{
  "dbId" : 10913350,
  "stId" : "R-DME-9755088",
  "speciesName" : "Drosophila melanogaster",
  "nodes" : [ {
    "dbId" : 9755028,
    "stId" : "R-ALL-9755028",
    "displayName" : "RBV-MP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118804, 118813 ],
    "identifier" : "189091",
    "standardIdentifier" : "chebi:189091",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 74113,
    "stId" : "R-ALL-74113",
    "displayName" : "Na+ [extracellular region]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118797 ],
    "identifier" : "29101",
    "standardIdentifier" : "chebi:29101",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10855846,
    "stId" : "R-DME-60022",
    "displayName" : "NME1 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "P08879",
    "standardIdentifier" : "uniprot:P08879",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10855848 ],
    "children" : [ ]
  }, {
    "dbId" : 83910,
    "stId" : "R-ALL-83910",
    "displayName" : "Na+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118798 ],
    "identifier" : "29101",
    "standardIdentifier" : "chebi:29101",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10833517,
    "stId" : "R-DME-61933",
    "displayName" : "CG16760 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "M9PE19",
    "standardIdentifier" : "uniprot:M9PE19",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CG16760" ],
    "parents" : [ 10833524 ],
    "children" : [ ]
  }, {
    "dbId" : 9754909,
    "stId" : "R-ALL-9754909",
    "displayName" : "T-CONH2 [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118818 ],
    "identifier" : "180482",
    "standardIdentifier" : "chebi:180482",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10871532,
    "stId" : "R-DME-2509850",
    "displayName" : "ITPA [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VMW7",
    "standardIdentifier" : "uniprot:Q9VMW7",
    "referenceType" : "ReferenceGeneProduct",
    "parents" : [ 10871534 ],
    "children" : [ ]
  }, {
    "dbId" : 10871534,
    "stId" : "R-DME-2509833",
    "displayName" : "ITPA dimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 118805 ],
    "parents" : [ ],
    "children" : [ 10871532 ]
  }, {
    "dbId" : 10855848,
    "stId" : "R-DME-482626",
    "displayName" : "nucleoside diphosphate kinase 1A:5B heterohexamer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 118810 ],
    "parents" : [ ],
    "children" : [ 10855846 ]
  }, {
    "dbId" : 9680963,
    "stId" : "R-ALL-9680963",
    "displayName" : "RBV [cytosol]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "diagramIds" : [ 118790, 118795 ],
    "identifier" : "6842",
    "standardIdentifier" : "iuphar.ligand:6842",
    "chebiIdentifier" : "chebi:63580",
    "parents" : [ 9754954 ],
    "children" : [ ]
  }, {
    "dbId" : 10833524,
    "stId" : "R-DME-61933-3",
    "displayName" : "Homologues of PNP [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10833526 ],
    "children" : [ 10833517, 10833522 ]
  }, {
    "dbId" : 112016,
    "stId" : "R-ALL-112016",
    "displayName" : "R1P [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118819 ],
    "identifier" : "57720",
    "standardIdentifier" : "chebi:57720",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 9754951,
    "stId" : "R-ALL-9754951",
    "displayName" : "RBV-TP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118802 ],
    "identifier" : "189093",
    "standardIdentifier" : "chebi:189093",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 9754954 ],
    "children" : [ ]
  }, {
    "dbId" : 10833526,
    "stId" : "R-DME-74237",
    "displayName" : "PNP trimer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 118820 ],
    "parents" : [ ],
    "children" : [ 10833524 ]
  }, {
    "dbId" : 83927,
    "stId" : "R-ALL-83927",
    "displayName" : "Ino [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118823 ],
    "identifier" : "17596",
    "standardIdentifier" : "chebi:17596",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 9755011,
    "stId" : "R-ALL-9755011",
    "displayName" : "phosphate [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118817, 118830 ],
    "identifier" : "18367",
    "standardIdentifier" : "chebi:18367",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10833522,
    "stId" : "R-DME-61933-2",
    "displayName" : "Dmel\\CG18128 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9W1K6",
    "standardIdentifier" : "uniprot:Q9W1K6",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Dmel\\CG18128" ],
    "parents" : [ 10833524 ],
    "children" : [ ]
  }, {
    "dbId" : 10835581,
    "stId" : "R-DME-64025",
    "displayName" : "CNT1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "A1Z7N3",
    "standardIdentifier" : "uniprot:A1Z7N3",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CNT1" ],
    "parents" : [ 10835585 ],
    "children" : [ ]
  }, {
    "dbId" : 10905020,
    "stId" : "R-DME-9751044",
    "displayName" : "SLC28A2,3 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "diagramIds" : [ 118799 ],
    "parents" : [ ],
    "children" : [ 10835576, 10835585 ]
  }, {
    "dbId" : 10835583,
    "stId" : "R-DME-64025-2",
    "displayName" : "CNT2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7K4A1",
    "standardIdentifier" : "uniprot:Q7K4A1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CNT2" ],
    "parents" : [ 10835585 ],
    "children" : [ ]
  }, {
    "dbId" : 10835576,
    "stId" : "R-DME-83915",
    "displayName" : "CNT2 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q7K4A1",
    "standardIdentifier" : "uniprot:Q7K4A1",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "CNT2" ],
    "parents" : [ 10905020 ],
    "children" : [ ]
  }, {
    "dbId" : 9755082,
    "stId" : "R-ALL-9755082",
    "displayName" : "RBV [extracellular region]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "diagramIds" : [ 118791, 118794 ],
    "identifier" : "6842",
    "standardIdentifier" : "iuphar.ligand:6842",
    "chebiIdentifier" : "chebi:63580",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 9754954,
    "stId" : "R-ALL-9754954",
    "displayName" : "RBV,RBV-TP [cytosol]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 0,
    "diagramIds" : [ 118826 ],
    "parents" : [ ],
    "children" : [ 9754951, 9680963 ]
  }, {
    "dbId" : 9754996,
    "stId" : "R-ALL-9754996",
    "displayName" : "RBV,RBV-TP [mitochondrial matrix]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 0,
    "diagramIds" : [ 118827 ],
    "parents" : [ ],
    "children" : [ 9755006, 9755045 ]
  }, {
    "dbId" : 29602,
    "stId" : "R-ALL-29602",
    "displayName" : "IMP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118822 ],
    "identifier" : "58053",
    "standardIdentifier" : "chebi:58053",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10835585,
    "stId" : "R-DME-64025-3",
    "displayName" : "Homologues of SLC28A2 [plasma membrane]",
    "schemaClass" : "DefinedSet",
    "speciesId" : 56210,
    "parents" : [ 10905020 ],
    "children" : [ 10835583, 10835581 ]
  }, {
    "dbId" : 29926,
    "stId" : "R-ALL-29926",
    "displayName" : "Mg2+ [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "18420",
    "standardIdentifier" : "chebi:18420",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 10835595, 10833546 ],
    "children" : [ ]
  }, {
    "dbId" : 9755006,
    "stId" : "R-ALL-9755006",
    "displayName" : "ribavirin [mitochondrial matrix]",
    "schemaClass" : "ChemicalDrug",
    "speciesId" : 0,
    "identifier" : "6842",
    "standardIdentifier" : "iuphar.ligand:6842",
    "chebiIdentifier" : "chebi:63580",
    "parents" : [ 9754996 ],
    "children" : [ ]
  }, {
    "dbId" : 10835593,
    "stId" : "R-DME-49725",
    "displayName" : "Adk2 [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VU38",
    "standardIdentifier" : "uniprot:Q9VU38",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Adk2" ],
    "parents" : [ 10835595 ],
    "children" : [ ]
  }, {
    "dbId" : 29356,
    "stId" : "R-ALL-29356",
    "displayName" : "H2O [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118801 ],
    "identifier" : "15377",
    "standardIdentifier" : "chebi:15377",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10833544,
    "stId" : "R-DME-49189",
    "displayName" : "Nt5b [cytosol]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "identifier" : "Q9VWV5",
    "standardIdentifier" : "uniprot:Q9VWV5",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Nt5b" ],
    "parents" : [ 10833546 ],
    "children" : [ ]
  }, {
    "dbId" : 10835595,
    "stId" : "R-DME-76542",
    "displayName" : "ADK [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 118815 ],
    "parents" : [ ],
    "children" : [ 10835593, 29926 ]
  }, {
    "dbId" : 10833546,
    "stId" : "R-DME-109318",
    "displayName" : "NT5C2 tetramer [cytosol]",
    "schemaClass" : "Complex",
    "speciesId" : 56210,
    "diagramIds" : [ 118824, 118831 ],
    "parents" : [ ],
    "children" : [ 10833544, 29926 ]
  }, {
    "dbId" : 9755045,
    "stId" : "R-ALL-9755045",
    "displayName" : "RBV-TP [mitochondrial matrix]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "identifier" : "189093",
    "standardIdentifier" : "chebi:189093",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ 9754996 ],
    "children" : [ ]
  }, {
    "dbId" : 10905054,
    "stId" : "R-DME-9754911",
    "displayName" : "Ent1 [mitochondrial outer membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 118828 ],
    "identifier" : "Q9VPP0",
    "standardIdentifier" : "uniprot:Q9VPP0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ent1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 10835549,
    "stId" : "R-DME-54335",
    "displayName" : "Ent1 [plasma membrane]",
    "schemaClass" : "EntityWithAccessionedSequence",
    "speciesId" : 56210,
    "diagramIds" : [ 118792 ],
    "identifier" : "Q9VPP0",
    "standardIdentifier" : "uniprot:Q9VPP0",
    "referenceType" : "ReferenceGeneProduct",
    "geneNames" : [ "Ent1" ],
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 113592,
    "stId" : "R-ALL-113592",
    "displayName" : "ATP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118807, 118812 ],
    "identifier" : "30616",
    "standardIdentifier" : "chebi:30616",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 29370,
    "stId" : "R-ALL-29370",
    "displayName" : "ADP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118809, 118814 ],
    "identifier" : "456216",
    "standardIdentifier" : "chebi:456216",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 9754985,
    "stId" : "R-ALL-9754985",
    "displayName" : "RBV-DP [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118808 ],
    "identifier" : "189092",
    "standardIdentifier" : "chebi:189092",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  }, {
    "dbId" : 111294,
    "stId" : "R-ALL-111294",
    "displayName" : "PPi [cytosol]",
    "schemaClass" : "SimpleEntity",
    "speciesId" : 0,
    "diagramIds" : [ 118803 ],
    "identifier" : "33019",
    "standardIdentifier" : "chebi:33019",
    "chebiIdentifier" : "chebi:33019",
    "referenceType" : "ReferenceMolecule",
    "parents" : [ ],
    "children" : [ ]
  } ],
  "edges" : [ {
    "dbId" : 10905063,
    "stId" : "R-DME-9755013",
    "displayName" : "NME1,2 hexamers phosphorylate RBV-DP",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10905057, 10905068 ],
    "inputs" : [ 9754985, 113592 ],
    "outputs" : [ 29370, 9754951 ],
    "catalysts" : [ 10855848 ],
    "efs" : [ ],
    "diagramIds" : [ 118806 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10905061,
    "stId" : "R-DME-9754974",
    "displayName" : "ADK phosphorylates RBV",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10905059 ],
    "following" : [ 10905074 ],
    "inputs" : [ 113592, 9680963 ],
    "outputs" : [ 29370, 9755028 ],
    "catalysts" : [ 10835595 ],
    "efs" : [ ],
    "diagramIds" : [ 118811 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10905074,
    "stId" : "R-DME-9755078",
    "displayName" : "NT5C2 tetramer dephosphorylates RBV-MP",
    "schemaClass" : "BlackBoxEvent",
    "speciesId" : 0,
    "preceding" : [ 10905068, 10905052, 10905061 ],
    "following" : [ 10905057, 10905072 ],
    "inputs" : [ 29356, 9755028 ],
    "outputs" : [ 9755011, 9680963 ],
    "catalysts" : [ 10833546 ],
    "efs" : [ ],
    "diagramIds" : [ 118829 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10905059,
    "stId" : "R-DME-9754934",
    "displayName" : "SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10905070 ],
    "following" : [ 10905057, 10905072, 10905061, 10905052, 10905070 ],
    "inputs" : [ 9755082, 74113 ],
    "outputs" : [ 83910, 9680963 ],
    "catalysts" : [ 10905020 ],
    "efs" : [ ],
    "diagramIds" : [ 118796 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10905072,
    "stId" : "R-DME-9755044",
    "displayName" : "PNP trimer transforms RBV to T-CONH2",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10905065, 10905059, 10905074 ],
    "inputs" : [ 9755011, 9680963 ],
    "outputs" : [ 9754909, 112016 ],
    "catalysts" : [ 10833526 ],
    "efs" : [ ],
    "diagramIds" : [ 118816 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10905057,
    "stId" : "R-DME-9754929",
    "displayName" : "SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10905065, 10905059, 10905074, 10905063 ],
    "inputs" : [ 9754954 ],
    "outputs" : [ 9754996 ],
    "catalysts" : [ 10905054 ],
    "efs" : [ ],
    "diagramIds" : [ 118825 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10905070,
    "stId" : "R-DME-9755035",
    "displayName" : "SLC29A1 transports RBV from cytosol to extracellular region",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10905059 ],
    "following" : [ 10905059 ],
    "inputs" : [ 9680963 ],
    "outputs" : [ 9755082 ],
    "catalysts" : [ 10835549 ],
    "efs" : [ ],
    "diagramIds" : [ 118789 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10905052,
    "stId" : "R-DME-9754916",
    "displayName" : "NT5C2 tetramer phosphorylates RBV",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10905059 ],
    "following" : [ 10905074 ],
    "inputs" : [ 29602, 9680963 ],
    "outputs" : [ 83927, 9755028 ],
    "catalysts" : [ 10833546 ],
    "efs" : [ ],
    "diagramIds" : [ 118821 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10905068,
    "stId" : "R-DME-9755030",
    "displayName" : "ITPA dimer dephosphorylates RBV-TP to RBV-MP",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "preceding" : [ 10905063 ],
    "following" : [ 10905074 ],
    "inputs" : [ 29356, 9754951 ],
    "outputs" : [ 111294, 9755028 ],
    "catalysts" : [ 10871534 ],
    "efs" : [ ],
    "diagramIds" : [ 118800 ],
    "entityFunctionalStatus" : [ ]
  }, {
    "dbId" : 10905065,
    "stId" : "R-DME-9755015",
    "displayName" : "SLC29A1 transports RBV from extracellular region to cytosol",
    "schemaClass" : "Reaction",
    "speciesId" : 0,
    "following" : [ 10905057, 10905072 ],
    "inputs" : [ 9755082 ],
    "outputs" : [ 9680963 ],
    "catalysts" : [ 10835549 ],
    "efs" : [ ],
    "diagramIds" : [ 118793 ],
    "entityFunctionalStatus" : [ ]
  } ]
}