "y" : 225,
      "width" : 141,
      "height" : 27
    },
    "textPosition" : {
      "x" : 455,
      "y" : 231
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 586,
          "y" : 225
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 586,
          "y" : 225
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19322,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 533,
          "y" : 255
        },
        "to" : {
          "x" : 578,
          "y" : 285
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 549,
            "y" : 264
          },
          "b" : {
            "x" : 561,
            "y" : 276
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 555,
            "y" : 270
          }
        }
      }
    } ]
  }, {
    "id" : 19325,
    "reactomeId" : 10608560,
    "displayName" : "safb",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 522,
      "y" : 372
    },
    "minX" : 465,
    "maxX" : 592,
    "minY" : 328,
    "maxY" : 394,
    "prop" : {
      "x" : 465,
      "y" : 351,
      "width" : 115,
      "height" : 43
    },
    "textPosition" : {
      "x" : 505,
      "y" : 362
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 580,
          "y" : 351
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 580,
          "y" : 351
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19322,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 556,
          "y" : 348
        },
        "to" : {
          "x" : 592,
          "y" : 328
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 560,
          "y" : 341
        },
        "b" : {
          "x" : 556,
          "y" : 348
        },
        "c" : {
          "x" : 564,
          "y" : 348
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 564,
          "y" : 348
        }
      }
    } ]
  }, {
    "id" : 19326,
    "reactomeId" : 10605064,
    "displayName" : "ube2ia",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 628,
      "y" : 373
    },
    "minX" : 592,
    "maxX" : 672,
    "minY" : 328,
    "maxY" : 388,
    "prop" : {
      "x" : 597,
      "y" : 358,
      "width" : 62,
      "height" : 30
    },
    "textPosition" : {
      "x" : 602,
      "y" : 362
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 659,
          "y" : 358
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 659,
          "y" : 358
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 19322,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 616,
          "y" : 355
        },
        "to" : {
          "x" : 592,
          "y" : 328
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 598,
            "y" : 335
          },
          "b" : {
            "x" : 610,
            "y" : 347
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 604,
            "y" : 341
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 608,
          "y" : 352
        },
        "b" : {
          "x" : 616,
          "y" : 355
        },
        "c" : {
          "x" : 614,
          "y" : 347
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 614,
          "y" : 347
        }
      }
    }, {
      "edgeId" : 19327,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 650,
          "y" : 355
        },
        "to" : {
          "x" : 672,
          "y" : 344
        }
      } ],
      "stoichiometry" : {
        "value" : 4,
        "shape" : {
          "a" : {
            "x" : 655,
            "y" : 343
          },
          "b" : {
            "x" : 667,
            "y" : 355
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 661,
            "y" : 349
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 654,
          "y" : 348
        },
        "b" : {
          "x" : 650,
          "y" : 355
        },
        "c" : {
          "x" : 658,
          "y" : 355
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 658,
          "y" : 355
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 19330,
    "reactomeId" : 10607984,
    "displayName" : "SUMOylation of DDX17 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1240,
      "y" : 122
    },
    "minX" : 1234,
    "maxX" : 1246,
    "minY" : 97,
    "maxY" : 152,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1238,
        "y" : 97
      },
      "to" : {
        "x" : 1240,
        "y" : 122
      }
    }, {
      "from" : {
        "x" : 1240,
        "y" : 122
      },
      "to" : {
        "x" : 1242,
        "y" : 152
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1234,
        "y" : 116
      },
      "b" : {
        "x" : 1246,
        "y" : 128
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1240,
        "y" : 122
      }
    },
    "inputs" : [ {
      "id" : 19331,
      "points" : [ {
        "x" : 1198,
        "y" : 72
      } ]
    }, {
      "id" : 19332,
      "points" : [ {
        "x" : 1272,
        "y" : 71
      } ]
    } ],
    "outputs" : [ {
      "id" : 19333,
      "points" : [ {
        "x" : 1217,
        "y" : 167
      } ]
    }, {
      "id" : 19334,
      "points" : [ {
        "x" : 1302,
        "y" : 176
      } ]
    } ],
    "catalysts" : [ {
      "id" : 19332,
      "points" : [ {
        "x" : 1278,
        "y" : 71
      } ]
    } ]
  }, {
    "id" : 19298,
    "reactomeId" : 10610809,
    "displayName" : "PIAS1,4 SUMOylate CASP8AP2 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 112,
      "y" : 103
    },
    "minX" : 106,
    "maxX" : 118,
    "minY" : 76,
    "maxY" : 131,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 111,
        "y" : 76
      },
      "to" : {
        "x" : 112,
        "y" : 103
      }
    }, {
      "from" : {
        "x" : 112,
        "y" : 103
      },
      "to" : {
        "x" : 106,
        "y" : 131
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 106,
        "y" : 97
      },
      "b" : {
        "x" : 118,
        "y" : 109
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 112,
        "y" : 103
      }
    },
    "inputs" : [ {
      "id" : 19299,
      "points" : [ {
        "x" : 84,
        "y" : 53
      } ]
    }, {
      "id" : 19300,
      "points" : [ {
        "x" : 173,
        "y" : 56
      } ]
    } ],
    "outputs" : [ {
      "id" : 19301,
      "points" : [ {
        "x" : 167,
        "y" : 174
      } ]
    }, {
      "id" : 19302,
      "points" : [ {
        "x" : 89,
        "y" : 166
      } ]
    } ],
    "catalysts" : [ {
      "id" : 19303,
      "points" : [ {
        "x" : 91,
        "y" : 103
      } ]
    } ]
  }, {
    "id" : 19364,
    "reactomeId" : 10608613,
    "displayName" : "SUMOylation of NPM1 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 477,
      "y" : 735
    },
    "minX" : 471,
    "maxX" : 501,
    "minY" : 711,
    "maxY" : 761,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 478,
        "y" : 711
      },
      "to" : {
        "x" : 477,
        "y" : 735
      }
    }, {
      "from" : {
        "x" : 477,
        "y" : 735
      },
      "to" : {
        "x" : 501,
        "y" : 761
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 471,
        "y" : 729
      },
      "b" : {
        "x" : 483,
        "y" : 741
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 477,
        "y" : 735
      }
    },
    "inputs" : [ {
      "id" : 19365,
      "points" : [ {
        "x" : 509,
        "y" : 693
      } ]
    }, {
      "id" : 19366,
      "points" : [ {
        "x" : 433,
        "y" : 696
      } ]
    } ],
    "outputs" : [ {
      "id" : 19367,
      "points" : [ {
        "x" : 455,
        "y" : 785
      } ]
    }, {
      "id" : 19368,
      "points" : [ {
        "x" : 532,
        "y" : 787
      } ]
    } ],
    "catalysts" : [ {
      "id" : 19366,
      "points" : [ {
        "x" : 417,
        "y" : 696
      } ]
    } ]
  }, {
    "id" : 19335,
    "reactomeId" : 10608720,
    "displayName" : "SUMOylation of HIPK2 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1226,
      "y" : 318
    },
    "minX" : 1220,
    "maxX" : 1232,
    "minY" : 292,
    "maxY" : 341,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1226,
        "y" : 292
      },
      "to" : {
        "x" : 1226,
        "y" : 318
      }
    }, {
      "from" : {
        "x" : 1226,
        "y" : 318
      },
      "to" : {
        "x" : 1227,
        "y" : 341
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1220,
        "y" : 312
      },
      "b" : {
        "x" : 1232,
        "y" : 324
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1226,
        "y" : 318
      }
    },
    "inputs" : [ {
      "id" : 19336,
      "points" : [ {
        "x" : 1201,
        "y" : 270
      } ]
    }, {
      "id" : 19337,
      "points" : [ {
        "x" : 1272,
        "y" : 268
      } ]
    } ],
    "outputs" : [ {
      "id" : 19338,
      "points" : [ {
        "x" : 1202,
        "y" : 353
      } ]
    }, {
      "id" : 19339,
      "points" : [ {
        "x" : 1261,
        "y" : 359
      } ]
    } ],
    "catalysts" : [ {
      "id" : 19337,
      "points" : [ {
        "x" : 1282,
        "y" : 268
      } ]
    } ]
  }, {
    "id" : 19304,
    "reactomeId" : 10608018,
    "displayName" : "PRC1 SUMOylates CASP8AP2 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 136,
      "y" : 106
    },
    "minX" : 122,
    "maxX" : 142,
    "minY" : 86,
    "maxY" : 132,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 138,
        "y" : 86
      },
      "to" : {
        "x" : 136,
        "y" : 106
      }
    }, {
      "from" : {
        "x" : 136,
        "y" : 106
      },
      "to" : {
        "x" : 122,
        "y" : 132
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 130,
        "y" : 100
      },
      "b" : {
        "x" : 142,
        "y" : 112
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 136,
        "y" : 106
      }
    },
    "inputs" : [ {
      "id" : 19299,
      "points" : [ {
        "x" : 89,
        "y" : 53
      } ]
    }, {
      "id" : 19300,
      "points" : [ {
        "x" : 189,
        "y" : 56
      } ]
    } ],
    "outputs" : [ {
      "id" : 19301,
      "points" : [ {
        "x" : 170,
        "y" : 174
      } ]
    }, {
      "id" : 19302,
      "points" : [ {
        "x" : 95,
        "y" : 166
      } ]
    } ],
    "catalysts" : [ {
      "id" : 19305,
      "points" : [ {
        "x" : 167,
        "y" : 104
      } ]
    } ]
  }, {
    "id" : 19369,
    "reactomeId" : 10608599,
    "displayName" : "SUMOylation of NPM1 with SUMO2,3",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 599,
      "y" : 732
    },
    "minX" : 582,
    "maxX" : 605,
    "minY" : 710,
    "maxY" : 754,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 582,
        "y" : 710
      },
      "to" : {
        "x" : 599,
        "y" : 732
      }
    }, {
      "from" : {
        "x" : 599,
        "y" : 732
      },
      "to" : {
        "x" : 600,
        "y" : 754
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 593,
        "y" : 726
      },
      "b" : {
        "x" : 605,
        "y" : 738
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 599,
        "y" : 732
      }
    },
    "inputs" : [ {
      "id" : 19365,
      "points" : [ {
        "x" : 554,
        "y" : 693
      } ]
    }, {
      "id" : 19370,
      "points" : [ {
        "x" : 628,
        "y" : 691
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 19371,
      "points" : [ {
        "x" : 645,
        "y" : 778
      } ]
    }, {
      "id" : 19368,
      "points" : [ {
        "x" : 563,
        "y" : 787
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 19370,
      "points" : [ {
        "x" : 656,
        "y" : 700
      } ]
    } ]
  }, {
    "id" : 19306,
    "reactomeId" : 10605394,
    "displayName" : "PRC1 SUMOylates CTBP1 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 333,
      "y" : 121
    },
    "minX" : 327,
    "maxX" : 339,
    "minY" : 94,
    "maxY" : 143,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 335,
        "y" : 94
      },
      "to" : {
        "x" : 333,
        "y" : 121
      }
    }, {
      "from" : {
        "x" : 333,
        "y" : 121
      },
      "to" : {
        "x" : 334,
        "y" : 143
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 327,
        "y" : 115
      },
      "b" : {
        "x" : 339,
        "y" : 127
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 333,
        "y" : 121
      }
    },
    "inputs" : [ {
      "id" : 19307,
      "points" : [ {
        "x" : 368,
        "y" : 62
      } ]
    }, {
      "id" : 19300,
      "points" : [ {
        "x" : 243,
        "y" : 56
      } ]
    } ],
    "outputs" : [ {
      "id" : 19308,
      "points" : [ {
        "x" : 310,
        "y" : 163
      } ]
    }, {
      "id" : 19309,
      "points" : [ {
        "x" : 367,
        "y" : 167
      } ]
    } ],
    "catalysts" : [ {
      "id" : 19305,
      "points" : [ {
        "x" : 288,
        "y" : 111
      } ]
    } ]
  }, {
    "id" : 19340,
    "reactomeId" : 10608608,
    "displayName" : "SUMOylation of ING2 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 665,
      "y" : 536
    },
    "minX" : 659,
    "maxX" : 671,
    "minY" : 509,
    "maxY" : 556,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 664,
        "y" : 509
      },
      "to" : {
        "x" : 665,
        "y" : 536
      }
    }, {
      "from" : {
        "x" : 665,
        "y" : 536
      },
      "to" : {
        "x" : 667,
        "y" : 556
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 659,
        "y" : 530
      },
      "b" : {
        "x" : 671,
        "y" : 542
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 665,
        "y" : 536
      }
    },
    "inputs" : [ {
      "id" : 19341,
      "points" : [ {
        "x" : 621,
        "y" : 480
      } ]
    }, {
      "id" : 19342,
      "points" : [ {
        "x" : 700,
        "y" : 483
      } ]
    } ],
    "outputs" : [ {
      "id" : 19343,
      "points" : [ {
        "x" : 640,
        "y" : 566
      } ]
    }, {
      "id" : 19344,
      "points" : [ {
        "x" : 707,
        "y" : 581
      } ]
    } ],
    "catalysts" : [ {
      "id" : 19342,
      "points" : [ {
        "x" : 707,
        "y" : 483
      } ]
    } ]
  }, {
    "id" : 19372,
    "reactomeId" : 10607746,
    "displayName" : "TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 609,
      "y" : 956
    },
    "minX" : 603,
    "maxX" : 615,
    "minY" : 927,
    "maxY" : 980,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 609,
        "y" : 927
      },
      "to" : {
        "x" : 609,
        "y" : 956
      }
    }, {
      "from" : {
        "x" : 609,
        "y" : 956
      },
      "to" : {
        "x" : 609,
        "y" : 980
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 603,
        "y" : 950
      },
      "b" : {
        "x" : 615,
        "y" : 962
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 609,
        "y" : 956
      }
    },
    "inputs" : [ {
      "id" : 19373,
      "points" : [ {
        "x" : 566,
        "y" : 901
      } ]
    }, {
      "id" : 19374,
      "points" : [ {
        "x" : 660,
        "y" : 904
      } ],
      "stoichiometry" : 6
    } ],
    "outputs" : [ {
      "id" : 19375,
      "points" : [ {
        "x" : 577,
        "y" : 1007
      } ]
    }, {
      "id" : 19376,
      "points" : [ {
        "x" : 671,
        "y" : 1013
      } ],
      "stoichiometry" : 6
    } ],
    "catalysts" : [ {
      "id" : 19377,
      "points" : [ {
        "x" : 573,
        "y" : 956
      } ]
    } ]
  }, {
    "id" : 19310,
    "reactomeId" : 10605389,
    "displayName" : "PRC1 SUMOylates CTBP1 with SUMO2,3",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 433,
      "y" : 118
    },
    "minX" : 427,
    "maxX" : 439,
    "minY" : 93,
    "maxY" : 139,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 431,
        "y" : 93
      },
      "to" : {
        "x" : 433,
        "y" : 118
      }
    }, {
      "from" : {
        "x" : 433,
        "y" : 118
      },
      "to" : {
        "x" : 431,
        "y" : 139
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 427,
        "y" : 112
      },
      "b" : {
        "x" : 439,
        "y" : 124
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 433,
        "y" : 118
      }
    },
    "inputs" : [ {
      "id" : 19311,
      "points" : [ {
        "x" : 488,
        "y" : 72
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 19307,
      "points" : [ {
        "x" : 395,
        "y" : 62
      } ]
    } ],
    "outputs" : [ {
      "id" : 19312,
      "points" : [ {
        "x" : 479,
        "y" : 168
      } ]
    }, {
      "id" : 19309,
      "points" : [ {
        "x" : 401,
        "y" : 167
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 19305,
      "points" : [ {
        "x" : 288,
        "y" : 105
      } ]
    } ]
  }, {
    "id" : 19313,
    "reactomeId" : 10608004,
    "displayName" : "SUMOylation of DDX5 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 161,
      "y" : 305
    },
    "minX" : 155,
    "maxX" : 167,
    "minY" : 279,
    "maxY" : 331,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 161,
        "y" : 279
      },
      "to" : {
        "x" : 161,
        "y" : 305
      }
    }, {
      "from" : {
        "x" : 161,
        "y" : 305
      },
      "to" : {
        "x" : 161,
        "y" : 331
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 155,
        "y" : 299
      },
      "b" : {
        "x" : 167,
        "y" : 311
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 161,
        "y" : 305
      }
    },
    "inputs" : [ {
      "id" : 19314,
      "points" : [ {
        "x" : 189,
        "y" : 261
      } ]
    }, {
      "id" : 19315,
      "points" : [ {
        "x" : 127,
        "y" : 262
      } ]
    } ],
    "outputs" : [ {
      "id" : 19316,
      "points" : [ {
        "x" : 130,
        "y" : 349
      } ]
    }, {
      "id" : 19317,
      "points" : [ {
        "x" : 193,
        "y" : 347
      } ]
    } ],
    "catalysts" : [ {
      "id" : 19315,
      "points" : [ {
        "x" : 116,
        "y" : 262
      } ]
    } ]
  }, {
    "id" : 19345,
    "reactomeId" : 10608730,
    "displayName" : "PIAS1,3 SUMOylate MBD1 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 189,
      "y" : 523
    },
    "minX" : 183,
    "maxX" : 195,
    "minY" : 495,
    "maxY" : 553,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 191,
        "y" : 495
      },
      "to" : {
        "x" : 189,
        "y" : 523
      }
    }, {
      "from" : {
        "x" : 189,
        "y" : 523
      },
      "to" : {
        "x" : 194,
        "y" : 553
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 183,
        "y" : 517
      },
      "b" : {
        "x" : 195,
        "y" : 529
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 189,
        "y" : 523
      }
    },
    "inputs" : [ {
      "id" : 19346,
      "points" : [ {
        "x" : 163,
        "y" : 470
      } ]
    }, {
      "id" : 19347,
      "points" : [ {
        "x" : 243,
        "y" : 467
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 19348,
      "points" : [ {
        "x" : 152,
        "y" : 570
      } ]
    }, {
      "id" : 19349,
      "points" : [ {
        "x" : 257,
        "y" : 579
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 19350,
      "points" : [ {
        "x" : 228,
        "y" : 521
      } ]
    } ]
  }, {
    "id" : 19378,
    "reactomeId" : 10606368,
    "displayName" : "CBX4, UHRF2 SUMOylate ZNF131 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 269,
      "y" : 957
    },
    "minX" : 263,
    "maxX" : 275,
    "minY" : 927,
    "maxY" : 983,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 270,
        "y" : 927
      },
      "to" : {
        "x" : 269,
        "y" : 957
      }
    }, {
      "from" : {
        "x" : 269,
        "y" : 957
      },
      "to" : {
        "x" : 271,
        "y" : 983
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 263,
        "y" : 951
      },
      "b" : {
        "x" : 275,
        "y" : 963
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 269,
        "y" : 957
      }
    },
    "inputs" : [ {
      "id" : 19379,
      "points" : [ {
        "x" : 225,
        "y" : 905
      } ]
    }, {
      "id" : 19380,
      "points" : [ {
        "x" : 313,
        "y" : 902
      } ]
    } ],
    "outputs" : [ {
      "id" : 19381,
      "points" : [ {
        "x" : 216,
        "y" : 1008
      } ]
    }, {
      "id" : 19382,
      "points" : [ {
        "x" : 310,
        "y" : 1009
      } ]
    } ],
    "catalysts" : [ {
      "id" : 19383,
      "points" : [ {
        "x" : 244,
        "y" : 957
      } ]
    } ]
  }, {
    "id" : 19318,
    "reactomeId" : 10608009,
    "displayName" : "PIAS1 SUMOylates DDX5 with SUMO2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 275,
      "y" : 297
    },
    "minX" : 269,
    "maxX" : 281,
    "minY" : 268,
    "maxY" : 322,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 275,
        "y" : 268
      },
      "to" : {
        "x" : 275,
        "y" : 297
      }
    }, {
      "from" : {
        "x" : 275,
        "y" : 297
      },
      "to" : {
        "x" : 277,
        "y" : 322
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 269,
        "y" : 291
      },
      "b" : {
        "x" : 281,
        "y" : 303
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 275,
        "y" : 297
      }
    },
    "inputs" : [ {
      "id" : 19319,
      "points" : [ {
        "x" : 303,
        "y" : 259
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 19314,
      "points" : [ {
        "x" : 244,
        "y" : 255
      } ]
    } ],
    "outputs" : [ {
      "id" : 19320,
      "points" : [ {
        "x" : 328,
        "y" : 350
      } ]
    }, {
      "id" : 19317,
      "points" : [ {
        "x" : 239,
        "y" : 347
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 19321,
      "points" : [ {
        "x" : 406,
        "y" : 308
      } ]
    } ]
  }, {
    "id" : 19351,
    "reactomeId" : 10608589,
    "displayName" : "PIAS1,3 SUMOylate NRIP1 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 360,
      "y" : 525
    },
    "minX" : 354,
    "maxX" : 381,
    "minY" : 488,
    "maxY" : 554,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 359,
        "y" : 488
      },
      "to" : {
        "x" : 360,
        "y" : 525
      }
    }, {
      "from" : {
        "x" : 360,
        "y" : 525
      },
      "to" : {
        "x" : 381,
        "y" : 554
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 354,
        "y" : 519
      },
      "b" : {
        "x" : 366,
        "y" : 531
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 360,
        "y" : 525
      }
    },
    "inputs" : [ {
      "id" : 19352,
      "points" : [ {
        "x" : 383,
        "y" : 470
      } ]
    }, {
      "id" : 19347,
      "points" : [ {
        "x" : 308,
        "y" : 467
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 19353,
      "points" : [ {
        "x" : 408,
        "y" : 579
      } ]
    }, {
      "id" : 19349,
      "points" : [ {
        "x" : 315,
        "y" : 579
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 19350,
      "points" : [ {
        "x" : 320,
        "y" : 522
      } ]
    } ]
  }, {
    "id" : 19322,
    "reactomeId" : 10608562,
    "displayName" : "PIAS1 SUMOylates SAFB with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 576,
      "y" : 301
    },
    "minX" : 570,
    "maxX" : 592,
    "minY" : 285,
    "maxY" : 328,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 578,
        "y" : 285
      },
      "to" : {
        "x" : 576,
        "y" : 301
      }
    }, {
      "from" : {
        "x" : 576,
        "y" : 301
      },
      "to" : {
        "x" : 592,
        "y" : 328
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 570,
        "y" : 295
      },
      "b" : {
        "x" : 582,
        "y" : 307
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 576,
        "y" : 301
      }
    },
    "inputs" : [ {
      "id" : 19323,
      "points" : [ {
        "x" : 607,
        "y" : 264
      } ]
    }, {
      "id" : 19324,
      "points" : [ {
        "x" : 533,
        "y" : 255
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 19325,
      "points" : [ {
        "x" : 556,
        "y" : 348
      } ]
    }, {
      "id" : 19326,
      "points" : [ {
        "x" : 616,
        "y" : 355
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 19321,
      "points" : [ {
        "x" : 470,
        "y" : 308
      } ]
    } ]
  }, {
    "id" : 19354,
    "reactomeId" : 10607995,
    "displayName" : "SUMOylation of MKL1 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1202,
      "y" : 543
    },
    "minX" : 1196,
    "maxX" : 1208,
    "minY" : 514,
    "maxY" : 568,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1201,
        "y" : 514
      },
      "to" : {
        "x" : 1202,
        "y" : 543
      }
    }, {
      "from" : {
        "x" : 1202,
        "y" : 543
      },
      "to" : {
        "x" : 1203,
        "y" : 568
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1196,
        "y" : 537
      },
      "b" : {
        "x" : 1208,
        "y" : 549
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1202,
        "y" : 543
      }
    },
    "inputs" : [ {
      "id" : 19355,
      "points" : [ {
        "x" : 1159,
        "y" : 489
      } ]
    }, {
      "id" : 19356,
      "points" : [ {
        "x" : 1236,
        "y" : 490
      } ],
      "stoichiometry" : 3
    } ],
    "outputs" : [ {
      "id" : 19357,
      "points" : [ {
        "x" : 1174,
        "y" : 593
      } ]
    }, {
      "id" : 19358,
      "points" : [ {
        "x" : 1252,
        "y" : 591
      } ],
      "stoichiometry" : 3
    } ],
    "catalysts" : [ {
      "id" : 19356,
      "points" : [ {
        "x" : 1244,
        "y" : 490
      } ]
    } ]
  }, {
    "id" : 19359,
    "reactomeId" : 10608545,
    "displayName" : "SUMOylation of NCOA1 with SUMO1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 942,
      "y" : 544
    },
    "minX" : 936,
    "maxX" : 948,
    "minY" : 514,
    "maxY" : 570,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 941,
        "y" : 514
      },
      "to" : {
        "x" : 942,
        "y" : 544
      }
    }, {
      "from" : {
        "x" : 942,
        "y" : 544
      },
      "to" : {
        "x" : 943,
        "y" : 570
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 936,
        "y" : 538
      },
      "b" : {
        "x" : 948,
        "y" : 550
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 942,
        "y" : 544
      }
    },
    "inputs" : [ {
      "id" : 19360,
      "points" : [ {
        "x" : 906,
        "y" : 488
      } ]
    }, {
      "id" : 19361,
      "points" : [ {
        "x" : 982,
        "y" : 486
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 19362,
      "points" : [ {
        "x" : 919,
        "y" : 593
      } ]
    }, {
      "id" : 19363,
      "points" : [ {
        "x" : 994,
        "y" : 594
      } ],
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 19361,
      "points" : [ {
        "x" : 990,
        "y" : 486
      } ]
    } ]
  }, {
    "id" : 19327,
    "reactomeId" : 10608573,
    "displayName" : "PIAS1 SUMOylates SAFB with SUMO2,3",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 672,
      "y" : 316
    },
    "minX" : 666,
    "maxX" : 695,
    "minY" : 292,
    "maxY" : 344,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 695,
        "y" : 292
      },
      "to" : {
        "x" : 672,
        "y" : 316
      }
    }, {
      "from" : {
        "x" : 672,
        "y" : 316
      },
      "to" : {
        "x" : 672,
        "y" : 344
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 666,
        "y" : 310
      },
      "b" : {
        "x" : 678,
        "y" : 322
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 672,
        "y" : 316
      }
    },
    "inputs" : [ {
      "id" : 19323,
      "points" : [ {
        "x" : 650,
        "y" : 264
      } ]
    }, {
      "id" : 19328,
      "points" : [ {
        "x" : 738,
        "y" : 269
      } ],
      "stoichiometry" : 4
    } ],
    "outputs" : [ {
      "id" : 19329,
      "points" : [ {
        "x" : 698,
        "y" : 353
      } ]
    }, {
      "id" : 19326,
      "points" : [ {
        "x" : 650,
        "y" : 355
      } ],
      "stoichiometry" : 4
    } ],
    "catalysts" : [ {
      "id" : 19321,
      "points" : [ {
        "x" : 470,
        "y" : 311
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 19384,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 710,
      "y" : 548
    },
    "minX" : 0,
    "maxX" : 1420,
    "minY" : 0,
    "maxY" : 1096,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 1420,
      "height" : 1096
    },
    "textPosition" : {
      "x" : 13,
      "y" : 1049
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 1400,
      "height" : 1076
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 19298, 19299, 19300, 19303, 19304, 19305, 19306, 19307, 19310, 19311, 19312, 19313, 19314, 19315, 19317, 19318, 19319, 19320, 19321, 19322, 19323, 19327, 19329, 19328, 19324, 19326, 19330, 19331, 19332, 19334, 19335, 19336, 19337, 19339, 19345, 19346, 19350, 19347, 19349, 19351, 19352, 19354, 19355, 19356, 19358, 19364, 19365, 19369, 19371, 19366, 19368, 19370, 19372, 19373, 19375, 19377, 19374, 19376, 19378, 19379, 19383, 19380, 19382, 19340, 19341, 19342, 19344, 19359, 19360, 19361, 19363, 19302, 19308, 19316, 19325, 19333, 19338, 19343, 19348, 19353, 19357, 19362, 19367, 19381, 19309, 19301 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 1420,
  "minY" : 0,
  "maxY" : 1096,
  "disease" : false
}