{ "dbId" : 10647690, "stableId" : "R-DRE-2187338", "displayName" : "Visual phototransduction", "nodes" : [ { "id" : 128265, "reactomeId" : 10604001, "displayName" : "stra6", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 218, "y" : 761 }, "minX" : 195, "maxX" : 275, "minY" : 744, "maxY" : 796, "prop" : { "x" : 195, "y" : 750, "width" : 47, "height" : 22 }, "textPosition" : { "x" : 198, "y" : 750 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 242, "y" : 750 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 242, "y" : 750 } } }, "connectors" : [ { "edgeId" : 128263, "type" : "INPUT", "segments" : [ { "from" : { "x" : 235, "y" : 775 }, "to" : { "x" : 275, "y" : 796 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128264, "reactomeId" : 10603844, "displayName" : "TTR:RBP4:atROL", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 222, "y" : 862 }, "minX" : 169, "maxX" : 282, "minY" : 796, "maxY" : 873, "prop" : { "x" : 169, "y" : 851, "width" : 107, "height" : 22 }, "textPosition" : { "x" : 169, "y" : 852 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 276, "y" : 851 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 276, "y" : 851 } } }, "connectors" : [ { "edgeId" : 128263, "type" : "INPUT", "segments" : [ { "from" : { "x" : 230, "y" : 848 }, "to" : { "x" : 275, "y" : 796 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128266, "reactomeId" : 10604003, "displayName" : "TTR:RBP4:atROL:STRA6", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 381, "y" : 796 }, "minX" : 327, "maxX" : 442, "minY" : 772, "maxY" : 814, "prop" : { "x" : 327, "y" : 778, "width" : 109, "height" : 36 }, "textPosition" : { "x" : 338, "y" : 779 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 436, "y" : 778 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 436, "y" : 778 } } }, "connectors" : [ { "edgeId" : 128263, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128267, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128269, "reactomeId" : 2473604, "displayName" : "atROL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 500, "y" : 729 }, "minX" : 397, "maxX" : 527, "minY" : 713, "maxY" : 796, "prop" : { "x" : 475, "y" : 714, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 478, "y" : 718 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 521, "y" : 719 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 521, "y" : 719 } } }, "connectors" : [ { "edgeId" : 128267, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 499, "y" : 747 }, "to" : { "x" : 499, "y" : 796 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 503, "y" : 754 }, "b" : { "x" : 499, "y" : 747 }, "c" : { "x" : 495, "y" : 754 }, "type" : "ARROW", "centre" : { "x" : 495, "y" : 754 } } }, { "edgeId" : 128270, "type" : "INPUT", "segments" : [ { "from" : { "x" : 472, "y" : 729 }, "to" : { "x" : 397, "y" : 729 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128268, "reactomeId" : 10604005, "displayName" : "TTR:RBP4:STRA6", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 582, "y" : 796 }, "minX" : 499, "maxX" : 643, "minY" : 779, "maxY" : 807, "prop" : { "x" : 528, "y" : 785, "width" : 109, "height" : 22 }, "textPosition" : { "x" : 528, "y" : 786 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 637, "y" : 785 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 637, "y" : 785 } } }, "connectors" : [ { "edgeId" : 128267, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 525, "y" : 796 }, "to" : { "x" : 499, "y" : 796 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 518, "y" : 800 }, "b" : { "x" : 525, "y" : 796 }, "c" : { "x" : 518, "y" : 792 }, "type" : "ARROW", "centre" : { "x" : 518, "y" : 792 } } } ] }, { "id" : 128271, "reactomeId" : 10564217, "displayName" : "rbp1.1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 430, "y" : 693 }, "minX" : 397, "maxX" : 457, "minY" : 676, "maxY" : 729, "prop" : { "x" : 410, "y" : 682, "width" : 41, "height" : 22 }, "textPosition" : { "x" : 410, "y" : 676 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 451, "y" : 682 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 451, "y" : 682 } } }, "connectors" : [ { "edgeId" : 128270, "type" : "INPUT", "segments" : [ { "from" : { "x" : 419, "y" : 707 }, "to" : { "x" : 397, "y" : 729 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128272, "reactomeId" : 10564219, "displayName" : "RBP1:atROL", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 320, "y" : 729 }, "minX" : 280, "maxX" : 367, "minY" : 617, "maxY" : 740, "prop" : { "x" : 280, "y" : 718, "width" : 81, "height" : 22 }, "textPosition" : { "x" : 280, "y" : 719 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 361, "y" : 718 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 361, "y" : 718 } } }, "connectors" : [ { "edgeId" : 128270, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128273, "type" : "INPUT", "segments" : [ { "from" : { "x" : 319, "y" : 715 }, "to" : { "x" : 318, "y" : 617 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128275, "reactomeId" : 9982476, "displayName" : "atRE", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 282, "y" : 383 }, "minX" : 261, "maxX" : 305, "minY" : 335, "maxY" : 464, "prop" : { "x" : 261, "y" : 368, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 264, "y" : 373 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 299, "y" : 373 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 299, "y" : 373 } } }, "connectors" : [ { "edgeId" : 128273, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 285, "y" : 402 }, "to" : { "x" : 302, "y" : 464 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 291, "y" : 408 }, "b" : { "x" : 285, "y" : 402 }, "c" : { "x" : 283, "y" : 410 }, "type" : "ARROW", "centre" : { "x" : 283, "y" : 410 } } }, { "edgeId" : 128278, "type" : "INPUT", "segments" : [ { "from" : { "x" : 283, "y" : 365 }, "to" : { "x" : 288, "y" : 335 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128274, "reactomeId" : 9982900, "displayName" : "RCOO-", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 223, "y" : 607 }, "minX" : 194, "maxX" : 318, "minY" : 591, "maxY" : 623, "prop" : { "x" : 194, "y" : 592, "width" : 58, "height" : 31 }, "textPosition" : { "x" : 200, "y" : 597 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 247, "y" : 597 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 247, "y" : 597 } } }, "connectors" : [ { "edgeId" : 128273, "type" : "INPUT", "segments" : [ { "from" : { "x" : 255, "y" : 610 }, "to" : { "x" : 318, "y" : 617 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128277, "reactomeId" : 10590788, "displayName" : "LOC137487234", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 389, "y" : 504 }, "minX" : 324, "maxX" : 415, "minY" : 487, "maxY" : 525, "prop" : { "x" : 370, "y" : 493, "width" : 39, "height" : 22 }, "textPosition" : { "x" : 370, "y" : 473 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 409, "y" : 493 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 409, "y" : 493 } } }, "connectors" : [ { "edgeId" : 128273, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 367, "y" : 509 }, "to" : { "x" : 332, "y" : 519 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 328, "y" : 521 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 328, "y" : 521 } } } ] }, { "id" : 128276, "reactomeId" : 10564217, "displayName" : "rbp1.1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 247, "y" : 492 }, "minX" : 227, "maxX" : 302, "minY" : 464, "maxY" : 503, "prop" : { "x" : 227, "y" : 481, "width" : 41, "height" : 22 }, "textPosition" : { "x" : 227, "y" : 475 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 268, "y" : 481 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 268, "y" : 481 } } }, "connectors" : [ { "edgeId" : 128273, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 271, "y" : 481 }, "to" : { "x" : 302, "y" : 464 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 275, "y" : 474 }, "b" : { "x" : 271, "y" : 481 }, "c" : { "x" : 279, "y" : 481 }, "type" : "ARROW", "centre" : { "x" : 279, "y" : 481 } } } ] }, { "id" : 128279, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 412, "y" : 359 }, "minX" : 288, "maxX" : 435, "minY" : 335, "maxY" : 375, "prop" : { "x" : 391, "y" : 344, "width" : 43, "height" : 31 }, "textPosition" : { "x" : 395, "y" : 349 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 429, "y" : 349 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 429, "y" : 349 } } }, "connectors" : [ { "edgeId" : 128278, "type" : "INPUT", "segments" : [ { "from" : { "x" : 388, "y" : 354 }, "to" : { "x" : 288, "y" : 335 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 128281, "reactomeId" : 9982478, "displayName" : "RCOO-", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 335, "y" : 321 }, "minX" : 302, "maxX" : 365, "minY" : 239, "maxY" : 337, "prop" : { "x" : 306, "y" : 306, "width" : 58, "height" : 31 }, "textPosition" : { "x" : 312, "y" : 311 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 359, "y" : 311 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 359, "y" : 311 } } }, "connectors" : [ { "edgeId" : 128278, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 328, "y" : 303 }, "to" : { "x" : 302, "y" : 239 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 322, "y" : 298 }, "b" : { "x" : 328, "y" : 303 }, "c" : { "x" : 329, "y" : 295 }, "type" : "ARROW", "centre" : { "x" : 329, "y" : 295 } } } ] }, { "id" : 128280, "reactomeId" : 30927, "displayName" : "11cROL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 327, "y" : 177 }, "minX" : 296, "maxX" : 401, "minY" : 161, "maxY" : 239, "prop" : { "x" : 296, "y" : 162, "width" : 62, "height" : 30 }, "textPosition" : { "x" : 300, "y" : 166 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 353, "y" : 167 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 353, "y" : 167 } } }, "connectors" : [ { "edgeId" : 128278, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 320, "y" : 195 }, "to" : { "x" : 302, "y" : 239 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 321, "y" : 203 }, "b" : { "x" : 320, "y" : 195 }, "c" : { "x" : 314, "y" : 200 }, "type" : "ARROW", "centre" : { "x" : 314, "y" : 200 } } }, { "edgeId" : 128284, "type" : "INPUT", "segments" : [ { "from" : { "x" : 361, "y" : 170 }, "to" : { "x" : 401, "y" : 161 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128283, "reactomeId" : 10603992, "displayName" : "RPE65", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 212, "y" : 279 }, "minX" : 188, "maxX" : 279, "minY" : 260, "maxY" : 292, "prop" : { "x" : 188, "y" : 266, "width" : 49, "height" : 26 }, "textPosition" : { "x" : 188, "y" : 268 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 237, "y" : 266 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 237, "y" : 266 } } }, "connectors" : [ { "edgeId" : 128278, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 240, "y" : 278 }, "to" : { "x" : 271, "y" : 278 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 275, "y" : 278 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 275, "y" : 278 } } } ] }, { "id" : 128282, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 351, "y" : 222 }, "minX" : 302, "maxX" : 370, "minY" : 206, "maxY" : 239, "prop" : { "x" : 333, "y" : 207, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 337, "y" : 211 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 364, "y" : 212 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 364, "y" : 212 } } }, "connectors" : [ { "edgeId" : 128278, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 330, "y" : 228 }, "to" : { "x" : 302, "y" : 239 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 325, "y" : 234 }, "b" : { "x" : 330, "y" : 228 }, "c" : { "x" : 322, "y" : 227 }, "type" : "ARROW", "centre" : { "x" : 322, "y" : 227 } } } ], "trivial" : true }, { "id" : 128285, "reactomeId" : 10564225, "displayName" : "rlbp1b", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 353, "y" : 122 }, "minX" : 330, "maxX" : 836, "minY" : 65, "maxY" : 196, "prop" : { "x" : 330, "y" : 111, "width" : 47, "height" : 22 }, "textPosition" : { "x" : 333, "y" : 105 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 377, "y" : 111 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 377, "y" : 111 } } }, "connectors" : [ { "edgeId" : 128408, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 352, "y" : 108 }, "to" : { "x" : 352, "y" : 65 } }, { "from" : { "x" : 352, "y" : 65 }, "to" : { "x" : 806, "y" : 65 } }, { "from" : { "x" : 806, "y" : 65 }, "to" : { "x" : 836, "y" : 196 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 348, "y" : 101 }, "b" : { "x" : 352, "y" : 108 }, "c" : { "x" : 356, "y" : 101 }, "type" : "ARROW", "centre" : { "x" : 356, "y" : 101 } } }, { "edgeId" : 128284, "type" : "INPUT", "segments" : [ { "from" : { "x" : 366, "y" : 136 }, "to" : { "x" : 401, "y" : 161 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128286, "reactomeId" : 10564227, "displayName" : "RLBP1:11cROL", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 486, "y" : 162 }, "minX" : 438, "maxX" : 575, "minY" : 145, "maxY" : 343, "prop" : { "x" : 438, "y" : 151, "width" : 97, "height" : 22 }, "textPosition" : { "x" : 438, "y" : 152 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 535, "y" : 151 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 535, "y" : 151 } } }, "connectors" : [ { "edgeId" : 128284, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128287, "type" : "INPUT", "segments" : [ { "from" : { "x" : 538, "y" : 159 }, "to" : { "x" : 575, "y" : 158 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128293, "type" : "INPUT", "segments" : [ { "from" : { "x" : 487, "y" : 176 }, "to" : { "x" : 516, "y" : 343 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128289, "reactomeId" : 10564229, "displayName" : "RLBP1:11cRAL", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 764, "y" : 158 }, "minX" : 639, "maxX" : 818, "minY" : 141, "maxY" : 343, "prop" : { "x" : 716, "y" : 147, "width" : 96, "height" : 22 }, "textPosition" : { "x" : 716, "y" : 148 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 812, "y" : 147 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 812, "y" : 147 } } }, "connectors" : [ { "edgeId" : 128408, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128287, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 713, "y" : 158 }, "to" : { "x" : 639, "y" : 158 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 706, "y" : 162 }, "b" : { "x" : 713, "y" : 158 }, "c" : { "x" : 706, "y" : 154 }, "type" : "ARROW", "centre" : { "x" : 706, "y" : 154 } } }, { "edgeId" : 128293, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 761, "y" : 172 }, "to" : { "x" : 735, "y" : 296 } }, { "from" : { "x" : 735, "y" : 296 }, "to" : { "x" : 685, "y" : 343 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 763, "y" : 180 }, "b" : { "x" : 761, "y" : 172 }, "c" : { "x" : 756, "y" : 178 }, "type" : "ARROW", "centre" : { "x" : 756, "y" : 178 } } } ] }, { "id" : 128288, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 537, "y" : 125 }, "minX" : 507, "maxX" : 575, "minY" : 109, "maxY" : 158, "prop" : { "x" : 507, "y" : 110, "width" : 60, "height" : 30 }, "textPosition" : { "x" : 511, "y" : 114 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 562, "y" : 115 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 562, "y" : 115 } } }, "connectors" : [ { "edgeId" : 128287, "type" : "INPUT", "segments" : [ { "from" : { "x" : 554, "y" : 143 }, "to" : { "x" : 575, "y" : 158 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128291, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 705, "y" : 127 }, "minX" : 639, "maxX" : 736, "minY" : 111, "maxY" : 158, "prop" : { "x" : 676, "y" : 112, "width" : 59, "height" : 30 }, "textPosition" : { "x" : 680, "y" : 116 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 730, "y" : 117 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 730, "y" : 117 } } }, "connectors" : [ { "edgeId" : 128287, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 673, "y" : 140 }, "to" : { "x" : 639, "y" : 158 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 669, "y" : 147 }, "b" : { "x" : 673, "y" : 140 }, "c" : { "x" : 665, "y" : 140 }, "type" : "ARROW", "centre" : { "x" : 665, "y" : 140 } } } ] }, { "id" : 128290, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 652, "y" : 119 }, "minX" : 634, "maxX" : 671, "minY" : 103, "maxY" : 158, "prop" : { "x" : 634, "y" : 104, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 638, "y" : 108 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 665, "y" : 109 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 665, "y" : 109 } } }, "connectors" : [ { "edgeId" : 128287, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 647, "y" : 137 }, "to" : { "x" : 639, "y" : 158 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 648, "y" : 145 }, "b" : { "x" : 647, "y" : 137 }, "c" : { "x" : 641, "y" : 142 }, "type" : "ARROW", "centre" : { "x" : 641, "y" : 142 } } } ], "trivial" : true }, { "id" : 128292, "reactomeId" : 10564239, "displayName" : "RDH10,11", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 606, "y" : 197 }, "minX" : 571, "maxX" : 642, "minY" : 166, "maxY" : 208, "prop" : { "x" : 571, "y" : 186, "width" : 71, "height" : 22 }, "textPosition" : { "x" : 571, "y" : 186 }, "connectors" : [ { "edgeId" : 128287, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 605, "y" : 180 }, "to" : { "x" : 605, "y" : 174 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 605, "y" : 170 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 605, "y" : 170 } } } ] }, { "id" : 128295, "reactomeId" : 73473, "displayName" : "NADH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 692, "y" : 388 }, "minX" : 666, "maxX" : 719, "minY" : 343, "maxY" : 403, "prop" : { "x" : 666, "y" : 373, "width" : 52, "height" : 30 }, "textPosition" : { "x" : 670, "y" : 377 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 713, "y" : 378 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 713, "y" : 378 } } }, "connectors" : [ { "edgeId" : 128293, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 689, "y" : 370 }, "to" : { "x" : 685, "y" : 343 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 684, "y" : 364 }, "b" : { "x" : 689, "y" : 370 }, "c" : { "x" : 692, "y" : 363 }, "type" : "ARROW", "centre" : { "x" : 692, "y" : 363 } } } ] }, { "id" : 128294, "reactomeId" : 29360, "displayName" : "NAD+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 478, "y" : 372 }, "minX" : 452, "maxX" : 516, "minY" : 343, "maxY" : 387, "prop" : { "x" : 452, "y" : 357, "width" : 53, "height" : 30 }, "textPosition" : { "x" : 456, "y" : 361 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 500, "y" : 362 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 500, "y" : 362 } } }, "connectors" : [ { "edgeId" : 128293, "type" : "INPUT", "segments" : [ { "from" : { "x" : 497, "y" : 354 }, "to" : { "x" : 516, "y" : 343 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128297, "reactomeId" : 10604025, "displayName" : "RDH5(1-318)-like Proteins", "schemaClass" : "CandidateSet", "renderableClass" : "EntitySet", "position" : { "x" : 612, "y" : 296 }, "minX" : 552, "maxX" : 673, "minY" : 278, "maxY" : 335, "prop" : { "x" : 552, "y" : 278, "width" : 121, "height" : 36 }, "textPosition" : { "x" : 554, "y" : 278 }, "connectors" : [ { "edgeId" : 128293, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 612, "y" : 320 }, "to" : { "x" : 612, "y" : 327 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 612, "y" : 331 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 612, "y" : 331 } } } ] }, { "id" : 128296, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 730, "y" : 356 }, "minX" : 685, "maxX" : 749, "minY" : 340, "maxY" : 371, "prop" : { "x" : 712, "y" : 341, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 716, "y" : 345 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 743, "y" : 346 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 743, "y" : 346 } } }, "connectors" : [ { "edgeId" : 128293, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 709, "y" : 350 }, "to" : { "x" : 685, "y" : 343 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 701, "y" : 352 }, "b" : { "x" : 709, "y" : 350 }, "c" : { "x" : 703, "y" : 344 }, "type" : "ARROW", "centre" : { "x" : 703, "y" : 344 } } } ], "trivial" : true }, { "id" : 128299, "reactomeId" : 10564289, "displayName" : "rho", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1092, "y" : 286 }, "minX" : 1075, "maxX" : 1127, "minY" : 269, "maxY" : 297, "prop" : { "x" : 1075, "y" : 275, "width" : 35, "height" : 22 }, "textPosition" : { "x" : 1078, "y" : 275 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1110, "y" : 275 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1110, "y" : 275 } } }, "connectors" : [ { "edgeId" : 128298, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1113, "y" : 285 }, "to" : { "x" : 1127, "y" : 285 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128301, "reactomeId" : 10563839, "displayName" : "rho", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1238, "y" : 288 }, "minX" : 1163, "maxX" : 1304, "minY" : 271, "maxY" : 299, "prop" : { "x" : 1185, "y" : 277, "width" : 106, "height" : 22 }, "textPosition" : { "x" : 1223, "y" : 277 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1291, "y" : 277 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1291, "y" : 277 } } }, "connectors" : [ { "edgeId" : 128416, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1294, "y" : 286 }, "to" : { "x" : 1304, "y" : 286 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128298, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1182, "y" : 285 }, "to" : { "x" : 1163, "y" : 285 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1175, "y" : 289 }, "b" : { "x" : 1182, "y" : 285 }, "c" : { "x" : 1175, "y" : 281 }, "type" : "ARROW", "centre" : { "x" : 1175, "y" : 281 } } } ] }, { "id" : 128300, "reactomeId" : 32737, "displayName" : "11cRAL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1088, "y" : 214 }, "minX" : 1058, "maxX" : 1127, "minY" : 198, "maxY" : 285, "prop" : { "x" : 1058, "y" : 199, "width" : 61, "height" : 30 }, "textPosition" : { "x" : 1062, "y" : 203 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1114, "y" : 204 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1114, "y" : 204 } } }, "connectors" : [ { "edgeId" : 128298, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1096, "y" : 232 }, "to" : { "x" : 1127, "y" : 285 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128302, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1205, "y" : 333 }, "minX" : 1163, "maxX" : 1228, "minY" : 285, "maxY" : 348, "prop" : { "x" : 1184, "y" : 318, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 1188, "y" : 322 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1222, "y" : 323 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1222, "y" : 323 } } }, "connectors" : [ { "edgeId" : 128298, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1191, "y" : 315 }, "to" : { "x" : 1163, "y" : 285 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1183, "y" : 313 }, "b" : { "x" : 1191, "y" : 315 }, "c" : { "x" : 1189, "y" : 307 }, "type" : "ARROW", "centre" : { "x" : 1189, "y" : 307 } } } ], "trivial" : true }, { "id" : 128305, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1716, "y" : 459 }, "minX" : 1674, "maxX" : 1737, "minY" : 443, "maxY" : 474, "prop" : { "x" : 1696, "y" : 444, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 1700, "y" : 448 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1731, "y" : 449 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1731, "y" : 449 } } }, "connectors" : [ { "edgeId" : 128303, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1693, "y" : 462 }, "to" : { "x" : 1674, "y" : 467 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128304, "reactomeId" : 2466098, "displayName" : "atRAL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1713, "y" : 403 }, "minX" : 1674, "maxX" : 2251, "minY" : 387, "maxY" : 510, "prop" : { "x" : 1688, "y" : 388, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 1691, "y" : 392 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1733, "y" : 393 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1733, "y" : 393 } } }, "connectors" : [ { "edgeId" : 128303, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1703, "y" : 421 }, "to" : { "x" : 1674, "y" : 467 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128380, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1731, "y" : 421 }, "to" : { "x" : 1843, "y" : 506 } }, { "from" : { "x" : 1843, "y" : 506 }, "to" : { "x" : 2232, "y" : 510 } }, { "from" : { "x" : 2232, "y" : 510 }, "to" : { "x" : 2251, "y" : 397 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1739, "y" : 422 }, "b" : { "x" : 1731, "y" : 421 }, "c" : { "x" : 1734, "y" : 428 }, "type" : "ARROW", "centre" : { "x" : 1734, "y" : 428 } } } ] }, { "id" : 128307, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1643, "y" : 561 }, "minX" : 1623, "maxX" : 1668, "minY" : 522, "maxY" : 576, "prop" : { "x" : 1623, "y" : 546, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 1627, "y" : 550 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1659, "y" : 551 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1659, "y" : 551 } } }, "connectors" : [ { "edgeId" : 128303, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1652, "y" : 543 }, "to" : { "x" : 1668, "y" : 522 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1653, "y" : 535 }, "b" : { "x" : 1652, "y" : 543 }, "c" : { "x" : 1659, "y" : 540 }, "type" : "ARROW", "centre" : { "x" : 1659, "y" : 540 } } } ] }, { "id" : 128306, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1719, "y" : 496 }, "minX" : 1674, "maxX" : 1742, "minY" : 467, "maxY" : 511, "prop" : { "x" : 1698, "y" : 481, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 1702, "y" : 485 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1736, "y" : 486 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1736, "y" : 486 } } }, "connectors" : [ { "edgeId" : 128303, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1695, "y" : 482 }, "to" : { "x" : 1674, "y" : 467 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 128309, "reactomeId" : 975622, "displayName" : "atRAL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1775, "y" : 582 }, "minX" : 1668, "maxX" : 1888, "minY" : 522, "maxY" : 635, "prop" : { "x" : 1750, "y" : 567, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 1753, "y" : 571 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1795, "y" : 572 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1795, "y" : 572 } } }, "connectors" : [ { "edgeId" : 128303, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1747, "y" : 567 }, "to" : { "x" : 1668, "y" : 522 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1739, "y" : 567 }, "b" : { "x" : 1747, "y" : 567 }, "c" : { "x" : 1743, "y" : 560 }, "type" : "ARROW", "centre" : { "x" : 1743, "y" : 560 } } }, { "edgeId" : 128311, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1803, "y" : 593 }, "to" : { "x" : 1888, "y" : 635 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128308, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1690, "y" : 572 }, "minX" : 1668, "maxX" : 1705, "minY" : 522, "maxY" : 587, "prop" : { "x" : 1677, "y" : 557, "width" : 27, "height" : 30 }, "textPosition" : { "x" : 1681, "y" : 561 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1699, "y" : 562 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1699, "y" : 562 } } }, "connectors" : [ { "edgeId" : 128303, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1683, "y" : 554 }, "to" : { "x" : 1668, "y" : 522 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1676, "y" : 549 }, "b" : { "x" : 1683, "y" : 554 }, "c" : { "x" : 1684, "y" : 546 }, "type" : "ARROW", "centre" : { "x" : 1684, "y" : 546 } } } ] }, { "id" : 128310, "reactomeId" : 10595634, "displayName" : "abca4b", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1648, "y" : 401 }, "minX" : 1624, "maxX" : 1678, "minY" : 384, "maxY" : 459, "prop" : { "x" : 1624, "y" : 390, "width" : 48, "height" : 22 }, "textPosition" : { "x" : 1624, "y" : 384 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1672, "y" : 390 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1672, "y" : 390 } } }, "connectors" : [ { "edgeId" : 128303, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1648, "y" : 415 }, "to" : { "x" : 1648, "y" : 451 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1648, "y" : 455 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1648, "y" : 455 } } } ] }, { "id" : 128313, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1839, "y" : 665 }, "minX" : 1810, "maxX" : 1888, "minY" : 635, "maxY" : 680, "prop" : { "x" : 1810, "y" : 650, "width" : 59, "height" : 30 }, "textPosition" : { "x" : 1814, "y" : 654 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1864, "y" : 655 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1864, "y" : 655 } } }, "connectors" : [ { "edgeId" : 128311, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1863, "y" : 647 }, "to" : { "x" : 1888, "y" : 635 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128312, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1864, "y" : 710 }, "minX" : 1846, "maxX" : 1888, "minY" : 635, "maxY" : 725, "prop" : { "x" : 1846, "y" : 695, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 1850, "y" : 699 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1877, "y" : 700 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1877, "y" : 700 } } }, "connectors" : [ { "edgeId" : 128311, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1868, "y" : 692 }, "to" : { "x" : 1888, "y" : 635 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 128315, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1868, "y" : 760 }, "minX" : 1838, "maxX" : 1918, "minY" : 739, "maxY" : 775, "prop" : { "x" : 1838, "y" : 745, "width" : 60, "height" : 30 }, "textPosition" : { "x" : 1842, "y" : 749 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1893, "y" : 750 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1893, "y" : 750 } } }, "connectors" : [ { "edgeId" : 128311, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1901, "y" : 747 }, "to" : { "x" : 1918, "y" : 739 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1906, "y" : 740 }, "b" : { "x" : 1901, "y" : 747 }, "c" : { "x" : 1909, "y" : 748 }, "type" : "ARROW", "centre" : { "x" : 1909, "y" : 748 } } } ] }, { "id" : 128314, "reactomeId" : 2473615, "displayName" : "atROL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1878, "y" : 804 }, "minX" : 1853, "maxX" : 1918, "minY" : 739, "maxY" : 819, "prop" : { "x" : 1853, "y" : 789, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 1856, "y" : 793 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1899, "y" : 794 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1899, "y" : 794 } } }, "connectors" : [ { "edgeId" : 128311, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1887, "y" : 786 }, "to" : { "x" : 1918, "y" : 739 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1887, "y" : 778 }, "b" : { "x" : 1887, "y" : 786 }, "c" : { "x" : 1894, "y" : 782 }, "type" : "ARROW", "centre" : { "x" : 1894, "y" : 782 } } } ] }, { "id" : 128316, "reactomeId" : 10604040, "displayName" : "Homologues of RDH12", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 2192, "y" : 836 }, "minX" : 1915, "maxX" : 2218, "minY" : 703, "maxY" : 847, "prop" : { "x" : 2167, "y" : 825, "width" : 51, "height" : 22 }, "textPosition" : { "x" : 2167, "y" : 805 }, "connectors" : [ { "edgeId" : 128311, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 2168, "y" : 822 }, "to" : { "x" : 1923, "y" : 709 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1919, "y" : 707 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1919, "y" : 707 } } } ] }, { "id" : 128319, "reactomeId" : 10564225, "displayName" : "rlbp1b", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 778, "y" : 1070 }, "minX" : 755, "maxX" : 808, "minY" : 1025, "maxY" : 1081, "prop" : { "x" : 755, "y" : 1059, "width" : 47, "height" : 22 }, "textPosition" : { "x" : 758, "y" : 1053 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 802, "y" : 1059 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 802, "y" : 1059 } } }, "connectors" : [ { "edgeId" : 128317, "type" : "INPUT", "segments" : [ { "from" : { "x" : 773, "y" : 1056 }, "to" : { "x" : 759, "y" : 1025 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128318, "reactomeId" : 2473617, "displayName" : "atROL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 814, "y" : 1026 }, "minX" : 759, "maxX" : 841, "minY" : 1010, "maxY" : 1041, "prop" : { "x" : 789, "y" : 1011, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 792, "y" : 1015 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 835, "y" : 1016 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 835, "y" : 1016 } } }, "connectors" : [ { "edgeId" : 128317, "type" : "INPUT", "segments" : [ { "from" : { "x" : 786, "y" : 1025 }, "to" : { "x" : 759, "y" : 1025 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128320, "reactomeId" : 10604101, "displayName" : "RLBP1:atROL", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 656, "y" : 1027 }, "minX" : 613, "maxX" : 706, "minY" : 1010, "maxY" : 1038, "prop" : { "x" : 613, "y" : 1016, "width" : 87, "height" : 22 }, "textPosition" : { "x" : 613, "y" : 1017 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 700, "y" : 1016 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 700, "y" : 1016 } } }, "connectors" : [ { "edgeId" : 128317, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128323, "reactomeId" : 10564227, "displayName" : "RLBP1:11cROL", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 384, "y" : 1025 }, "minX" : 336, "maxX" : 439, "minY" : 1008, "maxY" : 1066, "prop" : { "x" : 336, "y" : 1014, "width" : 97, "height" : 22 }, "textPosition" : { "x" : 336, "y" : 1015 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 433, "y" : 1014 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 433, "y" : 1014 } } }, "connectors" : [ { "edgeId" : 128321, "type" : "INPUT", "segments" : [ { "from" : { "x" : 383, "y" : 1039 }, "to" : { "x" : 383, "y" : 1066 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128322, "reactomeId" : 200993, "displayName" : "PALM-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 312, "y" : 1059 }, "minX" : 273, "maxX" : 383, "minY" : 1043, "maxY" : 1074, "prop" : { "x" : 273, "y" : 1044, "width" : 78, "height" : 30 }, "textPosition" : { "x" : 278, "y" : 1048 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 346, "y" : 1049 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 346, "y" : 1049 } } }, "connectors" : [ { "edgeId" : 128321, "type" : "INPUT", "segments" : [ { "from" : { "x" : 354, "y" : 1062 }, "to" : { "x" : 383, "y" : 1066 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128325, "reactomeId" : 10604083, "displayName" : "RLBP1:11cRPALM", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 384, "y" : 1181 }, "minX" : 329, "maxX" : 445, "minY" : 1129, "maxY" : 1192, "prop" : { "x" : 329, "y" : 1170, "width" : 110, "height" : 22 }, "textPosition" : { "x" : 348, "y" : 1157 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 439, "y" : 1170 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 439, "y" : 1170 } } }, "connectors" : [ { "edgeId" : 128321, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 383, "y" : 1167 }, "to" : { "x" : 383, "y" : 1129 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 379, "y" : 1160 }, "b" : { "x" : 383, "y" : 1167 }, "c" : { "x" : 387, "y" : 1160 }, "type" : "ARROW", "centre" : { "x" : 387, "y" : 1160 } } } ] }, { "id" : 128324, "reactomeId" : 76194, "displayName" : "CoA-SH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 325, "y" : 1139 }, "minX" : 294, "maxX" : 383, "minY" : 1123, "maxY" : 1154, "prop" : { "x" : 294, "y" : 1124, "width" : 62, "height" : 30 }, "textPosition" : { "x" : 298, "y" : 1128 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 351, "y" : 1129 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 351, "y" : 1129 } } }, "connectors" : [ { "edgeId" : 128321, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 359, "y" : 1133 }, "to" : { "x" : 383, "y" : 1129 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 365, "y" : 1128 }, "b" : { "x" : 359, "y" : 1133 }, "c" : { "x" : 366, "y" : 1136 }, "type" : "ARROW", "centre" : { "x" : 366, "y" : 1136 } } } ] }, { "id" : 128326, "reactomeId" : 10604087, "displayName" : "mogat3b", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 447, "y" : 1095 }, "minX" : 391, "maxX" : 479, "minY" : 1078, "maxY" : 1106, "prop" : { "x" : 422, "y" : 1084, "width" : 51, "height" : 22 }, "textPosition" : { "x" : 423, "y" : 1078 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 473, "y" : 1084 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 473, "y" : 1084 } } }, "connectors" : [ { "edgeId" : 128321, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 419, "y" : 1095 }, "to" : { "x" : 399, "y" : 1095 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 395, "y" : 1095 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 395, "y" : 1095 } } } ] }, { "id" : 128329, "reactomeId" : 32737, "displayName" : "11cRAL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1272, "y" : 1263 }, "minX" : 1242, "maxX" : 1445, "minY" : 1247, "maxY" : 1287, "prop" : { "x" : 1242, "y" : 1248, "width" : 61, "height" : 30 }, "textPosition" : { "x" : 1246, "y" : 1252 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1298, "y" : 1253 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1298, "y" : 1253 } } }, "connectors" : [ { "edgeId" : 128327, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1306, "y" : 1263 }, "to" : { "x" : 1397, "y" : 1263 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128410, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1306, "y" : 1267 }, "to" : { "x" : 1445, "y" : 1287 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128413, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1306, "y" : 1259 }, "to" : { "x" : 1385, "y" : 1249 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128328, "reactomeId" : 10584257, "displayName" : "Homologues of OPN1LW", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1417, "y" : 1208 }, "minX" : 1388, "maxX" : 1446, "minY" : 1197, "maxY" : 1263, "prop" : { "x" : 1388, "y" : 1197, "width" : 58, "height" : 22 }, "textPosition" : { "x" : 1388, "y" : 1177 }, "connectors" : [ { "edgeId" : 128327, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1413, "y" : 1222 }, "to" : { "x" : 1397, "y" : 1263 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128331, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1515, "y" : 1309 }, "minX" : 1479, "maxX" : 1538, "minY" : 1248, "maxY" : 1324, "prop" : { "x" : 1494, "y" : 1294, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 1498, "y" : 1298 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1532, "y" : 1299 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1532, "y" : 1299 } } }, "connectors" : [ { "edgeId" : 128327, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1508, "y" : 1291 }, "to" : { "x" : 1496, "y" : 1263 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1502, "y" : 1286 }, "b" : { "x" : 1508, "y" : 1291 }, "c" : { "x" : 1509, "y" : 1283 }, "type" : "ARROW", "centre" : { "x" : 1509, "y" : 1283 } } }, { "edgeId" : 128410, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1499, "y" : 1291 }, "to" : { "x" : 1479, "y" : 1275 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1491, "y" : 1290 }, "b" : { "x" : 1499, "y" : 1291 }, "c" : { "x" : 1496, "y" : 1284 }, "type" : "ARROW", "centre" : { "x" : 1496, "y" : 1284 } } }, { "edgeId" : 128413, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1513, "y" : 1291 }, "to" : { "x" : 1510, "y" : 1248 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1509, "y" : 1284 }, "b" : { "x" : 1513, "y" : 1291 }, "c" : { "x" : 1517, "y" : 1284 }, "type" : "ARROW", "centre" : { "x" : 1517, "y" : 1284 } } } ], "trivial" : true }, { "id" : 128330, "reactomeId" : 10604061, "displayName" : "Homologues of 11cRAL-OPN1LW", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1629, "y" : 1256 }, "minX" : 1496, "maxX" : 1684, "minY" : 1245, "maxY" : 1267, "prop" : { "x" : 1575, "y" : 1245, "width" : 109, "height" : 22 }, "textPosition" : { "x" : 1575, "y" : 1239 }, "connectors" : [ { "edgeId" : 128327, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1572, "y" : 1258 }, "to" : { "x" : 1496, "y" : 1263 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1565, "y" : 1262 }, "b" : { "x" : 1572, "y" : 1258 }, "c" : { "x" : 1565, "y" : 1254 }, "type" : "ARROW", "centre" : { "x" : 1565, "y" : 1254 } } } ] }, { "id" : 128333, "reactomeId" : 10604066, "displayName" : "11c-retinyl-cone opsins", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1807, "y" : 1250 }, "minX" : 1752, "maxX" : 1932, "minY" : 1232, "maxY" : 1268, "prop" : { "x" : 1752, "y" : 1232, "width" : 111, "height" : 36 }, "textPosition" : { "x" : 1752, "y" : 1232 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "connectors" : [ { "edgeId" : 128332, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1869, "y" : 1250 }, "to" : { "x" : 1932, "y" : 1250 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128335, "reactomeId" : 10604079, "displayName" : "at-retinyl-cone opsins", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1930, "y" : 1115 }, "minX" : 1696, "maxX" : 1981, "minY" : 1098, "maxY" : 1133, "prop" : { "x" : 1879, "y" : 1098, "width" : 102, "height" : 35 }, "textPosition" : { "x" : 1879, "y" : 1098 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "connectors" : [ { "edgeId" : 128332, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128336, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1873, "y" : 1111 }, "to" : { "x" : 1696, "y" : 1101 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128334, "reactomeId" : 419777, "displayName" : "Photon", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1869, "y" : 1368 }, "minX" : 1842, "maxX" : 1932, "minY" : 1250, "maxY" : 1379, "prop" : { "x" : 1842, "y" : 1357, "width" : 54, "height" : 22 }, "textPosition" : { "x" : 1842, "y" : 1357 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1891, "y" : 1362 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1891, "y" : 1362 } } }, "connectors" : [ { "edgeId" : 128332, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1874, "y" : 1354 }, "to" : { "x" : 1932, "y" : 1250 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128337, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1756, "y" : 1068 }, "minX" : 1696, "maxX" : 1779, "minY" : 1052, "maxY" : 1101, "prop" : { "x" : 1735, "y" : 1053, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 1739, "y" : 1057 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1773, "y" : 1058 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1773, "y" : 1058 } } }, "connectors" : [ { "edgeId" : 128336, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1732, "y" : 1079 }, "to" : { "x" : 1696, "y" : 1101 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 128339, "reactomeId" : 975622, "displayName" : "atRAL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1550, "y" : 1043 }, "minX" : 1467, "maxX" : 1600, "minY" : 1027, "maxY" : 1101, "prop" : { "x" : 1525, "y" : 1028, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 1528, "y" : 1032 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1570, "y" : 1033 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1570, "y" : 1033 } } }, "connectors" : [ { "edgeId" : 128336, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1562, "y" : 1061 }, "to" : { "x" : 1600, "y" : 1101 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1570, "y" : 1063 }, "b" : { "x" : 1562, "y" : 1061 }, "c" : { "x" : 1564, "y" : 1069 }, "type" : "ARROW", "centre" : { "x" : 1564, "y" : 1069 } } }, { "edgeId" : 128340, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1522, "y" : 1042 }, "to" : { "x" : 1467, "y" : 1042 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128338, "reactomeId" : 10604143, "displayName" : "Cone apo-opsins", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1395, "y" : 1140 }, "minX" : 1338, "maxX" : 1600, "minY" : 1101, "maxY" : 1151, "prop" : { "x" : 1338, "y" : 1129, "width" : 114, "height" : 22 }, "textPosition" : { "x" : 1338, "y" : 1129 }, "connectors" : [ { "edgeId" : 128336, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1458, "y" : 1129 }, "to" : { "x" : 1600, "y" : 1101 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1464, "y" : 1124 }, "b" : { "x" : 1458, "y" : 1129 }, "c" : { "x" : 1466, "y" : 1132 }, "type" : "ARROW", "centre" : { "x" : 1466, "y" : 1132 } } } ] }, { "id" : 128341, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1497, "y" : 1070 }, "minX" : 1467, "maxX" : 1528, "minY" : 1042, "maxY" : 1085, "prop" : { "x" : 1468, "y" : 1055, "width" : 59, "height" : 30 }, "textPosition" : { "x" : 1472, "y" : 1059 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1522, "y" : 1060 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1522, "y" : 1060 } } }, "connectors" : [ { "edgeId" : 128340, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1480, "y" : 1052 }, "to" : { "x" : 1467, "y" : 1042 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128343, "reactomeId" : 2473607, "displayName" : "atROL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1295, "y" : 1026 }, "minX" : 1270, "maxX" : 1358, "minY" : 1010, "maxY" : 1042, "prop" : { "x" : 1270, "y" : 1011, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 1273, "y" : 1015 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1316, "y" : 1016 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1316, "y" : 1016 } } }, "connectors" : [ { "edgeId" : 128340, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1324, "y" : 1032 }, "to" : { "x" : 1358, "y" : 1042 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1332, "y" : 1030 }, "b" : { "x" : 1324, "y" : 1032 }, "c" : { "x" : 1330, "y" : 1038 }, "type" : "ARROW", "centre" : { "x" : 1330, "y" : 1038 } } } ] }, { "id" : 128342, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1493, "y" : 1010 }, "minX" : 1467, "maxX" : 1512, "minY" : 994, "maxY" : 1042, "prop" : { "x" : 1475, "y" : 995, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 1479, "y" : 999 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1506, "y" : 1000 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1506, "y" : 1000 } } }, "connectors" : [ { "edgeId" : 128340, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1480, "y" : 1028 }, "to" : { "x" : 1467, "y" : 1042 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 128345, "reactomeId" : 10604096, "displayName" : "dhrs3b", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1429, "y" : 990 }, "minX" : 1404, "maxX" : 1461, "minY" : 973, "maxY" : 1034, "prop" : { "x" : 1404, "y" : 979, "width" : 51, "height" : 22 }, "textPosition" : { "x" : 1407, "y" : 973 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1455, "y" : 979 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1455, "y" : 979 } } }, "connectors" : [ { "edgeId" : 128340, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1429, "y" : 1004 }, "to" : { "x" : 1429, "y" : 1026 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1429, "y" : 1030 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1429, "y" : 1030 } } } ] }, { "id" : 128344, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1332, "y" : 1078 }, "minX" : 1302, "maxX" : 1363, "minY" : 1042, "maxY" : 1093, "prop" : { "x" : 1302, "y" : 1063, "width" : 60, "height" : 30 }, "textPosition" : { "x" : 1306, "y" : 1067 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1357, "y" : 1068 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1357, "y" : 1068 } } }, "connectors" : [ { "edgeId" : 128340, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1342, "y" : 1060 }, "to" : { "x" : 1358, "y" : 1042 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1344, "y" : 1052 }, "b" : { "x" : 1342, "y" : 1060 }, "c" : { "x" : 1350, "y" : 1057 }, "type" : "ARROW", "centre" : { "x" : 1350, "y" : 1057 } } } ] }, { "id" : 128347, "reactomeId" : 10604356, "displayName" : "Gt-GTP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1614, "y" : 285 }, "minX" : 1588, "maxX" : 1647, "minY" : 268, "maxY" : 296, "prop" : { "x" : 1588, "y" : 274, "width" : 53, "height" : 22 }, "textPosition" : { "x" : 1589, "y" : 275 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1641, "y" : 274 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1641, "y" : 274 } } }, "connectors" : [ { "edgeId" : 128346, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128349, "reactomeId" : 10563815, "displayName" : "GNAT1-GTP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1848, "y" : 281 }, "minX" : 1672, "maxX" : 1895, "minY" : 257, "maxY" : 292, "prop" : { "x" : 1807, "y" : 270, "width" : 82, "height" : 22 }, "textPosition" : { "x" : 1809, "y" : 271 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1889, "y" : 270 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1889, "y" : 270 } } }, "connectors" : [ { "edgeId" : 128346, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1804, "y" : 273 }, "to" : { "x" : 1723, "y" : 257 } }, { "from" : { "x" : 1723, "y" : 257 }, "to" : { "x" : 1672, "y" : 273 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1796, "y" : 276 }, "b" : { "x" : 1804, "y" : 273 }, "c" : { "x" : 1798, "y" : 268 }, "type" : "ARROW", "centre" : { "x" : 1798, "y" : 268 } } } ] }, { "id" : 128348, "reactomeId" : 10604354, "displayName" : "GNB1:GNGT1", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1738, "y" : 282 }, "minX" : 1672, "maxX" : 1789, "minY" : 265, "maxY" : 303, "prop" : { "x" : 1694, "y" : 271, "width" : 89, "height" : 22 }, "textPosition" : { "x" : 1694, "y" : 272 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1783, "y" : 271 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1783, "y" : 271 } } }, "connectors" : [ { "edgeId" : 128346, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1717, "y" : 296 }, "to" : { "x" : 1699, "y" : 303 } }, { "from" : { "x" : 1699, "y" : 303 }, "to" : { "x" : 1672, "y" : 273 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1712, "y" : 302 }, "b" : { "x" : 1717, "y" : 296 }, "c" : { "x" : 1709, "y" : 295 }, "type" : "ARROW", "centre" : { "x" : 1709, "y" : 295 } } } ] }, { "id" : 128351, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2271, "y" : 214 }, "minX" : 2222, "maxX" : 2300, "minY" : 176, "maxY" : 286, "prop" : { "x" : 2250, "y" : 199, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 2254, "y" : 203 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2288, "y" : 204 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2288, "y" : 204 } } }, "connectors" : [ { "edgeId" : 128350, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2282, "y" : 196 }, "to" : { "x" : 2300, "y" : 176 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128383, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2260, "y" : 232 }, "to" : { "x" : 2222, "y" : 286 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 128353, "reactomeId" : 113578, "displayName" : "GMP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2056, "y" : 177 }, "minX" : 2001, "maxX" : 2112, "minY" : 154, "maxY" : 199, "prop" : { "x" : 2001, "y" : 155, "width" : 110, "height" : 44 }, "textPosition" : { "x" : 2038, "y" : 166 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2106, "y" : 160 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2106, "y" : 160 } } }, "connectors" : [ { "edgeId" : 128350, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128352, "reactomeId" : 30991, "displayName" : "cGMP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2621, "y" : 176 }, "minX" : 2300, "maxX" : 2663, "minY" : 160, "maxY" : 237, "prop" : { "x" : 2597, "y" : 161, "width" : 49, "height" : 30 }, "textPosition" : { "x" : 2600, "y" : 165 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2641, "y" : 166 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2641, "y" : 166 } } }, "connectors" : [ { "edgeId" : 128391, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2631, "y" : 194 }, "to" : { "x" : 2663, "y" : 237 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2638, "y" : 197 }, "b" : { "x" : 2631, "y" : 194 }, "c" : { "x" : 2632, "y" : 202 }, "type" : "ARROW", "centre" : { "x" : 2632, "y" : 202 } } }, { "edgeId" : 128350, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2594, "y" : 176 }, "to" : { "x" : 2300, "y" : 176 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128354, "reactomeId" : 10563831, "displayName" : "GNAT1-GTP:PDE6", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2118, "y" : 288 }, "minX" : 2060, "maxX" : 2262, "minY" : 184, "maxY" : 315, "prop" : { "x" : 2060, "y" : 277, "width" : 117, "height" : 22 }, "textPosition" : { "x" : 2061, "y" : 278 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2177, "y" : 277 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2177, "y" : 277 } } }, "connectors" : [ { "edgeId" : 128350, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 2117, "y" : 274 }, "to" : { "x" : 2117, "y" : 192 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 2117, "y" : 188 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2117, "y" : 188 } } }, { "edgeId" : 128383, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2180, "y" : 286 }, "to" : { "x" : 2222, "y" : 286 } } ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128383, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 2175, "y" : 302 }, "to" : { "x" : 2259, "y" : 315 } }, { "from" : { "x" : 2259, "y" : 315 }, "to" : { "x" : 2259, "y" : 302 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 2258, "y" : 298 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2258, "y" : 298 } } } ] }, { "id" : 128357, "reactomeId" : 174390, "displayName" : "L-Met", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1243, "y" : 598 }, "minX" : 1186, "maxX" : 1270, "minY" : 564, "maxY" : 613, "prop" : { "x" : 1218, "y" : 583, "width" : 51, "height" : 30 }, "textPosition" : { "x" : 1223, "y" : 587 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1264, "y" : 588 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1264, "y" : 588 } } }, "connectors" : [ { "edgeId" : 128355, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1215, "y" : 582 }, "to" : { "x" : 1186, "y" : 564 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1207, "y" : 582 }, "b" : { "x" : 1215, "y" : 582 }, "c" : { "x" : 1211, "y" : 575 }, "type" : "ARROW", "centre" : { "x" : 1211, "y" : 575 } } } ] }, { "id" : 128356, "reactomeId" : 10604498, "displayName" : "GNAT1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1076, "y" : 565 }, "minX" : 1051, "maxX" : 1108, "minY" : 548, "maxY" : 576, "prop" : { "x" : 1051, "y" : 554, "width" : 51, "height" : 22 }, "textPosition" : { "x" : 1052, "y" : 554 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1102, "y" : 554 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1102, "y" : 554 } } }, "connectors" : [ { "edgeId" : 128355, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128359, "reactomeId" : 10604512, "displayName" : "METAP1/2", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1147, "y" : 607 }, "minX" : 1112, "maxX" : 1183, "minY" : 572, "maxY" : 618, "prop" : { "x" : 1112, "y" : 596, "width" : 71, "height" : 22 }, "textPosition" : { "x" : 1113, "y" : 596 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "connectors" : [ { "edgeId" : 128355, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1147, "y" : 590 }, "to" : { "x" : 1147, "y" : 580 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1148, "y" : 576 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1148, "y" : 576 } } } ] }, { "id" : 128358, "reactomeId" : 10604487, "displayName" : "GNAT1 (Met removed)", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1281, "y" : 516 }, "minX" : 1186, "maxX" : 1330, "minY" : 485, "maxY" : 564, "prop" : { "x" : 1239, "y" : 498, "width" : 84, "height" : 36 }, "textPosition" : { "x" : 1239, "y" : 498 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1323, "y" : 498 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1323, "y" : 498 } } }, "connectors" : [ { "edgeId" : 128355, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1245, "y" : 537 }, "to" : { "x" : 1186, "y" : 564 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1240, "y" : 544 }, "b" : { "x" : 1245, "y" : 537 }, "c" : { "x" : 1237, "y" : 536 }, "type" : "ARROW", "centre" : { "x" : 1237, "y" : 536 } } }, { "edgeId" : 128360, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1309, "y" : 495 }, "to" : { "x" : 1330, "y" : 485 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128361, "reactomeId" : 184174, "displayName" : "MYS-CoA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1265, "y" : 450 }, "minX" : 1230, "maxX" : 1330, "minY" : 434, "maxY" : 485, "prop" : { "x" : 1230, "y" : 435, "width" : 70, "height" : 31 }, "textPosition" : { "x" : 1234, "y" : 440 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1295, "y" : 440 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1295, "y" : 440 } } }, "connectors" : [ { "edgeId" : 128360, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1293, "y" : 469 }, "to" : { "x" : 1330, "y" : 485 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128363, "reactomeId" : 76194, "displayName" : "CoA-SH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1482, "y" : 453 }, "minX" : 1399, "maxX" : 1514, "minY" : 437, "maxY" : 476, "prop" : { "x" : 1451, "y" : 438, "width" : 62, "height" : 30 }, "textPosition" : { "x" : 1455, "y" : 442 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1508, "y" : 443 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1508, "y" : 443 } } }, "connectors" : [ { "edgeId" : 128360, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1448, "y" : 461 }, "to" : { "x" : 1399, "y" : 476 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1443, "y" : 467 }, "b" : { "x" : 1448, "y" : 461 }, "c" : { "x" : 1440, "y" : 459 }, "type" : "ARROW", "centre" : { "x" : 1440, "y" : 459 } } } ] }, { "id" : 128362, "reactomeId" : 10563811, "displayName" : "N-(C14:0)-GNAT1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1407, "y" : 396 }, "minX" : 1348, "maxX" : 1472, "minY" : 379, "maxY" : 476, "prop" : { "x" : 1348, "y" : 385, "width" : 118, "height" : 22 }, "textPosition" : { "x" : 1351, "y" : 385 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1466, "y" : 385 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1466, "y" : 385 } } }, "connectors" : [ { "edgeId" : 128360, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1405, "y" : 410 }, "to" : { "x" : 1399, "y" : 476 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1408, "y" : 417 }, "b" : { "x" : 1405, "y" : 410 }, "c" : { "x" : 1400, "y" : 417 }, "type" : "ARROW", "centre" : { "x" : 1400, "y" : 417 } } } ] }, { "id" : 128364, "reactomeId" : 10604493, "displayName" : "NMT1/2", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1361, "y" : 435 }, "minX" : 1332, "maxX" : 1390, "minY" : 424, "maxY" : 468, "prop" : { "x" : 1332, "y" : 424, "width" : 58, "height" : 22 }, "textPosition" : { "x" : 1334, "y" : 424 }, "connectors" : [ { "edgeId" : 128360, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1361, "y" : 452 }, "to" : { "x" : 1361, "y" : 460 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1361, "y" : 464 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1361, "y" : 464 } } } ] }, { "id" : 128367, "reactomeId" : 2530486, "displayName" : "FPP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1067, "y" : 445 }, "minX" : 1049, "maxX" : 1101, "minY" : 429, "maxY" : 460, "prop" : { "x" : 1049, "y" : 430, "width" : 37, "height" : 30 }, "textPosition" : { "x" : 1052, "y" : 434 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1081, "y" : 435 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1081, "y" : 435 } } }, "connectors" : [ { "edgeId" : 128365, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1089, "y" : 436 }, "to" : { "x" : 1101, "y" : 429 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128366, "reactomeId" : 10604474, "displayName" : "gngt1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1076, "y" : 396 }, "minX" : 1050, "maxX" : 1108, "minY" : 379, "maxY" : 429, "prop" : { "x" : 1050, "y" : 385, "width" : 52, "height" : 22 }, "textPosition" : { "x" : 1053, "y" : 385 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1102, "y" : 385 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1102, "y" : 385 } } }, "connectors" : [ { "edgeId" : 128365, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1084, "y" : 410 }, "to" : { "x" : 1101, "y" : 429 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128369, "reactomeId" : 111294, "displayName" : "PPi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1185, "y" : 465 }, "minX" : 1155, "maxX" : 1203, "minY" : 429, "maxY" : 480, "prop" : { "x" : 1168, "y" : 450, "width" : 34, "height" : 30 }, "textPosition" : { "x" : 1171, "y" : 454 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1197, "y" : 455 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1197, "y" : 455 } } }, "connectors" : [ { "edgeId" : 128365, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1172, "y" : 447 }, "to" : { "x" : 1155, "y" : 429 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1164, "y" : 445 }, "b" : { "x" : 1172, "y" : 447 }, "c" : { "x" : 1170, "y" : 439 }, "type" : "ARROW", "centre" : { "x" : 1170, "y" : 439 } } } ] }, { "id" : 128368, "reactomeId" : 10604352, "displayName" : "gngt1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1205, "y" : 397 }, "minX" : 1155, "maxX" : 1259, "minY" : 380, "maxY" : 429, "prop" : { "x" : 1158, "y" : 386, "width" : 95, "height" : 22 }, "textPosition" : { "x" : 1183, "y" : 386 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1253, "y" : 386 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1253, "y" : 386 } } }, "connectors" : [ { "edgeId" : 128365, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1187, "y" : 411 }, "to" : { "x" : 1155, "y" : 429 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1183, "y" : 418 }, "b" : { "x" : 1187, "y" : 411 }, "c" : { "x" : 1179, "y" : 411 }, "type" : "ARROW", "centre" : { "x" : 1179, "y" : 411 } } } ] }, { "id" : 128370, "reactomeId" : 10604480, "displayName" : "FNTA:FNTB", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1126, "y" : 497 }, "minX" : 1089, "maxX" : 1169, "minY" : 437, "maxY" : 508, "prop" : { "x" : 1089, "y" : 486, "width" : 74, "height" : 22 }, "textPosition" : { "x" : 1089, "y" : 487 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1163, "y" : 486 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1163, "y" : 486 } } }, "connectors" : [ { "edgeId" : 128365, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1126, "y" : 483 }, "to" : { "x" : 1127, "y" : 445 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1127, "y" : 441 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1127, "y" : 441 } } } ] }, { "id" : 128373, "reactomeId" : 10563842, "displayName" : "rho", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1376, "y" : 285 }, "minX" : 1329, "maxX" : 1825, "minY" : 268, "maxY" : 397, "prop" : { "x" : 1329, "y" : 274, "width" : 95, "height" : 22 }, "textPosition" : { "x" : 1362, "y" : 274 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1424, "y" : 274 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1424, "y" : 274 } } }, "connectors" : [ { "edgeId" : 128416, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128371, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1394, "y" : 299 }, "to" : { "x" : 1445, "y" : 326 } }, { "from" : { "x" : 1445, "y" : 326 }, "to" : { "x" : 1825, "y" : 397 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128372, "reactomeId" : 113592, "displayName" : "ATP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1778, "y" : 424 }, "minX" : 1758, "maxX" : 1825, "minY" : 397, "maxY" : 439, "prop" : { "x" : 1758, "y" : 409, "width" : 40, "height" : 30 }, "textPosition" : { "x" : 1762, "y" : 413 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1793, "y" : 414 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1793, "y" : 414 } } }, "connectors" : [ { "edgeId" : 128371, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1801, "y" : 412 }, "to" : { "x" : 1825, "y" : 397 } } ], "stoichiometry" : { "value" : 3, "shape" : { "a" : { "x" : 1807, "y" : 398 }, "b" : { "x" : 1819, "y" : 410 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1813, "y" : 404 } } } } ] }, { "id" : 128375, "reactomeId" : 10604605, "displayName" : "phospho-rho", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 2011, "y" : 400 }, "minX" : 1906, "maxX" : 2076, "minY" : 376, "maxY" : 418, "prop" : { "x" : 1953, "y" : 382, "width" : 117, "height" : 36 }, "textPosition" : { "x" : 1967, "y" : 389 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2070, "y" : 382 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2070, "y" : 382 } } }, "connectors" : [ { "edgeId" : 128371, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1950, "y" : 398 }, "to" : { "x" : 1906, "y" : 397 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1943, "y" : 402 }, "b" : { "x" : 1950, "y" : 398 }, "c" : { "x" : 1943, "y" : 394 }, "type" : "ARROW", "centre" : { "x" : 1943, "y" : 394 } } } ] }, { "id" : 128374, "reactomeId" : 29370, "displayName" : "ADP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1956, "y" : 445 }, "minX" : 1906, "maxX" : 1978, "minY" : 397, "maxY" : 460, "prop" : { "x" : 1936, "y" : 430, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 1940, "y" : 434 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1972, "y" : 435 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1972, "y" : 435 } } }, "connectors" : [ { "edgeId" : 128371, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1940, "y" : 427 }, "to" : { "x" : 1906, "y" : 397 } } ], "stoichiometry" : { "value" : 3, "shape" : { "a" : { "x" : 1917, "y" : 406 }, "b" : { "x" : 1929, "y" : 418 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1923, "y" : 412 } } }, "endShape" : { "a" : { "x" : 1932, "y" : 425 }, "b" : { "x" : 1940, "y" : 427 }, "c" : { "x" : 1937, "y" : 419 }, "type" : "ARROW", "centre" : { "x" : 1937, "y" : 419 } } } ] }, { "id" : 128377, "reactomeId" : 74016, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1829, "y" : 439 }, "minX" : 1804, "maxX" : 1868, "minY" : 400, "maxY" : 454, "prop" : { "x" : 1804, "y" : 424, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 1808, "y" : 428 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1849, "y" : 429 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1849, "y" : 429 } } }, "connectors" : [ { "edgeId" : 128371, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 1844, "y" : 421 }, "to" : { "x" : 1865, "y" : 403 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1862, "y" : 400 }, "b" : { "x" : 1868, "y" : 406 }, "c" : { "x" : 1865, "y" : 403 }, "type" : "STOP", "centre" : { "x" : 1865, "y" : 403 } } } ] }, { "id" : 128376, "reactomeId" : 10604616, "displayName" : "GRK1,4,7", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 1855, "y" : 319 }, "minX" : 1822, "maxX" : 1888, "minY" : 308, "maxY" : 389, "prop" : { "x" : 1822, "y" : 308, "width" : 66, "height" : 22 }, "textPosition" : { "x" : 1823, "y" : 308 }, "connectors" : [ { "edgeId" : 128371, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 1857, "y" : 336 }, "to" : { "x" : 1868, "y" : 381 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 1869, "y" : 385 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1869, "y" : 385 } } } ] }, { "id" : 128379, "reactomeId" : 10604623, "displayName" : "S-farn-GRK1:RCVRN:Ca2+", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1985, "y" : 569 }, "minX" : 1874, "maxX" : 2036, "minY" : 402, "maxY" : 587, "prop" : { "x" : 1941, "y" : 551, "width" : 89, "height" : 36 }, "textPosition" : { "x" : 1942, "y" : 552 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2030, "y" : 551 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2030, "y" : 551 } } }, "connectors" : [ { "edgeId" : 128371, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 1973, "y" : 548 }, "to" : { "x" : 1877, "y" : 404 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1874, "y" : 406 }, "b" : { "x" : 1880, "y" : 402 }, "c" : { "x" : 1877, "y" : 404 }, "type" : "STOP", "centre" : { "x" : 1877, "y" : 404 } } } ] }, { "id" : 128378, "reactomeId" : 10604629, "displayName" : "p-MII:SAG", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2188, "y" : 393 }, "minX" : 1875, "maxX" : 2238, "minY" : 371, "maxY" : 480, "prop" : { "x" : 2155, "y" : 377, "width" : 66, "height" : 32 }, "textPosition" : { "x" : 2155, "y" : 388 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2221, "y" : 377 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2221, "y" : 377 } } }, "connectors" : [ { "edgeId" : 128371, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 2175, "y" : 412 }, "to" : { "x" : 2122, "y" : 480 } }, { "from" : { "x" : 2122, "y" : 480 }, "to" : { "x" : 1946, "y" : 480 } }, { "from" : { "x" : 1946, "y" : 480 }, "to" : { "x" : 1878, "y" : 404 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1875, "y" : 407 }, "b" : { "x" : 1881, "y" : 401 }, "c" : { "x" : 1878, "y" : 404 }, "type" : "STOP", "centre" : { "x" : 1878, "y" : 404 } } }, { "edgeId" : 128380, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2224, "y" : 395 }, "to" : { "x" : 2238, "y" : 397 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128381, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2207, "y" : 432 }, "minX" : 2186, "maxX" : 2238, "minY" : 397, "maxY" : 447, "prop" : { "x" : 2186, "y" : 417, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 2190, "y" : 421 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2224, "y" : 422 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2224, "y" : 422 } } }, "connectors" : [ { "edgeId" : 128380, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2220, "y" : 414 }, "to" : { "x" : 2238, "y" : 397 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 128382, "reactomeId" : 10604646, "displayName" : "p-RHO:SAG", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2324, "y" : 397 }, "minX" : 2251, "maxX" : 2369, "minY" : 380, "maxY" : 408, "prop" : { "x" : 2286, "y" : 386, "width" : 77, "height" : 22 }, "textPosition" : { "x" : 2287, "y" : 387 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2363, "y" : 386 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2363, "y" : 386 } } }, "connectors" : [ { "edgeId" : 128380, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2283, "y" : 397 }, "to" : { "x" : 2251, "y" : 397 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2276, "y" : 401 }, "b" : { "x" : 2283, "y" : 397 }, "c" : { "x" : 2276, "y" : 393 }, "type" : "ARROW", "centre" : { "x" : 2276, "y" : 393 } } } ] }, { "id" : 128385, "reactomeId" : 10563829, "displayName" : "PDE6", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1922, "y" : 282 }, "minX" : 1901, "maxX" : 2030, "minY" : 243, "maxY" : 293, "prop" : { "x" : 1901, "y" : 271, "width" : 42, "height" : 22 }, "textPosition" : { "x" : 1901, "y" : 272 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1943, "y" : 271 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1943, "y" : 271 } } }, "connectors" : [ { "edgeId" : 128383, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1946, "y" : 274 }, "to" : { "x" : 2030, "y" : 243 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1951, "y" : 268 }, "b" : { "x" : 1946, "y" : 274 }, "c" : { "x" : 1954, "y" : 275 }, "type" : "ARROW", "centre" : { "x" : 1954, "y" : 275 } } } ] }, { "id" : 128384, "reactomeId" : 29372, "displayName" : "Pi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1987, "y" : 214 }, "minX" : 1974, "maxX" : 2030, "minY" : 198, "maxY" : 243, "prop" : { "x" : 1974, "y" : 199, "width" : 27, "height" : 30 }, "textPosition" : { "x" : 1978, "y" : 203 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1996, "y" : 204 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1996, "y" : 204 } } }, "connectors" : [ { "edgeId" : 128383, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2004, "y" : 223 }, "to" : { "x" : 2030, "y" : 243 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2012, "y" : 224 }, "b" : { "x" : 2004, "y" : 223 }, "c" : { "x" : 2007, "y" : 230 }, "type" : "ARROW", "centre" : { "x" : 2007, "y" : 230 } } } ] }, { "id" : 128386, "reactomeId" : 10604635, "displayName" : "GNAT1-GDP", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 1999, "y" : 285 }, "minX" : 1958, "maxX" : 2047, "minY" : 243, "maxY" : 296, "prop" : { "x" : 1958, "y" : 274, "width" : 83, "height" : 22 }, "textPosition" : { "x" : 1960, "y" : 275 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2041, "y" : 274 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2041, "y" : 274 } } }, "connectors" : [ { "edgeId" : 128383, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2007, "y" : 271 }, "to" : { "x" : 2030, "y" : 243 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2008, "y" : 263 }, "b" : { "x" : 2007, "y" : 271 }, "c" : { "x" : 2014, "y" : 268 }, "type" : "ARROW", "centre" : { "x" : 2014, "y" : 268 } } } ] }, { "id" : 128389, "reactomeId" : 74016, "displayName" : "Ca2+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2930, "y" : 169 }, "minX" : 2871, "maxX" : 2956, "minY" : 153, "maxY" : 233, "prop" : { "x" : 2905, "y" : 154, "width" : 50, "height" : 30 }, "textPosition" : { "x" : 2909, "y" : 158 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2950, "y" : 159 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2950, "y" : 159 } } }, "connectors" : [ { "edgeId" : 128387, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2916, "y" : 187 }, "to" : { "x" : 2871, "y" : 233 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128388, "reactomeId" : 10604642, "displayName" : "GUCA", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 2903, "y" : 287 }, "minX" : 2871, "maxX" : 2924, "minY" : 233, "maxY" : 298, "prop" : { "x" : 2882, "y" : 276, "width" : 42, "height" : 22 }, "textPosition" : { "x" : 2882, "y" : 276 }, "connectors" : [ { "edgeId" : 128387, "type" : "INPUT", "segments" : [ { "from" : { "x" : 2896, "y" : 270 }, "to" : { "x" : 2871, "y" : 233 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128390, "reactomeId" : 10564267, "displayName" : "GUCA:Ca2+", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 2798, "y" : 284 }, "minX" : 2719, "maxX" : 2839, "minY" : 237, "maxY" : 295, "prop" : { "x" : 2758, "y" : 273, "width" : 81, "height" : 22 }, "textPosition" : { "x" : 2758, "y" : 273 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "connectors" : [ { "edgeId" : 128387, "type" : "OUTPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } }, { "edgeId" : 128391, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 2778, "y" : 267 }, "to" : { "x" : 2721, "y" : 241 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2719, "y" : 245 }, "b" : { "x" : 2723, "y" : 237 }, "c" : { "x" : 2721, "y" : 241 }, "type" : "STOP", "centre" : { "x" : 2721, "y" : 241 } } } ] }, { "id" : 128393, "reactomeId" : 111294, "displayName" : "PPi", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2611, "y" : 237 }, "minX" : 2594, "maxX" : 2663, "minY" : 221, "maxY" : 252, "prop" : { "x" : 2594, "y" : 222, "width" : 34, "height" : 30 }, "textPosition" : { "x" : 2597, "y" : 226 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2623, "y" : 227 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2623, "y" : 227 } } }, "connectors" : [ { "edgeId" : 128391, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 2631, "y" : 237 }, "to" : { "x" : 2663, "y" : 237 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2638, "y" : 233 }, "b" : { "x" : 2631, "y" : 237 }, "c" : { "x" : 2638, "y" : 241 }, "type" : "ARROW", "centre" : { "x" : 2638, "y" : 241 } } } ] }, { "id" : 128392, "reactomeId" : 29438, "displayName" : "GTP", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 2794, "y" : 237 }, "minX" : 2774, "maxX" : 2816, "minY" : 221, "maxY" : 252, "prop" : { "x" : 2774, "y" : 222, "width" : 41, "height" : 30 }, "textPosition" : { "x" : 2778, "y" : 226 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2810, "y" : 227 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2810, "y" : 227 } } }, "connectors" : [ { "edgeId" : 128391, "type" : "INPUT", "segments" : [ ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128395, "reactomeId" : 10564269, "displayName" : "guca1b", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 2680, "y" : 203 }, "minX" : 2651, "maxX" : 2716, "minY" : 186, "maxY" : 231, "prop" : { "x" : 2651, "y" : 192, "width" : 59, "height" : 22 }, "textPosition" : { "x" : 2653, "y" : 192 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2710, "y" : 192 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2710, "y" : 192 } } }, "connectors" : [ { "edgeId" : 128391, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 2690, "y" : 217 }, "to" : { "x" : 2706, "y" : 231 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2698, "y" : 229 }, "b" : { "x" : 2706, "y" : 231 }, "c" : { "x" : 2703, "y" : 223 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 2703, "y" : 223 } } } ] }, { "id" : 128394, "reactomeId" : 10564246, "displayName" : "gucy2d", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 2715, "y" : 284 }, "minX" : 2691, "maxX" : 2746, "minY" : 245, "maxY" : 295, "prop" : { "x" : 2691, "y" : 273, "width" : 49, "height" : 22 }, "textPosition" : { "x" : 2693, "y" : 267 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2740, "y" : 273 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2740, "y" : 273 } } }, "connectors" : [ { "edgeId" : 128391, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 2714, "y" : 267 }, "to" : { "x" : 2714, "y" : 253 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 2713, "y" : 249 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2713, "y" : 249 } } } ] }, { "id" : 128397, "reactomeId" : 10564275, "displayName" : "GCAP2:Ca2+", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2794, "y" : 164 }, "minX" : 2717, "maxX" : 2843, "minY" : 147, "maxY" : 234, "prop" : { "x" : 2751, "y" : 153, "width" : 86, "height" : 22 }, "textPosition" : { "x" : 2767, "y" : 140 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2837, "y" : 153 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2837, "y" : 153 } } }, "connectors" : [ { "edgeId" : 128391, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 2781, "y" : 178 }, "to" : { "x" : 2720, "y" : 231 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2717, "y" : 228 }, "b" : { "x" : 2723, "y" : 234 }, "c" : { "x" : 2720, "y" : 231 }, "type" : "STOP", "centre" : { "x" : 2720, "y" : 231 } } } ] }, { "id" : 128396, "reactomeId" : 10564271, "displayName" : "guca1ab.1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 2717, "y" : 176 }, "minX" : 2687, "maxX" : 2754, "minY" : 159, "maxY" : 228, "prop" : { "x" : 2687, "y" : 165, "width" : 61, "height" : 22 }, "textPosition" : { "x" : 2690, "y" : 159 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2748, "y" : 165 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2748, "y" : 165 } } }, "connectors" : [ { "edgeId" : 128391, "type" : "ACTIVATOR", "segments" : [ { "from" : { "x" : 2716, "y" : 190 }, "to" : { "x" : 2714, "y" : 228 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2710, "y" : 221 }, "b" : { "x" : 2714, "y" : 228 }, "c" : { "x" : 2718, "y" : 221 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 2718, "y" : 221 } } } ] }, { "id" : 128398, "reactomeId" : 10564273, "displayName" : "GCAP1:Ca2+", "schemaClass" : "Complex", "renderableClass" : "Complex", "position" : { "x" : 2823, "y" : 192 }, "minX" : 2720, "maxX" : 2872, "minY" : 175, "maxY" : 238, "prop" : { "x" : 2780, "y" : 181, "width" : 86, "height" : 22 }, "textPosition" : { "x" : 2796, "y" : 168 }, "bgColor" : { "r" : 204, "g" : 255, "b" : 255 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 2866, "y" : 181 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 2866, "y" : 181 } } }, "connectors" : [ { "edgeId" : 128391, "type" : "INHIBITOR", "segments" : [ { "from" : { "x" : 2796, "y" : 206 }, "to" : { "x" : 2721, "y" : 234 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 2720, "y" : 230 }, "b" : { "x" : 2722, "y" : 238 }, "c" : { "x" : 2721, "y" : 234 }, "type" : "STOP", "centre" : { "x" : 2721, "y" : 234 } } } ] }, { "id" : 128401, "reactomeId" : 29368, "displayName" : "O2", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 394, "y" : 602 }, "minX" : 377, "maxX" : 463, "minY" : 562, "maxY" : 617, "prop" : { "x" : 377, "y" : 587, "width" : 34, "height" : 30 }, "textPosition" : { "x" : 381, "y" : 591 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 406, "y" : 592 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 406, "y" : 592 } } }, "connectors" : [ { "edgeId" : 128399, "type" : "INPUT", "segments" : [ { "from" : { "x" : 414, "y" : 592 }, "to" : { "x" : 463, "y" : 562 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 128400, "reactomeId" : 6786220, "displayName" : "DHA", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 380, "y" : 563 }, "minX" : 359, "maxX" : 463, "minY" : 547, "maxY" : 578, "prop" : { "x" : 359, "y" : 548, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 363, "y" : 552 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 397, "y" : 553 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 397, "y" : 553 } } }, "connectors" : [ { "edgeId" : 128399, "type" : "INPUT", "segments" : [ { "from" : { "x" : 405, "y" : 562 }, "to" : { "x" : 463, "y" : 562 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128403, "reactomeId" : 70106, "displayName" : "H+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 430, "y" : 539 }, "minX" : 412, "maxX" : 463, "minY" : 523, "maxY" : 562, "prop" : { "x" : 412, "y" : 524, "width" : 36, "height" : 30 }, "textPosition" : { "x" : 416, "y" : 528 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 443, "y" : 529 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 443, "y" : 529 } } }, "connectors" : [ { "edgeId" : 128399, "type" : "INPUT", "segments" : [ { "from" : { "x" : 451, "y" : 551 }, "to" : { "x" : 463, "y" : 562 } } ], "stoichiometry" : { "value" : 1 } } ], "trivial" : true }, { "id" : 128402, "reactomeId" : 29364, "displayName" : "NADPH", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 442, "y" : 608 }, "minX" : 413, "maxX" : 473, "minY" : 562, "maxY" : 623, "prop" : { "x" : 413, "y" : 593, "width" : 59, "height" : 30 }, "textPosition" : { "x" : 417, "y" : 597 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 467, "y" : 598 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 467, "y" : 598 } } }, "connectors" : [ { "edgeId" : 128399, "type" : "INPUT", "segments" : [ { "from" : { "x" : 448, "y" : 590 }, "to" : { "x" : 463, "y" : 562 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128405, "reactomeId" : 29356, "displayName" : "H2O", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 595, "y" : 530 }, "minX" : 550, "maxX" : 618, "minY" : 514, "maxY" : 562, "prop" : { "x" : 574, "y" : 515, "width" : 43, "height" : 30 }, "textPosition" : { "x" : 578, "y" : 519 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 612, "y" : 520 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 612, "y" : 520 } } }, "connectors" : [ { "edgeId" : 128399, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 571, "y" : 545 }, "to" : { "x" : 550, "y" : 562 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 568, "y" : 552 }, "b" : { "x" : 571, "y" : 545 }, "c" : { "x" : 563, "y" : 546 }, "type" : "ARROW", "centre" : { "x" : 563, "y" : 546 } } } ], "trivial" : true }, { "id" : 128404, "reactomeId" : 6786225, "displayName" : "HDoHE", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 676, "y" : 566 }, "minX" : 550, "maxX" : 759, "minY" : 539, "maxY" : 592, "prop" : { "x" : 595, "y" : 540, "width" : 163, "height" : 52 }, "textPosition" : { "x" : 651, "y" : 555 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 753, "y" : 545 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 753, "y" : 545 } } }, "connectors" : [ { "edgeId" : 128399, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 592, "y" : 563 }, "to" : { "x" : 550, "y" : 562 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 585, "y" : 567 }, "b" : { "x" : 592, "y" : 563 }, "c" : { "x" : 585, "y" : 559 }, "type" : "ARROW", "centre" : { "x" : 585, "y" : 559 } } } ] }, { "id" : 128407, "reactomeId" : 10621556, "displayName" : "Homologues of CYP4V2", "schemaClass" : "DefinedSet", "renderableClass" : "EntitySet", "position" : { "x" : 508, "y" : 507 }, "minX" : 481, "maxX" : 536, "minY" : 496, "maxY" : 554, "prop" : { "x" : 481, "y" : 496, "width" : 55, "height" : 22 }, "textPosition" : { "x" : 479, "y" : 483 }, "connectors" : [ { "edgeId" : 128399, "type" : "CATALYST", "segments" : [ { "from" : { "x" : 508, "y" : 521 }, "to" : { "x" : 509, "y" : 546 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "c" : { "x" : 509, "y" : 550 }, "r" : 4, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 509, "y" : 550 } } } ] }, { "id" : 128406, "reactomeId" : 29366, "displayName" : "NADP+", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 588, "y" : 605 }, "minX" : 550, "maxX" : 619, "minY" : 562, "maxY" : 620, "prop" : { "x" : 558, "y" : 590, "width" : 60, "height" : 30 }, "textPosition" : { "x" : 562, "y" : 594 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 613, "y" : 595 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 613, "y" : 595 } } }, "connectors" : [ { "edgeId" : 128399, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 574, "y" : 587 }, "to" : { "x" : 550, "y" : 562 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 566, "y" : 585 }, "b" : { "x" : 574, "y" : 587 }, "c" : { "x" : 572, "y" : 579 }, "type" : "ARROW", "centre" : { "x" : 572, "y" : 579 } } } ] }, { "id" : 128409, "reactomeId" : 8960974, "displayName" : "11cRAL", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 906, "y" : 197 }, "minX" : 836, "maxX" : 938, "minY" : 181, "maxY" : 212, "prop" : { "x" : 876, "y" : 182, "width" : 61, "height" : 30 }, "textPosition" : { "x" : 880, "y" : 186 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 932, "y" : 187 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 932, "y" : 187 } } }, "connectors" : [ { "edgeId" : 128408, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 873, "y" : 196 }, "to" : { "x" : 836, "y" : 196 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 866, "y" : 200 }, "b" : { "x" : 873, "y" : 196 }, "c" : { "x" : 866, "y" : 192 }, "type" : "ARROW", "centre" : { "x" : 866, "y" : 192 } } } ] }, { "id" : 128411, "reactomeId" : 10584261, "displayName" : "opn1sw1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1498, "y" : 1178 }, "minX" : 1445, "maxX" : 1533, "minY" : 1161, "maxY" : 1287, "prop" : { "x" : 1469, "y" : 1167, "width" : 58, "height" : 22 }, "textPosition" : { "x" : 1470, "y" : 1161 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1527, "y" : 1167 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1527, "y" : 1167 } } }, "connectors" : [ { "edgeId" : 128410, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1492, "y" : 1192 }, "to" : { "x" : 1445, "y" : 1287 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128412, "reactomeId" : 10604064, "displayName" : "opn1sw1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1629, "y" : 1291 }, "minX" : 1479, "maxX" : 1690, "minY" : 1274, "maxY" : 1302, "prop" : { "x" : 1575, "y" : 1280, "width" : 109, "height" : 22 }, "textPosition" : { "x" : 1597, "y" : 1280 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1684, "y" : 1280 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1684, "y" : 1280 } } }, "connectors" : [ { "edgeId" : 128410, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1572, "y" : 1285 }, "to" : { "x" : 1479, "y" : 1275 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1565, "y" : 1288 }, "b" : { "x" : 1572, "y" : 1285 }, "c" : { "x" : 1566, "y" : 1280 }, "type" : "ARROW", "centre" : { "x" : 1566, "y" : 1280 } } } ] }, { "id" : 128415, "reactomeId" : 10604059, "displayName" : "opn1lw1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1628, "y" : 1221 }, "minX" : 1510, "maxX" : 1691, "minY" : 1204, "maxY" : 1248, "prop" : { "x" : 1572, "y" : 1210, "width" : 113, "height" : 22 }, "textPosition" : { "x" : 1598, "y" : 1210 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1685, "y" : 1210 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1685, "y" : 1210 } } }, "connectors" : [ { "edgeId" : 128413, "type" : "OUTPUT", "segments" : [ { "from" : { "x" : 1579, "y" : 1235 }, "to" : { "x" : 1510, "y" : 1248 } } ], "stoichiometry" : { "value" : 1 }, "endShape" : { "a" : { "x" : 1573, "y" : 1240 }, "b" : { "x" : 1579, "y" : 1235 }, "c" : { "x" : 1571, "y" : 1232 }, "type" : "ARROW", "centre" : { "x" : 1571, "y" : 1232 } } } ] }, { "id" : 128414, "reactomeId" : 10584255, "displayName" : "opn1lw1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1316, "y" : 1220 }, "minX" : 1285, "maxX" : 1385, "minY" : 1203, "maxY" : 1249, "prop" : { "x" : 1285, "y" : 1209, "width" : 62, "height" : 22 }, "textPosition" : { "x" : 1286, "y" : 1209 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1347, "y" : 1209 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1347, "y" : 1209 } } }, "connectors" : [ { "edgeId" : 128413, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1342, "y" : 1234 }, "to" : { "x" : 1385, "y" : 1249 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128417, "reactomeId" : 419777, "displayName" : "Photon", "schemaClass" : "SimpleEntity", "renderableClass" : "Chemical", "position" : { "x" : 1303, "y" : 12 }, "minX" : 1276, "maxX" : 1331, "minY" : 0, "maxY" : 286, "prop" : { "x" : 1276, "y" : 1, "width" : 54, "height" : 22 }, "textPosition" : { "x" : 1276, "y" : 1 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1325, "y" : 6 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1325, "y" : 6 } } }, "connectors" : [ { "edgeId" : 128416, "type" : "INPUT", "segments" : [ { "from" : { "x" : 1303, "y" : 26 }, "to" : { "x" : 1304, "y" : 286 } } ], "stoichiometry" : { "value" : 1 } } ] }, { "id" : 128466, "reactomeId" : 10604614, "displayName" : "S-farn-GRK1", "schemaClass" : "EntityWithAccessionedSequence", "renderableClass" : "Protein", "position" : { "x" : 1876, "y" : 479 }, "minX" : 1834, "maxX" : 1925, "minY" : 462, "maxY" : 490, "prop" : { "x" : 1834, "y" : 468, "width" : 85, "height" : 22 }, "textPosition" : { "x" : 1836, "y" : 468 }, "interactorsSummary" : { "type" : "TR", "shape" : { "c" : { "x" : 1919, "y" : 468 }, "r" : 6, "type" : "CIRCLE", "empty" : true, "centre" : { "x" : 1919, "y" : 468 } } }, "connectors" : [ ] }, { "id" : 128482, "reactomeId" : 10649336, "displayName" : "Retinoid metabolism and transport", "schemaClass" : "Pathway", "renderableClass" : "ProcessNode", "position" : { "x" : 63, "y" : 864 }, "minX" : 0, "maxX" : 127, "minY" : 826, "maxY" : 902, "prop" : { "x" : 0, "y" : 826, "width" : 127, "height" : 76 }, "textPosition" : { "x" : 3, "y" : 835 }, "connectors" : [ ] } ], "edges" : [ { "id" : 128321, "reactomeId" : 10604090, "displayName" : "AWAT2 transfers PALM to 11cROL forming 11cRPALM", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 383, "y" : 1095 }, "minX" : 377, "maxX" : 389, "minY" : 1066, "maxY" : 1129, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 383, "y" : 1066 }, "to" : { "x" : 383, "y" : 1095 } }, { "from" : { "x" : 383, "y" : 1095 }, "to" : { "x" : 383, "y" : 1129 } } ], "reactionShape" : { "a" : { "x" : 377, "y" : 1089 }, "b" : { "x" : 389, "y" : 1101 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 383, "y" : 1095 } }, "inputs" : [ { "id" : 128322, "points" : [ { "x" : 354, "y" : 1062 } ] }, { "id" : 128323, "points" : [ { "x" : 383, "y" : 1039 } ] } ], "outputs" : [ { "id" : 128324, "points" : [ { "x" : 359, "y" : 1133 } ] }, { "id" : 128325, "points" : [ { "x" : 383, "y" : 1167 } ] } ], "catalysts" : [ { "id" : 128326, "points" : [ { "x" : 419, "y" : 1095 } ] } ] }, { "id" : 128387, "reactomeId" : 10604644, "displayName" : "GUCA binds Ca2+ to form GUCA:Ca2+", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2871, "y" : 231 }, "minX" : 2813, "maxX" : 2877, "minY" : 225, "maxY" : 267, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2871, "y" : 233 }, "to" : { "x" : 2870, "y" : 233 } }, { "from" : { "x" : 2870, "y" : 233 }, "to" : { "x" : 2871, "y" : 231 } }, { "from" : { "x" : 2871, "y" : 231 }, "to" : { "x" : 2813, "y" : 267 } } ], "endShape" : { "a" : { "x" : 2817, "y" : 260 }, "b" : { "x" : 2813, "y" : 267 }, "c" : { "x" : 2821, "y" : 267 }, "type" : "ARROW", "centre" : { "x" : 2821, "y" : 267 } }, "reactionShape" : { "a" : { "x" : 2865, "y" : 225 }, "b" : { "x" : 2877, "y" : 237 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2871, "y" : 231 } }, "inputs" : [ { "id" : 128388, "points" : [ { "x" : 2896, "y" : 270 } ] }, { "id" : 128389, "points" : [ { "x" : 2916, "y" : 187 } ] } ], "outputs" : [ { "id" : 128390 } ] }, { "id" : 128263, "reactomeId" : 10604009, "displayName" : "TTR:RBP:atROL binds to STRA6 receptor", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 299, "y" : 796 }, "minX" : 269, "maxX" : 324, "minY" : 790, "maxY" : 802, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 275, "y" : 796 }, "to" : { "x" : 299, "y" : 796 } }, { "from" : { "x" : 299, "y" : 796 }, "to" : { "x" : 324, "y" : 796 } } ], "endShape" : { "a" : { "x" : 317, "y" : 800 }, "b" : { "x" : 324, "y" : 796 }, "c" : { "x" : 317, "y" : 792 }, "type" : "ARROW", "centre" : { "x" : 317, "y" : 792 } }, "reactionShape" : { "c" : { "x" : 299, "y" : 796 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 299, "y" : 796 } }, "inputs" : [ { "id" : 128264, "points" : [ { "x" : 230, "y" : 848 } ] }, { "id" : 128265, "points" : [ { "x" : 235, "y" : 775 } ] } ], "outputs" : [ { "id" : 128266 } ] }, { "id" : 128391, "reactomeId" : 10564277, "displayName" : "GUCYs converts GTP to cGMP", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2713, "y" : 237 }, "minX" : 2663, "maxX" : 2771, "minY" : 231, "maxY" : 243, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2771, "y" : 237 }, "to" : { "x" : 2713, "y" : 237 } }, { "from" : { "x" : 2713, "y" : 237 }, "to" : { "x" : 2663, "y" : 237 } } ], "reactionShape" : { "a" : { "x" : 2707, "y" : 231 }, "b" : { "x" : 2719, "y" : 243 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2713, "y" : 237 } }, "inputs" : [ { "id" : 128392 } ], "outputs" : [ { "id" : 128393, "points" : [ { "x" : 2631, "y" : 237 } ] }, { "id" : 128352, "points" : [ { "x" : 2631, "y" : 194 } ] } ], "catalysts" : [ { "id" : 128394, "points" : [ { "x" : 2714, "y" : 267 } ] } ], "inhibitors" : [ { "id" : 128390, "points" : [ { "x" : 2778, "y" : 267 } ] }, { "id" : 128397, "points" : [ { "x" : 2781, "y" : 178 } ] }, { "id" : 128398, "points" : [ { "x" : 2796, "y" : 206 } ] } ], "activators" : [ { "id" : 128395, "points" : [ { "x" : 2690, "y" : 217 } ] }, { "id" : 128396, "points" : [ { "x" : 2716, "y" : 190 } ] } ] }, { "id" : 128327, "reactomeId" : 10604092, "displayName" : "OPN1LW binds 11cRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1397, "y" : 1263 }, "minX" : 1391, "maxX" : 1496, "minY" : 1257, "maxY" : 1269, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1397, "y" : 1263 }, "to" : { "x" : 1447, "y" : 1263 } }, { "from" : { "x" : 1447, "y" : 1263 }, "to" : { "x" : 1496, "y" : 1263 } } ], "reactionShape" : { "a" : { "x" : 1391, "y" : 1257 }, "b" : { "x" : 1403, "y" : 1269 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1397, "y" : 1263 } }, "inputs" : [ { "id" : 128328, "points" : [ { "x" : 1413, "y" : 1222 } ] }, { "id" : 128329, "points" : [ { "x" : 1306, "y" : 1263 } ] } ], "outputs" : [ { "id" : 128330, "points" : [ { "x" : 1572, "y" : 1258 } ] }, { "id" : 128331, "points" : [ { "x" : 1508, "y" : 1291 } ] } ] }, { "id" : 128267, "reactomeId" : 10604007, "displayName" : "STRA6 transports atROL from extracellular region to cytosol", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 473, "y" : 796 }, "minX" : 439, "maxX" : 499, "minY" : 790, "maxY" : 802, "reactionType" : "dissociation", "segments" : [ { "from" : { "x" : 439, "y" : 796 }, "to" : { "x" : 473, "y" : 796 } }, { "from" : { "x" : 473, "y" : 796 }, "to" : { "x" : 499, "y" : 796 } } ], "reactionShape" : { "c" : { "x" : 473, "y" : 796 }, "r" : 5, "r1" : 3, "type" : "DOUBLE_CIRCLE", "empty" : true, "centre" : { "x" : 473, "y" : 796 } }, "inputs" : [ { "id" : 128266 } ], "outputs" : [ { "id" : 128268, "points" : [ { "x" : 525, "y" : 796 } ] }, { "id" : 128269, "points" : [ { "x" : 499, "y" : 747 } ] } ] }, { "id" : 128332, "reactomeId" : 10604081, "displayName" : "Photons induce isomerisation of 11c-retinyl to at-retinyl", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1932, "y" : 1200 }, "minX" : 1926, "maxX" : 1938, "minY" : 1139, "maxY" : 1250, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1932, "y" : 1250 }, "to" : { "x" : 1932, "y" : 1200 } }, { "from" : { "x" : 1932, "y" : 1200 }, "to" : { "x" : 1930, "y" : 1139 } } ], "endShape" : { "a" : { "x" : 1934, "y" : 1146 }, "b" : { "x" : 1930, "y" : 1139 }, "c" : { "x" : 1926, "y" : 1146 }, "type" : "ARROW", "centre" : { "x" : 1926, "y" : 1146 } }, "reactionShape" : { "a" : { "x" : 1926, "y" : 1194 }, "b" : { "x" : 1938, "y" : 1206 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1932, "y" : 1200 } }, "inputs" : [ { "id" : 128333, "points" : [ { "x" : 1869, "y" : 1250 } ] }, { "id" : 128334, "points" : [ { "x" : 1874, "y" : 1354 } ] } ], "outputs" : [ { "id" : 128335 } ] }, { "id" : 128399, "reactomeId" : 10621559, "displayName" : "CYP4V2 omega-hydroxylates DHA to HDoHE", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 509, "y" : 562 }, "minX" : 463, "maxX" : 550, "minY" : 556, "maxY" : 568, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 463, "y" : 562 }, "to" : { "x" : 509, "y" : 562 } }, { "from" : { "x" : 509, "y" : 562 }, "to" : { "x" : 550, "y" : 562 } } ], "reactionShape" : { "a" : { "x" : 503, "y" : 556 }, "b" : { "x" : 515, "y" : 568 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 509, "y" : 562 } }, "inputs" : [ { "id" : 128400, "points" : [ { "x" : 405, "y" : 562 } ] }, { "id" : 128401, "points" : [ { "x" : 414, "y" : 592 } ] }, { "id" : 128402, "points" : [ { "x" : 448, "y" : 590 } ] }, { "id" : 128403, "points" : [ { "x" : 451, "y" : 551 } ] } ], "outputs" : [ { "id" : 128404, "points" : [ { "x" : 592, "y" : 563 } ] }, { "id" : 128405, "points" : [ { "x" : 571, "y" : 545 } ] }, { "id" : 128406, "points" : [ { "x" : 574, "y" : 587 } ] } ], "catalysts" : [ { "id" : 128407, "points" : [ { "x" : 508, "y" : 521 } ] } ] }, { "id" : 128270, "reactomeId" : 10564221, "displayName" : "atROL binds RBP1 to form RBP1:atROL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 396, "y" : 729 }, "minX" : 364, "maxX" : 402, "minY" : 723, "maxY" : 735, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 397, "y" : 729 }, "to" : { "x" : 396, "y" : 729 } }, { "from" : { "x" : 396, "y" : 729 }, "to" : { "x" : 364, "y" : 729 } } ], "endShape" : { "a" : { "x" : 371, "y" : 725 }, "b" : { "x" : 364, "y" : 729 }, "c" : { "x" : 371, "y" : 733 }, "type" : "ARROW", "centre" : { "x" : 371, "y" : 733 } }, "reactionShape" : { "c" : { "x" : 396, "y" : 729 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 396, "y" : 729 } }, "inputs" : [ { "id" : 128269, "points" : [ { "x" : 472, "y" : 729 } ] }, { "id" : 128271, "points" : [ { "x" : 419, "y" : 707 } ] } ], "outputs" : [ { "id" : 128272 } ] }, { "id" : 128273, "reactomeId" : 10603997, "displayName" : "LRAT esterifies RBP1:atROL and FACYLs to atREs", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 317, "y" : 524 }, "minX" : 302, "maxX" : 323, "minY" : 464, "maxY" : 617, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 318, "y" : 617 }, "to" : { "x" : 317, "y" : 524 } }, { "from" : { "x" : 317, "y" : 524 }, "to" : { "x" : 302, "y" : 464 } } ], "reactionShape" : { "a" : { "x" : 311, "y" : 518 }, "b" : { "x" : 323, "y" : 530 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 317, "y" : 524 } }, "inputs" : [ { "id" : 128274, "points" : [ { "x" : 255, "y" : 610 } ] }, { "id" : 128272, "points" : [ { "x" : 319, "y" : 715 } ] } ], "outputs" : [ { "id" : 128275, "points" : [ { "x" : 285, "y" : 402 } ] }, { "id" : 128276, "points" : [ { "x" : 271, "y" : 481 } ] } ], "catalysts" : [ { "id" : 128277, "points" : [ { "x" : 367, "y" : 509 } ] } ] }, { "id" : 128336, "reactomeId" : 10604145, "displayName" : "at-retinyl is hydrolysed from R* to release atRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1664, "y" : 1101 }, "minX" : 1600, "maxX" : 1696, "minY" : 1095, "maxY" : 1107, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1696, "y" : 1101 }, "to" : { "x" : 1664, "y" : 1101 } }, { "from" : { "x" : 1664, "y" : 1101 }, "to" : { "x" : 1600, "y" : 1101 } } ], "reactionShape" : { "a" : { "x" : 1658, "y" : 1095 }, "b" : { "x" : 1670, "y" : 1107 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1664, "y" : 1101 } }, "inputs" : [ { "id" : 128335, "points" : [ { "x" : 1873, "y" : 1111 } ] }, { "id" : 128337, "points" : [ { "x" : 1732, "y" : 1079 } ] } ], "outputs" : [ { "id" : 128338, "points" : [ { "x" : 1458, "y" : 1129 } ] }, { "id" : 128339, "points" : [ { "x" : 1562, "y" : 1061 } ] } ] }, { "id" : 128340, "reactomeId" : 10604099, "displayName" : "atRAL is reduced to atROL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1429, "y" : 1042 }, "minX" : 1358, "maxX" : 1467, "minY" : 1036, "maxY" : 1048, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1467, "y" : 1042 }, "to" : { "x" : 1429, "y" : 1042 } }, { "from" : { "x" : 1429, "y" : 1042 }, "to" : { "x" : 1358, "y" : 1042 } } ], "reactionShape" : { "a" : { "x" : 1423, "y" : 1036 }, "b" : { "x" : 1435, "y" : 1048 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1429, "y" : 1042 } }, "inputs" : [ { "id" : 128339, "points" : [ { "x" : 1522, "y" : 1042 } ] }, { "id" : 128341, "points" : [ { "x" : 1480, "y" : 1052 } ] }, { "id" : 128342, "points" : [ { "x" : 1480, "y" : 1028 } ] } ], "outputs" : [ { "id" : 128343, "points" : [ { "x" : 1324, "y" : 1032 } ] }, { "id" : 128344, "points" : [ { "x" : 1342, "y" : 1060 } ] } ], "catalysts" : [ { "id" : 128345, "points" : [ { "x" : 1429, "y" : 1004 } ] } ] }, { "id" : 128278, "reactomeId" : 10603995, "displayName" : "RPE65 isomero-hydrolyses atREs to 11cROL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 287, "y" : 278 }, "minX" : 281, "maxX" : 302, "minY" : 239, "maxY" : 335, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 288, "y" : 335 }, "to" : { "x" : 287, "y" : 278 } }, { "from" : { "x" : 287, "y" : 278 }, "to" : { "x" : 302, "y" : 239 } } ], "reactionShape" : { "a" : { "x" : 281, "y" : 272 }, "b" : { "x" : 293, "y" : 284 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 287, "y" : 278 } }, "inputs" : [ { "id" : 128279, "points" : [ { "x" : 388, "y" : 354 } ] }, { "id" : 128275, "points" : [ { "x" : 283, "y" : 365 } ] } ], "outputs" : [ { "id" : 128280, "points" : [ { "x" : 320, "y" : 195 } ] }, { "id" : 128281, "points" : [ { "x" : 328, "y" : 303 } ] }, { "id" : 128282, "points" : [ { "x" : 330, "y" : 228 } ] } ], "catalysts" : [ { "id" : 128283, "points" : [ { "x" : 240, "y" : 278 } ] } ] }, { "id" : 128408, "reactomeId" : 10636199, "displayName" : "RLBP1:11cRAL dissociates", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 838, "y" : 198 }, "minX" : 784, "maxX" : 844, "minY" : 172, "maxY" : 204, "reactionType" : "dissociation", "segments" : [ { "from" : { "x" : 784, "y" : 172 }, "to" : { "x" : 838, "y" : 198 } }, { "from" : { "x" : 838, "y" : 198 }, "to" : { "x" : 836, "y" : 196 } } ], "reactionShape" : { "c" : { "x" : 838, "y" : 198 }, "r" : 5, "r1" : 3, "type" : "DOUBLE_CIRCLE", "empty" : true, "centre" : { "x" : 838, "y" : 198 } }, "inputs" : [ { "id" : 128289 } ], "outputs" : [ { "id" : 128409, "points" : [ { "x" : 873, "y" : 196 } ] }, { "id" : 128285, "points" : [ { "x" : 352, "y" : 108 }, { "x" : 352, "y" : 65 }, { "x" : 806, "y" : 65 } ] } ] }, { "id" : 128346, "reactomeId" : 10604358, "displayName" : "Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1658, "y" : 276 }, "minX" : 1644, "maxX" : 1678, "minY" : 267, "maxY" : 279, "reactionType" : "dissociation", "segments" : [ { "from" : { "x" : 1644, "y" : 279 }, "to" : { "x" : 1658, "y" : 276 } }, { "from" : { "x" : 1658, "y" : 276 }, "to" : { "x" : 1672, "y" : 273 } } ], "reactionShape" : { "c" : { "x" : 1658, "y" : 276 }, "r" : 5, "r1" : 3, "type" : "DOUBLE_CIRCLE", "empty" : true, "centre" : { "x" : 1658, "y" : 276 } }, "inputs" : [ { "id" : 128347 } ], "outputs" : [ { "id" : 128348, "points" : [ { "x" : 1717, "y" : 296 }, { "x" : 1699, "y" : 303 } ] }, { "id" : 128349, "points" : [ { "x" : 1804, "y" : 273 }, { "x" : 1723, "y" : 257 } ] } ] }, { "id" : 128410, "reactomeId" : 10639957, "displayName" : "OPN1SW binds 11cRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1466, "y" : 1295 }, "minX" : 1445, "maxX" : 1479, "minY" : 1275, "maxY" : 1301, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1445, "y" : 1287 }, "to" : { "x" : 1466, "y" : 1295 } }, { "from" : { "x" : 1466, "y" : 1295 }, "to" : { "x" : 1479, "y" : 1275 } } ], "reactionShape" : { "a" : { "x" : 1460, "y" : 1289 }, "b" : { "x" : 1472, "y" : 1301 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1466, "y" : 1295 } }, "inputs" : [ { "id" : 128411, "points" : [ { "x" : 1492, "y" : 1192 } ] }, { "id" : 128329, "points" : [ { "x" : 1306, "y" : 1267 } ] } ], "outputs" : [ { "id" : 128412, "points" : [ { "x" : 1572, "y" : 1285 } ] }, { "id" : 128331, "points" : [ { "x" : 1499, "y" : 1291 } ] } ] }, { "id" : 128413, "reactomeId" : 10639959, "displayName" : "OPN1MW binds 11cRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1456, "y" : 1233 }, "minX" : 1385, "maxX" : 1510, "minY" : 1227, "maxY" : 1249, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1385, "y" : 1249 }, "to" : { "x" : 1456, "y" : 1233 } }, { "from" : { "x" : 1456, "y" : 1233 }, "to" : { "x" : 1510, "y" : 1248 } } ], "reactionShape" : { "a" : { "x" : 1450, "y" : 1227 }, "b" : { "x" : 1462, "y" : 1239 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1456, "y" : 1233 } }, "inputs" : [ { "id" : 128414, "points" : [ { "x" : 1342, "y" : 1234 } ] }, { "id" : 128329, "points" : [ { "x" : 1306, "y" : 1259 } ] } ], "outputs" : [ { "id" : 128415, "points" : [ { "x" : 1579, "y" : 1235 } ] }, { "id" : 128331, "points" : [ { "x" : 1513, "y" : 1291 } ] } ] }, { "id" : 128284, "reactomeId" : 10604032, "displayName" : "11cROL binds to RLBP1 to form RLBP1:11cROL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 401, "y" : 160 }, "minX" : 395, "maxX" : 435, "minY" : 154, "maxY" : 166, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 401, "y" : 161 }, "to" : { "x" : 401, "y" : 160 } }, { "from" : { "x" : 401, "y" : 160 }, "to" : { "x" : 435, "y" : 160 } } ], "endShape" : { "a" : { "x" : 428, "y" : 164 }, "b" : { "x" : 435, "y" : 160 }, "c" : { "x" : 428, "y" : 156 }, "type" : "ARROW", "centre" : { "x" : 428, "y" : 156 } }, "reactionShape" : { "c" : { "x" : 401, "y" : 160 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 401, "y" : 160 } }, "inputs" : [ { "id" : 128280, "points" : [ { "x" : 361, "y" : 170 } ] }, { "id" : 128285, "points" : [ { "x" : 366, "y" : 136 } ] } ], "outputs" : [ { "id" : 128286 } ] }, { "id" : 128287, "reactomeId" : 10564242, "displayName" : "RDH10,11 oxidise 11cROL to 11cRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 604, "y" : 158 }, "minX" : 575, "maxX" : 639, "minY" : 152, "maxY" : 164, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 575, "y" : 158 }, "to" : { "x" : 604, "y" : 158 } }, { "from" : { "x" : 604, "y" : 158 }, "to" : { "x" : 639, "y" : 158 } } ], "reactionShape" : { "a" : { "x" : 598, "y" : 152 }, "b" : { "x" : 610, "y" : 164 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 604, "y" : 158 } }, "inputs" : [ { "id" : 128286, "points" : [ { "x" : 538, "y" : 159 } ] }, { "id" : 128288, "points" : [ { "x" : 554, "y" : 143 } ] } ], "outputs" : [ { "id" : 128289, "points" : [ { "x" : 713, "y" : 158 } ] }, { "id" : 128290, "points" : [ { "x" : 647, "y" : 137 } ] }, { "id" : 128291, "points" : [ { "x" : 673, "y" : 140 } ] } ], "catalysts" : [ { "id" : 128292, "points" : [ { "x" : 605, "y" : 180 } ] } ] }, { "id" : 128350, "reactomeId" : 10563834, "displayName" : "PDE6 hydrolyses cGMP to GMP", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2117, "y" : 176 }, "minX" : 2111, "maxX" : 2300, "minY" : 170, "maxY" : 182, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2300, "y" : 176 }, "to" : { "x" : 2117, "y" : 176 } }, { "from" : { "x" : 2117, "y" : 176 }, "to" : { "x" : 2114, "y" : 176 } } ], "endShape" : { "a" : { "x" : 2121, "y" : 172 }, "b" : { "x" : 2114, "y" : 176 }, "c" : { "x" : 2121, "y" : 180 }, "type" : "ARROW", "centre" : { "x" : 2121, "y" : 180 } }, "reactionShape" : { "a" : { "x" : 2111, "y" : 170 }, "b" : { "x" : 2123, "y" : 182 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2117, "y" : 176 } }, "inputs" : [ { "id" : 128351, "points" : [ { "x" : 2282, "y" : 196 } ] }, { "id" : 128352, "points" : [ { "x" : 2594, "y" : 176 } ] } ], "outputs" : [ { "id" : 128353 } ], "catalysts" : [ { "id" : 128354, "points" : [ { "x" : 2117, "y" : 274 } ] } ] }, { "id" : 128416, "reactomeId" : 10563844, "displayName" : "Photons induce isomerization of 11c-retinyl to at-retinyl", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1315, "y" : 286 }, "minX" : 1304, "maxX" : 1326, "minY" : 280, "maxY" : 292, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1304, "y" : 286 }, "to" : { "x" : 1315, "y" : 286 } }, { "from" : { "x" : 1315, "y" : 286 }, "to" : { "x" : 1326, "y" : 285 } } ], "endShape" : { "a" : { "x" : 1319, "y" : 290 }, "b" : { "x" : 1326, "y" : 285 }, "c" : { "x" : 1319, "y" : 282 }, "type" : "ARROW", "centre" : { "x" : 1319, "y" : 282 } }, "reactionShape" : { "a" : { "x" : 1309, "y" : 280 }, "b" : { "x" : 1321, "y" : 292 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1315, "y" : 286 } }, "inputs" : [ { "id" : 128301, "points" : [ { "x" : 1294, "y" : 286 } ] }, { "id" : 128417, "points" : [ { "x" : 1303, "y" : 26 } ] } ], "outputs" : [ { "id" : 128373 } ] }, { "id" : 128355, "reactomeId" : 10604515, "displayName" : "METAP1/2 demethylates GNAT1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1148, "y" : 564 }, "minX" : 1105, "maxX" : 1186, "minY" : 558, "maxY" : 570, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1105, "y" : 564 }, "to" : { "x" : 1148, "y" : 564 } }, { "from" : { "x" : 1148, "y" : 564 }, "to" : { "x" : 1186, "y" : 564 } } ], "reactionShape" : { "a" : { "x" : 1142, "y" : 558 }, "b" : { "x" : 1154, "y" : 570 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1148, "y" : 564 } }, "inputs" : [ { "id" : 128356 } ], "outputs" : [ { "id" : 128357, "points" : [ { "x" : 1215, "y" : 582 } ] }, { "id" : 128358, "points" : [ { "x" : 1245, "y" : 537 } ] } ], "catalysts" : [ { "id" : 128359, "points" : [ { "x" : 1147, "y" : 590 } ] } ] }, { "id" : 128293, "reactomeId" : 10604028, "displayName" : "RDH5 oxidises 11cROL to 11cRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 612, "y" : 343 }, "minX" : 516, "maxX" : 685, "minY" : 337, "maxY" : 349, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 516, "y" : 343 }, "to" : { "x" : 612, "y" : 343 } }, { "from" : { "x" : 612, "y" : 343 }, "to" : { "x" : 685, "y" : 343 } } ], "reactionShape" : { "a" : { "x" : 606, "y" : 337 }, "b" : { "x" : 618, "y" : 349 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 612, "y" : 343 } }, "inputs" : [ { "id" : 128294, "points" : [ { "x" : 497, "y" : 354 } ] }, { "id" : 128286, "points" : [ { "x" : 487, "y" : 176 } ] } ], "outputs" : [ { "id" : 128295, "points" : [ { "x" : 689, "y" : 370 } ] }, { "id" : 128289, "points" : [ { "x" : 761, "y" : 172 }, { "x" : 735, "y" : 296 } ] }, { "id" : 128296, "points" : [ { "x" : 709, "y" : 350 } ] } ], "catalysts" : [ { "id" : 128297, "points" : [ { "x" : 612, "y" : 320 } ] } ] }, { "id" : 128360, "reactomeId" : 10604496, "displayName" : "NMT1/2 transfer MYS to GNAT1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1361, "y" : 476 }, "minX" : 1330, "maxX" : 1399, "minY" : 470, "maxY" : 485, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1330, "y" : 485 }, "to" : { "x" : 1361, "y" : 476 } }, { "from" : { "x" : 1361, "y" : 476 }, "to" : { "x" : 1399, "y" : 476 } } ], "reactionShape" : { "a" : { "x" : 1355, "y" : 470 }, "b" : { "x" : 1367, "y" : 482 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1361, "y" : 476 } }, "inputs" : [ { "id" : 128361, "points" : [ { "x" : 1293, "y" : 469 } ] }, { "id" : 128358, "points" : [ { "x" : 1309, "y" : 495 } ] } ], "outputs" : [ { "id" : 128362, "points" : [ { "x" : 1405, "y" : 410 } ] }, { "id" : 128363, "points" : [ { "x" : 1448, "y" : 461 } ] } ], "catalysts" : [ { "id" : 128364, "points" : [ { "x" : 1361, "y" : 452 } ] } ] }, { "id" : 128298, "reactomeId" : 10604030, "displayName" : "11cRAL binds to opsin to form 11c-retinyl:RHO", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1145, "y" : 285 }, "minX" : 1127, "maxX" : 1163, "minY" : 279, "maxY" : 291, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1127, "y" : 285 }, "to" : { "x" : 1145, "y" : 285 } }, { "from" : { "x" : 1145, "y" : 285 }, "to" : { "x" : 1163, "y" : 285 } } ], "reactionShape" : { "a" : { "x" : 1139, "y" : 279 }, "b" : { "x" : 1151, "y" : 291 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1145, "y" : 285 } }, "inputs" : [ { "id" : 128299, "points" : [ { "x" : 1113, "y" : 285 } ] }, { "id" : 128300, "points" : [ { "x" : 1096, "y" : 232 } ] } ], "outputs" : [ { "id" : 128301, "points" : [ { "x" : 1182, "y" : 285 } ] }, { "id" : 128302, "points" : [ { "x" : 1191, "y" : 315 } ] } ] }, { "id" : 128365, "reactomeId" : 10604483, "displayName" : "FNTA:FNTB transfers FARN to GNGT1", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1127, "y" : 429 }, "minX" : 1101, "maxX" : 1155, "minY" : 423, "maxY" : 435, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1101, "y" : 429 }, "to" : { "x" : 1127, "y" : 429 } }, { "from" : { "x" : 1127, "y" : 429 }, "to" : { "x" : 1155, "y" : 429 } } ], "reactionShape" : { "a" : { "x" : 1121, "y" : 423 }, "b" : { "x" : 1133, "y" : 435 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1127, "y" : 429 } }, "inputs" : [ { "id" : 128366, "points" : [ { "x" : 1084, "y" : 410 } ] }, { "id" : 128367, "points" : [ { "x" : 1089, "y" : 436 } ] } ], "outputs" : [ { "id" : 128368, "points" : [ { "x" : 1187, "y" : 411 } ] }, { "id" : 128369, "points" : [ { "x" : 1172, "y" : 447 } ] } ], "catalysts" : [ { "id" : 128370, "points" : [ { "x" : 1126, "y" : 483 } ] } ] }, { "id" : 128303, "reactomeId" : 10595637, "displayName" : "ABCA4 mediates atRAL transport", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1648, "y" : 467 }, "minX" : 1642, "maxX" : 1674, "minY" : 461, "maxY" : 522, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1674, "y" : 467 }, "to" : { "x" : 1648, "y" : 467 } }, { "from" : { "x" : 1648, "y" : 467 }, "to" : { "x" : 1668, "y" : 522 } } ], "reactionShape" : { "a" : { "x" : 1642, "y" : 461 }, "b" : { "x" : 1654, "y" : 473 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1648, "y" : 467 } }, "inputs" : [ { "id" : 128304, "points" : [ { "x" : 1703, "y" : 421 } ] }, { "id" : 128305, "points" : [ { "x" : 1693, "y" : 462 } ] }, { "id" : 128306, "points" : [ { "x" : 1695, "y" : 482 } ] } ], "outputs" : [ { "id" : 128307, "points" : [ { "x" : 1652, "y" : 543 } ] }, { "id" : 128308, "points" : [ { "x" : 1683, "y" : 554 } ] }, { "id" : 128309, "points" : [ { "x" : 1747, "y" : 567 } ] } ], "catalysts" : [ { "id" : 128310, "points" : [ { "x" : 1648, "y" : 415 } ] } ] }, { "id" : 128371, "reactomeId" : 10604631, "displayName" : "GRK1,4,7 phosphorylate MII to p-MII", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1872, "y" : 397 }, "minX" : 1825, "maxX" : 1906, "minY" : 391, "maxY" : 403, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1825, "y" : 397 }, "to" : { "x" : 1872, "y" : 397 } }, { "from" : { "x" : 1872, "y" : 397 }, "to" : { "x" : 1906, "y" : 397 } } ], "reactionShape" : { "a" : { "x" : 1866, "y" : 391 }, "b" : { "x" : 1878, "y" : 403 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1872, "y" : 397 } }, "inputs" : [ { "id" : 128372, "points" : [ { "x" : 1801, "y" : 412 } ], "stoichiometry" : 3 }, { "id" : 128373, "points" : [ { "x" : 1394, "y" : 299 }, { "x" : 1445, "y" : 326 } ] } ], "outputs" : [ { "id" : 128374, "points" : [ { "x" : 1940, "y" : 427 } ], "stoichiometry" : 3 }, { "id" : 128375, "points" : [ { "x" : 1950, "y" : 398 } ] } ], "catalysts" : [ { "id" : 128376, "points" : [ { "x" : 1857, "y" : 336 } ] } ], "inhibitors" : [ { "id" : 128377, "points" : [ { "x" : 1844, "y" : 421 } ] }, { "id" : 128378, "points" : [ { "x" : 2175, "y" : 412 }, { "x" : 2122, "y" : 480 }, { "x" : 1946, "y" : 480 } ] }, { "id" : 128379, "points" : [ { "x" : 1973, "y" : 548 } ] } ] }, { "id" : 128311, "reactomeId" : 10604043, "displayName" : "RDH12 reduces atRAL to atROL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 1908, "y" : 702 }, "minX" : 1888, "maxX" : 1918, "minY" : 635, "maxY" : 739, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 1888, "y" : 635 }, "to" : { "x" : 1908, "y" : 702 } }, { "from" : { "x" : 1908, "y" : 702 }, "to" : { "x" : 1918, "y" : 739 } } ], "reactionShape" : { "a" : { "x" : 1902, "y" : 696 }, "b" : { "x" : 1914, "y" : 708 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1908, "y" : 702 } }, "inputs" : [ { "id" : 128312, "points" : [ { "x" : 1868, "y" : 692 } ] }, { "id" : 128313, "points" : [ { "x" : 1863, "y" : 647 } ] }, { "id" : 128309, "points" : [ { "x" : 1803, "y" : 593 } ] } ], "outputs" : [ { "id" : 128314, "points" : [ { "x" : 1887, "y" : 786 } ] }, { "id" : 128315, "points" : [ { "x" : 1901, "y" : 747 } ] } ], "catalysts" : [ { "id" : 128316, "points" : [ { "x" : 2168, "y" : 822 } ] } ] }, { "id" : 128317, "reactomeId" : 10604103, "displayName" : "RLBP1 binds atROL to form RLBP1:atROL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 733, "y" : 1026 }, "minX" : 703, "maxX" : 759, "minY" : 1020, "maxY" : 1032, "reactionType" : "binding", "segments" : [ { "from" : { "x" : 759, "y" : 1025 }, "to" : { "x" : 733, "y" : 1026 } }, { "from" : { "x" : 733, "y" : 1026 }, "to" : { "x" : 703, "y" : 1026 } } ], "endShape" : { "a" : { "x" : 710, "y" : 1022 }, "b" : { "x" : 703, "y" : 1026 }, "c" : { "x" : 710, "y" : 1030 }, "type" : "ARROW", "centre" : { "x" : 710, "y" : 1030 } }, "reactionShape" : { "c" : { "x" : 733, "y" : 1026 }, "r" : 5, "type" : "CIRCLE", "centre" : { "x" : 733, "y" : 1026 } }, "inputs" : [ { "id" : 128318, "points" : [ { "x" : 786, "y" : 1025 } ] }, { "id" : 128319, "points" : [ { "x" : 773, "y" : 1056 } ] } ], "outputs" : [ { "id" : 128320 } ] }, { "id" : 128380, "reactomeId" : 10604648, "displayName" : "at-retinyl is hydrolysed from p-MII:SAG to release atRAL", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2244, "y" : 397 }, "minX" : 2238, "maxX" : 2257, "minY" : 391, "maxY" : 403, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2238, "y" : 397 }, "to" : { "x" : 2244, "y" : 397 } }, { "from" : { "x" : 2244, "y" : 397 }, "to" : { "x" : 2251, "y" : 397 } } ], "reactionShape" : { "a" : { "x" : 2238, "y" : 391 }, "b" : { "x" : 2250, "y" : 403 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2244, "y" : 397 } }, "inputs" : [ { "id" : 128381, "points" : [ { "x" : 2220, "y" : 414 } ] }, { "id" : 128378, "points" : [ { "x" : 2224, "y" : 395 } ] } ], "outputs" : [ { "id" : 128304, "points" : [ { "x" : 1731, "y" : 421 }, { "x" : 1843, "y" : 506 }, { "x" : 2232, "y" : 510 } ] }, { "id" : 128382, "points" : [ { "x" : 2283, "y" : 397 } ] } ] }, { "id" : 128383, "reactomeId" : 10604640, "displayName" : "GNAT1-GTP hydrolyses its bound GTP to GDP", "schemaClass" : "Reaction", "renderableClass" : "Reaction", "position" : { "x" : 2258, "y" : 286 }, "minX" : 2030, "maxX" : 2264, "minY" : 243, "maxY" : 292, "reactionType" : "transition", "segments" : [ { "from" : { "x" : 2222, "y" : 286 }, "to" : { "x" : 2258, "y" : 286 } }, { "from" : { "x" : 2258, "y" : 286 }, "to" : { "x" : 2233, "y" : 243 } }, { "from" : { "x" : 2233, "y" : 243 }, "to" : { "x" : 2030, "y" : 243 } } ], "reactionShape" : { "a" : { "x" : 2252, "y" : 280 }, "b" : { "x" : 2264, "y" : 292 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 2258, "y" : 286 } }, "inputs" : [ { "id" : 128351, "points" : [ { "x" : 2260, "y" : 232 } ] }, { "id" : 128354, "points" : [ { "x" : 2180, "y" : 286 } ] } ], "outputs" : [ { "id" : 128384, "points" : [ { "x" : 2004, "y" : 223 } ] }, { "id" : 128385, "points" : [ { "x" : 1946, "y" : 274 } ] }, { "id" : 128386, "points" : [ { "x" : 2007, "y" : 271 } ] } ], "catalysts" : [ { "id" : 128354, "points" : [ { "x" : 2175, "y" : 302 }, { "x" : 2259, "y" : 315 } ] } ] } ], "compartments" : [ { "id" : 128448, "reactomeId" : 263698, "displayName" : "phagolysosome", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1088, "y" : 906 }, "minX" : 1022, "maxX" : 1154, "minY" : 859, "maxY" : 954, "prop" : { "x" : 1022, "y" : 859, "width" : 132, "height" : 95 }, "textPosition" : { "x" : 1031, "y" : 906 }, "insets" : { "x" : 1032, "y" : 869, "width" : 112, "height" : 75 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 } }, { "id" : 128419, "reactomeId" : 17957, "displayName" : "endoplasmic reticulum lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 453, "y" : 467 }, "minX" : 381, "maxX" : 525, "minY" : 421, "maxY" : 514, "prop" : { "x" : 381, "y" : 421, "width" : 144, "height" : 93 }, "textPosition" : { "x" : 395, "y" : 437 }, "insets" : { "x" : 391, "y" : 431, "width" : 124, "height" : 73 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 128277, 128407 ] }, { "id" : 128483, "reactomeId" : 2514888, "displayName" : "photoreceptor disc membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1694, "y" : 1138 }, "minX" : 1357, "maxX" : 2031, "minY" : 1114, "maxY" : 1163, "prop" : { "x" : 1357, "y" : 1114, "width" : 674, "height" : 49 }, "textPosition" : { "x" : 1497, "y" : 1121 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 128338, 128335 ] }, { "id" : 128418, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 593, "y" : 442 }, "minX" : 216, "maxX" : 970, "minY" : 85, "maxY" : 800, "prop" : { "x" : 216, "y" : 85, "width" : 754, "height" : 715 }, "textPosition" : { "x" : 741, "y" : 450 }, "insets" : { "x" : 226, "y" : 95, "width" : 734, "height" : 695 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 128420, 128270, 128273, 128278, 128283, 128282, 128287, 128289, 128290, 128291, 128421, 128280, 128284, 128286, 128288, 128295, 128296, 128422, 128419, 128294, 128293, 128265, 128266, 128268, 128263, 128267, 128271, 128269, 128276, 128272, 128285, 128400, 128404, 128405, 128401, 128399, 128402, 128403, 128406, 128409, 128408, 128487, 128488, 128489, 128279, 128274 ] }, { "id" : 128421, "reactomeId" : 17957, "displayName" : "endoplasmic reticulum lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 621, "y" : 246 }, "minX" : 522, "maxX" : 720, "minY" : 191, "maxY" : 301, "prop" : { "x" : 522, "y" : 191, "width" : 198, "height" : 110 }, "textPosition" : { "x" : 521, "y" : 229 }, "insets" : { "x" : 532, "y" : 201, "width" : 178, "height" : 90 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 128292, 128297 ] }, { "id" : 128420, "reactomeId" : 13977, "displayName" : "lipid droplet", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 311, "y" : 352 }, "minX" : 240, "maxX" : 383, "minY" : 288, "maxY" : 417, "prop" : { "x" : 240, "y" : 288, "width" : 143, "height" : 129 }, "textPosition" : { "x" : 281, "y" : 343 }, "insets" : { "x" : 250, "y" : 298, "width" : 123, "height" : 109 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 128275, 128281 ] }, { "id" : 128423, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 2058, "y" : 448 }, "minX" : 1018, "maxX" : 3098, "minY" : 52, "maxY" : 844, "prop" : { "x" : 1018, "y" : 52, "width" : 2080, "height" : 792 }, "textPosition" : { "x" : 2289, "y" : 519 }, "insets" : { "x" : 1028, "y" : 62, "width" : 2060, "height" : 772 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 128300, 128305, 128306, 128307, 128308, 128309, 128303, 128311, 128312, 128424, 128316, 128453, 128456, 128346, 128350, 128353, 128389, 128357, 128355, 128359, 128360, 128363, 128364, 128356, 128358, 128365, 128369, 128370, 128367, 128351, 128466, 128384, 128391, 128352, 128315, 128314, 128393, 128392, 128387, 128313, 128377, 128476, 128379, 128381, 128372, 128374, 128396, 128397, 128398, 128395, 128361 ] }, { "id" : 128425, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 536, "y" : 1181 }, "minX" : 200, "maxX" : 872, "minY" : 979, "maxY" : 1383, "prop" : { "x" : 200, "y" : 979, "width" : 672, "height" : 404 }, "textPosition" : { "x" : 585, "y" : 1185 }, "insets" : { "x" : 210, "y" : 989, "width" : 652, "height" : 384 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 128320, 128317, 128323, 128427, 128426, 128321, 128322, 128324, 128318, 128325, 128319 ] }, { "id" : 128456, "reactomeId" : 2514888, "displayName" : "photoreceptor disc membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 2021, "y" : 342 }, "minX" : 1059, "maxX" : 2983, "minY" : 282, "maxY" : 403, "prop" : { "x" : 1059, "y" : 282, "width" : 1924, "height" : 121 }, "textPosition" : { "x" : 2298, "y" : 312 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 128465, 128371, 128380, 128383, 128298, 128485, 128416 ] }, { "id" : 128427, "reactomeId" : 17957, "displayName" : "endoplasmic reticulum lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 577, "y" : 1108 }, "minX" : 438, "maxX" : 717, "minY" : 1072, "maxY" : 1145, "prop" : { "x" : 438, "y" : 1072, "width" : 279, "height" : 73 }, "textPosition" : { "x" : 516, "y" : 1090 }, "insets" : { "x" : 448, "y" : 1082, "width" : 259, "height" : 53 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 128326 ] }, { "id" : 128465, "reactomeId" : 2514888, "displayName" : "photoreceptor disc membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 2021, "y" : 341 }, "minX" : 1068, "maxX" : 2974, "minY" : 290, "maxY" : 393, "prop" : { "x" : 1068, "y" : 290, "width" : 1906, "height" : 103 }, "textPosition" : { "x" : 2022, "y" : 317 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 128362, 128366, 128368, 128378, 128382, 128304, 128310, 128299, 128348, 128349, 128385, 128354, 128386, 128394, 128347, 128388, 128390, 128301, 128373, 128375, 128376, 128302 ] }, { "id" : 128432, "reactomeId" : 70101, "displayName" : "cytosol", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1543, "y" : 1162 }, "minX" : 956, "maxX" : 2131, "minY" : 987, "maxY" : 1338, "prop" : { "x" : 956, "y" : 987, "width" : 1175, "height" : 351 }, "textPosition" : { "x" : 979, "y" : 1059 }, "insets" : { "x" : 966, "y" : 997, "width" : 1155, "height" : 331 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 128436, 128327, 128339, 128340, 128344, 128341, 128342, 128332, 128343, 128345, 128483, 128337, 128336, 128329, 128333, 128414, 128411, 128328, 128330, 128412, 128415, 128490, 128491, 128492, 128331, 128410, 128413 ] }, { "id" : 128436, "reactomeId" : 17957, "displayName" : "endoplasmic reticulum lumen", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1170, "y" : 1105 }, "minX" : 1106, "maxX" : 1234, "minY" : 1065, "maxY" : 1146, "prop" : { "x" : 1106, "y" : 1065, "width" : 128, "height" : 81 }, "textPosition" : { "x" : 1111, "y" : 1083 }, "insets" : { "x" : 1116, "y" : 1075, "width" : 108, "height" : 61 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 128437 ] }, { "id" : 128474, "reactomeId" : 2514888, "displayName" : "photoreceptor disc membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1524, "y" : 652 }, "minX" : 1294, "maxX" : 1755, "minY" : 624, "maxY" : 680, "prop" : { "x" : 1294, "y" : 624, "width" : 461, "height" : 56 }, "textPosition" : { "x" : 1297, "y" : 635 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 } }, { "id" : 128476, "reactomeId" : 2514888, "displayName" : "photoreceptor disc membrane", "schemaClass" : "Compartment", "renderableClass" : "Compartment", "position" : { "x" : 1524, "y" : 652 }, "minX" : 1288, "maxX" : 1760, "minY" : 618, "maxY" : 687, "prop" : { "x" : 1288, "y" : 618, "width" : 472, "height" : 69 }, "textPosition" : { "x" : 1297, "y" : 635 }, "bgColor" : { "r" : 250, "g" : 240, "b" : 240 }, "componentIds" : [ 128474 ] } ], "notes" : [ { "id" : 128437, "displayName" : "Cone outer segment", "renderableClass" : "Note", "position" : { "x" : 1034, "y" : 1056 }, "minX" : 961, "maxX" : 1107, "minY" : 1041, "maxY" : 1071, "prop" : { "x" : 961, "y" : 1041, "width" : 146, "height" : 30 }, "textPosition" : { "x" : 965, "y" : 1045 } }, { "id" : 128453, "displayName" : "Rod inner segment", "renderableClass" : "Note", "position" : { "x" : 2319, "y" : 789 }, "minX" : 2282, "maxX" : 2357, "minY" : 771, "maxY" : 807, "prop" : { "x" : 2282, "y" : 771, "width" : 75, "height" : 36 }, "textPosition" : { "x" : 2283, "y" : 771 } }, { "id" : 128422, "displayName" : "RPE", "renderableClass" : "Note", "position" : { "x" : 768, "y" : 446 }, "minX" : 743, "maxX" : 793, "minY" : 435, "maxY" : 457, "prop" : { "x" : 743, "y" : 435, "width" : 50, "height" : 22 }, "textPosition" : { "x" : 752, "y" : 435 } }, { "id" : 128424, "displayName" : "Rod outer segment", "renderableClass" : "Note", "position" : { "x" : 1321, "y" : 713 }, "minX" : 1264, "maxX" : 1379, "minY" : 697, "maxY" : 730, "prop" : { "x" : 1264, "y" : 697, "width" : 115, "height" : 33 }, "textPosition" : { "x" : 1284, "y" : 696 } }, { "id" : 128426, "displayName" : "Muller cell", "renderableClass" : "Note", "position" : { "x" : 616, "y" : 1181 }, "minX" : 568, "maxX" : 664, "minY" : 1165, "maxY" : 1197, "prop" : { "x" : 568, "y" : 1165, "width" : 96, "height" : 32 }, "textPosition" : { "x" : 581, "y" : 1170 } } ], "links" : [ { "id" : 128485, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1865, "y" : 400 }, "minX" : 1856, "maxX" : 1874, "minY" : 336, "maxY" : 465, "segments" : [ { "from" : { "x" : 1874, "y" : 465 }, "to" : { "x" : 1856, "y" : 336 } } ], "reactionShape" : { "a" : { "x" : 1859, "y" : 394 }, "b" : { "x" : 1871, "y" : 406 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1865, "y" : 400 } }, "inputs" : [ { "id" : 128466 } ], "outputs" : [ { "id" : 128376 } ] }, { "id" : 128487, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1355, "y" : 1181 }, "minX" : 1327, "maxX" : 1383, "minY" : 1157, "maxY" : 1206, "segments" : [ { "from" : { "x" : 1327, "y" : 1206 }, "to" : { "x" : 1383, "y" : 1157 } } ], "reactionShape" : { "a" : { "x" : 1349, "y" : 1175 }, "b" : { "x" : 1361, "y" : 1187 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1355, "y" : 1181 } }, "inputs" : [ { "id" : 128414 } ], "outputs" : [ { "id" : 128338 } ] }, { "id" : 128486, "renderableClass" : "Interaction", "position" : { "x" : 148, "y" : 862 }, "minX" : 130, "maxX" : 166, "minY" : 856, "maxY" : 868, "interactionType" : "Activate", "segments" : [ { "from" : { "x" : 130, "y" : 862 }, "to" : { "x" : 166, "y" : 862 } } ], "endShape" : { "a" : { "x" : 159, "y" : 866 }, "b" : { "x" : 166, "y" : 862 }, "c" : { "x" : 159, "y" : 858 }, "type" : "ARROW", "empty" : true, "centre" : { "x" : 159, "y" : 858 } }, "reactionShape" : { "a" : { "x" : 142, "y" : 856 }, "b" : { "x" : 154, "y" : 868 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 148, "y" : 862 } }, "inputs" : [ { "id" : 128482 } ], "outputs" : [ { "id" : 128264 } ] }, { "id" : 128489, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1405, "y" : 1175 }, "minX" : 1398, "maxX" : 1412, "minY" : 1157, "maxY" : 1194, "segments" : [ { "from" : { "x" : 1412, "y" : 1194 }, "to" : { "x" : 1398, "y" : 1157 } } ], "reactionShape" : { "a" : { "x" : 1399, "y" : 1169 }, "b" : { "x" : 1411, "y" : 1181 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1405, "y" : 1175 } }, "inputs" : [ { "id" : 128328 } ], "outputs" : [ { "id" : 128338 } ] }, { "id" : 128488, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1443, "y" : 1163 }, "minX" : 1421, "maxX" : 1466, "minY" : 1157, "maxY" : 1170, "segments" : [ { "from" : { "x" : 1466, "y" : 1170 }, "to" : { "x" : 1421, "y" : 1157 } } ], "reactionShape" : { "a" : { "x" : 1437, "y" : 1157 }, "b" : { "x" : 1449, "y" : 1169 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1443, "y" : 1163 } }, "inputs" : [ { "id" : 128411 } ], "outputs" : [ { "id" : 128338 } ] }, { "id" : 128491, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1708, "y" : 1268 }, "minX" : 1670, "maxX" : 1746, "minY" : 1260, "maxY" : 1277, "segments" : [ { "from" : { "x" : 1670, "y" : 1277 }, "to" : { "x" : 1746, "y" : 1260 } } ], "reactionShape" : { "a" : { "x" : 1702, "y" : 1262 }, "b" : { "x" : 1714, "y" : 1274 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1708, "y" : 1268 } }, "inputs" : [ { "id" : 128412 } ], "outputs" : [ { "id" : 128333 } ] }, { "id" : 128490, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1716, "y" : 1252 }, "minX" : 1687, "maxX" : 1746, "minY" : 1246, "maxY" : 1258, "segments" : [ { "from" : { "x" : 1687, "y" : 1253 }, "to" : { "x" : 1746, "y" : 1251 } } ], "reactionShape" : { "a" : { "x" : 1710, "y" : 1246 }, "b" : { "x" : 1722, "y" : 1258 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1716, "y" : 1252 } }, "inputs" : [ { "id" : 128330 } ], "outputs" : [ { "id" : 128333 } ] }, { "id" : 128492, "renderableClass" : "EntitySetAndMemberLink", "position" : { "x" : 1717, "y" : 1235 }, "minX" : 1688, "maxX" : 1746, "minY" : 1229, "maxY" : 1241, "segments" : [ { "from" : { "x" : 1688, "y" : 1230 }, "to" : { "x" : 1746, "y" : 1240 } } ], "reactionShape" : { "a" : { "x" : 1711, "y" : 1229 }, "b" : { "x" : 1723, "y" : 1241 }, "type" : "BOX", "empty" : true, "centre" : { "x" : 1717, "y" : 1235 } }, "inputs" : [ { "id" : 128415 } ], "outputs" : [ { "id" : 128333 } ] } ], "shadows" : [ { "id" : 128493, "reactomeId" : 10647688, "displayName" : "The phototransduction cascade", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 2002, "y" : 309 }, "minX" : 1039, "maxX" : 2965, "minY" : -9, "maxY" : 628, "prop" : { "x" : 2228, "y" : -9, "width" : 737, "height" : 637 }, "points" : [ { "x" : 1039, "y" : -9 }, { "x" : 2965, "y" : -9 }, { "x" : 2965, "y" : 628 }, { "x" : 1039, "y" : 628 } ], "colour" : "#4684ee" }, { "id" : 128495, "reactomeId" : 10649708, "displayName" : "The retinoid cycle in cones (daylight vision)", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 1127, "y" : 1179 }, "minX" : 263, "maxX" : 1991, "minY" : 969, "maxY" : 1389, "prop" : { "x" : 263, "y" : 969, "width" : 1728, "height" : 420 }, "points" : [ { "x" : 263, "y" : 969 }, { "x" : 1991, "y" : 969 }, { "x" : 1991, "y" : 1389 }, { "x" : 263, "y" : 1389 } ], "colour" : "#008000" }, { "id" : 128494, "reactomeId" : 10647694, "displayName" : "The canonical retinoid cycle in rods (twilight vision)", "schemaClass" : "Pathway", "renderableClass" : "Shadow", "position" : { "x" : 1193, "y" : 437 }, "minX" : 159, "maxX" : 2228, "minY" : -9, "maxY" : 883, "prop" : { "x" : 159, "y" : -9, "width" : 880, "height" : 637 }, "points" : [ { "x" : 159, "y" : -9 }, { "x" : 2228, "y" : -9 }, { "x" : 2228, "y" : 883 }, { "x" : 159, "y" : 883 } ], "colour" : "#dc3912" } ], "minX" : 0, "maxX" : 3098, "minY" : 0, "maxY" : 1383, "disease" : false }