{
  "dbId" : 10912018,
  "stableId" : "R-DME-9959399",
  "displayName" : "SLC-mediated transport of oligopeptides",
  "nodes" : [ {
    "id" : 13392,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 403,
      "y" : 218
    },
    "minX" : 155,
    "maxX" : 420,
    "minY" : 113,
    "maxY" : 300,
    "prop" : {
      "x" : 387,
      "y" : 203,
      "width" : 32,
      "height" : 31
    },
    "textPosition" : {
      "x" : 389,
      "y" : 208
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 414,
          "y" : 208
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 414,
          "y" : 208
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 13395,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 390,
          "y" : 237
        },
        "to" : {
          "x" : 337,
          "y" : 300
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 389,
          "y" : 245
        },
        "b" : {
          "x" : 390,
          "y" : 237
        },
        "c" : {
          "x" : 382,
          "y" : 240
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 382,
          "y" : 240
        }
      }
    }, {
      "edgeId" : 13389,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 384,
          "y" : 211
        },
        "to" : {
          "x" : 155,
          "y" : 113
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 376,
          "y" : 212
        },
        "b" : {
          "x" : 384,
          "y" : 211
        },
        "c" : {
          "x" : 379,
          "y" : 205
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 379,
          "y" : 205
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 13393,
    "reactomeId" : 428026,
    "displayName" : "Di-peptides/tri-peptides",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySetDrug",
    "position" : {
      "x" : 158,
      "y" : 189
    },
    "minX" : 86,
    "maxX" : 230,
    "minY" : 113,
    "maxY" : 207,
    "prop" : {
      "x" : 86,
      "y" : 172,
      "width" : 144,
      "height" : 35
    },
    "textPosition" : {
      "x" : 108,
      "y" : 172
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 13389,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 157,
          "y" : 166
        },
        "to" : {
          "x" : 155,
          "y" : 113
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 153,
          "y" : 159
        },
        "b" : {
          "x" : 157,
          "y" : 166
        },
        "c" : {
          "x" : 161,
          "y" : 159
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 161,
          "y" : 159
        }
      }
    } ]
  }, {
    "id" : 13394,
    "reactomeId" : 10851472,
    "displayName" : "Homologues of SLC15A1",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 284,
      "y" : 113
    },
    "minX" : 164,
    "maxX" : 318,
    "minY" : 101,
    "maxY" : 126,
    "prop" : {
      "x" : 250,
      "y" : 101,
      "width" : 68,
      "height" : 25
    },
    "textPosition" : {
      "x" : 252,
      "y" : 89
    },
    "connectors" : [ {
      "edgeId" : 13389,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 247,
          "y" : 112
        },
        "to" : {
          "x" : 172,
          "y" : 112
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 168,
          "y" : 112
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 168,
          "y" : 112
        }
      }
    } ]
  }, {
    "id" : 13396,
    "reactomeId" : 5673778,
    "displayName" : "CySS-",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 316,
      "y" : 374
    },
    "minX" : 292,
    "maxX" : 341,
    "minY" : 301,
    "maxY" : 390,
    "prop" : {
      "x" : 292,
      "y" : 359,
      "width" : 48,
      "height" : 31
    },
    "textPosition" : {
      "x" : 295,
      "y" : 364
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 335,
          "y" : 364
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 335,
          "y" : 364
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 13395,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 320,
          "y" : 356
        },
        "to" : {
          "x" : 337,
          "y" : 301
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 13397,
    "reactomeId" : 428040,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 403,
      "y" : 349
    },
    "minX" : 337,
    "maxX" : 420,
    "minY" : 301,
    "maxY" : 365,
    "prop" : {
      "x" : 387,
      "y" : 334,
      "width" : 32,
      "height" : 31
    },
    "textPosition" : {
      "x" : 389,
      "y" : 339
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 414,
          "y" : 339
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 414,
          "y" : 339
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 13395,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 384,
          "y" : 337
        },
        "to" : {
          "x" : 337,
          "y" : 301
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 13398,
    "reactomeId" : 379444,
    "displayName" : "CySS-",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 306,
      "y" : 238
    },
    "minX" : 282,
    "maxX" : 337,
    "minY" : 222,
    "maxY" : 300,
    "prop" : {
      "x" : 282,
      "y" : 223,
      "width" : 48,
      "height" : 31
    },
    "textPosition" : {
      "x" : 285,
      "y" : 228
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 325,
          "y" : 228
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 325,
          "y" : 228
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 13395,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 313,
          "y" : 257
        },
        "to" : {
          "x" : 337,
          "y" : 300
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 320,
          "y" : 261
        },
        "b" : {
          "x" : 313,
          "y" : 257
        },
        "c" : {
          "x" : 313,
          "y" : 265
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 313,
          "y" : 265
        }
      }
    } ]
  }, {
    "id" : 13399,
    "reactomeId" : 10877175,
    "displayName" : "Ctns",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 260,
      "y" : 302
    },
    "minX" : 237,
    "maxX" : 330,
    "minY" : 285,
    "maxY" : 314,
    "prop" : {
      "x" : 237,
      "y" : 291,
      "width" : 46,
      "height" : 23
    },
    "textPosition" : {
      "x" : 242,
      "y" : 292
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 283,
          "y" : 291
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 283,
          "y" : 291
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 13395,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 286,
          "y" : 301
        },
        "to" : {
          "x" : 322,
          "y" : 301
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 326,
          "y" : 301
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 326,
          "y" : 301
        }
      }
    } ]
  }, {
    "id" : 13390,
    "reactomeId" : 351626,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 213,
      "y" : 62
    },
    "minX" : 157,
    "maxX" : 230,
    "minY" : 46,
    "maxY" : 112,
    "prop" : {
      "x" : 197,
      "y" : 47,
      "width" : 32,
      "height" : 31
    },
    "textPosition" : {
      "x" : 199,
      "y" : 52
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 224,
          "y" : 52
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 224,
          "y" : 52
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 13389,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 194,
          "y" : 76
        },
        "to" : {
          "x" : 157,
          "y" : 112
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 13391,
    "reactomeId" : 428037,
    "displayName" : "Di-peptides/tri-peptides",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySetDrug",
    "position" : {
      "x" : 158,
      "y" : 16
    },
    "minX" : 88,
    "maxX" : 228,
    "minY" : 0,
    "maxY" : 112,
    "prop" : {
      "x" : 88,
      "y" : 0,
      "width" : 140,
      "height" : 33
    },
    "textPosition" : {
      "x" : 108,
      "y" : -1
    },
    "bgColor" : {
      "r" : 184,
      "g" : 154,
      "b" : 230
    },
    "fgColor" : {
      "r" : 161,
      "g" : 1,
      "b" : 2
    },
    "connectors" : [ {
      "edgeId" : 13389,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 157,
          "y" : 39
        },
        "to" : {
          "x" : 157,
          "y" : 112
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 13395,
    "reactomeId" : 10877178,
    "displayName" : "CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 338,
      "y" : 301
    },
    "minX" : 332,
    "maxX" : 344,
    "minY" : 295,
    "maxY" : 307,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 337,
        "y" : 301
      },
      "to" : {
        "x" : 338,
        "y" : 301
      }
    }, {
      "from" : {
        "x" : 338,
        "y" : 301
      },
      "to" : {
        "x" : 337,
        "y" : 300
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 332,
        "y" : 295
      },
      "b" : {
        "x" : 344,
        "y" : 307
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 338,
        "y" : 301
      }
    },
    "inputs" : [ {
      "id" : 13396,
      "points" : [ {
        "x" : 320,
        "y" : 356
      } ]
    }, {
      "id" : 13397,
      "points" : [ {
        "x" : 384,
        "y" : 337
      } ]
    } ],
    "outputs" : [ {
      "id" : 13398,
      "points" : [ {
        "x" : 313,
        "y" : 257
      } ]
    }, {
      "id" : 13392,
      "points" : [ {
        "x" : 390,
        "y" : 237
      } ]
    } ],
    "catalysts" : [ {
      "id" : 13399,
      "points" : [ {
        "x" : 286,
        "y" : 301
      } ]
    } ]
  }, {
    "id" : 13389,
    "reactomeId" : 10851475,
    "displayName" : "SLC25A1 transports di-/tri-peptides and peptide-like drugs",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 156,
      "y" : 112
    },
    "minX" : 151,
    "maxX" : 163,
    "minY" : 106,
    "maxY" : 118,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 157,
        "y" : 112
      },
      "to" : {
        "x" : 156,
        "y" : 112
      }
    }, {
      "from" : {
        "x" : 156,
        "y" : 112
      },
      "to" : {
        "x" : 155,
        "y" : 113
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 150,
        "y" : 106
      },
      "b" : {
        "x" : 162,
        "y" : 118
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 156,
        "y" : 112
      }
    },
    "inputs" : [ {
      "id" : 13390,
      "points" : [ {
        "x" : 194,
        "y" : 76
      } ]
    }, {
      "id" : 13391,
      "points" : [ {
        "x" : 157,
        "y" : 39
      } ]
    } ],
    "outputs" : [ {
      "id" : 13392,
      "points" : [ {
        "x" : 384,
        "y" : 211
      } ]
    }, {
      "id" : 13393,
      "points" : [ {
        "x" : 157,
        "y" : 166
      } ]
    } ],
    "catalysts" : [ {
      "id" : 13394,
      "points" : [ {
        "x" : 247,
        "y" : 112
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 13400,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 600,
      "y" : 340
    },
    "minX" : 0,
    "maxX" : 1200,
    "minY" : 107,
    "maxY" : 573,
    "prop" : {
      "x" : 0,
      "y" : 107,
      "width" : 1200,
      "height" : 466
    },
    "textPosition" : {
      "x" : 747,
      "y" : 378
    },
    "insets" : {
      "x" : 10,
      "y" : 117,
      "width" : 1180,
      "height" : 446
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 13392, 13394, 13389, 13401, 13393, 13398 ]
  }, {
    "id" : 13401,
    "reactomeId" : 161320,
    "displayName" : "lysosomal lumen",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 443,
      "y" : 414
    },
    "minX" : 214,
    "maxX" : 672,
    "minY" : 296,
    "maxY" : 532,
    "prop" : {
      "x" : 214,
      "y" : 296,
      "width" : 458,
      "height" : 236
    },
    "textPosition" : {
      "x" : 466,
      "y" : 478
    },
    "insets" : {
      "x" : 224,
      "y" : 306,
      "width" : 438,
      "height" : 216
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 13397, 13399, 13396, 13395 ]
  } ],
  "notes" : [ ],
  "links" : [ ],
  "shadows" : [ {
    "id" : 13402,
    "reactomeId" : 10912016,
    "displayName" : "Proton/oligopeptide cotransporters",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 252,
      "y" : 117
    },
    "minX" : 76,
    "maxX" : 429,
    "minY" : -10,
    "maxY" : 244,
    "prop" : {
      "x" : 76,
      "y" : -10,
      "width" : 353,
      "height" : 254
    },
    "points" : [ {
      "x" : 76,
      "y" : -10
    }, {
      "x" : 429,
      "y" : -10
    }, {
      "x" : 429,
      "y" : 244
    }, {
      "x" : 76,
      "y" : 244
    } ],
    "colour" : "#4684ee"
  } ],
  "minX" : 0,
  "maxX" : 1200,
  "minY" : 0,
  "maxY" : 573,
  "disease" : false
}